Motif ID: Zkscan3

Z-value: 0.295


Transcription factors associated with Zkscan3:

Gene SymbolEntrez IDGene Name
Zkscan3 ENSMUSG00000021327.12 Zkscan3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zkscan3mm10_v2_chr13_-_21402688_21402755-0.617.3e-03Click!


Activity profile for motif Zkscan3.

activity profile for motif Zkscan3


Sorted Z-values histogram for motif Zkscan3

Sorted Z-values for motif Zkscan3



Network of associatons between targets according to the STRING database.



First level regulatory network of Zkscan3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_75422524 0.378 ENSMUST00000125982.1
ENSMUST00000137103.1
 Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr11_-_75422586 0.349 ENSMUST00000138661.1
ENSMUST00000000769.7
 Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr5_+_24985840 0.312 ENSMUST00000075081.6
 1500035N22Rik
RIKEN cDNA 1500035N22 gene
chr8_-_70760889 0.297 ENSMUST00000038626.8
 Mpv17l2
MPV17 mitochondrial membrane protein-like 2
chr1_+_132298606 0.279 ENSMUST00000046071.4
 Klhdc8a
kelch domain containing 8A
chr7_-_81345189 0.242 ENSMUST00000080813.4
 Rps17
ribosomal protein S17
chr2_+_32646586 0.234 ENSMUST00000009705.7
ENSMUST00000167841.1
 Eng

endoglin

chr1_+_37997975 0.219 ENSMUST00000027252.7
 Eif5b
eukaryotic translation initiation factor 5B
chr7_+_101896340 0.212 ENSMUST00000035395.7
ENSMUST00000106973.1
ENSMUST00000144207.1
 Anapc15


anaphase prompoting complex C subunit 15


chr2_+_104069819 0.211 ENSMUST00000111131.2
ENSMUST00000111132.1
ENSMUST00000129749.1
 Cd59b


CD59b antigen


chr13_-_19395728 0.192 ENSMUST00000039694.7
 Stard3nl
STARD3 N-terminal like
chr7_+_126759601 0.189 ENSMUST00000050201.4
ENSMUST00000057669.9
 Mapk3

mitogen-activated protein kinase 3

chr17_+_46110982 0.172 ENSMUST00000024763.3
ENSMUST00000123646.1
 Mrps18a

mitochondrial ribosomal protein S18A

chr8_+_33732237 0.167 ENSMUST00000171010.1
 Gtf2e2
general transcription factor II E, polypeptide 2 (beta subunit)
chr3_+_146500071 0.167 ENSMUST00000119130.1
 Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr8_+_71396853 0.163 ENSMUST00000002473.8
 Babam1
BRISC and BRCA1 A complex member 1
chr18_+_61105844 0.163 ENSMUST00000115268.3
 Csf1r
colony stimulating factor 1 receptor
chr17_-_35673738 0.163 ENSMUST00000001565.8
 Gtf2h4
general transcription factor II H, polypeptide 4
chr8_+_31091593 0.149 ENSMUST00000161713.1
 Dusp26
dual specificity phosphatase 26 (putative)
chr4_+_63544747 0.143 ENSMUST00000035301.6
 Atp6v1g1
ATPase, H+ transporting, lysosomal V1 subunit G1
chr12_+_69724939 0.140 ENSMUST00000021372.5
 Atp5s
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s
chr17_-_35673517 0.133 ENSMUST00000162266.1
ENSMUST00000160734.1
ENSMUST00000159852.1
ENSMUST00000160039.1
 Gtf2h4



general transcription factor II H, polypeptide 4



chr8_+_94810446 0.128 ENSMUST00000034232.1
 Ccl17
chemokine (C-C motif) ligand 17
chr3_+_146499850 0.127 ENSMUST00000118280.1
 Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr1_+_135232045 0.124 ENSMUST00000110798.3
 Gm4204
predicted gene 4204
chr7_-_127020321 0.122 ENSMUST00000032918.2
 Pagr1a
PAXIP1 associated glutamate rich protein 1A
chr11_-_102365111 0.112 ENSMUST00000006749.9
 Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr2_+_156613664 0.109 ENSMUST00000169464.2
ENSMUST00000109567.3
 Dlgap4

discs, large homolog-associated protein 4 (Drosophila)

chr4_+_139192899 0.102 ENSMUST00000102508.3
ENSMUST00000131912.1
ENSMUST00000102507.3
 Capzb


capping protein (actin filament) muscle Z-line, beta


chr13_-_38658991 0.102 ENSMUST00000001757.7
 Eef1e1
eukaryotic translation elongation factor 1 epsilon 1
chr10_+_80629646 0.100 ENSMUST00000085435.5
 Csnk1g2
casein kinase 1, gamma 2
chr12_+_112588753 0.095 ENSMUST00000101029.2
 Inf2
inverted formin, FH2 and WH2 domain containing
chr8_-_13200576 0.094 ENSMUST00000165605.2
 Grtp1
GH regulated TBC protein 1
chr2_+_104095796 0.092 ENSMUST00000040423.5
ENSMUST00000168176.1
 Cd59a

CD59a antigen

chr9_+_108648720 0.092 ENSMUST00000098384.2
 Gm10621
predicted gene 10621
chr6_+_125552948 0.088 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
 Vwf


Von Willebrand factor homolog


chr8_-_105758570 0.087 ENSMUST00000155038.2
ENSMUST00000013294.9
 Gfod2

glucose-fructose oxidoreductase domain containing 2

chr5_-_73338580 0.084 ENSMUST00000087195.5
 Ociad2
OCIA domain containing 2
chr5_-_88675613 0.080 ENSMUST00000113234.1
ENSMUST00000153565.1
 Grsf1

G-rich RNA sequence binding factor 1

chr1_-_173333503 0.078 ENSMUST00000038227.4
 Darc
Duffy blood group, chemokine receptor
chr13_-_32851176 0.074 ENSMUST00000091668.5
ENSMUST00000076352.6
 Serpinb1a

serine (or cysteine) peptidase inhibitor, clade B, member 1a

chr19_-_10869757 0.073 ENSMUST00000120524.1
ENSMUST00000025645.7
 Tmem132a

transmembrane protein 132A

chr2_+_31670714 0.071 ENSMUST00000038474.7
ENSMUST00000137156.1
 Exosc2

exosome component 2

chr4_+_15957923 0.069 ENSMUST00000029879.8
ENSMUST00000149069.1
 Nbn

nibrin

chr8_+_106893616 0.067 ENSMUST00000047629.5
 Cirh1a
cirrhosis, autosomal recessive 1A (human)
chr8_+_70616816 0.064 ENSMUST00000052437.3
 Lrrc25
leucine rich repeat containing 25
chr8_-_106893581 0.062 ENSMUST00000176437.1
ENSMUST00000177068.1
ENSMUST00000169312.1
ENSMUST00000176515.1
 Chtf8



CTF8, chromosome transmission fidelity factor 8



chr10_-_33951190 0.059 ENSMUST00000048222.4
 Zufsp
zinc finger with UFM1-specific peptidase domain
chr19_+_6276725 0.056 ENSMUST00000025684.3
 Ehd1
EH-domain containing 1
chr15_-_3979432 0.053 ENSMUST00000022791.8
 Fbxo4
F-box protein 4
chr5_+_24586721 0.050 ENSMUST00000121863.1
ENSMUST00000088295.4
 Chpf2

chondroitin polymerizing factor 2

chr6_-_122856151 0.043 ENSMUST00000042081.8
 C3ar1
complement component 3a receptor 1
chr6_-_113719880 0.038 ENSMUST00000064993.5
 Ghrl
ghrelin
chr9_+_114688782 0.036 ENSMUST00000047404.6
 Dync1li1
dynein cytoplasmic 1 light intermediate chain 1
chrX_-_17571563 0.029 ENSMUST00000177213.1
 Fundc1
FUN14 domain containing 1
chr12_+_32954179 0.029 ENSMUST00000020885.6
 Sypl
synaptophysin-like protein
chrX_-_17572241 0.028 ENSMUST00000176638.1
ENSMUST00000026016.6
 Fundc1

FUN14 domain containing 1

chr2_-_30194112 0.020 ENSMUST00000113659.1
ENSMUST00000113660.1
 Ccbl1

cysteine conjugate-beta lyase 1

chr18_+_82554463 0.020 ENSMUST00000062446.7
ENSMUST00000102812.4
ENSMUST00000075372.5
ENSMUST00000080658.4
ENSMUST00000152071.1
ENSMUST00000114674.3
ENSMUST00000142850.1
ENSMUST00000133193.1
ENSMUST00000123251.1
ENSMUST00000153478.1
ENSMUST00000132369.1
 Mbp










myelin basic protein










chr16_-_16359016 0.017 ENSMUST00000023477.7
ENSMUST00000096229.3
ENSMUST00000115749.1
 Dnm1l


dynamin 1-like


chr1_+_58795371 0.011 ENSMUST00000027189.8
 Casp8
caspase 8
chr8_-_116978908 0.011 ENSMUST00000070577.5
 1700030J22Rik
RIKEN cDNA 1700030J22 gene
chr13_-_100786402 0.010 ENSMUST00000174038.1
ENSMUST00000091295.7
ENSMUST00000072119.8
 Ccnb1


cyclin B1


chr7_-_27228605 0.008 ENSMUST00000003850.7
 Itpkc
inositol 1,4,5-trisphosphate 3-kinase C
chr1_-_40790642 0.006 ENSMUST00000039672.5
 Mfsd9
major facilitator superfamily domain containing 9
chr11_-_100650693 0.004 ENSMUST00000103119.3
 Zfp385c
zinc finger protein 385C
chr2_-_66634952 0.003 ENSMUST00000100064.2
ENSMUST00000100063.2
 Scn9a

sodium channel, voltage-gated, type IX, alpha


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 0.2 GO:1905072 detection of oxygen(GO:0003032) cardiac jelly development(GO:1905072)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.3 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.2 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.0 0.2 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.2 GO:0000189 MAPK import into nucleus(GO:0000189)
0.0 0.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.3 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.1 GO:0090272 negative regulation of fibroblast growth factor production(GO:0090272)
0.0 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304) histone H3-K27 demethylation(GO:0071557)
0.0 0.0 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.0 GO:0035482 intestine smooth muscle contraction(GO:0014827) gastric motility(GO:0035482) gastric emptying(GO:0035483) regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938) positive regulation of cortisol secretion(GO:0051464) positive regulation of adipose tissue development(GO:1904179) regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) regulation of small intestine smooth muscle contraction(GO:1904347) small intestine smooth muscle contraction(GO:1990770)
0.0 0.1 GO:0006968 cellular defense response(GO:0006968)
0.0 0.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.3 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1 0.2 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 0.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.7 GO:0043203 axon hillock(GO:0043203)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0044666 MLL3/4 complex(GO:0044666)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.2 GO:0005534 galactose binding(GO:0005534)
0.0 0.3 GO:0001848 complement binding(GO:0001848)
0.0 0.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0004707 MAP kinase activity(GO:0004707)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID_S1P_S1P4_PATHWAY S1P4 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.2 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade