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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
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Results for EGR1_EGR4
Z-value: 0.54
Motif logo
Transcription factors associated with EGR1_EGR4
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
EGR1
|
ENSG00000120738.7 | early growth response 1 |
|
EGR4
|
ENSG00000135625.6 | early growth response 4 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| EGR1 | hg19_v2_chr5_+_137801160_137801179 | 0.36 | 4.5e-08 | Click! |
| EGR4 | hg19_v2_chr2_-_73520667_73520833 | 0.18 | 8.2e-03 | Click! |
Activity profile of EGR1_EGR4 motif
Sorted Z-values of EGR1_EGR4 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of EGR1_EGR4
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.2 | 12.5 | GO:1902595 | regulation of DNA replication origin binding(GO:1902595) |
| 4.1 | 12.2 | GO:0071409 | cellular response to cycloheximide(GO:0071409) |
| 3.9 | 11.7 | GO:1990108 | protein linear deubiquitination(GO:1990108) |
| 3.8 | 11.4 | GO:0035408 | histone H3-T6 phosphorylation(GO:0035408) |
| 3.2 | 12.8 | GO:0001743 | optic placode formation(GO:0001743) |
| 2.5 | 7.5 | GO:1990922 | regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922) |
| 2.4 | 7.2 | GO:2000182 | regulation of progesterone biosynthetic process(GO:2000182) |
| 2.1 | 8.3 | GO:0072237 | metanephric proximal tubule development(GO:0072237) |
| 1.9 | 5.7 | GO:1901341 | activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341) |
| 1.6 | 4.9 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
| 1.6 | 6.5 | GO:0031339 | negative regulation of vesicle fusion(GO:0031339) |
| 1.6 | 25.7 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
| 1.6 | 4.8 | GO:0090187 | positive regulation of pancreatic juice secretion(GO:0090187) |
| 1.5 | 3.0 | GO:0070434 | positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434) |
| 1.4 | 2.9 | GO:0008286 | insulin receptor signaling pathway(GO:0008286) |
| 1.4 | 4.2 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
| 1.4 | 8.2 | GO:0071321 | cellular response to cGMP(GO:0071321) |
| 1.4 | 5.4 | GO:0045085 | negative regulation of interleukin-2 biosynthetic process(GO:0045085) regulation of polynucleotide adenylyltransferase activity(GO:1904245) |
| 1.3 | 3.8 | GO:0031133 | regulation of axon diameter(GO:0031133) |
| 1.3 | 6.3 | GO:0007521 | muscle cell fate determination(GO:0007521) |
| 1.2 | 3.7 | GO:0034146 | toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) negative regulation of osteoclast proliferation(GO:0090291) |
| 1.2 | 6.1 | GO:2000035 | regulation of stem cell division(GO:2000035) |
| 1.2 | 4.9 | GO:0003335 | corneocyte development(GO:0003335) |
| 1.2 | 3.6 | GO:0051595 | response to methylglyoxal(GO:0051595) |
| 1.2 | 9.5 | GO:2000467 | positive regulation of glycogen (starch) synthase activity(GO:2000467) |
| 1.2 | 4.7 | GO:0072674 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
| 1.1 | 5.7 | GO:0071895 | odontoblast differentiation(GO:0071895) |
| 1.1 | 3.4 | GO:0071529 | cementum mineralization(GO:0071529) |
| 1.1 | 5.5 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
| 1.1 | 6.5 | GO:1900239 | phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239) |
| 1.1 | 6.4 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
| 1.0 | 4.2 | GO:1902723 | negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) |
| 1.0 | 2.0 | GO:0072014 | proximal tubule development(GO:0072014) |
| 1.0 | 3.0 | GO:0045994 | positive regulation of translational initiation by iron(GO:0045994) |
| 1.0 | 2.9 | GO:1900169 | regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
| 1.0 | 2.0 | GO:1905064 | negative regulation of vascular smooth muscle cell differentiation(GO:1905064) |
| 1.0 | 2.9 | GO:0051697 | protein delipidation(GO:0051697) |
| 1.0 | 9.6 | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
| 0.9 | 2.8 | GO:0001649 | osteoblast differentiation(GO:0001649) |
| 0.9 | 7.5 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 0.9 | 2.8 | GO:0006982 | response to lipid hydroperoxide(GO:0006982) |
| 0.9 | 1.8 | GO:0002537 | nitric oxide production involved in inflammatory response(GO:0002537) |
| 0.9 | 2.8 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 0.9 | 12.7 | GO:1903830 | magnesium ion transmembrane transport(GO:1903830) |
| 0.9 | 10.0 | GO:0070561 | vitamin D receptor signaling pathway(GO:0070561) |
| 0.9 | 1.8 | GO:0051085 | 'de novo' posttranslational protein folding(GO:0051084) chaperone mediated protein folding requiring cofactor(GO:0051085) |
| 0.9 | 4.5 | GO:1902202 | regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) |
| 0.9 | 3.5 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
| 0.9 | 5.2 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.9 | 5.2 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
| 0.9 | 2.6 | GO:0001544 | initiation of primordial ovarian follicle growth(GO:0001544) |
| 0.9 | 1.7 | GO:0032058 | positive regulation of translational initiation in response to stress(GO:0032058) |
| 0.8 | 9.3 | GO:0000050 | urea cycle(GO:0000050) |
| 0.8 | 2.5 | GO:0090219 | negative regulation of lipid kinase activity(GO:0090219) |
| 0.8 | 2.5 | GO:0010286 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 0.8 | 5.0 | GO:1904381 | Golgi apparatus mannose trimming(GO:1904381) |
| 0.8 | 0.8 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) |
| 0.8 | 2.4 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
| 0.8 | 10.3 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 0.8 | 2.3 | GO:0035359 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) |
| 0.8 | 2.3 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 0.8 | 3.1 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
| 0.8 | 6.1 | GO:2000344 | positive regulation of acrosome reaction(GO:2000344) |
| 0.8 | 1.5 | GO:1903521 | apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747) |
| 0.8 | 1.5 | GO:0014022 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
| 0.7 | 10.2 | GO:0098719 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.7 | 20.1 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.7 | 2.1 | GO:0070105 | regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105) |
| 0.7 | 9.2 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.7 | 2.8 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
| 0.7 | 2.1 | GO:0097327 | response to antineoplastic agent(GO:0097327) |
| 0.7 | 1.4 | GO:0048382 | mesendoderm development(GO:0048382) |
| 0.7 | 2.0 | GO:0006014 | D-ribose metabolic process(GO:0006014) |
| 0.7 | 6.0 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
| 0.7 | 2.6 | GO:0060623 | regulation of chromosome condensation(GO:0060623) |
| 0.7 | 0.7 | GO:1902303 | negative regulation of potassium ion export(GO:1902303) |
| 0.6 | 5.2 | GO:1902525 | regulation of protein monoubiquitination(GO:1902525) |
| 0.6 | 2.6 | GO:0000430 | regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) |
| 0.6 | 1.9 | GO:0019417 | sulfur oxidation(GO:0019417) |
| 0.6 | 1.3 | GO:2000705 | dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705) |
| 0.6 | 3.2 | GO:0045626 | negative regulation of T-helper 1 cell differentiation(GO:0045626) response to odorant(GO:1990834) |
| 0.6 | 1.9 | GO:0003358 | noradrenergic neuron development(GO:0003358) |
| 0.6 | 1.8 | GO:0010957 | negative regulation of vitamin D biosynthetic process(GO:0010957) |
| 0.6 | 3.7 | GO:0042670 | retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) |
| 0.6 | 1.7 | GO:0060061 | Spemann organizer formation(GO:0060061) |
| 0.6 | 3.4 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.6 | 1.7 | GO:0038193 | thromboxane A2 signaling pathway(GO:0038193) |
| 0.6 | 1.7 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 0.6 | 3.9 | GO:2000049 | positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049) |
| 0.5 | 3.3 | GO:0070172 | positive regulation of tooth mineralization(GO:0070172) |
| 0.5 | 1.6 | GO:0045212 | negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212) |
| 0.5 | 4.3 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
| 0.5 | 1.6 | GO:1990737 | regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) response to manganese-induced endoplasmic reticulum stress(GO:1990737) |
| 0.5 | 3.2 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
| 0.5 | 2.1 | GO:1904048 | regulation of spontaneous neurotransmitter secretion(GO:1904048) |
| 0.5 | 2.1 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
| 0.5 | 2.0 | GO:0042418 | epinephrine biosynthetic process(GO:0042418) |
| 0.5 | 3.6 | GO:0050893 | sensory processing(GO:0050893) |
| 0.5 | 4.0 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
| 0.5 | 2.0 | GO:1903691 | positive regulation of wound healing, spreading of epidermal cells(GO:1903691) |
| 0.5 | 3.0 | GO:0034128 | negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128) |
| 0.5 | 1.5 | GO:0050434 | positive regulation of viral transcription(GO:0050434) |
| 0.5 | 1.0 | GO:0016080 | synaptic vesicle targeting(GO:0016080) |
| 0.5 | 3.4 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.5 | 2.5 | GO:0014835 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) |
| 0.5 | 2.4 | GO:0036369 | transcription factor catabolic process(GO:0036369) |
| 0.5 | 2.4 | GO:0021586 | pons maturation(GO:0021586) |
| 0.5 | 1.4 | GO:0098935 | dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) |
| 0.5 | 8.1 | GO:0034063 | stress granule assembly(GO:0034063) |
| 0.5 | 0.5 | GO:0006680 | glucosylceramide catabolic process(GO:0006680) |
| 0.5 | 1.9 | GO:1903960 | regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) |
| 0.5 | 5.2 | GO:0032025 | response to cobalt ion(GO:0032025) |
| 0.5 | 40.3 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
| 0.5 | 0.9 | GO:0071677 | positive regulation of mononuclear cell migration(GO:0071677) |
| 0.5 | 2.3 | GO:0045824 | negative regulation of innate immune response(GO:0045824) |
| 0.5 | 1.4 | GO:0098528 | skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809) |
| 0.5 | 9.1 | GO:0031167 | rRNA methylation(GO:0031167) |
| 0.5 | 1.8 | GO:0072166 | posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) regulation of metanephric glomerular mesangial cell proliferation(GO:0072301) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) |
| 0.5 | 0.5 | GO:1901420 | negative regulation of response to alcohol(GO:1901420) |
| 0.5 | 5.0 | GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440) |
| 0.4 | 1.8 | GO:2000969 | positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969) |
| 0.4 | 2.2 | GO:0030538 | embryonic genitalia morphogenesis(GO:0030538) |
| 0.4 | 1.3 | GO:0003342 | proepicardium development(GO:0003342) septum transversum development(GO:0003343) |
| 0.4 | 3.9 | GO:1902949 | positive regulation of tau-protein kinase activity(GO:1902949) |
| 0.4 | 7.3 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 0.4 | 3.8 | GO:0014877 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.4 | 1.3 | GO:1904924 | negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924) |
| 0.4 | 1.7 | GO:0044026 | DNA hypermethylation(GO:0044026) |
| 0.4 | 2.1 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
| 0.4 | 1.2 | GO:0038163 | thrombopoietin-mediated signaling pathway(GO:0038163) |
| 0.4 | 1.7 | GO:0001994 | norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994) |
| 0.4 | 5.3 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 0.4 | 1.2 | GO:1900224 | positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) |
| 0.4 | 1.6 | GO:0002032 | desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032) |
| 0.4 | 1.6 | GO:0019046 | release from viral latency(GO:0019046) |
| 0.4 | 4.3 | GO:0039536 | negative regulation of RIG-I signaling pathway(GO:0039536) |
| 0.4 | 1.2 | GO:0070634 | transepithelial ammonium transport(GO:0070634) |
| 0.4 | 2.7 | GO:1902746 | regulation of lens fiber cell differentiation(GO:1902746) |
| 0.4 | 1.2 | GO:1903926 | signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926) |
| 0.4 | 1.1 | GO:0036466 | synaptic vesicle recycling via endosome(GO:0036466) |
| 0.4 | 0.4 | GO:0085020 | protein K29-linked ubiquitination(GO:0035519) protein K27-linked ubiquitination(GO:0044314) protein K6-linked ubiquitination(GO:0085020) |
| 0.4 | 1.1 | GO:0035441 | cell migration involved in vasculogenesis(GO:0035441) |
| 0.4 | 1.9 | GO:1901098 | regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098) |
| 0.4 | 2.6 | GO:0035093 | spermatogenesis, exchange of chromosomal proteins(GO:0035093) |
| 0.4 | 1.1 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
| 0.4 | 1.5 | GO:0002317 | plasma cell differentiation(GO:0002317) |
| 0.4 | 4.4 | GO:0071243 | cellular response to arsenic-containing substance(GO:0071243) |
| 0.4 | 6.1 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
| 0.4 | 4.3 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
| 0.3 | 3.5 | GO:1903025 | regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025) |
| 0.3 | 0.7 | GO:1900425 | negative regulation of defense response to bacterium(GO:1900425) |
| 0.3 | 3.4 | GO:0045054 | constitutive secretory pathway(GO:0045054) |
| 0.3 | 1.4 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) ERK5 cascade(GO:0070375) |
| 0.3 | 1.0 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
| 0.3 | 2.3 | GO:0021842 | directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) |
| 0.3 | 2.3 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.3 | 10.4 | GO:0006783 | heme biosynthetic process(GO:0006783) |
| 0.3 | 12.0 | GO:0090022 | regulation of neutrophil chemotaxis(GO:0090022) |
| 0.3 | 3.6 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 0.3 | 4.3 | GO:0097150 | neuronal stem cell population maintenance(GO:0097150) |
| 0.3 | 1.3 | GO:1900107 | regulation of nodal signaling pathway(GO:1900107) |
| 0.3 | 2.0 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.3 | 1.0 | GO:0021913 | regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) |
| 0.3 | 1.3 | GO:1903721 | regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721) |
| 0.3 | 1.0 | GO:0034184 | positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) |
| 0.3 | 5.1 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.3 | 1.6 | GO:0003431 | growth plate cartilage chondrocyte growth(GO:0003430) growth plate cartilage chondrocyte development(GO:0003431) Harderian gland development(GO:0070384) |
| 0.3 | 1.3 | GO:0046013 | T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013) |
| 0.3 | 1.6 | GO:1904628 | response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628) |
| 0.3 | 0.6 | GO:0009450 | gamma-aminobutyric acid catabolic process(GO:0009450) |
| 0.3 | 3.1 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 0.3 | 5.0 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.3 | 1.5 | GO:0090245 | axis elongation involved in somitogenesis(GO:0090245) |
| 0.3 | 1.2 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
| 0.3 | 1.2 | GO:0007386 | compartment pattern specification(GO:0007386) |
| 0.3 | 1.8 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.3 | 1.5 | GO:0051414 | response to cortisol(GO:0051414) |
| 0.3 | 1.5 | GO:0072021 | ascending thin limb development(GO:0072021) metanephric ascending thin limb development(GO:0072218) |
| 0.3 | 2.1 | GO:0050910 | detection of mechanical stimulus involved in sensory perception of sound(GO:0050910) |
| 0.3 | 3.6 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
| 0.3 | 1.8 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.3 | 0.9 | GO:1903526 | negative regulation of membrane tubulation(GO:1903526) |
| 0.3 | 9.1 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.3 | 9.0 | GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
| 0.3 | 2.3 | GO:1902951 | negative regulation of dendritic spine maintenance(GO:1902951) |
| 0.3 | 1.4 | GO:0048165 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) |
| 0.3 | 2.9 | GO:0060019 | radial glial cell differentiation(GO:0060019) |
| 0.3 | 5.2 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.3 | 4.0 | GO:0043589 | skin morphogenesis(GO:0043589) |
| 0.3 | 2.6 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
| 0.3 | 1.1 | GO:0002572 | pro-T cell differentiation(GO:0002572) |
| 0.3 | 7.6 | GO:0048935 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 0.3 | 1.1 | GO:1900738 | regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) |
| 0.3 | 2.5 | GO:1901998 | toxin transport(GO:1901998) |
| 0.3 | 1.7 | GO:0072103 | glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104) |
| 0.3 | 2.2 | GO:1903546 | protein localization to photoreceptor outer segment(GO:1903546) |
| 0.3 | 1.1 | GO:0002268 | follicular dendritic cell differentiation(GO:0002268) |
| 0.3 | 2.2 | GO:0002326 | B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152) |
| 0.3 | 1.3 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 0.3 | 1.3 | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) |
| 0.3 | 5.8 | GO:2000178 | negative regulation of neural precursor cell proliferation(GO:2000178) |
| 0.3 | 3.1 | GO:0007512 | adult heart development(GO:0007512) |
| 0.3 | 3.1 | GO:1900103 | positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103) |
| 0.3 | 2.1 | GO:0016926 | protein desumoylation(GO:0016926) |
| 0.3 | 0.5 | GO:2000382 | positive regulation of mesoderm development(GO:2000382) |
| 0.3 | 1.0 | GO:0009648 | photoperiodism(GO:0009648) entrainment of circadian clock(GO:0009649) entrainment of circadian clock by photoperiod(GO:0043153) |
| 0.2 | 1.2 | GO:2000468 | negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470) |
| 0.2 | 1.5 | GO:0010694 | positive regulation of alkaline phosphatase activity(GO:0010694) |
| 0.2 | 1.2 | GO:0070091 | glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092) |
| 0.2 | 0.5 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
| 0.2 | 1.4 | GO:0052551 | response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565) |
| 0.2 | 2.1 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
| 0.2 | 3.7 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.2 | 1.1 | GO:0034334 | adherens junction maintenance(GO:0034334) |
| 0.2 | 5.0 | GO:0001702 | gastrulation with mouth forming second(GO:0001702) |
| 0.2 | 1.8 | GO:0033578 | protein glycosylation in Golgi(GO:0033578) |
| 0.2 | 13.1 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
| 0.2 | 2.4 | GO:0060252 | positive regulation of glial cell proliferation(GO:0060252) |
| 0.2 | 3.5 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.2 | 0.2 | GO:0045541 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
| 0.2 | 2.5 | GO:0080182 | histone H3-K4 trimethylation(GO:0080182) |
| 0.2 | 0.6 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 0.2 | 1.9 | GO:0034465 | response to carbon monoxide(GO:0034465) |
| 0.2 | 0.8 | GO:1905232 | cellular response to L-glutamate(GO:1905232) |
| 0.2 | 2.9 | GO:0008340 | determination of adult lifespan(GO:0008340) |
| 0.2 | 0.4 | GO:0035900 | response to isolation stress(GO:0035900) |
| 0.2 | 6.4 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
| 0.2 | 3.4 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.2 | 2.2 | GO:0051823 | regulation of synapse structural plasticity(GO:0051823) |
| 0.2 | 3.0 | GO:0006346 | methylation-dependent chromatin silencing(GO:0006346) |
| 0.2 | 1.0 | GO:0009137 | purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181) |
| 0.2 | 2.8 | GO:0070734 | histone H3-K27 methylation(GO:0070734) |
| 0.2 | 1.6 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.2 | 2.6 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
| 0.2 | 3.4 | GO:0032292 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
| 0.2 | 0.6 | GO:0070407 | oxidation-dependent protein catabolic process(GO:0070407) |
| 0.2 | 4.9 | GO:0097503 | sialylation(GO:0097503) |
| 0.2 | 0.8 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 0.2 | 4.9 | GO:0010039 | response to iron ion(GO:0010039) |
| 0.2 | 0.9 | GO:0023041 | neuronal signal transduction(GO:0023041) |
| 0.2 | 1.1 | GO:0043320 | natural killer cell degranulation(GO:0043320) |
| 0.2 | 1.1 | GO:0036289 | peptidyl-serine autophosphorylation(GO:0036289) |
| 0.2 | 7.5 | GO:0006198 | cAMP catabolic process(GO:0006198) |
| 0.2 | 1.7 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 0.2 | 0.6 | GO:0050916 | sensory perception of sweet taste(GO:0050916) |
| 0.2 | 0.5 | GO:0032954 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
| 0.2 | 6.4 | GO:0007257 | activation of JUN kinase activity(GO:0007257) |
| 0.2 | 2.2 | GO:0051451 | myoblast migration(GO:0051451) |
| 0.2 | 2.7 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.2 | 2.5 | GO:0033127 | regulation of histone phosphorylation(GO:0033127) |
| 0.2 | 1.6 | GO:0048842 | positive regulation of axon extension involved in axon guidance(GO:0048842) |
| 0.2 | 0.9 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
| 0.2 | 1.2 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
| 0.2 | 2.4 | GO:0007520 | myoblast fusion(GO:0007520) |
| 0.2 | 2.4 | GO:0060044 | negative regulation of cardiac muscle cell proliferation(GO:0060044) |
| 0.2 | 1.7 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 0.2 | 6.6 | GO:0036465 | synaptic vesicle recycling(GO:0036465) |
| 0.2 | 0.8 | GO:0097113 | AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) |
| 0.2 | 4.3 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
| 0.2 | 0.7 | GO:0060084 | positive regulation of transmission of nerve impulse(GO:0051971) synaptic transmission involved in micturition(GO:0060084) |
| 0.2 | 3.9 | GO:0042753 | positive regulation of circadian rhythm(GO:0042753) |
| 0.2 | 3.4 | GO:0010719 | negative regulation of epithelial to mesenchymal transition(GO:0010719) |
| 0.2 | 3.8 | GO:0097502 | mannosylation(GO:0097502) |
| 0.2 | 1.9 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
| 0.2 | 0.6 | GO:1901184 | regulation of ERBB signaling pathway(GO:1901184) |
| 0.2 | 0.8 | GO:0044351 | macropinocytosis(GO:0044351) |
| 0.2 | 1.1 | GO:0032097 | positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100) |
| 0.1 | 6.1 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
| 0.1 | 1.9 | GO:0007034 | vacuolar transport(GO:0007034) |
| 0.1 | 2.3 | GO:0007413 | axonal fasciculation(GO:0007413) |
| 0.1 | 0.4 | GO:0006423 | cysteinyl-tRNA aminoacylation(GO:0006423) |
| 0.1 | 1.0 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.1 | 0.7 | GO:0015842 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) |
| 0.1 | 1.4 | GO:0043584 | nose development(GO:0043584) |
| 0.1 | 1.4 | GO:0070307 | lens fiber cell development(GO:0070307) |
| 0.1 | 1.5 | GO:0006024 | aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024) |
| 0.1 | 1.9 | GO:0060644 | mammary gland epithelial cell differentiation(GO:0060644) |
| 0.1 | 1.5 | GO:0071394 | cellular response to testosterone stimulus(GO:0071394) |
| 0.1 | 0.9 | GO:0071374 | cellular response to parathyroid hormone stimulus(GO:0071374) |
| 0.1 | 0.3 | GO:0090234 | regulation of kinetochore assembly(GO:0090234) |
| 0.1 | 0.7 | GO:0001992 | regulation of systemic arterial blood pressure by vasopressin(GO:0001992) |
| 0.1 | 0.7 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
| 0.1 | 1.2 | GO:0048245 | eosinophil chemotaxis(GO:0048245) |
| 0.1 | 1.1 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 0.1 | 0.7 | GO:0046959 | habituation(GO:0046959) |
| 0.1 | 0.8 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
| 0.1 | 2.1 | GO:0010172 | embryonic body morphogenesis(GO:0010172) |
| 0.1 | 2.6 | GO:0006972 | hyperosmotic response(GO:0006972) |
| 0.1 | 1.1 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
| 0.1 | 2.0 | GO:0099500 | synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500) |
| 0.1 | 1.0 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.1 | 0.2 | GO:1903348 | positive regulation of bicellular tight junction assembly(GO:1903348) |
| 0.1 | 0.5 | GO:0015910 | peroxisomal long-chain fatty acid import(GO:0015910) |
| 0.1 | 1.4 | GO:0045921 | positive regulation of exocytosis(GO:0045921) |
| 0.1 | 0.7 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
| 0.1 | 2.5 | GO:0071218 | cellular response to misfolded protein(GO:0071218) |
| 0.1 | 1.4 | GO:0050885 | neuromuscular process controlling balance(GO:0050885) |
| 0.1 | 1.0 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
| 0.1 | 1.4 | GO:0060670 | branching involved in labyrinthine layer morphogenesis(GO:0060670) |
| 0.1 | 2.5 | GO:1904380 | endoplasmic reticulum mannose trimming(GO:1904380) |
| 0.1 | 0.7 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.1 | 3.6 | GO:0001510 | RNA methylation(GO:0001510) |
| 0.1 | 1.4 | GO:0050775 | positive regulation of dendrite morphogenesis(GO:0050775) |
| 0.1 | 0.8 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.1 | 0.2 | GO:0042415 | norepinephrine metabolic process(GO:0042415) |
| 0.1 | 0.4 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
| 0.1 | 0.8 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
| 0.1 | 0.7 | GO:0042711 | maternal behavior(GO:0042711) parental behavior(GO:0060746) |
| 0.1 | 2.5 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
| 0.1 | 1.6 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.1 | 2.3 | GO:0002244 | hematopoietic progenitor cell differentiation(GO:0002244) |
| 0.1 | 0.2 | GO:0044065 | regulation of respiratory gaseous exchange(GO:0043576) regulation of respiratory system process(GO:0044065) |
| 0.1 | 1.1 | GO:0010667 | negative regulation of cardiac muscle cell apoptotic process(GO:0010667) |
| 0.1 | 0.8 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 0.1 | 5.0 | GO:0030279 | negative regulation of ossification(GO:0030279) |
| 0.1 | 0.6 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.1 | 1.4 | GO:0009299 | mRNA transcription(GO:0009299) |
| 0.1 | 1.3 | GO:0001573 | ganglioside metabolic process(GO:0001573) |
| 0.1 | 3.9 | GO:1902230 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230) |
| 0.1 | 0.3 | GO:0045807 | positive regulation of endocytosis(GO:0045807) |
| 0.1 | 0.5 | GO:0030382 | sperm mitochondrion organization(GO:0030382) |
| 0.1 | 0.5 | GO:0072502 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.1 | 1.9 | GO:0006853 | carnitine shuttle(GO:0006853) |
| 0.1 | 1.6 | GO:0030324 | lung development(GO:0030324) |
| 0.1 | 1.6 | GO:0043243 | positive regulation of protein complex disassembly(GO:0043243) |
| 0.1 | 0.9 | GO:0031124 | mRNA 3'-end processing(GO:0031124) RNA polyadenylation(GO:0043631) |
| 0.1 | 0.8 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 0.1 | 1.7 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.1 | 0.3 | GO:2001140 | regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140) |
| 0.1 | 0.5 | GO:0002024 | diet induced thermogenesis(GO:0002024) |
| 0.1 | 0.5 | GO:0051024 | positive regulation of immunoglobulin secretion(GO:0051024) |
| 0.1 | 2.7 | GO:0070884 | regulation of calcineurin-NFAT signaling cascade(GO:0070884) |
| 0.1 | 4.3 | GO:0043550 | regulation of lipid kinase activity(GO:0043550) |
| 0.1 | 0.6 | GO:0014722 | regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.1 | 0.3 | GO:0032383 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
| 0.1 | 1.4 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.1 | 0.8 | GO:0035461 | vitamin transmembrane transport(GO:0035461) |
| 0.1 | 0.8 | GO:0023019 | signal transduction involved in regulation of gene expression(GO:0023019) |
| 0.1 | 0.4 | GO:1901911 | diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
| 0.1 | 1.4 | GO:0045717 | negative regulation of fatty acid biosynthetic process(GO:0045717) |
| 0.1 | 1.3 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.1 | 0.7 | GO:0060087 | relaxation of vascular smooth muscle(GO:0060087) |
| 0.1 | 1.6 | GO:0008630 |