Project

GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

Navigation
Downloads

Results for IRX3

Z-value: 1.22

Motif logo

Transcription factors associated with IRX3

Gene Symbol Gene ID Gene Info
ENSG00000177508.11 iroquois homeobox 3

Activity profile of IRX3 motif

Sorted Z-values of IRX3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_91574142 51.27 ENST00000547937.1
decorin
chr12_-_91573132 47.06 ENST00000550563.1
ENST00000546370.1
decorin
chr8_+_84824920 46.35 ENST00000523678.1
RP11-120I21.2
chr13_-_88323218 44.48 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
MIR4500 host gene (non-protein coding)
chr12_-_91573316 37.64 ENST00000393155.1
decorin
chr12_-_91546926 34.07 ENST00000550758.1
decorin
chr16_-_30032610 33.47 ENST00000574405.1
double C2-like domains, alpha
chr12_-_91573249 33.44 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
decorin
chr5_+_54320078 32.22 ENST00000231009.2
granzyme K (granzyme 3; tryptase II)
chr7_+_20686946 25.37 ENST00000443026.2
ENST00000406935.1
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr17_-_29641084 23.55 ENST00000544462.1
ecotropic viral integration site 2B
chr14_-_21945057 23.11 ENST00000397762.1
RAB2B, member RAS oncogene family
chr9_-_116102530 22.99 ENST00000374195.3
ENST00000341761.4
WD repeat domain 31
chr2_-_89545079 22.42 ENST00000468494.1
immunoglobulin kappa variable 2-30
chr11_+_57365150 22.37 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr12_-_9268707 22.06 ENST00000318602.7
alpha-2-macroglobulin
chr2_-_136875712 21.74 ENST00000241393.3
chemokine (C-X-C motif) receptor 4
chr4_+_106631966 20.91 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
glutathione S-transferase, C-terminal domain containing
chr9_+_105757590 20.86 ENST00000374798.3
ENST00000487798.1
cylicin, basic protein of sperm head cytoskeleton 2
chr3_-_122283100 20.27 ENST00000492382.1
ENST00000462315.1
poly (ADP-ribose) polymerase family, member 9
chr10_-_90712520 19.85 ENST00000224784.6
actin, alpha 2, smooth muscle, aorta
chr11_-_111782696 19.84 ENST00000227251.3
ENST00000526180.1
crystallin, alpha B
chr7_-_150020578 19.81 ENST00000478393.1
ARP3 actin-related protein 3 homolog C (yeast)
chr9_-_116102562 19.74 ENST00000374193.4
ENST00000465979.1
WD repeat domain 31
chr2_+_89975669 19.28 ENST00000474213.1
immunoglobulin kappa variable 2D-30
chr1_+_46668994 18.62 ENST00000371980.3
leucine rich adaptor protein 1
chr16_-_75498553 18.40 ENST00000569276.1
ENST00000357613.4
ENST00000561878.1
ENST00000566980.1
ENST00000567194.1
transmembrane protein 170A
Uncharacterized protein
chr19_+_9296279 17.86 ENST00000344248.2
olfactory receptor, family 7, subfamily D, member 2
chr4_-_186125077 17.81 ENST00000458385.2
ENST00000514798.1
ENST00000296775.6
KIAA1430
chr12_-_71182695 17.74 ENST00000342084.4
protein tyrosine phosphatase, receptor type, R
chr1_+_26644441 17.71 ENST00000374213.2
CD52 molecule
chr6_-_52705641 17.69 ENST00000370989.2
glutathione S-transferase alpha 5
chr2_+_111490161 17.19 ENST00000340561.4
acyl-CoA oxidase-like
chr11_-_5255861 15.92 ENST00000380299.3
hemoglobin, delta
chr1_+_117297007 15.71 ENST00000369478.3
ENST00000369477.1
CD2 molecule
chr6_-_49834209 15.67 ENST00000507853.1
cysteine-rich secretory protein 1
chr11_+_61891445 15.37 ENST00000394818.3
ENST00000533896.1
ENST00000278849.4
inner centromere protein antigens 135/155kDa
chr1_+_158259558 15.28 ENST00000368170.3
CD1c molecule
chr17_-_18585541 15.02 ENST00000285274.5
ENST00000545289.1
ENST00000580145.1
zinc finger protein 286B
chr12_+_10365404 14.79 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABA(A) receptor-associated protein like 1
chr4_+_88754069 14.73 ENST00000395102.4
ENST00000497649.2
matrix extracellular phosphoglycoprotein
chr3_+_122044084 14.66 ENST00000264474.3
ENST00000479204.1
cystatin A (stefin A)
chr2_+_90139056 14.64 ENST00000492446.1
immunoglobulin kappa variable 1D-16
chr5_-_177207634 14.60 ENST00000513554.1
ENST00000440605.3
family with sequence similarity 153, member A
chr1_-_153029980 14.55 ENST00000392653.2
small proline-rich protein 2A
chr17_-_29641104 14.39 ENST00000577894.1
ENST00000330927.4
ecotropic viral integration site 2B
chr12_+_133757995 14.06 ENST00000536435.2
ENST00000228289.5
ENST00000541211.2
ENST00000500625.3
ENST00000539248.2
ENST00000542711.2
ENST00000536899.2
ENST00000542986.2
ENST00000537565.1
ENST00000541975.2
zinc finger protein 268
chr12_-_10251603 14.05 ENST00000457018.2
C-type lectin domain family 1, member A
chr15_+_66585555 13.62 ENST00000319194.5
ENST00000525134.2
ENST00000441424.2
DIS3 mitotic control homolog (S. cerevisiae)-like
chr3_-_48936272 13.57 ENST00000544097.1
ENST00000430379.1
ENST00000319017.4
solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
chr1_+_22964073 13.52 ENST00000402322.1
complement component 1, q subcomponent, A chain
chr1_+_196788887 13.43 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
complement factor H-related 1
complement factor H-related 2
chr6_-_49834240 13.12 ENST00000335847.4
cysteine-rich secretory protein 1
chr12_+_21679220 13.09 ENST00000256969.2
chromosome 12 open reading frame 39
chr7_+_40174565 12.88 ENST00000309930.5
ENST00000401647.2
ENST00000335693.4
ENST00000413931.1
ENST00000416370.1
ENST00000540834.1
succinylCoA:glutarate-CoA transferase
chr1_+_52870227 12.77 ENST00000257181.9
pre-mRNA processing factor 38A
chr1_+_202317815 12.49 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
protein phosphatase 1, regulatory subunit 12B
chr2_-_196933536 12.48 ENST00000312428.6
ENST00000410072.1
dynein, axonemal, heavy chain 7
chrX_+_153639856 12.10 ENST00000426834.1
ENST00000369790.4
ENST00000454722.1
ENST00000350743.4
ENST00000299328.5
ENST00000351413.4
tafazzin
chr6_+_127587755 12.01 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
ring finger protein 146
chr20_+_54933971 11.87 ENST00000371384.3
ENST00000437418.1
family with sequence similarity 210, member B
chr11_-_118213331 11.78 ENST00000392884.2
CD3d molecule, delta (CD3-TCR complex)
chr13_+_97928395 11.76 ENST00000445661.2
muscleblind-like splicing regulator 2
chr2_+_189839046 11.70 ENST00000304636.3
ENST00000317840.5
collagen, type III, alpha 1
chr17_-_47755338 11.69 ENST00000508805.1
ENST00000515508.2
ENST00000451526.2
ENST00000507970.1
speckle-type POZ protein
chr12_+_32655048 11.57 ENST00000427716.2
ENST00000266482.3
FYVE, RhoGEF and PH domain containing 4
chr16_+_67840668 11.53 ENST00000415766.3
translin-associated factor X interacting protein 1
chr11_-_111782484 11.48 ENST00000533971.1
crystallin, alpha B
chr8_+_12803176 11.46 ENST00000524591.2
KIAA1456
chr14_+_95047725 11.37 ENST00000554760.1
ENST00000554866.1
ENST00000329597.7
ENST00000556775.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr14_+_95047744 11.04 ENST00000553511.1
ENST00000554633.1
ENST00000555681.1
ENST00000554276.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr7_+_55086703 10.98 ENST00000455089.1
ENST00000342916.3
ENST00000344576.2
ENST00000420316.2
epidermal growth factor receptor
chrX_+_15767971 10.94 ENST00000479740.1
ENST00000454127.2
carbonic anhydrase VB, mitochondrial
chr11_-_118213455 10.83 ENST00000300692.4
CD3d molecule, delta (CD3-TCR complex)
chr5_+_147443534 10.81 ENST00000398454.1
ENST00000359874.3
ENST00000508733.1
ENST00000256084.7
serine peptidase inhibitor, Kazal type 5
chr1_+_22778337 10.74 ENST00000404138.1
ENST00000400239.2
ENST00000375647.4
ENST00000374651.4
zinc finger and BTB domain containing 40
chr2_+_113816215 10.73 ENST00000346807.3
interleukin 36 receptor antagonist
chr3_+_171561127 10.73 ENST00000334567.5
ENST00000450693.1
transmembrane protein 212
chr8_+_27631903 10.62 ENST00000305188.8
establishment of sister chromatid cohesion N-acetyltransferase 2
chr16_+_31539197 10.51 ENST00000564707.1
alpha hemoglobin stabilizing protein
chr12_-_10542617 10.44 ENST00000240618.6
killer cell lectin-like receptor subfamily K, member 1
chr22_+_51176624 10.40 ENST00000216139.5
ENST00000529621.1
acrosin
chr19_-_40919271 10.39 ENST00000291825.7
ENST00000324001.7
periaxin
chr4_-_80329356 10.37 ENST00000358842.3
glycerol kinase 2
chr10_-_103815874 10.32 ENST00000370033.4
ENST00000311122.5
chromosome 10 open reading frame 76
chr12_+_69742121 10.26 ENST00000261267.2
ENST00000549690.1
ENST00000548839.1
lysozyme
chr14_-_106926724 10.11 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr3_+_53528659 10.09 ENST00000350061.5
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr12_-_95467267 10.04 ENST00000330677.7
nuclear receptor subfamily 2, group C, member 1
chr2_+_90121477 10.02 ENST00000483379.1
immunoglobulin kappa variable 1D-17
chr11_-_35547572 9.94 ENST00000378880.2
peptidase domain containing associated with muscle regeneration 1
chr13_+_25338290 9.89 ENST00000255324.5
ENST00000381921.1
ENST00000255325.6
ring finger protein 17
chr3_-_183543301 9.80 ENST00000318631.3
ENST00000431348.1
MAP6 domain containing 1
chr3_+_8543533 9.72 ENST00000454244.1
LIM and cysteine-rich domains 1
chr12_-_66524482 9.48 ENST00000446587.2
ENST00000266604.2
LLP homolog, long-term synaptic facilitation (Aplysia)
chr3_+_138066539 9.42 ENST00000289104.4
muscle RAS oncogene homolog
chrX_-_140673133 9.36 ENST00000370519.3
sperm protein associated with the nucleus, X-linked, family member A1
chr19_+_55281260 9.25 ENST00000336077.6
ENST00000291633.7
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
chr5_+_175490540 9.16 ENST00000515817.1
family with sequence similarity 153, member B
chr11_+_60739115 9.14 ENST00000344028.5
ENST00000346437.4
CD6 molecule
chr11_+_111783450 9.12 ENST00000537382.1
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr16_+_48657361 9.09 ENST00000565072.1
RP11-42I10.1
chr20_-_18477862 9.07 ENST00000337227.4
retinoblastoma binding protein 9
chr11_+_89764274 8.96 ENST00000448984.1
ENST00000432771.1
tripartite motif containing 49C
chr11_+_111782934 8.95 ENST00000304298.3
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr19_+_55591743 8.92 ENST00000588359.1
ENST00000245618.5
EPS8-like 1
chr3_+_186383741 8.82 ENST00000232003.4
histidine-rich glycoprotein
chr14_+_22386325 8.81 ENST00000390439.2
T cell receptor alpha variable 13-2
chr12_-_9360966 8.73 ENST00000261336.2
pregnancy-zone protein
chr1_-_23504176 8.72 ENST00000302291.4
leucine zipper protein 1
chrX_+_76709648 8.62 ENST00000439435.1
fibroblast growth factor 16
chr17_-_34207295 8.55 ENST00000463941.1
ENST00000293272.3
chemokine (C-C motif) ligand 5
chr1_+_196912902 8.50 ENST00000476712.2
ENST00000367415.5
complement factor H-related 2
chr12_-_10007448 8.46 ENST00000538152.1
C-type lectin domain family 2, member B
chr2_-_89459813 8.35 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr14_-_107131560 8.29 ENST00000390632.2
immunoglobulin heavy variable 3-66
chr11_+_113258495 8.24 ENST00000303941.3
ankyrin repeat and kinase domain containing 1
chr10_+_13628933 8.20 ENST00000417658.1
ENST00000320054.4
pre-mRNA processing factor 18
chr13_+_53226963 8.19 ENST00000343788.6
ENST00000535397.1
ENST00000310528.8
SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
chr15_-_51630772 8.15 ENST00000557858.1
ENST00000558328.1
ENST00000396404.4
ENST00000561075.1
ENST00000405011.2
ENST00000559980.1
ENST00000453807.2
ENST00000396402.1
cytochrome P450, family 19, subfamily A, polypeptide 1
chr15_+_25200074 8.11 ENST00000390687.4
ENST00000584968.1
ENST00000346403.6
ENST00000554227.2
small nuclear ribonucleoprotein polypeptide N
chr2_-_242041607 8.09 ENST00000434791.1
ENST00000401626.2
ENST00000439144.1
ENST00000406593.1
ENST00000495694.1
ENST00000407095.3
ENST00000391980.2
MTERF domain containing 2
chr1_+_158985457 8.09 ENST00000567661.1
ENST00000474473.1
interferon, gamma-inducible protein 16
chr1_-_52870104 8.08 ENST00000371568.3
origin recognition complex, subunit 1
chr16_+_33204156 8.06 ENST00000398667.4
TP53 target 3C
chr15_-_83680325 8.06 ENST00000508990.2
ENST00000510873.2
ENST00000538348.2
ENST00000451195.3
ENST00000513601.2
ENST00000304177.5
ENST00000565712.1
chromosome 15 open reading frame 40
chr12_-_11422739 7.94 ENST00000279573.7
proline-rich protein BstNI subfamily 3
chr16_+_67840986 7.94 ENST00000561639.1
ENST00000567852.1
ENST00000565148.1
ENST00000388833.3
ENST00000561654.1
ENST00000431934.2
translin-associated factor X interacting protein 1
chr19_-_45004556 7.88 ENST00000587047.1
ENST00000391956.4
ENST00000221327.4
ENST00000586637.1
ENST00000591064.1
ENST00000592529.1
zinc finger protein 180
chr19_-_52531600 7.88 ENST00000356322.6
ENST00000270649.6
zinc finger protein 614
chr1_-_7913089 7.83 ENST00000361696.5
urotensin 2
chr5_-_95297678 7.79 ENST00000237853.4
elongation factor, RNA polymerase II, 2
chr1_-_16302565 7.78 ENST00000537142.1
ENST00000448462.2
zinc finger and BTB domain containing 17
chr11_-_47870091 7.75 ENST00000526870.1
nucleoporin 160kDa
chr15_-_56757329 7.73 ENST00000260453.3
meiosis-specific nuclear structural 1
chr5_+_54455946 7.71 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
glutathione peroxidase 8 (putative)
chr14_-_106692191 7.70 ENST00000390607.2
immunoglobulin heavy variable 3-21
chr2_-_201729284 7.58 ENST00000434813.2
CDC-like kinase 1
chr2_-_16804320 7.57 ENST00000355549.2
family with sequence similarity 49, member A
chr13_+_96085847 7.57 ENST00000376873.3
claudin 10
chr6_+_26204825 7.55 ENST00000360441.4
histone cluster 1, H4e
chr1_+_196857144 7.48 ENST00000367416.2
ENST00000251424.4
ENST00000367418.2
complement factor H-related 4
chr2_+_85921414 7.47 ENST00000263863.4
ENST00000524600.1
granulysin
chr1_+_53308398 7.43 ENST00000371528.1
zyg-11 family member A, cell cycle regulator
chrX_+_83116142 7.39 ENST00000329312.4
cylicin, basic protein of sperm head cytoskeleton 1
chr1_+_44584522 7.30 ENST00000372299.3
Kruppel-like factor 17
chr16_+_84209539 7.28 ENST00000569735.1
dynein, axonemal, assembly factor 1
chr22_+_23161491 7.23 ENST00000390316.2
immunoglobulin lambda variable 3-9 (gene/pseudogene)
chr5_-_93447333 7.23 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
family with sequence similarity 172, member A
chr4_+_75023816 7.21 ENST00000395759.2
ENST00000331145.6
ENST00000359107.5
ENST00000325278.6
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
chr20_-_44600810 7.21 ENST00000322927.2
ENST00000426788.1
zinc finger protein 335
chr2_+_85921522 7.21 ENST00000409696.3
granulysin
chr2_-_201936302 7.18 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
family with sequence similarity 126, member B
chr15_-_81616446 7.08 ENST00000302824.6
StAR-related lipid transfer (START) domain containing 5
chr22_-_36556821 7.06 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
apolipoprotein L, 3
chr2_-_89521942 7.06 ENST00000482769.1
immunoglobulin kappa variable 2-28
chr11_+_114166536 7.05 ENST00000299964.3
nicotinamide N-methyltransferase
chrX_-_6453159 7.03 ENST00000381089.3
ENST00000398729.1
variable charge, X-linked 3A
chr12_+_106751436 6.99 ENST00000228347.4
polymerase (RNA) III (DNA directed) polypeptide B
chr19_+_55327923 6.94 ENST00000391728.4
ENST00000326542.7
ENST00000358178.4
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
chr18_-_28622774 6.93 ENST00000434452.1
desmocollin 3
chr9_-_100684845 6.93 ENST00000375119.3
chromosome 9 open reading frame 156
chr2_-_152589670 6.89 ENST00000604864.1
ENST00000603639.1
nebulin
chr16_+_1578674 6.85 ENST00000253934.5
transmembrane protein 204
chr12_+_9102632 6.82 ENST00000539240.1
killer cell lectin-like receptor subfamily G, member 1
chr1_+_152975488 6.81 ENST00000542696.1
small proline-rich protein 3
chr10_+_60272814 6.80 ENST00000373886.3
bicaudal C homolog 1 (Drosophila)
chr11_+_60739140 6.78 ENST00000313421.7
CD6 molecule
chr3_-_149470229 6.73 ENST00000473414.1
COMM domain containing 2
chr22_+_23154239 6.68 ENST00000390315.2
immunoglobulin lambda variable 3-10
chrX_+_150866779 6.68 ENST00000370353.3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr7_-_38289173 6.67 ENST00000436911.2
T cell receptor gamma constant 2
chr5_-_59481406 6.64 ENST00000546160.1
phosphodiesterase 4D, cAMP-specific
chr17_+_34431212 6.64 ENST00000394495.1
chemokine (C-C motif) ligand 4
chr14_-_106963409 6.64 ENST00000390621.2
immunoglobulin heavy variable 1-45
chr11_-_49230184 6.63 ENST00000340334.7
ENST00000256999.2
folate hydrolase (prostate-specific membrane antigen) 1
chr4_+_70146217 6.62 ENST00000335568.5
ENST00000511240.1
UDP glucuronosyltransferase 2 family, polypeptide B28
chr7_-_99573640 6.62 ENST00000411734.1
alpha-2-glycoprotein 1, zinc-binding
chr7_-_4901625 6.59 ENST00000404991.1
poly(A) polymerase beta (testis specific)
chr1_+_160709029 6.50 ENST00000444090.2
ENST00000441662.2
SLAM family member 7
chr4_-_141348999 6.46 ENST00000325617.5
calmegin
chr17_+_34430980 6.46 ENST00000250151.4
chemokine (C-C motif) ligand 4
chr11_+_60739249 6.43 ENST00000542157.1
ENST00000433107.2
ENST00000452451.2
ENST00000352009.5
CD6 molecule
chr5_-_115872142 6.39 ENST00000510263.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr15_-_22473353 6.38 ENST00000557788.2
immunoglobulin heavy variable 4/OR15-8 (non-functional)
chr2_-_127963343 6.38 ENST00000335247.7
cytochrome P450, family 27, subfamily C, polypeptide 1
chr11_-_118305921 6.37 ENST00000532619.1
RP11-770J1.4
chr11_-_118213360 6.36 ENST00000529594.1
CD3d molecule, delta (CD3-TCR complex)
chr9_-_95298314 6.34 ENST00000344604.5
ENST00000375540.1
extracellular matrix protein 2, female organ and adipocyte specific
chr2_-_99771373 6.34 ENST00000393483.3
testis specific, 10
chr22_-_29457832 6.33 ENST00000216071.4
chromosome 22 open reading frame 31
chr17_+_18380051 6.32 ENST00000581545.1
ENST00000582333.1
ENST00000328114.6
ENST00000412421.2
ENST00000583322.1
ENST00000584941.1
lectin, galactoside-binding, soluble, 9C
chr22_+_40297105 6.31 ENST00000540310.1
GRB2-related adaptor protein 2
chr1_+_215747118 6.28 ENST00000448333.1
potassium channel tetramerization domain containing 3
chr8_+_120885949 6.22 ENST00000523492.1
ENST00000286234.5
DEP domain containing MTOR-interacting protein
chr12_-_10282836 6.18 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
C-type lectin domain family 7, member A
chr4_+_71600144 6.18 ENST00000502653.1
RUN and FYVE domain containing 3
chr21_+_41239243 6.15 ENST00000328619.5
Purkinje cell protein 4
chr11_-_85376121 6.12 ENST00000527447.1
CREB/ATF bZIP transcription factor
chr11_-_104480019 6.10 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
17.7 212.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
6.3 25.4 GO:0048749 compound eye development(GO:0048749)
5.9 17.6 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
4.9 14.7 GO:0002818 intracellular defense response(GO:0002818)
4.5 22.4 GO:0061107 seminal vesicle development(GO:0061107)
3.7 11.0 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
3.6 32.1 GO:2000501 regulation of natural killer cell chemotaxis(GO:2000501)
3.4 44.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
3.4 20.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
3.3 19.9 GO:0090131 mesenchyme migration(GO:0090131)
3.1 21.7 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
3.0 12.1 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
3.0 17.7 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
2.8 19.3 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
2.7 8.2 GO:2000861 negative regulation of macrophage chemotaxis(GO:0010760) estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
2.7 10.8 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
2.6 10.4 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
2.5 5.0 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
2.2 29.0 GO:0045059 positive thymic T cell selection(GO:0045059)
2.2 28.8 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
2.1 6.3 GO:0009107 lipoate biosynthetic process(GO:0009107)
2.1 10.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
2.0 5.9 GO:1903487 regulation of lactation(GO:1903487)
2.0 7.8 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
2.0 5.9 GO:0042113 B cell activation(GO:0042113)
1.8 14.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
1.8 19.8 GO:0036159 inner dynein arm assembly(GO:0036159)
1.8 10.7 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
1.8 25.0 GO:0045919 positive regulation of cytolysis(GO:0045919)
1.8 5.3 GO:1990523 bone regeneration(GO:1990523)
1.7 31.3 GO:0007021 tubulin complex assembly(GO:0007021)
1.7 6.9 GO:0007525 somatic muscle development(GO:0007525)
1.7 25.6 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
1.7 9.9 GO:0016554 cytidine to uridine editing(GO:0016554)
1.6 3.3 GO:0050916 sensory perception of sweet taste(GO:0050916)
1.6 6.4 GO:0032053 ciliary basal body organization(GO:0032053)
1.6 4.8 GO:1903935 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
1.5 9.3 GO:0002765 immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
1.5 4.5 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
1.5 10.4 GO:0007341 penetration of zona pellucida(GO:0007341)
1.5 5.9 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
1.5 8.8 GO:0052422 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
1.5 23.4 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
1.4 2.9 GO:1904468 negative regulation of tumor necrosis factor secretion(GO:1904468)
1.4 7.2 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
1.4 10.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
1.4 5.7 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
1.4 9.8 GO:0006498 N-terminal protein lipidation(GO:0006498)
1.4 2.8 GO:1900005 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
1.3 5.4 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
1.3 4.0 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
1.3 11.8 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
1.3 15.3 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
1.3 11.5 GO:0002098 tRNA wobble uridine modification(GO:0002098)
1.3 3.8 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
1.3 3.8 GO:0019605 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
1.2 18.6 GO:0015671 oxygen transport(GO:0015671)
1.2 8.6 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
1.2 3.6 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
1.2 4.6 GO:0005986 sucrose biosynthetic process(GO:0005986)
1.2 4.6 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
1.1 18.4 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
1.1 6.6 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
1.1 10.5 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
1.0 71.4 GO:0006910 phagocytosis, recognition(GO:0006910)
1.0 3.1 GO:0006711 estrogen catabolic process(GO:0006711)
1.0 16.5 GO:0042574 retinal metabolic process(GO:0042574)
1.0 4.1 GO:0010966 regulation of phosphate transport(GO:0010966)
1.0 7.1 GO:0035376 sterol import(GO:0035376) cholesterol import(GO:0070508)
1.0 22.2 GO:0030502 negative regulation of bone mineralization(GO:0030502) negative regulation of biomineral tissue development(GO:0070168)
1.0 5.0 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
1.0 4.0 GO:0003095 pressure natriuresis(GO:0003095)
1.0 6.0 GO:0048241 epinephrine transport(GO:0048241)
1.0 93.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.9 2.7 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.9 44.5 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.9 14.8 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.9 3.5 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.9 5.1 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
0.8 5.9 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.8 32.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.8 3.3 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.8 3.2 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.8 5.5 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.8 7.6 GO:0018210 peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210)
0.8 2.3 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.7 3.7 GO:0030035 microspike assembly(GO:0030035)
0.7 3.7 GO:0008210 estrogen metabolic process(GO:0008210)
0.7 6.6 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.7 5.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.7 8.7 GO:0001842 neural fold formation(GO:0001842)
0.7 4.1 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.7 5.4 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.6 3.2 GO:0033504 floor plate development(GO:0033504)
0.6 7.0 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.6 5.1 GO:0070995 NADPH oxidation(GO:0070995)
0.6 3.8 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.6 12.7 GO:0006853 carnitine shuttle(GO:0006853)
0.6 10.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.6 1.2 GO:0002434 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264)
0.6 11.4 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.6 4.8 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.6 7.7 GO:0070986 left/right axis specification(GO:0070986)
0.6 2.4 GO:0002329 pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.6 8.9 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.6 15.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.6 1.7 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.6 2.9 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.6 5.7 GO:0006069 ethanol oxidation(GO:0006069)
0.6 10.3 GO:0042572 retinol metabolic process(GO:0042572)
0.6 5.7 GO:0060174 limb bud formation(GO:0060174)
0.6 1.7 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.6 5.7 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.6 6.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.6 4.4 GO:0016139 glycoside catabolic process(GO:0016139)
0.5 2.2 GO:0030242 pexophagy(GO:0030242)
0.5 2.2 GO:0071221 response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.5 2.7 GO:0099590 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967) neurotransmitter receptor internalization(GO:0099590)
0.5 3.7 GO:0051597 response to methylmercury(GO:0051597)
0.5 4.7 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.5 13.5 GO:0071168 protein localization to chromatin(GO:0071168)
0.5 7.2 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.5 2.5 GO:0030070 insulin processing(GO:0030070)
0.5 9.6 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.5 16.6 GO:0045730 respiratory burst(GO:0045730)
0.5 13.5 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.5 2.5 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.5 1.5 GO:0071048 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.5 10.4 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.5 2.8 GO:0002278 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.5 4.7 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.5 12.6 GO:0097484 dendrite extension(GO:0097484)
0.5 3.2 GO:0098704 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.5 3.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.5 19.8 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.4 2.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.4 20.0 GO:0018149 peptide cross-linking(GO:0018149)
0.4 2.2 GO:0044241 lipid digestion(GO:0044241)
0.4 1.7 GO:2000232 regulation of ribosome biogenesis(GO:0090069) regulation of rRNA processing(GO:2000232)
0.4 5.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.4 2.5 GO:0003228 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.4 2.0 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.4 1.6 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276) chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.4 1.2 GO:0006063 uronic acid metabolic process(GO:0006063) glucuronate metabolic process(GO:0019585) cellular glucuronidation(GO:0052695)
0.4 3.9 GO:1904424 regulation of GTP binding(GO:1904424)
0.4 1.2 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.4 3.8 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.4 1.5 GO:1900003 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.4 4.1 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.4 4.5 GO:0048194 Golgi vesicle budding(GO:0048194)
0.4 1.5 GO:0035425 autocrine signaling(GO:0035425)
0.4 3.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.4 4.0 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.4 7.2 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.4 22.0 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.3 4.9 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455)
0.3 13.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.3 1.4 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.3 4.1 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)
0.3 2.4 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.3 3.0 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.3 1.0 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.3 16.3 GO:0006730 one-carbon metabolic process(GO:0006730)
0.3 10.5 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.3 2.6 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.3 2.6 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.3 1.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.3 6.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.3 3.7 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.3 5.8 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.3 5.0 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.3 7.4 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.3 3.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.3 4.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.3 41.0 GO:0002377 immunoglobulin production(GO:0002377)
0.3 8.4 GO:0050710 negative regulation of cytokine secretion(GO:0050710)
0.3 2.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.3 2.7 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.3 7.5 GO:0030449 regulation of complement activation(GO:0030449)
0.3 20.7 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.3 7.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.3 1.6 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.3 2.0 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.2 2.2 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.2 0.5 GO:0032499 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499)
0.2 4.3 GO:0003334 keratinocyte development(GO:0003334)
0.2 1.6 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.2 5.8 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.2 6.8 GO:0001945 lymph vessel development(GO:0001945)
0.2 18.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2 2.0 GO:0097186 amelogenesis(GO:0097186)
0.2 5.0 GO:0010390 histone monoubiquitination(GO:0010390)
0.2 12.0 GO:0051865 protein autoubiquitination(GO:0051865)
0.2 5.5 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.2 3.9 GO:0034505 tooth mineralization(GO:0034505)
0.2 4.6 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.2 5.0 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.2 2.2 GO:0060539 diaphragm development(GO:0060539)
0.2 1.6 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.2 1.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2 7.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 4.3 GO:0043277 apoptotic cell clearance(GO:0043277)
0.2 1.9 GO:0036120 negative regulation of fibroblast migration(GO:0010764) response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.2 5.6 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.2 17.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.2 5.5 GO:0097120 receptor localization to synapse(GO:0097120)
0.2 16.3 GO:0070268 cornification(GO:0070268)
0.2 8.9 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.2 1.7 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.2 12.1 GO:0046847 filopodium assembly(GO:0046847)
0.2 1.8 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.2 4.0 GO:0009235 cobalamin metabolic process(GO:0009235)
0.2 2.7 GO:0006020 inositol metabolic process(GO:0006020)
0.2 1.4 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.2 18.2 GO:0048232 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.2 3.9 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 2.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 2.4 GO:0001502 cartilage condensation(GO:0001502)
0.1 7.1 GO:0001895 retina homeostasis(GO:0001895)
0.1 3.2 GO:0030488 tRNA methylation(GO:0030488)
0.1 4.9 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 4.3 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.1 3.2 GO:0002092 positive regulation of receptor internalization(GO:0002092)
0.1 0.4 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 0.7 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005) cellular response to norepinephrine stimulus(GO:0071874)
0.1 1.0 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.1 3.5 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 2.7 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 2.1 GO:0005513 detection of calcium ion(GO:0005513)
0.1 4.3 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.1 0.6 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1 2.1 GO:0035810 positive regulation of urine volume(GO:0035810)
0.1 0.5 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 2.9 GO:0043243 positive regulation of protein complex disassembly(GO:0043243)
0.1 10.0 GO:0016575 histone deacetylation(GO:0016575)
0.1 7.8 GO:0030282 bone mineralization(GO:0030282)
0.1 2.0 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.3 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.9 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 1.7 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
0.1 7.7 GO:0098869 cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 11.6 GO:0016925 protein sumoylation(GO:0016925)
0.1 2.5 GO:0035640 exploration behavior(GO:0035640)
0.1 0.8 GO:1903358 regulation of Golgi organization(GO:1903358)
0.1 1.4 GO:0042100 B cell proliferation(GO:0042100)
0.1 9.9 GO:0007286 spermatid development(GO:0007286)
0.1 13.4 GO:0006937 regulation of muscle contraction(GO:0006937)
0.1 1.2 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 2.8 GO:0007601 visual perception(GO:0007601) sensory perception of light stimulus(GO:0050953)
0.1 5.0 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 1.6 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.1 0.5 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 4.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 4.4 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.1 0.8 GO:0090311 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) regulation of protein deacetylation(GO:0090311)
0.1 0.5 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 2.9 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.1 1.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 8.9 GO:0008366 ensheathment of neurons(GO:0007272) axon ensheathment(GO:0008366)
0.1 1.1 GO:0050890 cognition(GO:0050890)
0.1 2.4 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.8 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.9 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 4.3 GO:0045814 negative regulation of gene expression, epigenetic(GO:0045814)
0.1 1.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 2.5 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.1 2.1 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.1 0.2 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.1 0.8 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 2.1 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.1 2.5 GO:0031175 neuron projection development(GO:0031175)
0.1 1.1 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.1 1.6 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.6 GO:0043691 reverse cholesterol transport(GO:0043691)
0.0 6.9 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.5 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 3.4 GO:0006094 gluconeogenesis(GO:0006094)
0.0 0.7 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.0 0.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.9 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 1.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.7 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 10.7 GO:0045666 positive regulation of neuron differentiation(GO:0045666)
0.0 1.5 GO:0045576 mast cell activation(GO:0045576)
0.0 2.1 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 1.0 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 2.4 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.7 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.9 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 2.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 2.0 GO:0007270 neuron-neuron synaptic transmission(GO:0007270)
0.0 0.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 1.1 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 3.6 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 1.7 GO:0008360 regulation of cell shape(GO:0008360)
0.0 1.2 GO:0050680 negative regulation of epithelial cell proliferation(GO:0050680)
0.0 0.6 GO:0006968 cellular defense response(GO:0006968)
0.0 0.4 GO:0019933 cAMP-mediated signaling(GO:0019933)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
14.5 203.5 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
9.4 28.2 GO:0033011 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
7.5 22.4 GO:0097182 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
5.2 10.4 GO:0043159 acrosomal matrix(GO:0043159)
5.0 19.9 GO:0030485 smooth muscle contractile fiber(GO:0030485)
3.7 11.0 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
3.3 9.9 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
3.1 15.4 GO:0000801 central element(GO:0000801)
2.7 13.5 GO:0005602 complement component C1 complex(GO:0005602)
2.6 29.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
2.5 35.7 GO:0005833 hemoglobin complex(GO:0005833)
2.4 9.6 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
2.1 14.7 GO:0097013 phagocytic vesicle lumen(GO:0097013)
2.0 31.3 GO:0097512 cardiac myofibril(GO:0097512)
1.8 5.3 GO:0000806 Y chromosome(GO:0000806)
1.5 10.8 GO:0097209 epidermal lamellar body(GO:0097209)
1.4 5.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
1.1 57.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
1.1 12.7 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
1.1 13.7 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
1.0 19.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.9 4.7 GO:0070847 core mediator complex(GO:0070847)
0.9 2.7 GO:0097679 other organism cytoplasm(GO:0097679)
0.9 12.5 GO:0005858 axonemal dynein complex(GO:0005858)
0.8 10.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.8 10.6 GO:0001741 XY body(GO:0001741) nuclear pericentric heterochromatin(GO:0031618)
0.7 2.2 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.7 2.9 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.7 12.8 GO:0071011 precatalytic spliceosome(GO:0071011)
0.7 14.8 GO:0042101 T cell receptor complex(GO:0042101)
0.7 11.8 GO:0005687 U4 snRNP(GO:0005687)
0.6 2.5 GO:0030314 junctional membrane complex(GO:0030314)
0.6 12.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.6 18.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.6 31.4 GO:0001533 cornified envelope(GO:0001533)
0.6 0.6 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.5 3.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.5 92.4 GO:0072562 blood microparticle(GO:0072562)
0.5 4.6 GO:0061574 ASAP complex(GO:0061574)
0.5 5.5 GO:0060077 inhibitory synapse(GO:0060077)
0.5 3.9 GO:0000322 storage vacuole(GO:0000322)
0.5 1.5 GO:0071020 post-spliceosomal complex(GO:0071020)
0.5 7.8 GO:0031080 nuclear pore outer ring(GO:0031080)
0.5 15.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.5 3.2 GO:0031415 NatA complex(GO:0031415)
0.4 5.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.4 3.4 GO:0034464 BBSome(GO:0034464)
0.4 1.4 GO:0016939 kinesin II complex(GO:0016939)
0.3 8.6 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.3 28.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.3 5.0 GO:0036020 endolysosome membrane(GO:0036020)
0.3 4.0 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.3 6.0 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.3 1.5 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.3 11.5 GO:0030018 Z disc(GO:0030018)
0.3 2.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.3 1.9 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.3 4.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.3 1.6 GO:0045179 apical cortex(GO:0045179)
0.3 4.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.2 2.1 GO:0005883 neurofilament(GO:0005883)
0.2 1.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 4.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 7.8 GO:0002102 podosome(GO:0002102)
0.2 29.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.2 15.1 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.2 1.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 5.0 GO:0071437 invadopodium(GO:0071437)
0.2 2.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 21.5 GO:0042641 actomyosin(GO:0042641)
0.2 22.4 GO:0031225 anchored component of membrane(GO:0031225)
0.2 3.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 9.8 GO:0005801 cis-Golgi network(GO:0005801)
0.2 1.6 GO:0016013 syntrophin complex(GO:0016013)
0.2 8.7 GO:0031672 A band(GO:0031672)
0.2 227.4 GO:0005615 extracellular space(GO:0005615)
0.2 24.2 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 5.7 GO:0000786 nucleosome(GO:0000786)
0.1 12.6 GO:0035097 histone methyltransferase complex(GO:0035097)
0.1 7.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 2.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 4.3 GO:0005581 collagen trimer(GO:0005581)
0.1 3.2 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 4.6 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 1.2 GO:0033391 chromatoid body(GO:0033391)
0.1 9.6 GO:0030175 filopodium(GO:0030175)
0.1 7.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 4.0 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.1 3.5 GO:0045095 keratin filament(GO:0045095)
0.1 2.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 13.8 GO:0009986 cell surface(GO:0009986)
0.1 13.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 2.2 GO:0032587 ruffle membrane(GO:0032587)
0.1 5.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 10.4 GO:0016324 apical plasma membrane(GO:0016324)
0.1 11.1 GO:0042383 sarcolemma(GO:0042383)
0.1 1.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 6.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 6.3 GO:0031514 motile cilium(GO:0031514)
0.1 1.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.1 2.8 GO:0016459 myosin complex(GO:0016459)
0.1 3.8 GO:0005884 actin filament(GO:0005884)
0.1 1.5 GO:0001772 immunological synapse(GO:0001772)
0.0 5.7 GO:0001650 fibrillar center(GO:0001650)
0.0 52.9 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 2.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 26.0 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.8 GO:0005938 cell cortex(GO:0005938)
0.0 0.8 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 1.5 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.5 GO:0016234 inclusion body(GO:0016234)
0.0 1.1 GO:0030027 lamellipodium(GO:0030027)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.4 22.1 GO:0019959 interleukin-8 binding(GO:0019959)
6.3 6.3 GO:0070052 collagen V binding(GO:0070052)
4.5 13.6 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
4.2 20.9 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
3.6 25.4 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
3.5 10.4 GO:0004040 amidase activity(GO:0004040) fucose binding(GO:0042806)
3.3 22.8 GO:0070891 lipoteichoic acid binding(GO:0070891)
3.1 21.7 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
2.9 14.7 GO:1990430 extracellular matrix protein binding(GO:1990430)
2.9 14.5 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
2.7 196.8 GO:0050840 extracellular matrix binding(GO:0050840)
2.6 7.9 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
2.5 15.1 GO:0030492 hemoglobin binding(GO:0030492)
2.4 12.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
2.4 21.7 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
2.4 7.2 GO:0004487 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
2.4 9.6 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
2.3 20.9 GO:0032190 acrosin binding(GO:0032190)
2.3 11.5 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
2.2 11.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
2.1 10.6 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
2.1 6.3 GO:0016992 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
2.0 6.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
2.0 6.0 GO:0008513 secondary active organic cation transmembrane transporter activity(GO:0008513)
1.8 5.5 GO:0004917 interleukin-7 receptor activity(GO:0004917)
1.8 3.6 GO:0048030 disaccharide binding(GO:0048030)
1.8 5.3 GO:0046848 hydroxyapatite binding(GO:0046848)
1.8 7.0 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
1.7 10.4 GO:0015057 thrombin receptor activity(GO:0015057)
1.7 10.3 GO:0003796 lysozyme activity(GO:0003796)
1.7 18.6 GO:0005344 oxygen transporter activity(GO:0005344)
1.7 6.6 GO:1904492 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
1.6 6.4 GO:0005502 11-cis retinal binding(GO:0005502)
1.6 4.8 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
1.6 4.7 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
1.5 15.3 GO:0030882 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
1.4 4.2 GO:0019961 interferon binding(GO:0019961)
1.3 4.0 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
1.2 17.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
1.2 3.6 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) uptake transmembrane transporter activity(GO:0015563)
1.2 5.9 GO:0031708 endothelin B receptor binding(GO:0031708)
1.2 4.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
1.2 6.9 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
1.2 4.6 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
1.2 4.6 GO:0004657 proline dehydrogenase activity(GO:0004657)
1.1 4.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
1.1 14.8 GO:0030957 Tat protein binding(GO:0030957)
1.0 57.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
1.0 5.1 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
1.0 4.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
1.0 31.3 GO:0005212 structural constituent of eye lens(GO:0005212)
1.0 4.0 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
1.0 3.9 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
1.0 16.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
1.0 5.7 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.9 10.1 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.9 10.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.9 2.7 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.9 44.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.9 3.4 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.8 20.3 GO:0070403 NAD+ binding(GO:0070403)
0.8 5.0 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.8 2.5 GO:0017129 triglyceride binding(GO:0017129)
0.8 3.2 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.8 10.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.7 8.9 GO:0042608 T cell receptor binding(GO:0042608)
0.7 2.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662) Toll-like receptor 2 binding(GO:0035663)
0.7 125.1 GO:0003823 antigen binding(GO:0003823)
0.7 9.9 GO:0070330 aromatase activity(GO:0070330)
0.7 18.3 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.7 36.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.7 12.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.7 3.3 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.7 5.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.7 17.7 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.7 3.9 GO:0017018 myosin phosphatase activity(GO:0017018)
0.7 7.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.6 1.9 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.6 3.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.6 1.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.6 3.0 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.6 1.7 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.6 4.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.6 2.8 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.6 3.9 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.5 2.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.5 1.6 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.5 8.6 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.5 2.7 GO:0061665 SUMO ligase activity(GO:0061665)
0.5 4.8 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.5 54.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.5 2.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.5 7.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.5 8.7 GO:0032052 bile acid binding(GO:0032052)
0.5 1.5 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.5 2.0 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.5 1.5 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.5 2.4 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.5 3.2 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.5 13.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.4 2.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.4 11.9 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701)
0.4 2.2 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.4 1.2 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.4 4.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.4 11.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.4 3.8 GO:0009374 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.4 4.1 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.4 18.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.4 1.8 GO:0004771 sterol esterase activity(GO:0004771)
0.4 2.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.3 4.5 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 6.6 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.3 4.9 GO:0015245 fatty acid transporter activity(GO:0015245) very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.3 1.4 GO:0004979 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.3 1.7 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.3 2.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.3 4.3 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.3 3.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.3 25.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.3 5.6 GO:0070840 dynein complex binding(GO:0070840)
0.3 3.9 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.3 0.6 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.3 6.8 GO:0042288 MHC class I protein binding(GO:0042288)
0.3 14.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.3 7.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 1.6 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.3 56.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.3 4.1 GO:0005522 profilin binding(GO:0005522)
0.3 2.0 GO:1990932 5.8S rRNA binding(GO:1990932)
0.3 1.0 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.2 1.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.2 23.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 3.7 GO:0044548 S100 protein binding(GO:0044548)
0.2 2.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 1.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 0.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 4.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.2 5.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 0.6 GO:0033149 FFAT motif binding(GO:0033149)
0.2 10.0 GO:0033558 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.2 6.1 GO:0070063 RNA polymerase binding(GO:0070063)
0.2 31.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 7.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 1.0 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.2 5.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 1.5 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 2.7 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.2 6.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 3.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.2 9.3 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.2 0.9 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.2 7.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 27.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 13.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 2.2 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.2 0.5 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 2.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 1.9 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 9.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 3.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 3.1 GO:0005319 lipid transporter activity(GO:0005319)
0.1 5.6 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.1 2.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 3.3 GO:0042169 SH2 domain binding(GO:0042169)
0.1 6.0 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 1.7 GO:0005217 intracellular ligand-gated ion channel activity(GO:0005217) calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1 1.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.9 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 2.2 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 5.9 GO:0051018 protein kinase A binding(GO:0051018)
0.1 3.7 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.8 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.5 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.6 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 5.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 2.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 7.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 2.2 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.1 1.0 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 1.8 GO:0001848 complement binding(GO:0001848)
0.1 1.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.1 GO:0015643 toxic substance binding(GO:0015643)
0.1 16.3 GO:0030674 protein binding, bridging(GO:0030674)
0.1 10.3 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.1 4.4 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.1 6.4 GO:0019210 kinase inhibitor activity(GO:0019210)
0.1 2.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 2.4 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 0.9 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 4.9 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 1.4 GO:0030507 spectrin binding(GO:0030507)
0.1 14.2 GO:0030246 carbohydrate binding(GO:0030246)
0.1 2.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 1.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 1.8 GO:0004519 endonuclease activity(GO:0004519)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 4.7 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.7 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 28.7 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 2.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 3.2 GO:0005179 hormone activity(GO:0005179)
0.0 2.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 5.7 GO:0042393 histone binding(GO:0042393)
0.0 1.2 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 0.4 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 3.5 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.4 GO:0030552 cAMP binding(GO:0030552)
0.0 1.5 GO:0019838 growth factor binding(GO:0019838)
0.0 3.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 207.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.8 0.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.6 9.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.6 10.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.6 21.7 PID S1P S1P3 PATHWAY S1P3 pathway
0.5 133.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.5 26.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.5 11.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.4 10.3 PID CONE PATHWAY Visual signal transduction: Cones
0.4 2.7 ST JAK STAT PATHWAY Jak-STAT Pathway
0.4 11.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.4 21.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.4 63.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.4 6.5 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.3 18.0 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.3 4.4 PID IL5 PATHWAY IL5-mediated signaling events
0.3 4.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 10.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.2 4.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.2 5.6 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.2 10.8 PID MYC PATHWAY C-MYC pathway
0.2 10.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.2 2.5 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.2 1.1 PID IL27 PATHWAY IL27-mediated signaling events
0.2 6.5 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.2 17.0 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.2 3.1 ST GA12 PATHWAY G alpha 12 Pathway
0.2 3.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.2 14.9 PID CMYB PATHWAY C-MYB transcription factor network
0.2 5.9 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.2 7.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.2 5.1 PID ENDOTHELIN PATHWAY Endothelins
0.1 2.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 4.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 3.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 15.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 13.7 PID E2F PATHWAY E2F transcription factor network
0.1 14.2 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 6.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 7.4 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 10.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 4.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 1.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 2.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 5.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 2.4 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 1.9 PID RAS PATHWAY Regulation of Ras family activation
0.1 6.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 2.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 2.4 PID FGF PATHWAY FGF signaling pathway
0.1 0.6 PID IL23 PATHWAY IL23-mediated signaling events
0.1 16.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 2.9 PID LKB1 PATHWAY LKB1 signaling events
0.1 3.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.2 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 2.1 PID BMP PATHWAY BMP receptor signaling
0.0 1.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.2 PID AURORA A PATHWAY Aurora A signaling
0.0 5.8 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 0.5 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
7.5 203.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
4.3 21.7 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
2.2 44.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
1.3 29.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
1.2 13.5 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
1.1 13.7 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
1.1 16.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.9 11.7 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.9 44.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.7 8.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.6 23.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.5 17.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.5 21.0 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.5 13.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.5 15.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.5 8.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.4 9.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.4 11.4 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.4 5.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.4 12.7 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.4 23.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.4 24.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.4 8.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.3 26.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.3 10.4 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.3 5.1 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.3 17.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.3 12.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.2 13.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.2 12.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 4.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 11.7 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.2 3.8 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 2.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 7.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 4.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.2 9.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.2 6.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 11.8 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.2 2.4 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.2 1.8 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 4.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 15.0 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.2 5.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 6.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 2.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 3.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 15.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 8.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 2.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 4.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 5.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 2.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 9.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 2.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 3.6 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 2.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.9 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 4.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 3.9 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.1 12.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 1.0 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 4.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 2.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 2.2 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.1 9.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 29.3 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.1 2.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 2.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 2.1 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 2.0 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 3.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 2.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 1.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 7.5 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 3.0 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 2.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 2.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 3.6 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 1.0 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 2.2 REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse