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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
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Results for AACCUGG
Z-value: 1.08
Motif logo
miRNA associated with seed AACCUGG
| Name | miRBASE accession |
|---|---|
|
hsa-miR-490-3p
|
MIMAT0002806 |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chrX_+_123095155 Show fit | 2.38 |
ENST00000371160.1
ENST00000435103.1 |
stromal antigen 2 |
|
| chr19_+_34919257 Show fit | 1.35 |
ENST00000246548.4
ENST00000590048.2 |
ubiquitin-like modifier activating enzyme 2 |
|
| chr1_+_93811438 Show fit | 1.32 |
ENST00000370272.4
ENST00000370267.1 |
down-regulator of transcription 1, TBP-binding (negative cofactor 2) |
|
| chr8_-_103876965 Show fit | 1.23 |
ENST00000337198.5
|
antizyme inhibitor 1 |
|
| chr7_-_26240357 Show fit | 1.06 |
ENST00000354667.4
ENST00000356674.7 |
heterogeneous nuclear ribonucleoprotein A2/B1 |
|
| chr1_+_193091080 Show fit | 0.96 |
ENST00000367435.3
|
cell division cycle 73 |
|
| chr11_+_125462690 Show fit | 0.96 |
ENST00000392708.4
ENST00000529196.1 ENST00000531491.1 |
STT3A, subunit of the oligosaccharyltransferase complex (catalytic) |
|
| chr14_+_57735614 Show fit | 0.90 |
ENST00000261558.3
|
adaptor-related protein complex 5, mu 1 subunit |
|
| chr12_-_123011536 Show fit | 0.87 |
ENST00000331738.7
ENST00000354654.2 |
arginine/serine-rich coiled-coil 2 |
|
| chr8_-_17104356 Show fit | 0.81 |
ENST00000361272.4
ENST00000523917.1 |
CCR4-NOT transcription complex, subunit 7 |
Network of associatons between targets according to the STRING database.
First level regulatory network of AACCUGG
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.4 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.0 | 1.3 | GO:0043966 | histone H3 acetylation(GO:0043966) |
| 0.3 | 1.2 | GO:0033387 | putrescine biosynthetic process from ornithine(GO:0033387) |
| 0.2 | 1.1 | GO:0044806 | G-quadruplex DNA unwinding(GO:0044806) |
| 0.1 | 1.0 | GO:0001711 | endodermal cell fate commitment(GO:0001711) |
| 0.0 | 1.0 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
| 0.1 | 0.8 | GO:0060339 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) negative regulation of type I interferon-mediated signaling pathway(GO:0060339) |
| 0.1 | 0.7 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.1 | 0.7 | GO:2000587 | negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587) |
| 0.2 | 0.6 | GO:0090283 | regulation of protein glycosylation in Golgi(GO:0090283) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.0 | GO:0000775 | chromosome, centromeric region(GO:0000775) |
| 0.3 | 1.4 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
| 0.1 | 1.3 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.0 | 1.1 | GO:0015030 | Cajal body(GO:0015030) |
| 0.1 | 1.0 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.1 | 1.0 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.0 | 0.9 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
| 0.2 | 0.8 | GO:0044094 | host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094) |
| 0.0 | 0.7 | GO:0002102 | podosome(GO:0002102) |
| 0.1 | 0.6 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.7 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.2 | 1.4 | GO:0044388 | small protein activating enzyme binding(GO:0044388) |
| 0.2 | 1.2 | GO:0042978 | ornithine decarboxylase activator activity(GO:0042978) |
| 0.1 | 1.1 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 0.1 | 1.0 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.0 | 1.0 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.0 | 0.8 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.0 | 0.7 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.0 | 0.6 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.1 | 0.5 | GO:1990189 | peptide-serine-N-acetyltransferase activity(GO:1990189) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.4 | PID PLK1 PATHWAY | PLK1 signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.9 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 1.6 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 1.3 | REACTOME ASPARAGINE N LINKED GLYCOSYLATION | Genes involved in Asparagine N-linked glycosylation |
| 0.0 | 1.2 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.0 | 0.8 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 0.7 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 0.6 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |