Motif ID: Zkscan1

Z-value: 0.647


Transcription factors associated with Zkscan1:

Gene SymbolEntrez IDGene Name
Zkscan1 ENSMUSG00000029729.6 Zkscan1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zkscan1mm10_v2_chr5_+_138085083_138085147-0.194.4e-01Click!


Activity profile for motif Zkscan1.

activity profile for motif Zkscan1


Sorted Z-values histogram for motif Zkscan1

Sorted Z-values for motif Zkscan1



Network of associatons between targets according to the STRING database.



First level regulatory network of Zkscan1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 118 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_61228396 2.129 ENSMUST00000076046.6
 Csf2ra
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr15_-_79164477 1.509 ENSMUST00000040019.4
 Sox10
SRY-box containing gene 10
chr19_-_45742873 1.136 ENSMUST00000026241.5
ENSMUST00000026240.7
ENSMUST00000111928.1
 Fgf8


fibroblast growth factor 8


chr5_-_28210022 0.984 ENSMUST00000118882.1
 Cnpy1
canopy 1 homolog (zebrafish)
chr4_+_129960760 0.847 ENSMUST00000139884.1
 1700003M07Rik
RIKEN cDNA 1700003M07 gene
chr2_+_84734050 0.704 ENSMUST00000090729.2
 Ypel4
yippee-like 4 (Drosophila)
chr7_+_112225856 0.702 ENSMUST00000050149.5
ENSMUST00000106647.1
ENSMUST00000106648.1
 Mical2


microtubule associated monooxygenase, calponin and LIM domain containing 2


chr12_+_73997749 0.644 ENSMUST00000110451.2
 Syt16
synaptotagmin XVI
chr15_-_78572754 0.616 ENSMUST00000043214.6
 Rac2
RAS-related C3 botulinum substrate 2
chr6_+_83711232 0.578 ENSMUST00000037807.1
 Vax2
ventral anterior homeobox containing gene 2
chr17_+_34039437 0.575 ENSMUST00000131134.1
ENSMUST00000087497.4
ENSMUST00000114255.1
ENSMUST00000114252.1
 Col11a2



collagen, type XI, alpha 2



chr17_+_33524170 0.567 ENSMUST00000087623.6
 Adamts10
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10
chr14_-_30353468 0.542 ENSMUST00000112249.1
 Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr12_+_109545390 0.539 ENSMUST00000146701.1
 Meg3
maternally expressed 3
chr4_+_74013442 0.526 ENSMUST00000098006.2
ENSMUST00000084474.5
 Frmd3

FERM domain containing 3

chr7_+_24370255 0.520 ENSMUST00000171904.1
 Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chrX_+_20870166 0.491 ENSMUST00000115342.3
ENSMUST00000009530.4
 Timp1

tissue inhibitor of metalloproteinase 1

chr1_+_171840607 0.490 ENSMUST00000136479.1
ENSMUST00000042302.6
 Cd84

CD84 antigen

chr1_-_56969864 0.482 ENSMUST00000177424.1
 Satb2
special AT-rich sequence binding protein 2
chr14_+_34673888 0.475 ENSMUST00000048263.7
 Wapal
wings apart-like homolog (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.1 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.3 1.5 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.1 1.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.4 1.1 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.8 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.7 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.2 0.6 GO:0060023 soft palate development(GO:0060023)
0.1 0.6 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.0 0.6 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.6 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.2 0.5 GO:2001180 negative regulation of interleukin-18 production(GO:0032701) negative regulation of interleukin-10 secretion(GO:2001180)
0.1 0.5 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.5 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.5 GO:0046541 stabilization of membrane potential(GO:0030322) saliva secretion(GO:0046541) positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.5 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.4 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.4 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.4 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1 0.3 GO:0035880 embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.1 0.3 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.5 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.1 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.4 1.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0071949 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) FAD binding(GO:0071949)
0.1 0.6 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.5 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.4 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.4 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.4 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.3 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)

Gene overrepresentation in C2:CP category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.9 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.1 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.6 PID_IL8_CXCR2_PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.6 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.5 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.4 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.1 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.1 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.6 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.5 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 0.4 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors