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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for FOXD3_FOXI1_FOXF1

Z-value: 0.56

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Transcription factors associated with FOXD3_FOXI1_FOXF1

Gene Symbol Gene ID Gene Info
ENSG00000187140.4 forkhead box D3
ENSG00000168269.7 forkhead box I1
ENSG00000103241.5 forkhead box F1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXI1hg19_v2_chr5_+_169532896_1695329170.092.0e-01Click!
FOXD3hg19_v2_chr1_+_63788730_637887300.027.7e-01Click!
FOXF1hg19_v2_chr16_+_86544113_86544145-0.018.9e-01Click!

Activity profile of FOXD3_FOXI1_FOXF1 motif

Sorted Z-values of FOXD3_FOXI1_FOXF1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_153303658 21.82 ENST00000296555.5
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr4_+_158142750 18.95 ENST00000505888.1
ENST00000449365.1
glutamate receptor, ionotropic, AMPA 2
chr11_-_111781610 14.57 ENST00000525823.1
crystallin, alpha B
chr5_-_88179302 14.25 ENST00000504921.2
myocyte enhancer factor 2C
chr4_+_71587669 12.23 ENST00000381006.3
ENST00000226328.4
RUN and FYVE domain containing 3
chr3_+_50712672 12.18 ENST00000266037.9
dedicator of cytokinesis 3
chr11_-_111781454 12.08 ENST00000533280.1
crystallin, alpha B
chr11_-_111781554 11.78 ENST00000526167.1
ENST00000528961.1
crystallin, alpha B
chr5_-_146302078 11.06 ENST00000508545.2
protein phosphatase 2, regulatory subunit B, beta
chr17_-_29641084 10.89 ENST00000544462.1
ecotropic viral integration site 2B
chr5_+_173472607 10.84 ENST00000303177.3
ENST00000519867.1
Neuron-specific protein family member 2
chr7_+_86273218 10.54 ENST00000361669.2
glutamate receptor, metabotropic 3
chr16_+_6069586 10.31 ENST00000547372.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr12_+_79439405 10.02 ENST00000552744.1
synaptotagmin I
chr2_-_2334888 9.96 ENST00000428368.2
ENST00000399161.2
myelin transcription factor 1-like
chr1_+_10292308 9.89 ENST00000377081.1
kinesin family member 1B
chr6_-_152639479 9.80 ENST00000356820.4
spectrin repeat containing, nuclear envelope 1
chr4_-_84035905 9.20 ENST00000311507.4
placenta-specific 8
chr5_-_176057365 9.17 ENST00000310112.3
synuclein, beta
chr4_-_84035868 9.08 ENST00000426923.2
ENST00000509973.1
placenta-specific 8
chr6_+_31582961 9.05 ENST00000376059.3
ENST00000337917.7
allograft inflammatory factor 1
chr3_-_195310802 9.04 ENST00000421243.1
ENST00000453131.1
apolipoprotein D
chr7_-_37026108 8.80 ENST00000396045.3
engulfment and cell motility 1
chr5_-_176056974 8.79 ENST00000510387.1
ENST00000506696.1
synuclein, beta
chr12_+_10365404 8.77 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABA(A) receptor-associated protein like 1
chr18_-_53070913 8.55 ENST00000568186.1
ENST00000564228.1
transcription factor 4
chr17_-_29641104 8.46 ENST00000577894.1
ENST00000330927.4
ecotropic viral integration site 2B
chr3_+_35721106 8.42 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
cAMP-regulated phosphoprotein, 21kDa
chr1_-_27952741 7.81 ENST00000399173.1
feline Gardner-Rasheed sarcoma viral oncogene homolog
chr6_-_133084580 7.66 ENST00000525270.1
ENST00000530536.1
ENST00000524919.1
vanin 2
chr2_-_175711133 7.42 ENST00000409597.1
ENST00000413882.1
chimerin 1
chr10_+_95517660 7.34 ENST00000371413.3
leucine-rich, glioma inactivated 1
chr5_+_156712372 7.31 ENST00000541131.1
cytoplasmic FMR1 interacting protein 2
chr5_-_172198190 7.28 ENST00000239223.3
dual specificity phosphatase 1
chr5_-_24645078 7.12 ENST00000264463.4
cadherin 10, type 2 (T2-cadherin)
chr3_-_127455200 6.78 ENST00000398101.3
monoglyceride lipase
chr2_+_166095898 6.73 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
sodium channel, voltage-gated, type II, alpha subunit
chr7_-_37488834 6.68 ENST00000310758.4
engulfment and cell motility 1
chr14_+_23299088 6.51 ENST00000355151.5
ENST00000397496.3
ENST00000555345.1
ENST00000432849.3
ENST00000553711.1
ENST00000556465.1
ENST00000397505.2
ENST00000557221.1
ENST00000311892.6
ENST00000556840.1
ENST00000555536.1
mitochondrial ribosomal protein L52
chr3_-_16524357 6.50 ENST00000432519.1
raftlin, lipid raft linker 1
chr6_-_152489484 6.48 ENST00000354674.4
ENST00000539504.1
spectrin repeat containing, nuclear envelope 1
chr16_+_6069072 6.27 ENST00000547605.1
ENST00000550418.1
ENST00000553186.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr3_+_39509163 6.13 ENST00000436143.2
ENST00000441980.2
ENST00000311042.6
myelin-associated oligodendrocyte basic protein
chr3_+_39509070 5.72 ENST00000354668.4
ENST00000428261.1
ENST00000420739.1
ENST00000415443.1
ENST00000447324.1
ENST00000383754.3
myelin-associated oligodendrocyte basic protein
chr13_+_50070077 5.70 ENST00000378319.3
ENST00000426879.1
PHD finger protein 11
chr4_+_71588372 5.63 ENST00000536664.1
RUN and FYVE domain containing 3
chr9_-_100000957 5.57 ENST00000366109.2
ENST00000607322.1
RP11-498P14.5
chr10_+_95517616 5.56 ENST00000371418.4
leucine-rich, glioma inactivated 1
chr7_+_139529040 5.42 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
thromboxane A synthase 1 (platelet)
chr1_-_57045228 5.39 ENST00000371250.3
phosphatidic acid phosphatase type 2B
chr3_-_121379739 5.33 ENST00000428394.2
ENST00000314583.3
hematopoietic cell-specific Lyn substrate 1
chr4_-_99578789 5.26 ENST00000511651.1
ENST00000505184.1
tetraspanin 5
chr8_+_79428539 5.16 ENST00000352966.5
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr12_+_101988627 5.12 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
myosin binding protein C, slow type
chr12_+_51318513 5.11 ENST00000332160.4
methyltransferase like 7A
chr4_+_79567362 5.07 ENST00000512322.1
long intergenic non-protein coding RNA 1094
chr4_-_102268484 5.01 ENST00000394853.4
protein phosphatase 3, catalytic subunit, alpha isozyme
chr12_-_99038732 4.90 ENST00000393042.3
ENST00000420861.1
ENST00000299157.4
ENST00000342502.2
IKBKB interacting protein
chr22_-_17680472 4.86 ENST00000330232.4
cat eye syndrome chromosome region, candidate 1
chr7_+_139528952 4.85 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
thromboxane A synthase 1 (platelet)
chr20_+_9494987 4.85 ENST00000427562.2
ENST00000246070.2
lysosomal-associated membrane protein family, member 5
chr2_-_158345462 4.83 ENST00000439355.1
ENST00000540637.1
cytohesin 1 interacting protein
chr12_-_21487829 4.78 ENST00000445053.1
ENST00000452078.1
ENST00000458504.1
ENST00000422327.1
ENST00000421294.1
solute carrier organic anion transporter family, member 1A2
chr4_-_87028478 4.77 ENST00000515400.1
ENST00000395157.3
mitogen-activated protein kinase 10
chr5_+_161495038 4.71 ENST00000393933.4
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr4_-_102268628 4.71 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
protein phosphatase 3, catalytic subunit, alpha isozyme
chr15_+_58430368 4.70 ENST00000558772.1
ENST00000219919.4
aquaporin 9
chr1_-_150669604 4.69 ENST00000427665.1
ENST00000540514.1
golgi phosphoprotein 3-like
chr10_+_95517566 4.66 ENST00000542308.1
leucine-rich, glioma inactivated 1
chr4_-_176733897 4.51 ENST00000393658.2
glycoprotein M6A
chr4_+_79567314 4.49 ENST00000503539.1
ENST00000504675.1
long intergenic non-protein coding RNA 1094
chr14_-_21492113 4.42 ENST00000554094.1
NDRG family member 2
chr1_+_244214577 4.42 ENST00000358704.4
zinc finger and BTB domain containing 18
chrX_-_13835147 4.40 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chr13_-_67802549 4.39 ENST00000328454.5
ENST00000377865.2
protocadherin 9
chr12_+_59989791 4.38 ENST00000552432.1
solute carrier family 16 (monocarboxylate transporter), member 7
chr15_+_58430567 4.36 ENST00000536493.1
aquaporin 9
chr11_-_104480019 4.34 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
chrX_-_13835461 4.33 ENST00000316715.4
ENST00000356942.5
glycoprotein M6B
chr5_+_140220769 4.30 ENST00000531613.1
ENST00000378123.3
protocadherin alpha 8
chr19_+_45971246 4.16 ENST00000585836.1
ENST00000417353.2
ENST00000353609.3
ENST00000591858.1
ENST00000443841.2
ENST00000590335.1
FBJ murine osteosarcoma viral oncogene homolog B
chr19_-_40919271 4.12 ENST00000291825.7
ENST00000324001.7
periaxin
chr14_+_91580732 4.08 ENST00000519019.1
ENST00000523816.1
ENST00000517518.1
chromosome 14 open reading frame 159
chr11_+_63304273 4.04 ENST00000439013.2
ENST00000255688.3
retinoic acid receptor responder (tazarotene induced) 3
chr14_+_90863327 4.00 ENST00000356978.4
calmodulin 1 (phosphorylase kinase, delta)
chr14_+_91580777 3.99 ENST00000525393.2
ENST00000428926.2
ENST00000517362.1
chromosome 14 open reading frame 159
chr14_+_91580357 3.99 ENST00000298858.4
ENST00000521081.1
ENST00000520328.1
ENST00000256324.10
ENST00000524232.1
ENST00000522170.1
ENST00000519950.1
ENST00000523879.1
ENST00000521077.2
ENST00000518665.2
chromosome 14 open reading frame 159
chr2_-_145275228 3.94 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
zinc finger E-box binding homeobox 2
chr1_-_182360918 3.93 ENST00000339526.4
glutamate-ammonia ligase
chr7_+_121513143 3.93 ENST00000393386.2
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr11_+_5710919 3.90 ENST00000379965.3
ENST00000425490.1
tripartite motif containing 22
chr16_+_15528332 3.90 ENST00000566490.1
chromosome 16 open reading frame 45
chr11_+_108535849 3.90 ENST00000526794.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr14_+_91580708 3.89 ENST00000518868.1
chromosome 14 open reading frame 159
chr2_+_166150541 3.83 ENST00000283256.6
sodium channel, voltage-gated, type II, alpha subunit
chr14_-_21492251 3.82 ENST00000554398.1
NDRG family member 2
chr9_-_122131696 3.77 ENST00000373964.2
ENST00000265922.3
bone morphogenetic protein/retinoic acid inducible neural-specific 1
chr7_-_115670792 3.77 ENST00000265440.7
ENST00000393485.1
transcription factor EC
chr15_+_89182156 3.76 ENST00000379224.5
interferon stimulated exonuclease gene 20kDa
chr12_+_101988774 3.75 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
myosin binding protein C, slow type
chr1_+_111415757 3.74 ENST00000429072.2
ENST00000271324.5
CD53 molecule
chr15_+_89181974 3.70 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr14_+_91581011 3.64 ENST00000523894.1
ENST00000522322.1
ENST00000523771.1
chromosome 14 open reading frame 159
chr5_+_36608422 3.63 ENST00000381918.3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_+_173686303 3.63 ENST00000397087.3
Rap guanine nucleotide exchange factor (GEF) 4
chr6_+_89790490 3.63 ENST00000336032.3
proline-rich nuclear receptor coactivator 1
chr1_-_152332480 3.61 ENST00000388718.5
filaggrin family member 2
chr16_-_28621312 3.61 ENST00000314752.7
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr1_+_50571949 3.58 ENST00000357083.4
ELAV like neuron-specific RNA binding protein 4
chr8_-_120685608 3.56 ENST00000427067.2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr11_-_78052923 3.55 ENST00000340149.2
GRB2-associated binding protein 2
chr3_-_127541194 3.55 ENST00000453507.2
monoglyceride lipase
chr1_+_25664408 3.54 ENST00000374358.4
transmembrane protein 50A
chr11_-_5255861 3.52 ENST00000380299.3
hemoglobin, delta
chr3_-_10547333 3.47 ENST00000383800.4
ATPase, Ca++ transporting, plasma membrane 2
chr22_+_37678424 3.46 ENST00000248901.6
cytohesin 4
chr15_+_89182178 3.40 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr17_-_73844722 3.39 ENST00000586257.1
WW domain binding protein 2
chr18_+_77160282 3.27 ENST00000318065.5
ENST00000545796.1
ENST00000592223.1
ENST00000329101.4
ENST00000586434.1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr8_-_18871159 3.26 ENST00000327040.8
ENST00000440756.2
pleckstrin and Sec7 domain containing 3
chr17_+_4613918 3.26 ENST00000574954.1
ENST00000346341.2
ENST00000572457.1
ENST00000381488.6
ENST00000412477.3
ENST00000571428.1
ENST00000575877.1
arrestin, beta 2
chr2_-_85839146 3.24 ENST00000306336.5
ENST00000409734.3
chromosome 2 open reading frame 68
chr18_-_53253323 3.21 ENST00000540999.1
ENST00000563888.2
transcription factor 4
chr4_+_165675269 3.19 ENST00000507311.1
RP11-294O2.2
chr2_+_233497931 3.17 ENST00000264059.3
EF-hand domain family, member D1
chr16_-_4852915 3.14 ENST00000322048.7
rogdi homolog (Drosophila)
chr5_-_127674883 3.14 ENST00000507835.1
fibrillin 2
chr1_-_160681593 3.10 ENST00000368045.3
ENST00000368046.3
CD48 molecule
chr6_+_150690133 3.09 ENST00000392255.3
ENST00000500320.3
iodotyrosine deiodinase
chr1_-_182360498 3.08 ENST00000417584.2
glutamate-ammonia ligase
chr3_-_10547192 3.04 ENST00000360273.2
ENST00000343816.4
ATPase, Ca++ transporting, plasma membrane 2
chr6_+_101846664 3.03 ENST00000421544.1
ENST00000413795.1
ENST00000369138.1
ENST00000358361.3
glutamate receptor, ionotropic, kainate 2
chrM_+_4431 3.03 ENST00000361453.3
mitochondrially encoded NADH dehydrogenase 2
chr18_-_53089723 3.02 ENST00000561992.1
ENST00000562512.2
transcription factor 4
chr1_-_9811600 3.02 ENST00000435891.1
calsyntenin 1
chr18_-_53253112 3.00 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
transcription factor 4
chr1_-_177134024 2.99 ENST00000367654.3
astrotactin 1
chr1_+_226411319 2.97 ENST00000542034.1
ENST00000366810.5
Mix paired-like homeobox
chr2_-_211341411 2.95 ENST00000233714.4
ENST00000443314.1
ENST00000441020.3
ENST00000450366.2
ENST00000431941.2
LanC lantibiotic synthetase component C-like 1 (bacterial)
chr8_+_85095497 2.95 ENST00000522455.1
ENST00000521695.1
RALY RNA binding protein-like
chr19_+_782755 2.95 ENST00000606242.1
ENST00000586061.1
AC006273.5
chr13_+_113633620 2.93 ENST00000421756.1
ENST00000375601.3
MCF.2 cell line derived transforming sequence-like
chr3_+_115342159 2.91 ENST00000305124.6
growth associated protein 43
chr1_-_226926864 2.90 ENST00000429204.1
ENST00000366784.1
inositol-trisphosphate 3-kinase B
chr4_-_90756769 2.89 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
synuclein, alpha (non A4 component of amyloid precursor)
chr11_+_46368956 2.87 ENST00000543978.1
diacylglycerol kinase, zeta
chr4_-_102267953 2.87 ENST00000523694.2
ENST00000507176.1
protein phosphatase 3, catalytic subunit, alpha isozyme
chr2_+_29204161 2.86 ENST00000379558.4
ENST00000403861.2
family with sequence similarity 179, member A
chr11_+_65657875 2.85 ENST00000312579.2
coiled-coil domain containing 85B
chr1_+_202995611 2.83 ENST00000367240.2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr11_-_107582775 2.81 ENST00000305991.2
sarcolipin
chr16_-_28621298 2.79 ENST00000566189.1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr11_-_59950622 2.78 ENST00000323961.3
ENST00000412309.2
membrane-spanning 4-domains, subfamily A, member 6A
chr1_-_182361327 2.76 ENST00000331872.6
ENST00000311223.5
glutamate-ammonia ligase
chr14_-_94854926 2.72 ENST00000402629.1
ENST00000556091.1
ENST00000554720.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr15_+_78730622 2.72 ENST00000560440.1
iron-responsive element binding protein 2
chr3_+_158991025 2.71 ENST00000337808.6
IQCJ-SCHIP1 readthrough
chr8_+_85095553 2.70 ENST00000521268.1
RALY RNA binding protein-like
chr1_+_2005425 2.68 ENST00000461106.2
protein kinase C, zeta
chr1_-_170043709 2.67 ENST00000367767.1
ENST00000361580.2
ENST00000538366.1
kinesin-associated protein 3
chr1_+_198608146 2.65 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
protein tyrosine phosphatase, receptor type, C
chr18_-_53177984 2.61 ENST00000543082.1
transcription factor 4
chr1_-_15911510 2.57 ENST00000375826.3
agmatine ureohydrolase (agmatinase)
chr4_-_99578776 2.54 ENST00000515287.1
tetraspanin 5
chr3_+_158787041 2.53 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1 readthrough
chr19_+_8483272 2.52 ENST00000602117.1
membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
chr8_-_120651020 2.51 ENST00000522826.1
ENST00000520066.1
ENST00000259486.6
ENST00000075322.6
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr3_-_49131788 2.51 ENST00000395443.2
ENST00000411682.1
glutamine-rich 1
chr1_+_150122034 2.48 ENST00000025469.6
ENST00000369124.4
pleckstrin homology domain containing, family O member 1
chr12_-_15114603 2.47 ENST00000228945.4
Rho GDP dissociation inhibitor (GDI) beta
chr11_-_790060 2.45 ENST00000330106.4
cell cycle exit and neuronal differentiation 1
chr7_+_80231466 2.45 ENST00000309881.7
ENST00000534394.1
CD36 molecule (thrombospondin receptor)
chr18_+_32556892 2.43 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
microtubule-associated protein, RP/EB family, member 2
chr17_-_73851285 2.42 ENST00000589642.1
ENST00000593002.1
ENST00000590221.1
ENST00000344296.4
ENST00000587374.1
ENST00000585462.1
ENST00000433525.2
ENST00000254806.3
WW domain binding protein 2
chr4_-_74486347 2.42 ENST00000342081.3
Ras association (RalGDS/AF-6) domain family member 6
chr16_+_2588012 2.41 ENST00000354836.5
ENST00000389224.3
3-phosphoinositide dependent protein kinase-1
chrX_-_70331298 2.41 ENST00000456850.2
ENST00000473378.1
ENST00000487883.1
ENST00000374202.2
interleukin 2 receptor, gamma
chr13_-_33002151 2.40 ENST00000495479.1
ENST00000343281.4
ENST00000464470.1
ENST00000380139.4
ENST00000380133.2
NEDD4 binding protein 2-like 1
chr4_-_153274078 2.40 ENST00000263981.5
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr1_+_229440129 2.39 ENST00000366688.3
S-phase response (cyclin related)
chrX_+_9431324 2.39 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
transducin (beta)-like 1X-linked
chr7_+_151771377 2.37 ENST00000434507.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr19_+_3880581 2.36 ENST00000450849.2
ENST00000301260.6
ENST00000398448.3
ataxia, cerebellar, Cayman type
chr1_+_66797687 2.35 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
phosphodiesterase 4B, cAMP-specific
chr12_+_54892550 2.34 ENST00000545638.2
NCK-associated protein 1-like
chr12_-_51718436 2.34 ENST00000544402.1
bridging integrator 2
chr7_+_29237354 2.33 ENST00000546235.1
chimerin 2
chr2_-_224467093 2.32 ENST00000305409.2
secretogranin II
chr1_-_177133818 2.31 ENST00000424564.2
ENST00000361833.2
astrotactin 1
chr6_+_31553978 2.30 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
leukocyte specific transcript 1
chr8_+_85618155 2.29 ENST00000523850.1
ENST00000521376.1
RALY RNA binding protein-like
chr2_+_163175394 2.26 ENST00000446271.1
ENST00000429691.2
grancalcin, EF-hand calcium binding protein
chr12_-_26278030 2.26 ENST00000242728.4
basic helix-loop-helix family, member e41
chr11_+_108093559 2.25 ENST00000278616.4
ataxia telangiectasia mutated
chr19_-_37701386 2.25 ENST00000527838.1
ENST00000591492.1
ENST00000532828.2
zinc finger protein 585B
chr4_-_90759440 2.25 ENST00000336904.3
synuclein, alpha (non A4 component of amyloid precursor)
chr7_+_80275752 2.25 ENST00000419819.2
CD36 molecule (thrombospondin receptor)
chr10_+_111967345 2.24 ENST00000332674.5
ENST00000453116.1
MAX interactor 1, dimerization protein
chr7_+_80267973 2.24 ENST00000394788.3
ENST00000447544.2
CD36 molecule (thrombospondin receptor)
chr11_+_27076764 2.22 ENST00000525090.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXD3_FOXI1_FOXF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 24.2 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
4.2 12.6 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
3.8 15.1 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
3.6 10.9 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
3.3 10.0 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
3.3 9.9 GO:1904647 response to rotenone(GO:1904647)
3.0 9.0 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
2.4 9.6 GO:0006542 glutamine biosynthetic process(GO:0006542)
2.4 2.4 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
2.2 11.0 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
2.1 38.4 GO:0007021 tubulin complex assembly(GO:0007021)
1.8 9.1 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) urea transmembrane transport(GO:0071918) purine nucleobase transmembrane transport(GO:1904823)
1.8 12.6 GO:2000334 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
1.6 16.3 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
1.6 15.7 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.5 10.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
1.2 1.2 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
1.1 18.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
1.1 3.4 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
1.1 5.4 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
1.1 4.3 GO:0071461 cellular response to redox state(GO:0071461)
1.0 2.0 GO:0071168 protein localization to chromatin(GO:0071168)
1.0 2.0 GO:0045900 negative regulation of translational elongation(GO:0045900)
1.0 3.9 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
1.0 7.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.9 2.8 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.9 6.5 GO:0032596 protein transport within lipid bilayer(GO:0032594) protein transport into membrane raft(GO:0032596)
0.9 7.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.9 5.5 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.9 2.7 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.9 4.4 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.9 2.6 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.8 11.9 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.8 0.8 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.8 5.8 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.8 10.6 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.8 0.8 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.8 7.7 GO:0015939 pantothenate metabolic process(GO:0015939)
0.8 2.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.8 11.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.8 2.3 GO:1904882 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.7 3.7 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.7 1.5 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.7 2.9 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.7 9.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.7 5.3 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.7 5.3 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.7 5.3 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.6 3.2 GO:0032455 nerve growth factor processing(GO:0032455)
0.6 2.6 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.6 1.9 GO:0032782 bile acid secretion(GO:0032782)
0.6 1.8 GO:0021764 amygdala development(GO:0021764)
0.6 2.4 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.6 10.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.6 11.4 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.6 3.0 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.6 4.7 GO:0071352 cellular response to interleukin-2(GO:0071352)
0.6 2.3 GO:0072402 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.6 18.6 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.6 1.7 GO:1901189 arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.6 4.0 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.6 23.2 GO:0006536 glutamate metabolic process(GO:0006536)
0.6 1.7 GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.6 3.4 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.6 1.1 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.6 3.9 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.5 8.2 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.5 8.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.5 2.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.5 1.0 GO:0007632 visual behavior(GO:0007632)
0.5 10.4 GO:0071420 cellular response to histamine(GO:0071420)
0.5 2.0 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.5 1.5 GO:0001694 histamine biosynthetic process(GO:0001694)
0.5 1.5 GO:0019417 sulfur oxidation(GO:0019417)
0.5 21.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.5 9.4 GO:0006068 ethanol catabolic process(GO:0006068)
0.5 2.4 GO:0021699 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.5 2.0 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.5 15.6 GO:0016601 Rac protein signal transduction(GO:0016601)
0.5 2.9 GO:0016198 axon choice point recognition(GO:0016198)
0.5 1.4 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.4 7.6 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.4 2.7 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-10 secretion(GO:2001181)
0.4 0.4 GO:0071347 cellular response to interleukin-1(GO:0071347)
0.4 6.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.4 1.2 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.4 4.3 GO:0006570 tyrosine metabolic process(GO:0006570)
0.4 1.2 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.4 1.1 GO:0021542 dentate gyrus development(GO:0021542)
0.4 1.1 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.4 6.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.4 3.9 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.3 5.9 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.3 15.5 GO:0042417 dopamine metabolic process(GO:0042417)
0.3 3.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.3 5.3 GO:0051639 actin filament network formation(GO:0051639)
0.3 1.3 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.3 1.3 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.3 2.6 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.3 5.0 GO:0007614 short-term memory(GO:0007614)
0.3 0.9 GO:0072709 cellular response to sorbitol(GO:0072709)
0.3 3.7 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.3 0.9 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.3 2.1 GO:0048241 epinephrine transport(GO:0048241)
0.3 2.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.3 1.8 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.3 1.2 GO:0006808 regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740) negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.3 0.9 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.3 1.5 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.3 2.1 GO:0031647 regulation of protein stability(GO:0031647)
0.3 2.4 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.3 0.9 GO:0043315 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.3 0.8 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.3 1.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.3 1.4 GO:0048388 endosomal lumen acidification(GO:0048388)
0.3 2.5 GO:0051451 myoblast migration(GO:0051451)
0.3 2.7 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.3 2.7 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.3 1.9 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.3 2.2 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.3 8.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.3 4.9 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.3 1.0 GO:0048749 compound eye development(GO:0048749)
0.3 1.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.3 0.3 GO:0006779 porphyrin-containing compound metabolic process(GO:0006778) porphyrin-containing compound biosynthetic process(GO:0006779)
0.2 15.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.2 6.6 GO:0048665 neuron fate specification(GO:0048665)
0.2 3.5 GO:0015671 oxygen transport(GO:0015671)
0.2 1.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.2 1.6 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.2 0.2 GO:2000143 negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.2 1.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.2 1.8 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 0.7 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.2 1.5 GO:0021513 spinal cord dorsal/ventral patterning(GO:0021513)
0.2 1.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.2 1.1 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.2 1.5 GO:0042426 choline catabolic process(GO:0042426)
0.2 0.9 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.2 3.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 0.8 GO:0007525 somatic muscle development(GO:0007525)
0.2 1.2 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.2 4.1 GO:0035855 megakaryocyte development(GO:0035855)
0.2 0.8 GO:0046502 uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.2 0.6 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.2 0.6 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.2 3.3 GO:0051412 response to corticosterone(GO:0051412)
0.2 2.3 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.2 1.4 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.2 0.4 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.2 4.0 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 0.6 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.2 5.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.2 0.7 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.2 3.7 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.2 6.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.2 1.1 GO:0035881 amacrine cell differentiation(GO:0035881)
0.2 0.5 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.2 0.9 GO:0042713 sperm ejaculation(GO:0042713)
0.2 1.4 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.2 0.7 GO:2001176 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.2 1.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 0.7 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.2 0.4 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.2 2.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.2 0.7 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.2 3.1 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.2 0.7 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.2 0.5 GO:0051409 response to nitrosative stress(GO:0051409)
0.2 2.0 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.2 0.7 GO:0032571 response to vitamin K(GO:0032571)
0.2 0.7 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.2 1.6 GO:0046078 dUMP metabolic process(GO:0046078)
0.2 3.5 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.2 1.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 0.5 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.2 1.3 GO:0042908 xenobiotic transport(GO:0042908)
0.2 0.2 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.2 2.3 GO:0097320 membrane tubulation(GO:0097320)
0.2 0.8 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.2 2.5 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.2 0.9 GO:0018095 protein polyglutamylation(GO:0018095)
0.2 4.7 GO:0008045 motor neuron axon guidance(GO:0008045)
0.2 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2 2.3 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.1 0.4 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 20.4 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
0.1 1.1 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.1 0.4 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 1.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 1.4 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.1 0.3 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.7 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.1 1.4 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 1.0 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.1 GO:0035425 autocrine signaling(GO:0035425)
0.1 1.3 GO:0051026 chiasma assembly(GO:0051026)
0.1 1.4 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.1 3.7 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.1 0.8 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 0.8 GO:1904251 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.1 0.7 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 1.4 GO:0021794 thalamus development(GO:0021794)
0.1 1.2 GO:0050709 negative regulation of protein secretion(GO:0050709)
0.1 3.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.8 GO:0006196 AMP catabolic process(GO:0006196)
0.1 3.6 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.1 1.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.9 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.1 0.7 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.1 0.7 GO:0044211 CTP salvage(GO:0044211)
0.1 17.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 2.5 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.1 0.5 GO:0097368 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.1 3.6 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.1 1.4 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.1 0.9 GO:0035690 cellular response to drug(GO:0035690)
0.1 0.5 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 1.4 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.3 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1 0.4 GO:0070141 creatinine metabolic process(GO:0046449) response to UV-A(GO:0070141) cellular response to UV-A(GO:0071492)
0.1 1.6 GO:0036010 protein localization to endosome(GO:0036010)
0.1 0.3 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.7 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.1 0.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 1.1 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.1 1.4 GO:0008038 neuron recognition(GO:0008038)
0.1 0.3 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.9 GO:0007379 segment specification(GO:0007379)
0.1 0.4 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 1.4 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.8 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.3 GO:0052055 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.1 0.5 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.1 GO:1903487 regulation of lactation(GO:1903487)
0.1 0.6 GO:0009597 detection of virus(GO:0009597)
0.1 0.5 GO:0001554 luteolysis(GO:0001554)
0.1 0.9 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 2.7 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.1 1.2 GO:0060346 bone trabecula formation(GO:0060346)
0.1 1.2 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 0.2 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.1 1.9 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.4 GO:1901374 acetate ester transport(GO:1901374)
0.1 1.9 GO:0042462 eye photoreceptor cell differentiation(GO:0001754) eye photoreceptor cell development(GO:0042462)
0.1 3.6 GO:0003407 neural retina development(GO:0003407)
0.1 3.7 GO:0010165 response to X-ray(GO:0010165)
0.1 0.8 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.1 0.2 GO:0071288 cellular response to mercury ion(GO:0071288)
0.1 1.7 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 0.7 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.9 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.3 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 2.4 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.1 1.4 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.1 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 1.1 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 0.5 GO:0016559 peroxisome fission(GO:0016559)
0.1 0.3 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.1 0.7 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.2 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.1 0.8 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 2.3 GO:0014047 glutamate secretion(GO:0014047)
0.1 1.6 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 3.1 GO:0019228 neuronal action potential(GO:0019228)
0.1 0.8 GO:0048820 hair follicle maturation(GO:0048820)
0.1 1.0 GO:0035878 nail development(GO:0035878)
0.1 0.9 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 2.0 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 0.3 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 0.8 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1 1.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.8 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.1 0.5 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.5 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.1 0.4 GO:0071907 determination of pancreatic left/right asymmetry(GO:0035469) determination of digestive tract left/right asymmetry(GO:0071907) determination of liver left/right asymmetry(GO:0071910)
0.1 0.5 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.1 0.5 GO:0008343 adult feeding behavior(GO:0008343)
0.1 0.3 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.1 1.7 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 1.1 GO:0033141 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 0.9 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 0.4 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015) inositol lipid-mediated signaling(GO:0048017)
0.1 0.2 GO:1901993 meiotic cell cycle phase transition(GO:0044771) establishment of meiotic spindle localization(GO:0051295) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 1.8 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.1 0.4 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 1.9 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 0.5 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 0.3 GO:2000345 regulation of hepatocyte proliferation(GO:2000345)
0.1 2.6 GO:0070206 protein trimerization(GO:0070206)
0.1 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.5 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.1 1.0 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.6 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.1 0.3 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 0.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.6 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.1 0.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.4 GO:0032790 ribosome disassembly(GO:0032790)
0.1 0.4 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.1 2.8 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 0.7 GO:0033561 regulation of water loss via skin(GO:0033561) establishment of skin barrier(GO:0061436)
0.1 3.2 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.1 1.5 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 0.5 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 1.2 GO:0090314 positive regulation of protein targeting to membrane(GO:0090314)
0.1 0.2 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 1.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.1 0.2 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 1.0 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.1 0.3 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.4 GO:1903392 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.0 0.5 GO:0001696 gastric acid secretion(GO:0001696)
0.0 0.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 11.6 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 1.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.2 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.2 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.1 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 1.0 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 1.5 GO:0032259 methylation(GO:0032259)
0.0 0.5 GO:0014029 neural crest formation(GO:0014029)
0.0 0.0 GO:0050955 thermoception(GO:0050955)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 2.7 GO:0006826 iron ion transport(GO:0006826)
0.0 0.1 GO:0036071 N-glycan fucosylation(GO:0036071)
0.0 1.0 GO:0001701 in utero embryonic development(GO:0001701)
0.0 1.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 1.6 GO:0010107 potassium ion import(GO:0010107)
0.0 0.5 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 2.9 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 1.8 GO:0021510 spinal cord development(GO:0021510)
0.0 0.2 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.6 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.9 GO:0060964 regulation of gene silencing by miRNA(GO:0060964)
0.0 0.8 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.7 GO:0030155 regulation of cell adhesion(GO:0030155)
0.0 0.9 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 1.1 GO:1901998 toxin transport(GO:1901998)
0.0 0.5 GO:0035303 regulation of dephosphorylation(GO:0035303)
0.0 0.1 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.4 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.3 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.3 GO:0032607 interferon-alpha production(GO:0032607)
0.0 0.5 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.7 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.0 0.1 GO:1901991 negative regulation of cell cycle phase transition(GO:1901988) negative regulation of mitotic cell cycle phase transition(GO:1901991)
0.0 0.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 0.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.1 GO:1901524 regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525)
0.0 0.0 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 1.2 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.2 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 2.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.0 GO:0031999 negative regulation of fatty acid beta-oxidation(GO:0031999)
0.0 0.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 1.5 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.5 GO:0061024 membrane organization(GO:0061024)
0.0 1.2 GO:0008366 ensheathment of neurons(GO:0007272) axon ensheathment(GO:0008366)
0.0 0.2 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.6 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.2 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.5 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.1 GO:0070314 G1 to G0 transition(GO:0070314) G1 to G0 transition involved in cell differentiation(GO:0070315) negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.0 0.4 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.5 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.9 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.3 GO:0032414 positive regulation of ion transmembrane transporter activity(GO:0032414)
0.0 0.8 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 18.9 GO:0098843 postsynaptic endocytic zone(GO:0098843)
3.5 24.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
2.4 38.4 GO:0097512 cardiac myofibril(GO:0097512)
2.0 10.0 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
1.4 12.6 GO:0005955 calcineurin complex(GO:0005955)
1.3 3.9 GO:0072534 perineuronal net(GO:0072534)
1.3 15.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
1.3 16.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
1.1 7.8 GO:0032584 growth cone membrane(GO:0032584)
0.9 3.7 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.9 18.5 GO:0001891 phagocytic cup(GO:0001891)
0.9 3.5 GO:1990075 periciliary membrane compartment(GO:1990075)
0.9 2.6 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.8 2.5 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.8 3.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.7 12.7 GO:0033270 paranode region of axon(GO:0033270)
0.7 3.4 GO:0001652 granular component(GO:0001652)
0.6 19.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.6 2.3 GO:0043293 apoptosome(GO:0043293)
0.6 15.6 GO:0071437 invadopodium(GO:0071437)
0.5 8.5 GO:0097386 glial cell projection(GO:0097386)
0.5 2.0 GO:0070695 FHF complex(GO:0070695)
0.4 1.3 GO:0036398 TCR signalosome(GO:0036398)
0.4 17.8 GO:0032590 dendrite membrane(GO:0032590)
0.4 2.0 GO:0097179 protease inhibitor complex(GO:0097179)
0.3 9.1 GO:0032982 myosin filament(GO:0032982)
0.3 1.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.3 1.0 GO:0031251 PAN complex(GO:0031251)
0.3 2.7 GO:0045179 apical cortex(GO:0045179)
0.3 1.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.3 10.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 1.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.3 1.1 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.3 1.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.3 3.5 GO:0005833 hemoglobin complex(GO:0005833)
0.2 1.6 GO:0044326 dendritic spine neck(GO:0044326)
0.2 9.9 GO:1904115 axon cytoplasm(GO:1904115)
0.2 24.2 GO:0016234 inclusion body(GO:0016234)
0.2 4.3 GO:0044295 axonal growth cone(GO:0044295)
0.2 1.7 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.2 2.0 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 2.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 2.3 GO:0031209 SCAR complex(GO:0031209)
0.2 2.6 GO:0031045 dense core granule(GO:0031045)
0.2 0.8 GO:0036128 CatSper complex(GO:0036128)
0.2 4.0 GO:0031264 death-inducing signaling complex(GO:0031264)
0.2 1.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.2 1.3 GO:0000322 storage vacuole(GO:0000322)
0.2 10.1 GO:0015030 Cajal body(GO:0015030)
0.2 2.0 GO:0043679 axon terminus(GO:0043679)
0.2 0.8 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.4 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.1 5.7 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 1.4 GO:0045180 basal cortex(GO:0045180)
0.1 2.0 GO:0097440 apical dendrite(GO:0097440)
0.1 0.3 GO:0098576 lumenal side of membrane(GO:0098576)
0.1 17.2 GO:0043204 perikaryon(GO:0043204)
0.1 2.9 GO:0000242 pericentriolar material(GO:0000242)
0.1 1.7 GO:0016600 flotillin complex(GO:0016600)
0.1 1.0 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.7 GO:0034464 BBSome(GO:0034464)
0.1 6.6 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.5 GO:0000801 central element(GO:0000801)
0.1 17.3 GO:0043197 dendritic spine(GO:0043197)
0.1 2.0 GO:0010369 chromocenter(GO:0010369)
0.1 1.3 GO:0097433 dense body(GO:0097433)
0.1 1.9 GO:0031528 microvillus membrane(GO:0031528)
0.1 1.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 4.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 1.1 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 4.5 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.6 GO:0002177 manchette(GO:0002177)
0.1 0.6 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.7 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 8.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 1.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.2 GO:0070578 RISC-loading complex(GO:0070578)
0.1 7.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 2.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 1.0 GO:0005657 replication fork(GO:0005657)
0.1 6.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 3.5 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.1 0.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 1.2 GO:0032300 mismatch repair complex(GO:0032300)
0.1 8.8 GO:0030426 growth cone(GO:0030426)
0.1 0.4 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 0.5 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 0.7 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 2.8 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.1 0.5 GO:0032437 cuticular plate(GO:0032437)
0.1 0.6 GO:0016013 syntrophin complex(GO:0016013)
0.1 1.6 GO:0071564 npBAF complex(GO:0071564)
0.1 0.4 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 2.8 GO:0001772 immunological synapse(GO:0001772)
0.1 2.7 GO:0000776 kinetochore(GO:0000776)
0.1 1.0 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 1.8 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 0.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.5 GO:0097486 multivesicular body lumen(GO:0097486)
0.1 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.6 GO:0090544 BAF-type complex(GO:0090544)
0.1 10.4 GO:0043025 neuronal cell body(GO:0043025)
0.0 1.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.9 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 1.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 3.6 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 2.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.3 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 29.1 GO:0045202 synapse(GO:0045202)
0.0 7.1 GO:0032993 protein-DNA complex(GO:0032993)
0.0 8.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.7 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.4 GO:0000243 commitment complex(GO:0000243)
0.0 0.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.6 GO:0055037 recycling endosome(GO:0055037)
0.0 2.0 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 4.0 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 4.1 GO:0005769 early endosome(GO:0005769)
0.0 0.4 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.4 GO:0030424 axon(GO:0030424)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.9 GO:0042641 actomyosin(GO:0042641)
0.0 0.3 GO:0031526 brush border membrane(GO:0031526)
0.0 1.4 GO:0005929 cilium(GO:0005929)
0.0 29.2 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 14.3 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.2 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 0.7 GO:0005844 polysome(GO:0005844)
0.0 0.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 2.4 GO:0043005 neuron projection(GO:0043005)
0.0 27.4 GO:0016021 integral component of membrane(GO:0016021)
0.0 1.3 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 0.1 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 19.6 GO:0047820 D-glutamate cyclase activity(GO:0047820)
3.6 10.9 GO:0008859 exoribonuclease II activity(GO:0008859)
3.4 10.3 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
3.0 24.2 GO:0050816 phosphothreonine binding(GO:0050816)
2.4 7.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
2.4 9.6 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
2.3 9.1 GO:0015254 glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
2.1 10.5 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
2.1 12.6 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
2.0 10.0 GO:0030348 syntaxin-3 binding(GO:0030348)
2.0 7.8 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
1.9 24.5 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.8 5.4 GO:0031859 platelet activating factor receptor binding(GO:0031859)
1.8 5.3 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
1.7 24.4 GO:1903136 cuprous ion binding(GO:1903136)
1.6 18.9 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
1.5 7.7 GO:0017159 pantetheine hydrolase activity(GO:0017159)
1.5 6.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
1.4 14.0 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
1.3 4.0 GO:0004913 interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917)
1.3 5.3 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
1.3 7.7 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.2 38.3 GO:0005212 structural constituent of eye lens(GO:0005212)
1.2 10.8 GO:0032051 clathrin light chain binding(GO:0032051)
1.2 8.3 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
1.0 11.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.9 2.7 GO:0030350 iron-responsive element binding(GO:0030350)
0.9 2.6 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.8 2.4 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.8 10.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.8 2.3 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.7 4.3 GO:0004447 iodide peroxidase activity(GO:0004447)
0.7 0.7 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.7 15.1 GO:0035198 miRNA binding(GO:0035198)
0.7 17.9 GO:0005521 lamin binding(GO:0005521)
0.6 2.6 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.6 9.0 GO:0031432 titin binding(GO:0031432)
0.6 1.9 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.6 8.8 GO:0030957 Tat protein binding(GO:0030957)
0.6 3.0 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.6 7.6 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.6 2.8 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.5 1.6 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.5 3.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.5 1.6 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.5 12.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.5 5.5 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.5 2.9 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.5 1.8 GO:1904493 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
0.4 3.0 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.4 4.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.4 1.3 GO:0032427 GBD domain binding(GO:0032427)
0.4 1.7 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.4 3.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.4 1.6 GO:0016841 ammonia-lyase activity(GO:0016841)
0.4 1.9 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.4 1.5 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.4 1.9 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.4 2.3 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.4 3.3 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.4 2.9 GO:0016778 diphosphotransferase activity(GO:0016778)
0.4 1.4 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.3 3.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.3 0.7 GO:0034046 poly(G) binding(GO:0034046)
0.3 5.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.3 4.7 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.3 3.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.3 1.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.3 1.8 GO:0042610 CD8 receptor binding(GO:0042610)
0.3 14.9 GO:0019894 kinesin binding(GO:0019894)
0.3 2.0 GO:0001515 opioid peptide activity(GO:0001515)
0.3 2.9 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.3 2.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.3 1.6 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.3 3.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.3 6.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.3 2.3 GO:0043426 MRF binding(GO:0043426)
0.2 1.7 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.2 0.2 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.2 0.7 GO:0046965 retinoid X receptor binding(GO:0046965)
0.2 1.2 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.2 1.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 0.7 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 5.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 1.1 GO:0099583 postsynaptic neurotransmitter receptor activity(GO:0098960) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.2 0.9 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 37.3 GO:0017124 SH3 domain binding(GO:0017124)
0.2 4.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.2 0.8 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2 4.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.2 3.7 GO:0004622 lysophospholipase activity(GO:0004622)
0.2 1.7 GO:0000150 recombinase activity(GO:0000150)
0.2 0.9 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.2 2.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 3.0 GO:0070513 death domain binding(GO:0070513)
0.2 2.3 GO:0043274 phospholipase binding(GO:0043274)
0.2 0.9 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.2 1.9 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.2 3.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2 4.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 1.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.2 0.7 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.2 1.9 GO:0045159 myosin II binding(GO:0045159)
0.2 0.5 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.2 0.9 GO:0098821 BMP receptor activity(GO:0098821)
0.2 0.9 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2 2.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 1.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.4 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.1 1.1 GO:1901612 cardiolipin binding(GO:1901612)
0.1 2.0 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 7.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 1.0 GO:0000403 Y-form DNA binding(GO:0000403)
0.1 1.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 1.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 3.0 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 0.9 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.9 GO:0008142 oxysterol binding(GO:0008142)
0.1 5.2 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.6 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.5 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 6.4 GO:0015485 cholesterol binding(GO:0015485) sterol binding(GO:0032934)
0.1 0.4 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 3.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 3.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 3.2 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 0.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 2.0 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 1.4 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 2.9 GO:0097200 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.5 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 3.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.3 GO:0035276 ethanol binding(GO:0035276)
0.1 0.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.3 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 2.5 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.5 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.7 GO:0004849 uridine kinase activity(GO:0004849)
0.1 1.1 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.3 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.3 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.1 0.8 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 0.9 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.9 GO:0003777 microtubule motor activity(GO:0003777)
0.1 7.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.5 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 1.0 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.3 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.9 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 2.5 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.8 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.5 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 0.9 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 1.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 1.4 GO:0005109 frizzled binding(GO:0005109)
0.1 1.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 1.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 1.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.5 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.2 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.1 0.5 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.1 1.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 8.9 GO:0005262 calcium channel activity(GO:0005262)
0.1 1.7 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.1 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 1.0 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 1.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.5 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 1.9 GO:0030552 cAMP binding(GO:0030552)
0.1 1.5 GO:0071949 FAD binding(GO:0071949)
0.1 0.5 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.1 0.4 GO:0019213 deacetylase activity(GO:0019213)
0.1 0.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.8 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 4.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 1.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 1.0 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 1.4 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.1 1.0 GO:0019864 IgG binding(GO:0019864)
0.1 0.6 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.1 0.8 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.7 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 6.4 GO:0044325 ion channel binding(GO:0044325)
0.1 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 12.8 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.4 GO:0005372 water transmembrane transporter activity(GO:0005372) water channel activity(GO:0015250)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 1.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.1 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 1.0 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.5 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 1.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.9 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.0 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.3 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 3.1 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.3 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 2.0 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.2 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 9.2 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.3 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.2 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.2 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0 0.6 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 1.4 GO:0016782 transferase activity, transferring sulfur-containing groups(GO:0016782)
0.0 2.4 GO:0002020 protease binding(GO:0002020)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.6 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467) fatty acid ligase activity(GO:0015645)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.9 GO:0043022 ribosome binding(GO:0043022)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0036317 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.0 0.1 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 4.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 1.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.0 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.5 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.5 GO:0002039 p53 binding(GO:0002039)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.6 32.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.4 21.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.4 22.8 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.4 21.8 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.4 28.4 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.3 2.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.3 14.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.2 4.0 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.2 2.7 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.2 10.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 7.7 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.2 6.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.2 2.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 4.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 2.2 PID CD40 PATHWAY CD40/CD40L signaling
0.1 8.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 1.7 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 4.1 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 7.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 4.6 PID IL1 PATHWAY IL1-mediated signaling events
0.1 3.7 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 3.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 12.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.3 PID BCR 5PATHWAY BCR signaling pathway
0.1 0.9 PID ALK1 PATHWAY ALK1 signaling events
0.1 2.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 5.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.1 1.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.5 PID EPO PATHWAY EPO signaling pathway
0.0 0.9 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.9 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.7 PID FGF PATHWAY FGF signaling pathway
0.0 1.6 PID ATR PATHWAY ATR signaling pathway
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.8 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 1.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.5 PID P73PATHWAY p73 transcription factor network
0.0 0.4 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 18.9 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.7 39.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.7 6.1 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.7 9.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.6 11.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.6 11.0 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.6 19.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.5 7.7 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.4 10.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.4 18.8 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.4 8.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.4 11.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.4 5.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.4 8.1 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.3 9.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.3 10.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.3 9.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.3 11.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 9.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 3.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.3 2.6 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.2 6.7 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 3.0 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.2 4.8 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 4.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 3.9 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.2 2.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.2 3.0 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 10.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.2 6.9 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.2 1.3 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.2 0.6 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.2 3.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2 14.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.2 13.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 4.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 5.4 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 3.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.7 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 3.6 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1 4.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 2.0 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 0.9 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 2.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 4.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 2.0 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 11.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.6 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 0.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 4.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 15.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 9.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 3.1 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 2.5 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 0.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 4.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 3.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.9 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.2 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.1 REACTOME SIGNALLING BY NGF Genes involved in Signalling by NGF
0.0 1.2 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.1 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.7 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 2.3 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.8 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.5 REACTOME SIGNALING BY FGFR MUTANTS Genes involved in Signaling by FGFR mutants
0.0 0.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol