Motif ID: Zfp282

Z-value: 0.638


Transcription factors associated with Zfp282:

Gene SymbolEntrez IDGene Name
Zfp282 ENSMUSG00000025821.9 Zfp282

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp282mm10_v2_chr6_+_47877204_47877204-0.262.9e-01Click!


Activity profile for motif Zfp282.

activity profile for motif Zfp282


Sorted Z-values histogram for motif Zfp282

Sorted Z-values for motif Zfp282



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp282

PNG image of the network

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Top targets:


Showing 1 to 20 of 80 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_-_35722330 1.524 ENSMUST00000133064.1
Ecscr
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr6_-_29507946 1.282 ENSMUST00000101614.3
ENSMUST00000078112.6
Kcp

kielin/chordin-like protein

chr9_+_34904913 1.160 ENSMUST00000045091.6
Kirrel3
kin of IRRE like 3 (Drosophila)
chr14_+_80000292 0.942 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr11_+_35121126 0.919 ENSMUST00000069837.3
Slit3
slit homolog 3 (Drosophila)
chr14_+_75955003 0.842 ENSMUST00000050120.2
Kctd4
potassium channel tetramerisation domain containing 4
chr7_-_28766469 0.699 ENSMUST00000085851.5
ENSMUST00000032815.4
Nfkbib

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta

chr9_+_18427543 0.631 ENSMUST00000053326.9
Gm5612
predicted gene 5612
chr14_-_70627008 0.621 ENSMUST00000110984.2
Dmtn
dematin actin binding protein
chr7_+_28766747 0.512 ENSMUST00000170068.1
ENSMUST00000072965.4
Sirt2

sirtuin 2

chr7_+_16738410 0.510 ENSMUST00000086112.6
Ap2s1
adaptor-related protein complex 2, sigma 1 subunit
chr16_-_85803106 0.496 ENSMUST00000023610.8
Adamts1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
chr7_-_25005895 0.438 ENSMUST00000102858.3
ENSMUST00000080882.6
Atp1a3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

chr12_+_70974621 0.424 ENSMUST00000160027.1
ENSMUST00000160864.1
Psma3

proteasome (prosome, macropain) subunit, alpha type 3

chr10_-_42018363 0.422 ENSMUST00000162405.1
ENSMUST00000095729.4
ENSMUST00000161081.1
ENSMUST00000160262.2
Armc2



armadillo repeat containing 2



chr14_+_31336633 0.345 ENSMUST00000022451.7
Capn7
calpain 7
chr3_-_88950401 0.344 ENSMUST00000090938.4
Dap3
death associated protein 3
chr5_+_137569851 0.341 ENSMUST00000031729.8
Tfr2
transferrin receptor 2
chr12_+_111538101 0.330 ENSMUST00000166123.1
Eif5
eukaryotic translation initiation factor 5
chr8_-_70776650 0.326 ENSMUST00000034296.8
Pik3r2
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.5 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 1.3 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.2 1.2 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.2 0.9 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0 0.9 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.7 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.2 0.6 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.2 0.5 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.1 0.5 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.4 GO:0036376 sodium ion export from cell(GO:0036376)
0.0 0.4 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.1 0.3 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) histone H2A K63-linked deubiquitination(GO:0070537)
0.1 0.3 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 0.3 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 0.3 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.2 GO:0070488 neutrophil aggregation(GO:0070488)
0.1 0.2 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.2 GO:0042097 interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.9 GO:0042581 specific granule(GO:0042581)
0.2 0.6 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.5 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.5 GO:0033010 paranodal junction(GO:0033010)
0.0 0.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.2 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)

Gene overrepresentation in molecular_function category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.9 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.6 GO:0030507 spectrin binding(GO:0030507)
0.1 0.5 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903)
0.1 0.4 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.4 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.3 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.3 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.2 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 0.2 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.2 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.0 0.2 GO:0050786 arachidonic acid binding(GO:0050544) RAGE receptor binding(GO:0050786)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:0048256 flap endonuclease activity(GO:0048256)

Gene overrepresentation in C2:CP category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.9 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.3 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 0.7 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.5 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.2 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.5 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.9 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.7 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.5 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.4 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.1 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs