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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for DLX1_HOXA3_BARX2

Z-value: 0.59

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Transcription factors associated with DLX1_HOXA3_BARX2

Gene Symbol Gene ID Gene Info
DLX1
ENSG00000144355.10 distal-less homeobox 1
HOXA3
ENSG00000105997.18 homeobox A3
BARX2
ENSG00000043039.5 BARX homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BARX2hg19_v2_chr11_+_129245796_1292458350.236.5e-04Click!

Activity profile of DLX1_HOXA3_BARX2 motif

Sorted Z-values of DLX1_HOXA3_BARX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_117748138 18.05 ENST00000527717.1
FXYD6
FXYD domain containing ion transport regulator 6
chrX_-_13835147 17.57 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr11_-_117747607 15.72 ENST00000540359.1
ENST00000539526.1
FXYD6
FXYD domain containing ion transport regulator 6
chr11_-_117747434 15.35 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD6
FXYD domain containing ion transport regulator 6
chr19_+_50016610 12.67 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr3_+_111718036 11.96 ENST00000455401.2
TAGLN3
transgelin 3
chr3_+_111718173 11.91 ENST00000494932.1
TAGLN3
transgelin 3
chr3_+_111717600 10.64 ENST00000273368.4
TAGLN3
transgelin 3
chr19_+_50016411 10.43 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr3_+_111717511 10.36 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr6_-_32908765 10.31 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr16_-_28634874 9.47 ENST00000395609.1
ENST00000350842.4
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr11_+_121447469 9.03 ENST00000532694.1
ENST00000534286.1
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr3_-_39321512 8.53 ENST00000399220.2
CX3CR1
chemokine (C-X3-C motif) receptor 1
chr16_-_28937027 8.16 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr11_-_128894053 7.81 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr1_-_92952433 7.67 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr6_+_160542870 6.87 ENST00000324965.4
ENST00000457470.2
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr6_-_32908792 6.84 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr4_-_87028478 6.82 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chr12_-_15114603 6.71 ENST00000228945.4
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr2_-_224467093 6.51 ENST00000305409.2
SCG2
secretogranin II
chr19_+_45417921 6.24 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
APOC1
apolipoprotein C-I
chr18_+_32556892 6.16 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr10_-_50970322 6.14 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr2_+_90077680 6.09 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr17_-_73663245 5.50 ENST00000584999.1
ENST00000317905.5
ENST00000420326.2
ENST00000340830.5
RECQL5
RecQ protein-like 5
chr14_+_61654271 5.50 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH
protein kinase C, eta
chr10_-_50970382 5.47 ENST00000419399.1
ENST00000432695.1
OGDHL
oxoglutarate dehydrogenase-like
chr1_+_202317815 5.45 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr21_-_15918618 5.32 ENST00000400564.1
ENST00000400566.1
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr12_-_10282836 5.30 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A
C-type lectin domain family 7, member A
chr6_+_160542821 5.28 ENST00000366963.4
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr7_+_80275953 5.27 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36
CD36 molecule (thrombospondin receptor)
chr4_-_8873531 5.08 ENST00000400677.3
HMX1
H6 family homeobox 1
chr4_-_120243545 4.89 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr5_-_42811986 4.85 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr12_+_7014126 4.82 ENST00000415834.1
ENST00000436789.1
LRRC23
leucine rich repeat containing 23
chr15_-_20193370 4.81 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr5_-_42812143 4.70 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr15_+_84115868 4.58 ENST00000427482.2
SH3GL3
SH3-domain GRB2-like 3
chr11_-_129062093 4.38 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr1_+_207226574 4.23 ENST00000367080.3
ENST00000367079.2
PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr4_-_176733897 4.20 ENST00000393658.2
GPM6A
glycoprotein M6A
chr11_-_111794446 4.19 ENST00000527950.1
CRYAB
crystallin, alpha B
chr12_+_81110684 4.15 ENST00000228644.3
MYF5
myogenic factor 5
chr19_+_18942761 4.14 ENST00000599848.1
UPF1
UPF1 regulator of nonsense transcripts homolog (yeast)
chrX_+_1710484 4.12 ENST00000313871.3
ENST00000381261.3
AKAP17A
A kinase (PRKA) anchor protein 17A
chr4_-_46911223 4.05 ENST00000396533.1
COX7B2
cytochrome c oxidase subunit VIIb2
chr12_+_8276495 4.05 ENST00000546339.1
CLEC4A
C-type lectin domain family 4, member A
chr11_-_64684672 4.00 ENST00000377264.3
ENST00000421419.2
ATG2A
autophagy related 2A
chr1_-_207226313 3.99 ENST00000367084.1
YOD1
YOD1 deubiquitinase
chr4_-_46911248 3.94 ENST00000355591.3
ENST00000505102.1
COX7B2
cytochrome c oxidase subunit VIIb2
chr4_+_80584903 3.89 ENST00000506460.1
RP11-452C8.1
RP11-452C8.1
chr12_-_719573 3.83 ENST00000397265.3
NINJ2
ninjurin 2
chr12_-_10022735 3.79 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr7_-_37026108 3.77 ENST00000396045.3
ELMO1
engulfment and cell motility 1
chr16_-_25122785 3.76 ENST00000563962.1
ENST00000569920.1
RP11-449H11.1
RP11-449H11.1
chr17_-_73663168 3.73 ENST00000578201.1
ENST00000423245.2
RECQL5
RecQ protein-like 5
chr1_+_198608146 3.73 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
PTPRC
protein tyrosine phosphatase, receptor type, C
chr2_+_90273679 3.62 ENST00000423080.2
IGKV3D-7
immunoglobulin kappa variable 3D-7
chr12_+_7014064 3.60 ENST00000443597.2
LRRC23
leucine rich repeat containing 23
chr12_-_22063787 3.60 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr15_+_62853562 3.58 ENST00000561311.1
TLN2
talin 2
chr6_+_26402517 3.56 ENST00000414912.2
BTN3A1
butyrophilin, subfamily 3, member A1
chr6_-_170101749 3.51 ENST00000448612.1
WDR27
WD repeat domain 27
chr12_+_26348246 3.50 ENST00000422622.2
SSPN
sarcospan
chr14_-_107049312 3.50 ENST00000390627.2
IGHV3-53
immunoglobulin heavy variable 3-53
chr5_+_66300446 3.43 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr7_+_150020363 3.42 ENST00000359623.4
ENST00000493307.1
LRRC61
leucine rich repeat containing 61
chr12_+_8276224 3.42 ENST00000229332.5
CLEC4A
C-type lectin domain family 4, member A
chr12_-_16759711 3.38 ENST00000447609.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr1_+_10003486 3.38 ENST00000403197.1
ENST00000377205.1
NMNAT1
nicotinamide nucleotide adenylyltransferase 1
chr3_+_115342349 3.37 ENST00000393780.3
GAP43
growth associated protein 43
chr8_-_66474884 3.37 ENST00000520902.1
CTD-3025N20.2
CTD-3025N20.2
chr14_-_24711865 3.37 ENST00000399423.4
ENST00000267415.7
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr14_-_24711806 3.35 ENST00000540705.1
ENST00000538777.1
ENST00000558566.1
ENST00000559019.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr2_+_90211643 3.35 ENST00000390277.2
IGKV3D-11
immunoglobulin kappa variable 3D-11
chr5_+_36608422 3.29 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr16_-_28621312 3.29 ENST00000314752.7
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr1_+_28199047 3.27 ENST00000373925.1
ENST00000328928.7
ENST00000373927.3
ENST00000427466.1
ENST00000442118.1
ENST00000373921.3
THEMIS2
thymocyte selection associated family member 2
chr2_+_113816215 3.24 ENST00000346807.3
IL36RN
interleukin 36 receptor antagonist
chr1_-_38019878 3.21 ENST00000296215.6
SNIP1
Smad nuclear interacting protein 1
chr17_-_2996290 3.18 ENST00000331459.1
OR1D2
olfactory receptor, family 1, subfamily D, member 2
chr8_-_101571933 3.14 ENST00000520311.1
ANKRD46
ankyrin repeat domain 46
chr7_+_24324726 3.11 ENST00000405982.1
NPY
neuropeptide Y
chr3_+_40518599 3.11 ENST00000314686.5
ENST00000447116.2
ENST00000429348.2
ENST00000456778.1
ZNF619
zinc finger protein 619
chr2_-_86850949 3.11 ENST00000237455.4
RNF103
ring finger protein 103
chr5_-_20575959 3.07 ENST00000507958.1
CDH18
cadherin 18, type 2
chr11_+_89764274 3.06 ENST00000448984.1
ENST00000432771.1
TRIM49C
tripartite motif containing 49C
chr4_+_88896819 3.06 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
SPP1
secreted phosphoprotein 1
chr12_-_48164812 3.05 ENST00000549151.1
ENST00000548919.1
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr8_-_101571964 3.02 ENST00000520552.1
ENST00000521345.1
ENST00000523000.1
ENST00000335659.3
ENST00000358990.3
ENST00000519597.1
ANKRD46
ankyrin repeat domain 46
chr17_+_1674982 3.02 ENST00000572048.1
ENST00000573763.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr12_-_6233828 3.00 ENST00000572068.1
ENST00000261405.5
VWF
von Willebrand factor
chr17_+_67498538 3.00 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr1_+_50575292 2.93 ENST00000371821.1
ENST00000371819.1
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr19_+_18942720 2.93 ENST00000262803.5
UPF1
UPF1 regulator of nonsense transcripts homolog (yeast)
chr6_-_41701581 2.91 ENST00000394283.1
TFEB
transcription factor EB
chr11_-_89541743 2.90 ENST00000329758.1
TRIM49
tripartite motif containing 49
chr18_+_32558208 2.89 ENST00000436190.2
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr7_-_130080818 2.88 ENST00000343969.5
ENST00000541543.1
ENST00000489512.1
CEP41
centrosomal protein 41kDa
chr2_-_201729284 2.86 ENST00000434813.2
CLK1
CDC-like kinase 1
chr20_-_56265680 2.85 ENST00000414037.1
PMEPA1
prostate transmembrane protein, androgen induced 1
chr15_+_58702742 2.83 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chr10_-_115904361 2.81 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chr12_+_7013897 2.77 ENST00000007969.8
ENST00000323702.5
LRRC23
leucine rich repeat containing 23
chrX_-_14047996 2.76 ENST00000380523.4
ENST00000398355.3
GEMIN8
gem (nuclear organelle) associated protein 8
chr3_-_33686743 2.73 ENST00000333778.6
ENST00000539981.1
CLASP2
cytoplasmic linker associated protein 2
chr6_+_89674246 2.67 ENST00000369474.1
AL079342.1
Uncharacterized protein; cDNA FLJ27030 fis, clone SLV07741
chr12_+_8276433 2.63 ENST00000345999.3
ENST00000352620.3
ENST00000360500.3
CLEC4A
C-type lectin domain family 4, member A
chr16_+_31271274 2.62 ENST00000287497.8
ENST00000544665.3
ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
chr11_-_63376013 2.59 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chr2_-_201729393 2.59 ENST00000321356.4
CLK1
CDC-like kinase 1
chr14_-_24711470 2.57 ENST00000559969.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr2_-_90538397 2.56 ENST00000443397.3
RP11-685N3.1
Uncharacterized protein
chr4_-_185275104 2.55 ENST00000317596.3
RP11-290F5.2
RP11-290F5.2
chr10_-_28571015 2.52 ENST00000375719.3
ENST00000375732.1
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr2_+_90248739 2.51 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chr9_-_5339873 2.47 ENST00000223862.1
ENST00000223858.4
RLN1
relaxin 1
chr10_+_18549645 2.47 ENST00000396576.2
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr20_+_3801162 2.46 ENST00000379573.2
ENST00000379567.2
ENST00000455742.1
ENST00000246041.2
AP5S1
adaptor-related protein complex 5, sigma 1 subunit
chr11_+_24518723 2.45 ENST00000336930.6
ENST00000529015.1
ENST00000533227.1
LUZP2
leucine zipper protein 2
chr9_-_100684845 2.44 ENST00000375119.3
C9orf156
chromosome 9 open reading frame 156
chr19_+_42817527 2.42 ENST00000598766.1
TMEM145
transmembrane protein 145
chr2_+_87565634 2.41 ENST00000421835.2
IGKV3OR2-268
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr11_-_13517565 2.40 ENST00000282091.1
ENST00000529816.1
PTH
parathyroid hormone
chr8_-_86253888 2.40 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
CA1
carbonic anhydrase I
chr2_+_79412357 2.36 ENST00000466387.1
CTNNA2
catenin (cadherin-associated protein), alpha 2
chr2_-_89327228 2.32 ENST00000483158.1
IGKV3-11
immunoglobulin kappa variable 3-11
chr18_+_46065393 2.30 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr19_+_9296279 2.29 ENST00000344248.2
OR7D2
olfactory receptor, family 7, subfamily D, member 2
chr11_+_5710919 2.28 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chr2_+_113816685 2.28 ENST00000393200.2
IL36RN
interleukin 36 receptor antagonist
chr1_+_84609944 2.24 ENST00000370685.3
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr8_-_86290333 2.24 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
CA1
carbonic anhydrase I
chr6_+_26402465 2.19 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1
butyrophilin, subfamily 3, member A1
chr5_+_150404904 2.19 ENST00000521632.1
GPX3
glutathione peroxidase 3 (plasma)
chr1_+_101003687 2.17 ENST00000315033.4
GPR88
G protein-coupled receptor 88
chr2_+_68592305 2.15 ENST00000234313.7
PLEK
pleckstrin
chr16_+_33020496 2.12 ENST00000565407.2
IGHV3OR16-8
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr1_-_150738261 2.11 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr11_+_59824060 2.10 ENST00000395032.2
ENST00000358152.2
MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr13_+_31309645 2.08 ENST00000380490.3
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr12_-_15114492 2.03 ENST00000541546.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr11_+_59824127 2.03 ENST00000278865.3
MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr12_-_112123524 2.02 ENST00000327551.6
BRAP
BRCA1 associated protein
chr2_-_89442621 1.99 ENST00000492167.1
IGKV3-20
immunoglobulin kappa variable 3-20
chr18_-_5540471 1.97 ENST00000581833.1
ENST00000544123.1
ENST00000342933.3
ENST00000400111.3
ENST00000585142.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr2_+_191792376 1.96 ENST00000409428.1
ENST00000409215.1
GLS
glutaminase
chr1_+_168148273 1.96 ENST00000367830.3
TIPRL
TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr3_-_194072019 1.94 ENST00000429275.1
ENST00000323830.3
CPN2
carboxypeptidase N, polypeptide 2
chr3_-_151047327 1.93 ENST00000325602.5
P2RY13
purinergic receptor P2Y, G-protein coupled, 13
chr19_-_42746714 1.92 ENST00000222330.3
GSK3A
glycogen synthase kinase 3 alpha
chr14_-_106552755 1.92 ENST00000390600.2
IGHV3-9
immunoglobulin heavy variable 3-9
chr14_-_106926724 1.91 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr16_-_28621298 1.91 ENST00000566189.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr9_-_99540328 1.90 ENST00000223428.4
ENST00000375231.1
ENST00000374641.3
ZNF510
zinc finger protein 510
chr8_-_110986918 1.89 ENST00000297404.1
KCNV1
potassium channel, subfamily V, member 1
chr19_-_19302931 1.89 ENST00000444486.3
ENST00000514819.3
ENST00000585679.1
ENST00000162023.5
MEF2BNB-MEF2B
MEF2BNB
MEF2B
MEF2BNB-MEF2B readthrough
MEF2B neighbor
myocyte enhancer factor 2B
chr14_-_78083112 1.86 ENST00000216484.2
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr3_+_121774202 1.86 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr7_-_150020578 1.85 ENST00000478393.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr7_-_105029812 1.83 ENST00000482897.1
SRPK2
SRSF protein kinase 2
chr6_-_52705641 1.83 ENST00000370989.2
GSTA5
glutathione S-transferase alpha 5
chr17_-_6983550 1.80 ENST00000576617.1
ENST00000416562.2
CLEC10A
C-type lectin domain family 10, member A
chr1_-_211307404 1.78 ENST00000367007.4
KCNH1
potassium voltage-gated channel, subfamily H (eag-related), member 1
chr2_+_196313239 1.76 ENST00000413290.1
AC064834.1
AC064834.1
chr21_+_43619796 1.75 ENST00000398457.2
ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr16_+_48278178 1.74 ENST00000285737.4
ENST00000535754.1
LONP2
lon peptidase 2, peroxisomal
chr3_+_152552685 1.72 ENST00000305097.3
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr1_-_150669604 1.72 ENST00000427665.1
ENST00000540514.1
GOLPH3L
golgi phosphoprotein 3-like
chr5_+_161274685 1.72 ENST00000428797.2
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr15_+_58430567 1.71 ENST00000536493.1
AQP9
aquaporin 9
chr16_-_28608364 1.71 ENST00000533150.1
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr11_+_119076745 1.70 ENST00000264033.4
CBL
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr1_+_50569575 1.68 ENST00000371827.1
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr15_-_55657428 1.68 ENST00000568543.1
CCPG1
cell cycle progression 1
chr9_+_90112767 1.68 ENST00000408954.3
DAPK1
death-associated protein kinase 1
chr19_-_14785622 1.68 ENST00000443157.2
EMR3
egf-like module containing, mucin-like, hormone receptor-like 3
chr2_-_74618964 1.67 ENST00000417090.1
ENST00000409868.1
DCTN1
dynactin 1
chr3_+_195447738 1.67 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
MUC20
mucin 20, cell surface associated
chr3_-_160823158 1.67 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr10_+_96522361 1.65 ENST00000371321.3
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr12_-_8088871 1.63 ENST00000075120.7
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr9_+_90112590 1.63 ENST00000472284.1
DAPK1
death-associated protein kinase 1
chr18_+_32173276 1.62 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA
dystrobrevin, alpha
chr3_-_112127981 1.61 ENST00000486726.2
RP11-231E6.1
RP11-231E6.1
chr5_-_41213607 1.60 ENST00000337836.5
ENST00000433294.1
C6
complement component 6
chr11_+_94706973 1.60 ENST00000536741.1
KDM4D
lysine (K)-specific demethylase 4D
chr4_-_11431188 1.60 ENST00000510712.1
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr19_+_42746927 1.60 ENST00000378108.1
AC006486.1
AC006486.1
chr11_+_71900572 1.60 ENST00000312293.4
FOLR1
folate receptor 1 (adult)
chrX_-_130423200 1.59 ENST00000361420.3
IGSF1
immunoglobulin superfamily, member 1
chr1_-_160549235 1.58 ENST00000368054.3
ENST00000368048.3
ENST00000311224.4
ENST00000368051.3
ENST00000534968.1
CD84
CD84 molecule
chr4_+_56814968 1.58 ENST00000422247.2
CEP135
centrosomal protein 135kDa
chrX_-_138724994 1.56 ENST00000536274.1
MCF2
MCF.2 cell line derived transforming sequence
chr7_+_150020329 1.56 ENST00000323078.7
LRRC61
leucine rich repeat containing 61
chr12_-_23737534 1.54 ENST00000396007.2
SOX5
SRY (sex determining region Y)-box 5
chrX_+_43515467 1.52 ENST00000338702.3
ENST00000542639.1
MAOA
monoamine oxidase A

Network of associatons between targets according to the STRING database.

First level regulatory network of DLX1_HOXA3_BARX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 17.1 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
3.3 23.1 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
3.1 9.2 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
3.0 9.0 GO:1902948 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
2.8 8.5 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
2.6 7.7 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
2.4 7.1 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
2.2 8.7 GO:0071461 cellular response to redox state(GO:0071461)
1.8 17.6 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.7 12.1 GO:0048241 epinephrine transport(GO:0048241)
1.6 6.2 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
1.5 9.3 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
1.3 4.0 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
1.0 3.1 GO:2000861 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
1.0 3.0 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
1.0 3.0 GO:0072709 cellular response to sorbitol(GO:0072709)
0.9 6.8 GO:0007258 JUN phosphorylation(GO:0007258)
0.8 4.2 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.8 5.7 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.8 2.4 GO:1900158 hormone-mediated apoptotic signaling pathway(GO:0008628) positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.8 4.0 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.8 19.1 GO:0006068 ethanol catabolic process(GO:0006068)
0.8 3.0 GO:0030822 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.8 5.3 GO:2000332 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.7 3.7 GO:0048539 immunoglobulin biosynthetic process(GO:0002378) bone marrow development(GO:0048539)
0.7 2.2 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.7 4.2 GO:1903301 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.7 5.5 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.6 1.9 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.6 2.5 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.6 1.9 GO:0042109 negative regulation of tolerance induction(GO:0002644) lymphotoxin A production(GO:0032641) interleukin-4 biosynthetic process(GO:0042097) lymphotoxin A biosynthetic process(GO:0042109) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.6 1.7 GO:0009726 detection of endogenous stimulus(GO:0009726)
0.6 44.4 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.6 1.7 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.6 3.4 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.5 1.6 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.5 2.2 GO:0061743 motor learning(GO:0061743)
0.5 6.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.5 3.1 GO:0032097 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.5 2.6 GO:0015722 canalicular bile acid transport(GO:0015722)
0.5 1.0 GO:0046502 uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.5 2.9 GO:0018095 protein polyglutamylation(GO:0018095)
0.5 1.4 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.5 1.9 GO:1904504 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.4 2.2 GO:0097338 response to clozapine(GO:0097338)
0.4 6.5 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.4 5.6 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.4 0.8 GO:2000366 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.4 2.5 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.4 1.6 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.4 4.1 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.4 3.4 GO:0006531 aspartate metabolic process(GO:0006531)
0.4 2.6 GO:0046485 ether lipid metabolic process(GO:0046485)
0.4 0.7 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.4 1.8 GO:0035063 nuclear speck organization(GO:0035063)
0.4 2.5 GO:0071896 protein localization to adherens junction(GO:0071896)
0.4 2.1 GO:0070560 protein secretion by platelet(GO:0070560)
0.3 5.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.3 2.7 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.3 1.0 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.3 3.4 GO:0016198 axon choice point recognition(GO:0016198)
0.3 1.7 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.3 1.0 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295) negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.3 1.6 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.3 1.6 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.3 1.3 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.3 0.9 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.3 1.8 GO:0006741 NADP biosynthetic process(GO:0006741)
0.3 0.9 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.3 5.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.3 1.5 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.3 6.7 GO:0042832 defense response to protozoan(GO:0042832)
0.3 0.9 GO:0048382 mesendoderm development(GO:0048382)
0.3 0.3 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.3 0.8 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.3 10.2 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.3 4.9 GO:0072643 interferon-gamma secretion(GO:0072643)
0.3 0.8 GO:2000048 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3 1.5 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.3 0.8 GO:0051697 protein delipidation(GO:0051697)
0.3 1.8 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.3 1.3 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.3 1.5 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.2 0.7 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.2 2.9 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.2 2.7 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.2 1.7 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.2 0.7 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.2 2.8 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.2 1.4 GO:0051013 microtubule severing(GO:0051013)
0.2 4.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 0.9 GO:0032218 riboflavin transport(GO:0032218)
0.2 2.1 GO:2001300 lipoxin metabolic process(GO:2001300)
0.2 0.7 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2 1.1 GO:0061107 seminal vesicle development(GO:0061107)
0.2 1.1 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.2 1.7 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.2 0.6 GO:0001694 histamine biosynthetic process(GO:0001694)
0.2 0.8 GO:0048762 mesenchymal cell development(GO:0014031) mesenchymal cell differentiation(GO:0048762)
0.2 0.6 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.2 4.0 GO:0044804 nucleophagy(GO:0044804)
0.2 1.2 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.2 0.8 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.2 0.6 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.2 28.2 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 0.4 GO:0046110 xanthine metabolic process(GO:0046110)
0.2 2.6 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.2 0.7 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.2 2.4 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.2 0.5 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.2 0.9 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.2 1.0 GO:0046487 proline catabolic process to glutamate(GO:0010133) glyoxylate metabolic process(GO:0046487)
0.2 1.0 GO:0001878 response to yeast(GO:0001878)
0.2 0.7 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.2 1.5 GO:0042420 dopamine catabolic process(GO:0042420)
0.2 1.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.2 5.1 GO:0002820 negative regulation of adaptive immune response(GO:0002820)
0.2 0.8 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.1 3.0 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 1.5 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.1 0.4 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 1.3 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 2.4 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.1 1.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 1.1 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 0.3 GO:0002329 pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.1 0.3 GO:0019474 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.1 3.8 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.4 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.1 5.6 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 0.4 GO:0090611 mitotic cytokinesis checkpoint(GO:0044878) ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 4.4 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 0.7 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.6 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 1.1 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 1.7 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.1 0.3 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.1 0.8 GO:1902947 regulation of tau-protein kinase activity(GO:1902947)
0.1 2.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 1.0 GO:0006552 leucine catabolic process(GO:0006552)
0.1 1.4 GO:0090220 meiotic telomere clustering(GO:0045141) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.1 0.8 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 2.8 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 0.4 GO:1901529 positive regulation of anion channel activity(GO:1901529) positive regulation of anion transmembrane transport(GO:1903961)
0.1 0.3 GO:0072098 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) pattern specification involved in mesonephros development(GO:0061227) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.7 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 3.8 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 2.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 0.7 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.1 0.8 GO:0070475 rRNA base methylation(GO:0070475)
0.1 1.7 GO:0071420 cellular response to histamine(GO:0071420)
0.1 5.0 GO:0015701 bicarbonate transport(GO:0015701)
0.1 3.6 GO:0010107 potassium ion import(GO:0010107)
0.1 2.0 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 2.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 1.8 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 2.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.8 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 1.1 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 1.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 1.2 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.1 15.1 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.1 0.3 GO:1904383 response to sodium phosphate(GO:1904383) response to insulin-like growth factor stimulus(GO:1990418)
0.1 0.2 GO:1902573 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.1 0.5 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.9 GO:0006600 creatine metabolic process(GO:0006600)
0.1 9.9 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.1 1.2 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.1 0.9 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.7 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 1.3 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 3.2 GO:0050776 regulation of immune response(GO:0050776)
0.1 0.4 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.3 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.1 1.5 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 0.3 GO:0050955 thermoception(GO:0050955)
0.1 1.0 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.6 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 2.9 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 0.8 GO:0001787 natural killer cell proliferation(GO:0001787)
0.1 8.3 GO:0002377 immunoglobulin production(GO:0002377)
0.1 0.9 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 3.2 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 1.8 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 0.4 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.2 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 0.5 GO:0009249 protein lipoylation(GO:0009249)
0.1 1.3 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 1.1 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 1.1 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.0 1.1 GO:0045087 innate immune response(GO:0045087)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 2.3 GO:0070206 protein trimerization(GO:0070206)
0.0 1.0 GO:0007601 visual perception(GO:0007601) sensory perception of light stimulus(GO:0050953)
0.0 1.2 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.0 2.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 1.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.2 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 1.0 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 1.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 0.9 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 1.5 GO:0035036 sperm-egg recognition(GO:0035036)
0.0 0.9 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 1.4 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.2 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.3 GO:0046541 saliva secretion(GO:0046541)
0.0 1.3 GO:0019835 cytolysis(GO:0019835)
0.0 3.9 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.7 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 1.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.6 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.0 0.3 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 1.5 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.6 GO:0015813 L-glutamate transport(GO:0015813)
0.0 1.8 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.0 1.3 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 1.0 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 9.5 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.8 GO:0030449 regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 5.8 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.4 GO:0030220 platelet formation(GO:0030220)
0.0 0.2 GO:0006706 steroid catabolic process(GO:0006706)
0.0 0.4 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 3.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.3 GO:0009408 response to heat(GO:0009408)
0.0 0.2 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 2.2 GO:0042113 B cell activation(GO:0042113)
0.0 2.5 GO:0016197 endosomal transport(GO:0016197)
0.0 0.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.4 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.2 GO:0032196 transposition(GO:0032196)
0.0 0.0 GO:1901994 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.8 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.6 GO:0002456 T cell mediated immunity(GO:0002456)
0.0 2.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 2.4 GO:0007565 female pregnancy(GO:0007565)
0.0 0.6 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 6.0 GO:0006897 endocytosis(GO:0006897)
0.0 0.5 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.2 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.6 GO:0016079 synaptic vesicle exocytosis(GO:0016079)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 9.3 GO:0010370 perinucleolar chromocenter(GO:0010370)
1.7 11.6 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
1.4 7.1 GO:0044530 supraspliceosomal complex(GO:0044530)
1.2 3.6 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.8 17.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.7 2.0 GO:0071745 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.6 9.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.5 2.6 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.5 3.4 GO:0032584 growth cone membrane(GO:0032584)
0.5 8.0 GO:0045277 respiratory chain complex IV(GO:0045277)
0.5 1.9 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.4 1.1 GO:0036030 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.4 11.4 GO:0035371 microtubule plus-end(GO:0035371)
0.3 6.5 GO:0031045 dense core granule(GO:0031045)
0.3 2.7 GO:0045180 basal cortex(GO:0045180)
0.3 3.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 2.1 GO:0036021 endolysosome lumen(GO:0036021)
0.3 8.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.3 4.2 GO:0097512 cardiac myofibril(GO:0097512)
0.3 3.0 GO:0043203 axon hillock(GO:0043203)
0.3 1.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.3 3.0 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 5.4 GO:0042627 chylomicron(GO:0042627)
0.2 2.0 GO:0033270 paranode region of axon(GO:0033270)
0.2 10.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.2 4.2 GO:0044295 axonal growth cone(GO:0044295)
0.2 2.5 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 3.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.2 4.0 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 2.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 1.6 GO:0070652 HAUS complex(GO:0070652)
0.2 1.6 GO:0005579 membrane attack complex(GO:0005579)
0.2 5.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 40.5 GO:0043209 myelin sheath(GO:0043209)
0.2 1.4 GO:0061574 ASAP complex(GO:0061574)
0.2 5.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2 1.7 GO:0016600 flotillin complex(GO:0016600)
0.2 0.9 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.6 GO:0005899 insulin receptor complex(GO:0005899)
0.1 1.9 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.9 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.6 GO:0036128 CatSper complex(GO:0036128)
0.1 1.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 2.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 2.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.8 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.9 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 0.6 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 0.4 GO:0002177 manchette(GO:0002177)
0.1 1.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 1.7 GO:0097342 ripoptosome(GO:0097342)
0.1 5.7 GO:0031672 A band(GO:0031672)
0.1 1.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 2.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 5.9 GO:0005902 microvillus(GO:0005902)
0.1 1.4 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 1.1 GO:0036038 MKS complex(GO:0036038)
0.1 12.1 GO:0001650 fibrillar center(GO:0001650)
0.1 0.3 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 2.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.4 GO:0090543 Flemming body(GO:0090543)
0.1 17.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 5.8 GO:0005814 centriole(GO:0005814)
0.1 1.7 GO:0042101 T cell receptor complex(GO:0042101)
0.1 6.0 GO:0035579 specific granule membrane(GO:0035579)
0.1 0.9 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.6 GO:0042383 sarcolemma(GO:0042383)
0.0 0.8 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.8 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 3.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 1.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.7 GO:0036019 endolysosome(GO:0036019)
0.0 0.5 GO:0005577 fibrinogen complex(GO:0005577)
0.0 9.8 GO:0045121 membrane raft(GO:0045121)
0.0 2.3 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 1.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 10.6 GO:0005769 early endosome(GO:0005769)
0.0 1.7 GO:0031902 late endosome membrane(GO:0031902)
0.0 4.2 GO:0072562 blood microparticle(GO:0072562)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 39.5 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.0 0.7 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 1.5 GO:0005811 lipid particle(GO:0005811)
0.0 2.8 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.4 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 2.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.0 GO:0001726 ruffle(GO:0001726)
0.0 1.1 GO:0043204 perikaryon(GO:0043204)
0.0 0.6 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 23.1 GO:0005615 extracellular space(GO:0005615)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.7 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.4 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 2.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.4 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 1.3 GO:0099503 secretory granule(GO:0030141) secretory vesicle(GO:0099503)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 23.1 GO:0019770 IgG receptor activity(GO:0019770)
3.0 12.1 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
2.8 8.5 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
2.7 18.6 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
2.3 11.6 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
1.5 9.2 GO:0009378 four-way junction helicase activity(GO:0009378)
1.3 4.0 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
1.1 6.8 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.1 3.4 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
1.1 5.5 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
1.1 5.5 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
1.0 3.0 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.9 5.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.9 8.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.8 43.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.8 6.2 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.8 3.0 GO:0061714 folic acid receptor activity(GO:0061714)
0.7 4.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.7 2.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.6 1.9 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.6 11.7 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.6 1.7 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.6 4.6 GO:0004064 arylesterase activity(GO:0004064)
0.6 17.1 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.5 1.6 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.5 2.6 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.5 1.5 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.5 1.4 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.5 1.4 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.5 3.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.4 1.7 GO:0031685 adenosine receptor binding(GO:0031685)
0.4 1.7 GO:0015254 glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
0.4 1.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.4 2.0 GO:0004359 glutaminase activity(GO:0004359)
0.4 2.5 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.3 1.7 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.3 6.1 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.3 1.0 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.3 3.4 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.3 1.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.3 3.9 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.3 1.0 GO:0032767 copper-dependent protein binding(GO:0032767)
0.3 1.6 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.3 1.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.3 1.8 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.3 1.5 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.3 0.8 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.3 1.4 GO:0034046 poly(G) binding(GO:0034046)
0.3 8.0 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3 0.8 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.3 1.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3 1.1 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.3 2.6 GO:0001851 complement component C3b binding(GO:0001851)
0.3 3.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.3 1.0 GO:0004657