Motif ID: Zfp691

Z-value: 0.505


Transcription factors associated with Zfp691:

Gene SymbolEntrez IDGene Name
Zfp691 ENSMUSG00000045268.7 Zfp691

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp691mm10_v2_chr4_-_119173849_119173901-0.532.3e-02Click!


Activity profile for motif Zfp691.

activity profile for motif Zfp691


Sorted Z-values histogram for motif Zfp691

Sorted Z-values for motif Zfp691



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp691

PNG image of the network

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Top targets:


Showing 1 to 20 of 101 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_128601106 0.958 ENSMUST00000117102.2
 Fzd10
frizzled homolog 10 (Drosophila)
chr9_+_62858085 0.953 ENSMUST00000034777.6
ENSMUST00000163820.1
 Calml4

calmodulin-like 4

chr7_+_28863831 0.841 ENSMUST00000138272.1
 Lgals7
lectin, galactose binding, soluble 7
chr17_-_23684019 0.815 ENSMUST00000085989.5
 Cldn9
claudin 9
chr13_+_53525703 0.797 ENSMUST00000081132.4
 Gm5449
predicted pseudogene 5449
chr8_+_88521344 0.700 ENSMUST00000034086.5
 Nkd1
naked cuticle 1 homolog (Drosophila)
chr10_-_77166545 0.628 ENSMUST00000081654.6
 Col18a1
collagen, type XVIII, alpha 1
chr9_-_108452377 0.620 ENSMUST00000035232.7
 Klhdc8b
kelch domain containing 8B
chr15_+_44196135 0.612 ENSMUST00000038856.6
ENSMUST00000110289.3
 Trhr

thyrotropin releasing hormone receptor

chr2_+_26591423 0.604 ENSMUST00000152988.2
ENSMUST00000149789.1
 Egfl7

EGF-like domain 7

chr8_+_72319033 0.597 ENSMUST00000067912.7
 Klf2
Kruppel-like factor 2 (lung)
chr1_-_138856819 0.581 ENSMUST00000112025.1
 2310009B15Rik
RIKEN cDNA 2310009B15 gene
chr9_-_58202281 0.553 ENSMUST00000163897.1
 Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr7_+_143069249 0.542 ENSMUST00000060433.3
ENSMUST00000133410.2
ENSMUST00000105920.1
ENSMUST00000177841.1
ENSMUST00000147995.1
ENSMUST00000137856.1
 Tssc4





tumor-suppressing subchromosomal transferable fragment 4





chr9_-_21067093 0.517 ENSMUST00000115494.2
 Zglp1
zinc finger, GATA-like protein 1
chr7_-_45061706 0.500 ENSMUST00000107832.1
 Prrg2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr13_-_55528511 0.490 ENSMUST00000047877.4
 Dok3
docking protein 3
chr9_+_50603892 0.456 ENSMUST00000044051.4
 Timm8b
translocase of inner mitochondrial membrane 8B
chr3_-_92429403 0.452 ENSMUST00000047300.7
 Gm9774
predicted pseudogene 9774
chr7_-_45061651 0.451 ENSMUST00000007981.3
ENSMUST00000107831.1
 Prrg2

proline-rich Gla (G-carboxyglutamic acid) polypeptide 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.7 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 0.8 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.6 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.1 0.6 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.6 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.6 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.2 0.5 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.0 0.5 GO:0048599 oocyte development(GO:0048599)
0.1 0.4 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.1 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.4 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 0.3 GO:0051105 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.1 0.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.3 GO:0097503 sialylation(GO:0097503)
0.0 0.3 GO:0033572 transferrin transport(GO:0033572)
0.1 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.2 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.1 0.2 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829)
0.1 0.2 GO:1904154 trimming of terminal mannose on B branch(GO:0036509) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 0.8 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.4 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 0.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.4 GO:0043203 axon hillock(GO:0043203)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.3 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.3 GO:0097255 R2TP complex(GO:0097255)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.3 GO:0000800 lateral element(GO:0000800)
0.0 0.3 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.2 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 0.8 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.8 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.1 0.5 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.5 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.3 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.3 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.3 GO:0008373 sialyltransferase activity(GO:0008373)
0.1 0.2 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.2 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.7 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.6 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.9 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.9 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.3 REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.2 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle