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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for GGACGGA

Z-value: 0.52

Motif logo

miRNA associated with seed GGACGGA

NamemiRBASE accession
MIMAT0000454

Activity profile of GGACGGA motif

Sorted Z-values of GGACGGA motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_19229248 1.31 ENST00000375341.3
aldehyde dehydrogenase 4 family, member A1
chr11_+_117049445 0.88 ENST00000324225.4
ENST00000532960.1
SID1 transmembrane family, member 2
chr1_-_57045228 0.84 ENST00000371250.3
phosphatidic acid phosphatase type 2B
chr19_+_18794470 0.41 ENST00000321949.8
ENST00000338797.6
CREB regulated transcription coactivator 1
chr2_+_120770645 0.30 ENST00000443902.2
erythrocyte membrane protein band 4.1 like 5
chr10_+_102295616 0.15 ENST00000299163.6
hypoxia inducible factor 1, alpha subunit inhibitor
chr4_-_174451370 0.13 ENST00000359562.4
heart and neural crest derivatives expressed 2
chr19_+_3359561 0.09 ENST00000589123.1
ENST00000346156.5
ENST00000395111.3
ENST00000586919.1
nuclear factor I/C (CCAAT-binding transcription factor)
chr22_-_39268308 0.05 ENST00000407418.3
chromobox homolog 6

Network of associatons between targets according to the STRING database.

First level regulatory network of GGACGGA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 0.4 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 0.3 GO:0003383 apical constriction(GO:0003383) mesoderm migration involved in gastrulation(GO:0007509)
0.1 0.9 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0061032 cardiac right ventricle formation(GO:0003219) visceral serous pericardium development(GO:0061032)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 1.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis