Motif ID: Zfx_Zfp711

Z-value: 2.879

Transcription factors associated with Zfx_Zfp711:

Gene SymbolEntrez IDGene Name
Zfp711 ENSMUSG00000025529.8 Zfp711
Zfx ENSMUSG00000079509.4 Zfx

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp711mm10_v2_chrX_+_112604274_112604274-0.735.9e-04Click!
Zfxmm10_v2_chrX_-_94123359_94123412-0.419.5e-02Click!


Activity profile for motif Zfx_Zfp711.

activity profile for motif Zfx_Zfp711


Sorted Z-values histogram for motif Zfx_Zfp711

Sorted Z-values for motif Zfx_Zfp711



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfx_Zfp711

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_37776229 6.786 ENSMUST00000050372.7
 Crb2
crumbs homolog 2 (Drosophila)
chr7_+_144896523 4.901 ENSMUST00000033389.5
 Fgf15
fibroblast growth factor 15
chr4_+_109978004 4.358 ENSMUST00000061187.3
 Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr11_-_12037391 4.072 ENSMUST00000093321.5
 Grb10
growth factor receptor bound protein 10
chr18_+_9212856 3.816 ENSMUST00000041080.5
 Fzd8
frizzled homolog 8 (Drosophila)
chr15_-_98004695 3.696 ENSMUST00000023123.8
 Col2a1
collagen, type II, alpha 1
chr9_-_119578981 3.571 ENSMUST00000117911.1
ENSMUST00000120420.1
 Scn5a

sodium channel, voltage-gated, type V, alpha

chr3_-_8667033 3.501 ENSMUST00000042412.3
 Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr8_+_127064107 3.413 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
 Pard3








par-3 (partitioning defective 3) homolog (C. elegans)








chr14_+_59625281 3.412 ENSMUST00000053949.5
 Shisa2
shisa homolog 2 (Xenopus laevis)
chr12_+_108334341 3.409 ENSMUST00000021684.4
 Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr7_-_38107490 3.329 ENSMUST00000108023.3
 Ccne1
cyclin E1
chr10_-_77113676 3.237 ENSMUST00000072755.4
ENSMUST00000105409.1
 Col18a1

collagen, type XVIII, alpha 1

chr4_+_137468767 3.225 ENSMUST00000030547.8
ENSMUST00000171332.1
 Hspg2

perlecan (heparan sulfate proteoglycan 2)

chr11_+_94327984 3.206 ENSMUST00000107818.2
ENSMUST00000051221.6
 Ankrd40

ankyrin repeat domain 40

chr15_-_98004634 3.150 ENSMUST00000131560.1
ENSMUST00000088355.5
 Col2a1

collagen, type II, alpha 1

chr19_-_30175414 3.148 ENSMUST00000025778.7
 Gldc
glycine decarboxylase
chr2_+_172549581 3.104 ENSMUST00000030391.2
 Tfap2c
transcription factor AP-2, gamma
chr19_+_25610533 3.084 ENSMUST00000048935.4
 Dmrt3
doublesex and mab-3 related transcription factor 3
chr7_-_137314394 3.054 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
 Ebf3



early B cell factor 3




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 1,169 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 12.8 GO:0045454 cell redox homeostasis(GO:0045454)
1.0 11.0 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.3 9.9 GO:0035329 hippo signaling(GO:0035329)
0.4 8.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.7 7.5 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 7.2 GO:0006270 DNA replication initiation(GO:0006270)
0.9 7.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
2.3 7.0 GO:0014028 notochord formation(GO:0014028)
0.2 7.0 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
1.1 6.5 GO:0042660 positive regulation of cell fate specification(GO:0042660)
0.7 6.5 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.4 6.4 GO:0030220 platelet formation(GO:0030220)
0.4 6.1 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
1.2 5.9 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.5 5.8 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
1.9 5.7 GO:0060853 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel endothelial cell fate specification(GO:0097101)
1.1 5.6 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.4 5.6 GO:0006999 nuclear pore organization(GO:0006999)
0.4 5.6 GO:0006337 nucleosome disassembly(GO:0006337)
0.7 5.5 GO:0048852 diencephalon morphogenesis(GO:0048852)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 389 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 41.3 GO:0070062 extracellular exosome(GO:0070062)
0.3 24.0 GO:0005643 nuclear pore(GO:0005643)
0.1 17.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.2 15.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 13.9 GO:0005667 transcription factor complex(GO:0005667)
0.1 12.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.2 11.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 8.6 GO:0005811 lipid particle(GO:0005811)
0.9 7.8 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 7.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 7.6 GO:0005925 focal adhesion(GO:0005925)
0.2 7.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.3 6.9 GO:0001741 XY body(GO:0001741)
0.8 6.6 GO:0033269 internode region of axon(GO:0033269)
0.4 6.3 GO:0070938 contractile ring(GO:0070938)
0.2 5.9 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.3 5.8 GO:0071564 npBAF complex(GO:0071564)
0.1 5.6 GO:0005581 collagen trimer(GO:0005581)
0.0 5.6 GO:0016604 nuclear body(GO:0016604)
0.3 5.5 GO:0016580 Sin3 complex(GO:0016580)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 631 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 26.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.7 21.0 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 15.5 GO:0045296 cadherin binding(GO:0045296)
0.5 14.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 13.3 GO:0035326 enhancer binding(GO:0035326)
0.7 11.5 GO:0003680 AT DNA binding(GO:0003680)
0.1 10.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 10.0 GO:0001047 core promoter binding(GO:0001047)
0.3 9.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
1.8 8.9 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.2 8.6 GO:0017025 TBP-class protein binding(GO:0017025)
0.2 8.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 8.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.1 8.3 GO:0005080 protein kinase C binding(GO:0005080)
0.1 8.3 GO:0008026 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.9 7.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.4 7.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
1.4 6.9 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 6.9 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
1.2 6.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 107 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 21.9 PID_INTEGRIN1_PATHWAY Beta1 integrin cell surface interactions
0.7 21.8 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.3 18.9 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.3 17.3 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.2 16.0 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.5 15.6 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 13.8 PID_E2F_PATHWAY E2F transcription factor network
0.3 10.7 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.2 10.6 PID_BMP_PATHWAY BMP receptor signaling
0.1 10.3 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 9.6 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.3 9.4 PID_BARD1_PATHWAY BARD1 signaling events
0.3 8.4 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.2 8.3 PID_ATR_PATHWAY ATR signaling pathway
0.6 8.1 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 8.0 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.2 6.7 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.2 6.6 PID_IGF1_PATHWAY IGF1 pathway
0.2 6.4 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.2 6.4 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 181 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 24.2 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.2 14.5 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.7 13.7 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.5 13.1 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 12.8 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.2 12.2 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 12.0 REACTOME_TRANSLATION Genes involved in Translation
0.4 11.7 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.2 10.9 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.4 10.7 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.3 10.4 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.6 9.9 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 9.1 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.3 8.5 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 7.8 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.3 7.0 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.1 6.9 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 6.6 REACTOME_UNFOLDED_PROTEIN_RESPONSE Genes involved in Unfolded Protein Response
0.3 6.4 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.3 6.2 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism