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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for AGCCCUU

Z-value: 1.27

Motif logo

logo of

miRNA associated with seed AGCCCUU

NamemiRBASE accession
hsa-miR-129-1-3p
MIMAT0004548
hsa-miR-129-2-3p
MIMAT0004605

Activity profile of AGCCCUU motif

Sorted Z-values of AGCCCUU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_13956737 28.75 ENST00000454189.2
GPM6B
glycoprotein M6B
chr1_-_20812690 24.15 ENST00000375078.3
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr6_-_46293378 23.02 ENST00000330430.6
RCAN2
regulator of calcineurin 2
chr11_-_123525289 16.95 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
SCN3B
sodium channel, voltage-gated, type III, beta subunit
chr2_+_203499901 15.25 ENST00000303116.6
ENST00000392238.2
FAM117B
family with sequence similarity 117, member B
chr17_+_43971643 14.14 ENST00000344290.5
ENST00000262410.5
ENST00000351559.5
ENST00000340799.5
ENST00000535772.1
ENST00000347967.5
MAPT
microtubule-associated protein tau
chr5_-_136834982 13.24 ENST00000510689.1
ENST00000394945.1
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr1_-_41131326 12.77 ENST00000372684.3
RIMS3
regulating synaptic membrane exocytosis 3
chr22_+_40390930 12.69 ENST00000333407.6
FAM83F
family with sequence similarity 83, member F
chr8_+_104152922 12.06 ENST00000309982.5
ENST00000438105.2
ENST00000297574.6
BAALC
brain and acute leukemia, cytoplasmic
chr11_+_121322832 11.41 ENST00000260197.7
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr14_-_45431091 10.89 ENST00000579157.1
ENST00000396128.4
ENST00000556500.1
KLHL28
kelch-like family member 28
chr15_-_48470558 10.88 ENST00000324324.7
MYEF2
myelin expression factor 2
chr15_-_83316254 10.39 ENST00000567678.1
ENST00000450751.2
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr9_-_101471479 9.87 ENST00000259455.2
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr20_-_48532019 9.61 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr10_+_74451883 9.56 ENST00000373053.3
ENST00000357157.6
MCU
mitochondrial calcium uniporter
chr6_-_136871957 9.33 ENST00000354570.3
MAP7
microtubule-associated protein 7
chr11_+_123396528 9.02 ENST00000322282.7
ENST00000529750.1
GRAMD1B
GRAM domain containing 1B
chrX_+_110339439 8.88 ENST00000372010.1
ENST00000519681.1
ENST00000372007.5
PAK3
p21 protein (Cdc42/Rac)-activated kinase 3
chr11_-_22851367 8.50 ENST00000354193.4
SVIP
small VCP/p97-interacting protein
chr5_+_161274685 8.25 ENST00000428797.2
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr5_+_65018017 7.85 ENST00000380985.5
ENST00000502464.1
NLN
neurolysin (metallopeptidase M3 family)
chr1_+_205012293 7.17 ENST00000331830.4
CNTN2
contactin 2 (axonal)
chr19_+_54466179 6.95 ENST00000270458.2
CACNG8
calcium channel, voltage-dependent, gamma subunit 8
chr4_-_90229142 6.45 ENST00000609438.1
GPRIN3
GPRIN family member 3
chr21_-_32931290 6.41 ENST00000286827.3
TIAM1
T-cell lymphoma invasion and metastasis 1
chr12_-_49110613 6.34 ENST00000261900.3
CCNT1
cyclin T1
chr12_-_6798523 6.33 ENST00000319770.3
ZNF384
zinc finger protein 384
chr4_-_36246060 6.11 ENST00000303965.4
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr7_-_71801980 5.88 ENST00000329008.5
CALN1
calneuron 1
chr8_-_82024290 5.83 ENST00000220597.4
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr6_-_99873145 5.78 ENST00000369239.5
ENST00000438806.1
PNISR
PNN-interacting serine/arginine-rich protein
chr20_-_48099182 5.68 ENST00000371741.4
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr14_+_85996471 5.38 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr6_+_44238203 5.27 ENST00000451188.2
TMEM151B
transmembrane protein 151B
chr9_-_21335356 5.12 ENST00000359039.4
KLHL9
kelch-like family member 9
chr15_-_73925651 5.08 ENST00000545878.1
ENST00000287226.8
ENST00000345330.4
NPTN
neuroplastin
chr15_+_44580899 4.81 ENST00000559222.1
ENST00000299957.6
CASC4
cancer susceptibility candidate 4
chr4_-_76439596 4.50 ENST00000451788.1
ENST00000512706.1
RCHY1
ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chr16_-_4292071 4.49 ENST00000399609.3
SRL
sarcalumenin
chr3_+_32147997 4.38 ENST00000282541.5
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr5_+_139493665 4.34 ENST00000331327.3
PURA
purine-rich element binding protein A
chr2_+_70142189 4.12 ENST00000264444.2
MXD1
MAX dimerization protein 1
chr11_-_117186946 4.09 ENST00000313005.6
ENST00000528053.1
BACE1
beta-site APP-cleaving enzyme 1
chr19_-_11591848 3.98 ENST00000359227.3
ELAVL3
ELAV like neuron-specific RNA binding protein 3
chr10_-_118764862 3.91 ENST00000260777.10
KIAA1598
KIAA1598
chr4_-_39640700 3.91 ENST00000295958.5
SMIM14
small integral membrane protein 14
chr9_+_131843377 3.82 ENST00000372546.4
ENST00000406974.3
ENST00000540102.1
DOLPP1
dolichyldiphosphatase 1
chr15_-_78423886 3.82 ENST00000258930.3
CIB2
calcium and integrin binding family member 2
chr3_-_114790179 3.80 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr1_+_110527308 3.74 ENST00000369799.5
AHCYL1
adenosylhomocysteinase-like 1
chr16_+_19535133 3.56 ENST00000396212.2
ENST00000381396.5
CCP110
centriolar coiled coil protein 110kDa
chr19_+_44455368 3.52 ENST00000591168.1
ENST00000587682.1
ENST00000251269.5
ZNF221
zinc finger protein 221
chr8_+_1449532 3.49 ENST00000421627.2
DLGAP2
discs, large (Drosophila) homolog-associated protein 2
chr4_+_72204755 3.41 ENST00000512686.1
ENST00000340595.3
SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr5_+_118407053 3.39 ENST00000311085.8
ENST00000539542.1
DMXL1
Dmx-like 1
chr18_-_65184217 3.37 ENST00000310045.7
DSEL
dermatan sulfate epimerase-like
chr11_+_61520075 3.36 ENST00000278836.5
MYRF
myelin regulatory factor
chr1_+_51701924 3.29 ENST00000242719.3
RNF11
ring finger protein 11
chr4_+_6784401 3.26 ENST00000425103.1
ENST00000307659.5
KIAA0232
KIAA0232
chr15_-_75744014 3.22 ENST00000394947.3
ENST00000565264.1
SIN3A
SIN3 transcription regulator family member A
chr17_+_11924129 3.16 ENST00000353533.5
ENST00000415385.3
MAP2K4
mitogen-activated protein kinase kinase 4
chr16_+_30669720 3.12 ENST00000356166.6
FBRS
fibrosin
chr13_+_98086445 2.99 ENST00000245304.4
RAP2A
RAP2A, member of RAS oncogene family
chr16_+_66878814 2.99 ENST00000394069.3
CA7
carbonic anhydrase VII
chr9_+_129089088 2.97 ENST00000361171.3
ENST00000545391.1
MVB12B
multivesicular body subunit 12B
chr2_-_122407097 2.90 ENST00000409078.3
CLASP1
cytoplasmic linker associated protein 1
chr12_+_48166978 2.89 ENST00000442218.2
SLC48A1
solute carrier family 48 (heme transporter), member 1
chr17_+_46125707 2.82 ENST00000584137.1
ENST00000362042.3
ENST00000585291.1
ENST00000357480.5
NFE2L1
nuclear factor, erythroid 2-like 1
chr4_-_87281224 2.74 ENST00000395169.3
ENST00000395161.2
MAPK10
mitogen-activated protein kinase 10
chr12_-_4758159 2.73 ENST00000545990.2
AKAP3
A kinase (PRKA) anchor protein 3
chr2_-_86564776 2.71 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1
receptor accessory protein 1
chr14_+_23775971 2.49 ENST00000250405.5
BCL2L2
BCL2-like 2
chr2_+_73144604 2.44 ENST00000258106.6
EMX1
empty spiracles homeobox 1
chr8_-_80680078 2.40 ENST00000337919.5
ENST00000354724.3
HEY1
hes-related family bHLH transcription factor with YRPW motif 1
chr22_-_39151463 2.40 ENST00000405510.1
ENST00000433561.1
SUN2
Sad1 and UNC84 domain containing 2
chr9_+_136325089 2.28 ENST00000291722.7
ENST00000316948.4
ENST00000540581.1
CACFD1
calcium channel flower domain containing 1
chr6_+_45389893 2.28 ENST00000371432.3
RUNX2
runt-related transcription factor 2
chr4_+_85504075 2.25 ENST00000295887.5
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr1_-_51984908 2.25 ENST00000371730.2
EPS15
epidermal growth factor receptor pathway substrate 15
chr5_+_56111361 2.18 ENST00000399503.3
MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr14_-_93799360 2.14 ENST00000334746.5
ENST00000554565.1
ENST00000298896.3
BTBD7
BTB (POZ) domain containing 7
chr12_+_69864129 2.11 ENST00000547219.1
ENST00000299293.2
ENST00000549921.1
ENST00000550316.1
ENST00000548154.1
ENST00000547414.1
ENST00000550389.1
ENST00000550937.1
ENST00000549092.1
ENST00000550169.1
FRS2
fibroblast growth factor receptor substrate 2
chr20_-_41818373 2.10 ENST00000373187.1
ENST00000356100.2
ENST00000373184.1
ENST00000373190.1
PTPRT
protein tyrosine phosphatase, receptor type, T
chr13_+_42622781 1.98 ENST00000337343.4
ENST00000261491.5
ENST00000379274.2
DGKH
diacylglycerol kinase, eta
chr5_-_107006596 1.97 ENST00000333274.6
EFNA5
ephrin-A5
chr16_-_17564738 1.90 ENST00000261381.6
XYLT1
xylosyltransferase I
chr6_+_72596604 1.90 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
RIMS1
regulating synaptic membrane exocytosis 1
chr1_+_210001309 1.90 ENST00000491415.2
DIEXF
digestive organ expansion factor homolog (zebrafish)
chr10_+_72972281 1.88 ENST00000335350.6
UNC5B
unc-5 homolog B (C. elegans)
chr6_+_56954867 1.80 ENST00000370708.4
ENST00000370702.1
ZNF451
zinc finger protein 451
chr6_+_96463840 1.78 ENST00000302103.5
FUT9
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr2_+_241375069 1.78 ENST00000264039.2
GPC1
glypican 1
chr10_-_116286656 1.78 ENST00000428430.1
ENST00000369266.3
ENST00000392952.3
ABLIM1
actin binding LIM protein 1
chr18_+_46065393 1.71 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr18_+_29598335 1.69 ENST00000217740.3
RNF125
ring finger protein 125, E3 ubiquitin protein ligase
chr2_-_152955537 1.64 ENST00000201943.5
ENST00000539935.1
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr16_-_57513657 1.63 ENST00000566936.1
ENST00000568617.1
ENST00000567276.1
ENST00000569548.1
ENST00000569250.1
ENST00000564378.1
DOK4
docking protein 4
chr20_+_43595115 1.63 ENST00000372806.3
ENST00000396731.4
ENST00000372801.1
ENST00000499879.2
STK4
serine/threonine kinase 4
chr10_+_101419187 1.59 ENST00000370489.4
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr2_-_70995307 1.58 ENST00000264436.4
ENST00000355733.3
ENST00000447731.2
ENST00000430656.1
ENST00000413157.2
ADD2
adducin 2 (beta)
chr16_+_28875126 1.47 ENST00000359285.5
ENST00000538342.1
SH2B1
SH2B adaptor protein 1
chr10_+_64564469 1.47 ENST00000373783.1
ADO
2-aminoethanethiol (cysteamine) dioxygenase
chr12_+_74931551 1.44 ENST00000519948.2
ATXN7L3B
ataxin 7-like 3B
chr3_-_69101413 1.38 ENST00000398559.2
TMF1
TATA element modulatory factor 1
chr14_+_64932210 1.35 ENST00000394718.4
AKAP5
A kinase (PRKA) anchor protein 5
chr6_+_170102210 1.24 ENST00000439249.1
ENST00000332290.2
C6orf120
chromosome 6 open reading frame 120
chr13_+_25875662 1.23 ENST00000381736.3
ENST00000463407.1
ENST00000381718.3
NUPL1
nucleoporin like 1
chr1_-_161102421 1.18 ENST00000490843.2
ENST00000368006.3
ENST00000392188.1
ENST00000545495.1
DEDD
death effector domain containing
chr18_+_9136758 1.16 ENST00000383440.2
ENST00000262126.4
ENST00000577992.1
ANKRD12
ankyrin repeat domain 12
chr4_-_170533723 1.15 ENST00000510533.1
ENST00000439128.2
ENST00000511633.1
ENST00000512193.1
ENST00000507142.1
NEK1
NIMA-related kinase 1
chr14_-_34420259 1.14 ENST00000250457.3
ENST00000547327.2
EGLN3
egl-9 family hypoxia-inducible factor 3
chrX_+_151806637 1.13 ENST00000370306.2
GABRQ
gamma-aminobutyric acid (GABA) A receptor, theta
chr2_+_24714729 1.13 ENST00000406961.1
ENST00000405141.1
NCOA1
nuclear receptor coactivator 1
chr1_-_220445757 1.10 ENST00000358951.2
RAB3GAP2
RAB3 GTPase activating protein subunit 2 (non-catalytic)
chr9_-_19786926 1.08 ENST00000341998.2
ENST00000286344.3
SLC24A2
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr16_-_30134524 1.07 ENST00000395202.1
ENST00000395199.3
ENST00000263025.4
ENST00000322266.5
ENST00000403394.1
MAPK3
mitogen-activated protein kinase 3
chr3_-_185826855 1.07 ENST00000306376.5
ETV5
ets variant 5
chr12_-_12419703 1.03 ENST00000543091.1
ENST00000261349.4
LRP6
low density lipoprotein receptor-related protein 6
chr21_-_39288743 1.03 ENST00000609713.1
KCNJ6
potassium inwardly-rectifying channel, subfamily J, member 6
chr2_-_183903133 1.01 ENST00000361354.4
NCKAP1
NCK-associated protein 1
chr22_+_39966758 0.95 ENST00000407673.1
ENST00000401624.1
ENST00000404898.1
ENST00000402142.3
ENST00000336649.4
ENST00000400164.3
CACNA1I
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr22_-_26879734 0.95 ENST00000422379.2
ENST00000336873.5
ENST00000398145.2
HPS4
Hermansky-Pudlak syndrome 4
chr9_-_127533519 0.92 ENST00000487099.2
ENST00000344523.4
ENST00000373584.3
NR6A1
nuclear receptor subfamily 6, group A, member 1
chr5_-_141257954 0.91 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
PCDH1
protocadherin 1
chr7_-_128695147 0.90 ENST00000482320.1
ENST00000393245.1
ENST00000471234.1
TNPO3
transportin 3
chr15_+_63569731 0.89 ENST00000261879.5
APH1B
APH1B gamma secretase subunit
chr6_-_11044509 0.88 ENST00000354666.3
ELOVL2
ELOVL fatty acid elongase 2
chr3_-_46249878 0.87 ENST00000296140.3
CCR1
chemokine (C-C motif) receptor 1
chr14_+_45553296 0.87 ENST00000355765.6
ENST00000553605.1
PRPF39
pre-mRNA processing factor 39
chr14_+_56585048 0.86 ENST00000267460.4
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr19_+_18747775 0.84 ENST00000300976.4
ENST00000595182.1
ENST00000599006.1
KLHL26
kelch-like family member 26
chr10_-_115904361 0.84 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chr9_+_140772226 0.83 ENST00000277551.2
ENST00000371372.1
ENST00000277549.5
ENST00000371363.1
ENST00000371357.1
ENST00000371355.4
CACNA1B
calcium channel, voltage-dependent, N type, alpha 1B subunit
chr12_-_117319236 0.83 ENST00000257572.5
HRK
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr1_+_200708671 0.81 ENST00000358823.2
CAMSAP2
calmodulin regulated spectrin-associated protein family, member 2
chr4_+_3768075 0.80 ENST00000509482.1
ENST00000330055.5
ADRA2C
adrenoceptor alpha 2C
chr8_-_116681221 0.80 ENST00000395715.3
TRPS1
trichorhinophalangeal syndrome I
chr8_+_26240414 0.80 ENST00000380629.2
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr14_+_101193164 0.79 ENST00000341267.4
DLK1
delta-like 1 homolog (Drosophila)
chr14_+_59104741 0.78 ENST00000395153.3
ENST00000335867.4
DACT1
dishevelled-binding antagonist of beta-catenin 1
chr15_+_79724858 0.75 ENST00000305428.3
KIAA1024
KIAA1024
chr11_+_63606373 0.74 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MARK2
MAP/microtubule affinity-regulating kinase 2
chr9_-_80646374 0.73 ENST00000286548.4
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr22_-_39268308 0.73 ENST00000407418.3
CBX6
chromobox homolog 6
chr13_-_31736027 0.72 ENST00000380406.5
ENST00000320027.5
ENST00000380405.4
HSPH1
heat shock 105kDa/110kDa protein 1
chr17_+_5031687 0.71 ENST00000250066.6
ENST00000304328.5
USP6
ubiquitin specific peptidase 6 (Tre-2 oncogene)
chr12_-_56583332 0.70 ENST00000347471.4
ENST00000267064.4
ENST00000394023.3
SMARCC2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr3_+_29322803 0.68 ENST00000396583.3
ENST00000383767.2
RBMS3
RNA binding motif, single stranded interacting protein 3
chr1_+_77333117 0.67 ENST00000477717.1
ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr10_+_60272814 0.65 ENST00000373886.3
BICC1
bicaudal C homolog 1 (Drosophila)
chr20_+_43374421 0.62 ENST00000372861.3
KCNK15
potassium channel, subfamily K, member 15
chr11_-_47198380 0.59 ENST00000419701.2
ENST00000526342.1
ENST00000528444.1
ENST00000530596.1
ENST00000525398.1
ENST00000319543.6
ENST00000426335.2
ENST00000527927.1
ENST00000525314.1
ARFGAP2
ADP-ribosylation factor GTPase activating protein 2
chr5_-_137368708 0.58 ENST00000033079.3
FAM13B
family with sequence similarity 13, member B
chr2_-_54087066 0.56 ENST00000394705.2
ENST00000352846.3
ENST00000406625.2
GPR75
GPR75-ASB3
ASB3
G protein-coupled receptor 75
GPR75-ASB3 readthrough
Ankyrin repeat and SOCS box protein 3
chr6_+_50786414 0.55 ENST00000344788.3
ENST00000393655.3
ENST00000263046.4
TFAP2B
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr9_+_37800758 0.50 ENST00000242323.7
DCAF10
DDB1 and CUL4 associated factor 10
chr5_-_43313574 0.49 ENST00000325110.6
ENST00000433297.2
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr21_-_34144157 0.48 ENST00000331923.4
PAXBP1
PAX3 and PAX7 binding protein 1
chr6_+_37225540 0.46 ENST00000373491.3
TBC1D22B
TBC1 domain family, member 22B
chr17_+_58677539 0.45 ENST00000305921.3
PPM1D
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr2_+_45878790 0.45 ENST00000306156.3
PRKCE
protein kinase C, epsilon
chr17_-_73775839 0.43 ENST00000592643.1
ENST00000591890.1
ENST00000587171.1
ENST00000254810.4
ENST00000589599.1
H3F3B
H3 histone, family 3B (H3.3B)
chr9_-_124989804 0.43 ENST00000373755.2
ENST00000373754.2
LHX6
LIM homeobox 6
chr10_+_11206925 0.41 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CELF2
CUGBP, Elav-like family member 2
chr15_+_33603147 0.41 ENST00000415757.3
ENST00000389232.4
RYR3
ryanodine receptor 3
chr6_-_108279369 0.38 ENST00000369002.4
SEC63
SEC63 homolog (S. cerevisiae)
chr2_+_242577027 0.33 ENST00000402096.1
ENST00000404914.3
ATG4B
autophagy related 4B, cysteine peptidase
chr12_-_81331697 0.32 ENST00000552864.1
LIN7A
lin-7 homolog A (C. elegans)
chr1_-_93426998 0.31 ENST00000370310.4
FAM69A
family with sequence similarity 69, member A
chr13_-_49107303 0.31 ENST00000344532.3
RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr2_-_172750733 0.30 ENST00000392592.4
ENST00000422440.2
SLC25A12
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr9_+_129567282 0.29 ENST00000449886.1
ENST00000373464.4
ENST00000450858.1
ZBTB43
zinc finger and BTB domain containing 43
chr5_+_176560742 0.27 ENST00000439151.2
NSD1
nuclear receptor binding SET domain protein 1
chr12_+_130646999 0.26 ENST00000539839.1
ENST00000229030.4
FZD10
frizzled family receptor 10
chr22_-_22863466 0.26 ENST00000406426.1
ENST00000360412.2
ZNF280B
zinc finger protein 280B
chr9_-_73736511 0.26 ENST00000377110.3
ENST00000377111.2
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr3_+_38495333 0.23 ENST00000352511.4
ACVR2B
activin A receptor, type IIB
chr16_-_15736953 0.21 ENST00000548025.1
ENST00000551742.1
ENST00000602337.1
ENST00000344181.3
ENST00000396368.3
KIAA0430
KIAA0430
chr4_+_177241094 0.20 ENST00000503362.1
SPCS3
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chr3_-_52931557 0.18 ENST00000504329.1
ENST00000355083.5
TMEM110-MUSTN1
TMEM110
TMEM110-MUSTN1 readthrough
transmembrane protein 110
chr22_+_41697520 0.18 ENST00000352645.4
ZC3H7B
zinc finger CCCH-type containing 7B
chrX_+_16804544 0.17 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chr4_-_68620053 0.14 ENST00000420975.2
ENST00000226413.4
GNRHR
gonadotropin-releasing hormone receptor
chr17_-_79885576 0.11 ENST00000574686.1
ENST00000357736.4
MAFG
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr6_+_37321748 0.10 ENST00000373479.4
ENST00000394443.4
RNF8
ring finger protein 8, E3 ubiquitin protein ligase
chr13_-_40177261 0.09 ENST00000379589.3
LHFP
lipoma HMGIC fusion partner
chr22_-_31688431 0.01 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr14_-_76127519 0.01 ENST00000256319.6
C14orf1
chromosome 14 open reading frame 1

Network of associatons between targets according to the STRING database.

First level regulatory network of AGCCCUU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 11.4 GO:1902948 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
3.0 21.3 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
2.9 28.8 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
2.8 8.5 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
2.8 14.1 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
2.6 7.8 GO:1902809 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
2.4 7.2 GO:0060168 regulation of axon diameter(GO:0031133) positive regulation of adenosine receptor signaling pathway(GO:0060168)
1.8 8.8 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
1.7 5.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
1.6 9.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
1.3 10.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
1.1 3.2 GO:0051595 response to methylglyoxal(GO:0051595)
1.1 6.4 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
1.0 1.0 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.9 5.4 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.9 3.6 GO:0032053 ciliary basal body organization(GO:0032053)
0.7 2.1 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.6 6.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.6 2.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.6 2.4 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.6 3.0 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.5 3.8 GO:0046465 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.5 3.7 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.5 21.6 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.4 4.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.4 18.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.4 2.4 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.4 9.3 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.4 1.1 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.4 3.4 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.4 2.9 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.4 14.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.4 2.5 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.4 1.8 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.3 2.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.3 1.6 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.3 2.3 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.3 2.3 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.3 1.0 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.3 7.0 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.3 3.0 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.3 1.5 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.3 2.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.3 3.4 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.3 1.4 GO:2000843 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.3 1.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.3 2.9 GO:0015886 heme transport(GO:0015886)
0.3 1.8 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633)
0.2 4.2 GO:0071318 cellular response to ATP(GO:0071318)
0.2 1.1 GO:1903059 regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061)
0.2 1.1 GO:0000189 MAPK import into nucleus(GO:0000189)
0.2 0.8 GO:0032811 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.2 2.0 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 3.0 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.2 13.2 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.2 4.5 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 1.8 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 1.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.7 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.1 0.5 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 3.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.8 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.8 GO:1900107 regulation of nodal signaling pathway(GO:1900107)
0.1 4.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 1.5 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.1 0.3 GO:0051697 protein delipidation(GO:0051697)
0.1 10.9 GO:0014902 myotube differentiation(GO:0014902)
0.1 1.0 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 4.1 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.1 1.6 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.1 0.9 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.9 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.9 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 3.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 2.8 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 0.3 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 9.3 GO:0006970 response to osmotic stress(GO:0006970)
0.1 0.7 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.1 0.5 GO:0072501 cellular divalent inorganic anion homeostasis(GO:0072501)
0.1 0.4 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 3.4 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 2.2 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.1 0.5 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.1 0.2 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of NFAT protein import into nucleus(GO:0051533) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.8 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.5 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 1.6 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 0.9 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.1 2.0 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 3.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 5.8 GO:0050868 negative regulation of T cell activation(GO:0050868)
0.1 1.0 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 1.9 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 1.1 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.4 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 1.1 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.8 GO:0048265 response to pain(GO:0048265)
0.0 0.3 GO:0034770 regulation of histone H3-K36 methylation(GO:0000414) histone H4-K20 methylation(GO:0034770)
0.0 0.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 1.6 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 3.5 GO:0007270 neuron-neuron synaptic transmission(GO:0007270)
0.0 0.8 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.7 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 1.0 GO:0010107 potassium ion import(GO:0010107)
0.0 1.5 GO:0045840 positive regulation of mitotic nuclear division(GO:0045840)
0.0 5.2 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 11.4 GO:0048232 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 0.3 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 1.7 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.7 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 1.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.2 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.9 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 9.9 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
2.8 14.1 GO:0045298 tubulin complex(GO:0045298)
2.4 9.6 GO:1990246 uniplex complex(GO:1990246)
1.1 3.4 GO:0043291 RAVE complex(GO:0043291)
1.0 20.4 GO:0033268 node of Ranvier(GO:0033268)
1.0 16.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.9 8.5 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.8 11.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.7 4.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.6 3.8 GO:0005927 muscle tendon junction(GO:0005927)
0.6 6.3 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.5 10.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.5 2.9 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.4 3.0 GO:0000813 ESCRT I complex(GO:0000813)
0.4 5.1 GO:0060077 inhibitory synapse(GO:0060077)
0.4 4.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.3 1.0 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.3 14.7 GO:0048786 presynaptic active zone(GO:0048786)
0.3 6.4 GO:0044295 axonal growth cone(GO:0044295)
0.3 4.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.3 9.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.3 5.7 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.2 2.7 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 16.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 7.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 1.0 GO:0031085 BLOC-3 complex(GO:0031085)
0.2 2.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 2.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 2.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 3.2 GO:0016580 Sin3 complex(GO:0016580)
0.1 2.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 3.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 32.9 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 0.7 GO:0097427 microtubule bundle(GO:0097427)
0.1 2.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 1.0 GO:0031209 SCAR complex(GO:0031209)
0.1 7.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 0.9 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 27.2 GO:0045121 membrane raft(GO:0045121)
0.1 1.9 GO:0032040 small-subunit processome(GO:0032040)
0.1 0.9 GO:0000243 commitment complex(GO:0000243)
0.1 0.8 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 9.1 GO:0001650 fibrillar center(GO:0001650)
0.1 1.1 GO:0000242 pericentriolar material(GO:0000242)
0.1 9.3 GO:0005875 microtubule associated complex(GO:0005875)
0.1 0.8 GO:1990752 microtubule end(GO:1990752)
0.0 7.0 GO:0055037 recycling endosome(GO:0055037)
0.0 3.6 GO:0005814 centriole(GO:0005814)
0.0 2.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.7 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.7 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 2.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 5.1 GO:0005768 endosome(GO:0005768)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.6 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 3.6 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.6 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 3.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 6.2 GO:0016607 nuclear speck(GO:0016607)
0.0 0.7 GO:0031519 PcG protein complex(GO:0031519)
0.0 2.9 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 24.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
3.8 23.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
3.5 14.1 GO:0099609 microtubule lateral binding(GO:0099609)
3.4 16.9 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
3.3 9.9 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
1.4 4.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
1.4 4.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
1.3 5.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
1.1 3.4 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
1.0 8.2 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.8 6.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.8 2.3 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.7 2.9 GO:0043515 kinetochore binding(GO:0043515)
0.7 11.4 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.7 2.0 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.6 10.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.6 1.9 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.6 3.7 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.6 2.4 GO:0035939 microsatellite binding(GO:0035939)
0.6 2.9 GO:0070097 delta-catenin binding(GO:0070097)
0.5 15.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.5 13.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.4 7.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.4 0.4 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.4 1.8 GO:0061665 SUMO ligase activity(GO:0061665)
0.4 5.4 GO:0045499 chemorepellent activity(GO:0045499)
0.3 1.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.3 1.9 GO:0034511 U3 snoRNA binding(GO:0034511)
0.3 0.9 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.3 2.9 GO:0015232 heme transporter activity(GO:0015232)
0.3 0.8 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.2 15.7 GO:0043621 protein self-association(GO:0043621)
0.2 0.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 1.8 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.2 5.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 1.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 4.0 GO:0017091 AU-rich element binding(GO:0017091)
0.2 4.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 3.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 3.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 6.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 2.4 GO:0043495 protein anchor(GO:0043495)
0.1 6.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.0 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.1 2.5 GO:0051400 BH domain binding(GO:0051400)
0.1 0.7 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 9.4 GO:0005262 calcium channel activity(GO:0005262)
0.1 0.5 GO:0035276 ethanol binding(GO:0035276)
0.1 1.3 GO:0008179 adenylate cyclase binding(GO:0008179) protein phosphatase 2B binding(GO:0030346)
0.1 2.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 19.0 GO:0044325 ion channel binding(GO:0044325)
0.1 3.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 1.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 1.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 1.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 1.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 2.4 GO:0030507 spectrin binding(GO:0030507)
0.1 2.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.9 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 2.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 2.7 GO:0051018 protein kinase A binding(GO:0051018)
0.1 4.5 GO:0002039 p53 binding(GO:0002039)
0.1 6.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 2.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 7.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 18.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.1 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.8 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 4.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 2.3 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 6.1 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.5 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 1.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.9 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.4 GO:0036002 pre-mRNA binding(GO:0036002)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 14.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.4 24.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.3 19.0 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.3 1.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.3 7.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.2 13.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 10.4 PID AURORA A PATHWAY Aurora A signaling
0.1 7.6 PID ARF6 PATHWAY Arf6 signaling events
0.1 22.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 5.1 PID AURORA B PATHWAY Aurora B signaling
0.1 5.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 1.6 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 7.9 PID SHP2 PATHWAY SHP2 signaling
0.1 2.8 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 7.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 4.7 PID NOTCH PATHWAY Notch signaling pathway
0.1 1.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.8 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.1 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.5 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 9.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.5 16.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.4 14.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3 5.9 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.3 8.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 3.8 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 5.8 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2 3.0 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 8.3 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 4.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 6.3 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 8.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.9 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 5.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 3.9 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 1.9 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 4.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 3.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 2.3 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 0.9 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 0.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.2 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 1.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.8 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 1.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 2.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 2.0 REACTOME NEGATIVE REGULATION OF FGFR SIGNALING Genes involved in Negative regulation of FGFR signaling
0.0 0.9 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.8 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 2.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 4.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 8.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.2 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 2.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 2.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 3.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases