Motif ID: Zfp105

Z-value: 0.272


Transcription factors associated with Zfp105:

Gene SymbolEntrez IDGene Name
Zfp105 ENSMUSG00000057895.5 Zfp105

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp105mm10_v2_chr9_+_122923050_122923099-0.292.5e-01Click!


Activity profile for motif Zfp105.

activity profile for motif Zfp105


Sorted Z-values histogram for motif Zfp105

Sorted Z-values for motif Zfp105



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp105

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_84773381 0.293 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr8_+_128359065 0.253 ENSMUST00000026917.8
 Nrp1
neuropilin 1
chr4_+_144892813 0.171 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr8_-_109251698 0.170 ENSMUST00000079189.3
 4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr10_-_96409038 0.153 ENSMUST00000179683.1
 Gm20091
predicted gene, 20091
chr9_-_78378725 0.133 ENSMUST00000034900.7
 Ooep
oocyte expressed protein
chr6_-_142964404 0.132 ENSMUST00000032421.3
 St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr18_+_35770318 0.132 ENSMUST00000165299.1
 Gm16490
predicted gene 16490
chr18_+_37484955 0.121 ENSMUST00000053856.4
 Pcdhb17
protocadherin beta 17
chr15_-_81843699 0.110 ENSMUST00000092020.2
 Gm8444
predicted gene 8444
chr10_+_128267997 0.097 ENSMUST00000050901.2
 Apof
apolipoprotein F
chr15_+_102460076 0.095 ENSMUST00000164688.1
 Prr13
proline rich 13
chr15_+_85510812 0.092 ENSMUST00000079690.2
 Gm4825
predicted pseudogene 4825
chr5_+_136953246 0.087 ENSMUST00000111094.1
ENSMUST00000111097.1
 Fis1

fission 1 (mitochondrial outer membrane) homolog (yeast)

chr5_+_19907502 0.075 ENSMUST00000101558.3
 Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr8_-_57487801 0.074 ENSMUST00000034022.3
 Sap30
sin3 associated polypeptide
chr1_+_156366037 0.074 ENSMUST00000102782.3
 Gm2000
predicted gene 2000
chr10_-_128549102 0.071 ENSMUST00000176906.1
 Rpl41
ribosomal protein L41
chr11_-_101466222 0.067 ENSMUST00000040430.7
 Vat1
vesicle amine transport protein 1 homolog (T californica)
chr15_+_99006056 0.067 ENSMUST00000079818.3
 Gm8973
predicted gene 8973
chr12_-_90738438 0.066 ENSMUST00000082432.3
 Dio2
deiodinase, iodothyronine, type II
chr9_-_19928282 0.065 ENSMUST00000082002.5
 Gm7808
predicted pseudogene 7808
chr6_-_99632376 0.060 ENSMUST00000176255.1
 Gm20696
predicted gene 20696
chr15_+_37233036 0.055 ENSMUST00000161405.1
ENSMUST00000022895.8
ENSMUST00000161532.1
 Grhl2


grainyhead-like 2 (Drosophila)


chr18_+_69344503 0.053 ENSMUST00000114985.3
 Tcf4
transcription factor 4
chr15_+_78983041 0.052 ENSMUST00000109687.1
ENSMUST00000109688.1
ENSMUST00000130663.2
 Triobp


TRIO and F-actin binding protein


chr18_+_30272747 0.052 ENSMUST00000115812.3
ENSMUST00000115811.1
ENSMUST00000091978.5
 Pik3c3


phosphoinositide-3-kinase, class 3


chr17_+_6079928 0.051 ENSMUST00000100955.2
 Gtf2h5
general transcription factor IIH, polypeptide 5
chr2_+_107290590 0.047 ENSMUST00000037012.2
 Kcna4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr8_-_106573461 0.045 ENSMUST00000073722.5
 Gm10073
predicted pseudogene 10073
chr4_+_11704439 0.045 ENSMUST00000108304.2
 Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr1_-_184732616 0.040 ENSMUST00000048572.6
 Hlx
H2.0-like homeobox
chr5_+_138363719 0.040 ENSMUST00000100526.2
 Gm10874
predicted gene 10874
chr7_+_66109474 0.039 ENSMUST00000036372.6
 Chsy1
chondroitin sulfate synthase 1
chr5_-_149053038 0.033 ENSMUST00000085546.6
 Hmgb1
high mobility group box 1
chr6_-_99435345 0.027 ENSMUST00000113322.2
ENSMUST00000176850.1
ENSMUST00000176632.1
 Foxp1


forkhead box P1


chr4_-_3973581 0.025 ENSMUST00000089430.4
 Gm11808
predicted gene 11808
chr8_+_93810832 0.023 ENSMUST00000034198.8
ENSMUST00000125716.1
 Gnao1

guanine nucleotide binding protein, alpha O

chr6_-_99028874 0.020 ENSMUST00000154163.2
 Foxp1
forkhead box P1
chr4_+_105157339 0.019 ENSMUST00000064139.7
 Ppap2b
phosphatidic acid phosphatase type 2B
chr7_-_116084635 0.019 ENSMUST00000111755.3
 Gm4353
predicted gene 4353
chr13_-_21501418 0.017 ENSMUST00000044043.2
 Gm11273
predicted gene 11273
chr6_+_29859374 0.012 ENSMUST00000115238.3
 Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr2_-_91931774 0.011 ENSMUST00000069423.6
 Mdk
midkine
chr14_+_11227511 0.010 ENSMUST00000080237.3
 Rpl21-ps4
ribosomal protein L21, pseudogene 4
chr12_-_51971289 0.009 ENSMUST00000040583.5
 Heatr5a
HEAT repeat containing 5A
chr11_-_100411874 0.008 ENSMUST00000141840.1
 Leprel4
leprecan-like 4
chr8_-_64205970 0.005 ENSMUST00000066166.4
 Tll1
tolloid-like
chr18_+_35829798 0.004 ENSMUST00000060722.6
 Cxxc5
CXXC finger 5
chr11_-_102316691 0.003 ENSMUST00000107115.1
ENSMUST00000128016.1
 Ubtf

upstream binding transcription factor, RNA polymerase I

chr5_+_17574268 0.002 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr13_-_67609667 0.001 ENSMUST00000012873.8
 AA987161
expressed sequence AA987161
chr9_+_78175898 0.000 ENSMUST00000180974.1
 C920006O11Rik
RIKEN cDNA C920006O11 gene
chr11_-_22286795 0.000 ENSMUST00000109563.2
ENSMUST00000180360.1
 Ehbp1

EH domain binding protein 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0035441 vestibulocochlear nerve structural organization(GO:0021649) cell migration involved in vasculogenesis(GO:0035441) neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) ganglion morphogenesis(GO:0061552) positive regulation of retinal ganglion cell axon guidance(GO:1902336) dorsal root ganglion morphogenesis(GO:1904835)
0.0 0.1 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.0 0.1 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.2 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.1 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.0 0.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.0 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.0 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions