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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for KLF3

Z-value: 0.31

Motif logo

Transcription factors associated with KLF3

Gene Symbol Gene ID Gene Info
ENSG00000109787.8 Kruppel like factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF3hg19_v2_chr4_+_38665810_386658270.228.5e-04Click!

Activity profile of KLF3 motif

Sorted Z-values of KLF3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_72432950 11.64 ENST00000426523.1
ENST00000429686.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr19_-_10464570 8.01 ENST00000529739.1
tyrosine kinase 2
chrX_-_71526741 7.04 ENST00000454225.1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr6_-_35109080 6.92 ENST00000486638.1
ENST00000505400.1
ENST00000412155.2
ENST00000373979.2
ENST00000507706.1
ENST00000444780.2
ENST00000492680.2
t-complex 11, testis-specific
chr6_-_33048483 6.49 ENST00000419277.1
major histocompatibility complex, class II, DP alpha 1
chr16_-_11370330 6.40 ENST00000241808.4
ENST00000435245.2
protamine 2
chr6_-_32498046 6.30 ENST00000374975.3
major histocompatibility complex, class II, DR beta 5
chr19_+_49838653 6.18 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37 molecule
chr11_+_117857063 6.18 ENST00000227752.3
ENST00000541785.1
ENST00000545409.1
interleukin 10 receptor, alpha
chr1_-_160681593 6.06 ENST00000368045.3
ENST00000368046.3
CD48 molecule
chr2_+_71295733 5.70 ENST00000443938.2
ENST00000244204.6
N-acetylglucosamine kinase
chr20_+_30639991 5.65 ENST00000534862.1
ENST00000538448.1
ENST00000375862.2
hemopoietic cell kinase
chr19_+_1067271 5.37 ENST00000536472.1
ENST00000590214.1
histocompatibility (minor) HA-1
chr2_+_71295717 5.27 ENST00000418807.3
ENST00000443872.2
N-acetylglucosamine kinase
chrX_-_71526813 5.22 ENST00000246139.5
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr19_-_13213662 5.19 ENST00000264824.4
lymphoblastic leukemia derived sequence 1
chrX_-_71526999 5.15 ENST00000453707.2
ENST00000373619.3
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr9_+_100174344 5.09 ENST00000422139.2
tudor domain containing 7
chr17_+_42427826 5.08 ENST00000586443.1
granulin
chr16_-_68033356 5.01 ENST00000393847.1
ENST00000573808.1
ENST00000572624.1
dipeptidase 2
chr7_-_150497621 4.99 ENST00000434545.1
transmembrane protein 176B
chr12_-_13256593 4.94 ENST00000542415.1
ENST00000324458.8
germ cell associated 1
chr11_-_5248294 4.88 ENST00000335295.4
hemoglobin, beta
chr22_-_51017084 4.88 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
carnitine palmitoyltransferase 1B (muscle)
chrX_-_52260199 4.84 ENST00000375600.1
X antigen family, member 1A
chr6_+_144471643 4.84 ENST00000367568.4
syntaxin 11
chr20_+_55966444 4.84 ENST00000356208.5
ENST00000440234.2
RNA binding motif protein 38
chrX_+_52511925 4.71 ENST00000375588.1
X antigen family, member 1C
chr11_-_64512273 4.70 ENST00000377497.3
ENST00000377487.1
ENST00000430645.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr17_+_33914460 4.68 ENST00000537622.2
adaptor-related protein complex 2, beta 1 subunit
chr5_-_149492904 4.66 ENST00000286301.3
ENST00000511344.1
colony stimulating factor 1 receptor
chr16_+_1578674 4.65 ENST00000253934.5
transmembrane protein 204
chr7_+_73623717 4.63 ENST00000344995.5
ENST00000460943.1
linker for activation of T cells family, member 2
chr12_+_111843749 4.62 ENST00000341259.2
SH2B adaptor protein 3
chrX_-_52533139 4.61 ENST00000374959.3
X antigen family, member 1D
chr12_-_13256571 4.58 ENST00000545401.1
ENST00000432710.2
ENST00000351606.6
germ cell associated 1
chr19_+_14492247 4.42 ENST00000357355.3
ENST00000592261.2
ENST00000242786.5
CD97 molecule
chr17_-_76870126 4.41 ENST00000586057.1
TIMP metallopeptidase inhibitor 2
chr6_-_35109145 4.39 ENST00000373974.4
ENST00000244645.3
t-complex 11, testis-specific
chr11_+_121447469 4.36 ENST00000532694.1
ENST00000534286.1
sortilin-related receptor, L(DLR class) A repeats containing
chr2_+_37571717 4.33 ENST00000338415.3
ENST00000404976.1
glutaminyl-peptide cyclotransferase
chr1_+_2004901 4.20 ENST00000400921.2
protein kinase C, zeta
chrX_-_47489244 4.17 ENST00000469388.1
ENST00000396992.3
ENST00000377005.2
complement factor properdin
chr17_+_33914276 4.14 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
adaptor-related protein complex 2, beta 1 subunit
chr4_-_90757364 4.12 ENST00000508895.1
synuclein, alpha (non A4 component of amyloid precursor)
chr17_-_26876350 4.05 ENST00000470125.1
unc-119 homolog (C. elegans)
chr7_+_150497569 4.03 ENST00000004103.3
transmembrane protein 176A
chr19_-_4455290 4.03 ENST00000394765.3
ENST00000592515.1
UBX domain protein 6
chr2_+_37571845 4.02 ENST00000537448.1
glutaminyl-peptide cyclotransferase
chrX_-_52546033 4.00 ENST00000375567.3
X antigen family, member 1E
chr10_-_73611046 3.82 ENST00000394934.1
ENST00000394936.3
prosaposin
chr7_-_150498426 3.72 ENST00000447204.2
transmembrane protein 176B
chr19_+_36195467 3.71 ENST00000426659.2
zinc finger and BTB domain containing 32
chr22_-_51016846 3.71 ENST00000312108.7
ENST00000395650.2
carnitine palmitoyltransferase 1B (muscle)
chr7_-_2272566 3.66 ENST00000402746.1
ENST00000265854.7
ENST00000429779.1
ENST00000399654.2
MAD1 mitotic arrest deficient-like 1 (yeast)
chr7_+_150434430 3.57 ENST00000358647.3
GTPase, IMAP family member 5
chr5_-_176433693 3.57 ENST00000507513.1
ENST00000511320.1
ubiquitin interaction motif containing 1
chr11_-_2906979 3.53 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr7_+_150497491 3.52 ENST00000484928.1
transmembrane protein 176A
chr19_+_12902289 3.47 ENST00000302754.4
jun B proto-oncogene
chr5_-_176433582 3.41 ENST00000506128.1
ubiquitin interaction motif containing 1
chr17_+_7452336 3.37 ENST00000293826.4
TNFSF12-TNFSF13 readthrough
chr16_+_85061367 3.36 ENST00000538274.1
ENST00000258180.3
KIAA0513
chr11_-_64511575 3.36 ENST00000431822.1
ENST00000377486.3
ENST00000394432.3
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr22_-_50964558 3.34 ENST00000535425.1
ENST00000439934.1
SCO2 cytochrome c oxidase assembly protein
chr19_-_10450328 3.28 ENST00000160262.5
intercellular adhesion molecule 3
chr1_+_38022572 3.23 ENST00000541606.1
dynein, axonemal, light intermediate chain 1
chr22_-_26961328 3.22 ENST00000398110.2
tyrosylprotein sulfotransferase 2
chr8_+_22436635 3.20 ENST00000452226.1
ENST00000397760.4
ENST00000339162.7
ENST00000397761.2
PDZ and LIM domain 2 (mystique)
chr5_-_150521192 3.17 ENST00000523714.1
ENST00000521749.1
annexin A6
chr11_-_5531215 3.16 ENST00000311659.4
ubiquilin 3
chr19_-_10450287 3.15 ENST00000589261.1
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
intercellular adhesion molecule 3
chr19_+_1941117 3.15 ENST00000255641.8
casein kinase 1, gamma 2
chr3_-_49449350 3.15 ENST00000454011.2
ENST00000445425.1
ENST00000422781.1
ras homolog family member A
chr8_-_134115118 3.14 ENST00000395352.3
ENST00000338087.5
Src-like-adaptor
chr12_+_116997186 3.13 ENST00000306985.4
microtubule-associated protein 1 light chain 3 beta 2
chr11_-_64512803 3.08 ENST00000377489.1
ENST00000354024.3
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr3_+_186648307 3.02 ENST00000457772.2
ENST00000455441.1
ENST00000427315.1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr1_+_114471809 3.02 ENST00000426820.2
homeodomain interacting protein kinase 1
chr19_-_10227503 2.99 ENST00000593054.1
eukaryotic translation initiation factor 3, subunit G
chr8_-_21771214 2.98 ENST00000276420.4
docking protein 2, 56kDa
chr3_+_49449636 2.97 ENST00000273590.3
T-cell leukemia translocation altered
chr16_-_67514982 2.96 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr10_+_94451574 2.93 ENST00000492654.2
hematopoietically expressed homeobox
chr5_-_176433350 2.92 ENST00000377227.4
ENST00000377219.2
ubiquitin interaction motif containing 1
chr16_+_8715536 2.91 ENST00000563958.1
ENST00000381920.3
ENST00000564554.1
methyltransferase like 22
chr12_-_96390063 2.90 ENST00000541929.1
histidine ammonia-lyase
chr11_-_2323290 2.85 ENST00000381153.3
chromosome 11 open reading frame 21
chr2_-_85637459 2.82 ENST00000409921.1
capping protein (actin filament), gelsolin-like
chr12_-_13248562 2.82 ENST00000457134.2
ENST00000537302.1
germ cell associated 1
chr5_+_135385202 2.79 ENST00000514554.1
transforming growth factor, beta-induced, 68kDa
chr1_+_25870070 2.76 ENST00000374338.4
low density lipoprotein receptor adaptor protein 1
chr22_+_35776828 2.76 ENST00000216117.8
heme oxygenase (decycling) 1
chr11_+_65407331 2.74 ENST00000527525.1
signal-induced proliferation-associated 1
chr15_+_91427642 2.73 ENST00000328850.3
ENST00000414248.2
feline sarcoma oncogene
chr19_+_41313017 2.72 ENST00000595621.1
ENST00000595051.1
egl-9 family hypoxia-inducible factor 2
chr11_+_1874200 2.68 ENST00000311604.3
lymphocyte-specific protein 1
chr19_+_14491948 2.65 ENST00000358600.3
CD97 molecule
chr15_+_75074410 2.61 ENST00000439220.2
c-src tyrosine kinase
chr8_-_21771182 2.57 ENST00000523932.1
ENST00000544659.1
docking protein 2, 56kDa
chr2_+_68592305 2.57 ENST00000234313.7
pleckstrin
chr6_-_41254403 2.56 ENST00000589614.1
ENST00000334475.6
ENST00000591620.1
ENST00000244709.4
triggering receptor expressed on myeloid cells 1
chr1_-_28520447 2.54 ENST00000539896.1
platelet-activating factor receptor
chr15_+_81589254 2.54 ENST00000394652.2
interleukin 16
chr19_+_17337406 2.54 ENST00000597836.1
occludin/ELL domain containing 1
chr19_+_50321528 2.52 ENST00000312865.6
ENST00000595185.1
ENST00000538643.1
mediator complex subunit 25
chr4_+_2845547 2.49 ENST00000264758.7
ENST00000446856.1
ENST00000398125.1
adducin 1 (alpha)
chr3_-_49449521 2.48 ENST00000431929.1
ENST00000418115.1
ras homolog family member A
chr3_+_20081515 2.46 ENST00000263754.4
K(lysine) acetyltransferase 2B
chr12_-_118797475 2.46 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAO kinase 3
chr14_-_106406090 2.45 ENST00000390593.2
immunoglobulin heavy variable 6-1
chr2_-_85645545 2.42 ENST00000409275.1
capping protein (actin filament), gelsolin-like
chr19_+_36195429 2.42 ENST00000392197.2
zinc finger and BTB domain containing 32
chr5_+_75699149 2.40 ENST00000379730.3
IQ motif containing GTPase activating protein 2
chr5_+_134074191 2.39 ENST00000297156.2
calcium modulating ligand
chr3_-_122512619 2.37 ENST00000383659.1
ENST00000306103.2
HSPB (heat shock 27kDa) associated protein 1
chr8_-_101963482 2.37 ENST00000419477.2
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr3_+_54156664 2.32 ENST00000474759.1
ENST00000288197.5
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chrX_-_153599578 2.32 ENST00000360319.4
ENST00000344736.4
filamin A, alpha
chr18_+_61554932 2.32 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr15_+_81591757 2.31 ENST00000558332.1
interleukin 16
chr12_-_54121261 2.31 ENST00000549784.1
ENST00000262059.4
calcium binding and coiled-coil domain 1
chr8_+_22436248 2.30 ENST00000308354.7
PDZ and LIM domain 2 (mystique)
chr5_-_169725231 2.28 ENST00000046794.5
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr15_+_91427691 2.25 ENST00000559355.1
ENST00000394302.1
feline sarcoma oncogene
chr11_+_65647280 2.25 ENST00000307886.3
ENST00000528419.1
ENST00000526034.1
cathepsin W
chr14_-_74960030 2.25 ENST00000553490.1
ENST00000557510.1
Niemann-Pick disease, type C2
chr14_-_74959994 2.25 ENST00000238633.2
ENST00000434013.2
Niemann-Pick disease, type C2
chr5_+_134074231 2.24 ENST00000514518.1
calcium modulating ligand
chr14_-_74959978 2.23 ENST00000541064.1
Niemann-Pick disease, type C2
chrX_-_52260355 2.13 ENST00000375602.1
ENST00000399800.3
X antigen family, member 1A
chr12_+_117013656 2.12 ENST00000556529.1
microtubule-associated protein 1 light chain 3 beta 2
chr5_+_96038476 2.11 ENST00000511049.1
ENST00000309190.5
ENST00000510156.1
ENST00000509903.1
ENST00000511782.1
ENST00000504465.1
calpastatin
chr11_-_414948 2.10 ENST00000530494.1
ENST00000528209.1
ENST00000431843.2
ENST00000528058.1
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr11_-_72433346 2.08 ENST00000334211.8
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr3_+_54156570 2.07 ENST00000415676.2
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr7_-_150974494 2.07 ENST00000392811.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr21_-_38445443 2.03 ENST00000360525.4
phosphatidylinositol glycan anchor biosynthesis, class P
chr19_-_40971667 2.03 ENST00000263368.4
biliverdin reductase B (flavin reductase (NADPH))
chr1_+_207494853 2.02 ENST00000367064.3
ENST00000367063.2
ENST00000391921.4
ENST00000367067.4
ENST00000314754.8
ENST00000367065.5
ENST00000391920.4
ENST00000367062.4
ENST00000343420.6
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
chrX_+_52511761 1.99 ENST00000399795.3
ENST00000375589.1
X antigen family, member 1C
chr17_+_2699697 1.99 ENST00000254695.8
ENST00000366401.4
ENST00000542807.1
RAP1 GTPase activating protein 2
chr1_+_114471972 1.99 ENST00000369559.4
ENST00000369554.2
homeodomain interacting protein kinase 1
chrX_-_151938171 1.97 ENST00000393902.3
ENST00000417212.1
ENST00000370278.3
melanoma antigen family A, 3
chr22_+_40573921 1.96 ENST00000454349.2
ENST00000335727.9
trinucleotide repeat containing 6B
chr12_-_49504655 1.96 ENST00000551782.1
ENST00000267102.8
limb development membrane protein 1-like
chr12_+_29302119 1.95 ENST00000536681.3
fatty acyl CoA reductase 2
chr12_-_57522813 1.93 ENST00000556155.1
signal transducer and activator of transcription 6, interleukin-4 induced
chr7_+_100450328 1.92 ENST00000540482.1
ENST00000418037.1
ENST00000428758.1
ENST00000275729.3
ENST00000415287.1
ENST00000354161.3
ENST00000416675.1
solute carrier family 12, member 9
chr21_-_38445297 1.92 ENST00000430792.1
ENST00000399103.1
phosphatidylinositol glycan anchor biosynthesis, class P
chr14_-_24711865 1.90 ENST00000399423.4
ENST00000267415.7
TERF1 (TRF1)-interacting nuclear factor 2
chr19_-_47616992 1.90 ENST00000253048.5
zinc finger CCCH-type containing 4
chr8_-_101962777 1.89 ENST00000395951.3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chrX_-_152486108 1.89 ENST00000356661.5
melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
chr14_-_24711470 1.87 ENST00000559969.1
TERF1 (TRF1)-interacting nuclear factor 2
chr12_-_54121212 1.86 ENST00000548263.1
ENST00000430117.2
ENST00000550804.1
ENST00000549173.1
ENST00000551900.1
ENST00000546619.1
ENST00000548177.1
ENST00000549349.1
calcium binding and coiled-coil domain 1
chr6_-_133035185 1.85 ENST00000367928.4
vanin 1
chr11_+_59480899 1.84 ENST00000300150.7
syntaxin 3
chr3_-_50383096 1.83 ENST00000442887.1
ENST00000360165.3
zinc finger, MYND-type containing 10
chr13_-_46961580 1.83 ENST00000378787.3
ENST00000378797.2
ENST00000429979.1
ENST00000378781.3
KIAA0226-like
chr14_-_24711806 1.81 ENST00000540705.1
ENST00000538777.1
ENST00000558566.1
ENST00000559019.1
TERF1 (TRF1)-interacting nuclear factor 2
chr16_+_8715574 1.79 ENST00000561758.1
methyltransferase like 22
chr3_+_49059038 1.79 ENST00000451378.2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr19_-_40971643 1.78 ENST00000595483.1
biliverdin reductase B (flavin reductase (NADPH))
chr19_-_40324767 1.75 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chrX_-_52546189 1.74 ENST00000375570.1
ENST00000429372.2
X antigen family, member 1E
chr12_-_96390108 1.71 ENST00000538703.1
ENST00000261208.3
histidine ammonia-lyase
chr5_-_112257914 1.70 ENST00000513339.1
ENST00000545426.1
ENST00000504247.1
receptor accessory protein 5
chrX_+_52238810 1.69 ENST00000437949.2
ENST00000375616.1
X antigen family, member 1B
chr15_-_42565606 1.69 ENST00000307216.6
ENST00000448392.1
transmembrane protein 87A
chr4_+_2794750 1.67 ENST00000452765.2
ENST00000389838.2
SH3-domain binding protein 2
chr1_+_180165672 1.66 ENST00000443059.1
quiescin Q6 sulfhydryl oxidase 1
chr15_+_75074385 1.66 ENST00000220003.9
c-src tyrosine kinase
chr12_-_15114492 1.64 ENST00000541546.1
Rho GDP dissociation inhibitor (GDI) beta
chr22_+_29702572 1.64 ENST00000407647.2
ENST00000416823.1
ENST00000428622.1
growth arrest-specific 2 like 1
chr13_-_33002279 1.63 ENST00000380130.2
NEDD4 binding protein 2-like 1
chr12_-_81331697 1.62 ENST00000552864.1
lin-7 homolog A (C. elegans)
chr20_-_1600642 1.62 ENST00000381603.3
ENST00000381605.4
ENST00000279477.7
ENST00000568365.1
ENST00000564763.1
signal-regulatory protein beta 1
Uncharacterized protein
chr16_+_75681650 1.58 ENST00000300086.4
telomeric repeat binding factor 2, interacting protein
chr2_-_85636928 1.57 ENST00000449030.1
capping protein (actin filament), gelsolin-like
chr5_+_140501581 1.56 ENST00000194152.1
protocadherin beta 4
chr2_+_241564655 1.55 ENST00000407714.1
G protein-coupled receptor 35
chrX_-_153210107 1.55 ENST00000369997.3
ENST00000393700.3
ENST00000412763.1
renin binding protein
chr11_+_46368975 1.53 ENST00000527911.1
diacylglycerol kinase, zeta
chr2_+_169923577 1.53 ENST00000432060.2
dehydrogenase/reductase (SDR family) member 9
chrX_-_52533295 1.51 ENST00000375578.1
ENST00000396497.3
X antigen family, member 1D
chr18_+_6729698 1.50 ENST00000383472.4
Rho GTPase activating protein 28
chr19_+_17337027 1.48 ENST00000601529.1
ENST00000600232.1
occludin/ELL domain containing 1
chr19_-_44174330 1.48 ENST00000340093.3
plasminogen activator, urokinase receptor
chr3_+_9773409 1.47 ENST00000433861.2
ENST00000424362.1
ENST00000383829.2
ENST00000302054.3
ENST00000420291.1
bromodomain and PHD finger containing, 1
chr13_-_47012325 1.46 ENST00000409879.2
KIAA0226-like
chr22_+_39760130 1.42 ENST00000381535.4
synaptogyrin 1
chr3_+_14166440 1.42 ENST00000306077.4
transmembrane protein 43
chr21_-_38445011 1.41 ENST00000464265.1
ENST00000399102.1
phosphatidylinositol glycan anchor biosynthesis, class P
chr11_-_119252425 1.40 ENST00000260187.2
ubiquitin specific peptidase 2
chr2_-_24307635 1.40 ENST00000313482.4
tumor protein p53 inducible protein 3
chr8_-_101348408 1.37 ENST00000519527.1
ENST00000522369.1
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr14_-_65569057 1.37 ENST00000555419.1
ENST00000341653.2
MYC associated factor X
chr11_-_64512469 1.37 ENST00000377485.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr10_-_135122603 1.37 ENST00000368563.2
tubulin, gamma complex associated protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 11.3 GO:1902490 regulation of sperm capacitation(GO:1902490)
3.4 13.7 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
3.1 12.5 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
2.9 17.5 GO:0071105 response to interleukin-11(GO:0071105)
2.8 8.4 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
1.9 5.6 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
1.8 8.8 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
1.7 6.7 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
1.6 9.9 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
1.5 4.6 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
1.5 4.4 GO:1902771 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
1.4 4.3 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
1.4 5.6 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
1.2 4.9 GO:0030185 nitric oxide transport(GO:0030185)
1.2 16.3 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
1.0 4.0 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
1.0 2.9 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.9 5.6 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.9 2.8 GO:0006788 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806)
0.9 5.5 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.9 4.4 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.9 4.3 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.8 2.5 GO:1904301 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.8 2.5 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.8 4.1 GO:0051622 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.8 2.5 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.7 3.0 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.7 2.0 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.6 2.5 GO:2001178 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.6 3.7 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.6 2.4 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.6 3.5 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.6 5.0 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.5 2.7 GO:0042631 cellular response to water deprivation(GO:0042631)
0.5 1.0 GO:0002125 maternal aggressive behavior(GO:0002125)
0.5 3.5 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.5 4.0 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.5 2.0 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.5 1.9 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.5 4.6 GO:0001955 blood vessel maturation(GO:0001955)
0.4 3.5 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.4 8.6 GO:0006853 carnitine shuttle(GO:0006853)
0.4 2.1 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.4 2.6 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.4 6.8 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.4 2.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.4 4.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.4 2.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.4 1.6 GO:0071461 cellular response to redox state(GO:0071461)
0.4 1.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.4 4.1 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.4 1.6 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.4 2.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.4 3.0 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.4 2.6 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.4 2.5 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.4 6.7 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.3 2.7 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.3 0.3 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.3 3.0 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.3 3.8 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.3 6.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.3 1.2 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.3 1.2 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.3 1.2 GO:0002317 plasma cell differentiation(GO:0002317)
0.3 0.8 GO:0051684 maintenance of Golgi location(GO:0051684)
0.3 5.1 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.3 0.8 GO:0016999 antibiotic metabolic process(GO:0016999) cellular amide catabolic process(GO:0043605)
0.3 1.8 GO:0036159 inner dynein arm assembly(GO:0036159)
0.3 2.8 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.2 1.0 GO:0014040 positive regulation of Schwann cell differentiation(GO:0014040)
0.2 1.7 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.2 0.2 GO:0043366 beta selection(GO:0043366)
0.2 1.6 GO:0035624 receptor transactivation(GO:0035624)
0.2 1.1 GO:2000782 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
0.2 3.8 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.2 0.9 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.2 0.9 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.2 1.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.2 0.6 GO:0090035 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.2 0.6 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.2 1.4 GO:0071763 nuclear membrane organization(GO:0071763)
0.2 0.9 GO:0035063 nuclear speck organization(GO:0035063)
0.2 1.9 GO:0015939 pantothenate metabolic process(GO:0015939)
0.2 1.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 0.5 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.2 5.3 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.2 4.6 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.2 2.4 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.2 4.6 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.2 3.4 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.2 0.2 GO:1903179 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
0.2 3.7 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.2 1.8 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 6.4 GO:0030261 chromosome condensation(GO:0030261)
0.2 1.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.2 0.3 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.2 2.3 GO:0090168 Golgi reassembly(GO:0090168)
0.2 0.9 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.2 2.1 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1 3.9 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.1 2.4 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 1.0 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 1.6 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.4 GO:0032759 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.1 1.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 7.2 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.1 11.7 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 1.1 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.1 2.6 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1 2.1 GO:0045475 locomotor rhythm(GO:0045475)
0.1 2.0 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 6.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 2.3 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.6 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 1.8 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.2 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.1 0.9 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 2.7 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.7 GO:0051105 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.1 0.1 GO:0071306 cellular response to vitamin E(GO:0071306)
0.1 0.4 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.1 12.9 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.1 0.2 GO:0060023 soft palate development(GO:0060023)
0.1 0.3 GO:0061461 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.1 3.0 GO:0007035 vacuolar acidification(GO:0007035)
0.1 0.3 GO:0001694 histamine biosynthetic process(GO:0001694)
0.1 0.4 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 2.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.7 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 1.9 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.6 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856) response to oleic acid(GO:0034201)
0.1 1.0 GO:0006930 negative regulation of receptor internalization(GO:0002091) substrate-dependent cell migration, cell extension(GO:0006930)
0.1 0.9 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 0.3 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.9 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.1 1.1 GO:0001895 retina homeostasis(GO:0001895)
0.1 2.0 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.5 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 0.2 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.1 0.4 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 6.7 GO:0045576 mast cell activation(GO:0045576)
0.1 0.8 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 1.2 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 2.6 GO:0035902 response to immobilization stress(GO:0035902)
0.1 4.8 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.1 0.3 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.3 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.1 1.9 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.3 GO:0007386 compartment pattern specification(GO:0007386)
0.1 1.4 GO:0007517 muscle organ development(GO:0007517)
0.1 0.2 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.5 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 0.2 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1 0.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 0.7 GO:0030220 platelet formation(GO:0030220)
0.1 0.3 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1 0.2 GO:0048852 hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852)
0.1 0.9 GO:0046688 response to copper ion(GO:0046688)
0.1 1.3 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 0.7 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.1 1.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.1 0.2 GO:0018201 N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201)
0.1 0.6 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 1.0 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.0 0.8 GO:0007567 parturition(GO:0007567)
0.0 1.2 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.6 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 1.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 3.8 GO:0048678 response to axon injury(GO:0048678)
0.0 0.8 GO:0006952 defense response(GO:0006952)
0.0 1.9 GO:0001881 receptor recycling(GO:0001881)
0.0 0.3 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.2 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 2.9 GO:0006968 cellular defense response(GO:0006968)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 4.8 GO:0050807 regulation of synapse organization(GO:0050807)
0.0 0.5 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.5 GO:0097659 transcription, DNA-templated(GO:0006351) nucleic acid-templated transcription(GO:0097659)
0.0 2.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 3.2 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.0 0.5 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 4.1 GO:0002819 regulation of adaptive immune response(GO:0002819)
0.0 0.9 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.4 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 1.1 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.9 GO:0002456 T cell mediated immunity(GO:0002456)
0.0 0.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.1 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.9 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423)
0.0 0.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 1.3 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.9 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 1.0 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.9 GO:0002763 positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.0 0.6 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 1.5 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.8 GO:0016486 peptide hormone processing(GO:0016486)
0.0 2.4 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 2.9 GO:0002576 platelet degranulation(GO:0002576)
0.0 1.0 GO:0006739 NADP metabolic process(GO:0006739)
0.0 0.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.6 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0042398 cellular modified amino acid biosynthetic process(GO:0042398)
0.0 0.4 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 1.6 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.0 0.3 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 0.6 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.2 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) establishment of mitochondrion localization(GO:0051654)
0.0 1.0 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.8 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 0.2 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.4 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.3 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
1.1 5.6 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.9 9.9 GO:0070531 BRCA1-A complex(GO:0070531)
0.8 2.3 GO:0031523 Myb complex(GO:0031523)
0.7 6.3 GO:0033391 chromatoid body(GO:0033391)
0.7 5.5 GO:0045179 apical cortex(GO:0045179)
0.7 4.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.6 6.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.6 9.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.6 12.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.6 11.3 GO:0097225 sperm midpiece(GO:0097225)
0.5 11.6 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.5 1.8 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.5 2.3 GO:0036398 TCR signalosome(GO:0036398)
0.4 3.5 GO:0035976 AP1 complex(GO:0035976)
0.4 4.0 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.3 4.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.3 1.4 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.3 2.5 GO:0000125 PCAF complex(GO:0000125)
0.3 1.8 GO:0005787 signal peptidase complex(GO:0005787)
0.3 1.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.2 20.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.2 1.6 GO:0070187 telosome(GO:0070187)
0.2 2.4 GO:0071438 invadopodium membrane(GO:0071438)
0.2 1.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.2 0.9 GO:0032044 DSIF complex(GO:0032044)
0.2 3.0 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.2 0.8 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 0.9 GO:0045298 tubulin complex(GO:0045298)
0.2 15.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 30.2 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.2 4.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 1.9 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 2.7 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 4.4 GO:0042629 mast cell granule(GO:0042629)
0.1 0.7 GO:0030061 mitochondrial crista(GO:0030061)
0.1 6.2 GO:0001772 immunological synapse(GO:0001772)
0.1 4.6 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.4 GO:0071159 NF-kappaB complex(GO:0071159)
0.1 3.0 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 5.8 GO:0031201 SNARE complex(GO:0031201)
0.1 7.7 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 1.3 GO:0060077 inhibitory synapse(GO:0060077)
0.1 5.8 GO:0000786 nucleosome(GO:0000786)
0.1 1.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 14.3 GO:0031225 anchored component of membrane(GO:0031225)
0.1 12.0 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.3 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.1 1.1 GO:0005577 fibrinogen complex(GO:0005577)
0.1 2.1 GO:0071564 npBAF complex(GO:0071564)
0.1 1.7 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 0.8 GO:0045495 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 0.5 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 0.9 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.4 GO:1990037 Lewy body core(GO:1990037)
0.1 0.5 GO:0033268 node of Ranvier(GO:0033268)
0.1 1.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 6.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 1.6 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.5 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 8.0 GO:0016605 PML body(GO:0016605)
0.1 1.6 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 6.0 GO:0031902 late endosome membrane(GO:0031902)
0.1 1.2 GO:0005686 U2 snRNP(GO:0005686)
0.1 3.6 GO:0043195 terminal bouton(GO:0043195)
0.1 0.3 GO:0032021 NELF complex(GO:0032021)
0.1 2.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 2.6 GO:0030286 dynein complex(GO:0030286)
0.0 2.2 GO:0043034 costamere(GO:0043034)
0.0 0.7 GO:0042599 lamellar body(GO:0042599)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 8.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 2.7 GO:0005901 caveola(GO:0005901)
0.0 2.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.6 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.0 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.3 GO:0001741 XY body(GO:0001741)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 2.0 GO:0005902 microvillus(GO:0005902)
0.0 2.2 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 2.8 GO:0005604 basement membrane(GO:0005604)
0.0 1.7 GO:0030315 T-tubule(GO:0030315)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.4 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 3.5 GO:0072562 blood microparticle(GO:0072562)
0.0 0.8 GO:0016235 aggresome(GO:0016235)
0.0 1.6 GO:0005769 early endosome(GO:0005769)
0.0 0.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 2.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.3 GO:0030667 secretory granule membrane(GO:0030667)
0.0 5.5 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.0 GO:0031901 early endosome membrane(GO:0031901)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 11.0 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
2.8 8.4 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
1.7 8.6 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
1.4 4.3 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
1.2 17.4 GO:0050693 LBD domain binding(GO:0050693)
1.2 22.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
1.2 4.6 GO:0016841 ammonia-lyase activity(GO:0016841)
1.0 3.0 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
1.0 3.8 GO:0004074 biliverdin reductase activity(GO:0004074)
0.9 5.6 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.9 2.8 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.9 6.2 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.8 4.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.8 4.9 GO:0030492 hemoglobin binding(GO:0030492)
0.8 2.4 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.7 12.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.7 2.0 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.6 6.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.6 2.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.5 10.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.5 11.6 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.5 2.5 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.5 3.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.5 2.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.5 6.4 GO:0046870 cadmium ion binding(GO:0046870)
0.5 3.8 GO:0004565 beta-galactosidase activity(GO:0004565)
0.5 6.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.5 0.9 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.4 1.7 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
0.4 1.2 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.4 1.2 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.4 1.2 GO:0048030 disaccharide binding(GO:0048030)
0.4 1.5 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.4 1.9 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.4 2.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.3 1.0 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.3 1.2 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.3 5.5 GO:0043274 phospholipase binding(GO:0043274)
0.3 3.3 GO:0004645 phosphorylase activity(GO:0004645)
0.3 2.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 4.8 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.3 1.5 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.3 5.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.3 0.6 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.3 2.7 GO:0019826 oxygen sensor activity(GO:0019826)
0.3 5.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.3 1.8 GO:0050544 icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.3 1.5 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.3 2.5 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.2 1.4 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.2 18.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 4.9 GO:0042609 CD4 receptor binding(GO:0042609)
0.2 0.8 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.2 4.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 3.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 13.2 GO:0070063 RNA polymerase binding(GO:0070063)
0.2 0.6 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.2 5.9 GO:0042605 peptide antigen binding(GO:0042605)
0.2 2.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 0.6 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.2 0.7 GO:0070051 fibrinogen binding(GO:0070051)
0.2 0.9 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 1.9 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 1.2 GO:0008142 oxysterol binding(GO:0008142)
0.2 2.3 GO:0008234 cysteine-type endopeptidase activity(GO:0004197) cysteine-type peptidase activity(GO:0008234)
0.2 0.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.2 1.9 GO:0097016 L27 domain binding(GO:0097016)
0.2 1.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 0.6 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 1.2 GO:0019863 IgE binding(GO:0019863)
0.1 1.6 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 1.6 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 5.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 3.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 5.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 2.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.5 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.9 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 1.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 2.6 GO:0070840 dynein complex binding(GO:0070840)
0.1 2.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.4 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 5.6 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.9 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 3.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 3.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 2.5 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 0.5 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.3 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 1.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 4.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.3 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 0.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 1.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.4 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 1.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.7 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 1.7 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.7 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 0.7 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.3 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.1 1.3 GO:0051400 BH domain binding(GO:0051400)
0.1 0.8 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 3.8 GO:0070888 E-box binding(GO:0070888)
0.1 3.3 GO:0051219 phosphoprotein binding(GO:0051219)
0.1 1.3 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 0.2 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.1 5.1 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 0.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 1.6 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 2.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.6 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.2 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 0.4 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 1.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 1.7 GO:0030507 spectrin binding(GO:0030507)
0.0 1.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.3 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.7 GO:0070330 aromatase activity(GO:0070330)
0.0 1.6 GO:0004866 endopeptidase inhibitor activity(GO:0004866) endopeptidase regulator activity(GO:0061135)
0.0 2.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 3.5 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.7 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 2.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.5 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 1.4 GO:0043621 protein self-association(GO:0043621)
0.0 1.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 8.1 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.9 GO:0097110 scaffold protein binding(GO:0097110)
0.0 1.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 8.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.0 GO:0030332 cyclin binding(GO:0030332)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.6 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 8.7 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.5 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 2.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 1.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 2.5 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.2 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 0.2 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0097643 amylin receptor activity(GO:0097643)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.5 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 1.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.9 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 8.0 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.3 16.8 PID RAS PATHWAY Regulation of Ras family activation
0.3 5.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 12.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 17.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.2 2.0 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.2 5.6 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.2 1.0 PID IL5 PATHWAY IL5-mediated signaling events
0.2 13.0 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.2 8.9 PID ATM PATHWAY ATM pathway
0.2 13.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.2 4.4 PID EPO PATHWAY EPO signaling pathway
0.1 21.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 6.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 7.2 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 2.3 PID IGF1 PATHWAY IGF1 pathway
0.1 6.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 5.0 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 2.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 8.1 PID CMYB PATHWAY C-MYB transcription factor network
0.1 1.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 2.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 2.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.1 PID LKB1 PATHWAY LKB1 signaling events
0.0 3.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 2.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 8.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.5 PID AURORA A PATHWAY Aurora A signaling
0.0 0.6 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.4 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 17.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.5 4.9 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.5 11.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.4 8.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.4 19.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.4 8.8 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.3 9.8 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.3 6.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.3 7.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 5.0 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 5.6 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.2 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 6.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 2.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 4.6 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.2 2.0 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.2 4.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 1.6 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.2 3.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.2 3.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 5.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 7.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 6.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 21.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 2.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 3.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 0.9 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 3.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 2.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 2.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 3.8 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.1 2.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 6.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 0.9 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 0.7 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 0.6 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.1 1.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 0.4 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 6.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.6 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 3.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 1.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 2.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.2 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 2.2 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 0.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.6 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.9 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 1.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.9 REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0 2.9 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 0.5 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions