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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
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Results for GGACGGA
Z-value: 0.52
Motif logo
miRNA associated with seed GGACGGA
| Name | miRBASE accession |
|---|---|
|
hsa-miR-184
|
MIMAT0000454 |
Activity profile of GGACGGA motif
Sorted Z-values of GGACGGA motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_-_19229248 | 1.31 |
ENST00000375341.3
|
ALDH4A1
|
aldehyde dehydrogenase 4 family, member A1 |
| chr11_+_117049445 | 0.88 |
ENST00000324225.4
ENST00000532960.1 |
SIDT2
|
SID1 transmembrane family, member 2 |
| chr1_-_57045228 | 0.84 |
ENST00000371250.3
|
PPAP2B
|
phosphatidic acid phosphatase type 2B |
| chr19_+_18794470 | 0.41 |
ENST00000321949.8
ENST00000338797.6 |
CRTC1
|
CREB regulated transcription coactivator 1 |
| chr2_+_120770645 | 0.30 |
ENST00000443902.2
|
EPB41L5
|
erythrocyte membrane protein band 4.1 like 5 |
| chr10_+_102295616 | 0.15 |
ENST00000299163.6
|
HIF1AN
|
hypoxia inducible factor 1, alpha subunit inhibitor |
| chr4_-_174451370 | 0.13 |
ENST00000359562.4
|
HAND2
|
heart and neural crest derivatives expressed 2 |
| chr19_+_3359561 | 0.09 |
ENST00000589123.1
ENST00000346156.5 ENST00000395111.3 ENST00000586919.1 |
NFIC
|
nuclear factor I/C (CCAAT-binding transcription factor) |
| chr22_-_39268308 | 0.05 |
ENST00000407418.3
|
CBX6
|
chromobox homolog 6 |
Network of associatons between targets according to the STRING database.
First level regulatory network of GGACGGA
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.3 | GO:0019470 | 4-hydroxyproline catabolic process(GO:0019470) |
| 0.1 | 0.4 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
| 0.1 | 0.3 | GO:0003383 | apical constriction(GO:0003383) mesoderm migration involved in gastrulation(GO:0007509) |
| 0.1 | 0.9 | GO:0033227 | dsRNA transport(GO:0033227) |
| 0.0 | 0.1 | GO:0042264 | peptidyl-aspartic acid hydroxylation(GO:0042264) |
| 0.0 | 0.1 | GO:0061032 | cardiac right ventricle formation(GO:0003219) visceral serous pericardium development(GO:0061032) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.9 | GO:0051033 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.1 | 1.3 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.0 | 0.4 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.0 | 0.1 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |