Motif ID: Zfp148

Z-value: 1.388


Transcription factors associated with Zfp148:

Gene SymbolEntrez IDGene Name
Zfp148 ENSMUSG00000022811.10 Zfp148

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp148mm10_v2_chr16_+_33380765_333807870.831.8e-05Click!


Activity profile for motif Zfp148.

activity profile for motif Zfp148


Sorted Z-values histogram for motif Zfp148

Sorted Z-values for motif Zfp148



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp148

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_98032983 12.544 ENSMUST00000162295.1
 Clstn2
calsyntenin 2
chr6_+_103510874 8.339 ENSMUST00000066905.6
 Chl1
cell adhesion molecule with homology to L1CAM
chr8_+_70493156 8.055 ENSMUST00000008032.7
 Crlf1
cytokine receptor-like factor 1
chr9_-_40455670 7.270 ENSMUST00000165104.1
ENSMUST00000045682.5
 Gramd1b

GRAM domain containing 1B

chr10_+_13966268 6.292 ENSMUST00000015645.4
 Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr5_+_17574726 4.735 ENSMUST00000169603.1
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr5_+_17574268 4.436 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr4_-_138396438 4.211 ENSMUST00000105032.2
 Fam43b
family with sequence similarity 43, member B
chr10_+_106470281 4.095 ENSMUST00000029404.9
ENSMUST00000169303.1
 Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr9_-_29411736 3.862 ENSMUST00000115236.1
 Ntm
neurotrimin
chr11_-_102897123 3.683 ENSMUST00000067444.3
 Gfap
glial fibrillary acidic protein
chr9_-_29412204 3.388 ENSMUST00000115237.1
 Ntm
neurotrimin
chr4_-_133498538 3.111 ENSMUST00000125541.1
 Trnp1
TMF1-regulated nuclear protein 1
chr2_-_104409992 2.926 ENSMUST00000149466.1
ENSMUST00000139015.1
 D430041D05Rik

RIKEN cDNA D430041D05 gene

chr7_-_27396542 2.894 ENSMUST00000108363.1
 Sptbn4
spectrin beta, non-erythrocytic 4
chr10_+_127078886 2.885 ENSMUST00000039259.6
 Agap2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr3_-_127499095 2.785 ENSMUST00000182594.1
 Ank2
ankyrin 2, brain
chr1_-_134235420 2.770 ENSMUST00000038191.6
ENSMUST00000086465.4
 Adora1

adenosine A1 receptor

chr11_+_115163333 2.732 ENSMUST00000021077.3
 Slc9a3r1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr2_+_107290590 2.718 ENSMUST00000037012.2
 Kcna4
potassium voltage-gated channel, shaker-related subfamily, member 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 137 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 21.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.5 9.2 GO:0003350 pulmonary myocardium development(GO:0003350)
1.3 8.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.8 5.4 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.0 4.8 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.4 4.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 4.2 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.6 3.9 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.8 3.8 GO:0060178 regulation of exocyst localization(GO:0060178)
0.1 3.1 GO:0021696 cerebellar cortex morphogenesis(GO:0021696)
1.0 3.0 GO:1904978 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
0.2 3.0 GO:1990403 embryonic brain development(GO:1990403)
0.5 2.9 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.3 2.9 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.9 2.8 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.3 2.8 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.9 2.7 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.1 2.6 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.4 2.5 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 2.5 GO:0009404 toxin metabolic process(GO:0009404)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 61 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 16.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 11.1 GO:0030425 dendrite(GO:0030425)
0.1 10.8 GO:0031225 anchored component of membrane(GO:0031225)
2.7 8.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.3 5.5 GO:0032279 asymmetric synapse(GO:0032279)
1.3 5.4 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 4.2 GO:0030118 clathrin coat(GO:0030118)
0.1 3.2 GO:0031901 early endosome membrane(GO:0031901)
0.1 3.0 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 3.0 GO:0035869 ciliary transition zone(GO:0035869)
0.0 3.0 GO:0031594 neuromuscular junction(GO:0031594)
0.5 2.9 GO:0008091 spectrin(GO:0008091)
0.1 2.8 GO:0031430 M band(GO:0031430)
0.2 2.7 GO:0032426 stereocilium tip(GO:0032426)
0.1 2.7 GO:0016235 aggresome(GO:0016235)
0.1 2.3 GO:0000145 exocyst(GO:0000145)
0.1 1.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.9 GO:0008021 synaptic vesicle(GO:0008021)
0.5 1.8 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1 1.8 GO:0008385 IkappaB kinase complex(GO:0008385)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 99 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 10.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 8.4 GO:0030695 GTPase regulator activity(GO:0030695)
1.2 8.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 8.1 GO:0005509 calcium ion binding(GO:0005509)
0.1 7.9 GO:0002020 protease binding(GO:0002020)
0.1 6.4 GO:0030507 spectrin binding(GO:0030507)
0.0 6.0 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.0 4.3 GO:0051082 unfolded protein binding(GO:0051082)
0.1 4.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.4 3.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.4 3.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.6 3.0 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 3.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 2.9 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.4 2.8 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795)
0.1 2.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.2 2.7 GO:0017081 chloride channel regulator activity(GO:0017081)
0.2 2.7 GO:0030955 potassium ion binding(GO:0030955)
0.2 2.6 GO:0044548 S100 protein binding(GO:0044548)
0.8 2.5 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.1 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 4.9 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 4.0 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.1 3.5 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 2.5 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 1.8 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 1.7 PID_INSULIN_PATHWAY Insulin Pathway
0.0 1.6 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 1.5 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 1.5 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.5 PID_SHP2_PATHWAY SHP2 signaling
0.0 1.2 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.9 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.9 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.9 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.9 PID_P73PATHWAY p73 transcription factor network
0.0 0.8 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 0.7 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.6 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.0 0.6 PID_ARF6_PATHWAY Arf6 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.3 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 4.9 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.2 4.0 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 3.9 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 3.6 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 3.1 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.2 2.8 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 2.5 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 2.1 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.3 2.0 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 1.8 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 1.5 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.2 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 1.2 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.1 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.1 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.0 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 0.9 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.9 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 0.7 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins