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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for CAGUCCA

Z-value: 0.02

Motif logo

logo of

miRNA associated with seed CAGUCCA

NamemiRBASE accession
hsa-miR-455-3p.1
MIMAT0004784

Activity profile of CAGUCCA motif

Sorted Z-values of CAGUCCA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_20812690 3.09 ENST00000375078.3
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr9_-_14314066 2.07 ENST00000397575.3
NFIB
nuclear factor I/B
chr1_-_41131326 1.45 ENST00000372684.3
RIMS3
regulating synaptic membrane exocytosis 3
chr11_-_134281812 1.30 ENST00000392580.1
ENST00000312527.4
B3GAT1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr9_+_103204553 1.20 ENST00000502978.1
ENST00000334943.6
MSANTD3-TMEFF1
TMEFF1
MSANTD3-TMEFF1 readthrough
transmembrane protein with EGF-like and two follistatin-like domains 1
chr19_+_48281842 1.12 ENST00000509570.2
SEPW1
selenoprotein W, 1
chr20_-_32262165 0.98 ENST00000606690.1
ENST00000246190.6
ENST00000439478.1
ENST00000375238.4
NECAB3
N-terminal EF-hand calcium binding protein 3
chr9_-_101471479 0.97 ENST00000259455.2
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr1_+_155290677 0.95 ENST00000368354.3
ENST00000368352.5
RUSC1
RUN and SH3 domain containing 1
chr1_+_201979645 0.93 ENST00000367284.5
ENST00000367283.3
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr14_+_23775971 0.92 ENST00000250405.5
BCL2L2
BCL2-like 2
chr15_+_49170083 0.90 ENST00000530028.2
EID1
EP300 interacting inhibitor of differentiation 1
chr17_-_73851285 0.88 ENST00000589642.1
ENST00000593002.1
ENST00000590221.1
ENST00000344296.4
ENST00000587374.1
ENST00000585462.1
ENST00000433525.2
ENST00000254806.3
WBP2
WW domain binding protein 2
chr2_-_55237484 0.86 ENST00000394609.2
RTN4
reticulon 4
chr9_+_126773880 0.80 ENST00000373615.4
LHX2
LIM homeobox 2
chrX_-_110038990 0.80 ENST00000372045.1
ENST00000394797.4
CHRDL1
chordin-like 1
chr7_+_69064300 0.70 ENST00000342771.4
AUTS2
autism susceptibility candidate 2
chr11_-_129062093 0.70 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr9_+_103235365 0.68 ENST00000374879.4
TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr20_-_48532019 0.66 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr2_-_131850951 0.61 ENST00000409185.1
ENST00000389915.3
FAM168B
family with sequence similarity 168, member B
chr12_+_57943781 0.61 ENST00000455537.2
ENST00000286452.5
KIF5A
kinesin family member 5A
chr2_-_50574856 0.60 ENST00000342183.5
NRXN1
neurexin 1
chr13_+_88324870 0.59 ENST00000325089.6
SLITRK5
SLIT and NTRK-like family, member 5
chr4_+_124320665 0.57 ENST00000394339.2
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr15_+_45315302 0.57 ENST00000267814.9
SORD
sorbitol dehydrogenase
chr17_-_48943706 0.56 ENST00000499247.2
TOB1
transducer of ERBB2, 1
chr17_+_2240775 0.56 ENST00000268989.3
ENST00000426855.2
SGSM2
small G protein signaling modulator 2
chr17_-_8066250 0.55 ENST00000488857.1
ENST00000481878.1
ENST00000316509.6
ENST00000498285.1
VAMP2
RP11-599B13.6
vesicle-associated membrane protein 2 (synaptobrevin 2)
Uncharacterized protein
chr5_+_92919043 0.54 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr12_-_90049828 0.50 ENST00000261173.2
ENST00000348959.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr11_-_31839488 0.50 ENST00000419022.1
ENST00000379132.3
ENST00000379129.2
PAX6
paired box 6
chr11_-_35440796 0.50 ENST00000278379.3
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr7_+_73242069 0.49 ENST00000435050.1
CLDN4
claudin 4
chr3_-_37034702 0.49 ENST00000322716.5
EPM2AIP1
EPM2A (laforin) interacting protein 1
chr1_+_244214577 0.49 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr6_-_159421198 0.48 ENST00000252655.1
ENST00000297262.3
ENST00000367069.2
RSPH3
radial spoke 3 homolog (Chlamydomonas)
chr5_+_67511524 0.47 ENST00000521381.1
ENST00000521657.1
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chrX_+_69664706 0.46 ENST00000194900.4
ENST00000374360.3
DLG3
discs, large homolog 3 (Drosophila)
chr16_-_31147020 0.46 ENST00000568261.1
ENST00000567797.1
ENST00000317508.6
PRSS8
protease, serine, 8
chr15_+_41851211 0.43 ENST00000263798.3
TYRO3
TYRO3 protein tyrosine kinase
chr11_-_118047376 0.42 ENST00000278947.5
SCN2B
sodium channel, voltage-gated, type II, beta subunit
chr14_+_65171099 0.42 ENST00000247226.7
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr3_+_38495333 0.42 ENST00000352511.4
ACVR2B
activin A receptor, type IIB
chr18_-_500692 0.41 ENST00000400256.3
COLEC12
collectin sub-family member 12
chr22_-_38851205 0.41 ENST00000303592.3
KCNJ4
potassium inwardly-rectifying channel, subfamily J, member 4
chr1_-_17304771 0.40 ENST00000375534.3
MFAP2
microfibrillar-associated protein 2
chr3_-_11762202 0.40 ENST00000445411.1
ENST00000404339.1
ENST00000273038.3
VGLL4
vestigial like 4 (Drosophila)
chr17_-_41977964 0.40 ENST00000377184.3
MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr8_+_22224811 0.39 ENST00000381237.1
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr6_+_76458909 0.37 ENST00000369981.3
ENST00000369985.4
MYO6
myosin VI
chrX_+_100474711 0.37 ENST00000402866.1
DRP2
dystrophin related protein 2
chr8_-_30670384 0.36 ENST00000221138.4
ENST00000518243.1
PPP2CB
protein phosphatase 2, catalytic subunit, beta isozyme
chr4_-_71705590 0.35 ENST00000254799.6
GRSF1
G-rich RNA sequence binding factor 1
chr11_-_118966167 0.34 ENST00000530167.1
H2AFX
H2A histone family, member X
chr13_+_25946201 0.34 ENST00000381655.2
ATP8A2
ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr15_+_62853562 0.34 ENST00000561311.1
TLN2
talin 2
chr19_-_43969796 0.32 ENST00000244333.3
LYPD3
LY6/PLAUR domain containing 3
chr19_+_49622646 0.31 ENST00000334186.4
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr15_+_89346657 0.31 ENST00000439576.2
ACAN
aggrecan
chr15_+_96873921 0.31 ENST00000394166.3
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr17_+_45608430 0.31 ENST00000322157.4
NPEPPS
aminopeptidase puromycin sensitive
chr12_+_54447637 0.30 ENST00000609810.1
ENST00000430889.2
HOXC4
HOXC4
homeobox C4
Homeobox protein Hox-C4
chr14_+_58666824 0.29 ENST00000254286.4
ACTR10
actin-related protein 10 homolog (S. cerevisiae)
chr2_+_85360499 0.28 ENST00000282111.3
TCF7L1
transcription factor 7-like 1 (T-cell specific, HMG-box)
chr17_+_38375574 0.27 ENST00000323571.4
ENST00000585043.1
ENST00000394103.3
ENST00000536600.1
WIPF2
WAS/WASL interacting protein family, member 2
chr17_+_27055798 0.27 ENST00000268766.6
NEK8
NIMA-related kinase 8
chr1_-_146644122 0.27 ENST00000254101.3
PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr12_+_57984965 0.26 ENST00000540759.2
ENST00000551772.1
ENST00000550465.1
ENST00000354947.5
PIP4K2C
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr11_-_9286921 0.26 ENST00000328194.3
DENND5A
DENN/MADD domain containing 5A
chr2_-_69870835 0.26 ENST00000409085.4
ENST00000406297.3
AAK1
AP2 associated kinase 1
chr3_-_79068594 0.26 ENST00000436010.2
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr5_-_148930960 0.25 ENST00000261798.5
ENST00000377843.2
CSNK1A1
casein kinase 1, alpha 1
chr12_+_120933904 0.24 ENST00000550178.1
ENST00000550845.1
ENST00000549989.1
ENST00000552870.1
DYNLL1
dynein, light chain, LC8-type 1
chr10_+_88516396 0.24 ENST00000372037.3
BMPR1A
bone morphogenetic protein receptor, type IA
chr19_+_8274204 0.23 ENST00000561053.1
ENST00000251363.5
ENST00000559450.1
ENST00000559336.1
CERS4
ceramide synthase 4
chr3_-_119278446 0.23 ENST00000264246.3
CD80
CD80 molecule
chr12_-_71148413 0.21 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr6_-_29527702 0.21 ENST00000377050.4
UBD
ubiquitin D
chr3_+_183903811 0.21 ENST00000429586.2
ENST00000292808.5
ABCF3
ATP-binding cassette, sub-family F (GCN20), member 3
chr4_-_99851766 0.20 ENST00000450253.2
EIF4E
eukaryotic translation initiation factor 4E
chr1_-_115300592 0.20 ENST00000261443.5
ENST00000534699.1
ENST00000339438.6
ENST00000529046.1
ENST00000525970.1
ENST00000369530.1
ENST00000530886.1
CSDE1
cold shock domain containing E1, RNA-binding
chr17_+_57697216 0.18 ENST00000393043.1
ENST00000269122.3
CLTC
clathrin, heavy chain (Hc)
chr3_-_128902729 0.18 ENST00000451728.2
ENST00000446936.2
ENST00000502976.1
ENST00000500450.2
ENST00000441626.2
CNBP
CCHC-type zinc finger, nucleic acid binding protein
chr19_-_46296011 0.17 ENST00000377735.3
ENST00000270223.6
DMWD
dystrophia myotonica, WD repeat containing
chr6_-_33168391 0.17 ENST00000374685.4
ENST00000413614.2
ENST00000374680.3
RXRB
retinoid X receptor, beta
chr15_+_41952591 0.16 ENST00000566718.1
ENST00000219905.7
ENST00000389936.4
ENST00000545763.1
MGA
MGA, MAX dimerization protein
chr3_+_169684553 0.16 ENST00000337002.4
ENST00000480708.1
SEC62
SEC62 homolog (S. cerevisiae)
chr7_-_14029515 0.16 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ETV1
ets variant 1
chr8_+_22409193 0.16 ENST00000240123.7
SORBS3
sorbin and SH3 domain containing 3
chr5_-_115910630 0.16 ENST00000343348.6
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chrX_+_133507327 0.16 ENST00000332070.3
ENST00000394292.1
ENST00000370799.1
ENST00000416404.2
PHF6
PHD finger protein 6
chr9_+_133710453 0.15 ENST00000318560.5
ABL1
c-abl oncogene 1, non-receptor tyrosine kinase
chr20_+_306221 0.15 ENST00000342665.2
SOX12
SRY (sex determining region Y)-box 12
chr11_-_45307817 0.15 ENST00000020926.3
SYT13
synaptotagmin XIII
chr8_-_93115445 0.15 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr9_+_4679555 0.14 ENST00000381858.1
ENST00000381854.3
CDC37L1
cell division cycle 37-like 1
chr3_-_48700310 0.14 ENST00000164024.4
ENST00000544264.1
CELSR3
cadherin, EGF LAG seven-pass G-type receptor 3
chr6_-_111136513 0.13 ENST00000368911.3
CDK19
cyclin-dependent kinase 19
chr19_+_13049413 0.12 ENST00000316448.5
ENST00000588454.1
CALR
calreticulin
chr3_-_114790179 0.11 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr4_+_184020398 0.11 ENST00000403733.3
ENST00000378925.3
WWC2
WW and C2 domain containing 2
chr6_-_90529418 0.11 ENST00000439638.1
ENST00000369393.3
ENST00000428876.1
MDN1
MDN1, midasin homolog (yeast)
chr1_-_150979333 0.10 ENST00000312210.5
FAM63A
family with sequence similarity 63, member A
chr14_-_53258314 0.10 ENST00000216410.3
ENST00000557604.1
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr19_+_47421933 0.10 ENST00000404338.3
ARHGAP35
Rho GTPase activating protein 35
chr11_+_125439298 0.09 ENST00000278903.6
ENST00000343678.4
ENST00000524723.1
ENST00000527842.2
EI24
etoposide induced 2.4
chr9_+_35749203 0.09 ENST00000456972.2
ENST00000378078.4
RGP1
RGP1 retrograde golgi transport homolog (S. cerevisiae)
chrX_+_48554986 0.08 ENST00000376687.3
ENST00000453214.2
SUV39H1
suppressor of variegation 3-9 homolog 1 (Drosophila)
chr1_-_153950164 0.07 ENST00000271843.4
JTB
jumping translocation breakpoint
chr13_+_42622781 0.06 ENST00000337343.4
ENST00000261491.5
ENST00000379274.2
DGKH
diacylglycerol kinase, eta
chr21_-_36260980 0.06 ENST00000344691.4
ENST00000358356.5
RUNX1
runt-related transcription factor 1
chr9_-_104145795 0.05 ENST00000259407.2
BAAT
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr11_-_47198380 0.04 ENST00000419701.2
ENST00000526342.1
ENST00000528444.1
ENST00000530596.1
ENST00000525398.1
ENST00000319543.6
ENST00000426335.2
ENST00000527927.1
ENST00000525314.1
ARFGAP2
ADP-ribosylation factor GTPase activating protein 2
chr15_-_35047166 0.04 ENST00000290374.4
GJD2
gap junction protein, delta 2, 36kDa
chr6_-_30524951 0.04 ENST00000376621.3
GNL1
guanine nucleotide binding protein-like 1
chr4_-_177713788 0.04 ENST00000280193.2
VEGFC
vascular endothelial growth factor C
chr11_+_64126614 0.03 ENST00000528057.1
ENST00000334205.4
ENST00000294261.4
RPS6KA4
ribosomal protein S6 kinase, 90kDa, polypeptide 4
chr8_-_82395461 0.03 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chr13_-_45915221 0.03 ENST00000309246.5
ENST00000379060.4
ENST00000379055.1
ENST00000527226.1
ENST00000379056.1
TPT1
tumor protein, translationally-controlled 1
chr1_-_16678914 0.03 ENST00000375592.3
FBXO42
F-box protein 42
chr12_+_98987369 0.03 ENST00000401722.3
ENST00000188376.5
ENST00000228318.3
ENST00000551917.1
ENST00000548046.1
ENST00000552981.1
ENST00000551265.1
ENST00000550695.1
ENST00000547534.1
ENST00000549338.1
ENST00000548847.1
SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr5_+_65018017 0.02 ENST00000380985.5
ENST00000502464.1
NLN
neurolysin (metallopeptidase M3 family)
chr8_+_27168988 0.02 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
PTK2B
protein tyrosine kinase 2 beta
chr21_+_47878757 0.02 ENST00000400274.1
ENST00000427143.2
ENST00000318711.7
ENST00000457905.3
ENST00000466639.1
ENST00000435722.3
ENST00000417564.2
DIP2A
DIP2 disco-interacting protein 2 homolog A (Drosophila)
chr20_+_6748311 0.01 ENST00000378827.4
BMP2
bone morphogenetic protein 2
chr11_-_79151695 0.01 ENST00000278550.7
TENM4
teneurin transmembrane protein 4
chr6_-_114292449 0.01 ENST00000519065.1
HDAC2
histone deacetylase 2
chr6_-_10415470 0.01 ENST00000379604.2
ENST00000379613.3
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr8_+_26149007 0.00 ENST00000380737.3
ENST00000524169.1
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chrX_+_153639856 0.00 ENST00000426834.1
ENST00000369790.4
ENST00000454722.1
ENST00000350743.4
ENST00000299328.5
ENST00000351413.4
TAZ
tafazzin
chr17_-_7120525 0.00 ENST00000447163.1
ENST00000399506.2
ENST00000302955.6
DLG4
discs, large homolog 4 (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of CAGUCCA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:2000795 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 0.6 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.2 0.8 GO:0048749 compound eye development(GO:0048749)
0.2 0.6 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.2 0.6 GO:0006059 hexitol metabolic process(GO:0006059)
0.2 0.7 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.9 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 0.9 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.5 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 0.5 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.9 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.3 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.1 0.3 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1 0.2 GO:0048382 mesendoderm development(GO:0048382)
0.1 0.5 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.1 0.3 GO:0009956 radial pattern formation(GO:0009956)
0.1 1.0 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.6 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 0.9 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.4 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.4 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 0.8 GO:0021978 telencephalon regionalization(GO:0021978)
0.1 0.5 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.4 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.1 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.0 0.5 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.2 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.4 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.6 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.0 1.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.2 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.4 GO:0035330 regulation of hippo signaling(GO:0035330)
0.0 0.1 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.0 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.4 GO:0060068 vagina development(GO:0060068)
0.0 0.2 GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0 0.5 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0 0.6 GO:0007625 grooming behavior(GO:0007625)
0.0 0.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.9 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.9 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 1.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.5 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721) positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.1 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 0.1 GO:1900125 regulation of hyaluronan biosynthetic process(GO:1900125)
0.0 0.3 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.9 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 0.2 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.0 GO:0098528 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.5 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.4 GO:0010107 potassium ion import(GO:0010107)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.2 2.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.5 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.6 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 1.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.4 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 5.1 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.5 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.0 GO:0045298 tubulin complex(GO:0045298)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.6 GO:0042734 presynaptic membrane(GO:0042734)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.4 1.3 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.3 1.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.4 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 0.5 GO:0043559 insulin binding(GO:0043559)
0.1 0.4 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 0.4 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.9 GO:0051400 BH domain binding(GO:0051400)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.6 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.4 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 1.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0043236 laminin binding(GO:0043236)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.0 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0070628 proteasome binding(GO:0070628)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.0 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.3 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.6 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.6 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling