Motif ID: Zfp652

Z-value: 0.894


Transcription factors associated with Zfp652:

Gene SymbolEntrez IDGene Name
Zfp652 ENSMUSG00000075595.3 Zfp652

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp652mm10_v2_chr11_+_95712673_95712673-0.243.5e-01Click!


Activity profile for motif Zfp652.

activity profile for motif Zfp652


Sorted Z-values histogram for motif Zfp652

Sorted Z-values for motif Zfp652



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp652

PNG image of the network

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Top targets:


Showing 1 to 20 of 106 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_53707532 6.142 ENSMUST00000031093.3
Cckar
cholecystokinin A receptor
chr10_+_26229707 3.519 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr16_+_30065333 3.056 ENSMUST00000023171.7
Hes1
hairy and enhancer of split 1 (Drosophila)
chr10_-_92165159 3.003 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr1_-_138847579 2.648 ENSMUST00000093486.3
ENSMUST00000046870.6
Lhx9

LIM homeobox protein 9

chr12_+_55598917 2.322 ENSMUST00000051857.3
Insm2
insulinoma-associated 2
chr3_+_87971129 2.188 ENSMUST00000160694.1
Nes
nestin
chr3_+_87971071 2.180 ENSMUST00000090973.5
Nes
nestin
chr1_+_153665666 2.157 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chr7_-_25788635 2.108 ENSMUST00000002677.4
ENSMUST00000085948.4
Axl

AXL receptor tyrosine kinase

chrX_-_48034842 2.098 ENSMUST00000039026.7
Apln
apelin
chr2_+_167777467 2.029 ENSMUST00000139927.1
ENSMUST00000127441.1
Gm14321

predicted gene 14321

chr1_+_153665274 2.022 ENSMUST00000152114.1
ENSMUST00000111812.1
Rgs8

regulator of G-protein signaling 8

chr11_-_94242701 1.743 ENSMUST00000061469.3
Wfikkn2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr1_+_153665587 1.737 ENSMUST00000147700.1
Rgs8
regulator of G-protein signaling 8
chr1_+_153665627 1.732 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr4_-_63403330 1.717 ENSMUST00000035724.4
Akna
AT-hook transcription factor
chr14_+_73237891 1.707 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr3_-_116129615 1.649 ENSMUST00000029574.8
Vcam1
vascular cell adhesion molecule 1
chr1_+_184034381 1.542 ENSMUST00000048655.7
Dusp10
dual specificity phosphatase 10

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 7.6 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
2.0 6.1 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
1.0 3.1 GO:0021557 oculomotor nerve development(GO:0021557)
0.5 2.6 GO:0035262 gonad morphogenesis(GO:0035262)
0.7 2.1 GO:0097350 neutrophil clearance(GO:0097350)
0.7 2.1 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 1.7 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 1.7 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.1 1.6 GO:0061032 visceral serous pericardium development(GO:0061032)
0.3 1.5 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 1.4 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.3 1.3 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.2 1.3 GO:0015074 DNA integration(GO:0015074)
0.1 1.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 1.2 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 1.2 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.4 1.1 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.3 1.0 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.2 1.0 GO:0060032 notochord regression(GO:0060032)
0.1 1.0 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.1 GO:0043195 terminal bouton(GO:0043195)
0.1 6.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 4.3 GO:0005882 intermediate filament(GO:0005882)
0.1 2.1 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.0 1.7 GO:0001650 fibrillar center(GO:0001650)
0.0 1.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.2 GO:0031105 septin complex(GO:0031105)
0.1 1.0 GO:0097542 ciliary tip(GO:0097542)
0.1 0.9 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.9 GO:0005922 connexon complex(GO:0005922)
0.0 0.9 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.9 GO:0002102 podosome(GO:0002102)
0.0 0.9 GO:0016235 aggresome(GO:0016235)
0.0 0.9 GO:0016605 PML body(GO:0016605)
0.1 0.8 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.2 0.7 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.6 GO:0005921 gap junction(GO:0005921)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.4 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 7.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 6.1 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.2 4.6 GO:0008432 JUN kinase binding(GO:0008432)
0.5 4.4 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.2 2.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 2.1 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 1.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 1.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.4 1.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 1.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.5 GO:0070888 E-box binding(GO:0070888)
0.2 1.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 1.3 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 1.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 1.1 GO:0004849 uridine kinase activity(GO:0004849)
0.1 1.0 GO:0035014 retinoic acid binding(GO:0001972) phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 1.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.3 0.9 GO:0019966 interleukin-1 binding(GO:0019966)
0.3 0.9 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)

Gene overrepresentation in C2:CP category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.2 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.6 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.5 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.5 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.4 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 1.0 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.0 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.9 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 0.9 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.9 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.0 0.8 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.7 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 0.6 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.0 0.6 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.4 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.6 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.1 6.1 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 3.6 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.2 1.7 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 1.6 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.1 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.0 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 1.0 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 0.9 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.9 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.8 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.7 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.1 0.6 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.6 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.6 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.6 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.4 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport