Motif ID: Zfp128

Z-value: 0.280


Transcription factors associated with Zfp128:

Gene SymbolEntrez IDGene Name
Zfp128 ENSMUSG00000060397.6 Zfp128

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp128mm10_v2_chr7_+_12881165_128812040.609.2e-03Click!


Activity profile for motif Zfp128.

activity profile for motif Zfp128


Sorted Z-values histogram for motif Zfp128

Sorted Z-values for motif Zfp128



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp128

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_195092242 0.783 ENSMUST00000162650.1
ENSMUST00000160817.1
ENSMUST00000162614.1
ENSMUST00000016637.6
 Cd46



CD46 antigen, complement regulatory protein



chr15_-_84065329 0.623 ENSMUST00000156187.1
 Efcab6
EF-hand calcium binding domain 6
chr8_-_45975224 0.588 ENSMUST00000095323.1
ENSMUST00000098786.2
 1700029J07Rik

RIKEN cDNA 1700029J07 gene

chr14_-_105896819 0.547 ENSMUST00000022709.4
 Spry2
sprouty homolog 2 (Drosophila)
chr10_-_109010955 0.529 ENSMUST00000105276.1
ENSMUST00000064054.7
 Syt1

synaptotagmin I

chr6_-_118562226 0.516 ENSMUST00000112830.1
 Ankrd26
ankyrin repeat domain 26
chr7_-_79386943 0.410 ENSMUST00000053718.8
ENSMUST00000179243.1
 Rlbp1

retinaldehyde binding protein 1

chr3_+_146220955 0.398 ENSMUST00000039164.2
 Lpar3
lysophosphatidic acid receptor 3
chr7_+_45526330 0.362 ENSMUST00000120985.1
ENSMUST00000051810.8
 Plekha4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

chr7_+_24112314 0.352 ENSMUST00000120006.1
ENSMUST00000005413.3
 Zfp112

zinc finger protein 112

chr2_-_30124454 0.311 ENSMUST00000044751.8
 Zer1
zyg-11 related, cell cycle regulator
chr2_-_30124529 0.263 ENSMUST00000113677.1
 Zer1
zyg-11 related, cell cycle regulator
chr3_+_103576081 0.253 ENSMUST00000183637.1
ENSMUST00000117221.2
ENSMUST00000118117.1
ENSMUST00000118563.2
 Syt6



synaptotagmin VI



chr15_+_76246747 0.252 ENSMUST00000023225.6
 Grina
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr2_+_71055731 0.233 ENSMUST00000154704.1
ENSMUST00000135357.1
ENSMUST00000064141.5
ENSMUST00000112159.2
ENSMUST00000102701.3
 Dcaf17




DDB1 and CUL4 associated factor 17




chr5_-_147725988 0.223 ENSMUST00000110529.1
ENSMUST00000031652.3
ENSMUST00000031653.5
 Flt1


FMS-like tyrosine kinase 1


chr5_+_144545883 0.208 ENSMUST00000071782.6
 Nptx2
neuronal pentraxin 2
chr8_-_41133697 0.205 ENSMUST00000155055.1
ENSMUST00000059115.6
ENSMUST00000145860.1
 Mtus1


mitochondrial tumor suppressor 1


chr4_+_126556994 0.194 ENSMUST00000147675.1
 Clspn
claspin
chr11_+_32300069 0.187 ENSMUST00000020535.1
 Hbq1a
hemoglobin, theta 1A
chr9_+_3335470 0.183 ENSMUST00000053407.5
 Alkbh8
alkB, alkylation repair homolog 8 (E. coli)
chr16_-_14159232 0.182 ENSMUST00000090300.4
 Marf1
meiosis arrest female 1
chr13_-_66933014 0.179 ENSMUST00000173773.1
 Mterfd1
MTERF domain containing 1
chr9_-_59353430 0.153 ENSMUST00000026265.6
 Bbs4
Bardet-Biedl syndrome 4 (human)
chr13_-_66932904 0.142 ENSMUST00000172597.1
 Mterfd1
MTERF domain containing 1
chr3_-_79567771 0.142 ENSMUST00000133154.1
 Fnip2
folliculin interacting protein 2
chr7_-_44929410 0.126 ENSMUST00000107857.3
ENSMUST00000085399.6
ENSMUST00000167930.1
ENSMUST00000166972.1
 Ap2a1



adaptor-related protein complex 2, alpha 1 subunit



chr18_+_74065102 0.126 ENSMUST00000066583.1
 Gm9925
predicted gene 9925
chr13_+_66932802 0.124 ENSMUST00000021990.3
 Ptdss1
phosphatidylserine synthase 1
chr3_-_79567679 0.078 ENSMUST00000076136.4
 Fnip2
folliculin interacting protein 2
chr6_-_113501818 0.075 ENSMUST00000101059.1
 Prrt3
proline-rich transmembrane protein 3
chr1_-_190170671 0.068 ENSMUST00000175916.1
 Prox1
prospero-related homeobox 1
chr17_-_26244203 0.052 ENSMUST00000114988.1
 Itfg3
integrin alpha FG-GAP repeat containing 3
chr14_+_54894133 0.050 ENSMUST00000116476.2
ENSMUST00000022808.7
ENSMUST00000150975.1
 Pabpn1


poly(A) binding protein, nuclear 1


chr2_-_71055534 0.049 ENSMUST00000090849.5
ENSMUST00000100037.2
ENSMUST00000112186.2
 Mettl8


methyltransferase like 8


chr13_-_59769751 0.049 ENSMUST00000057115.6
 Isca1
iron-sulfur cluster assembly 1 homolog (S. cerevisiae)
chr17_-_26244118 0.042 ENSMUST00000118487.1
 Itfg3
integrin alpha FG-GAP repeat containing 3
chr13_-_66933080 0.031 ENSMUST00000021991.4
 Mterfd1
MTERF domain containing 1
chr4_+_126556935 0.030 ENSMUST00000048391.8
 Clspn
claspin
chr15_+_76879232 0.004 ENSMUST00000023179.5
 Zfp7
zinc finger protein 7
chr5_-_138171216 0.001 ENSMUST00000147920.1
 Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0043379 memory T cell differentiation(GO:0043379)
0.1 0.5 GO:0060437 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) lung growth(GO:0060437)
0.1 0.3 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 0.5 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.2 GO:1903546 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.2 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.5 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.0 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.5 GO:0031045 dense core granule(GO:0031045)
0.0 0.4 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.2 GO:0034464 BBSome(GO:0034464)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.4 GO:0019841 retinol binding(GO:0019841)
0.1 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.8 GO:0001848 complement binding(GO:0001848)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.1 0.5 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.5 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions