Motif ID: Zfp524

Z-value: 0.812


Transcription factors associated with Zfp524:

Gene SymbolEntrez IDGene Name
Zfp524 ENSMUSG00000051184.6 Zfp524

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp524mm10_v2_chr7_+_5015466_50155090.136.0e-01Click!


Activity profile for motif Zfp524.

activity profile for motif Zfp524


Sorted Z-values histogram for motif Zfp524

Sorted Z-values for motif Zfp524



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp524

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_+_76660564 2.295 ENSMUST00000004294.10
 Kifc2
kinesin family member C2
chr11_-_6065737 2.045 ENSMUST00000002817.5
ENSMUST00000109813.2
ENSMUST00000090443.3
 Camk2b


calcium/calmodulin-dependent protein kinase II, beta


chr9_-_122862128 1.989 ENSMUST00000056467.7
 Zfp445
zinc finger protein 445
chr12_+_4917376 1.879 ENSMUST00000045664.5
 Atad2b
ATPase family, AAA domain containing 2B
chr15_-_79164477 1.775 ENSMUST00000040019.4
 Sox10
SRY-box containing gene 10
chr19_+_26623419 1.740 ENSMUST00000176584.1
 Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_-_69108039 1.635 ENSMUST00000121473.1
 Erbb4
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
chr5_+_76657673 1.616 ENSMUST00000128112.1
 C530008M17Rik
RIKEN cDNA C530008M17 gene
chr17_-_45686899 1.612 ENSMUST00000156254.1
 Tmem63b
transmembrane protein 63b
chr18_-_61911783 1.608 ENSMUST00000049378.8
ENSMUST00000166783.1
 Ablim3

actin binding LIM protein family, member 3

chr4_-_120747248 1.583 ENSMUST00000030376.7
 Kcnq4
potassium voltage-gated channel, subfamily Q, member 4
chr12_+_40446050 1.560 ENSMUST00000037488.6
 Dock4
dedicator of cytokinesis 4
chr2_-_24763047 1.529 ENSMUST00000100348.3
ENSMUST00000041342.5
ENSMUST00000114447.1
ENSMUST00000102939.2
ENSMUST00000070864.7
 Cacna1b




calcium channel, voltage-dependent, N type, alpha 1B subunit




chr17_-_6477102 1.487 ENSMUST00000167717.2
 Tmem181b-ps
transmembrane protein 181B, pseudogene
chr5_+_30711564 1.476 ENSMUST00000114729.1
 Dpysl5
dihydropyrimidinase-like 5
chr5_+_30711849 1.437 ENSMUST00000088081.4
ENSMUST00000101442.3
 Dpysl5

dihydropyrimidinase-like 5

chr5_+_110879788 1.393 ENSMUST00000156290.2
ENSMUST00000040111.9
 Ttc28

tetratricopeptide repeat domain 28

chr15_-_58076456 1.366 ENSMUST00000070143.6
ENSMUST00000110168.1
 Zhx1

zinc fingers and homeoboxes 1

chr7_+_3303643 1.360 ENSMUST00000172109.1
 Prkcg
protein kinase C, gamma
chr9_-_75611308 1.259 ENSMUST00000064433.3
 Tmod2
tropomodulin 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 195 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 2.9 GO:0015807 L-amino acid transport(GO:0015807)
0.1 2.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.7 2.1 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.4 2.0 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.2 2.0 GO:0033602 negative regulation of dopamine secretion(GO:0033602)
0.6 1.9 GO:0060003 elastin biosynthetic process(GO:0051542) copper ion export(GO:0060003)
0.0 1.9 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.2 1.8 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.2 1.8 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 1.8 GO:0033344 cholesterol efflux(GO:0033344)
0.0 1.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 1.7 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.4 1.6 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.4 1.6 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.3 1.6 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.1 1.6 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.1 1.6 GO:0061462 protein localization to lysosome(GO:0061462)
0.1 1.5 GO:0033574 response to testosterone(GO:0033574)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 89 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 12.7 GO:0014069 postsynaptic density(GO:0014069)
0.1 2.7 GO:0051233 spindle midzone(GO:0051233)
0.1 2.7 GO:0031901 early endosome membrane(GO:0031901)
0.1 2.5 GO:0071565 nBAF complex(GO:0071565)
0.2 1.9 GO:0097165 nuclear stress granule(GO:0097165)
0.1 1.9 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.2 1.8 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 1.8 GO:0005871 kinesin complex(GO:0005871)
0.0 1.7 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.7 GO:0001726 ruffle(GO:0001726)
0.2 1.6 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 1.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.3 1.5 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 1.5 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 1.2 GO:0031941 filamentous actin(GO:0031941)
0.0 1.2 GO:0032420 stereocilium(GO:0032420)
0.0 1.2 GO:0005776 autophagosome(GO:0005776)
0.1 1.1 GO:0097427 microtubule bundle(GO:0097427)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 133 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 3.2 GO:0008017 microtubule binding(GO:0008017)
0.1 3.0 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 3.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 2.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 2.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.6 1.9 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.1 1.9 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.5 1.8 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.3 1.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 1.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.8 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 1.8 GO:0003777 microtubule motor activity(GO:0003777)
0.3 1.5 GO:0038132 neuregulin binding(GO:0038132)
0.1 1.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.5 1.4 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 1.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.3 GO:0005523 tropomyosin binding(GO:0005523)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.5 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 2.1 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.9 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.7 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.7 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.1 1.6 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 1.6 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 1.4 PID_ATM_PATHWAY ATM pathway
0.0 1.4 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 1.1 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.9 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.8 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.6 PID_INSULIN_PATHWAY Insulin Pathway
0.0 0.6 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.5 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.0 0.5 PID_GMCSF_PATHWAY GMCSF-mediated signaling events
0.0 0.5 PID_VEGFR1_PATHWAY VEGFR1 specific signals
0.0 0.5 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 0.5 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.8 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 3.5 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 3.0 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 3.0 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.9 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.2 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 1.8 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.6 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.1 1.6 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 1.5 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.4 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 1.3 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 1.1 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 1.0 REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 1.0 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 1.0 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.9 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.8 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.1 0.7 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint