Motif ID: Zfp263

Z-value: 0.642


Transcription factors associated with Zfp263:

Gene SymbolEntrez IDGene Name
Zfp263 ENSMUSG00000022529.5 Zfp263

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp263mm10_v2_chr16_+_3744089_37441450.437.2e-02Click!


Activity profile for motif Zfp263.

activity profile for motif Zfp263


Sorted Z-values histogram for motif Zfp263

Sorted Z-values for motif Zfp263



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp263

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_34861200 2.335 ENSMUST00000165033.1
Egr1
early growth response 1
chr5_-_150594493 1.266 ENSMUST00000016279.7
N4bp2l1
NEDD4 binding protein 2-like 1
chr4_+_104367549 0.911 ENSMUST00000106830.2
Dab1
disabled 1
chr8_-_105966038 0.846 ENSMUST00000116429.2
ENSMUST00000034370.9
Slc12a4

solute carrier family 12, member 4

chr9_-_40531362 0.843 ENSMUST00000119373.1
Gramd1b
GRAM domain containing 1B
chr6_-_29507946 0.839 ENSMUST00000101614.3
ENSMUST00000078112.6
Kcp

kielin/chordin-like protein

chrX_+_136822781 0.814 ENSMUST00000113085.1
Plp1
proteolipid protein (myelin) 1
chr17_-_90455872 0.779 ENSMUST00000174337.1
ENSMUST00000172466.1
Nrxn1

neurexin I

chr1_-_134332928 0.778 ENSMUST00000168515.1
Ppfia4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr16_-_23988852 0.754 ENSMUST00000023151.5
Bcl6
B cell leukemia/lymphoma 6
chrX_+_136822671 0.748 ENSMUST00000033800.6
Plp1
proteolipid protein (myelin) 1
chr7_+_49246131 0.738 ENSMUST00000064395.6
Nav2
neuron navigator 2
chr16_+_11984581 0.737 ENSMUST00000170672.2
ENSMUST00000023138.7
Shisa9

shisa homolog 9 (Xenopus laevis)

chr9_+_27790947 0.732 ENSMUST00000115243.2
Opcml
opioid binding protein/cell adhesion molecule-like
chr9_+_37367354 0.731 ENSMUST00000051839.7
Hepacam
hepatocyte cell adhesion molecule
chr10_+_13966268 0.729 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr9_-_58313189 0.705 ENSMUST00000061799.8
Loxl1
lysyl oxidase-like 1
chrX_-_94123087 0.693 ENSMUST00000113925.1
Zfx
zinc finger protein X-linked
chr1_-_173942445 0.671 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr13_-_45964964 0.663 ENSMUST00000180110.1
ENSMUST00000091628.3
ENSMUST00000167708.2
Atxn1


ataxin 1



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 175 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 2.6 GO:0072223 metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.1 1.6 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.4 1.4 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.0 1.4 GO:0008542 visual learning(GO:0008542)
0.1 1.3 GO:0060746 parental behavior(GO:0060746)
0.2 1.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.2 1.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.3 0.9 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.3 0.9 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.2 0.9 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.3 0.8 GO:0043379 memory T cell differentiation(GO:0043379) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.2 0.8 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.2 0.8 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.2 0.8 GO:1903587 negative regulation of peptidyl-serine dephosphorylation(GO:1902309) regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.1 0.8 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.8 GO:0046469 platelet activating factor metabolic process(GO:0046469)
0.0 0.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.8 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.7 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 57 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.3 GO:0033268 node of Ranvier(GO:0033268)
0.2 1.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 1.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 0.9 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.9 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 0.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.7 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.7 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.6 GO:0043034 costamere(GO:0043034)
0.0 0.6 GO:0043679 axon terminus(GO:0043679)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.5 GO:0005827 polar microtubule(GO:0005827)
0.0 0.5 GO:0001739 sex chromatin(GO:0001739)
0.0 0.5 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.5 GO:0045202 synapse(GO:0045202)
0.1 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.4 GO:0035976 AP1 complex(GO:0035976)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 105 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 2.3 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.2 1.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.6 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 1.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 1.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 1.1 GO:0046965 retinoid X receptor binding(GO:0046965)
0.2 0.9 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.2 0.9 GO:0097001 ceramide binding(GO:0097001)
0.2 0.9 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 0.8 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.8 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.8 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.8 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 0.7 GO:0045545 syndecan binding(GO:0045545)
0.1 0.7 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.7 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.6 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.6 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 1.5 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.1 PID_TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 1.0 PID_HIV_NEF_PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.9 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 0.8 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 0.8 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.7 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.7 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.5 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.5 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 0.4 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.3 PID_IL1_PATHWAY IL1-mediated signaling events
0.0 0.3 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.2 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.2 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.2 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.0 0.2 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.1 PID_S1P_S1P2_PATHWAY S1P2 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.1 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.9 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.7 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.9 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.9 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 0.8 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.8 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.8 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.8 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.8 REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism
0.1 0.7 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.5 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.4 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.4 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.0 0.3 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.0 0.3 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling