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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for BARX1

Z-value: 0.78

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Transcription factors associated with BARX1

Gene Symbol Gene ID Gene Info
BARX1
ENSG00000131668.9 BARX homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BARX1hg19_v2_chr9_-_96717654_96717666-0.221.4e-03Click!

Activity profile of BARX1 motif

Sorted Z-values of BARX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_159848807 21.91 ENST00000352433.5
PTTG1
pituitary tumor-transforming 1
chr1_-_95391315 17.58 ENST00000545882.1
ENST00000415017.1
CNN3
calponin 3, acidic
chr12_-_10978957 16.94 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr7_+_107220660 16.84 ENST00000465919.1
ENST00000445771.2
ENST00000479917.1
ENST00000421217.1
ENST00000457837.1
BCAP29
B-cell receptor-associated protein 29
chr1_-_197115818 16.64 ENST00000367409.4
ENST00000294732.7
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr2_-_106054952 16.64 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
FHL2
four and a half LIM domains 2
chr16_-_66864806 15.97 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
NAE1
NEDD8 activating enzyme E1 subunit 1
chr2_-_58468437 15.75 ENST00000403676.1
ENST00000427708.2
ENST00000403295.3
ENST00000446381.1
ENST00000417361.1
ENST00000233741.4
ENST00000402135.3
ENST00000540646.1
ENST00000449070.1
FANCL
Fanconi anemia, complementation group L
chr12_+_21207503 15.71 ENST00000545916.1
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr17_-_8113542 15.41 ENST00000578549.1
ENST00000535053.1
ENST00000582368.1
AURKB
aurora kinase B
chr3_-_149093499 15.02 ENST00000472441.1
TM4SF1
transmembrane 4 L six family member 1
chr12_-_52911718 14.56 ENST00000548409.1
KRT5
keratin 5
chr10_+_62538089 14.56 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
CDK1
cyclin-dependent kinase 1
chr12_+_104609550 14.09 ENST00000525566.1
ENST00000429002.2
TXNRD1
thioredoxin reductase 1
chr5_+_140762268 13.84 ENST00000518325.1
PCDHGA7
protocadherin gamma subfamily A, 7
chr3_-_64009658 13.60 ENST00000394431.2
PSMD6
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr20_+_11898507 13.52 ENST00000378226.2
BTBD3
BTB (POZ) domain containing 3
chr7_+_32996997 13.45 ENST00000242209.4
ENST00000538336.1
ENST00000538443.1
FKBP9
FK506 binding protein 9, 63 kDa
chrX_+_12809463 12.56 ENST00000380663.3
ENST00000380668.5
ENST00000398491.2
ENST00000489404.1
PRPS2
phosphoribosyl pyrophosphate synthetase 2
chr8_-_141774467 12.52 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
PTK2
protein tyrosine kinase 2
chr4_+_88343952 12.41 ENST00000440591.2
NUDT9
nudix (nucleoside diphosphate linked moiety X)-type motif 9
chrX_+_21958674 12.30 ENST00000404933.2
SMS
spermine synthase
chr15_-_72523924 12.15 ENST00000566809.1
ENST00000567087.1
ENST00000569050.1
ENST00000568883.1
PKM
pyruvate kinase, muscle
chr10_-_95242044 12.10 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
MYOF
myoferlin
chr2_+_130737223 11.90 ENST00000410061.2
RAB6C
RAB6C, member RAS oncogene family
chr3_+_160117087 11.87 ENST00000357388.3
SMC4
structural maintenance of chromosomes 4
chr1_-_145826450 11.83 ENST00000462900.2
GPR89A
G protein-coupled receptor 89A
chr3_+_138340049 11.73 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr10_-_95241951 11.51 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
MYOF
myoferlin
chr14_+_55595762 11.17 ENST00000254301.9
LGALS3
lectin, galactoside-binding, soluble, 3
chr1_-_21377447 10.99 ENST00000374937.3
ENST00000264211.8
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr2_+_231921574 10.83 ENST00000308696.6
ENST00000373635.4
ENST00000440838.1
ENST00000409643.1
PSMD1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr16_-_29934558 10.81 ENST00000568995.1
ENST00000566413.1
KCTD13
potassium channel tetramerization domain containing 13
chr15_-_59949693 10.73 ENST00000396063.1
ENST00000396064.3
ENST00000484743.1
ENST00000559706.1
ENST00000396060.2
GTF2A2
general transcription factor IIA, 2, 12kDa
chrX_-_15511438 10.72 ENST00000380420.5
PIR
pirin (iron-binding nuclear protein)
chr4_+_169418195 10.61 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr1_-_150208363 10.54 ENST00000436748.2
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr3_-_185538849 10.47 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr3_-_186524234 10.45 ENST00000418288.1
ENST00000296273.2
RFC4
replication factor C (activator 1) 4, 37kDa
chr1_+_220267429 10.29 ENST00000366922.1
ENST00000302637.5
IARS2
isoleucyl-tRNA synthetase 2, mitochondrial
chr8_+_30244580 10.27 ENST00000523115.1
ENST00000519647.1
RBPMS
RNA binding protein with multiple splicing
chr6_+_63921399 10.05 ENST00000356170.3
FKBP1C
FK506 binding protein 1C
chr3_+_138340067 9.81 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr15_-_59949667 9.79 ENST00000396061.1
GTF2A2
general transcription factor IIA, 2, 12kDa
chr10_+_70748487 9.72 ENST00000361983.4
KIAA1279
KIAA1279
chr22_-_19466732 9.71 ENST00000263202.10
ENST00000360834.4
UFD1L
ubiquitin fusion degradation 1 like (yeast)
chr19_-_55660561 9.51 ENST00000587758.1
ENST00000356783.5
ENST00000291901.8
ENST00000588426.1
ENST00000588147.1
ENST00000536926.1
ENST00000588981.1
TNNT1
troponin T type 1 (skeletal, slow)
chr3_-_123512688 9.39 ENST00000475616.1
MYLK
myosin light chain kinase
chr22_-_19466683 9.38 ENST00000399523.1
ENST00000421968.2
ENST00000447868.1
UFD1L
ubiquitin fusion degradation 1 like (yeast)
chr1_+_110546700 9.34 ENST00000359172.3
ENST00000393614.4
AHCYL1
adenosylhomocysteinase-like 1
chr1_-_150208412 9.33 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr5_+_167913450 9.27 ENST00000231572.3
ENST00000538719.1
RARS
arginyl-tRNA synthetase
chr6_-_13814663 9.21 ENST00000359495.2
ENST00000379170.4
MCUR1
mitochondrial calcium uniporter regulator 1
chr2_+_172544294 9.20 ENST00000358002.6
ENST00000435234.1
ENST00000443458.1
ENST00000412370.1
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr4_+_41540160 9.03 ENST00000503057.1
ENST00000511496.1
LIMCH1
LIM and calponin homology domains 1
chr15_-_56757329 9.01 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr22_-_36220420 8.92 ENST00000473487.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr19_-_14945933 8.91 ENST00000322301.3
OR7A5
olfactory receptor, family 7, subfamily A, member 5
chr6_-_131277510 8.85 ENST00000525193.1
ENST00000527659.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr13_+_48611665 8.84 ENST00000258662.2
NUDT15
nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr7_+_107220422 8.74 ENST00000005259.4
BCAP29
B-cell receptor-associated protein 29
chr1_-_150208498 8.72 ENST00000314136.8
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr16_-_10652993 8.67 ENST00000536829.1
EMP2
epithelial membrane protein 2
chr1_-_155904187 8.58 ENST00000368321.3
ENST00000368320.3
KIAA0907
KIAA0907
chr1_-_150208291 8.54 ENST00000533654.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chrX_-_41449204 8.48 ENST00000378179.3
CASK
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr1_-_6420737 8.35 ENST00000541130.1
ENST00000377845.3
ACOT7
acyl-CoA thioesterase 7
chr1_-_160492994 8.31 ENST00000368055.1
ENST00000368057.3
ENST00000368059.3
SLAMF6
SLAM family member 6
chr9_+_108463234 8.23 ENST00000374688.1
TMEM38B
transmembrane protein 38B
chr17_+_18601299 8.20 ENST00000572555.1
ENST00000395902.3
ENST00000449552.2
TRIM16L
tripartite motif containing 16-like
chr16_-_21868978 8.17 ENST00000357370.5
ENST00000451409.1
ENST00000341400.7
ENST00000518761.4
NPIPB4
nuclear pore complex interacting protein family, member B4
chr6_-_114194483 8.14 ENST00000434296.2
RP1-249H1.4
RP1-249H1.4
chr14_+_73563735 8.02 ENST00000532192.1
RBM25
RNA binding motif protein 25
chr16_-_21436459 7.96 ENST00000448012.2
ENST00000504841.2
ENST00000419180.2
NPIPB3
nuclear pore complex interacting protein family, member B3
chr14_+_89060739 7.90 ENST00000318308.6
ZC3H14
zinc finger CCCH-type containing 14
chr8_+_54764346 7.89 ENST00000297313.3
ENST00000344277.6
RGS20
regulator of G-protein signaling 20
chrX_-_13835147 7.84 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chrX_-_134156502 7.84 ENST00000391440.1
FAM127C
family with sequence similarity 127, member C
chr12_-_71551652 7.79 ENST00000546561.1
TSPAN8
tetraspanin 8
chr6_-_75960024 7.63 ENST00000370081.2
COX7A2
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
chr2_+_169312350 7.57 ENST00000305747.6
CERS6
ceramide synthase 6
chr16_+_14802801 7.56 ENST00000526520.1
ENST00000531598.2
NPIPA3
nuclear pore complex interacting protein family, member A3
chr22_+_19467261 7.37 ENST00000455750.1
ENST00000437685.2
ENST00000263201.1
ENST00000404724.3
CDC45
cell division cycle 45
chr12_+_19282643 7.31 ENST00000317589.4
ENST00000355397.3
ENST00000359180.3
ENST00000309364.4
ENST00000540972.1
ENST00000429027.2
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr12_+_123237321 7.17 ENST00000280557.6
ENST00000455982.2
DENR
density-regulated protein
chr11_-_10828892 7.16 ENST00000525681.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr19_-_47349395 7.15 ENST00000597020.1
AP2S1
adaptor-related protein complex 2, sigma 1 subunit
chr13_+_98612446 7.14 ENST00000496368.1
ENST00000421861.2
ENST00000357602.3
IPO5
importin 5
chr10_-_72648541 7.08 ENST00000299299.3
PCBD1
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
chr7_-_105752971 7.08 ENST00000011473.2
SYPL1
synaptophysin-like 1
chr20_+_34129770 7.02 ENST00000348547.2
ENST00000357394.4
ENST00000447986.1
ENST00000279052.6
ENST00000416206.1
ENST00000411577.1
ENST00000413587.1
ERGIC3
ERGIC and golgi 3
chr8_-_87526561 7.01 ENST00000523911.1
RMDN1
regulator of microtubule dynamics 1
chr16_+_22524844 7.01 ENST00000538606.1
ENST00000424340.1
ENST00000517539.1
ENST00000528249.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr9_-_69229650 6.87 ENST00000416428.1
CBWD6
COBW domain containing 6
chr1_-_246729544 6.74 ENST00000544618.1
ENST00000366514.4
TFB2M
transcription factor B2, mitochondrial
chr6_-_56819385 6.69 ENST00000370754.5
ENST00000449297.2
DST
dystonin
chr5_-_55412774 6.67 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr1_-_43855444 6.66 ENST00000372455.4
MED8
mediator complex subunit 8
chr9_-_70465758 6.64 ENST00000489273.1
CBWD5
COBW domain containing 5
chr2_+_237994519 6.61 ENST00000392008.2
ENST00000409334.1
ENST00000409629.1
COPS8
COP9 signalosome subunit 8
chr5_+_72143988 6.56 ENST00000506351.2
TNPO1
transportin 1
chr5_+_65222384 6.52 ENST00000380943.2
ENST00000416865.2
ENST00000380939.2
ENST00000380936.1
ENST00000380935.1
ERBB2IP
erbb2 interacting protein
chr16_-_29415350 6.52 ENST00000524087.1
NPIPB11
nuclear pore complex interacting protein family, member B11
chr4_+_113568207 6.48 ENST00000511529.1
LARP7
La ribonucleoprotein domain family, member 7
chr10_+_92631709 6.48 ENST00000413330.1
ENST00000277882.3
RPP30
ribonuclease P/MRP 30kDa subunit
chr12_+_20968608 6.47 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
LST3
SLCO1B3
SLCO1B7
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr2_+_242289502 6.40 ENST00000451310.1
SEPT2
septin 2
chr3_+_8543393 6.39 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1
LIM and cysteine-rich domains 1
chr8_+_132952112 6.36 ENST00000520362.1
ENST00000519656.1
EFR3A
EFR3 homolog A (S. cerevisiae)
chrX_-_114253536 6.34 ENST00000371936.1
IL13RA2
interleukin 13 receptor, alpha 2
chr20_-_47804894 6.33 ENST00000371828.3
ENST00000371856.2
ENST00000360426.4
ENST00000347458.5
ENST00000340954.7
ENST00000371802.1
ENST00000371792.1
ENST00000437404.2
STAU1
staufen double-stranded RNA binding protein 1
chr2_-_175711133 6.29 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chr1_+_73771844 6.26 ENST00000440762.1
ENST00000444827.1
ENST00000415686.1
ENST00000411903.1
RP4-598G3.1
RP4-598G3.1
chrX_+_133733457 6.23 ENST00000440614.1
RP11-308B5.2
RP11-308B5.2
chr3_-_176914238 6.16 ENST00000430069.1
ENST00000428970.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr7_+_16793160 6.12 ENST00000262067.4
TSPAN13
tetraspanin 13
chr14_+_55595960 6.08 ENST00000554715.1
LGALS3
lectin, galactoside-binding, soluble, 3
chr15_-_66816853 6.02 ENST00000568588.1
RPL4
ribosomal protein L4
chr1_-_54411255 5.91 ENST00000371377.3
HSPB11
heat shock protein family B (small), member 11
chr16_-_29517141 5.86 ENST00000550665.1
RP11-231C14.4
Uncharacterized protein
chr12_+_20963632 5.78 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr8_-_101719159 5.73 ENST00000520868.1
ENST00000522658.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr1_-_21377383 5.69 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr14_-_75643296 5.68 ENST00000303575.4
TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr2_+_11696464 5.66 ENST00000234142.5
GREB1
growth regulation by estrogen in breast cancer 1
chr20_-_45984401 5.65 ENST00000311275.7
ZMYND8
zinc finger, MYND-type containing 8
chr14_-_50319758 5.62 ENST00000298310.5
NEMF
nuclear export mediator factor
chr4_-_17513851 5.60 ENST00000281243.5
QDPR
quinoid dihydropteridine reductase
chr12_-_121019165 5.56 ENST00000341039.2
ENST00000357500.4
POP5
processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
chr3_+_25831567 5.55 ENST00000280701.3
ENST00000420173.2
OXSM
3-oxoacyl-ACP synthase, mitochondrial
chr7_+_93551011 5.55 ENST00000248564.5
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr8_+_87526645 5.52 ENST00000521271.1
ENST00000523072.1
ENST00000523001.1
ENST00000520814.1
ENST00000517771.1
CPNE3
copine III
chr5_-_43557791 5.51 ENST00000338972.4
ENST00000511321.1
ENST00000515338.1
PAIP1
poly(A) binding protein interacting protein 1
chr15_-_52587945 5.50 ENST00000443683.2
ENST00000558479.1
ENST00000261839.7
MYO5C
myosin VC
chr8_-_109260897 5.38 ENST00000521297.1
ENST00000519030.1
ENST00000521440.1
ENST00000518345.1
ENST00000519627.1
ENST00000220849.5
EIF3E
eukaryotic translation initiation factor 3, subunit E
chr2_+_109335929 5.37 ENST00000283195.6
RANBP2
RAN binding protein 2
chr6_-_2971429 5.33 ENST00000380529.1
SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr7_-_105752651 5.30 ENST00000470347.1
ENST00000455385.2
SYPL1
synaptophysin-like 1
chr5_-_16742330 5.26 ENST00000505695.1
ENST00000427430.2
MYO10
myosin X
chrX_-_114252193 5.26 ENST00000243213.1
IL13RA2
interleukin 13 receptor, alpha 2
chr17_-_41132410 5.26 ENST00000409446.3
ENST00000453594.1
ENST00000409399.1
ENST00000421990.2
PTGES3L
PTGES3L-AARSD1
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr3_+_179280668 5.23 ENST00000429709.2
ENST00000450518.2
ENST00000392662.1
ENST00000490364.1
ACTL6A
actin-like 6A
chr11_-_102401469 5.23 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr22_+_19466980 5.21 ENST00000407835.1
ENST00000438587.1
CDC45
cell division cycle 45
chr6_-_52859046 5.10 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
GSTA4
glutathione S-transferase alpha 4
chr5_+_65222299 5.10 ENST00000284037.5
ERBB2IP
erbb2 interacting protein
chr20_+_56964253 5.10 ENST00000395802.3
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr7_-_72993033 5.09 ENST00000305632.5
TBL2
transducin (beta)-like 2
chr11_+_20409070 5.05 ENST00000331079.6
PRMT3
protein arginine methyltransferase 3
chr4_-_69817481 5.03 ENST00000251566.4
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr1_-_165668100 5.00 ENST00000354775.4
ALDH9A1
aldehyde dehydrogenase 9 family, member A1
chr18_+_21529811 4.94 ENST00000588004.1
LAMA3
laminin, alpha 3
chr11_+_57480046 4.94 ENST00000378312.4
ENST00000278422.4
TMX2
thioredoxin-related transmembrane protein 2
chr6_+_37321823 4.92 ENST00000487950.1
ENST00000469731.1
RNF8
ring finger protein 8, E3 ubiquitin protein ligase
chr17_+_7155819 4.92 ENST00000570322.1
ENST00000576496.1
ENST00000574841.2
ELP5
elongator acetyltransferase complex subunit 5
chr19_+_41281416 4.89 ENST00000597140.1
MIA
melanoma inhibitory activity
chr5_+_140797296 4.78 ENST00000398594.2
PCDHGB7
protocadherin gamma subfamily B, 7
chr14_+_102276209 4.76 ENST00000445439.3
ENST00000334743.5
ENST00000557095.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr1_+_16083154 4.76 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr12_-_120884175 4.76 ENST00000546954.1
TRIAP1
TP53 regulated inhibitor of apoptosis 1
chr9_-_21974820 4.74 ENST00000579122.1
ENST00000498124.1
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr14_+_89060749 4.73 ENST00000555900.1
ENST00000406216.3
ENST00000557737.1
ZC3H14
zinc finger CCCH-type containing 14
chr1_-_115292591 4.72 ENST00000438362.2
CSDE1
cold shock domain containing E1, RNA-binding
chr12_+_20963647 4.71 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr8_-_101718991 4.68 ENST00000517990.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr3_-_130465604 4.66 ENST00000356763.3
PIK3R4
phosphoinositide-3-kinase, regulatory subunit 4
chr16_+_22501658 4.65 ENST00000415833.2
NPIPB5
nuclear pore complex interacting protein family, member B5
chr11_+_93479588 4.61 ENST00000526335.1
C11orf54
chromosome 11 open reading frame 54
chr2_-_8723918 4.59 ENST00000454224.1
AC011747.4
AC011747.4
chr5_+_140743859 4.57 ENST00000518069.1
PCDHGA5
protocadherin gamma subfamily A, 5
chr6_+_123100620 4.57 ENST00000368444.3
FABP7
fatty acid binding protein 7, brain
chr12_+_50794592 4.53 ENST00000293618.8
ENST00000429001.3
ENST00000548174.1
ENST00000548697.1
ENST00000548993.1
ENST00000398473.2
ENST00000522085.1
ENST00000518444.1
ENST00000551886.1
LARP4
La ribonucleoprotein domain family, member 4
chr5_-_141392538 4.51 ENST00000503794.1
ENST00000510194.1
ENST00000504424.1
ENST00000513454.1
ENST00000458112.2
ENST00000542860.1
ENST00000503229.1
ENST00000500692.2
ENST00000311337.6
ENST00000504139.1
ENST00000505689.1
GNPDA1
glucosamine-6-phosphate deaminase 1
chrX_+_54466829 4.51 ENST00000375151.4
TSR2
TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
chr9_+_35161998 4.51 ENST00000396787.1
ENST00000378495.3
ENST00000378496.4
UNC13B
unc-13 homolog B (C. elegans)
chr5_-_9630463 4.50 ENST00000382492.2
TAS2R1
taste receptor, type 2, member 1
chr7_+_107531580 4.48 ENST00000537148.1
ENST00000440410.1
ENST00000437604.2
DLD
dihydrolipoamide dehydrogenase
chr2_+_109237717 4.36 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr7_+_134576151 4.35 ENST00000393118.2
CALD1
caldesmon 1
chr9_-_21202204 4.35 ENST00000239347.3
IFNA7
interferon, alpha 7
chr2_-_74618964 4.34 ENST00000417090.1
ENST00000409868.1
DCTN1
dynactin 1
chr7_+_134576317 4.32 ENST00000424922.1
ENST00000495522.1
CALD1
caldesmon 1
chr16_+_16434185 4.31 ENST00000524823.2
AC138969.4
Protein PKD1P1
chr7_-_64023441 4.29 ENST00000309683.6
ZNF680
zinc finger protein 680
chr5_-_125930929 4.29 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr8_+_107670064 4.27 ENST00000312046.6
OXR1
oxidation resistance 1
chr1_-_236767779 4.20 ENST00000366579.1
ENST00000366582.3
ENST00000366581.2
HEATR1
HEAT repeat containing 1
chr12_-_50290839 4.19 ENST00000552863.1
FAIM2
Fas apoptotic inhibitory molecule 2
chrX_-_109590174 4.16 ENST00000372054.1
GNG5P2
guanine nucleotide binding protein (G protein), gamma 5 pseudogene 2
chr11_-_86383650 4.13 ENST00000526944.1
ENST00000530335.1
ENST00000543262.1
ENST00000524826.1
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr19_-_53662257 4.11 ENST00000599096.1
ENST00000334197.7
ENST00000597183.1
ENST00000601804.1
ENST00000601469.2
ENST00000452676.2
ZNF347
zinc finger protein 347
chr2_+_234621551 4.08 ENST00000608381.1
ENST00000373414.3
UGT1A1
UGT1A5
UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5
chr7_+_77469439 4.08 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
PHTF2
putative homeodomain transcription factor 2
chr11_+_44117260 4.05 ENST00000358681.4
EXT2
exostosin glycosyltransferase 2
chr11_+_12766583 4.05 ENST00000361985.2
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr16_+_103816 3.95 ENST00000383018.3
ENST00000417493.1
SNRNP25
small nuclear ribonucleoprotein 25kDa (U11/U12)
chr4_+_37962018 3.95 ENST00000504686.1
PTTG2
pituitary tumor-transforming 2
chr2_+_44001172 3.93 ENST00000260605.8
ENST00000406852.3
ENST00000443170.3
ENST00000398823.2
ENST00000605786.1
DYNC2LI1
dynein, cytoplasmic 2, light intermediate chain 1
chr10_-_51130715 3.90 ENST00000402038.3
PARG
poly (ADP-ribose) glycohydrolase
chr15_+_79166065 3.88 ENST00000559690.1
ENST00000559158.1
MORF4L1
mortality factor 4 like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of BARX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 17.3 GO:2000521 negative regulation of immunological synapse formation(GO:2000521)
5.1 15.4 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
5.1 5.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
4.2 12.6 GO:0031938 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
4.1 12.3 GO:0006597 spermine biosynthetic process(GO:0006597)
3.4 10.3 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
3.3 16.6 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
3.2 16.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
3.1 9.3 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
2.9 17.2 GO:0051661 maintenance of centrosome location(GO:0051661)
2.8 13.9 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
2.7 2.7 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
2.6 25.6 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
2.5 12.6 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
2.5 12.4 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
2.5 4.9 GO:0045454 cell redox homeostasis(GO:0045454)
2.4 14.6 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
2.4 7.2 GO:0002188 translation reinitiation(GO:0002188)
2.2 8.8 GO:0006203 dGTP catabolic process(GO:0006203)
2.1 6.3 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
2.1 10.5 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
1.9 5.7 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
1.9 5.6 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
1.8 22.1 GO:0001778 plasma membrane repair(GO:0001778)
1.8 5.4 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
1.8 7.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
1.7 10.5 GO:0042866 pyruvate biosynthetic process(GO:0042866)
1.7 6.7 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
1.6 14.1 GO:0001887 selenium compound metabolic process(GO:0001887)
1.5 9.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
1.5 12.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
1.5 8.9 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
1.4 4.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
1.4 12.5 GO:0038007 netrin-activated signaling pathway(GO:0038007)
1.3 2.7 GO:0006788 heme oxidation(GO:0006788)
1.3 9.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
1.3 11.6 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
1.2 7.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
1.2 9.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
1.2 3.5 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
1.2 4.7 GO:0030242 pexophagy(GO:0030242)
1.2 10.4 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
1.1 14.9 GO:0070986 left/right axis specification(GO:0070986)
1.1 4.5 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
1.1 4.5 GO:0009106 lipoate metabolic process(GO:0009106)
1.1 3.4 GO:0051257 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
1.1 9.5 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
1.0 8.4 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
1.0 2.9 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
1.0 8.7 GO:0070836 caveola assembly(GO:0070836)
1.0 25.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.9 7.6 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.9 5.6 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.9 13.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.9 4.5 GO:0006041 glucosamine metabolic process(GO:0006041)
0.9 2.7 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.9 19.6 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.8 12.6 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.8 9.2 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.8 6.7 GO:0008090 retrograde axonal transport(GO:0008090)
0.8 42.2 GO:0043486 histone exchange(GO:0043486)
0.8 4.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.8 5.6 GO:0009249 protein lipoylation(GO:0009249)
0.8 4.7 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.8 2.3 GO:1901143 insulin catabolic process(GO:1901143)
0.8 9.3 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.8 5.4 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.8 2.3 GO:1901253 regulation of intracellular transport of viral material(GO:1901252) negative regulation of intracellular transport of viral material(GO:1901253)
0.7 2.9 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.7 3.6 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.7 31.0 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.7 6.3 GO:0072592 oxygen metabolic process(GO:0072592)
0.7 2.8 GO:0035616 maintenance of DNA methylation(GO:0010216) histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.7 7.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.7 2.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.7 4.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.7 8.9 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.7 19.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.7 2.0 GO:0060613 fat pad development(GO:0060613)
0.6 30.2 GO:2000816 negative regulation of mitotic sister chromatid separation(GO:2000816)
0.6 1.8 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.6 4.8 GO:2001140 regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.6 1.1 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.6 8.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.6 5.6 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.6 8.3 GO:0072540 natural killer cell proliferation(GO:0001787) T-helper 17 cell lineage commitment(GO:0072540)
0.5 10.3 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.5 11.9 GO:0003334 keratinocyte development(GO:0003334)
0.5 4.8 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.5 2.5 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.5 5.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.5 2.5 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.5 2.5 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.5 2.5 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.5 3.9 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.5 1.4 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.5 2.4 GO:0046952 ketone body catabolic process(GO:0046952)
0.5 1.4 GO:1904154 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.5 8.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.5 2.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.5 2.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.4 23.7 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.4 4.7 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.4 1.7 GO:0072719 cellular response to cisplatin(GO:0072719)
0.4 5.4 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.4 6.6 GO:0000338 protein deneddylation(GO:0000338)
0.4 3.7 GO:0071763 nuclear membrane organization(GO:0071763)
0.4 18.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.4 10.8 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.4 7.2 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.4 2.4 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.4 1.5 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.4 6.5 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.4 3.4 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.4 1.4 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.3 2.4 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.3 9.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.3 25.4 GO:0010507 negative regulation of autophagy(GO:0010507)
0.3 2.3 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.3 16.4 GO:0036297 interstrand cross-link repair(GO:0036297)
0.3 2.6 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.3 4.8 GO:0033623 regulation of integrin activation(GO:0033623)
0.3 3.7 GO:0031268 pseudopodium organization(GO:0031268)
0.3 2.2 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.3 1.5 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.3 0.9 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.3 4.2 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.3 3.3 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.3 2.3 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.3 26.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.3 16.3 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.3 7.0 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.3 1.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.3 4.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 0.7 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.2 3.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.2 1.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.2 11.8 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.2 5.7 GO:0060134 prepulse inhibition(GO:0060134)
0.2 1.9 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.2 0.7 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.2 4.7 GO:0044849 estrous cycle(GO:0044849)
0.2 3.1 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.2 0.7 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.2 4.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 2.0 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.2 4.0 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.2 6.3 GO:0008045 motor neuron axon guidance(GO:0008045)
0.2 9.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.2 0.9 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.2 0.9 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2 1.4 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.2 0.5 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.2 1.0 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.2 5.1 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.2 1.1 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.2 1.9 GO:1900016 negative regulation of fibroblast migration(GO:0010764) negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.2 0.6 GO:0051135 NK T cell activation(GO:0051132) regulation of NK T cell activation(GO:0051133) positive regulation of NK T cell activation(GO:0051135)
0.1 8.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 5.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 5.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 4.4 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.1 0.7 GO:0021936 regulation of cerebellar granule cell precursor proliferation(GO:0021936) positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.1 1.6 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.1 1.8 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.0 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1 2.4 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 5.3 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.1 4.0 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.1 2.0 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.1 0.6 GO:0050957 equilibrioception(GO:0050957)
0.1 3.0 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.1 5.3 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 6.6 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 0.2 GO:1990523 bone regeneration(GO:1990523)
0.1 2.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 1.8 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 14.5 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 2.0 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 5.5 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 1.5 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 6.2 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 1.6 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 5.3 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.1 10.5 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 1.2 GO:0019321 pentose metabolic process(GO:0019321) neuron cellular homeostasis(GO:0070050)
0.1 1.7 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 0.7 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.1 1.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 11.3 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.1 10.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.6 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 6.7 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.1 1.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.5 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 2.8 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.3 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
0.1 2.4 GO:0097435 fibril organization(GO:0097435)
0.1 0.9 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.1 1.3 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 1.0 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 4.5 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 4.5 GO:0045727 positive regulation of translation(GO:0045727)
0.1 2.2 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 4.7 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 6.4 GO:0002576 platelet degranulation(GO:0002576)
0.0 3.8 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 2.9 GO:0070125 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.0 3.8 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 4.4 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.3 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.6 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.6 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.2 GO:0071428 ribosomal subunit export from nucleus(GO:0000054) ribosomal large subunit export from nucleus(GO:0000055) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0 1.4 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 1.6 GO:0000165 MAPK cascade(GO:0000165)
0.0 1.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 1.3 GO:0043067 regulation of apoptotic process(GO:0042981) regulation of programmed cell death(GO:0043067)
0.0 1.4 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.1 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.3 GO:0042737 drug catabolic process(GO:0042737)
0.0 0.4 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.8 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 1.9 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.0 2.6 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.1 GO:1902172 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.0 0.3 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.5 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 2.5 GO:0006457 protein folding(GO:0006457)
0.0 0.5 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.5 GO:0007162 negative regulation of cell adhesion(GO:0007162)
0.0 1.5 GO:0007586 digestion(GO:0007586)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 12.6 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
3.1 12.6 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
2.9 14.6 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
2.6 20.5 GO:0005672 transcription factor TFIIA complex(GO:0005672)
2.5 17.5 GO:0036449 microtubule minus-end(GO:0036449)
2.2 15.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
1.9 15.4 GO:0032133 chromosome passenger complex(GO:0032133)
1.8 37.3 GO:0000812 Swr1 complex(GO:0000812)
1.7 7.0 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
1.7 10.5 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
1.7 12.0 GO:0000172 ribonuclease MRP complex(GO:0000172)
1.7 6.7 GO:0031673 H zone(GO:0031673)
1.6 4.7 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
1.5 4.5 GO:0044305 calyx of Held(GO:0044305)
1.5 4.4 GO:0043159 acrosomal matrix(GO:0043159)
1.4 4.2 GO:0034455 t-UTP complex(GO:0034455)
1.2 12.2 GO:0000796 condensin complex(GO:0000796)
1.1 3.4 GO:0005715 late recombination nodule(GO:0005715)
1.1 23.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
1.0 7.1 GO:0030870 Mre11 complex(GO:0030870)
0.9 2.7 GO:1902636 kinociliary basal body(GO:1902636)
0.9 5.4 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.8 4.0 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.8 25.1 GO:0005838 proteasome regulatory particle(GO:0005838)
0.7 3.7 GO:0035061 perichromatin fibrils(GO:0005726) interchromatin granule(GO:0035061)
0.7 11.1 GO:0030478 actin cap(GO:0030478)
0.7 12.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.7 2.9 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.7 2.7 GO:0035579 specific granule membrane(GO:0035579)
0.6 5.7 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.6 8.9 GO:0008091 spectrin(GO:0008091)
0.6 4.9 GO:0005610 laminin-5 complex(GO:0005610)
0.6 2.4 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.6 2.3 GO:0033186 CAF-1 complex(GO:0033186)
0.5 10.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.5 2.7 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.5 8.5 GO:0005652 nuclear lamina(GO:0005652)
0.5 7.9 GO:0005802 trans-Golgi network(GO:0005802) Golgi subcompartment(GO:0098791)
0.5 4.7 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.5 16.7 GO:0005685 U1 snRNP(GO:0005685)
0.5 5.7 GO:0070765 gamma-secretase complex(GO:0070765)
0.5 7.6 GO:0005869 dynactin complex(GO:0005869)
0.5 2.0 GO:0031417 NatC complex(GO:0031417)
0.5 9.1 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.5 2.4 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.5 2.8 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.5 6.4 GO:0097227 sperm annulus(GO:0097227)
0.4 9.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.4 4.7 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.4 12.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.4 9.5 GO:0005861 troponin complex(GO:0005861)
0.4 1.6 GO:0070876 SOSS complex(GO:0070876)
0.4 2.3 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.4 7.2 GO:0036020 endolysosome membrane(GO:0036020)
0.4 1.9 GO:0035869 ciliary transition zone(GO:0035869)
0.4 2.9 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.4 2.2 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.3 15.6 GO:0045095 keratin filament(GO:0045095)
0.3 8.4 GO:0030686 90S preribosome(GO:0030686)
0.3 9.2 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.3 8.0 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.3 2.5 GO:0070552 BRISC complex(GO:0070552)
0.3 2.5 GO:0042382 paraspeckles(GO:0042382)
0.3 6.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.3 17.3 GO:0001772 immunological synapse(GO:0001772)
0.3 5.3 GO:0032433 filopodium tip(GO:0032433)
0.3 1.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.3 14.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.3 0.8 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.3 13.0 GO:0031430 M band(GO:0031430)
0.3 3.5 GO:0036038 MKS complex(GO:0036038)
0.3 28.8 GO:0005901 caveola(GO:0005901)
0.2 11.9 GO:0002102 podosome(GO:0002102)
0.2 11.8 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.2 30.5 GO:0042641 actomyosin(GO:0042641)
0.2 13.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 3.7 GO:0031143 pseudopodium(GO:0031143)
0.2 4.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 2.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 6.6 GO:0008180 COP9 signalosome(GO:0008180)
0.2 10.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 4.9 GO:0035861 site of double-strand break(GO:0035861)
0.2 2.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 0.6 GO:0002139 stereocilia coupling link(GO:0002139)
0.2 11.1 GO:0005882 intermediate filament(GO:0005882)
0.2 18.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.2 6.7 GO:0016592 mediator complex(GO:0016592)
0.2 10.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 4.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.2 1.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.2 2.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.2 1.9 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 2.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 1.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 6.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 8.2 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.1 2.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.6 GO:0017119 Golgi transport complex(GO:0017119)
0.1 2.9 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 6.0 GO:0016459 myosin complex(GO:0016459)
0.1 1.5 GO:0038201 TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.1 10.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 4.1 GO:0043198 dendritic shaft(GO:0043198)
0.1 31.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 4.8 GO:0005876 spindle microtubule(GO:0005876)
0.1 1.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 7.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 13.7 GO:0001650 fibrillar center(GO:0001650)
0.1 15.6 GO:0043209 myelin sheath(GO:0043209)
0.1 12.0 GO:0005840 ribosome(GO:0005840)
0.1 6.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 3.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 4.6 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)
0.1 1.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 3.6 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 0.3 GO:0036128 CatSper complex(GO:0036128)
0.1 1.0 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.1 3.7 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 5.7 GO:0005643 nuclear pore(GO:0005643)
0.0 1.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.6 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 3.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 2.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 11.9 GO:0005925 focal adhesion(GO:0005925)
0.0 7.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.8 GO:0031901 early endosome membrane(GO:0031901)
0.0 8.9 GO:0005813 centrosome(GO:0005813)
0.0 4.3 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.4 GO:0012505 endomembrane system(GO:0012505)
0.0 0.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.8 GO:0015629 actin cytoskeleton(GO:0015629)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 14.1 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
4.1 12.4 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
3.4 10.3 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
3.1 9.3 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
3.0 12.1 GO:0004743 pyruvate kinase activity(GO:0004743)
2.9 8.8 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) NADH pyrophosphatase activity(GO:0035529) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
2.3 25.7 GO:0033038 bitter taste receptor activity(GO:0033038)
2.2 17.3 GO:0019863 IgE binding(GO:0019863)
2.1 12.6 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
1.9 9.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.8 7.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
1.7 7.0 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
1.7 15.4 GO:0035174 histone serine kinase activity(GO:0035174)
1.6 4.8 GO:0033149 FFAT motif binding(GO:0033149)
1.6 9.3 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
1.5 10.5 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
1.5 32.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
1.5 10.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
1.3 6.7 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
1.3 7.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
1.2 16.0 GO:0008641 small protein activating enzyme activity(GO:0008641)
1.1 3.4 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
1.1 5.6 GO:0070404 NADH binding(GO:0070404)
1.1 27.6 GO:0008143 poly(A) binding(GO:0008143)
1.1 6.3 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
1.0 2.9 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.9 2.7 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.9 8.9 GO:0042731 PH domain binding(GO:0042731)
0.9 9.7 GO:0004896 cytokine receptor activity(GO:0004896)
0.9 3.5 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.8 8.4 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.8 8.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.8 3.3 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.8 2.4 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.8 19.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.8 12.6 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.8 10.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.8 2.3 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.8 14.6 GO:0035173 histone kinase activity(GO:0035173)
0.8 16.7 GO:0000339 RNA cap binding(GO:0000339)
0.8 12.0 GO:0004526 ribonuclease P activity(GO:0004526)
0.7 12.5 GO:0008432 JUN kinase binding(GO:0008432)
0.7 20.6 GO:0005523 tropomyosin binding(GO:0005523)
0.7 7.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.7 2.9 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.7 36.1 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.7 4.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.6 18.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.6 8.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.6 12.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.6 2.9 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.6 5.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.6 5.3 GO:0008158 hedgehog receptor activity(GO:0008158)
0.6 23.3 GO:0017025 TBP-class protein binding(GO:0017025)
0.6 4.5 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.6 1.7 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.5 5.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.5 5.5 GO:0008494 translation activator activity(GO:0008494)
0.5 2.3 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.4 17.1 GO:0005215 transporter activity(GO:0005215)
0.4 1.3 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.4 3.4 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.4 4.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.4 19.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.4 11.2 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.4 9.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.4 11.8 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.4 10.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.4 8.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.4 2.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.3 22.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.3 1.7 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.3 7.2 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.3 8.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.3 6.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.3 7.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.3 1.8 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.3 2.3 GO:0043559 insulin binding(GO:0043559)
0.3 4.0 GO:0005132 type I interferon receptor binding(GO:0005132)
0.3 8.9 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.3 1.4 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.3 4.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.3 1.0 GO:0008422 beta-glucosidase activity(GO:0008422)
0.3 4.8 GO:0031005 filamin binding(GO:0031005)
0.3 4.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 6.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 0.7 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.2 0.9 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 16.6 GO:0050681 androgen receptor binding(GO:0050681)
0.2 0.7 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.2 2.8 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2 4.0 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.2 1.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.2 3.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 3.2 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.2 4.3 GO:0030515 snoRNA binding(GO:0030515)
0.2 5.3 GO:0070840 dynein complex binding(GO:0070840)
0.2 3.6 GO:0031369 translation initiation factor binding(GO:0031369)
0.2 2.2 GO:0004312 fatty acid synthase activity(GO:0004312)
0.2 17.2 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.2 14.5 GO:0097110 scaffold protein binding(GO:0097110)
0.2 0.6 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 9.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.2 1.8 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.2 13.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2 1.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2 5.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 7.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 0.8 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.2 4.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 2.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 0.5 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.2 2.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 2.4 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 5.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 1.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 1.5 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.9 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 20.3 GO:0005178 integrin binding(GO:0005178)
0.1 2.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.9 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 21.0 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 4.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 4.7 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.1 1.0 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 2.4 GO:0031489 myosin V binding(GO:0031489)
0.1 0.7 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 19.8 GO:0005516 calmodulin binding(GO:0005516)
0.1 9.8 GO:0047485 protein N-terminus binding(GO:0047485)
0.1 1.5 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 31.6 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 15.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 6.7 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.1 2.4 GO:0000049 tRNA binding(GO:0000049)
0.1 3.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 3.9 GO:0017124 SH3 domain binding(GO:0017124)
0.1 9.8 GO:0008083 growth factor activity(GO:0008083)
0.0 0.8 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 1.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.3 GO:0031433 telethonin binding(GO:0031433)
0.0 3.7 GO:0002020 protease binding(GO:0002020)
0.0 10.8 GO:0005543 phospholipid binding(GO:0005543)
0.0 10.2 GO:0003924 GTPase activity(GO:0003924)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 1.1 GO:0008009 chemokine activity(GO:0008009)
0.0 3.2 GO:0000149 SNARE binding(GO:0000149)
0.0 1.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.9 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 1.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 2.3 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 5.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.7 GO:0004386 helicase activity(GO:0004386)
0.0 1.2 GO:0005319 lipid transporter activity(GO:0005319)
0.0 3.8 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.6 GO:0019956 chemokine binding(GO:0019956)
0.0 1.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 5.7 GO:0045296 cadherin binding(GO:0045296)
0.0 0.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.5 GO:0015459 potassium channel regulator activity(GO:0015459)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 14.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.6 33.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.5 34.2 PID AURORA B PATHWAY Aurora B signaling
0.4 5.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.4 12.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.3 12.5 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.3 12.6 PID RAS PATHWAY Regulation of Ras family activation
0.2 22.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.2 5.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.2 23.6 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.2 6.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 4.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 4.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 2.9 PID IL23 PATHWAY IL23-mediated signaling events
0.2 7.9 ST G ALPHA I PATHWAY G alpha i Pathway
0.2 7.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 4.9 PID ATM PATHWAY ATM pathway
0.2 11.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 5.2 PID MYC PATHWAY C-MYC pathway
0.1 7.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 2.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 7.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 5.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 5.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 5.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 12.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 4.2 PID FAS PATHWAY FAS (CD95) signaling pathway
0.1 2.5 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 4.5 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 3.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 5.5 PID CDC42 PATHWAY CDC42 signaling events
0.1 1.5 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 1.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 2.8 PID FOXO PATHWAY FoxO family signaling
0.1 0.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 6.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 1.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 0.7 PID IL5 PATHWAY IL5-mediated signaling events
0.1 7.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 2.6 PID FGF PATHWAY FGF signaling pathway
0.1 0.8 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 2.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 2.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 2.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.4 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.9 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.8 PID E2F PATHWAY E2F transcription factor network
0.0 1.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 17.0 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
1.0 14.6 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
1.0 15.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.7 10.5 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.7 15.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.6 17.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.6 62.0 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.6 12.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.5 8.4 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.5 10.4 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.5 4.7 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.5 15.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.4 13.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.4 14.1 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.4 12.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.4 7.1 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.3 8.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.3 20.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.3 29.2 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.3 9.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.3 7.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.3 20.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 5.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.3 9.3 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.3 10.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.3 4.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.3 8.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.3 6.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 18.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 2.7 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.2 11.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 22.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.2 7.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 3.0 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 15.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.2 3.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.2 5.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 15.0 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.1 4.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 5.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 2.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.6 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.1 1.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 5.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 1.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 2.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 4.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 2.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.0 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 6.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 2.9 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.0 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 1.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 0.8 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 1.5 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 8.1 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 0.7 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 1.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.5 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 6.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.0 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 1.8 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 3.8 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates