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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for GAUCAGA

Z-value: 0.05

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miRNA associated with seed GAUCAGA

NamemiRBASE accession
hsa-miR-383-5p.1
MIMAT0000738

Activity profile of GAUCAGA motif

Sorted Z-values of GAUCAGA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_183903133 0.39 ENST00000361354.4
NCKAP1
NCK-associated protein 1
chr3_+_197476621 0.25 ENST00000241502.4
FYTTD1
forty-two-three domain containing 1
chr2_-_200820459 0.13 ENST00000354611.4
TYW5
tRNA-yW synthesizing protein 5
chr17_-_27893990 0.12 ENST00000307201.4
ABHD15
abhydrolase domain containing 15
chr16_-_66785699 0.09 ENST00000258198.2
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr11_+_35684288 0.08 ENST00000299413.5
TRIM44
tripartite motif containing 44
chr16_-_46723066 0.07 ENST00000299138.7
VPS35
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr1_+_32930647 0.07 ENST00000609129.1
ZBTB8B
zinc finger and BTB domain containing 8B
chr18_+_54318616 0.07 ENST00000254442.3
WDR7
WD repeat domain 7
chr13_+_58206655 0.06 ENST00000377918.3
PCDH17
protocadherin 17
chr11_+_9406169 0.05 ENST00000379719.3
ENST00000527431.1
IPO7
importin 7
chr20_-_48099182 0.04 ENST00000371741.4
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr11_-_35440796 0.04 ENST00000278379.3
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr22_-_36236265 0.04 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chrX_-_107979616 0.04 ENST00000372129.2
IRS4
insulin receptor substrate 4
chr2_-_213403565 0.04 ENST00000342788.4
ENST00000436443.1
ERBB4
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
chr14_-_31495569 0.02 ENST00000357479.5
ENST00000355683.5
STRN3
striatin, calmodulin binding protein 3
chr20_-_18477862 0.01 ENST00000337227.4
RBBP9
retinoblastoma binding protein 9
chr11_-_108093329 0.01 ENST00000278612.8
NPAT
nuclear protein, ataxia-telangiectasia locus
chr11_-_118305921 0.01 ENST00000532619.1
RP11-770J1.4
RP11-770J1.4
chr4_+_144257915 0.00 ENST00000262995.4
GAB1
GRB2-associated binding protein 1
chr9_+_106856541 0.00 ENST00000286398.7
ENST00000440179.1
ENST00000374793.3
SMC2
structural maintenance of chromosomes 2

Network of associatons between targets according to the STRING database.

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:1903181 positive regulation of Wnt protein secretion(GO:0061357) regulation of late endosome to lysosome transport(GO:1902822) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) negative regulation of vacuolar transport(GO:1903336) negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.0 0.0 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.0 0.0 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)