Project
GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
Navigation
Downloads
Results for DPRX
Z-value: 0.30
Motif logo
Transcription factors associated with DPRX
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
DPRX
|
ENSG00000204595.1 | divergent-paired related homeobox |
Activity profile of DPRX motif
Sorted Z-values of DPRX motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr11_-_321340 | 180.70 |
ENST00000526811.1
|
IFITM3
|
interferon induced transmembrane protein 3 |
| chr11_-_321050 | 79.74 |
ENST00000399808.4
|
IFITM3
|
interferon induced transmembrane protein 3 |
| chr11_-_104817919 | 9.27 |
ENST00000533252.1
|
CASP4
|
caspase 4, apoptosis-related cysteine peptidase |
| chr10_-_72362515 | 8.65 |
ENST00000373209.2
ENST00000441259.1 |
PRF1
|
perforin 1 (pore forming protein) |
| chr19_+_2476116 | 7.06 |
ENST00000215631.4
ENST00000587345.1 |
GADD45B
|
growth arrest and DNA-damage-inducible, beta |
| chr2_-_235405168 | 7.00 |
ENST00000339728.3
|
ARL4C
|
ADP-ribosylation factor-like 4C |
| chr7_+_150264365 | 6.95 |
ENST00000255945.2
ENST00000461940.1 |
GIMAP4
|
GTPase, IMAP family member 4 |
| chr5_+_35856951 | 6.71 |
ENST00000303115.3
ENST00000343305.4 ENST00000506850.1 ENST00000511982.1 |
IL7R
|
interleukin 7 receptor |
| chr21_-_28217721 | 6.63 |
ENST00000284984.3
|
ADAMTS1
|
ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| chr1_-_184943610 | 6.46 |
ENST00000367511.3
|
FAM129A
|
family with sequence similarity 129, member A |
| chr16_-_15950868 | 6.14 |
ENST00000396324.3
ENST00000452625.2 ENST00000576790.2 ENST00000300036.5 |
MYH11
|
myosin, heavy chain 11, smooth muscle |
| chr14_+_22931924 | 4.96 |
ENST00000390477.2
|
TRDC
|
T cell receptor delta constant |
| chr14_-_69446034 | 4.94 |
ENST00000193403.6
|
ACTN1
|
actinin, alpha 1 |
| chr7_+_134464414 | 4.70 |
ENST00000361901.2
|
CALD1
|
caldesmon 1 |
| chr12_-_9913489 | 4.67 |
ENST00000228434.3
ENST00000536709.1 |
CD69
|
CD69 molecule |
| chr12_+_58138664 | 4.30 |
ENST00000257910.3
|
TSPAN31
|
tetraspanin 31 |
| chr9_+_116207007 | 4.08 |
ENST00000374140.2
|
RGS3
|
regulator of G-protein signaling 3 |
| chr3_-_18466787 | 4.05 |
ENST00000338745.6
ENST00000450898.1 |
SATB1
|
SATB homeobox 1 |
| chr6_+_31555045 | 3.99 |
ENST00000396101.3
ENST00000490742.1 |
LST1
|
leukocyte specific transcript 1 |
| chr3_-_18466026 | 3.94 |
ENST00000417717.2
|
SATB1
|
SATB homeobox 1 |
| chr11_+_12399071 | 3.90 |
ENST00000539723.1
ENST00000550549.1 |
PARVA
|
parvin, alpha |
| chr2_-_85555385 | 3.88 |
ENST00000377386.3
|
TGOLN2
|
trans-golgi network protein 2 |
| chr2_-_85555355 | 3.85 |
ENST00000282120.2
ENST00000398263.2 |
TGOLN2
|
trans-golgi network protein 2 |
| chr1_-_151965048 | 3.78 |
ENST00000368809.1
|
S100A10
|
S100 calcium binding protein A10 |
| chr1_+_111415757 | 3.55 |
ENST00000429072.2
ENST00000271324.5 |
CD53
|
CD53 molecule |
| chr2_+_120517174 | 3.40 |
ENST00000263708.2
|
PTPN4
|
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
| chr15_-_42565606 | 3.38 |
ENST00000307216.6
ENST00000448392.1 |
TMEM87A
|
transmembrane protein 87A |
| chr12_+_56552128 | 3.37 |
ENST00000548580.1
ENST00000293422.5 ENST00000348108.4 ENST00000549017.1 ENST00000549566.1 ENST00000536128.1 ENST00000547649.1 ENST00000547408.1 ENST00000551589.1 ENST00000549392.1 ENST00000548400.1 ENST00000548293.1 |
MYL6
|
myosin, light chain 6, alkali, smooth muscle and non-muscle |
| chr12_+_58138800 | 3.32 |
ENST00000547992.1
ENST00000552816.1 ENST00000547472.1 |
TSPAN31
|
tetraspanin 31 |
| chr11_-_61560053 | 3.21 |
ENST00000537328.1
|
TMEM258
|
transmembrane protein 258 |
| chr17_+_43318434 | 3.17 |
ENST00000587489.1
|
FMNL1
|
formin-like 1 |
| chr12_+_54718904 | 3.11 |
ENST00000262061.2
ENST00000549043.1 ENST00000552218.1 ENST00000553231.1 ENST00000552362.1 ENST00000455864.2 ENST00000416254.2 ENST00000549116.1 ENST00000551779.1 |
COPZ1
|
coatomer protein complex, subunit zeta 1 |
| chr10_+_51572408 | 3.10 |
ENST00000374082.1
|
NCOA4
|
nuclear receptor coactivator 4 |
| chr1_+_16767167 | 3.07 |
ENST00000337132.5
|
NECAP2
|
NECAP endocytosis associated 2 |
| chr19_+_41284121 | 3.05 |
ENST00000594800.1
ENST00000357052.2 ENST00000602173.1 |
RAB4B
|
RAB4B, member RAS oncogene family |
| chr1_+_81771806 | 3.04 |
ENST00000370721.1
ENST00000370727.1 ENST00000370725.1 ENST00000370723.1 ENST00000370728.1 ENST00000370730.1 |
LPHN2
|
latrophilin 2 |
| chr1_+_16767195 | 2.97 |
ENST00000504551.2
ENST00000457722.2 ENST00000406746.1 ENST00000443980.2 |
NECAP2
|
NECAP endocytosis associated 2 |
| chr12_+_104359641 | 2.89 |
ENST00000537100.1
|
TDG
|
thymine-DNA glycosylase |
| chr20_-_34330129 | 2.89 |
ENST00000397370.3
ENST00000528062.3 ENST00000407261.4 ENST00000374038.3 ENST00000361162.6 |
RBM39
|
RNA binding motif protein 39 |
| chr1_-_22263790 | 2.87 |
ENST00000374695.3
|
HSPG2
|
heparan sulfate proteoglycan 2 |
| chr3_+_10068095 | 2.86 |
ENST00000287647.3
ENST00000383807.1 ENST00000383806.1 ENST00000419585.1 |
FANCD2
|
Fanconi anemia, complementation group D2 |
| chr8_+_1772132 | 2.85 |
ENST00000349830.3
ENST00000520359.1 ENST00000518288.1 ENST00000398560.1 |
ARHGEF10
|
Rho guanine nucleotide exchange factor (GEF) 10 |
| chr14_+_22919081 | 2.83 |
ENST00000390473.1
|
TRDJ1
|
T cell receptor delta joining 1 |
| chr21_-_43346790 | 2.78 |
ENST00000329623.7
|
C2CD2
|
C2 calcium-dependent domain containing 2 |
| chr11_-_61560254 | 2.72 |
ENST00000543510.1
|
TMEM258
|
transmembrane protein 258 |
| chr12_+_104359614 | 2.70 |
ENST00000266775.9
ENST00000544861.1 |
TDG
|
thymine-DNA glycosylase |
| chr2_-_190044480 | 2.69 |
ENST00000374866.3
|
COL5A2
|
collagen, type V, alpha 2 |
| chr7_+_134464376 | 2.65 |
ENST00000454108.1
ENST00000361675.2 |
CALD1
|
caldesmon 1 |
| chr15_+_81475047 | 2.56 |
ENST00000559388.1
|
IL16
|
interleukin 16 |
| chr12_+_124069070 | 2.56 |
ENST00000262225.3
ENST00000438031.2 |
TMED2
|
transmembrane emp24 domain trafficking protein 2 |
| chr11_+_65343494 | 2.51 |
ENST00000309295.4
ENST00000533237.1 |
EHBP1L1
|
EH domain binding protein 1-like 1 |
| chr7_+_134576151 | 2.50 |
ENST00000393118.2
|
CALD1
|
caldesmon 1 |
| chr10_+_51572339 | 2.42 |
ENST00000344348.6
|
NCOA4
|
nuclear receptor coactivator 4 |
| chr16_+_28722809 | 2.41 |
ENST00000566866.1
|
EIF3C
|
eukaryotic translation initiation factor 3, subunit C |
| chr7_-_97881429 | 2.41 |
ENST00000420697.1
ENST00000379795.3 ENST00000415086.1 ENST00000542604.1 ENST00000447648.2 |
TECPR1
|
tectonin beta-propeller repeat containing 1 |
| chr11_+_60681346 | 2.40 |
ENST00000227525.3
|
TMEM109
|
transmembrane protein 109 |
| chr11_-_2323290 | 2.37 |
ENST00000381153.3
|
C11orf21
|
chromosome 11 open reading frame 21 |
| chr10_+_70661014 | 2.34 |
ENST00000373585.3
|
DDX50
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 |
| chr8_-_71520513 | 2.34 |
ENST00000262213.2
ENST00000536748.1 ENST00000518678.1 |
TRAM1
|
translocation associated membrane protein 1 |
| chr9_-_95244781 | 2.32 |
ENST00000375544.3
ENST00000375543.1 ENST00000395538.3 ENST00000450139.2 |
ASPN
|
asporin |
| chr12_+_113344755 | 2.31 |
ENST00000550883.1
|
OAS1
|
2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| chr14_+_91581011 | 2.31 |
ENST00000523894.1
ENST00000522322.1 ENST00000523771.1 |
C14orf159
|
chromosome 14 open reading frame 159 |
| chr11_+_2323349 | 2.30 |
ENST00000381121.3
|
TSPAN32
|
tetraspanin 32 |
| chrX_+_100878079 | 2.28 |
ENST00000471229.2
|
ARMCX3
|
armadillo repeat containing, X-linked 3 |
| chr5_-_180669197 | 2.16 |
ENST00000502905.1
|
GNB2L1
|
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 |
| chr7_-_15726296 | 2.10 |
ENST00000262041.5
|
MEOX2
|
mesenchyme homeobox 2 |
| chr5_-_180669236 | 2.06 |
ENST00000507756.1
|
GNB2L1
|
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 |
| chr7_+_134576317 | 2.05 |
ENST00000424922.1
ENST00000495522.1 |
CALD1
|
caldesmon 1 |
| chr6_+_31554826 | 1.98 |
ENST00000376089.2
ENST00000396112.2 |
LST1
|
leukocyte specific transcript 1 |
| chr16_-_28415162 | 1.98 |
ENST00000398944.3
ENST00000398943.3 ENST00000380876.4 |
EIF3CL
|
eukaryotic translation initiation factor 3, subunit C-like |
| chr22_-_43355858 | 1.94 |
ENST00000402229.1
ENST00000407585.1 ENST00000453079.1 |
PACSIN2
|
protein kinase C and casein kinase substrate in neurons 2 |
| chr16_+_28722684 | 1.92 |
ENST00000331666.6
ENST00000395587.1 ENST00000569690.1 ENST00000564243.1 |
EIF3C
|
eukaryotic translation initiation factor 3, subunit C |
| chr1_-_150780757 | 1.91 |
ENST00000271651.3
|
CTSK
|
cathepsin K |
| chr5_+_139781393 | 1.90 |
ENST00000360839.2
ENST00000297183.6 ENST00000421134.1 ENST00000394723.3 ENST00000511151.1 |
ANKHD1
|
ankyrin repeat and KH domain containing 1 |
| chr12_+_54891495 | 1.90 |
ENST00000293373.6
|
NCKAP1L
|
NCK-associated protein 1-like |
| chr11_-_104905840 | 1.85 |
ENST00000526568.1
ENST00000393136.4 ENST00000531166.1 ENST00000534497.1 ENST00000527979.1 ENST00000446369.1 ENST00000353247.5 ENST00000528974.1 ENST00000533400.1 ENST00000525825.1 ENST00000436863.3 |
CASP1
|
caspase 1, apoptosis-related cysteine peptidase |
| chr14_+_85996471 | 1.84 |
ENST00000330753.4
|
FLRT2
|
fibronectin leucine rich transmembrane protein 2 |
| chr11_-_104972158 | 1.84 |
ENST00000598974.1
ENST00000593315.1 ENST00000594519.1 ENST00000415981.2 ENST00000525374.1 ENST00000375707.1 |
CASP1
CARD16
CARD17
|
caspase 1, apoptosis-related cysteine peptidase caspase recruitment domain family, member 16 caspase recruitment domain family, member 17 |
| chr18_-_52989217 | 1.81 |
ENST00000570287.2
|
TCF4
|
transcription factor 4 |
| chr5_+_78365577 | 1.81 |
ENST00000518666.1
ENST00000521567.1 |
BHMT2
|
betaine--homocysteine S-methyltransferase 2 |
| chr8_-_95274536 | 1.78 |
ENST00000297596.2
ENST00000396194.2 |
GEM
|
GTP binding protein overexpressed in skeletal muscle |
| chrX_-_77150985 | 1.75 |
ENST00000358075.6
|
MAGT1
|
magnesium transporter 1 |
| chr10_+_104178946 | 1.74 |
ENST00000432590.1
|
FBXL15
|
F-box and leucine-rich repeat protein 15 |
| chr17_-_15168624 | 1.74 |
ENST00000312280.3
ENST00000494511.1 ENST00000580584.1 |
PMP22
|
peripheral myelin protein 22 |
| chr17_+_73663402 | 1.70 |
ENST00000355423.3
|
SAP30BP
|
SAP30 binding protein |
| chrX_-_3631635 | 1.68 |
ENST00000262848.5
|
PRKX
|
protein kinase, X-linked |
| chr1_+_202317815 | 1.62 |
ENST00000608999.1
ENST00000336894.4 ENST00000480184.1 |
PPP1R12B
|
protein phosphatase 1, regulatory subunit 12B |
| chr11_+_64948665 | 1.56 |
ENST00000533820.1
|
CAPN1
|
calpain 1, (mu/I) large subunit |
| chr22_+_23161491 | 1.50 |
ENST00000390316.2
|
IGLV3-9
|
immunoglobulin lambda variable 3-9 (gene/pseudogene) |
| chr5_-_150460914 | 1.49 |
ENST00000389378.2
|
TNIP1
|
TNFAIP3 interacting protein 1 |
| chr11_-_61734599 | 1.48 |
ENST00000532601.1
|
FTH1
|
ferritin, heavy polypeptide 1 |
| chr12_+_6949964 | 1.46 |
ENST00000541978.1
ENST00000435982.2 |
GNB3
|
guanine nucleotide binding protein (G protein), beta polypeptide 3 |
| chr3_-_54962100 | 1.44 |
ENST00000273286.5
|
LRTM1
|
leucine-rich repeats and transmembrane domains 1 |
| chr9_+_17134980 | 1.42 |
ENST00000380647.3
|
CNTLN
|
centlein, centrosomal protein |
| chr11_+_2323236 | 1.42 |
ENST00000182290.4
|
TSPAN32
|
tetraspanin 32 |
| chr16_+_81272287 | 1.40 |
ENST00000425577.2
ENST00000564552.1 |
BCMO1
|
beta-carotene 15,15'-monooxygenase 1 |
| chr9_+_17135016 | 1.40 |
ENST00000425824.1
ENST00000262360.5 ENST00000380641.4 |
CNTLN
|
centlein, centrosomal protein |
| chr11_+_64949158 | 1.38 |
ENST00000527739.1
ENST00000526966.1 ENST00000533129.1 ENST00000524773.1 |
CAPN1
|
calpain 1, (mu/I) large subunit |
| chr17_+_41150290 | 1.38 |
ENST00000589037.1
ENST00000253788.5 |
RPL27
|
ribosomal protein L27 |
| chr16_-_67427389 | 1.37 |
ENST00000562206.1
ENST00000290942.5 ENST00000393957.2 |
TPPP3
|
tubulin polymerization-promoting protein family member 3 |
| chr3_+_63953415 | 1.36 |
ENST00000484332.1
|
ATXN7
|
ataxin 7 |
| chr19_+_49999631 | 1.33 |
ENST00000270625.2
ENST00000596873.1 ENST00000594493.1 ENST00000599561.1 |
RPS11
|
ribosomal protein S11 |
| chr5_+_139781445 | 1.28 |
ENST00000532219.1
ENST00000394722.3 |
ANKHD1-EIF4EBP3
ANKHD1
|
ANKHD1-EIF4EBP3 readthrough ankyrin repeat and KH domain containing 1 |
| chr12_-_103310987 | 1.28 |
ENST00000307000.2
|
PAH
|
phenylalanine hydroxylase |
| chr4_+_89299885 | 1.27 |
ENST00000380265.5
ENST00000273960.3 |
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| chr18_-_64271363 | 1.24 |
ENST00000262150.2
|
CDH19
|
cadherin 19, type 2 |
| chr6_-_32908792 | 1.23 |
ENST00000418107.2
|
HLA-DMB
|
major histocompatibility complex, class II, DM beta |
| chrX_-_33229636 | 1.21 |
ENST00000357033.4
|
DMD
|
dystrophin |
| chr1_+_202431859 | 1.20 |
ENST00000391959.3
ENST00000367270.4 |
PPP1R12B
|
protein phosphatase 1, regulatory subunit 12B |
| chr18_-_52989525 | 1.17 |
ENST00000457482.3
|
TCF4
|
transcription factor 4 |
| chr14_+_61995722 | 1.17 |
ENST00000556347.1
|
RP11-47I22.4
|
RP11-47I22.4 |
| chr2_-_26251481 | 1.17 |
ENST00000599234.1
|
AC013449.1
|
Uncharacterized protein |
| chr4_+_153701081 | 1.16 |
ENST00000451320.2
ENST00000429148.2 ENST00000353617.2 ENST00000405727.2 ENST00000356064.3 |
ARFIP1
|
ADP-ribosylation factor interacting protein 1 |
| chr6_-_33290580 | 1.14 |
ENST00000446511.1
ENST00000446403.1 ENST00000414083.2 ENST00000266000.6 ENST00000374542.5 |
DAXX
|
death-domain associated protein |
| chr5_-_77072085 | 1.14 |
ENST00000518338.2
ENST00000520039.1 ENST00000306388.6 ENST00000520361.1 |
TBCA
|
tubulin folding cofactor A |
| chr10_-_103578182 | 1.11 |
ENST00000439817.1
|
MGEA5
|
meningioma expressed antigen 5 (hyaluronidase) |
| chr11_+_64949343 | 1.09 |
ENST00000279247.6
ENST00000532285.1 ENST00000534373.1 |
CAPN1
|
calpain 1, (mu/I) large subunit |
| chr19_-_50529193 | 1.07 |
ENST00000596445.1
ENST00000599538.1 |
VRK3
|
vaccinia related kinase 3 |
| chr14_-_106518922 | 1.04 |
ENST00000390598.2
|
IGHV3-7
|
immunoglobulin heavy variable 3-7 |
| chr19_+_56165480 | 1.02 |
ENST00000450554.2
|
U2AF2
|
U2 small nuclear RNA auxiliary factor 2 |
| chr17_+_77021702 | 0.99 |
ENST00000392445.2
ENST00000354124.3 |
C1QTNF1
|
C1q and tumor necrosis factor related protein 1 |
| chr8_-_120605194 | 0.98 |
ENST00000522167.1
|
ENPP2
|
ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| chr2_-_98280383 | 0.97 |
ENST00000289228.5
|
ACTR1B
|
ARP1 actin-related protein 1 homolog B, centractin beta (yeast) |
| chr1_-_68516393 | 0.95 |
ENST00000395201.1
|
DIRAS3
|
DIRAS family, GTP-binding RAS-like 3 |
| chr9_-_13279563 | 0.94 |
ENST00000541718.1
|
MPDZ
|
multiple PDZ domain protein |
| chr10_-_103578162 | 0.92 |
ENST00000361464.3
ENST00000357797.5 ENST00000370094.3 |
MGEA5
|
meningioma expressed antigen 5 (hyaluronidase) |
| chr5_-_77072145 | 0.92 |
ENST00000380377.4
|
TBCA
|
tubulin folding cofactor A |
| chrX_+_15525426 | 0.91 |
ENST00000342014.6
|
BMX
|
BMX non-receptor tyrosine kinase |
| chr14_-_22005343 | 0.85 |
ENST00000327430.3
|
SALL2
|
spalt-like transcription factor 2 |
| chrX_-_53449593 | 0.78 |
ENST00000375340.6
ENST00000322213.4 |
SMC1A
|
structural maintenance of chromosomes 1A |
| chr4_+_169418255 | 0.77 |
ENST00000505667.1
ENST00000511948.1 |
PALLD
|
palladin, cytoskeletal associated protein |
| chr1_+_43148059 | 0.76 |
ENST00000321358.7
ENST00000332220.6 |
YBX1
|
Y box binding protein 1 |
| chr12_+_122516626 | 0.76 |
ENST00000319080.7
|
MLXIP
|
MLX interacting protein |
| chr12_+_133563026 | 0.76 |
ENST00000540238.1
ENST00000328654.5 ENST00000544181.1 |
ZNF26
|
zinc finger protein 26 |
| chr1_-_27481401 | 0.75 |
ENST00000263980.3
|
SLC9A1
|
solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| chr10_+_97515409 | 0.74 |
ENST00000371207.3
ENST00000543964.1 |
ENTPD1
|
ectonucleoside triphosphate diphosphohydrolase 1 |
| chr4_-_73935409 | 0.73 |
ENST00000507544.2
ENST00000295890.4 |
COX18
|
COX18 cytochrome C oxidase assembly factor |
| chr12_+_104359576 | 0.69 |
ENST00000392872.3
ENST00000436021.2 |
TDG
|
thymine-DNA glycosylase |
| chr8_-_110656995 | 0.67 |
ENST00000276646.9
ENST00000533065.1 |
SYBU
|
syntabulin (syntaxin-interacting) |
| chr7_-_135412925 | 0.64 |
ENST00000354042.4
|
SLC13A4
|
solute carrier family 13 (sodium/sulfate symporter), member 4 |
| chr14_-_22005062 | 0.64 |
ENST00000317492.5
|
SALL2
|
spalt-like transcription factor 2 |
| chr1_+_20396649 | 0.63 |
ENST00000375108.3
|
PLA2G5
|
phospholipase A2, group V |
| chr6_-_35480640 | 0.61 |
ENST00000428978.1
ENST00000322263.4 |
TULP1
|
tubby like protein 1 |
| chrX_+_99899180 | 0.61 |
ENST00000373004.3
|
SRPX2
|
sushi-repeat containing protein, X-linked 2 |
| chr2_+_26915584 | 0.60 |
ENST00000302909.3
|
KCNK3
|
potassium channel, subfamily K, member 3 |
| chr12_-_56106060 | 0.59 |
ENST00000452168.2
|
ITGA7
|
integrin, alpha 7 |
| chr1_+_207262540 | 0.59 |
ENST00000452902.2
|
C4BPB
|
complement component 4 binding protein, beta |
| chr3_+_15468862 | 0.58 |
ENST00000396842.2
|
EAF1
|
ELL associated factor 1 |
| chr1_+_207262881 | 0.54 |
ENST00000451804.2
|
C4BPB
|
complement component 4 binding protein, beta |
| chr6_-_30640811 | 0.51 |
ENST00000376442.3
|
DHX16
|
DEAH (Asp-Glu-Ala-His) box polypeptide 16 |
| chr1_+_120049826 | 0.50 |
ENST00000369413.3
ENST00000235547.6 ENST00000528909.1 |
HSD3B1
|
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
| chr18_+_56530136 | 0.50 |
ENST00000591083.1
|
ZNF532
|
zinc finger protein 532 |
| chr9_-_13279406 | 0.49 |
ENST00000546205.1
|
MPDZ
|
multiple PDZ domain protein |
| chr7_-_99573677 | 0.49 |
ENST00000292401.4
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding |
| chr19_-_14628645 | 0.49 |
ENST00000598235.1
|
DNAJB1
|
DnaJ (Hsp40) homolog, subfamily B, member 1 |
| chr16_-_20556492 | 0.49 |
ENST00000568098.1
|
ACSM2B
|
acyl-CoA synthetase medium-chain family member 2B |
| chr1_+_74701062 | 0.48 |
ENST00000326637.3
|
TNNI3K
|
TNNI3 interacting kinase |
| chr9_+_2015335 | 0.47 |
ENST00000349721.2
ENST00000357248.2 ENST00000450198.1 |
SMARCA2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| chr6_-_22297730 | 0.46 |
ENST00000306482.1
|
PRL
|
prolactin |
| chr1_+_207262170 | 0.45 |
ENST00000367078.3
|
C4BPB
|
complement component 4 binding protein, beta |
| chr14_+_50234309 | 0.40 |
ENST00000298307.5
|
KLHDC2
|
kelch domain containing 2 |
| chr2_+_3622932 | 0.39 |
ENST00000406376.1
|
RPS7
|
ribosomal protein S7 |
| chr1_+_12916941 | 0.36 |
ENST00000240189.2
|
PRAMEF2
|
PRAME family member 2 |
| chr2_+_3622893 | 0.36 |
ENST00000407445.3
ENST00000403564.1 |
RPS7
|
ribosomal protein S7 |
| chr17_-_7080227 | 0.35 |
ENST00000574330.1
|
ASGR1
|
asialoglycoprotein receptor 1 |
| chrX_+_69488174 | 0.33 |
ENST00000480877.2
ENST00000307959.8 |
ARR3
|
arrestin 3, retinal (X-arrestin) |
| chr8_+_48173514 | 0.31 |
ENST00000518074.1
ENST00000541342.1 |
SPIDR
|
scaffolding protein involved in DNA repair |
| chr2_+_113342163 | 0.29 |
ENST00000409719.1
|
CHCHD5
|
coiled-coil-helix-coiled-coil-helix domain containing 5 |
| chr1_-_94586651 | 0.24 |
ENST00000535735.1
ENST00000370225.3 |
ABCA4
|
ATP-binding cassette, sub-family A (ABC1), member 4 |
| chr11_-_62752162 | 0.24 |
ENST00000458333.2
ENST00000421062.2 |
SLC22A6
|
solute carrier family 22 (organic anion transporter), member 6 |
| chr2_-_30144432 | 0.23 |
ENST00000389048.3
|
ALK
|
anaplastic lymphoma receptor tyrosine kinase |
| chr2_+_3622795 | 0.19 |
ENST00000304921.5
|
RPS7
|
ribosomal protein S7 |
| chr12_+_113344582 | 0.19 |
ENST00000202917.5
ENST00000445409.2 ENST00000452357.2 |
OAS1
|
2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| chr11_-_118436606 | 0.19 |
ENST00000530872.1
|
IFT46
|
intraflagellar transport 46 homolog (Chlamydomonas) |
| chr3_+_128779610 | 0.19 |
ENST00000307395.4
|
GP9
|
glycoprotein IX (platelet) |
| chr15_+_34261089 | 0.19 |
ENST00000383263.5
|
CHRM5
|
cholinergic receptor, muscarinic 5 |
| chr1_-_13452656 | 0.17 |
ENST00000376132.3
|
PRAMEF13
|
PRAME family member 13 |
| chr10_+_15085936 | 0.17 |
ENST00000378217.3
|
OLAH
|
oleoyl-ACP hydrolase |
| chr8_-_124037890 | 0.17 |
ENST00000519018.1
ENST00000523036.1 |
DERL1
|
derlin 1 |
| chr2_+_234216454 | 0.15 |
ENST00000447536.1
ENST00000409110.1 |
SAG
|
S-antigen; retina and pineal gland (arrestin) |
| chr11_+_107879459 | 0.15 |
ENST00000393094.2
|
CUL5
|
cullin 5 |
| chr1_+_207262627 | 0.14 |
ENST00000391923.1
|
C4BPB
|
complement component 4 binding protein, beta |
| chr14_-_94789663 | 0.14 |
ENST00000557225.1
ENST00000341584.3 |
SERPINA6
|
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 |
| chr9_-_22009297 | 0.13 |
ENST00000276925.6
|
CDKN2B
|
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) |
| chr18_+_32290218 | 0.11 |
ENST00000348997.5
ENST00000588949.1 ENST00000597599.1 |
DTNA
|
dystrobrevin, alpha |
| chr4_-_122791583 | 0.10 |
ENST00000506636.1
ENST00000264499.4 |
BBS7
|
Bardet-Biedl syndrome 7 |
| chr2_+_128175997 | 0.09 |
ENST00000234071.3
ENST00000429925.1 ENST00000442644.1 ENST00000453608.2 |
PROC
|
protein C (inactivator of coagulation factors Va and VIIIa) |
| chr9_-_22009241 | 0.09 |
ENST00000380142.4
|
CDKN2B
|
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) |
| chr10_+_15085895 | 0.08 |
ENST00000378228.3
|
OLAH
|
oleoyl-ACP hydrolase |
| chr8_+_94752349 | 0.08 |
ENST00000391680.1
|
RBM12B-AS1
|
RBM12B antisense RNA 1 |
| chr2_+_69201705 | 0.05 |
ENST00000377938.2
|
GKN1
|
gastrokine 1 |
| chr17_-_19771242 | 0.05 |
ENST00000361658.2
|
ULK2
|
unc-51 like autophagy activating kinase 2 |
| chr9_-_112083229 | 0.04 |
ENST00000374566.3
ENST00000374557.4 |
EPB41L4B
|
erythrocyte membrane protein band 4.1 like 4B |
| chr19_-_50370799 | 0.04 |
ENST00000600910.1
ENST00000322344.3 ENST00000600573.1 |
PNKP
|
polynucleotide kinase 3'-phosphatase |
| chr7_+_89975979 | 0.03 |
ENST00000257659.8
ENST00000222511.6 ENST00000417207.1 |
GTPBP10
|
GTP-binding protein 10 (putative) |
| chr7_+_94536898 | 0.02 |
ENST00000433360.1
ENST00000340694.4 ENST00000424654.1 |
PPP1R9A
|
protein phosphatase 1, regulatory subunit 9A |
| chr10_-_105845674 | 0.02 |
ENST00000353479.5
ENST00000369733.3 |
COL17A1
|
collagen, type XVII, alpha 1 |
| chr8_-_72268968 | 0.01 |
ENST00000388740.3
|
EYA1
|
eyes absent homolog 1 (Drosophila) |
Network of associatons between targets according to the STRING database.
First level regulatory network of DPRX
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 9.3 | 260.4 | GO:0046597 | response to interferon-alpha(GO:0035455) negative regulation of viral entry into host cell(GO:0046597) |
| 2.0 | 6.1 | GO:0030241 | skeletal muscle myosin thick filament assembly(GO:0030241) |
| 1.6 | 6.3 | GO:1902544 | oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544) |
| 1.2 | 3.7 | GO:0030886 | negative regulation of myeloid dendritic cell activation(GO:0030886) |
| 1.2 | 13.0 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 0.8 | 2.3 | GO:0070171 | negative regulation of tooth mineralization(GO:0070171) |
| 0.7 | 2.7 | GO:1903224 | regulation of endodermal cell differentiation(GO:1903224) |
| 0.7 | 9.9 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.6 | 2.6 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 0.6 | 7.6 | GO:0051712 | positive regulation of killing of cells of other organism(GO:0051712) |
| 0.6 | 1.8 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
| 0.6 | 6.7 | GO:0001915 | negative regulation of T cell mediated cytotoxicity(GO:0001915) |
| 0.5 | 2.1 | GO:0001757 | somite specification(GO:0001757) |
| 0.5 | 1.5 | GO:0052027 | modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032) |
| 0.5 | 4.3 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) |
| 0.5 | 2.9 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
| 0.4 | 6.6 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
| 0.4 | 1.9 | GO:0001957 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.3 | 2.1 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 0.3 | 5.7 | GO:0001765 | membrane raft assembly(GO:0001765) |
| 0.3 | 7.7 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.3 | 4.9 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.3 | 7.1 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.3 | 1.8 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
| 0.3 | 4.0 | GO:0060056 | mammary gland involution(GO:0060056) |
| 0.3 | 1.1 | GO:1903936 | response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936) |
| 0.3 | 3.9 | GO:0071670 | smooth muscle cell chemotaxis(GO:0071670) |
| 0.3 | 0.8 | GO:0086092 | regulation of the force of heart contraction by cardiac conduction(GO:0086092) |
| 0.2 | 1.0 | GO:2000860 | positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860) |
| 0.2 | 3.2 | GO:0051014 | actin filament severing(GO:0051014) |
| 0.2 | 1.7 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.2 | 1.5 | GO:0006880 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 0.2 | 0.8 | GO:0072396 | response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) |
| 0.2 | 3.5 | GO:1901741 | positive regulation of myoblast fusion(GO:1901741) |
| 0.2 | 1.7 | GO:0030450 | regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027) |
| 0.2 | 5.5 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
| 0.2 | 6.5 | GO:0032456 | endocytic recycling(GO:0032456) |
| 0.2 | 0.6 | GO:0006663 | platelet activating factor biosynthetic process(GO:0006663) |
| 0.2 | 2.8 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 0.2 | 1.4 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.2 | 0.9 | GO:0001865 | NK T cell differentiation(GO:0001865) |
| 0.2 | 1.8 | GO:0043102 | amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267) |
| 0.1 | 0.8 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.1 | 1.7 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.1 | 2.0 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
| 0.1 | 0.9 | GO:1902255 | positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) |
| 0.1 | 2.6 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
| 0.1 | 1.2 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.1 | 0.3 | GO:2001190 | positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190) |
| 0.1 | 4.1 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.1 | 0.6 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.1 | 2.8 | GO:0022011 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
| 0.1 | 1.3 | GO:0006558 | L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222) |
| 0.1 | 1.0 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
| 0.1 | 5.1 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.1 | 2.4 | GO:0097352 | autophagosome maturation(GO:0097352) |
| 0.1 | 1.1 | GO:0032516 | positive regulation of phosphoprotein phosphatase activity(GO:0032516) |
| 0.1 | 1.2 | GO:0034315 | regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315) |
| 0.1 | 3.1 | GO:1901998 | toxin transport(GO:1901998) |
| 0.1 | 6.3 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
| 0.1 | 0.2 | GO:0036269 | swimming behavior(GO:0036269) |
| 0.1 | 0.6 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.1 | 0.6 | GO:0008272 | sulfate transport(GO:0008272) |
| 0.1 | 2.4 | GO:0071480 | cellular response to gamma radiation(GO:0071480) |
| 0.1 | 2.3 | GO:0006536 | glutamate metabolic process(GO:0006536) |
| 0.1 | 0.3 | GO:0072757 | cellular response to camptothecin(GO:0072757) |
| 0.1 | 4.5 | GO:0035690 | cellular response to drug(GO:0035690) |
| 0.1 | 1.0 | GO:2000696 | regulation of epithelial cell differentiation involved in kidney development(GO:2000696) |
| 0.1 | 1.0 | GO:0008535 | respiratory chain complex IV assembly(GO:0008535) |
| 0.1 | 2.3 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.0 | 0.7 | GO:0034656 | nucleobase-containing small molecule catabolic process(GO:0034656) |
| 0.0 | 0.5 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 0.0 | 0.5 | GO:0008212 | mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212) |
| 0.0 | 3.4 | GO:0033275 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.0 | 3.9 | GO:0050672 | negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672) |
| 0.0 | 1.7 | GO:0030513 | positive regulation of BMP signaling pathway(GO:0030513) |
| 0.0 | 0.2 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) |
| 0.0 | 1.4 | GO:0046785 | microtubule polymerization(GO:0046785) |
| 0.0 | 1.0 | GO:0033120 | positive regulation of RNA splicing(GO:0033120) |
| 0.0 | 0.9 | GO:0006349 | regulation of gene expression by genetic imprinting(GO:0006349) |
| 0.0 | 2.9 | GO:0006027 | glycosaminoglycan catabolic process(GO:0006027) |
| 0.0 | 0.8 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.0 | 1.5 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
| 0.0 | 0.2 | GO:0030581 | intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708) |
| 0.0 | 5.0 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 0.0 | 0.1 | GO:0044537 | regulation of circulating fibrinogen levels(GO:0044537) |
| 0.0 | 2.1 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.0 | 0.5 | GO:0060397 | JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397) |
| 0.0 | 3.3 | GO:0045727 | positive regulation of translation(GO:0045727) |
| 0.0 | 0.8 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.0 | 1.9 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.0 | 0.2 | GO:0006633 | fatty acid biosynthetic process(GO:0006633) |
| 0.0 | 0.6 | GO:0035987 | endodermal cell differentiation(GO:0035987) |
| 0.0 | 0.1 | GO:0008211 | glucocorticoid metabolic process(GO:0008211) |
| 0.0 | 3.0 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.0 | 0.6 | GO:0006368 | transcription elongation from RNA polymerase II promoter(GO:0006368) |
| 0.0 | 0.7 | GO:0061178 | regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.2 | 13.0 | GO:0072557 | IPAF inflammasome complex(GO:0072557) |
| 1.9 | 258.3 | GO:0031902 | late endosome membrane(GO:0031902) |
| 1.0 | 8.7 | GO:0044194 | cytolytic granule(GO:0044194) |
| 0.9 | 2.7 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.8 | 11.9 | GO:0030478 | actin cap(GO:0030478) |
| 0.6 | 7.7 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.6 | 7.0 | GO:0044754 | autolysosome(GO:0044754) |
| 0.4 | 5.7 | GO:0030663 | COPI-coated vesicle membrane(GO:0030663) |
| 0.4 | 3.1 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.3 | 4.9 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.3 | 1.9 | GO:0036021 | endolysosome lumen(GO:0036021) |
| 0.3 | 6.0 | GO:0030125 | clathrin vesicle coat(GO:0030125) |
| 0.3 | 3.4 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.3 | 6.3 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.2 | 6.1 | GO:0032982 | myosin filament(GO:0032982) |
| 0.2 | 6.8 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.2 | 1.0 | GO:0089701 | U2AF(GO:0089701) |
| 0.2 | 3.2 | GO:0032059 | bleb(GO:0032059) |
| 0.2 | 8.0 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.1 | 1.4 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.1 | 1.9 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.1 | 1.2 | GO:0016013 | syntrophin complex(GO:0016013) |
| 0.1 | 0.8 | GO:0030893 | meiotic cohesin complex(GO:0030893) |
| 0.1 | 3.2 | GO:0043218 | compact myelin(GO:0043218) |
| 0.1 | 5.0 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.1 | 0.8 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 0.1 | 4.3 | GO:0008305 | integrin complex(GO:0008305) |
| 0.1 | 0.5 | GO:0030868 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 0.1 | 2.3 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.1 | 9.5 | GO:0005604 | basement membrane(GO:0005604) |
| 0.1 | 2.4 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.1 | 2.4 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.1 | 1.8 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.1 | 3.5 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.1 | 1.0 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.1 | 7.0 | GO:0030175 | filopodium(GO:0030175) |
| 0.1 | 7.4 | GO:0016605 | PML body(GO:0016605) |
| 0.1 | 0.2 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.1 | 0.7 | GO:0097433 | dense body(GO:0097433) |
| 0.0 | 1.4 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.0 | 11.4 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 0.2 | GO:0036502 | Derlin-1-VIMP complex(GO:0036502) |
| 0.0 | 1.7 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 0.9 | GO:0030686 | 90S preribosome(GO:0030686) |
| 0.0 | 2.8 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 1.8 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) |
| 0.0 | 4.8 | GO:0019897 | extrinsic component of plasma membrane(GO:0019897) |
| 0.0 | 0.8 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.0 | 4.0 | GO:0101002 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.0 | 0.8 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 0.5 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.0 | 0.6 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.0 | 1.2 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 0.8 | GO:0031672 | A band(GO:0031672) |
| 0.0 | 2.8 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.0 | 0.1 | GO:0034464 | BBSome(GO:0034464) |
| 0.0 | 0.5 | GO:0031904 | endosome lumen(GO:0031904) |
| 0.0 | 0.9 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 1.0 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 1.4 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 0.6 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 0.8 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.0 | 0.8 | GO:0030315 | T-tubule(GO:0030315) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.2 | 6.7 | GO:0004917 | interleukin-7 receptor activity(GO:0004917) |
| 2.1 | 6.3 | GO:0043739 | G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739) |
| 0.9 | 13.0 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.6 | 1.8 | GO:0047150 | betaine-homocysteine S-methyltransferase activity(GO:0047150) |
| 0.5 | 2.3 | GO:0047820 | D-glutamate cyclase activity(GO:0047820) |
| 0.4 | 11.9 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.3 | 8.7 | GO:0022829 | wide pore channel activity(GO:0022829) |
| 0.3 | 1.3 | GO:0004505 | phenylalanine 4-monooxygenase activity(GO:0004505) |
| 0.3 | 2.0 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.2 | 6.1 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.2 | 1.0 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
| 0.2 | 3.4 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.2 | 3.0 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.2 | 2.1 | GO:0001730 | 2'-5'-oligoadenylate synthetase activity(GO:0001730) |
| 0.2 | 7.0 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.2 | 1.0 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
| 0.2 | 0.8 | GO:0036033 | mediator complex binding(GO:0036033) |
| 0.2 | 3.2 | GO:0005522 | profilin binding(GO:0005522) |
| 0.2 | 1.7 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.2 | 0.5 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) steroid delta-isomerase activity(GO:0004769) |
| 0.2 | 1.5 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.2 | 0.5 | GO:0005148 | prolactin receptor binding(GO:0005148) |
| 0.1 | 3.4 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.1 | 6.3 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 0.1 | 2.6 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 0.1 | 1.8 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.1 | 2.3 | GO:0008026 | RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) ATP-dependent helicase activity(GO:0008026) RNA-dependent ATPase activity(GO:0008186) purine NTP-dependent helicase activity(GO:0070035) |
| 0.1 | 1.2 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.1 | 1.7 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.1 | 4.0 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.1 | 0.5 | GO:0002046 | opsin binding(GO:0002046) |
| 0.1 | 0.5 | GO:0031013 | troponin I binding(GO:0031013) |
| 0.1 | 2.9 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.1 | 0.9 | GO:1990948 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
| 0.1 | 5.0 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.1 | 2.4 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.1 | 1.9 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
| 0.1 | 0.2 | GO:0004320 | oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297) |
| 0.1 | 0.6 | GO:0008271 | secondary active sulfate transmembrane transporter activity(GO:0008271) |
| 0.1 | 2.9 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.1 | 2.1 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.1 | 0.8 | GO:0015385 | sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
| 0.1 | 5.2 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.1 | 1.7 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.1 | 0.6 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.1 | 0.7 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.1 | 0.6 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.1 | 1.5 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.1 | 0.5 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
| 0.1 | 0.7 | GO:0017110 | nucleoside-diphosphatase activity(GO:0017110) |
| 0.0 | 6.0 | GO:0003774 | motor activity(GO:0003774) |
| 0.0 | 0.2 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
| 0.0 | 0.4 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
| 0.0 | 1.3 | GO:0061659 | ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659) |
| 0.0 | 2.1 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.0 | 0.2 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.0 | 1.5 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.0 | 0.8 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.0 | 1.3 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 5.5 | GO:0008201 | heparin binding(GO:0008201) |
| 0.0 | 0.5 | GO:0008320 | protein transmembrane transporter activity(GO:0008320) |
| 0.0 | 3.3 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.0 | 6.6 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.0 | 1.9 | GO:0030295 | protein kinase activator activity(GO:0030295) |
| 0.0 | 2.7 | GO:0046332 | SMAD binding(GO:0046332) |
| 0.0 | 1.8 | GO:0005244 | voltage-gated ion channel activity(GO:0005244) voltage-gated channel activity(GO:0022832) |
| 0.0 | 8.1 | GO:0005525 | GTP binding(GO:0005525) |
| 0.0 | 0.2 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 0.0 | 0.2 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 1.4 | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
| 0.0 | 170.3 | GO:0005515 | protein binding(GO:0005515) |
| 0.0 | 1.0 | GO:0003823 | antigen binding(GO:0003823) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 8.7 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.3 | 20.9 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.2 | 7.1 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.1 | 8.8 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.1 | 4.2 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.1 | 4.5 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 4.1 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.1 | 7.8 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 5.3 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.1 | 2.7 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.1 | 1.3 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.1 | 0.9 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.0 | 1.1 | PID HIV NEF PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
| 0.0 | 2.9 | PID ATR PATHWAY | ATR signaling pathway |
| 0.0 | 1.7 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.0 | 1.7 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 5.2 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 0.6 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.0 | 1.7 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 0.8 | PID RHOA PATHWAY | RhoA signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.9 | 262.5 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.3 | 21.4 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.3 | 5.9 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.3 | 8.8 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.3 | 3.1 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.3 | 5.6 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.2 | 11.2 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.2 | 2.9 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.1 | 1.9 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.1 | 2.9 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.1 | 2.6 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.1 | 8.9 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.1 | 6.6 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.1 | 0.6 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.1 | 2.1 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.1 | 3.0 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.1 | 1.5 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 | Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1) |
| 0.1 | 1.7 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.0 | 3.9 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 1.9 | REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
| 0.0 | 2.7 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 0.6 | REACTOME ACYL CHAIN REMODELLING OF PG | Genes involved in Acyl chain remodelling of PG |
| 0.0 | 0.8 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.0 | 3.5 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 0.0 | 1.2 | REACTOME MUSCLE CONTRACTION | Genes involved in Muscle contraction |
| 0.0 | 1.0 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.0 | 0.5 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.0 | 0.2 | REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G | Genes involved in Vif-mediated degradation of APOBEC3G |
| 0.0 | 0.2 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |