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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for GMEB1

Z-value: 0.01

Motif logo

Transcription factors associated with GMEB1

Gene Symbol Gene ID Gene Info
ENSG00000162419.8 glucocorticoid modulatory element binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GMEB1hg19_v2_chr1_+_28995231_289952500.073.3e-01Click!

Activity profile of GMEB1 motif

Sorted Z-values of GMEB1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_57831829 5.92 ENST00000321545.4
zinc finger protein 543
chr1_+_202830876 4.21 ENST00000456105.2
RP11-480I12.7
chr12_+_75784850 3.84 ENST00000550916.1
ENST00000435775.1
ENST00000378689.2
ENST00000378692.3
ENST00000320460.4
ENST00000547164.1
GLI pathogenesis-related 1 like 2
chr3_+_122296465 3.82 ENST00000483793.1
poly (ADP-ribose) polymerase family, member 15
chr3_+_62304648 3.79 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
chromosome 3 open reading frame 14
chr4_-_83719884 3.51 ENST00000282709.4
ENST00000273908.4
stearoyl-CoA desaturase 5
chr3_+_62304712 3.46 ENST00000494481.1
chromosome 3 open reading frame 14
chr7_+_35840819 3.43 ENST00000399035.3
septin 7
chr1_+_46668994 3.39 ENST00000371980.3
leucine rich adaptor protein 1
chr6_-_24667180 3.37 ENST00000545995.1
tyrosyl-DNA phosphodiesterase 2
chr7_+_120590803 3.27 ENST00000315870.5
ENST00000339121.5
ENST00000445699.1
inhibitor of growth family, member 3
chr10_+_28821674 3.21 ENST00000526722.1
ENST00000375646.1
WW domain containing adaptor with coiled-coil
chr3_-_134204815 3.18 ENST00000514612.1
ENST00000510994.1
ENST00000354910.5
anaphase promoting complex subunit 13
chr3_+_134204881 3.11 ENST00000511574.1
ENST00000337090.3
ENST00000383229.3
centrosomal protein 63kDa
chr3_+_134205000 3.05 ENST00000512894.1
ENST00000513612.2
ENST00000606977.1
centrosomal protein 63kDa
chr3_-_98241358 3.05 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
claudin domain containing 1
chrX_+_64887512 3.02 ENST00000360270.5
moesin
chr7_+_35840542 3.01 ENST00000435235.1
ENST00000399034.2
ENST00000350320.6
ENST00000469679.2
septin 7
chr14_-_35591433 2.97 ENST00000261475.5
ENST00000555644.1
protein phosphatase 2, regulatory subunit B'', gamma
chrX_-_149106653 2.95 ENST00000462691.1
ENST00000370404.1
ENST00000483447.1
ENST00000370409.3
chromosome X open reading frame 40B
chr1_-_155881156 2.88 ENST00000539040.1
ENST00000368323.3
Ras-like without CAAX 1
chr3_+_197476621 2.85 ENST00000241502.4
forty-two-three domain containing 1
chr8_+_64081214 2.80 ENST00000542911.2
YTH domain family, member 3
chr7_+_120591170 2.78 ENST00000431467.1
inhibitor of growth family, member 3
chr4_+_113558272 2.73 ENST00000509061.1
ENST00000508577.1
ENST00000513553.1
La ribonucleoprotein domain family, member 7
chr6_-_24666819 2.73 ENST00000341060.3
tyrosyl-DNA phosphodiesterase 2
chr14_+_35591858 2.71 ENST00000603544.1
KIAA0391
chr6_+_106959718 2.65 ENST00000369066.3
absent in melanoma 1
chr1_-_63988846 2.62 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
integrin beta 3 binding protein (beta3-endonexin)
chr6_+_88299833 2.59 ENST00000392844.3
ENST00000257789.4
ENST00000546266.1
ENST00000417380.2
origin recognition complex, subunit 3
chr8_+_109455845 2.57 ENST00000220853.3
ER membrane protein complex subunit 2
chr1_+_145516560 2.57 ENST00000537888.1
peroxisomal biogenesis factor 11 beta
chr1_-_246729544 2.57 ENST00000544618.1
ENST00000366514.4
transcription factor B2, mitochondrial
chr2_+_187350883 2.55 ENST00000337859.6
zinc finger CCCH-type containing 15
chr1_+_162531294 2.51 ENST00000367926.4
ENST00000271469.3
UDP-N-acteylglucosamine pyrophosphorylase 1
chr5_+_140071178 2.51 ENST00000508522.1
ENST00000448069.2
histidyl-tRNA synthetase 2, mitochondrial
chr16_-_20753114 2.49 ENST00000396083.2
THUMP domain containing 1
chr2_-_99952769 2.45 ENST00000409434.1
ENST00000434323.1
ENST00000264255.3
thioredoxin domain containing 9
chrX_+_148622513 2.44 ENST00000393985.3
ENST00000423421.1
ENST00000423540.2
ENST00000434353.2
ENST00000514208.1
chromosome X open reading frame 40A
chr3_-_81811312 2.41 ENST00000429644.2
glucan (1,4-alpha-), branching enzyme 1
chr14_+_35591928 2.41 ENST00000605870.1
ENST00000557404.3
KIAA0391
chr5_-_68665296 2.40 ENST00000512152.1
ENST00000503245.1
ENST00000512561.1
ENST00000380822.4
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr1_+_110162448 2.39 ENST00000342115.4
ENST00000469039.2
ENST00000474459.1
ENST00000528667.1
adenosine monophosphate deaminase 2
chr19_-_23941639 2.38 ENST00000395385.3
ENST00000531570.1
ENST00000528059.1
zinc finger protein 681
chr2_+_187350973 2.34 ENST00000544130.1
zinc finger CCCH-type containing 15
chr15_-_55581954 2.33 ENST00000336787.1
RAB27A, member RAS oncogene family
chr8_+_64081118 2.31 ENST00000539294.1
YTH domain family, member 3
chr6_+_116892530 2.27 ENST00000466444.2
ENST00000368590.5
ENST00000392526.1
RWD domain containing 1
chr11_+_114270752 2.26 ENST00000540163.1
RNA binding motif protein 7
chr13_-_23949671 2.24 ENST00000402364.1
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr6_+_116892641 2.21 ENST00000487832.2
ENST00000518117.1
RWD domain containing 1
chr16_-_67969888 2.21 ENST00000574576.2
proteasome (prosome, macropain) subunit, beta type, 10
chr17_-_9479128 2.20 ENST00000574431.1
syntaxin 8
chr6_+_32821924 2.19 ENST00000374859.2
ENST00000453265.2
proteasome (prosome, macropain) subunit, beta type, 9
chr11_-_65667884 2.18 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOS-like antigen 1
chr11_+_95523621 2.16 ENST00000325542.5
ENST00000325486.5
ENST00000544522.1
ENST00000541365.1
centrosomal protein 57kDa
chr7_-_26904317 2.16 ENST00000345317.2
src kinase associated phosphoprotein 2
chr2_+_238600933 2.15 ENST00000420665.1
ENST00000392000.4
leucine rich repeat (in FLII) interacting protein 1
chr3_+_40566369 2.14 ENST00000403205.2
ENST00000310898.1
ENST00000339296.5
ENST00000431278.1
zinc finger protein 621
chr11_+_114271251 2.12 ENST00000375490.5
RNA binding motif protein 7
chr1_-_95392635 2.12 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
calponin 3, acidic
chr2_-_9563575 2.11 ENST00000488451.1
ENST00000238091.4
ENST00000355346.4
integrin beta 1 binding protein 1
chrX_+_13707235 2.10 ENST00000464506.1
RAB9A, member RAS oncogene family
chr3_+_33155525 2.08 ENST00000449224.1
cartilage associated protein
chr20_+_5107532 2.04 ENST00000450570.1
ENST00000379062.4
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
chr3_+_134204551 2.04 ENST00000332047.5
ENST00000354446.3
centrosomal protein 63kDa
chr3_-_98241760 2.03 ENST00000507874.1
ENST00000502299.1
ENST00000508659.1
ENST00000510545.1
ENST00000511667.1
ENST00000394185.2
ENST00000394181.2
ENST00000508902.1
ENST00000341181.6
ENST00000437922.1
ENST00000394180.2
claudin domain containing 1
chrX_+_11776701 2.03 ENST00000476743.1
ENST00000421368.2
ENST00000398527.2
male-specific lethal 3 homolog (Drosophila)
chr3_-_146262428 2.03 ENST00000486631.1
phospholipid scramblase 1
chr11_+_114271314 2.03 ENST00000541475.1
RNA binding motif protein 7
chr12_-_102455846 2.02 ENST00000545679.1
coiled-coil domain containing 53
chr10_+_28822236 2.01 ENST00000347934.4
ENST00000354911.4
WW domain containing adaptor with coiled-coil
chr5_+_5422778 1.99 ENST00000296564.7
KIAA0947
chr8_+_33342268 1.99 ENST00000360128.6
MAK16 homolog (S. cerevisiae)
chr16_+_56642489 1.99 ENST00000561491.1
metallothionein 2A
chr8_-_131028660 1.97 ENST00000401979.2
ENST00000517654.1
ENST00000522361.1
ENST00000518167.1
family with sequence similarity 49, member B
chr3_-_182833863 1.93 ENST00000492597.1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr8_-_97273807 1.85 ENST00000517720.1
ENST00000287025.3
ENST00000523821.1
MTERF domain containing 1
chr1_-_200638964 1.85 ENST00000367348.3
ENST00000447706.2
ENST00000331314.6
DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
chr11_+_9482551 1.84 ENST00000438144.2
ENST00000526657.1
ENST00000299606.2
ENST00000534265.1
ENST00000412390.2
zinc finger protein 143
chr2_+_122494676 1.83 ENST00000455432.1
translin
chr7_-_134143841 1.82 ENST00000285930.4
aldo-keto reductase family 1, member B1 (aldose reductase)
chr2_-_9563319 1.82 ENST00000497105.1
ENST00000360635.3
ENST00000359712.3
integrin beta 1 binding protein 1
chrX_+_12993336 1.81 ENST00000380635.1
thymosin beta 4, X-linked
chr1_+_163039143 1.79 ENST00000531057.1
ENST00000527809.1
ENST00000367908.4
regulator of G-protein signaling 4
chr1_+_192778161 1.79 ENST00000235382.5
regulator of G-protein signaling 2, 24kDa
chr20_-_20033052 1.79 ENST00000536226.1
crooked neck pre-mRNA splicing factor 1
chr8_-_80942139 1.78 ENST00000521434.1
ENST00000519120.1
ENST00000520946.1
mitochondrial ribosomal protein S28
chr13_-_52703187 1.78 ENST00000355568.4
NIMA-related kinase 5
chr2_+_238600788 1.78 ENST00000289175.6
ENST00000244815.5
leucine rich repeat (in FLII) interacting protein 1
chrX_+_48433326 1.78 ENST00000376755.1
RNA binding motif (RNP1, RRM) protein 3
chr19_-_23941680 1.77 ENST00000402377.3
zinc finger protein 681
chr2_-_44588893 1.77 ENST00000409272.1
ENST00000410081.1
ENST00000541738.1
prolyl endopeptidase-like
chr7_+_64838786 1.77 ENST00000450302.2
zinc finger protein 92
chr2_-_55496174 1.76 ENST00000417363.1
ENST00000412530.1
ENST00000394600.3
ENST00000366137.2
ENST00000420637.1
mitochondrial translational initiation factor 2
chr3_+_54156570 1.76 ENST00000415676.2
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr12_-_99038732 1.75 ENST00000393042.3
ENST00000420861.1
ENST00000299157.4
ENST00000342502.2
IKBKB interacting protein
chr19_-_10445399 1.75 ENST00000592945.1
intercellular adhesion molecule 3
chr5_-_41870621 1.75 ENST00000196371.5
3-oxoacid CoA transferase 1
chr8_+_56792355 1.74 ENST00000519728.1
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr6_+_31465849 1.71 ENST00000399150.3
MHC class I polypeptide-related sequence B
chr4_+_77172847 1.71 ENST00000515604.1
ENST00000539752.1
ENST00000424749.2
uncharacterized protein LOC100631383
FAM47E-STBD1 readthrough
family with sequence similarity 47, member E
chr2_-_9563469 1.71 ENST00000484735.1
ENST00000456913.2
integrin beta 1 binding protein 1
chr7_+_56119323 1.70 ENST00000275603.4
ENST00000335503.3
ENST00000540286.1
chaperonin containing TCP1, subunit 6A (zeta 1)
chr1_+_111682827 1.69 ENST00000357172.4
choline/ethanolamine phosphotransferase 1
chr13_+_53029564 1.68 ENST00000468284.1
ENST00000378034.3
ENST00000258607.5
ENST00000378037.5
cytoskeleton associated protein 2
chr16_+_50776021 1.68 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
cylindromatosis (turban tumor syndrome)
chr6_+_86159765 1.66 ENST00000369646.3
ENST00000257770.3
5'-nucleotidase, ecto (CD73)
chr12_+_21654714 1.66 ENST00000542038.1
ENST00000540141.1
ENST00000229314.5
golgi transport 1B
chr2_-_69664549 1.66 ENST00000450796.2
ENST00000484177.1
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr10_+_5726764 1.65 ENST00000328090.5
ENST00000496681.1
family with sequence similarity 208, member B
chr13_-_31736478 1.65 ENST00000445273.2
heat shock 105kDa/110kDa protein 1
chr8_-_90996459 1.65 ENST00000517337.1
ENST00000409330.1
nibrin
chr11_-_65667997 1.65 ENST00000312562.2
ENST00000534222.1
FOS-like antigen 1
chr8_+_1922024 1.64 ENST00000320248.3
kelch repeat and BTB (POZ) domain containing 11
chr13_+_50070491 1.62 ENST00000496612.1
ENST00000357596.3
ENST00000485919.1
ENST00000442195.1
PHD finger protein 11
chr12_+_79258444 1.62 ENST00000261205.4
synaptotagmin I
chr3_+_54156664 1.61 ENST00000474759.1
ENST00000288197.5
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chrX_+_48432892 1.61 ENST00000376759.3
ENST00000430348.2
RNA binding motif (RNP1, RRM) protein 3
chr8_-_90996837 1.58 ENST00000519426.1
ENST00000265433.3
nibrin
chr10_+_28822636 1.58 ENST00000442148.1
ENST00000448193.1
WW domain containing adaptor with coiled-coil
chr4_+_57843876 1.58 ENST00000450656.1
ENST00000381227.1
polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
chr17_+_72462525 1.57 ENST00000360141.3
CD300a molecule
chr11_+_95523823 1.57 ENST00000538658.1
centrosomal protein 57kDa
chr8_+_117778736 1.57 ENST00000309822.2
ENST00000357148.3
ENST00000517814.1
ENST00000517820.1
UTP23, small subunit (SSU) processome component, homolog (yeast)
chr14_+_35591735 1.57 ENST00000604948.1
ENST00000605201.1
ENST00000250377.7
ENST00000321130.10
ENST00000534898.4
KIAA0391
chr4_-_186347099 1.55 ENST00000505357.1
ENST00000264689.6
UFM1-specific peptidase 2
chr10_+_11059826 1.55 ENST00000450189.1
CUGBP, Elav-like family member 2
chr19_+_35168633 1.54 ENST00000505365.2
zinc finger protein 302
chr8_-_101571933 1.53 ENST00000520311.1
ankyrin repeat domain 46
chr5_+_40679584 1.53 ENST00000302472.3
prostaglandin E receptor 4 (subtype EP4)
chr8_+_54793454 1.52 ENST00000276500.4
regulator of G-protein signaling 20
chr1_+_145516252 1.52 ENST00000369306.3
peroxisomal biogenesis factor 11 beta
chr4_+_71859156 1.52 ENST00000286648.5
ENST00000504730.1
ENST00000504952.1
deoxycytidine kinase
chr6_+_86159821 1.52 ENST00000369651.3
5'-nucleotidase, ecto (CD73)
chr5_-_57756087 1.52 ENST00000274289.3
polo-like kinase 2
chr7_+_89975979 1.51 ENST00000257659.8
ENST00000222511.6
ENST00000417207.1
GTP-binding protein 10 (putative)
chr13_-_52027134 1.51 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
integrator complex subunit 6
chr8_-_80942061 1.51 ENST00000519386.1
mitochondrial ribosomal protein S28
chr1_-_109584768 1.50 ENST00000357672.3
WD repeat domain 47
chr1_-_3816779 1.50 ENST00000361605.3
chromosome 1 open reading frame 174
chr4_+_113558612 1.50 ENST00000505034.1
ENST00000324052.6
La ribonucleoprotein domain family, member 7
chr13_-_36920615 1.49 ENST00000494062.2
spastic paraplegia 20 (Troyer syndrome)
chr16_+_31885079 1.49 ENST00000300870.10
ENST00000394846.3
zinc finger protein 267
chr4_-_69215467 1.49 ENST00000579690.1
YTH domain containing 1
chrX_+_12993202 1.48 ENST00000451311.2
ENST00000380636.1
thymosin beta 4, X-linked
chr9_+_72873837 1.48 ENST00000361138.5
structural maintenance of chromosomes 5
chr1_+_231664390 1.47 ENST00000366639.4
ENST00000413309.2
translin-associated factor X
chr2_-_86790593 1.47 ENST00000263856.4
ENST00000409225.2
charged multivesicular body protein 3
chr4_-_39367949 1.46 ENST00000503784.1
ENST00000349703.2
ENST00000381897.1
replication factor C (activator 1) 1, 145kDa
chr3_+_180630444 1.46 ENST00000491062.1
ENST00000468861.1
ENST00000445140.2
ENST00000484958.1
fragile X mental retardation, autosomal homolog 1
chr1_-_109584608 1.45 ENST00000400794.3
ENST00000528747.1
ENST00000369962.3
ENST00000361054.3
WD repeat domain 47
chr2_+_190526111 1.44 ENST00000607062.1
ENST00000260952.4
ENST00000425590.1
ENST00000607535.1
ENST00000420250.1
ENST00000606910.1
ENST00000607690.1
ENST00000607829.1
asparagine synthetase domain containing 1
chr5_-_86708670 1.44 ENST00000504878.1
cyclin H
chr2_-_38978492 1.43 ENST00000409276.1
ENST00000446327.2
ENST00000313117.6
serine/arginine-rich splicing factor 7
chr8_+_110552831 1.43 ENST00000530629.1
estrogen receptor binding site associated, antigen, 9
chr3_+_133292574 1.43 ENST00000264993.3
CDV3 homolog (mouse)
chr10_-_79397391 1.42 ENST00000286628.8
ENST00000406533.3
ENST00000354353.5
ENST00000404857.1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr15_+_52311398 1.42 ENST00000261845.5
mitogen-activated protein kinase 6
chr19_-_52097613 1.41 ENST00000301439.3
HCG2008157; Uncharacterized protein; cDNA FLJ30403 fis, clone BRACE2008480
chr3_-_189838670 1.41 ENST00000319332.5
leprecan-like 1
chr18_-_74701962 1.39 ENST00000585201.1
myelin basic protein
chr6_+_29691056 1.39 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
major histocompatibility complex, class I, F
chr8_-_80942467 1.38 ENST00000518271.1
ENST00000276585.4
ENST00000521605.1
mitochondrial ribosomal protein S28
chr6_+_29691198 1.38 ENST00000440587.2
ENST00000434407.2
major histocompatibility complex, class I, F
chr9_-_5437818 1.38 ENST00000223864.2
plasminogen receptor, C-terminal lysine transmembrane protein
chr8_-_101571964 1.37 ENST00000520552.1
ENST00000521345.1
ENST00000523000.1
ENST00000335659.3
ENST00000358990.3
ENST00000519597.1
ankyrin repeat domain 46
chr17_+_33895090 1.37 ENST00000592381.1
RP11-1094M14.11
chr10_-_17659357 1.37 ENST00000326961.6
ENST00000361271.3
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr13_-_36920872 1.37 ENST00000451493.1
spastic paraplegia 20 (Troyer syndrome)
chr3_+_37035263 1.36 ENST00000458205.2
ENST00000539477.1
mutL homolog 1
chr1_-_101491319 1.35 ENST00000342173.7
ENST00000488176.1
ENST00000370109.3
diphthamide biosynthesis 5
chr6_+_116692102 1.35 ENST00000359564.2
dermatan sulfate epimerase
chr12_-_50677255 1.35 ENST00000551691.1
ENST00000394943.3
ENST00000341247.4
LIM domain and actin binding 1
chr1_+_156163880 1.35 ENST00000359511.4
ENST00000423538.2
solute carrier family 25, member 44
chr4_-_156298028 1.35 ENST00000433024.1
ENST00000379248.2
microtubule-associated protein 9
chr3_-_121468513 1.33 ENST00000494517.1
ENST00000393667.3
golgin B1
chr12_+_54379569 1.33 ENST00000513209.1
RP11-834C11.12
chr2_-_86564776 1.32 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
receptor accessory protein 1
chr2_+_201981527 1.32 ENST00000441224.1
CASP8 and FADD-like apoptosis regulator
chr20_-_3748363 1.32 ENST00000217195.8
chromosome 20 open reading frame 27
chr22_-_19435755 1.31 ENST00000542103.1
ENST00000399562.4
chromosome 22 open reading frame 39
chr19_-_12512062 1.31 ENST00000595766.1
ENST00000430385.3
zinc finger protein 799
chr10_-_12084770 1.31 ENST00000357604.5
UPF2 regulator of nonsense transcripts homolog (yeast)
chr11_-_67374177 1.31 ENST00000333139.3
chromosome 11 open reading frame 72
chr6_+_36562132 1.30 ENST00000373715.6
ENST00000339436.7
serine/arginine-rich splicing factor 3
chr2_-_55496344 1.30 ENST00000403721.1
ENST00000263629.4
mitochondrial translational initiation factor 2
chr16_+_3115378 1.29 ENST00000529550.1
ENST00000551122.1
ENST00000525643.2
ENST00000548807.1
ENST00000528163.2
interleukin 32
chr1_+_109289279 1.29 ENST00000370008.3
syntaxin binding protein 3
chr14_+_58711539 1.29 ENST00000216455.4
ENST00000412908.2
ENST00000557508.1
proteasome (prosome, macropain) subunit, alpha type, 3
chr6_+_20403997 1.28 ENST00000535432.1
E2F transcription factor 3
chr11_-_22851367 1.28 ENST00000354193.4
small VCP/p97-interacting protein
chr14_+_51706886 1.28 ENST00000457354.2
thioredoxin-related transmembrane protein 1
chr17_+_57970469 1.28 ENST00000443572.2
ENST00000406116.3
ENST00000225577.4
ENST00000393021.3
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr2_-_234763147 1.28 ENST00000411486.2
ENST00000432087.1
ENST00000441687.1
ENST00000414924.1
Holliday junction recognition protein
chr15_+_75074410 1.27 ENST00000439220.2
c-src tyrosine kinase
chr14_+_93260642 1.27 ENST00000355976.2
golgin A5
chr18_+_20513278 1.26 ENST00000327155.5
retinoblastoma binding protein 8
chr3_+_44379611 1.26 ENST00000383746.3
ENST00000417237.1
T cell activation inhibitor, mitochondrial
chr12_+_72148614 1.26 ENST00000261263.3
RAB21, member RAS oncogene family

Network of associatons between targets according to the STRING database.

First level regulatory network of GMEB1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.6 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
1.5 4.6 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
1.3 7.8 GO:0098535 de novo centriole assembly(GO:0098535)
1.3 6.4 GO:0016476 regulation of embryonic cell shape(GO:0016476)
1.1 6.7 GO:0090646 mitochondrial tRNA processing(GO:0090646)
1.0 3.1 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
1.0 4.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
1.0 4.1 GO:0044375 regulation of peroxisome size(GO:0044375)
1.0 3.0 GO:0070668 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
1.0 2.9 GO:1990108 protein linear deubiquitination(GO:1990108)
1.0 3.9 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.9 3.7 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.9 2.7 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.9 2.7 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.9 2.6 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.8 3.2 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.7 0.7 GO:2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.7 2.1 GO:0051595 response to methylglyoxal(GO:0051595)
0.7 5.6 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.7 0.7 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.7 4.0 GO:0007296 vitellogenesis(GO:0007296)
0.6 3.8 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.6 7.6 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.6 1.9 GO:0051685 maintenance of ER location(GO:0051685)
0.6 1.9 GO:1904882 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.6 2.5 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.5 1.6 GO:0051300 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.5 3.9 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.5 4.8 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.5 3.3 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.5 2.8 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.5 1.4 GO:0051311 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.4 1.8 GO:0010165 response to X-ray(GO:0010165)
0.4 1.8 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.4 1.3 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.4 1.3 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.4 1.3 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.4 3.6 GO:0006552 leucine catabolic process(GO:0006552)
0.4 2.3 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.4 3.1 GO:0032790 ribosome disassembly(GO:0032790)
0.4 3.4 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.4 3.0 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.4 1.1 GO:0090520 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.4 0.7 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.4 1.1 GO:0031587 detection of endogenous stimulus(GO:0009726) positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.4 2.5 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.4 1.4 GO:0046833 snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
0.4 2.8 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.3 1.0 GO:0034093 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.3 1.7 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.3 1.0 GO:0072683 T cell extravasation(GO:0072683)
0.3 2.4 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.3 1.0 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.3 0.7 GO:1901026 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.3 2.0 GO:0035709 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.3 0.9 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.3 1.6 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.3 9.0 GO:0043968 histone H2A acetylation(GO:0043968)
0.3 3.1 GO:0032264 IMP salvage(GO:0032264)
0.3 0.6 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.3 1.8 GO:0010519 negative regulation of phospholipase activity(GO:0010519) regulation of adrenergic receptor signaling pathway(GO:0071877)
0.3 1.2 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.3 0.9 GO:0007518 myoblast fate determination(GO:0007518)
0.3 1.7 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.3 0.9 GO:0072709 cellular response to sorbitol(GO:0072709)
0.3 0.9 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.3 0.9 GO:1900158 negative regulation of osteoclast proliferation(GO:0090291) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.3 1.7 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.3 3.6 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.3 1.1 GO:0021564 vagus nerve development(GO:0021564)
0.3 1.4 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.3 2.8 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.3 0.8 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.3 0.8 GO:2000269 fibroblast apoptotic process(GO:0044346) regulation of fibroblast apoptotic process(GO:2000269) positive regulation of fibroblast apoptotic process(GO:2000271)
0.3 3.5 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.3 1.6 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.3 0.5 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) response to high density lipoprotein particle(GO:0055099)
0.3 0.8 GO:1990637 response to prolactin(GO:1990637)
0.3 1.3 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.3 0.8 GO:1900195 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
0.3 2.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.2 0.7 GO:1904693 midbrain morphogenesis(GO:1904693)
0.2 6.3 GO:0061157 mRNA destabilization(GO:0061157)
0.2 1.2 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.2 0.7 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220) cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250)
0.2 0.7 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.2 1.6 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.2 0.7 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.2 2.4 GO:0006657 CDP-choline pathway(GO:0006657)
0.2 0.9 GO:0016139 glycoside catabolic process(GO:0016139)
0.2 3.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 1.3 GO:0034976 response to endoplasmic reticulum stress(GO:0034976)
0.2 0.6 GO:0006404 RNA import into nucleus(GO:0006404)
0.2 0.6 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.2 0.2 GO:2000018 regulation of male gonad development(GO:2000018) positive regulation of male gonad development(GO:2000020)
0.2 1.0 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.2 1.7 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.2 0.6 GO:0031392 regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.2 1.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.2 0.6 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2 0.6 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.2 3.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.2 1.4 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.2 0.2 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.2 1.8 GO:0042182 ketone catabolic process(GO:0042182)
0.2 5.6 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.2 1.0 GO:0015862 uridine transport(GO:0015862)
0.2 0.6 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.2 1.5 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.2 0.5 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.2 4.7 GO:0034453 microtubule anchoring(GO:0034453)
0.2 1.8 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.2 1.1 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.2 1.6 GO:0046785 microtubule polymerization(GO:0046785)
0.2 0.9 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.2 1.4 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.2 2.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.2 1.9 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 1.7 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2 0.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 0.2 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491)
0.2 2.0 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.2 1.0 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.2 0.6 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.2 0.5 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.2 0.6 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.2 0.5 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.2 0.3 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.2 0.6 GO:0000103 sulfate assimilation(GO:0000103)
0.1 1.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.4 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.1 GO:0044843 G1/S transition of mitotic cell cycle(GO:0000082) cell cycle G1/S phase transition(GO:0044843)
0.1 0.7 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 0.4 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.1 5.7 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.1 0.7 GO:0035549 positive regulation of interferon-beta secretion(GO:0035549)
0.1 0.9 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.8 GO:0071233 cellular response to leucine(GO:0071233)
0.1 1.3 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.1 1.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.6 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.1 0.7 GO:1903911 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) positive regulation of postsynaptic membrane organization(GO:1901628) positive regulation of receptor clustering(GO:1903911)
0.1 0.7 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.1 0.4 GO:2000232 positive regulation of ribosome biogenesis(GO:0090070) regulation of rRNA processing(GO:2000232) positive regulation of rRNA processing(GO:2000234)
0.1 1.9 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.1 0.5 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.4 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 1.4 GO:0034465 response to carbon monoxide(GO:0034465)
0.1 0.8 GO:1990791 dorsal root ganglion development(GO:1990791)
0.1 1.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 2.3 GO:0016180 snRNA processing(GO:0016180)
0.1 1.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 1.8 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.1 0.8 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.1 0.5 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.4 GO:0006788 heme oxidation(GO:0006788)
0.1 5.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.5 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.1 0.9 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 0.5 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.1 1.3 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 3.1 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1 1.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.8 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 0.6 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 2.6 GO:0060148 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.1 0.2 GO:0051031 tRNA transport(GO:0051031)
0.1 0.5 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.5 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 1.1 GO:0009249 protein lipoylation(GO:0009249)
0.1 1.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 0.1 GO:0009838 abscission(GO:0009838)
0.1 0.2 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.3 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 0.4 GO:0046967 cytosol to ER transport(GO:0046967)
0.1 0.3 GO:0072402 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.1 0.9 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.7 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 1.6 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 0.6 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.8 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 2.6 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.4 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.7 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.2 GO:0032607 interferon-alpha production(GO:0032607)
0.1 2.4 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.1 0.4 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 0.5 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.1 1.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 1.5 GO:0043101 purine-containing compound salvage(GO:0043101)
0.1 0.4 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) regulation of melanosome transport(GO:1902908)
0.1 0.9 GO:0006983 ER overload response(GO:0006983)
0.1 0.4 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.1 0.2 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.1 1.2 GO:0008360 regulation of cell shape(GO:0008360)
0.1 0.4 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835) actin filament branching(GO:0090135)
0.1 0.6 GO:0015824 proline transport(GO:0015824)
0.1 0.6 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 1.7 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.2 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.1 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.4 GO:2001140 regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.1 0.9 GO:0044597 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.1 1.3 GO:0018345 protein palmitoylation(GO:0018345)
0.1 5.6 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.1 3.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 2.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.3 GO:0006014 D-ribose metabolic process(GO:0006014)
0.1 0.6 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 0.2 GO:1901376 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.1 2.0 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 1.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.4 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.1 0.2 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.1 1.0 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 0.8 GO:0032202 telomere assembly(GO:0032202)
0.1 0.6 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.1 0.7 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.1 2.7 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 0.9 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 0.7 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 0.2 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.1 0.2 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.1 0.3 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 2.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.7 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.7 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.2 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.1 0.6 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 0.3 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.1 0.3 GO:0043470 regulation of carbohydrate catabolic process(GO:0043470) regulation of cellular carbohydrate catabolic process(GO:0043471)
0.1 0.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.6 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.3 GO:0001895 retina homeostasis(GO:0001895)
0.1 0.2 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.6 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.8 GO:0006570 tyrosine metabolic process(GO:0006570)
0.1 0.6 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 0.4 GO:1901419 regulation of response to alcohol(GO:1901419)
0.1 0.9 GO:0021794 thalamus development(GO:0021794)
0.1 0.3 GO:0085020 protein K6-linked ubiquitination(GO:0085020) regulation of kinetochore assembly(GO:0090234)
0.1 0.3 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.1 0.4 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 3.3 GO:0006400 tRNA modification(GO:0006400)
0.1 0.3 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.2 GO:0035963 cellular response to interleukin-13(GO:0035963)
0.1 0.4 GO:0021978 telencephalon regionalization(GO:0021978)
0.1 0.6 GO:0042940 D-amino acid transport(GO:0042940)
0.1 1.5 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.3 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.1 0.7 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 0.5 GO:1905065 positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.1 0.2 GO:1903564 regulation of protein localization to cilium(GO:1903564)
0.1 0.3 GO:0003360 brainstem development(GO:0003360)
0.1 0.5 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.2 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.1 1.5 GO:0031114 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.1 0.5 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 0.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.9 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.2 GO:0060157 urinary bladder development(GO:0060157)
0.1 0.4 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.2 GO:0019086 late viral transcription(GO:0019086)
0.1 0.2 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 1.0 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.1 0.2 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.4 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 3.2 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.1 0.3 GO:0006953 acute-phase response(GO:0006953)
0.0 0.5 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.6 GO:0045116 protein neddylation(GO:0045116)
0.0 0.6 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.5 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.7 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 1.0 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.3 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.0 0.2 GO:0035811 negative regulation of urine volume(GO:0035811)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.4 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.7 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.2 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.5 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.0 GO:0071514 genetic imprinting(GO:0071514)
0.0 0.5 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.9 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 1.0 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 1.1 GO:0044458 motile cilium assembly(GO:0044458)
0.0 1.4 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.6 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0051944 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.5 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.0 2.8 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 0.4 GO:0006152 purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.0 0.3 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.3 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.5 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 1.5 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.2 GO:1902969 mitotic DNA replication(GO:1902969)
0.0 4.1 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.8 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 2.4 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835) negative regulation of protein depolymerization(GO:1901880)
0.0 0.7 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.0 0.8 GO:0045056 transcytosis(GO:0045056)
0.0 1.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0006415 translational termination(GO:0006415)
0.0 0.2 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.7 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.5 GO:0006295 nucleotide-excision repair, preincision complex stabilization(GO:0006293) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.2 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.0 0.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.4 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.6 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.3 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.6 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 1.4 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.0 0.6 GO:0070723 response to cholesterol(GO:0070723)
0.0 0.5 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 1.1 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.6 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.5 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692) cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 2.8 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.0 0.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.9 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 1.5 GO:0002223 innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.6 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 1.2 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 0.7 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.7 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.2 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 2.9 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.8 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 1.8 GO:0048278 vesicle docking(GO:0048278)
0.0 2.2 GO:0070125 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.0 0.1 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.9 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.1 GO:0009227 UDP-N-acetylglucosamine catabolic process(GO:0006049) nucleotide-sugar catabolic process(GO:0009227)
0.0 1.0 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.5 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.4 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.0 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.2 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.2 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0061386 soft palate development(GO:0060023) closure of optic fissure(GO:0061386)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.6 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 1.0 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.2 GO:0042723 thiamine-containing compound metabolic process(GO:0042723)
0.0 0.5 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.0 0.4 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.2 GO:0021860 positive regulation of neuroblast proliferation(GO:0002052) pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.3 GO:0006954 inflammatory response(GO:0006954)
0.0 0.8 GO:0032259 methylation(GO:0032259)
0.0 0.5 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.3 GO:0035329 hippo signaling(GO:0035329)
0.0 0.2 GO:0030323 respiratory tube development(GO:0030323) lung development(GO:0030324)
0.0 1.1 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.2 GO:0048793 pronephros development(GO:0048793)
0.0 0.4 GO:0008344 adult locomotory behavior(GO:0008344)
0.0 0.2 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.1 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 2.8 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.4 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.2 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.2 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.6 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.1 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0 0.1 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.3 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.1 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.0 0.4 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.7 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.5 GO:0098727 stem cell population maintenance(GO:0019827) maintenance of cell number(GO:0098727)
0.0 2.9 GO:0061337 cardiac conduction(GO:0061337)
0.0 0.4 GO:0051155 positive regulation of striated muscle cell differentiation(GO:0051155)
0.0 0.3 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.0 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.1 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.6 GO:0060964 regulation of gene silencing by miRNA(GO:0060964)
0.0 0.1 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.0 1.2 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.1 GO:0040008 regulation of growth(GO:0040008)
0.0 0.2 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.2 GO:0014904 myotube cell development(GO:0014904)
0.0 0.4 GO:0051017 actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.0 0.1 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.0 0.4 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 1.1 GO:0006302 double-strand break repair(GO:0006302)
0.0 0.1 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.1 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.0 0.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.5 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.0 0.5 GO:0007517 muscle organ development(GO:0007517)
0.0 0.3 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.3 GO:0097503 sialylation(GO:0097503)
0.0 0.0 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
0.0 0.1 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.2 GO:0003334 keratinocyte development(GO:0003334)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
1.3 6.7 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.9 2.6 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.7 3.6 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.6 3.1 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.6 4.2 GO:0030870 Mre11 complex(GO:0030870)
0.6 3.0 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.6 2.3 GO:0070985 TFIIK complex(GO:0070985)
0.5 4.4 GO:1990111 spermatoproteasome complex(GO:1990111)
0.5 1.6 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.5 1.6 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.5 3.9 GO:0070761 pre-snoRNP complex(GO:0070761)
0.5 6.4 GO:0097227 sperm annulus(GO:0097227)
0.5 1.4 GO:0005715 late recombination nodule(GO:0005715)
0.4 1.7 GO:1990423 RZZ complex(GO:1990423)
0.4 3.0 GO:0072487 MSL complex(GO:0072487)
0.4 1.3 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.4 3.3 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.4 1.2 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.4 1.1 GO:0043291 RAVE complex(GO:0043291)
0.4 1.5 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.4 1.4 GO:0005846 nuclear cap binding complex(GO:0005846)
0.3 4.0 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.3 1.2 GO:0000799 nuclear condensin complex(GO:0000799)
0.3 2.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.3 2.5 GO:0032039 integrator complex(GO:0032039)
0.3 1.6 GO:0032807 DNA ligase IV complex(GO:0032807)
0.3 2.9 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.3 2.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 6.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2 0.9 GO:0071001 U4/U6 snRNP(GO:0071001)
0.2 0.9 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.2 0.7 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.2 1.2 GO:0033263 CORVET complex(GO:0033263)
0.2 0.9 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.2 0.8 GO:0031417 NatC complex(GO:0031417)
0.2 2.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 0.6 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.2 1.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.2 1.4 GO:0033269 internode region of axon(GO:0033269)
0.2 0.6 GO:1990298 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.2 0.8 GO:0002177 manchette(GO:0002177)
0.2 2.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 1.7 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.2 3.4 GO:0097342 ripoptosome(GO:0097342)
0.2 0.5 GO:0005873 plus-end kinesin complex(GO:0005873)
0.2 0.7 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.2 1.7 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.2 0.7 GO:0097454 Schwann cell microvillus(GO:0097454)
0.2 0.5 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.2 0.7 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 2.0 GO:0044292 dendrite terminus(GO:0044292)
0.2 1.6 GO:0032156 septin cytoskeleton(GO:0032156)
0.2 0.2 GO:0005713 recombination nodule(GO:0005713)
0.2 1.1 GO:0071203 WASH complex(GO:0071203)
0.2 1.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.2 0.5 GO:0070195 growth hormone receptor complex(GO:0070195)
0.2 0.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 2.2 GO:0005869 dynactin complex(GO:0005869)
0.1 1.0 GO:0070852 cell body fiber(GO:0070852)
0.1 1.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 7.4 GO:0005844 polysome(GO:0005844)
0.1 1.4 GO:0072357 glycogen granule(GO:0042587) PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.4 GO:0034455 t-UTP complex(GO:0034455)
0.1 0.9 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.3 GO:0030689 Noc complex(GO:0030689)
0.1 0.6 GO:0097452 GAIT complex(GO:0097452)
0.1 0.9 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 2.1 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 1.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 1.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 2.3 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1 2.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.9 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1 2.8 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.5 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.6 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.8 GO:0070187 telosome(GO:0070187)
0.1 1.1 GO:0005614 interstitial matrix(GO:0005614)
0.1 4.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.6 GO:0005816 spindle pole body(GO:0005816)
0.1 2.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.6 GO:0042584 chromaffin granule membrane(GO:0042584) dendritic spine neck(GO:0044326)
0.1 1.0 GO:0005840 ribosome(GO:0005840)
0.1 1.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 7.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 9.5 GO:0005814 centriole(GO:0005814)
0.1 0.9 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.3 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 1.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.9 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.4 GO:0042824 MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.1 2.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 1.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.9 GO:0031209 SCAR complex(GO:0031209)
0.1 0.3 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 3.7 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 3.4 GO:0016235 aggresome(GO:0016235)
0.1 0.3 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 0.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 1.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 1.3 GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.7 GO:0000124 SAGA complex(GO:0000124)
0.1 0.3 GO:0030897 HOPS complex(GO:0030897)
0.1 0.5 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.4 GO:0000322 storage vacuole(GO:0000322)
0.1 0.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 1.2 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.6 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.2 GO:0000811 GINS complex(GO:0000811)
0.1 4.6 GO:0005811 lipid particle(GO:0005811)
0.1 0.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 1.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.1 GO:0090543 Flemming body(GO:0090543)
0.1 1.4 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.5 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 0.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.4 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.0 2.8 GO:0031201 SNARE complex(GO:0031201)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.4 GO:0030914 STAGA complex(GO:0030914)
0.0 1.4 GO:0032420 stereocilium(GO:0032420)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.5 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.8 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.8 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 1.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 3.9 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.2 GO:0038201 TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 3.0 GO:0030496 midbody(GO:0030496)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.4 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 4.7 GO:0042641 actomyosin(GO:0042641)
0.0 1.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.9 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0001939 female pronucleus(GO:0001939)
0.0 0.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 1.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 4.7 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 1.5 GO:0005813 centrosome(GO:0005813)
0.0 0.6 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 1.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 3.3 GO:0031091 platelet alpha granule(GO:0031091)
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 1.1 GO:0043235 receptor complex(GO:0043235)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.9 GO:0015030 Cajal body(GO:0015030)
0.0 0.4 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.1 GO:0005675 core TFIIH complex(GO:0000439) holo TFIIH complex(GO:0005675)
0.0 0.3 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.0 GO:0016234 inclusion body(GO:0016234)
0.0 5.1 GO:0005819 spindle(GO:0005819)
0.0 0.6 GO:0032040 small-subunit processome(GO:0032040)
0.0 8.3 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 1.0 GO:0045178 basal part of cell(GO:0045178)
0.0 0.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 4.0 GO:0005874 microtubule(GO:0005874)
0.0 1.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 2.6 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.3 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.3 GO:0043292 contractile fiber(GO:0043292)
0.0 0.2 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 1.6 GO:0030027 lamellipodium(GO:0030027)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.1 GO:0036317 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
1.5 4.6 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
1.2 3.5 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.8 2.4 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.8 2.4 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.7 3.6 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.6 8.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.6 2.5 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.5 2.7 GO:0030348 syntaxin-3 binding(GO:0030348)
0.5 3.2 GO:0046979 TAP2 binding(GO:0046979)
0.5 1.5 GO:0004137 deoxycytidine kinase activity(GO:0004137)
0.5 1.5 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.5 2.5 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.5 1.9 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.5 3.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.5 2.3 GO:0033592 RNA strand annealing activity(GO:0033592)
0.4 1.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.4 6.9 GO:0004526 ribonuclease P activity(GO:0004526)
0.4 3.0 GO:0043208 glycosphingolipid binding(GO:0043208)
0.4 1.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.4 1.1 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.3 2.0 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.3 1.3 GO:0030305 beta-glucuronidase activity(GO:0004566) heparanase activity(GO:0030305)
0.3 3.5 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.3 1.2 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.3 4.3 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.3 0.6 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.3 1.2 GO:0036033 mediator complex binding(GO:0036033)
0.3 1.2 GO:0004348 glucosylceramidase activity(GO:0004348)
0.3 0.9 GO:0005047 signal recognition particle binding(GO:0005047)
0.3 2.9 GO:1990380 Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
0.3 8.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.3 0.9 GO:0034046 poly(G) binding(GO:0034046)
0.3 1.1 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.3 0.9 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.3 1.1 GO:0048763 HLH domain binding(GO:0043398) calcium-induced calcium release activity(GO:0048763)
0.3 2.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3 0.8 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.3 0.8 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.2 1.7 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 0.9 GO:0008410 CoA-transferase activity(GO:0008410)
0.2 0.7 GO:0015616 DNA translocase activity(GO:0015616)
0.2 0.7 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.2 0.7 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.2 5.3 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.2 1.4 GO:0017018 myosin phosphatase activity(GO:0017018)
0.2 0.7 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.2 0.4 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2 1.3 GO:0039552 RIG-I binding(GO:0039552)
0.2 1.1 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.2 0.7 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.2 6.5 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 0.9 GO:0043515 kinetochore binding(GO:0043515)
0.2 2.9 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.2 1.7 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.2 1.0 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.2 2.3 GO:0043047 single-stranded telomeric DNA binding(GO:0043047)
0.2 0.6 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2 1.0 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 0.8 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.2 1.4 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.2 1.8 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.2 0.6 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.2 4.3 GO:0070402 NADPH binding(GO:0070402)
0.2 1.5 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.2 1.7 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.2 2.3 GO:0032407 MutSalpha complex binding(GO:0032407)
0.2 0.7 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.2 2.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 1.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.2 0.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.2 0.5 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.2 1.0 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.2 4.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 0.8 GO:0070728 leucine binding(GO:0070728)
0.2 0.7 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.2 1.0 GO:0034511 U3 snoRNA binding(GO:0034511)
0.2 1.8 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.2 0.7 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.2 0.7 GO:0004743 pyruvate kinase activity(GO:0004743)
0.2 1.0 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.2 0.8 GO:0070097 delta-catenin binding(GO:0070097)
0.2 0.9 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.2 0.9 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.2 2.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 0.6 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.2 4.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.4 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 2.3 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.7 GO:0002039 p53 binding(GO:0002039)
0.1 1.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 2.2 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 1.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.8 GO:0046870 cadmium ion binding(GO:0046870)
0.1 1.5 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 2.7 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 2.0 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 1.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 3.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.5 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1 3.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.4 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 0.6 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.4 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.8 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 0.9 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 8.2 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.9 GO:0016015 morphogen activity(GO:0016015)
0.1 0.4 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 0.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.3 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1 0.6 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 1.1 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 0.8 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 1.2 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 0.3 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 1.0 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 2.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 4.2 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.3 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.6 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 3.1 GO:0005123 death receptor binding(GO:0005123)
0.1 0.5 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.7 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.1 1.0 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 1.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 1.3 GO:0004875 complement receptor activity(GO:0004875)
0.1 2.9 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 2.3 GO:0031489 myosin V binding(GO:0031489)
0.1 0.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.4 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.1 1.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.6 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.1 0.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 5.1 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 2.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 7.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 0.3 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.1 1.7 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 1.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.8 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 2.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.6 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 1.0 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 5.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 1.0 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.9 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 1.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.5 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1 0.8 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 1.2 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1 0.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.3 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1 0.6 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.3 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.2 GO:0005148 prolactin receptor binding(GO:0005148)
0.1 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.1 0.6 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.8 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.5 GO:0019213 deacetylase activity(GO:0019213)
0.1 0.2 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 1.2 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.1 0.5 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 1.0 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 0.6 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.9 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 1.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 0.8 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.7 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 0.8 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.3 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 1.6 GO:0070035 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.1 0.2 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 1.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.5 GO:0046790 virion binding(GO:0046790)
0.1 1.6 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.1 1.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.5 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 1.4 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 1.1 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.7 GO:0005537 mannose binding(GO:0005537)
0.0 0.9 GO:0034212 peptide N-acetyltransferase activity(GO:0034212)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.0 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.7 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.0 0.3 GO:0050733 RS domain binding(GO:0050733)
0.0 0.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 1.4 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 1.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 1.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0035240 dopamine binding(GO:0035240)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 1.0 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.4 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.8 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0004645 phosphorylase activity(GO:0004645)
0.0 4.0 GO:0005262 calcium channel activity(GO:0005262)
0.0 1.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 1.1 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.2 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.6 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 1.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.9 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 1.1 GO:0004386 helicase activity(GO:0004386)
0.0 1.1 GO:0046332 SMAD binding(GO:0046332)
0.0 0.8 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.6 GO:0042171 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.6 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 1.6 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0019863 immunoglobulin receptor activity(GO:0019763) IgE binding(GO:0019863)
0.0 0.3 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 0.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 3.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.7 GO:0004519 endonuclease activity(GO:0004519)
0.0 0.4 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.3 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 1.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.4 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.0 4.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.8 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0016208 AMP binding(GO:0016208)
0.0 0.1 GO:0008948 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.0 0.6 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.1 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.3 GO:0000049 tRNA binding(GO:0000049)
0.0 0.2 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.0 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.0 0.2 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.5 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 3.5 GO:0008017 microtubule binding(GO:0008017)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.6 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 0.0 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 1.4 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 1.6 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.5 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 3.7 GO:0005525 GTP binding(GO:0005525)
0.0 0.3 GO:0043566 structure-specific DNA binding(GO:0043566)
0.0 0.3 GO:0016887 ATPase activity(GO:0016887)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.0 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 2.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)
0.0 0.3 GO:0050431 transforming growth factor beta binding(GO:0050431)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.9 PID CD40 PATHWAY CD40/CD40L signaling
0.1 5.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 5.2 PID BARD1 PATHWAY BARD1 signaling events
0.1 3.0 PID IL5 PATHWAY IL5-mediated signaling events
0.1 4.8 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 4.7 PID MYC PATHWAY C-MYC pathway
0.1 1.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 2.2 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.1 4.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.4 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 0.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 1.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 1.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 0.8 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 3.0 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 2.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 2.4 PID IL1 PATHWAY IL1-mediated signaling events
0.1 2.9 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 3.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 1.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 3.1 PID AURORA B PATHWAY Aurora B signaling
0.0 4.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.4 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.8 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.4 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.3 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 4.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.2 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.0 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.7 PID FGF PATHWAY FGF signaling pathway
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.3 PID ATM PATHWAY ATM pathway
0.0 0.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.4 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 PID ERBB4 PATHWAY ErbB4 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 1.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.3 3.9 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.3 2.8 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 6.6 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.2 4.1 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.2 1.9 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.2 4.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 2.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.2 3.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 4.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2 2.8 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 8.9 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 1.5 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 3.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 1.7 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 0.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 11.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 2.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 3.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 2.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 9.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 2.9 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 2.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 2.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 2.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 2.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 4.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 0.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 2.2 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.1 1.9 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.1 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 2.5 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.1 0.9 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.7 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 3.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.6 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.4 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 6.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.2 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 1.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 2.9 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 11.4 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 3.0 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.4 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.8 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.8 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 3.8 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 2.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 0.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.3 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.5 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 3.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.3 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 0.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.1 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.6 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism