Motif ID: Zbtb7a

Z-value: 0.631


Transcription factors associated with Zbtb7a:

Gene SymbolEntrez IDGene Name
Zbtb7a ENSMUSG00000035011.9 Zbtb7a

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb7amm10_v2_chr10_+_81137953_811379920.663.1e-03Click!


Activity profile for motif Zbtb7a.

activity profile for motif Zbtb7a


Sorted Z-values histogram for motif Zbtb7a

Sorted Z-values for motif Zbtb7a



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb7a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_44234014 1.994 ENSMUST00000037644.6
Cbl
Casitas B-lineage lymphoma
chr8_-_11008458 1.841 ENSMUST00000040514.6
Irs2
insulin receptor substrate 2
chr7_+_96210107 1.534 ENSMUST00000138760.1
Tenm4
teneurin transmembrane protein 4
chr7_+_49246812 1.451 ENSMUST00000184945.1
Nav2
neuron navigator 2
chr18_+_32938955 1.410 ENSMUST00000042868.4
Camk4
calcium/calmodulin-dependent protein kinase IV
chr16_+_11984581 1.369 ENSMUST00000170672.2
ENSMUST00000023138.7
Shisa9

shisa homolog 9 (Xenopus laevis)

chr11_-_107915041 1.347 ENSMUST00000039071.2
Cacng5
calcium channel, voltage-dependent, gamma subunit 5
chr8_-_34965631 1.313 ENSMUST00000033929.4
Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr5_+_37028329 1.283 ENSMUST00000173836.1
Jakmip1
janus kinase and microtubule interacting protein 1
chr11_+_24076529 1.213 ENSMUST00000148087.1
Gm12063
predicted gene 12063
chr9_+_100643755 1.211 ENSMUST00000133388.1
Stag1
stromal antigen 1
chr4_-_123664725 1.189 ENSMUST00000147030.1
Macf1
microtubule-actin crosslinking factor 1
chr15_-_100599864 1.164 ENSMUST00000177247.2
ENSMUST00000177505.2
Pou6f1

POU domain, class 6, transcription factor 1

chr2_+_180499893 1.095 ENSMUST00000029084.2
Ntsr1
neurotensin receptor 1
chr15_-_98567630 1.047 ENSMUST00000012104.6
Ccnt1
cyclin T1
chr5_-_139129662 1.044 ENSMUST00000026973.7
Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr1_+_86045863 1.039 ENSMUST00000165824.1
2810459M11Rik
RIKEN cDNA 2810459M11 gene
chr11_+_75532127 0.972 ENSMUST00000127226.1
Slc43a2
solute carrier family 43, member 2
chr17_-_17624458 0.954 ENSMUST00000041047.2
Lnpep
leucyl/cystinyl aminopeptidase
chr6_+_54681687 0.948 ENSMUST00000046276.6
2410066E13Rik
RIKEN cDNA 2410066E13 gene
chr8_+_70493156 0.935 ENSMUST00000008032.7
Crlf1
cytokine receptor-like factor 1
chr11_+_75531690 0.888 ENSMUST00000149727.1
ENSMUST00000042561.7
ENSMUST00000108433.1
ENSMUST00000143035.1
Slc43a2



solute carrier family 43, member 2



chr17_+_6270475 0.884 ENSMUST00000088940.4
Tmem181a
transmembrane protein 181A
chr9_+_67840386 0.884 ENSMUST00000077879.5
Vps13c
vacuolar protein sorting 13C (yeast)
chrX_+_159697308 0.882 ENSMUST00000123433.1
Sh3kbp1
SH3-domain kinase binding protein 1
chr7_-_73537621 0.872 ENSMUST00000172704.1
Chd2
chromodomain helicase DNA binding protein 2
chrX_+_71364901 0.871 ENSMUST00000132837.1
Mtmr1
myotubularin related protein 1
chr1_-_155417394 0.869 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chr2_-_29253001 0.863 ENSMUST00000071201.4
Ntng2
netrin G2
chr1_-_154725920 0.845 ENSMUST00000004214.8
Cacna1e
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr13_-_59556845 0.829 ENSMUST00000170378.1
ENSMUST00000169434.1
Agtpbp1

ATP/GTP binding protein 1

chr10_-_127263346 0.794 ENSMUST00000099172.3
Kif5a
kinesin family member 5A
chr1_+_132008285 0.793 ENSMUST00000146432.1
Elk4
ELK4, member of ETS oncogene family
chr2_+_172345565 0.789 ENSMUST00000028995.4
Fam210b
family with sequence similarity 210, member B
chr11_+_68692070 0.787 ENSMUST00000108673.1
Myh10
myosin, heavy polypeptide 10, non-muscle
chr4_-_22488296 0.785 ENSMUST00000178174.1
Pou3f2
POU domain, class 3, transcription factor 2
chr11_-_70687917 0.777 ENSMUST00000108545.2
ENSMUST00000120261.1
ENSMUST00000036299.7
ENSMUST00000119120.1
ENSMUST00000100933.3
Camta2




calmodulin binding transcription activator 2




chr2_+_180042496 0.776 ENSMUST00000041126.8
Ss18l1
synovial sarcoma translocation gene on chromosome 18-like 1
chr16_+_91729436 0.773 ENSMUST00000113993.1
Itsn1
intersectin 1 (SH3 domain protein 1A)
chr17_-_66077022 0.768 ENSMUST00000150766.1
ENSMUST00000038116.5
Ankrd12

ankyrin repeat domain 12

chr6_-_126645784 0.756 ENSMUST00000055168.3
Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
chr8_+_40862379 0.742 ENSMUST00000098816.3
ENSMUST00000057784.8
ENSMUST00000141505.1
Slc7a2


solute carrier family 7 (cationic amino acid transporter, y+ system), member 2


chr3_+_107036156 0.735 ENSMUST00000052718.3
Kcna3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr18_+_35965088 0.726 ENSMUST00000175734.1
Psd2
pleckstrin and Sec7 domain containing 2
chr4_+_136284658 0.723 ENSMUST00000144217.1
Zfp46
zinc finger protein 46
chr2_-_25319095 0.702 ENSMUST00000114318.3
ENSMUST00000114310.3
ENSMUST00000114308.3
ENSMUST00000114317.3
ENSMUST00000028335.6
ENSMUST00000114314.3
ENSMUST00000114307.1
Grin1






glutamate receptor, ionotropic, NMDA1 (zeta 1)






chr16_+_91729281 0.701 ENSMUST00000114001.1
ENSMUST00000113999.1
ENSMUST00000064797.5
ENSMUST00000114002.2
ENSMUST00000095909.3
ENSMUST00000056482.7
ENSMUST00000113996.1
Itsn1






intersectin 1 (SH3 domain protein 1A)






chr4_-_139075557 0.698 ENSMUST00000105802.1
Htr6
5-hydroxytryptamine (serotonin) receptor 6
chr11_+_49794157 0.698 ENSMUST00000020629.4
Gfpt2
glutamine fructose-6-phosphate transaminase 2
chr4_+_103619580 0.695 ENSMUST00000106827.1
Dab1
disabled 1
chr11_-_118248489 0.687 ENSMUST00000100181.4
Cyth1
cytohesin 1
chr16_+_36875119 0.681 ENSMUST00000135406.1
ENSMUST00000114812.1
ENSMUST00000134616.1
ENSMUST00000023534.6
Golgb1


Golgb1
golgi autoantigen, golgin subfamily b, macrogolgin 1


golgi autoantigen, golgin subfamily b, macrogolgin 1
chr9_+_66350465 0.670 ENSMUST00000042824.6
Herc1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr13_+_54575020 0.664 ENSMUST00000156024.1
Arl10
ADP-ribosylation factor-like 10
chr11_+_3332426 0.657 ENSMUST00000136474.1
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr11_-_70229677 0.654 ENSMUST00000153449.1
ENSMUST00000000326.5
Bcl6b

B cell CLL/lymphoma 6, member B

chr16_-_43979050 0.640 ENSMUST00000165648.1
ENSMUST00000036321.7
Zdhhc23

zinc finger, DHHC domain containing 23

chr7_-_27929430 0.639 ENSMUST00000098639.2
1700049G17Rik
RIKEN cDNA 1700049G17 gene
chr1_-_21961581 0.637 ENSMUST00000029667.6
ENSMUST00000173058.1
ENSMUST00000173404.1
Kcnq5


potassium voltage-gated channel, subfamily Q, member 5


chr16_+_10545390 0.635 ENSMUST00000115827.1
ENSMUST00000038145.6
ENSMUST00000150894.1
Clec16a


C-type lectin domain family 16, member A


chr4_-_151108244 0.632 ENSMUST00000131948.1
Camta1
calmodulin binding transcription activator 1
chr9_+_31280525 0.631 ENSMUST00000117389.1
Prdm10
PR domain containing 10
chr10_+_88379127 0.617 ENSMUST00000127615.1
Gnptab
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr4_+_136284708 0.615 ENSMUST00000130223.1
Zfp46
zinc finger protein 46
chr15_-_28025834 0.610 ENSMUST00000090247.5
Trio
triple functional domain (PTPRF interacting)
chr5_+_130144861 0.610 ENSMUST00000040616.2
Kctd7
potassium channel tetramerisation domain containing 7
chr10_+_76531593 0.602 ENSMUST00000048678.6
Lss
lanosterol synthase
chr7_+_127511976 0.600 ENSMUST00000098025.4
Srcap
Snf2-related CREBBP activator protein
chr17_-_78835326 0.592 ENSMUST00000097281.2
Heatr5b
HEAT repeat containing 5B
chr3_+_118433797 0.591 ENSMUST00000180593.1
ENSMUST00000181926.1
ENSMUST00000181060.1
ENSMUST00000181310.1
Gm26871



predicted gene, 26871



chr2_-_5676046 0.591 ENSMUST00000114987.3
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr12_+_86241848 0.590 ENSMUST00000071106.4
Gpatch2l
G patch domain containing 2 like
chr3_+_117575268 0.590 ENSMUST00000039564.6
4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr10_-_17947997 0.588 ENSMUST00000037879.6
Heca
headcase homolog (Drosophila)
chr15_+_79108911 0.584 ENSMUST00000040320.8
Micall1
microtubule associated monooxygenase, calponin and LIM domain containing -like 1
chr6_+_135198034 0.582 ENSMUST00000130612.1
8430419L09Rik
RIKEN cDNA 8430419L09 gene
chr4_+_119539652 0.579 ENSMUST00000044564.8
ENSMUST00000162267.1
ENSMUST00000106310.2
ENSMUST00000138845.2
Foxj3



forkhead box J3



chr11_-_116412965 0.560 ENSMUST00000100202.3
ENSMUST00000106398.2
Rnf157

ring finger protein 157

chr19_-_55099417 0.556 ENSMUST00000061856.5
Gpam
glycerol-3-phosphate acyltransferase, mitochondrial
chr11_+_93996082 0.552 ENSMUST00000041956.7
Spag9
sperm associated antigen 9
chr19_+_34550664 0.550 ENSMUST00000149829.1
ENSMUST00000102826.3
Ifit2

interferon-induced protein with tetratricopeptide repeats 2

chr11_+_115187481 0.547 ENSMUST00000100235.2
ENSMUST00000061450.6
Tmem104

transmembrane protein 104

chr2_+_28513105 0.544 ENSMUST00000135803.1
Ralgds
ral guanine nucleotide dissociation stimulator
chr19_-_5273080 0.542 ENSMUST00000025786.7
Pacs1
phosphofurin acidic cluster sorting protein 1
chr13_+_92611119 0.536 ENSMUST00000049488.7
Serinc5
serine incorporator 5
chr19_-_5510467 0.531 ENSMUST00000070172.4
Snx32
sorting nexin 32
chr13_-_54611274 0.530 ENSMUST00000049575.7
Cltb
clathrin, light polypeptide (Lcb)
chr2_-_58567157 0.529 ENSMUST00000056376.5
Acvr1
activin A receptor, type 1
chr17_-_57059795 0.522 ENSMUST00000040280.7
Slc25a23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr11_-_69369377 0.519 ENSMUST00000092971.6
ENSMUST00000108661.1
Chd3

chromodomain helicase DNA binding protein 3

chr2_-_28840274 0.517 ENSMUST00000037117.5
ENSMUST00000171404.1
Gtf3c4

general transcription factor IIIC, polypeptide 4

chr12_+_81026800 0.514 ENSMUST00000110347.2
ENSMUST00000021564.4
ENSMUST00000129362.1
Smoc1


SPARC related modular calcium binding 1


chr4_+_43578921 0.510 ENSMUST00000030190.8
Rgp1
RGP1 retrograde golgi transport homolog (S. cerevisiae)
chr6_+_51432663 0.509 ENSMUST00000005103.5
Nfe2l3
nuclear factor, erythroid derived 2, like 3
chr13_-_54611332 0.508 ENSMUST00000091609.4
Cltb
clathrin, light polypeptide (Lcb)
chr1_+_156558759 0.507 ENSMUST00000173929.1
Abl2
v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
chr11_+_75532099 0.504 ENSMUST00000169547.2
Slc43a2
solute carrier family 43, member 2
chr9_+_100643605 0.502 ENSMUST00000041418.6
Stag1
stromal antigen 1
chr7_-_31126945 0.502 ENSMUST00000098548.4
Scn1b
sodium channel, voltage-gated, type I, beta
chr2_+_28533355 0.502 ENSMUST00000113893.1
ENSMUST00000100241.3
Ralgds

ral guanine nucleotide dissociation stimulator

chr13_+_81711407 0.494 ENSMUST00000057598.5
Mblac2
metallo-beta-lactamase domain containing 2
chr13_+_54575008 0.493 ENSMUST00000026988.4
Arl10
ADP-ribosylation factor-like 10
chr5_-_137600650 0.490 ENSMUST00000111007.1
ENSMUST00000133705.1
Mospd3

motile sperm domain containing 3

chr9_-_108190352 0.485 ENSMUST00000035208.7
Bsn
bassoon
chr12_+_8674391 0.483 ENSMUST00000163569.1
ENSMUST00000169089.1
Pum2

pumilio 2 (Drosophila)

chr18_+_35965036 0.481 ENSMUST00000176873.1
ENSMUST00000177432.1
Psd2

pleckstrin and Sec7 domain containing 2

chr13_-_70637634 0.476 ENSMUST00000043493.5
BC018507
cDNA sequence BC018507
chr11_+_120721543 0.476 ENSMUST00000142229.1
Rac3
RAS-related C3 botulinum substrate 3
chr19_+_27217011 0.468 ENSMUST00000164746.1
ENSMUST00000172302.1
Vldlr

very low density lipoprotein receptor

chr17_-_45686899 0.459 ENSMUST00000156254.1
Tmem63b
transmembrane protein 63b
chrX_+_56346390 0.459 ENSMUST00000101560.3
Zfp449
zinc finger protein 449
chr2_-_160872985 0.455 ENSMUST00000109460.1
ENSMUST00000127201.1
Zhx3

zinc fingers and homeoboxes 3

chr4_+_133176336 0.452 ENSMUST00000105912.1
Wasf2
WAS protein family, member 2
chr11_+_53519920 0.446 ENSMUST00000147912.1
Sept8
septin 8
chr7_-_6696423 0.443 ENSMUST00000002336.8
Zim1
zinc finger, imprinted 1
chr12_-_76709997 0.443 ENSMUST00000166101.1
Sptb
spectrin beta, erythrocytic
chr2_-_160872829 0.441 ENSMUST00000176141.1
Zhx3
zinc fingers and homeoboxes 3
chr6_+_4601124 0.440 ENSMUST00000181734.1
ENSMUST00000141359.1
Casd1

CAS1 domain containing 1

chr9_+_109931774 0.436 ENSMUST00000169851.2
Map4
microtubule-associated protein 4
chrY_+_897782 0.434 ENSMUST00000055032.7
Kdm5d
lysine (K)-specific demethylase 5D
chr15_+_65787023 0.434 ENSMUST00000015146.9
ENSMUST00000173858.1
ENSMUST00000172756.1
ENSMUST00000174856.1
Efr3a



EFR3 homolog A (S. cerevisiae)



chr9_-_54661666 0.434 ENSMUST00000128624.1
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr11_+_53519871 0.434 ENSMUST00000120878.2
Sept8
septin 8
chr15_+_100870670 0.432 ENSMUST00000082209.6
Scn8a
sodium channel, voltage-gated, type VIII, alpha
chr9_+_15709715 0.431 ENSMUST00000115588.1
ENSMUST00000061568.7
Slc36a4

solute carrier family 36 (proton/amino acid symporter), member 4

chr1_+_87327044 0.431 ENSMUST00000173173.1
Gigyf2
GRB10 interacting GYF protein 2
chr15_-_100599983 0.431 ENSMUST00000073837.6
Pou6f1
POU domain, class 6, transcription factor 1
chr7_+_12881165 0.425 ENSMUST00000144578.1
Zfp128
zinc finger protein 128
chr9_-_27030010 0.422 ENSMUST00000034470.9
Vps26b
vacuolar protein sorting 26 homolog B (yeast)
chr18_-_20896078 0.422 ENSMUST00000025177.6
ENSMUST00000097658.1
Trappc8

trafficking protein particle complex 8

chr8_-_113848615 0.413 ENSMUST00000093113.4
Adamts18
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18
chr6_+_52714219 0.412 ENSMUST00000138040.1
ENSMUST00000129660.1
Tax1bp1

Tax1 (human T cell leukemia virus type I) binding protein 1

chr1_+_87327008 0.411 ENSMUST00000172794.1
ENSMUST00000164992.2
Gigyf2

GRB10 interacting GYF protein 2

chr7_-_57509995 0.411 ENSMUST00000068456.6
Gabra5
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5
chr13_-_59557230 0.411 ENSMUST00000165370.1
ENSMUST00000109830.2
ENSMUST00000022040.6
ENSMUST00000171606.1
ENSMUST00000167096.1
ENSMUST00000166585.1
Agtpbp1





ATP/GTP binding protein 1





chr17_+_7170101 0.410 ENSMUST00000024575.6
Rps6ka2
ribosomal protein S6 kinase, polypeptide 2
chr2_+_25428699 0.409 ENSMUST00000102919.3
Abca2
ATP-binding cassette, sub-family A (ABC1), member 2
chr1_-_52817643 0.407 ENSMUST00000027271.2
Inpp1
inositol polyphosphate-1-phosphatase
chr19_-_40612160 0.407 ENSMUST00000132452.1
ENSMUST00000135795.1
ENSMUST00000025981.8
Tctn3


tectonic family member 3


chr17_+_87107621 0.406 ENSMUST00000041369.6
Socs5
suppressor of cytokine signaling 5
chr16_-_91728701 0.406 ENSMUST00000114023.2
ENSMUST00000117644.1
Cryzl1

crystallin, zeta (quinone reductase)-like 1

chrX_+_73503074 0.405 ENSMUST00000114479.1
ENSMUST00000088429.1
ENSMUST00000033744.5
Atp2b3


ATPase, Ca++ transporting, plasma membrane 3


chr2_-_36104060 0.403 ENSMUST00000112961.3
ENSMUST00000112966.3
Lhx6

LIM homeobox protein 6

chr9_+_27030159 0.398 ENSMUST00000073127.7
ENSMUST00000086198.4
Ncapd3

non-SMC condensin II complex, subunit D3

chr10_-_79874211 0.397 ENSMUST00000167897.1
BC005764
cDNA sequence BC005764
chr3_+_95427575 0.396 ENSMUST00000181809.1
Gm4349
predicted gene 4349
chr4_+_85205417 0.395 ENSMUST00000030212.8
ENSMUST00000107189.1
ENSMUST00000107184.1
Sh3gl2


SH3-domain GRB2-like 2


chr12_-_4038905 0.393 ENSMUST00000111178.1
Efr3b
EFR3 homolog B (S. cerevisiae)
chr1_-_136260873 0.389 ENSMUST00000086395.5
Gpr25
G protein-coupled receptor 25
chr10_-_57532416 0.389 ENSMUST00000169122.1
Serinc1
serine incorporator 1
chr11_+_72796254 0.384 ENSMUST00000069395.5
Zzef1
zinc finger, ZZ-type with EF hand domain 1
chr7_+_28180272 0.384 ENSMUST00000173223.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr1_+_139422196 0.384 ENSMUST00000039867.7
Zbtb41
zinc finger and BTB domain containing 41 homolog
chr6_-_137649211 0.383 ENSMUST00000134630.1
ENSMUST00000058210.6
ENSMUST00000111878.1
Eps8


epidermal growth factor receptor pathway substrate 8


chr19_+_27217357 0.383 ENSMUST00000047645.6
ENSMUST00000167487.1
Vldlr

very low density lipoprotein receptor

chr11_+_72796164 0.381 ENSMUST00000172220.1
Zzef1
zinc finger, ZZ-type with EF hand domain 1
chrX_+_71364745 0.377 ENSMUST00000114601.1
ENSMUST00000146213.1
ENSMUST00000015358.1
Mtmr1


myotubularin related protein 1


chr11_+_68691906 0.377 ENSMUST00000102611.3
Myh10
myosin, heavy polypeptide 10, non-muscle
chr18_-_80986578 0.377 ENSMUST00000057950.7
Sall3
sal-like 3 (Drosophila)
chr8_+_20550331 0.375 ENSMUST00000178451.1
Gm21092
predicted gene, 21092
chr7_+_16130285 0.370 ENSMUST00000168693.1
Slc8a2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr18_+_63708689 0.368 ENSMUST00000072726.5
Wdr7
WD repeat domain 7
chr1_+_37299882 0.364 ENSMUST00000136846.1
ENSMUST00000027287.4
ENSMUST00000132401.1
Inpp4a


inositol polyphosphate-4-phosphatase, type I


chr1_-_165460430 0.364 ENSMUST00000027856.7
Dcaf6
DDB1 and CUL4 associated factor 6
chr19_-_29047847 0.364 ENSMUST00000025696.4
Ak3
adenylate kinase 3
chr6_+_135197977 0.364 ENSMUST00000111915.1
ENSMUST00000111916.1
8430419L09Rik

RIKEN cDNA 8430419L09 gene

chr11_-_118248507 0.364 ENSMUST00000017276.7
Cyth1
cytohesin 1
chr19_-_29805507 0.361 ENSMUST00000175726.1
9930021J03Rik
RIKEN cDNA 9930021J03 gene
chr1_-_52817503 0.361 ENSMUST00000162576.1
Inpp1
inositol polyphosphate-1-phosphatase
chr1_-_153332724 0.360 ENSMUST00000027752.8
Lamc1
laminin, gamma 1
chr17_-_24689901 0.356 ENSMUST00000007236.4
Syngr3
synaptogyrin 3
chr1_-_93101854 0.356 ENSMUST00000171796.1
ENSMUST00000171556.1
Kif1a

kinesin family member 1A

chr4_+_119539716 0.352 ENSMUST00000137560.1
Foxj3
forkhead box J3
chr11_-_71004387 0.350 ENSMUST00000124464.1
ENSMUST00000108527.1
Dhx33

DEAH (Asp-Glu-Ala-His) box polypeptide 33

chr1_-_155417283 0.350 ENSMUST00000027741.5
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr11_+_68692097 0.350 ENSMUST00000018887.8
Myh10
myosin, heavy polypeptide 10, non-muscle
chr11_-_35798884 0.346 ENSMUST00000160726.2
Fbll1
fibrillarin-like 1
chr9_-_15045378 0.344 ENSMUST00000164273.1
Panx1
pannexin 1
chr13_-_49147931 0.343 ENSMUST00000162581.1
ENSMUST00000110097.2
ENSMUST00000049265.8
ENSMUST00000035538.6
ENSMUST00000110096.1
ENSMUST00000091623.3
Wnk2





WNK lysine deficient protein kinase 2





chr9_+_100643448 0.343 ENSMUST00000146312.1
ENSMUST00000129269.1
Stag1

stromal antigen 1

chr12_-_72070991 0.342 ENSMUST00000050649.4
Gpr135
G protein-coupled receptor 135
chr16_+_17561885 0.342 ENSMUST00000171002.1
ENSMUST00000023441.4
P2rx6

purinergic receptor P2X, ligand-gated ion channel, 6

chr11_-_85139939 0.336 ENSMUST00000108075.2
Usp32
ubiquitin specific peptidase 32
chr4_+_43059028 0.335 ENSMUST00000163653.1
ENSMUST00000107952.2
ENSMUST00000107953.2
Unc13b


unc-13 homolog B (C. elegans)


chr19_-_29805989 0.335 ENSMUST00000177155.1
ENSMUST00000059484.7
9930021J03Rik

RIKEN cDNA 9930021J03 gene

chr7_+_28180226 0.335 ENSMUST00000172467.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr8_+_109868586 0.334 ENSMUST00000179721.1
ENSMUST00000034175.4
Phlpp2

PH domain and leucine rich repeat protein phosphatase 2

chr11_+_120721452 0.333 ENSMUST00000018156.5
Rac3
RAS-related C3 botulinum substrate 3
chr11_+_117654211 0.331 ENSMUST00000026658.6
Tnrc6c
trinucleotide repeat containing 6C
chr4_-_155774563 0.329 ENSMUST00000042196.3
Vwa1
von Willebrand factor A domain containing 1
chrX_+_134059315 0.329 ENSMUST00000144483.1
Cstf2
cleavage stimulation factor, 3' pre-RNA subunit 2
chr17_+_25188380 0.325 ENSMUST00000039734.5
Unkl
unkempt-like (Drosophila)
chr1_-_30949756 0.325 ENSMUST00000076587.3
ENSMUST00000027232.7
Ptp4a1

protein tyrosine phosphatase 4a1

chr4_-_151108454 0.324 ENSMUST00000105670.1
Camta1
calmodulin binding transcription activator 1
chr16_+_10545339 0.323 ENSMUST00000066345.7
ENSMUST00000115824.3
ENSMUST00000155633.1
Clec16a


C-type lectin domain family 16, member A


chr4_+_31964081 0.323 ENSMUST00000037607.4
ENSMUST00000080933.6
ENSMUST00000108183.1
ENSMUST00000108184.2
Map3k7



mitogen-activated protein kinase kinase kinase 7



chr2_+_31572775 0.319 ENSMUST00000137889.1
Fubp3
far upstream element (FUSE) binding protein 3
chr1_+_156558844 0.311 ENSMUST00000166172.2
ENSMUST00000027888.6
Abl2

v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)

chr19_+_40612392 0.309 ENSMUST00000134063.1
Entpd1
ectonucleoside triphosphate diphosphohydrolase 1
chr2_-_160872552 0.305 ENSMUST00000103111.2
Zhx3
zinc fingers and homeoboxes 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0070650 actin filament bundle distribution(GO:0070650)
0.4 1.3 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.4 1.5 GO:0060912 cardiac cell fate specification(GO:0060912)
0.4 1.5 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.3 1.0 GO:1900673 olefin metabolic process(GO:1900673)
0.3 1.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.3 1.8 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.3 1.8 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.2 0.7 GO:1902022 L-lysine transport(GO:1902022)
0.2 0.7 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.2 0.6 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.2 0.4 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.2 1.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.2 1.0 GO:1990034 calcium ion export from cell(GO:1990034)
0.2 1.8 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.2 0.5 GO:0003289 endocardial cushion fusion(GO:0003274) atrial septum primum morphogenesis(GO:0003289)
0.2 0.5 GO:0097274 urea homeostasis(GO:0097274)
0.2 0.5 GO:0050975 sensory perception of touch(GO:0050975)
0.2 0.3 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) interleukin-1 alpha secretion(GO:0050703)
0.2 0.9 GO:0034436 glycoprotein transport(GO:0034436)
0.2 0.8 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.2 0.5 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.2 0.5 GO:0008355 olfactory learning(GO:0008355)
0.2 0.5 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.2 0.9 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.2 2.8 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.2 1.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.9 GO:0009405 pathogenesis(GO:0009405)
0.1 1.2 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.1 1.5 GO:0070970 interleukin-2 secretion(GO:0070970)
0.1 1.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 0.6 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.1 1.0 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 1.4 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 3.0 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.3 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1 0.8 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.7 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.1 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.4 GO:0051012 microtubule sliding(GO:0051012)
0.1 1.0 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.4 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 2.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.3 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.1 0.6 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.6 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.3 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.1 0.3 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 0.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 0.3 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.1 0.2 GO:0060268 negative regulation of respiratory burst(GO:0060268)
0.1 0.4 GO:0015808 L-alanine transport(GO:0015808)
0.1 0.2 GO:0071336 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 0.8 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 0.2 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 0.4 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 0.4 GO:0030242 pexophagy(GO:0030242)
0.1 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 1.6 GO:0046856 phospholipid dephosphorylation(GO:0046839) phosphatidylinositol dephosphorylation(GO:0046856)
0.1 0.4 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 0.4 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.8 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 0.5 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 0.5 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.1 GO:2000331 regulation of terminal button organization(GO:2000331)
0.1 0.3 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.1 0.5 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 0.3 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.9 GO:0036010 protein localization to endosome(GO:0036010)
0.0 1.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.5 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.1 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.0 0.1 GO:0014891 striated muscle atrophy(GO:0014891)
0.0 0.2 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 1.1 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.5 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.1 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.0 0.3 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 2.2 GO:0015807 L-amino acid transport(GO:0015807)
0.0 0.2 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.0 1.0 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.2 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.2 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.6 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.1 GO:0006566 threonine metabolic process(GO:0006566)
0.0 0.1 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.5 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.7 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.4 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.5 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.7 GO:0042092 type 2 immune response(GO:0042092)
0.0 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.4 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.1 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.2 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.4 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.2 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.1 GO:0007403 glial cell fate determination(GO:0007403)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:0006817 phosphate ion transport(GO:0006817)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.5 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.0 0.2 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.7 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.1 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 1.3 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.2 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.4 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.6 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.3 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.1 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.3 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.1 GO:0034382 chylomicron remnant clearance(GO:0034382) positive regulation of lipoprotein lipase activity(GO:0051006) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.0 GO:0030070 insulin processing(GO:0030070)
0.0 1.0 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 0.1 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0051262 protein tetramerization(GO:0051262)
0.0 0.1 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.1 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.4 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.2 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.5 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.1 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.0 GO:0035672 transepithelial chloride transport(GO:0030321) oligopeptide transmembrane transport(GO:0035672)
0.0 0.3 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.2 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 0.4 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.2 GO:0033198 response to ATP(GO:0033198)
0.0 0.3 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.1 GO:0006544 glycine metabolic process(GO:0006544)
0.0 0.1 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.1 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.4 GO:0002209 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.3 1.1 GO:0032280 symmetric synapse(GO:0032280)
0.3 1.5 GO:0097513 myosin II filament(GO:0097513)
0.3 1.0 GO:0044307 dendritic branch(GO:0044307)
0.2 0.5 GO:0048179 activin receptor complex(GO:0048179)
0.2 2.0 GO:0016600 flotillin complex(GO:0016600)
0.2 0.5 GO:0071920 cleavage body(GO:0071920)
0.2 0.5 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.1 0.4 GO:0000799 nuclear condensin complex(GO:0000799) germinal vesicle(GO:0042585)
0.1 1.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.8 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.4 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.1 1.0 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 0.5 GO:0008091 spectrin(GO:0008091)
0.1 0.4 GO:0001533 cornified envelope(GO:0001533)
0.1 1.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.9 GO:0030139 endocytic vesicle(GO:0030139)
0.1 1.1 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.5 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.3 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.3 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.2 GO:0048786 presynaptic active zone(GO:0048786)
0.1 1.0 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.6 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 0.3 GO:0044305 calyx of Held(GO:0044305)
0.1 0.3 GO:0070820 tertiary granule(GO:0070820)
0.0 0.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.5 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.7 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.8 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0097422 tubular endosome(GO:0097422)
0.0 0.8 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.7 GO:0035253 ciliary rootlet(GO:0035253)
0.0 2.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.2 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.6 GO:0030118 clathrin coat(GO:0030118)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0005605 basal lamina(GO:0005605)
0.0 0.4 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.0 GO:0034679 integrin alpha9-beta1 complex(GO:0034679)
0.0 0.5 GO:0030904 retromer complex(GO:0030904)
0.0 0.8 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.8 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 2.7 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 1.6 GO:0005903 brush border(GO:0005903)
0.0 0.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 3.2 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.4 GO:0031901 early endosome membrane(GO:0031901)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.3 0.9 GO:0034437 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
0.2 0.7 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.2 0.7 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.2 1.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 0.8 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.2 0.7 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.2 1.0 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.2 0.6 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.4 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 0.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.9 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.4 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.4 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.5 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.1 1.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 2.0 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.4 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 1.8 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.3 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.1 1.0 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.0 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 3.4 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.5 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 1.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 2.2 GO:0070064 proline-rich region binding(GO:0070064)
0.1 2.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.6 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.2 GO:0032139 guanine/thymine mispair binding(GO:0032137) dinucleotide insertion or deletion binding(GO:0032139) single guanine insertion binding(GO:0032142)
0.1 0.5 GO:0086006 sodium channel inhibitor activity(GO:0019871) voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 1.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.1 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 0.3 GO:0035473 lipase binding(GO:0035473)
0.1 0.3 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903)
0.1 0.4 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.1 1.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.3 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.1 0.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.3 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 1.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.2 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.1 0.5 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 0.4 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.7 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 1.2 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.4 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.2 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 1.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.8 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.3 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.6 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.4 GO:0000182 rDNA binding(GO:0000182)
0.0 0.3 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.7 GO:0008483 transaminase activity(GO:0008483)
0.0 0.1 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215) organophosphate ester transmembrane transporter activity(GO:0015605)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.3 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 1.1 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:2001069 glycogen binding(GO:2001069)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.5 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.2 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.1 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.0 0.0 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.7 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.0 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.4 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 PID_EPO_PATHWAY EPO signaling pathway
0.1 3.3 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 0.4 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.5 PID_ALK2_PATHWAY ALK2 signaling events
0.0 1.5 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.7 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.8 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 1.0 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.5 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 1.1 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.0 0.3 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.8 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 2.3 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.0 1.2 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.4 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 0.5 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.1 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 0.5 PID_INSULIN_PATHWAY Insulin Pathway
0.0 0.2 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.3 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.4 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.4 PID_SHP2_PATHWAY SHP2 signaling
0.0 0.1 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.3 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 0.7 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.2 2.0 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.8 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.1 3.1 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.2 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.1 2.9 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.1 1.0 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 1.0 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 0.7 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.9 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.1 REACTOME_MRNA_CAPPING Genes involved in mRNA Capping
0.0 0.5 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.5 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS Genes involved in Prolonged ERK activation events
0.0 1.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.6 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.2 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.5 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.9 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.6 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.6 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 0.8 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.4 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.6 REACTOME_KINESINS Genes involved in Kinesins
0.0 1.5 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.2 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.4 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.0 0.6 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.2 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.6 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.2 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.1 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.4 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.1 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling