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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for GLIS2

Z-value: 0.28

Motif logo

Transcription factors associated with GLIS2

Gene Symbol Gene ID Gene Info
ENSG00000126603.4 GLIS family zinc finger 2

Activity profile of GLIS2 motif

Sorted Z-values of GLIS2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_18466026 11.47 ENST00000417717.2
SATB homeobox 1
chr19_+_45418067 10.99 ENST00000589078.1
ENST00000586638.1
apolipoprotein C-I
chr19_+_45409011 10.82 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
apolipoprotein E
chr19_+_45417504 9.43 ENST00000588750.1
ENST00000588802.1
apolipoprotein C-I
chr2_+_24272576 9.25 ENST00000380986.4
ENST00000452109.1
FK506 binding protein 1B, 12.6 kDa
chr20_+_30640004 8.77 ENST00000520553.1
ENST00000518730.1
ENST00000375852.2
hemopoietic cell kinase
chr19_+_45417812 8.62 ENST00000592535.1
apolipoprotein C-I
chr6_+_33048222 8.34 ENST00000428835.1
major histocompatibility complex, class II, DP beta 1
chr2_+_24272543 8.34 ENST00000380991.4
FK506 binding protein 1B, 12.6 kDa
chr19_+_45417921 7.76 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
apolipoprotein C-I
chr7_-_73133959 7.70 ENST00000395155.3
ENST00000395154.3
ENST00000222812.3
ENST00000395156.3
syntaxin 1A (brain)
chr19_+_45973120 7.36 ENST00000592811.1
ENST00000586615.1
FBJ murine osteosarcoma viral oncogene homolog B
chrX_+_102469997 7.20 ENST00000372695.5
ENST00000372691.3
brain expressed, X-linked 4
chr11_-_72353451 7.07 ENST00000376450.3
phosphodiesterase 2A, cGMP-stimulated
chr20_+_30639991 6.81 ENST00000534862.1
ENST00000538448.1
ENST00000375862.2
hemopoietic cell kinase
chr14_-_21493649 6.80 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG family member 2
chr14_-_21493884 6.70 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
NDRG family member 2
chr14_+_100150622 6.66 ENST00000261835.3
cytochrome P450, family 46, subfamily A, polypeptide 1
chr5_-_131826457 6.31 ENST00000437654.1
ENST00000245414.4
interferon regulatory factor 1
chr22_+_23264766 6.17 ENST00000390331.2
immunoglobulin lambda constant 7
chr11_-_64510409 5.96 ENST00000394429.1
ENST00000394428.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr19_-_54784937 5.73 ENST00000434421.1
ENST00000314446.5
ENST00000391749.4
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
chrX_-_102319092 5.69 ENST00000372728.3
brain expressed, X-linked 1
chr22_-_21213029 5.68 ENST00000572273.1
ENST00000255882.6
phosphatidylinositol 4-kinase, catalytic, alpha
chr16_-_29910853 5.60 ENST00000308713.5
seizure related 6 homolog (mouse)-like 2
chr8_+_27183033 5.44 ENST00000420218.2
protein tyrosine kinase 2 beta
chr20_+_44657845 5.34 ENST00000243964.3
solute carrier family 12 (potassium/chloride transporter), member 5
chr8_-_103136481 5.26 ENST00000524209.1
ENST00000517822.1
ENST00000523923.1
ENST00000521599.1
ENST00000521964.1
ENST00000311028.3
ENST00000518166.1
neurocalcin delta
chr16_-_29910365 5.21 ENST00000346932.5
ENST00000350527.3
ENST00000537485.1
ENST00000568380.1
seizure related 6 homolog (mouse)-like 2
chr6_-_32908792 5.03 ENST00000418107.2
major histocompatibility complex, class II, DM beta
chr11_+_121447469 5.03 ENST00000532694.1
ENST00000534286.1
sortilin-related receptor, L(DLR class) A repeats containing
chr20_+_57466461 4.97 ENST00000306090.10
GNAS complex locus
chr10_+_106014468 4.94 ENST00000369710.4
ENST00000369713.5
ENST00000445155.1
glutathione S-transferase omega 1
chr19_+_19322758 4.79 ENST00000252575.6
neurocan
chr1_-_36947120 4.59 ENST00000361632.4
colony stimulating factor 3 receptor (granulocyte)
chr1_-_19229248 4.17 ENST00000375341.3
aldehyde dehydrogenase 4 family, member A1
chrX_+_51927919 4.07 ENST00000416960.1
melanoma antigen family D, 4
chr2_+_102508955 4.05 ENST00000414004.2
FLJ20373
chr1_+_2487800 4.05 ENST00000355716.4
tumor necrosis factor receptor superfamily, member 14
chr11_-_615942 4.03 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
interferon regulatory factor 7
chr2_-_89310012 4.02 ENST00000493819.1
immunoglobulin kappa variable 1-9
chr8_-_134115118 4.02 ENST00000395352.3
ENST00000338087.5
Src-like-adaptor
chr8_+_27182862 3.95 ENST00000521164.1
ENST00000346049.5
protein tyrosine kinase 2 beta
chr7_-_158380371 3.84 ENST00000389418.4
ENST00000389416.4
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr6_+_44238203 3.56 ENST00000451188.2
transmembrane protein 151B
chr6_+_69345166 3.54 ENST00000370598.1
brain-specific angiogenesis inhibitor 3
chr19_+_17858509 3.53 ENST00000594202.1
ENST00000252771.7
ENST00000389133.4
FCH domain only 1
chr19_-_3061397 3.53 ENST00000586839.1
amino-terminal enhancer of split
chr6_-_2903514 3.47 ENST00000380698.4
serpin peptidase inhibitor, clade B (ovalbumin), member 9
chr1_-_153348067 3.36 ENST00000368737.3
S100 calcium binding protein A12
chr6_-_32908765 3.35 ENST00000416244.2
major histocompatibility complex, class II, DM beta
chr10_-_73848531 3.31 ENST00000373109.2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr9_+_117373486 3.30 ENST00000288502.4
ENST00000374049.4
chromosome 9 open reading frame 91
chr2_-_55277512 3.22 ENST00000402434.2
reticulon 4
chr19_+_17858547 3.20 ENST00000600676.1
ENST00000600209.1
ENST00000596309.1
ENST00000598539.1
ENST00000597474.1
ENST00000593385.1
ENST00000598067.1
ENST00000593833.1
FCH domain only 1
chr1_-_28520447 3.12 ENST00000539896.1
platelet-activating factor receptor
chr20_-_52687059 3.11 ENST00000371435.2
ENST00000395961.3
breast carcinoma amplified sequence 1
chr19_-_19006920 3.10 ENST00000429504.2
ENST00000427170.2
ceramide synthase 1
chr17_-_27224621 3.07 ENST00000394906.2
ENST00000585169.1
ENST00000394908.4
flotillin 2
chr11_-_615570 3.02 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
interferon regulatory factor 7
chr19_-_19006890 3.01 ENST00000247005.6
growth differentiation factor 1
chr19_-_2702681 3.00 ENST00000382159.3
guanine nucleotide binding protein (G protein), gamma 7
chr3_+_4535025 2.99 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
inositol 1,4,5-trisphosphate receptor, type 1
chr2_+_220492373 2.94 ENST00000317151.3
solute carrier family 4 (anion exchanger), member 3
chr19_-_39108568 2.93 ENST00000586296.1
mitogen-activated protein kinase kinase kinase kinase 1
chr7_-_158380465 2.93 ENST00000389413.3
ENST00000409483.1
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr17_+_78075361 2.92 ENST00000577106.1
ENST00000390015.3
glucosidase, alpha; acid
chr10_-_75634219 2.86 ENST00000305762.7
calcium/calmodulin-dependent protein kinase II gamma
chr1_-_40157345 2.80 ENST00000372844.3
hippocalcin like 4
chr8_+_41347915 2.80 ENST00000518270.1
ENST00000520817.1
golgin A7
chr17_-_4871085 2.79 ENST00000575142.1
ENST00000206020.3
sperm associated antigen 7
chr17_+_7461580 2.77 ENST00000483039.1
ENST00000396542.1
tumor necrosis factor (ligand) superfamily, member 13
chr5_-_1524015 2.75 ENST00000283415.3
lysophosphatidylcholine acyltransferase 1
chr2_+_131113580 2.74 ENST00000175756.5
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
chr3_+_54157480 2.73 ENST00000490478.1
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr7_-_752577 2.70 ENST00000544935.1
ENST00000430040.1
ENST00000456696.2
ENST00000406797.1
protein kinase, cAMP-dependent, regulatory, type I, beta
chr2_-_55277654 2.66 ENST00000337526.6
ENST00000317610.7
ENST00000357732.4
reticulon 4
chr2_+_169312350 2.65 ENST00000305747.6
ceramide synthase 6
chr12_-_57941004 2.58 ENST00000550750.1
ENST00000548249.1
dynactin 2 (p50)
chrX_+_153656978 2.52 ENST00000369762.2
ENST00000422890.1
ATPase, H+ transporting, lysosomal accessory protein 1
chr7_+_75544397 2.50 ENST00000461988.1
ENST00000419840.1
P450 (cytochrome) oxidoreductase
chr19_+_17186577 2.49 ENST00000595618.1
ENST00000594824.1
myosin IXB
chr16_+_2198604 2.48 ENST00000210187.6
RAB26, member RAS oncogene family
chr3_-_48470838 2.48 ENST00000358459.4
ENST00000358536.4
plexin B1
chr3_+_153839149 2.47 ENST00000465093.1
ENST00000465817.1
Rho guanine nucleotide exchange factor (GEF) 26
chr8_+_41348173 2.46 ENST00000357743.4
golgin A7
chr2_+_131113609 2.45 ENST00000347849.3
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
chr20_+_57466357 2.44 ENST00000371095.3
ENST00000371085.3
ENST00000354359.7
ENST00000265620.7
GNAS complex locus
chr2_-_55277692 2.44 ENST00000394611.2
reticulon 4
chr16_-_89556942 2.43 ENST00000301030.4
ankyrin repeat domain 11
chr3_+_183903811 2.41 ENST00000429586.2
ENST00000292808.5
ATP-binding cassette, sub-family F (GCN20), member 3
chrX_+_1710484 2.40 ENST00000313871.3
ENST00000381261.3
A kinase (PRKA) anchor protein 17A
chr12_-_57940904 2.40 ENST00000550954.1
ENST00000434715.3
ENST00000546670.1
ENST00000543672.1
dynactin 2 (p50)
chr7_+_75544466 2.37 ENST00000421059.1
ENST00000394893.1
ENST00000412521.1
ENST00000414186.1
P450 (cytochrome) oxidoreductase
chr19_+_7733929 2.36 ENST00000221515.2
resistin
chr15_+_81475047 2.33 ENST00000559388.1
interleukin 16
chr11_-_61197187 2.27 ENST00000449811.1
ENST00000413232.1
ENST00000340437.4
ENST00000539952.1
ENST00000544585.1
ENST00000450000.1
cleavage and polyadenylation specific factor 7, 59kDa
chr1_-_201346761 2.23 ENST00000455702.1
ENST00000422165.1
ENST00000367318.5
ENST00000367320.2
ENST00000438742.1
ENST00000412633.1
ENST00000458432.2
ENST00000421663.2
ENST00000367322.1
ENST00000509001.1
troponin T type 2 (cardiac)
chr11_+_63753883 2.23 ENST00000538426.1
ENST00000543004.1
OTU domain, ubiquitin aldehyde binding 1
chr22_+_22681656 2.21 ENST00000390291.2
immunoglobulin lambda variable 1-50 (non-functional)
chr4_+_40058411 2.21 ENST00000261435.6
ENST00000515550.1
NEDD4 binding protein 2
chr19_+_10765699 2.21 ENST00000590009.1
interleukin enhancer binding factor 3, 90kDa
chr22_-_18256742 2.20 ENST00000317361.7
BH3 interacting domain death agonist
chr8_+_41348072 2.19 ENST00000405786.2
golgin A7
chr16_+_67198683 2.18 ENST00000517685.1
ENST00000521374.1
ENST00000584272.1
heat shock transcription factor 4
chr6_+_29624862 2.16 ENST00000376894.4
myelin oligodendrocyte glycoprotein
chr7_+_87257701 2.15 ENST00000338056.3
ENST00000493037.1
RUN domain containing 3B
chr19_+_49622646 2.12 ENST00000334186.4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr19_+_55105085 2.11 ENST00000251372.3
ENST00000453777.1
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
chr19_+_54372639 2.10 ENST00000391769.2
myeloid-associated differentiation marker
chr3_-_125803105 2.07 ENST00000346785.5
ENST00000315891.6
solute carrier family 41, member 3
chr20_+_44637526 2.06 ENST00000372330.3
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chrX_+_102631844 2.06 ENST00000372634.1
ENST00000299872.7
nerve growth factor receptor (TNFRSF16) associated protein 1
chr14_+_24540731 2.06 ENST00000558859.1
ENST00000559197.1
ENST00000560828.1
ENST00000216775.2
ENST00000560884.1
copine VI (neuronal)
chr19_+_17337406 2.03 ENST00000597836.1
occludin/ELL domain containing 1
chr4_+_114214125 2.02 ENST00000509550.1
ankyrin 2, neuronal
chr6_+_29624758 2.01 ENST00000376917.3
ENST00000376902.3
ENST00000533330.2
ENST00000376888.2
myelin oligodendrocyte glycoprotein
chr3_-_125802765 2.00 ENST00000514891.1
ENST00000512470.1
ENST00000504035.1
ENST00000360370.4
ENST00000513723.1
ENST00000510651.1
ENST00000514333.1
solute carrier family 41, member 3
chr17_-_76719807 1.98 ENST00000589297.1
cytohesin 1
chr22_-_18257249 1.96 ENST00000399765.1
ENST00000399767.1
ENST00000399774.3
BH3 interacting domain death agonist
chr22_-_18257178 1.95 ENST00000342111.5
BH3 interacting domain death agonist
chr2_+_169312725 1.93 ENST00000392687.4
ceramide synthase 6
chr6_+_29624898 1.89 ENST00000396704.3
ENST00000483013.1
ENST00000490427.1
ENST00000416766.2
ENST00000376891.4
ENST00000376898.3
ENST00000396701.2
ENST00000494692.1
ENST00000431798.2
myelin oligodendrocyte glycoprotein
chr15_+_42694573 1.84 ENST00000397200.4
ENST00000569827.1
calpain 3, (p94)
chr16_+_765092 1.83 ENST00000568223.2
meteorin, glial cell differentiation regulator
chr1_+_1950763 1.79 ENST00000378585.4
gamma-aminobutyric acid (GABA) A receptor, delta
chr7_+_87257854 1.76 ENST00000394654.3
RUN domain containing 3B
chr11_-_64646086 1.73 ENST00000320631.3
EH-domain containing 1
chr9_-_35112376 1.70 ENST00000488109.2
family with sequence similarity 214, member B
chr2_+_46769798 1.69 ENST00000238738.4
ras homolog family member Q
chr2_-_27718052 1.69 ENST00000264703.3
fibronectin type III domain containing 4
chr5_-_180237445 1.65 ENST00000393340.3
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr19_-_17414179 1.64 ENST00000594194.1
ENST00000247706.3
abhydrolase domain containing 8
chr17_-_42200996 1.62 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
histone deacetylase 5
chr6_+_28109703 1.61 ENST00000457389.2
ENST00000330236.6
zinc finger with KRAB and SCAN domains 8
chr3_+_4535155 1.60 ENST00000544951.1
inositol 1,4,5-trisphosphate receptor, type 1
chr2_+_37571717 1.60 ENST00000338415.3
ENST00000404976.1
glutaminyl-peptide cyclotransferase
chr17_-_5138099 1.59 ENST00000571800.1
ENST00000574081.1
ENST00000399600.4
ENST00000574297.1
SLP adaptor and CSK interacting membrane protein
chr19_+_56186557 1.57 ENST00000270460.6
epsin 1
chr19_-_6720686 1.55 ENST00000245907.6
complement component 3
chr6_+_31926857 1.54 ENST00000375394.2
ENST00000544581.1
superkiller viralicidic activity 2-like (S. cerevisiae)
chr19_-_39108643 1.54 ENST00000396857.2
mitogen-activated protein kinase kinase kinase kinase 1
chr17_+_5389605 1.53 ENST00000576988.1
ENST00000576570.1
ENST00000573759.1
MIS12 kinetochore complex component
chr20_-_34638841 1.53 ENST00000565493.1
long intergenic non-protein coding RNA 657
chr19_-_17799008 1.53 ENST00000519716.2
unc-13 homolog A (C. elegans)
chr19_-_36643329 1.51 ENST00000589154.1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr22_+_22786288 1.51 ENST00000390301.2
immunoglobulin lambda variable 1-36
chr11_-_61197480 1.51 ENST00000439958.3
ENST00000394888.4
cleavage and polyadenylation specific factor 7, 59kDa
chr12_+_50451462 1.49 ENST00000447966.2
acid-sensing (proton-gated) ion channel 1
chr17_-_41985096 1.49 ENST00000269095.4
ENST00000523220.1
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr17_-_47755338 1.47 ENST00000508805.1
ENST00000515508.2
ENST00000451526.2
ENST00000507970.1
speckle-type POZ protein
chr1_-_24127256 1.47 ENST00000418277.1
UDP-galactose-4-epimerase
chr3_+_151531810 1.44 ENST00000232892.7
arylacetamide deacetylase
chr19_-_821931 1.43 ENST00000359894.2
ENST00000520876.3
ENST00000519502.1
hsa-mir-3187
chr22_-_38794490 1.41 ENST00000400206.2
casein kinase 1, epsilon
chr22_-_32026810 1.39 ENST00000266095.5
ENST00000397500.1
phosphatidylserine decarboxylase
chr7_-_130080818 1.39 ENST00000343969.5
ENST00000541543.1
ENST00000489512.1
centrosomal protein 41kDa
chr17_-_34257731 1.39 ENST00000431884.2
ENST00000425909.3
ENST00000394528.3
ENST00000430160.2
RAD52 motif 1
chr19_-_39108552 1.39 ENST00000591517.1
mitogen-activated protein kinase kinase kinase kinase 1
chrX_+_48660287 1.37 ENST00000444343.2
ENST00000376610.2
ENST00000334136.5
ENST00000376619.2
histone deacetylase 6
chr17_+_38278826 1.36 ENST00000577454.1
ENST00000578648.1
ENST00000579565.1
male-specific lethal 1 homolog (Drosophila)
chr19_+_56159509 1.36 ENST00000586790.1
ENST00000591578.1
ENST00000588740.1
coiled-coil domain containing 106
chr6_+_17393839 1.34 ENST00000489374.1
ENST00000378990.2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr22_-_19974616 1.32 ENST00000344269.3
ENST00000401994.1
ENST00000406522.1
armadillo repeat gene deleted in velocardiofacial syndrome
chr17_+_80014359 1.31 ENST00000578168.1
G protein pathway suppressor 1
chr10_-_104179682 1.30 ENST00000406432.1
pleckstrin and Sec7 domain containing
chr14_-_105635090 1.29 ENST00000331782.3
ENST00000347004.2
jagged 2
chr20_+_57226284 1.26 ENST00000458280.1
ENST00000355957.5
ENST00000361770.5
ENST00000312283.8
ENST00000412911.1
ENST00000359617.4
ENST00000371141.4
syntaxin 16
chr16_-_29415350 1.26 ENST00000524087.1
nuclear pore complex interacting protein family, member B11
chr17_+_6659153 1.26 ENST00000441631.1
ENST00000438512.1
ENST00000346752.4
ENST00000361842.3
XIAP associated factor 1
chr13_-_108867846 1.25 ENST00000442234.1
ligase IV, DNA, ATP-dependent
chr7_-_752074 1.24 ENST00000360274.4
protein kinase, cAMP-dependent, regulatory, type I, beta
chr6_+_43457317 1.23 ENST00000438588.2
tight junction associated protein 1 (peripheral)
chr19_+_56159362 1.23 ENST00000593069.1
ENST00000308964.3
coiled-coil domain containing 106
chr19_+_10527449 1.21 ENST00000592685.1
ENST00000380702.2
phosphodiesterase 4A, cAMP-specific
chr19_+_17337473 1.19 ENST00000598068.1
occludin/ELL domain containing 1
chr17_-_7120525 1.19 ENST00000447163.1
ENST00000399506.2
ENST00000302955.6
discs, large homolog 4 (Drosophila)
chr20_+_48807351 1.19 ENST00000303004.3
CCAAT/enhancer binding protein (C/EBP), beta
chr19_-_8408139 1.16 ENST00000330915.3
ENST00000593649.1
ENST00000595639.1
KN motif and ankyrin repeat domains 3
chrX_-_2418936 1.13 ENST00000461691.1
ENST00000381223.4
ENST00000381222.2
ENST00000412516.2
ENST00000334651.5
zinc finger, BED-type containing 1
dehydrogenase/reductase (SDR family) X-linked
chr12_+_57853918 1.12 ENST00000532291.1
ENST00000543426.1
ENST00000228682.2
ENST00000546141.1
GLI family zinc finger 1
chr10_+_43633914 1.12 ENST00000374466.3
ENST00000374464.1
chondroitin sulfate N-acetylgalactosaminyltransferase 2
chr7_+_29237354 1.12 ENST00000546235.1
chimerin 2
chr17_+_7788104 1.11 ENST00000380358.4
chromodomain helicase DNA binding protein 3
chr16_-_29934558 1.10 ENST00000568995.1
ENST00000566413.1
potassium channel tetramerization domain containing 13
chr1_-_235292250 1.09 ENST00000366607.4
translocase of outer mitochondrial membrane 20 homolog (yeast)
chr2_+_37571845 1.09 ENST00000537448.1
glutaminyl-peptide cyclotransferase
chr9_+_139839686 1.08 ENST00000371634.2
complement component 8, gamma polypeptide
chr19_-_5340730 1.07 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
protein tyrosine phosphatase, receptor type, S
chr17_+_80416050 1.06 ENST00000579198.1
ENST00000390006.4
ENST00000580296.1
nuclear prelamin A recognition factor
chr22_+_21400229 1.04 ENST00000342608.4
ENST00000543388.1
ENST00000442047.1
Leucine-rich repeat-containing protein LOC400891
chrX_-_153744434 1.04 ENST00000369643.1
ENST00000393572.1
family with sequence similarity 3, member A
chr2_+_71357744 1.03 ENST00000498451.2
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr12_+_121837844 1.03 ENST00000361234.5
ring finger protein 34, E3 ubiquitin protein ligase
chr15_+_69307028 1.01 ENST00000388866.3
ENST00000530406.2
NADPH oxidase, EF-hand calcium binding domain 5
chr21_-_39288743 1.01 ENST00000609713.1
potassium inwardly-rectifying channel, subfamily J, member 6
chrX_-_8700171 0.99 ENST00000262648.3
Kallmann syndrome 1 sequence
chr19_+_16830774 0.98 ENST00000524140.2
NACHT and WD repeat domain containing 1
chr12_+_112563335 0.96 ENST00000549358.1
ENST00000257604.5
ENST00000548092.1
ENST00000552896.1
TRAF-type zinc finger domain containing 1
chr19_+_41103063 0.95 ENST00000308370.7
latent transforming growth factor beta binding protein 4

Network of associatons between targets according to the STRING database.

First level regulatory network of GLIS2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
9.2 36.8 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
5.2 15.6 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
3.6 10.8 GO:1902995 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
2.8 8.4 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
2.7 13.4 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
2.4 7.1 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
2.3 9.4 GO:2000537 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
1.9 7.7 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
1.8 17.6 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
1.7 5.0 GO:1902955 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
1.6 4.9 GO:0043602 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210)
1.5 7.5 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
1.3 5.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
1.2 3.5 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
1.1 2.2 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
1.1 7.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
1.0 4.2 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
1.0 3.1 GO:1904317 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.9 8.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.9 4.6 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.9 2.7 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.9 2.7 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.9 13.7 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.8 2.5 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.8 4.9 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.8 4.0 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.8 2.4 GO:2000196 positive regulation of female gonad development(GO:2000196) regulation of progesterone secretion(GO:2000870)
0.8 3.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.8 11.5 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.7 3.0 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.7 6.7 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.7 2.9 GO:0002086 maltose metabolic process(GO:0000023) diaphragm contraction(GO:0002086)
0.7 5.7 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.7 2.0 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.7 2.0 GO:0061760 antifungal innate immune response(GO:0061760)
0.6 2.5 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.6 6.1 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.5 1.6 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.5 1.0 GO:2000374 regulation of oxygen metabolic process(GO:2000374)
0.5 3.1 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.5 1.4 GO:0090034 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.4 1.3 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.4 1.7 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.4 1.6 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.4 1.5 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.4 1.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.3 2.1 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.3 1.0 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.3 2.3 GO:0050915 sensory perception of sour taste(GO:0050915)
0.3 3.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 3.5 GO:2000210 positive regulation of anoikis(GO:2000210)
0.3 2.2 GO:1902915 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.3 1.8 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.3 3.6 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.3 7.4 GO:0051412 response to corticosterone(GO:0051412)
0.3 1.1 GO:0021938 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.3 1.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.3 5.8 GO:0032011 ARF protein signal transduction(GO:0032011)
0.3 1.1 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.3 0.8 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.2 3.9 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 1.5 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.2 1.2 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.2 1.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.2 6.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 2.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 4.0 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2 4.6 GO:0097186 amelogenesis(GO:0097186)
0.2 2.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.2 4.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.2 5.7 GO:0044803 multi-organism membrane organization(GO:0044803)
0.2 0.8 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.2 1.5 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.2 5.0 GO:0071539 protein localization to centrosome(GO:0071539)
0.2 4.8 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.2 1.3 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.2 6.1 GO:0046718 viral entry into host cell(GO:0046718)
0.2 0.3 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.2 0.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.2 1.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.2 0.6 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.2 0.3 GO:0097327 response to antineoplastic agent(GO:0097327)
0.2 0.6 GO:0006272 leading strand elongation(GO:0006272)
0.2 2.9 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.1 8.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 1.4 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.4 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.7 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.2 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 1.5 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.7 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.4 GO:0019046 release from viral latency(GO:0019046)
0.1 2.3 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 1.6 GO:0070374 positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.1 0.5 GO:0015692 lead ion transport(GO:0015692)
0.1 2.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.1 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.1 3.9 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.1 8.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 3.4 GO:0050832 defense response to fungus(GO:0050832)
0.1 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 1.6 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.7 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 1.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 6.1 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.1 0.8 GO:0032055 negative regulation of translation in response to stress(GO:0032055) circadian regulation of translation(GO:0097167)
0.1 0.3 GO:2000547 dendritic cell dendrite assembly(GO:0097026) regulation of dendritic cell dendrite assembly(GO:2000547)
0.1 1.4 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.1 5.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.3 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 1.6 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.1 0.9 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.1 0.8 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 4.6 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 2.4 GO:0060325 face morphogenesis(GO:0060325)
0.1 1.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.4 GO:0072553 terminal button organization(GO:0072553)
0.1 0.4 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.1 0.2 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.5 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.1 4.7 GO:0048278 vesicle docking(GO:0048278)
0.1 0.5 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.1 2.3 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.1 0.5 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 1.1 GO:0032060 bleb assembly(GO:0032060)
0.1 0.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 1.4 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 3.0 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 1.7 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 7.3 GO:0002377 immunoglobulin production(GO:0002377)
0.0 1.6 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 1.6 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.6 GO:0021794 thalamus development(GO:0021794)
0.0 1.1 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.8 GO:0033081 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0 1.5 GO:0046710 GDP metabolic process(GO:0046710)
0.0 1.3 GO:0035456 response to interferon-beta(GO:0035456)
0.0 1.0 GO:0030252 growth hormone secretion(GO:0030252)
0.0 2.7 GO:1901185 negative regulation of ERBB signaling pathway(GO:1901185)
0.0 2.2 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.5 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.6 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.0 GO:0072402 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 1.0 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.7 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.8 GO:0007030 Golgi organization(GO:0007030)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 2.7 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.3 GO:0010001 glial cell differentiation(GO:0010001)
0.0 0.3 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.9 GO:0071357 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 3.8 GO:0051262 protein tetramerization(GO:0051262)
0.0 0.7 GO:0033198 response to ATP(GO:0033198)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.9 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 2.7 GO:0042113 B cell activation(GO:0042113)
0.0 0.7 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 1.1 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.8 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 1.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 1.5 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.6 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.2 GO:0070997 neuron death(GO:0070997)
0.0 2.1 GO:0002250 adaptive immune response(GO:0002250)
0.0 0.4 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.9 GO:0022900 electron transport chain(GO:0022900)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.8 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
1.9 7.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
1.9 5.7 GO:0019034 viral replication complex(GO:0019034)
1.7 37.4 GO:0042627 chylomicron(GO:0042627)
1.1 7.5 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.8 16.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.6 3.8 GO:1990584 cardiac Troponin complex(GO:1990584)
0.6 9.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.5 1.5 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.5 1.5 GO:0044305 calyx of Held(GO:0044305)
0.5 4.6 GO:0005955 calcineurin complex(GO:0005955)
0.4 8.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.4 2.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.4 20.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.4 1.5 GO:0055087 Ski complex(GO:0055087)
0.4 5.3 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.4 4.9 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.3 5.0 GO:0005869 dynactin complex(GO:0005869)
0.3 11.5 GO:0005720 nuclear heterochromatin(GO:0005720)
0.2 3.1 GO:0016600 flotillin complex(GO:0016600)
0.2 1.3 GO:0032807 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.2 1.7 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.2 1.0 GO:0034457 Mpp10 complex(GO:0034457)
0.2 1.8 GO:0005579 membrane attack complex(GO:0005579)
0.2 3.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 1.4 GO:0072487 MSL complex(GO:0072487)
0.2 10.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 2.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 3.8 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.2 23.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.2 15.4 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.2 1.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 1.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.6 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 1.1 GO:0005638 lamin filament(GO:0005638)
0.1 5.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.1 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 6.1 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.1 0.5 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 2.1 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.5 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 8.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 4.9 GO:0043198 dendritic shaft(GO:0043198)
0.1 1.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.1 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 7.1 GO:0042734 presynaptic membrane(GO:0042734)
0.1 0.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 8.9 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.8 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.6 GO:0072357 glycogen granule(GO:0042587) PTW/PP1 phosphatase complex(GO:0072357)
0.1 3.9 GO:0030315 T-tubule(GO:0030315)
0.1 0.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 3.1 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 2.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 4.8 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 1.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 1.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 8.3 GO:0030426 growth cone(GO:0030426)
0.1 1.7 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 6.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 3.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 0.8 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 1.1 GO:0097546 ciliary base(GO:0097546)
0.0 1.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 3.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 3.5 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.0 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 1.4 GO:0030286 dynein complex(GO:0030286)
0.0 0.3 GO:0098576 lumenal side of membrane(GO:0098576)
0.0 0.7 GO:0031082 BLOC complex(GO:0031082)
0.0 2.5 GO:0016459 myosin complex(GO:0016459)
0.0 1.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 1.9 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.2 GO:0032797 SMN complex(GO:0032797) Gemini of coiled bodies(GO:0097504)
0.0 0.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.5 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 15.6 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.9 GO:0015030 Cajal body(GO:0015030)
0.0 0.7 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 3.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 5.0 GO:0010008 endosome membrane(GO:0010008)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.9 GO:0036064 ciliary basal body(GO:0036064)
0.0 2.0 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.9 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
6.0 47.6 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
3.5 17.6 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
3.1 9.4 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
1.6 4.9 GO:0045174 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
1.6 4.9 GO:0047726 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
1.3 7.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
1.2 7.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
1.1 4.6 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
1.1 4.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
1.0 2.9 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.9 5.7 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.9 2.7 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.8 2.5 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.8 9.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.7 5.7 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
0.7 7.4 GO:0051430 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.6 3.1 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.6 1.7 GO:0032427 GBD domain binding(GO:0032427)
0.6 2.2 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.5 7.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.5 5.3 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.5 2.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.5 1.4 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.4 6.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.4 7.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.4 1.6 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.4 1.6 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.4 1.2 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.3 1.4 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.3 1.6 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.3 5.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.3 1.1 GO:0004803 transposase activity(GO:0004803)
0.3 6.8 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.3 8.7 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.3 2.5 GO:0048495 Roundabout binding(GO:0048495)
0.3 0.8 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.3 0.8 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.3 15.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.3 4.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 8.3 GO:0042605 peptide antigen binding(GO:0042605)
0.2 1.1 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.2 2.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.2 2.9 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.2 3.9 GO:0008603 cAMP-dependent protein kinase inhibitor activity(GO:0004862) cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 6.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.2 6.1 GO:0005123 death receptor binding(GO:0005123)
0.2 2.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 4.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.2 0.5 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.2 1.0 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.2 3.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 4.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 2.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 4.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 3.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.6 GO:0042954 apolipoprotein receptor activity(GO:0030226) lipoprotein transporter activity(GO:0042954)
0.1 4.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 1.1 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.9 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 1.3 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 1.8 GO:0031432 titin binding(GO:0031432)
0.1 2.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 6.4 GO:0030507 spectrin binding(GO:0030507)
0.1 3.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 1.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.5 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.1 0.5 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 3.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.6 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 5.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.3 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 2.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 3.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 1.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 4.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.4 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1 2.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 7.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 0.5 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 1.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 1.3 GO:0005112 Notch binding(GO:0005112)
0.1 4.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.4 GO:0030172 troponin C binding(GO:0030172)
0.1 1.8 GO:0001848 complement binding(GO:0001848)
0.1 3.1 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 0.7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 1.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 5.8 GO:0001618 virus receptor activity(GO:0001618)
0.1 2.4 GO:0051018 protein kinase A binding(GO:0051018)
0.1 0.4 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.6 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 1.5 GO:0016675 oxidoreductase activity, acting on a heme group of donors(GO:0016675)
0.0 1.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.6 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 1.2 GO:0030552 cAMP binding(GO:0030552)
0.0 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.0 1.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 13.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.4 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.5 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 1.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.8 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.7 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.3 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 2.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.6 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.5 GO:0070035 ATP-dependent RNA helicase activity(GO:0004004) ATP-dependent helicase activity(GO:0008026) RNA-dependent ATPase activity(GO:0008186) purine NTP-dependent helicase activity(GO:0070035)
0.0 5.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.6 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 1.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 7.6 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 3.2 GO:0022832 voltage-gated ion channel activity(GO:0005244) voltage-gated channel activity(GO:0022832)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.8 GO:0043022 ribosome binding(GO:0043022)
0.0 1.7 GO:0003823 antigen binding(GO:0003823)
0.0 1.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.0 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.2 GO:0031005 filamin binding(GO:0031005)
0.0 2.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.6 GO:0004866 endopeptidase inhibitor activity(GO:0004866)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 15.6 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.3 9.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3 5.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 10.7 PID IFNG PATHWAY IFN-gamma pathway
0.2 6.5 PID RAS PATHWAY Regulation of Ras family activation
0.2 6.7 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 12.1 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 8.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 13.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 13.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 3.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 2.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 4.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 1.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 2.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 4.6 PID AP1 PATHWAY AP-1 transcription factor network
0.1 3.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 1.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 1.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.8 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 2.0 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 4.6 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.0 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 1.3 PID NOTCH PATHWAY Notch signaling pathway
0.0 2.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.8 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.3 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 7.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 2.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.5 7.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.5 10.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.4 15.6 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.4 7.7 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.4 11.3 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.4 8.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.3 9.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.3 5.7 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 6.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 5.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 3.8 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.2 6.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.2 3.9 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.2 2.7 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.2 7.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.2 6.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.2 6.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 4.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 4.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 3.4 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 1.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 9.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 13.4 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 3.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 6.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.6 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 1.9 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.6 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 1.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 3.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 2.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 2.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 3.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 0.7 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 6.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 0.5 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 2.3 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 2.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 1.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 5.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.6 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 1.9 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 2.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 2.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.7 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 1.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.1 REACTOME STRIATED MUSCLE CONTRACTION