Motif ID: Zbtb4
Z-value: 0.625
Transcription factors associated with Zbtb4:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Zbtb4 | ENSMUSG00000018750.8 | Zbtb4 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Zbtb4 | mm10_v2_chr11_+_69765970_69766027 | 0.55 | 1.9e-02 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 74 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.7 | GO:0044268 | multicellular organismal protein metabolic process(GO:0044268) |
| 0.1 | 1.2 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.1 | 1.1 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
| 0.0 | 1.1 | GO:0010960 | magnesium ion homeostasis(GO:0010960) |
| 0.2 | 0.9 | GO:0051643 | endoplasmic reticulum localization(GO:0051643) |
| 0.1 | 0.9 | GO:0035093 | spermatogenesis, exchange of chromosomal proteins(GO:0035093) |
| 0.1 | 0.9 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 0.2 | 0.8 | GO:1901492 | positive regulation of lymphangiogenesis(GO:1901492) |
| 0.0 | 0.7 | GO:0007614 | short-term memory(GO:0007614) |
| 0.0 | 0.7 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.2 | 0.6 | GO:0098928 | presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526) |
| 0.2 | 0.6 | GO:1903002 | regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002) |
| 0.2 | 0.6 | GO:0032430 | inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466) |
| 0.1 | 0.6 | GO:2000325 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
| 0.1 | 0.6 | GO:0061718 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
| 0.1 | 0.6 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
| 0.1 | 0.6 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.1 | 0.6 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
| 0.0 | 0.6 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
| 0.1 | 0.5 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 31 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.2 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.0 | 1.1 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.1 | 1.0 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.3 | 0.9 | GO:0042642 | actomyosin, myosin complex part(GO:0042642) |
| 0.0 | 0.7 | GO:0000795 | synaptonemal complex(GO:0000795) |
| 0.0 | 0.7 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
| 0.0 | 0.7 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.2 | 0.6 | GO:1990257 | piccolo-bassoon transport vesicle(GO:1990257) |
| 0.2 | 0.6 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
| 0.0 | 0.6 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.0 | 0.6 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.0 | 0.6 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.2 | 0.5 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
| 0.0 | 0.5 | GO:0043203 | axon hillock(GO:0043203) |
| 0.0 | 0.5 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.0 | 0.5 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.1 | 0.4 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.1 | 0.4 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 0.0 | 0.4 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 0.4 | GO:0097470 | ribbon synapse(GO:0097470) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 60 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 1.7 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
| 0.0 | 1.5 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.3 | 1.2 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
| 0.3 | 1.2 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
| 0.1 | 1.1 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
| 0.1 | 0.9 | GO:0046790 | virion binding(GO:0046790) |
| 0.0 | 0.9 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
| 0.0 | 0.8 | GO:0005518 | collagen binding(GO:0005518) |
| 0.2 | 0.7 | GO:0004609 | phosphatidylserine decarboxylase activity(GO:0004609) |
| 0.1 | 0.7 | GO:0046404 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
| 0.0 | 0.7 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.2 | 0.6 | GO:0046911 | hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
| 0.1 | 0.6 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
| 0.1 | 0.6 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
| 0.1 | 0.6 | GO:0008865 | fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.0 | 0.6 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.0 | 0.6 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.0 | 0.6 | GO:0005112 | Notch binding(GO:0005112) |
| 0.1 | 0.5 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.1 | 0.5 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
Gene overrepresentation in C2:CP category:
Showing 1 to 5 of 5 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 0.7 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.6 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.0 | 0.6 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 0.4 | PID_ARF_3PATHWAY | Arf1 pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 20 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.9 | REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
| 0.0 | 1.3 | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.1 | 1.2 | REACTOME_TRANSPORT_OF_ORGANIC_ANIONS | Genes involved in Transport of organic anions |
| 0.0 | 0.9 | REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 0.0 | 0.7 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 0.7 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 0.6 | REACTOME_HDL_MEDIATED_LIPID_TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.0 | 0.6 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.0 | 0.6 | REACTOME_GLUCOSE_TRANSPORT | Genes involved in Glucose transport |
| 0.0 | 0.5 | REACTOME_SIGNALING_BY_ROBO_RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 0.4 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.0 | 0.4 | REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY | Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway |
| 0.0 | 0.4 | REACTOME_SIGNALING_BY_BMP | Genes involved in Signaling by BMP |
| 0.0 | 0.3 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
| 0.0 | 0.3 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
| 0.0 | 0.2 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.0 | 0.2 | REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
| 0.0 | 0.2 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.0 | 0.1 | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.0 | 0.1 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
