Motif ID: Zbtb49

Z-value: 0.511


Transcription factors associated with Zbtb49:

Gene SymbolEntrez IDGene Name
Zbtb49 ENSMUSG00000029127.9 Zbtb49

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb49mm10_v2_chr5_-_38220400_382204590.662.9e-03Click!


Activity profile for motif Zbtb49.

activity profile for motif Zbtb49


Sorted Z-values histogram for motif Zbtb49

Sorted Z-values for motif Zbtb49



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb49

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_45430293 2.008 ENSMUST00000034592.8
 Dscaml1
Down syndrome cell adhesion molecule like 1
chr7_-_140154712 2.006 ENSMUST00000059241.7
 Sprn
shadow of prion protein
chr9_+_40269430 1.206 ENSMUST00000171835.2
 Scn3b
sodium channel, voltage-gated, type III, beta
chr12_+_89812467 1.172 ENSMUST00000110133.2
ENSMUST00000110130.2
 Nrxn3

neurexin III

chr18_-_61911783 1.149 ENSMUST00000049378.8
ENSMUST00000166783.1
 Ablim3

actin binding LIM protein family, member 3

chr9_+_40269273 1.075 ENSMUST00000176185.1
 Scn3b
sodium channel, voltage-gated, type III, beta
chr9_+_40269202 1.055 ENSMUST00000114956.3
ENSMUST00000049941.5
 Scn3b

sodium channel, voltage-gated, type III, beta

chr15_-_102257306 0.601 ENSMUST00000135466.1
 Rarg
retinoic acid receptor, gamma
chr1_+_32172711 0.579 ENSMUST00000027226.5
 Khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr18_+_23753708 0.576 ENSMUST00000115830.1
 Mapre2
microtubule-associated protein, RP/EB family, member 2
chr5_-_108629712 0.565 ENSMUST00000046603.8
 Gak
cyclin G associated kinase
chr9_+_50856924 0.554 ENSMUST00000174628.1
ENSMUST00000034560.7
ENSMUST00000114437.2
ENSMUST00000175645.1
ENSMUST00000176349.1
ENSMUST00000176798.1
ENSMUST00000175640.1
 Ppp2r1b






protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform






chr15_-_102257449 0.538 ENSMUST00000043172.8
 Rarg
retinoic acid receptor, gamma
chr5_+_108629990 0.370 ENSMUST00000078323.6
ENSMUST00000120327.1
 Tmem175

transmembrane protein 175

chr8_+_4493443 0.314 ENSMUST00000175781.2
 Cers4
ceramide synthase 4
chr14_-_68655804 0.252 ENSMUST00000111072.1
ENSMUST00000022642.5
 Adam28

a disintegrin and metallopeptidase domain 28

chr5_+_108629791 0.247 ENSMUST00000063272.6
 Tmem175
transmembrane protein 175
chr3_-_53017195 0.227 ENSMUST00000036665.4
 Cog6
component of oligomeric golgi complex 6
chr1_-_183369529 0.202 ENSMUST00000069922.5
 Mia3
melanoma inhibitory activity 3
chr7_+_4460687 0.179 ENSMUST00000167298.1
ENSMUST00000171445.1
 Eps8l1

EPS8-like 1

chr6_+_59208870 0.136 ENSMUST00000062626.3
 Tigd2
tigger transposable element derived 2
chr17_+_32993123 0.132 ENSMUST00000087666.4
ENSMUST00000157017.1
 Zfp952

zinc finger protein 952

chr16_-_70382385 0.129 ENSMUST00000072455.4
 4930423O20Rik
RIKEN cDNA 4930423O20 gene
chr15_-_100422991 0.116 ENSMUST00000138843.1
ENSMUST00000023774.5
 Slc11a2

solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2

chrX_-_153696195 0.101 ENSMUST00000039424.8
ENSMUST00000112572.1
 Kctd12b

potassium channel tetramerisation domain containing 12b


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.3 GO:0060373 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.3 1.1 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.3 2.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 0.6 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 0.6 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 1.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.6 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 1.1 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 2.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.3 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.2 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 1.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.6 GO:0008143 poly(A) binding(GO:0008143)
0.0 1.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.6 GO:0030332 cyclin binding(GO:0030332)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 3.3 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.1 3.3 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.1 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.6 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 1.1 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway