Motif ID: Zfp384

Z-value: 1.135


Transcription factors associated with Zfp384:

Gene SymbolEntrez IDGene Name
Zfp384 ENSMUSG00000038346.12 Zfp384

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp384mm10_v2_chr6_+_125009665_125009805-0.175.1e-01Click!


Activity profile for motif Zfp384.

activity profile for motif Zfp384


Sorted Z-values histogram for motif Zfp384

Sorted Z-values for motif Zfp384



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp384

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103853199 5.375 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr7_-_100514800 2.147 ENSMUST00000054923.7
 Dnajb13
DnaJ (Hsp40) related, subfamily B, member 13
chr4_-_131838231 2.036 ENSMUST00000030741.2
ENSMUST00000105987.2
 Ptpru

protein tyrosine phosphatase, receptor type, U

chr2_+_165595009 1.998 ENSMUST00000088132.6
 Eya2
eyes absent 2 homolog (Drosophila)
chr6_-_23248264 1.949 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr5_-_135251209 1.938 ENSMUST00000062572.2
 Fzd9
frizzled homolog 9 (Drosophila)
chrX_+_103422010 1.912 ENSMUST00000182089.1
 Gm26992
predicted gene, 26992
chr9_-_91365778 1.890 ENSMUST00000065360.3
 Zic1
zinc finger protein of the cerebellum 1
chr9_-_91365756 1.781 ENSMUST00000034927.6
 Zic1
zinc finger protein of the cerebellum 1
chr13_+_94875600 1.727 ENSMUST00000022195.10
 Otp
orthopedia homolog (Drosophila)
chrX_-_106485214 1.713 ENSMUST00000039447.7
 Fndc3c1
fibronectin type III domain containing 3C1
chr16_-_26989974 1.693 ENSMUST00000089832.4
 Gmnc
geminin coiled-coil domain containing
chr11_+_54902917 1.682 ENSMUST00000149324.1
 Gpx3
glutathione peroxidase 3
chr17_+_87635974 1.624 ENSMUST00000053577.8
 Epcam
epithelial cell adhesion molecule
chr6_-_25690729 1.537 ENSMUST00000054867.6
 Gpr37
G protein-coupled receptor 37
chr17_-_70853482 1.511 ENSMUST00000118283.1
 Tgif1
TGFB-induced factor homeobox 1
chr11_+_54902743 1.477 ENSMUST00000082430.3
 Gpx3
glutathione peroxidase 3
chr13_-_53286052 1.471 ENSMUST00000021918.8
 Ror2
receptor tyrosine kinase-like orphan receptor 2
chr16_-_22161450 1.451 ENSMUST00000115379.1
 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr13_+_23544052 1.434 ENSMUST00000075558.2
 Hist1h3f
histone cluster 1, H3f

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 436 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 6.1 GO:0015671 oxygen transport(GO:0015671)
0.2 3.9 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 3.3 GO:0006334 nucleosome assembly(GO:0006334)
0.6 3.2 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.2 3.2 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.4 3.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 3.0 GO:0006270 DNA replication initiation(GO:0006270)
0.1 3.0 GO:0007628 adult walking behavior(GO:0007628)
0.0 2.9 GO:0006457 protein folding(GO:0006457)
0.7 2.2 GO:0097402 neuroblast migration(GO:0097402)
0.3 2.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 2.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 2.0 GO:0006342 chromatin silencing(GO:0006342)
0.6 1.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.6 1.9 GO:1990523 bone regeneration(GO:1990523)
0.2 1.9 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.5 1.8 GO:0019323 D-ribose metabolic process(GO:0006014) pentose catabolic process(GO:0019323)
0.2 1.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 1.8 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 1.7 GO:0001682 tRNA 5'-leader removal(GO:0001682)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 196 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.9 GO:0000786 nucleosome(GO:0000786)
0.7 5.5 GO:0005833 hemoglobin complex(GO:0005833)
0.0 3.9 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.3 3.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 3.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 2.6 GO:0031527 filopodium membrane(GO:0031527)
0.0 2.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.2 2.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 2.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.9 GO:0036126 sperm flagellum(GO:0036126)
0.0 1.9 GO:0005604 basement membrane(GO:0005604)
0.0 1.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 1.7 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.1 1.7 GO:0030057 desmosome(GO:0030057)
0.1 1.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 1.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.5 1.4 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.3 1.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 1.3 GO:0005876 spindle microtubule(GO:0005876)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 285 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.4 5.5 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.0 4.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 3.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.6 3.2 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.3 3.2 GO:0008430 selenium binding(GO:0008430)
0.1 3.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 3.2 GO:0051082 unfolded protein binding(GO:0051082)
0.0 2.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 2.7 GO:0070410 co-SMAD binding(GO:0070410)
0.0 2.7 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 2.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 2.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 2.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 2.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 2.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.7 2.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 1.9 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 1.9 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.0 1.9 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.6 1.8 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.2 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 4.0 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 3.9 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 3.4 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 3.1 PID_ALK1_PATHWAY ALK1 signaling events
0.1 2.6 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.1 2.3 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.2 PID_PLK1_PATHWAY PLK1 signaling events
0.2 2.0 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 2.0 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 1.8 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 1.6 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.6 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.6 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.5 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.4 PID_FGF_PATHWAY FGF signaling pathway
0.1 1.2 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.1 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.8 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.8 PID_E2F_PATHWAY E2F transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 95 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.4 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 4.4 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 3.8 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 2.6 REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND Genes involved in Processive synthesis on the lagging strand
0.1 2.5 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 2.5 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 2.2 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 2.1 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 2.1 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 2.0 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 1.9 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.8 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 1.8 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.2 1.7 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.6 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.6 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 1.5 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.5 REACTOME_KINESINS Genes involved in Kinesins
0.0 1.4 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.3 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing