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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
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Results for GAUAUGU
Z-value: 0.64
Motif logo
miRNA associated with seed GAUAUGU
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_+_24612935 Show fit | 1.35 |
ENST00000222644.5
|
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
|
| chr5_+_61602055 Show fit | 1.26 |
ENST00000381103.2
|
kinesin heavy chain member 2A |
|
| chr3_-_160283348 Show fit | 0.99 |
ENST00000334256.4
|
karyopherin alpha 4 (importin alpha 3) |
|
| chr2_+_114647504 Show fit | 0.98 |
ENST00000263238.2
|
ARP3 actin-related protein 3 homolog (yeast) |
|
| chr19_-_1652575 Show fit | 0.95 |
ENST00000587235.1
ENST00000262965.5 |
transcription factor 3 |
|
| chr8_+_61591337 Show fit | 0.95 |
ENST00000423902.2
|
chromodomain helicase DNA binding protein 7 |
|
| chr2_+_228336849 Show fit | 0.74 |
ENST00000409979.2
ENST00000310078.8 |
ArfGAP with FG repeats 1 |
|
| chr12_-_118797475 Show fit | 0.69 |
ENST00000541786.1
ENST00000419821.2 ENST00000541878.1 |
TAO kinase 3 |
|
| chr8_-_122653630 Show fit | 0.68 |
ENST00000303924.4
|
hyaluronan synthase 2 |
|
| chr1_-_33283754 Show fit | 0.61 |
ENST00000373477.4
|
tyrosyl-tRNA synthetase |
Network of associatons between targets according to the STRING database.
First level regulatory network of GAUAUGU
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | GO:0090307 | mitotic spindle assembly(GO:0090307) |
| 0.3 | 1.0 | GO:0016344 | meiotic chromosome movement towards spindle pole(GO:0016344) |
| 0.1 | 1.0 | GO:0002326 | B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152) |
| 0.0 | 1.0 | GO:0019054 | modulation by virus of host process(GO:0019054) |
| 0.3 | 0.9 | GO:0003221 | right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
| 0.1 | 0.7 | GO:0070295 | renal water absorption(GO:0070295) |
| 0.1 | 0.7 | GO:0001675 | acrosome assembly(GO:0001675) |
| 0.0 | 0.7 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.1 | 0.6 | GO:1901843 | positive regulation of high voltage-gated calcium channel activity(GO:1901843) |
| 0.0 | 0.6 | GO:0060213 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.7 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 1.3 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.1 | 1.0 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.1 | 0.6 | GO:0017102 | methionyl glutamyl tRNA synthetase complex(GO:0017102) |
| 0.1 | 0.5 | GO:1990589 | ATF4-CREB1 transcription factor complex(GO:1990589) |
| 0.0 | 0.3 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.0 | 0.3 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.0 | 0.2 | GO:0005883 | neurofilament(GO:0005883) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 1.3 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.2 | 1.0 | GO:0070644 | vitamin D response element binding(GO:0070644) |
| 0.0 | 1.0 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.0 | 0.9 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.2 | 0.7 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 0.0 | 0.7 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 0.6 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.1 | 0.5 | GO:1990763 | arrestin family protein binding(GO:1990763) |
| 0.0 | 0.5 | GO:0030371 | translation repressor activity(GO:0030371) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.0 | 1.3 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 1.0 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 0.9 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.0 | 0.7 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 0.7 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 0.3 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 1.2 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 0.7 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.0 | 0.6 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.0 | 0.6 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.0 | 0.5 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
| 0.0 | 0.4 | REACTOME ACYL CHAIN REMODELLING OF PG | Genes involved in Acyl chain remodelling of PG |
| 0.0 | 0.4 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.0 | 0.3 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.0 | 0.3 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |