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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for MESP1

Z-value: 0.61

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Transcription factors associated with MESP1

Gene Symbol Gene ID Gene Info
ENSG00000166823.5 mesoderm posterior bHLH transcription factor 1

Activity profile of MESP1 motif

Sorted Z-values of MESP1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_116165754 26.96 ENST00000405348.1
caveolin 1, caveolae protein, 22kDa
chr3_-_182833863 26.41 ENST00000492597.1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr7_+_116166331 23.66 ENST00000393468.1
ENST00000393467.1
caveolin 1, caveolae protein, 22kDa
chr19_+_16186903 20.32 ENST00000588507.1
tropomyosin 4
chr1_-_24126023 19.71 ENST00000429356.1
UDP-galactose-4-epimerase
chr12_+_53342625 17.00 ENST00000388837.2
ENST00000550600.1
ENST00000388835.3
keratin 18
chr1_-_95392635 16.89 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
calponin 3, acidic
chr7_+_12727250 16.07 ENST00000404894.1
ADP-ribosylation factor-like 4A
chr11_+_86511569 15.82 ENST00000441050.1
protease, serine, 23
chr19_+_41725088 15.54 ENST00000301178.4
AXL receptor tyrosine kinase
chr5_-_43557791 15.48 ENST00000338972.4
ENST00000511321.1
ENST00000515338.1
poly(A) binding protein interacting protein 1
chr3_+_49059038 15.03 ENST00000451378.2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr3_+_172468472 14.89 ENST00000232458.5
ENST00000392692.3
epithelial cell transforming sequence 2 oncogene
chr11_+_35198243 14.69 ENST00000528455.1
CD44 molecule (Indian blood group)
chr18_+_29077990 14.66 ENST00000261590.8
desmoglein 2
chr5_+_52856456 14.65 ENST00000296684.5
ENST00000506765.1
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
chr19_+_16187085 14.57 ENST00000300933.4
tropomyosin 4
chr17_+_39411636 14.43 ENST00000394008.1
keratin associated protein 9-9
chr14_+_56078695 14.22 ENST00000416613.1
kinectin 1 (kinesin receptor)
chr19_-_42806723 14.03 ENST00000262890.3
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr3_+_105086056 13.98 ENST00000472644.2
activated leukocyte cell adhesion molecule
chr11_-_65667997 13.81 ENST00000312562.2
ENST00000534222.1
FOS-like antigen 1
chr12_+_48357340 13.70 ENST00000256686.6
ENST00000549288.1
ENST00000552561.1
ENST00000546749.1
ENST00000552546.1
ENST00000550552.1
transmembrane protein 106C
chr12_+_48357401 13.40 ENST00000429772.2
ENST00000449758.2
transmembrane protein 106C
chr11_+_35198118 13.40 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
CD44 molecule (Indian blood group)
chr3_+_172468505 13.39 ENST00000427830.1
ENST00000417960.1
ENST00000428567.1
ENST00000366090.2
ENST00000426894.1
epithelial cell transforming sequence 2 oncogene
chr5_+_138089100 13.26 ENST00000520339.1
ENST00000355078.5
ENST00000302763.7
ENST00000518910.1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr2_-_175870085 13.20 ENST00000409156.3
chimerin 1
chr11_-_65667884 13.10 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOS-like antigen 1
chr3_-_149688896 13.05 ENST00000239940.7
profilin 2
chr6_-_30712313 13.02 ENST00000376377.2
ENST00000259874.5
immediate early response 3
chr15_+_78833071 12.98 ENST00000559365.1
proteasome (prosome, macropain) subunit, alpha type, 4
chr17_+_52978156 12.77 ENST00000348161.4
target of myb1 (chicken)-like 1
chr11_-_102323489 12.42 ENST00000361236.3
transmembrane protein 123
chr3_-_149688502 12.32 ENST00000481767.1
ENST00000475518.1
profilin 2
chr12_-_50677255 12.21 ENST00000551691.1
ENST00000394943.3
ENST00000341247.4
LIM domain and actin binding 1
chr19_-_48894104 12.06 ENST00000597017.1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr2_-_37899323 11.97 ENST00000295324.3
ENST00000457889.1
CDC42 effector protein (Rho GTPase binding) 3
chr3_+_105085734 11.86 ENST00000306107.5
activated leukocyte cell adhesion molecule
chr1_-_113249948 11.78 ENST00000339083.7
ENST00000369642.3
ras homolog family member C
chr3_-_134093275 11.71 ENST00000513145.1
ENST00000422605.2
angiomotin like 2
chr1_-_24126892 11.70 ENST00000374497.3
ENST00000425913.1
UDP-galactose-4-epimerase
chr1_-_150669500 11.61 ENST00000271732.3
golgi phosphoprotein 3-like
chr19_-_42806842 11.54 ENST00000596265.1
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chrX_-_153775426 11.42 ENST00000393562.2
glucose-6-phosphate dehydrogenase
chr19_-_13068012 11.16 ENST00000316939.1
growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr1_+_32687971 11.04 ENST00000373586.1
eukaryotic translation initiation factor 3, subunit I
chr15_+_78832747 11.00 ENST00000560217.1
ENST00000044462.7
ENST00000559082.1
ENST00000559948.1
ENST00000413382.2
ENST00000559146.1
ENST00000558281.1
proteasome (prosome, macropain) subunit, alpha type, 4
chr20_+_44441304 10.94 ENST00000352551.5
ubiquitin-conjugating enzyme E2C
chr7_-_99698338 10.52 ENST00000354230.3
ENST00000425308.1
minichromosome maintenance complex component 7
chr1_-_85930823 10.42 ENST00000284031.8
ENST00000539042.1
dimethylarginine dimethylaminohydrolase 1
chr20_+_44441215 10.37 ENST00000356455.4
ENST00000405520.1
ubiquitin-conjugating enzyme E2C
chr17_+_48133459 10.36 ENST00000320031.8
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr6_+_47445467 10.26 ENST00000359314.5
CD2-associated protein
chr4_+_166248775 10.17 ENST00000261507.6
ENST00000507013.1
ENST00000393766.2
ENST00000504317.1
methylsterol monooxygenase 1
chr6_-_31697255 10.01 ENST00000436437.1
dimethylarginine dimethylaminohydrolase 2
chr12_+_6309963 9.85 ENST00000382515.2
CD9 molecule
chr11_+_19798964 9.78 ENST00000527559.2
neuron navigator 2
chr1_-_113249678 9.76 ENST00000369633.2
ENST00000425265.2
ENST00000369632.2
ENST00000436685.2
ras homolog family member C
chr6_-_75994536 9.73 ENST00000475111.2
ENST00000230461.6
transmembrane protein 30A
chr5_-_43557129 9.70 ENST00000514514.1
ENST00000504075.1
ENST00000306846.3
ENST00000436644.2
poly(A) binding protein interacting protein 1
chr1_-_113249734 9.65 ENST00000484054.3
ENST00000369636.2
ENST00000369637.1
ENST00000285735.2
ENST00000369638.2
ras homolog family member C
chr4_+_169418195 9.64 ENST00000261509.6
ENST00000335742.7
palladin, cytoskeletal associated protein
chr3_-_149688655 9.62 ENST00000461930.1
ENST00000423691.2
ENST00000490975.1
ENST00000461868.1
ENST00000452853.2
profilin 2
chr11_+_19799327 9.56 ENST00000540292.1
neuron navigator 2
chr12_-_53343602 9.45 ENST00000546897.1
ENST00000552551.1
keratin 8
chr17_-_73149921 9.41 ENST00000481647.1
ENST00000470924.1
hematological and neurological expressed 1
chr6_-_3227877 9.41 ENST00000259818.7
tubulin, beta 2B class IIb
chr8_-_71519889 9.38 ENST00000521425.1
translocation associated membrane protein 1
chr12_-_15942309 9.37 ENST00000544064.1
ENST00000543523.1
ENST00000536793.1
epidermal growth factor receptor pathway substrate 8
chr8_-_71520513 9.37 ENST00000262213.2
ENST00000536748.1
ENST00000518678.1
translocation associated membrane protein 1
chr5_+_34656569 9.35 ENST00000428746.2
retinoic acid induced 14
chr11_-_102323740 9.34 ENST00000398136.2
transmembrane protein 123
chr17_-_79805146 9.34 ENST00000415593.1
prolyl 4-hydroxylase, beta polypeptide
chr8_-_141931287 9.31 ENST00000517887.1
protein tyrosine kinase 2
chr8_+_104311059 9.28 ENST00000358755.4
ENST00000523739.1
ENST00000540287.1
frizzled family receptor 6
chr2_-_190044480 9.21 ENST00000374866.3
collagen, type V, alpha 2
chr1_+_182992545 9.16 ENST00000258341.4
laminin, gamma 1 (formerly LAMB2)
chr10_+_70748487 9.14 ENST00000361983.4
KIAA1279
chrX_+_40440146 9.13 ENST00000535539.1
ENST00000378438.4
ENST00000436783.1
ENST00000544975.1
ENST00000535777.1
ENST00000447485.1
ENST00000423649.1
ATPase, H+ transporting, lysosomal accessory protein 2
chr1_-_109825719 9.10 ENST00000369904.3
ENST00000369903.2
ENST00000429031.1
ENST00000418914.2
ENST00000409267.1
proline/serine-rich coiled-coil 1
chr3_+_158787041 9.09 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1 readthrough
chr20_+_3776936 8.95 ENST00000439880.2
cell division cycle 25B
chr4_-_157892498 8.93 ENST00000502773.1
platelet derived growth factor C
chr6_+_34204642 8.90 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr16_-_29466285 8.89 ENST00000330978.3
bolA family member 2
chr11_-_65626753 8.87 ENST00000526975.1
ENST00000531413.1
cofilin 1 (non-muscle)
chr20_+_17550691 8.83 ENST00000474024.1
destrin (actin depolymerizing factor)
chr9_+_138392483 8.80 ENST00000241600.5
mitochondrial ribosomal protein S2
chr21_-_27542972 8.66 ENST00000346798.3
ENST00000439274.2
ENST00000354192.3
ENST00000348990.5
ENST00000357903.3
ENST00000358918.3
ENST00000359726.3
amyloid beta (A4) precursor protein
chr1_-_109825751 8.62 ENST00000369907.3
ENST00000438534.2
ENST00000369909.2
ENST00000409138.2
proline/serine-rich coiled-coil 1
chr18_-_71959159 8.54 ENST00000494131.2
ENST00000397914.4
ENST00000340533.4
cytochrome b5 type A (microsomal)
chr3_-_167452703 8.52 ENST00000497056.2
ENST00000473645.2
programmed cell death 10
chr17_+_34842473 8.51 ENST00000490126.2
ENST00000225410.4
zinc finger, HIT-type containing 3
chr9_-_117880477 8.50 ENST00000534839.1
ENST00000340094.3
ENST00000535648.1
ENST00000346706.3
ENST00000345230.3
ENST00000350763.4
tenascin C
chr2_+_231921574 8.48 ENST00000308696.6
ENST00000373635.4
ENST00000440838.1
ENST00000409643.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr19_-_42806919 8.40 ENST00000595530.1
ENST00000538771.1
ENST00000601865.1
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr12_-_110318226 8.24 ENST00000544393.1
glycolipid transfer protein
chr12_+_116997186 8.17 ENST00000306985.4
microtubule-associated protein 1 light chain 3 beta 2
chr15_+_57210961 8.13 ENST00000557843.1
transcription factor 12
chr14_+_90863327 8.13 ENST00000356978.4
calmodulin 1 (phosphorylase kinase, delta)
chr22_-_24322660 8.11 ENST00000404092.1
D-dopachrome tautomerase
chr21_-_30445886 8.04 ENST00000431234.1
ENST00000540844.1
ENST00000286788.4
chaperonin containing TCP1, subunit 8 (theta)
chr8_+_22437965 7.96 ENST00000409141.1
ENST00000265810.4
PDZ and LIM domain 2 (mystique)
chr2_-_106054952 7.90 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
four and a half LIM domains 2
chr5_-_150466692 7.90 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNFAIP3 interacting protein 1
chr19_-_50432782 7.87 ENST00000413454.1
ENST00000596437.1
ENST00000341114.3
ENST00000595948.1
nucleoporin 62kDa
interleukin 4 induced 1
chr6_+_22569784 7.83 ENST00000510882.2
hepatoma derived growth factor-like 1
chr3_-_167452614 7.81 ENST00000392750.2
ENST00000464360.1
ENST00000492139.1
ENST00000471885.1
ENST00000470131.1
programmed cell death 10
chr8_-_103876383 7.81 ENST00000347770.4
antizyme inhibitor 1
chr12_-_77272765 7.79 ENST00000547435.1
ENST00000552330.1
ENST00000546966.1
ENST00000311083.5
cysteine and glycine-rich protein 2
chr1_+_45478568 7.79 ENST00000428106.1
uroporphyrinogen decarboxylase
chr8_+_22438009 7.78 ENST00000409417.1
PDZ and LIM domain 2 (mystique)
chr10_-_33625154 7.77 ENST00000265371.4
neuropilin 1
chr17_-_38978847 7.72 ENST00000269576.5
keratin 10
chr21_+_30502806 7.71 ENST00000399928.1
ENST00000399926.1
MAP3K7 C-terminal like
chr10_+_12237924 7.62 ENST00000429258.2
ENST00000281141.4
cell division cycle 123
chr11_+_32112431 7.62 ENST00000054950.3
reticulocalbin 1, EF-hand calcium binding domain
chr17_+_34842512 7.60 ENST00000588253.1
ENST00000592616.1
ENST00000590858.1
ENST00000588357.1
zinc finger, HIT-type containing 3
chr13_-_23949671 7.57 ENST00000402364.1
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr3_+_52719936 7.55 ENST00000418458.1
ENST00000394799.2
guanine nucleotide binding protein-like 3 (nucleolar)
chr11_-_88070920 7.51 ENST00000524463.1
ENST00000227266.5
cathepsin C
chr12_+_56211703 7.50 ENST00000243045.5
ENST00000552672.1
ENST00000550836.1
ORM1-like 2 (S. cerevisiae)
chr12_+_96252706 7.45 ENST00000266735.5
ENST00000553192.1
ENST00000552085.1
small nuclear ribonucleoprotein polypeptide F
chr10_+_12238171 7.45 ENST00000378900.2
ENST00000442050.1
cell division cycle 123
chr8_-_103876965 7.38 ENST00000337198.5
antizyme inhibitor 1
chr22_-_36236265 7.34 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RNA binding protein, fox-1 homolog (C. elegans) 2
chr11_+_18416103 7.30 ENST00000543445.1
ENST00000430553.2
ENST00000396222.2
ENST00000535451.1
lactate dehydrogenase A
chr10_+_60028818 7.27 ENST00000333926.5
CDGSH iron sulfur domain 1
chr4_-_139163491 7.27 ENST00000280612.5
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr4_-_76598544 7.25 ENST00000515457.1
ENST00000357854.3
GTPase activating protein (SH3 domain) binding protein 2
chr22_+_31488433 7.20 ENST00000455608.1
smoothelin
chr5_+_102201722 7.20 ENST00000274392.9
ENST00000455264.2
peptidylglycine alpha-amidating monooxygenase
chr8_+_22436248 7.20 ENST00000308354.7
PDZ and LIM domain 2 (mystique)
chr8_-_141810634 7.17 ENST00000521986.1
ENST00000523539.1
ENST00000538769.1
protein tyrosine kinase 2
chr5_+_138940742 7.12 ENST00000398733.3
ENST00000253815.2
ENST00000505007.1
ubiquitin-conjugating enzyme E2D 2
chr16_+_771663 7.10 ENST00000568916.1
family with sequence similarity 173, member A
chr22_+_31489344 7.08 ENST00000404574.1
smoothelin
chrX_-_154688276 7.07 ENST00000369445.2
coagulation factor VIII-associated 3
chr10_-_74856608 6.94 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
prolyl 4-hydroxylase, alpha polypeptide I
chr5_+_102201509 6.88 ENST00000348126.2
ENST00000379787.4
peptidylglycine alpha-amidating monooxygenase
chr4_-_103749179 6.88 ENST00000502690.1
ubiquitin-conjugating enzyme E2D 3
chr17_-_8534031 6.83 ENST00000411957.1
ENST00000396239.1
ENST00000379980.4
myosin, heavy chain 10, non-muscle
chr15_+_57210818 6.68 ENST00000438423.2
ENST00000267811.5
ENST00000452095.2
ENST00000559609.1
ENST00000333725.5
transcription factor 12
chr12_+_6309517 6.61 ENST00000382519.4
ENST00000009180.4
CD9 molecule
chr11_+_18416133 6.60 ENST00000227157.4
ENST00000478970.2
ENST00000495052.1
lactate dehydrogenase A
chr4_-_76598296 6.57 ENST00000395719.3
GTPase activating protein (SH3 domain) binding protein 2
chr1_-_26232951 6.57 ENST00000426559.2
ENST00000455785.2
stathmin 1
chr8_-_145018905 6.55 ENST00000398774.2
plectin
chr22_+_40742497 6.51 ENST00000216194.7
adenylosuccinate lyase
chr20_-_43133491 6.48 ENST00000411544.1
serine incorporator 3
chr16_-_103572 6.45 ENST00000293860.5
polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
chr14_+_90864504 6.44 ENST00000544280.2
calmodulin 1 (phosphorylase kinase, delta)
chr1_-_159893507 6.44 ENST00000368096.1
transgelin 2
chr6_+_36646435 6.37 ENST00000244741.5
ENST00000405375.1
ENST00000373711.2
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chrX_+_150151752 6.37 ENST00000325307.7
high mobility group box 3
chr13_+_115000521 6.36 ENST00000252457.5
ENST00000375308.1
cell division cycle 16
chr22_-_36236623 6.35 ENST00000405409.2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr2_-_133427767 6.34 ENST00000397463.2
LY6/PLAUR domain containing 1
chr3_-_120170052 6.21 ENST00000295633.3
follistatin-like 1
chr2_+_238395803 6.17 ENST00000264605.3
melanophilin
chr8_-_144886321 6.16 ENST00000526832.1
scribbled planar cell polarity protein
chr13_-_37573432 6.11 ENST00000413537.2
ENST00000443765.1
ENST00000239891.3
ALG5, dolichyl-phosphate beta-glucosyltransferase
chr1_-_108742957 6.09 ENST00000565488.1
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr7_+_16793160 6.07 ENST00000262067.4
tetraspanin 13
chr1_+_120254510 6.05 ENST00000369409.4
phosphoglycerate dehydrogenase
chr22_+_18593446 6.05 ENST00000316027.6
tubulin, alpha 8
chr11_+_69455855 6.05 ENST00000227507.2
ENST00000536559.1
cyclin D1
chr5_-_142814241 6.05 ENST00000504572.1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr16_-_69368774 6.00 ENST00000562949.1
Conserved oligomeric Golgi complex subunit 8
chr15_+_77224045 5.96 ENST00000320963.5
ENST00000394883.3
reticulocalbin 2, EF-hand calcium binding domain
chr17_-_8534067 5.94 ENST00000360416.3
ENST00000269243.4
myosin, heavy chain 10, non-muscle
chrX_+_47444613 5.86 ENST00000445623.1
TIMP metallopeptidase inhibitor 1
chr8_-_80993010 5.83 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
tumor protein D52
chr15_+_57511609 5.81 ENST00000543579.1
ENST00000537840.1
ENST00000343827.3
transcription factor 12
chr14_+_24605389 5.80 ENST00000382708.3
ENST00000561435.1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr17_-_79827808 5.79 ENST00000580685.1
Rho GDP dissociation inhibitor (GDI) alpha
chrX_-_118986911 5.79 ENST00000276201.2
ENST00000345865.2
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr14_-_71107921 5.76 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
chrX_-_153285251 5.73 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
interleukin-1 receptor-associated kinase 1
chr19_+_40146534 5.71 ENST00000392051.3
lectin, galactoside-binding, soluble, 16
chr7_-_148580563 5.71 ENST00000476773.1
enhancer of zeste homolog 2 (Drosophila)
chr16_-_50402690 5.69 ENST00000394689.2
bromodomain containing 7
chr11_-_85779971 5.67 ENST00000393346.3
phosphatidylinositol binding clathrin assembly protein
chr3_+_180630090 5.62 ENST00000357559.4
ENST00000305586.7
fragile X mental retardation, autosomal homolog 1
chrX_-_153141302 5.56 ENST00000361699.4
ENST00000543994.1
ENST00000370057.3
ENST00000538883.1
ENST00000361981.3
L1 cell adhesion molecule
chr19_+_41725140 5.55 ENST00000359092.3
AXL receptor tyrosine kinase
chr1_-_94374946 5.51 ENST00000370238.3
glutamate-cysteine ligase, modifier subunit
chrX_+_47053208 5.49 ENST00000442035.1
ENST00000457753.1
ENST00000335972.6
ubiquitin-like modifier activating enzyme 1
chr18_+_3247779 5.47 ENST00000578611.1
ENST00000583449.1
myosin, light chain 12A, regulatory, non-sarcomeric
chr19_-_1568057 5.47 ENST00000402693.4
ENST00000388824.6
mex-3 RNA binding family member D
chr2_+_238395879 5.45 ENST00000445024.2
ENST00000338530.4
ENST00000409373.1
melanophilin
chr22_-_43036607 5.44 ENST00000505920.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr1_-_86174065 5.41 ENST00000370574.3
ENST00000431532.2
zinc finger, HIT-type containing 6
chr1_-_32403903 5.39 ENST00000344035.6
ENST00000356536.3
protein tyrosine phosphatase type IVA, member 2
chr14_+_105331596 5.38 ENST00000556508.1
ENST00000414716.3
ENST00000453495.1
ENST00000418279.1
centrosomal protein 170B
chr18_+_55888767 5.37 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr1_-_67896095 5.37 ENST00000370994.4
SERPINE1 mRNA binding protein 1
chrX_+_154114635 5.37 ENST00000369446.2
coagulation factor VIII-associated 1
chr12_-_56122426 5.29 ENST00000551173.1
CD63 molecule

Network of associatons between targets according to the STRING database.

First level regulatory network of MESP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
16.9 50.6 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
5.3 26.3 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
5.2 31.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
5.0 19.8 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
4.8 19.3 GO:0021564 vagus nerve development(GO:0021564)
4.5 26.9 GO:0007296 vitellogenesis(GO:0007296)
4.4 13.3 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
4.3 12.8 GO:0021678 fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
3.8 11.4 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
3.8 15.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
3.6 10.8 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
3.6 3.6 GO:0060920 cardiac pacemaker cell differentiation(GO:0060920) cardiac pacemaker cell development(GO:0060926)
3.5 21.1 GO:0048549 positive regulation of pinocytosis(GO:0048549)
3.3 26.8 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
3.3 10.0 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
3.1 9.3 GO:1904693 midbrain morphogenesis(GO:1904693)
3.1 15.3 GO:0003164 His-Purkinje system development(GO:0003164)
2.9 26.4 GO:0006552 leucine catabolic process(GO:0006552)
2.9 8.8 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
2.9 11.5 GO:0046833 snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
2.8 8.5 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
2.8 33.6 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
2.8 11.2 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
2.7 21.3 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) positive regulation of exit from mitosis(GO:0031536)
2.5 7.5 GO:1900060 negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
2.5 12.3 GO:2000542 negative regulation of gastrulation(GO:2000542)
2.4 31.4 GO:0019388 galactose catabolic process(GO:0019388)
2.3 9.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
2.3 13.7 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
2.3 13.6 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
2.2 8.9 GO:0090402 oncogene-induced cell senescence(GO:0090402)
2.2 8.9 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
2.2 11.0 GO:2000784 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
2.1 12.5 GO:0061441 renal artery morphogenesis(GO:0061441)
2.1 6.2 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
2.0 16.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
2.0 6.1 GO:0006566 threonine metabolic process(GO:0006566)
2.0 7.9 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
1.9 30.7 GO:0045793 positive regulation of cell size(GO:0045793)
1.9 5.7 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
1.9 28.3 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
1.9 5.6 GO:1904351 negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
1.9 7.4 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
1.8 16.5 GO:0038007 netrin-activated signaling pathway(GO:0038007)
1.7 14.0 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
1.7 5.2 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
1.7 3.5 GO:0019087 transformation of host cell by virus(GO:0019087)
1.7 5.2 GO:0050894 determination of affect(GO:0050894)
1.6 4.9 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
1.6 3.2 GO:1990637 response to prolactin(GO:1990637)
1.6 10.9 GO:0046836 glycolipid transport(GO:0046836)
1.5 6.1 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
1.5 24.3 GO:0006527 arginine catabolic process(GO:0006527)
1.5 7.5 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
1.5 16.5 GO:0009414 response to water deprivation(GO:0009414)
1.5 5.9 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
1.5 8.8 GO:0030043 actin filament fragmentation(GO:0030043)
1.4 4.1 GO:0032773 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of transforming growth factor beta2 production(GO:0032912) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
1.4 9.6 GO:0090647 modulation of age-related behavioral decline(GO:0090647)
1.3 40.5 GO:0008045 motor neuron axon guidance(GO:0008045)
1.3 6.6 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
1.3 9.1 GO:0021903 rostrocaudal neural tube patterning(GO:0021903)
1.3 6.4 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
1.2 10.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.2 13.9 GO:0006089 lactate metabolic process(GO:0006089)
1.1 3.4 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
1.1 4.6 GO:2000354 regulation of ovarian follicle development(GO:2000354)
1.1 4.5 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
1.1 3.3 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
1.1 18.7 GO:0034063 stress granule assembly(GO:0034063)
1.1 5.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
1.0 13.6 GO:0010668 ectodermal cell differentiation(GO:0010668)
1.0 5.2 GO:0015862 uridine transport(GO:0015862)
1.0 4.1 GO:0032954 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
1.0 16.9 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
1.0 5.9 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
1.0 4.9 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
1.0 12.7 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
1.0 5.9 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.9 9.4 GO:0009415 response to water(GO:0009415)
0.9 4.7 GO:0019348 dolichol metabolic process(GO:0019348)
0.9 2.8 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.9 3.7 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.9 6.5 GO:0009597 detection of virus(GO:0009597)
0.9 4.6 GO:0006041 glucosamine metabolic process(GO:0006041) glucose 1-phosphate metabolic process(GO:0019255)
0.9 5.4 GO:0048254 snoRNA localization(GO:0048254)
0.9 8.9 GO:0007144 female meiosis I(GO:0007144)
0.9 3.6 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
0.9 15.6 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.9 7.7 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.9 9.5 GO:0008298 intracellular mRNA localization(GO:0008298)
0.8 2.5 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.8 3.4 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.8 10.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.8 34.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.8 2.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.8 2.4 GO:2000106 regulation of leukocyte apoptotic process(GO:2000106)
0.8 9.5 GO:0022417 protein maturation by protein folding(GO:0022417)
0.8 8.6 GO:0015868 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.8 1.6 GO:0007497 posterior midgut development(GO:0007497)
0.8 5.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.8 17.5 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.8 6.0 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.7 4.5 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.7 9.7 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.7 12.0 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.7 0.7 GO:1902908 regulation of melanosome transport(GO:1902908)
0.7 17.7 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.7 8.8 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.7 5.1 GO:1900045 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.7 2.1 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.7 2.9 GO:0072423 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.7 7.6 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.7 2.7 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.7 8.1 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.7 49.3 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.6 3.9 GO:0007386 compartment pattern specification(GO:0007386)
0.6 3.2 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.6 7.0 GO:0006621 protein retention in ER lumen(GO:0006621)
0.6 16.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.6 3.1 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.6 3.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.6 2.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.6 24.3 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.6 6.0 GO:0070141 response to UV-A(GO:0070141)
0.6 2.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.6 2.3 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.6 5.3 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.6 2.9 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.6 1.7 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.6 15.1 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.6 2.9 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.6 2.2 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.5 3.3 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.5 2.2 GO:2000035 regulation of stem cell division(GO:2000035)
0.5 13.1 GO:1903077 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.5 1.6 GO:0033005 positive regulation of mast cell activation(GO:0033005)
0.5 1.6 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.5 2.1 GO:0003409 optic cup structural organization(GO:0003409)
0.5 25.2 GO:0048255 mRNA stabilization(GO:0048255)
0.5 2.0 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.5 4.5 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.5 5.0 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.5 2.9 GO:0055064 chloride ion homeostasis(GO:0055064)
0.5 8.6 GO:0097062 dendritic spine maintenance(GO:0097062)
0.5 4.8 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.5 2.9 GO:0034201 response to oleic acid(GO:0034201)
0.5 1.4 GO:1901420 negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
0.5 48.7 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.4 5.7 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.4 4.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.4 7.5 GO:2000637 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.4 9.1 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.4 2.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.4 0.4 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.4 2.9 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.4 5.3 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.4 2.4 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.4 2.8 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.4 2.0 GO:0072244 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.4 5.2 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.4 10.3 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.4 1.2 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.4 17.1 GO:0035329 hippo signaling(GO:0035329)
0.4 9.6 GO:0050873 brown fat cell differentiation(GO:0050873)
0.4 10.4 GO:0042438 melanin biosynthetic process(GO:0042438)
0.4 1.9 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.4 1.9 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.4 0.4 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.4 7.3 GO:0043457 regulation of cellular respiration(GO:0043457)
0.3 5.7 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.3 2.3 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.3 1.6 GO:0009439 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.3 6.8 GO:0003334 keratinocyte development(GO:0003334)
0.3 1.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.3 7.6 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.3 1.2 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.3 1.9 GO:0006177 GMP biosynthetic process(GO:0006177)
0.3 5.8 GO:0016540 protein autoprocessing(GO:0016540)
0.3 2.1 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.3 0.9 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.3 0.9 GO:0006833 water transport(GO:0006833)
0.3 3.2 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.3 0.6 GO:0061743 motor learning(GO:0061743)
0.3 4.0 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.3 4.0 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.3 0.8 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.3 2.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.3 6.4 GO:0006379 mRNA cleavage(GO:0006379)
0.3 1.1 GO:1903826 arginine transmembrane transport(GO:1903826)
0.3 1.3 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.3 2.1 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.3 5.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.2 7.5 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.2 1.2 GO:1904073 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.2 1.9 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.2 13.1 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.2 0.7 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.2 2.1 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.2 2.1 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.2 0.5 GO:0060467 negative regulation of fertilization(GO:0060467)
0.2 1.8 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.2 2.6 GO:0031113 regulation of microtubule polymerization(GO:0031113)
0.2 4.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.2 7.4 GO:0007019 microtubule depolymerization(GO:0007019)
0.2 1.9 GO:0001778 plasma membrane repair(GO:0001778)
0.2 5.7 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.2 0.8 GO:0048733 sebaceous gland development(GO:0048733)
0.2 2.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.2 3.9 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 24.6 GO:0031424 keratinization(GO:0031424)
0.2 13.8 GO:0070126 mitochondrial translational termination(GO:0070126)
0.2 3.8 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.2 3.7 GO:0006415 translational termination(GO:0006415)
0.2 0.6 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.2 0.9 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.2 7.5 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.2 3.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.2 5.7 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.2 1.3 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.2 2.6 GO:0042420 dopamine catabolic process(GO:0042420)
0.2 0.5 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.2 1.5 GO:0035092 sperm chromatin condensation(GO:0035092)
0.2 4.3 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.2 1.1 GO:0072592 oxygen metabolic process(GO:0072592)
0.2 2.7 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.2 9.8 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 3.3 GO:0035455 response to interferon-alpha(GO:0035455)
0.2 7.6 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.2 5.2 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.2 61.2 GO:0043687 post-translational protein modification(GO:0043687)
0.1 3.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 7.3 GO:0030042 actin filament depolymerization(GO:0030042)
0.1 1.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 2.4 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 5.5 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 2.0 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.1 0.5 GO:0070997 neuron death(GO:0070997)
0.1 1.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.5 GO:0035814 negative regulation of urine volume(GO:0035811) negative regulation of renal sodium excretion(GO:0035814)
0.1 2.4 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 1.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 10.5 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 5.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 1.5 GO:0030252 growth hormone secretion(GO:0030252)
0.1 2.1 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.1 4.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.4 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.1 1.5 GO:0008105 asymmetric protein localization(GO:0008105)
0.1 15.0 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.1 0.8 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 0.6 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.1 2.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 4.4 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.1 0.4 GO:0070255 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.1 3.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.9 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.5 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.1 2.6 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.1 0.4 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.1 3.4 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 2.5 GO:0005980 glycogen catabolic process(GO:0005980)
0.1 6.9 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 2.8 GO:0060071 Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.1 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 3.6 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.1 4.3 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 0.7 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 0.8 GO:0051382 kinetochore assembly(GO:0051382)
0.1 2.1 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 2.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 2.8 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 1.6 GO:1901998 toxin transport(GO:1901998)
0.1 3.0 GO:0008347 glial cell migration(GO:0008347)
0.1 1.0 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 4.7 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 11.9 GO:0001649 osteoblast differentiation(GO:0001649)
0.1 1.8 GO:0006310 DNA recombination(GO:0006310)
0.1 14.6 GO:0016042 lipid catabolic process(GO:0016042)
0.1 0.6 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1 0.3 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 2.4 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 2.2 GO:0021766 hippocampus development(GO:0021766)
0.1 1.5 GO:0061512 protein localization to cilium(GO:0061512)
0.0 3.1 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.0 0.3 GO:0014896 cardiac muscle hypertrophy(GO:0003300) muscle hypertrophy(GO:0014896) striated muscle hypertrophy(GO:0014897)
0.0 0.5 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.0 0.7 GO:0032801 receptor catabolic process(GO:0032801)
0.0 1.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.7 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.0 2.2 GO:0002220 innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.8 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.9 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.9 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 1.3 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 1.2 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.3 GO:0007628 adult walking behavior(GO:0007628)
0.0 1.8 GO:0021543 pallium development(GO:0021543)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.5 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.2 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.0 0.6 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.5 GO:0006517 protein deglycosylation(GO:0006517)
0.0 1.9 GO:0006364 rRNA processing(GO:0006364)
0.0 0.2 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.1 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 28.3 GO:0097149 centralspindlin complex(GO:0097149)
5.4 16.3 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
5.3 26.4 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
4.0 28.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
3.9 11.6 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
3.6 50.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
3.5 10.4 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
3.3 13.1 GO:0043260 laminin-11 complex(GO:0043260)
3.1 9.2 GO:0005588 collagen type V trimer(GO:0005588)
2.9 11.5 GO:0005846 nuclear cap binding complex(GO:0005846)
2.6 12.9 GO:0097513 myosin II filament(GO:0097513)
2.5 2.5 GO:0070695 FHF complex(GO:0070695)
2.4 26.7 GO:0005614 interstitial matrix(GO:0005614)
2.1 6.4 GO:0070557 PCNA-p21 complex(GO:0070557)
2.0 24.0 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
1.9 9.5 GO:1990425 ryanodine receptor complex(GO:1990425)
1.9 7.5 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
1.8 34.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
1.6 4.7 GO:1990393 3M complex(GO:1990393)
1.4 8.6 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
1.4 5.6 GO:0031166 integral component of vacuolar membrane(GO:0031166)
1.4 16.3 GO:0005915 zonula adherens(GO:0005915)
1.3 6.3 GO:0071986 Ragulator complex(GO:0071986)
1.3 8.8 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
1.3 11.3 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
1.2 6.2 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
1.2 11.0 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
1.2 53.9 GO:0045095 keratin filament(GO:0045095)
1.2 35.4 GO:0005680 anaphase-promoting complex(GO:0005680)
1.1 5.7 GO:0045323 interleukin-1 receptor complex(GO:0045323)
1.1 3.4 GO:0002081 outer acrosomal membrane(GO:0002081)
1.1 4.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
1.1 7.6 GO:0070852 cell body fiber(GO:0070852)
1.1 3.2 GO:1990015 mesaxon(GO:0097453) ensheathing process(GO:1990015)
1.0 2.1 GO:0005826 actomyosin contractile ring(GO:0005826)
1.0 2.0 GO:0031143 pseudopodium(GO:0031143)
1.0 13.7 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
1.0 14.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
1.0 5.8 GO:0008537 proteasome activator complex(GO:0008537)
0.9 7.5 GO:0005683 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.9 11.4 GO:0033643 host cell part(GO:0033643)
0.9 5.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.8 4.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.8 2.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.8 10.5 GO:0042555 MCM complex(GO:0042555)
0.8 8.9 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.8 4.0 GO:0030905 retromer, tubulation complex(GO:0030905)
0.8 3.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.8 4.7 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.8 2.3 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.8 3.8 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.7 4.5 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.7 7.8 GO:0097443 sorting endosome(GO:0097443)
0.7 23.8 GO:0032420 stereocilium(GO:0032420)
0.7 5.4 GO:0070761 pre-snoRNP complex(GO:0070761)
0.6 8.0 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.6 3.9 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.5 4.8 GO:0072546 ER membrane protein complex(GO:0072546)
0.5 2.6 GO:0030891 VCB complex(GO:0030891)
0.5 3.1 GO:0061689 tricellular tight junction(GO:0061689)
0.5 28.3 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.5 14.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.5 7.5 GO:0031088 platelet dense granule membrane(GO:0031088)
0.5 2.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.5 11.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.4 8.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540) cytosolic proteasome complex(GO:0031597)
0.4 7.3 GO:0030056 hemidesmosome(GO:0030056)
0.4 3.4 GO:0071438 invadopodium membrane(GO:0071438)
0.4 10.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.4 12.6 GO:0030057 desmosome(GO:0030057)
0.4 10.9 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.4 5.9 GO:0005869 dynactin complex(GO:0005869)
0.4 21.7 GO:0005876 spindle microtubule(GO:0005876)
0.4 2.6 GO:0033269 internode region of axon(GO:0033269)
0.4 5.0 GO:0005833 hemoglobin complex(GO:0005833)
0.4 2.8 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.3 26.3 GO:0042734 presynaptic membrane(GO:0042734)
0.3 4.1 GO:0005642 annulate lamellae(GO:0005642)
0.3 0.7 GO:0032039 integrator complex(GO:0032039)
0.3 4.5 GO:0031209 SCAR complex(GO:0031209)
0.3 5.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.3 1.2 GO:0032044 DSIF complex(GO:0032044)
0.3 2.3 GO:0035253 ciliary rootlet(GO:0035253)
0.3 4.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.3 5.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.3 25.2 GO:0043195 terminal bouton(GO:0043195)
0.3 11.2 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.3 5.4 GO:0044295 axonal growth cone(GO:0044295)
0.3 7.4 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.3 2.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.3 8.0 GO:0042101 T cell receptor complex(GO:0042101)
0.2 3.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 5.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.2 2.1 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.2 2.8 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.2 2.3 GO:0032585 multivesicular body membrane(GO:0032585)
0.2 5.2 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.2 6.1 GO:0001533 cornified envelope(GO:0001533)
0.2 2.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 20.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.2 10.5 GO:0002102 podosome(GO:0002102)
0.2 7.4 GO:0031941 filamentous actin(GO:0031941)
0.2 3.8 GO:0097225 sperm midpiece(GO:0097225)
0.2 17.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2 1.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.2 5.7 GO:0005921 gap junction(GO:0005921)
0.2 1.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.2 4.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 9.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.2 6.9 GO:0090544 BAF-type complex(GO:0090544)
0.2 11.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 2.1 GO:0030008 TRAPP complex(GO:0030008)
0.2 1.2 GO:0072487 MSL complex(GO:0072487)
0.2 1.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.2 4.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 1.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 8.5 GO:0005844 polysome(GO:0005844)
0.2 8.3 GO:0035577 azurophil granule membrane(GO:0035577)
0.2 4.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 23.8 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1 19.2 GO:0000922 spindle pole(GO:0000922)
0.1 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 11.8 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 1.8 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 6.9 GO:0015629 actin cytoskeleton(GO:0015629)
0.1 10.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 3.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 2.9 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 2.1 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.5 GO:0005771 multivesicular body(GO:0005771)
0.1 1.5 GO:0005875 microtubule associated complex(GO:0005875)
0.1 5.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 2.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.4 GO:0043196 varicosity(GO:0043196)
0.1 14.3 GO:0043197 dendritic spine(GO:0043197)
0.1 2.3 GO:0031430 M band(GO:0031430)
0.1 4.5 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 10.5 GO:0043204 perikaryon(GO:0043204)
0.1 2.8 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 2.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 2.5 GO:0032040 small-subunit processome(GO:0032040)
0.1 0.7 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 2.2 GO:0000421 autophagosome membrane(GO:0000421)
0.1 3.5 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 6.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 4.7 GO:0005795 Golgi stack(GO:0005795)
0.1 7.1 GO:0001650 fibrillar center(GO:0001650)
0.1 1.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 3.1 GO:0035097 histone methyltransferase complex(GO:0035097)
0.1 4.7 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 8.9 GO:0005819 spindle(GO:0005819)
0.1 1.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 0.6 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 33.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 8.9 GO:0005925 focal adhesion(GO:0005925)
0.0 3.2 GO:0036064 ciliary basal body(GO:0036064)
0.0 3.3 GO:0055037 recycling endosome(GO:0055037)
0.0 96.3 GO:0070062 extracellular exosome(GO:0070062)
0.0 4.5 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 2.5 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 2.4 GO:0005840 ribosome(GO:0005840)
0.0 0.7 GO:0005871 kinesin complex(GO:0005871)
0.0 0.8 GO:0005912 adherens junction(GO:0005912)
0.0 0.1 GO:0031105 septin complex(GO:0031105)
0.0 1.2 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.2 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
16.9 50.6 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
10.5 31.4 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
6.8 34.0 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
5.3 26.4 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
5.0 19.8 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
4.9 24.3 GO:0016403 dimethylargininase activity(GO:0016403)
3.8 11.4 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
3.3 16.3 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
3.0 12.1 GO:0005046 KDEL sequence binding(GO:0005046)
2.7 10.9 GO:0017089 glycolipid transporter activity(GO:0017089)
2.7 10.8 GO:0016842 amidine-lyase activity(GO:0016842)
2.6 7.8 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
2.2 15.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
2.1 6.4 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
2.0 8.1 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
2.0 13.9 GO:0004459 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
2.0 5.9 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
1.9 5.7 GO:0048030 disaccharide binding(GO:0048030)
1.7 3.5 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
1.7 5.2 GO:0031877 somatostatin receptor binding(GO:0031877)
1.7 15.0 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
1.6 4.7 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
1.5 15.3 GO:0051425 PTB domain binding(GO:0051425)
1.5 4.5 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
1.5 25.2 GO:0008494 translation activator activity(GO:0008494)
1.5 7.3 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
1.4 11.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
1.3 5.4 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
1.2 5.0 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
1.2 3.6 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
1.2 6.0 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
1.2 32.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
1.2 4.7 GO:0048763 HLH domain binding(GO:0043398) calcium-induced calcium release activity(GO:0048763)
1.2 3.5 GO:0032427 GBD domain binding(GO:0032427)
1.1 3.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
1.1 3.4 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
1.1 3.3 GO:0004730 pseudouridylate synthase activity(GO:0004730)
1.1 43.8 GO:0003785 actin monomer binding(GO:0003785)
1.1 22.8 GO:0035497 cAMP response element binding(GO:0035497)
1.1 6.3 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
1.1 48.4 GO:0061650 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
1.0 5.2 GO:0070404 NADH binding(GO:0070404)
1.0 6.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
1.0 12.8 GO:0038132 neuregulin binding(GO:0038132)
1.0 16.5 GO:0008432 JUN kinase binding(GO:0008432)
0.9 2.8 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.9 5.6 GO:1903135 cupric ion binding(GO:1903135)
0.9 14.9 GO:0032036 myosin heavy chain binding(GO:0032036)
0.9 7.4 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.9 2.8 GO:0001069 regulatory region RNA binding(GO:0001069)
0.9 3.5 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.9 7.8 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.9 12.0 GO:0017049 GTP-Rho binding(GO:0017049)
0.9 8.5 GO:0045545 syndecan binding(GO:0045545)
0.8 5.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.8 4.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.8 9.1 GO:0004576 oligosaccharyl transferase activity(GO:0004576)
0.8 2.5 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.8 10.7 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.8 5.7 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.8 4.0 GO:1990460 leptin receptor binding(GO:1990460)
0.8 24.0 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.8 3.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.8 4.6 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.8 6.1 GO:0015216 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
0.8 17.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.7 4.5 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.7 7.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.7 2.1 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.7 8.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.7 2.9 GO:0038025 glycoprotein transporter activity(GO:0034437) reelin receptor activity(GO:0038025)
0.7 20.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.7 9.5 GO:0019855 calcium channel inhibitor activity(GO:0019855) type I transforming growth factor beta receptor binding(GO:0034713)
0.7 4.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.7 5.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.7 9.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.6 5.7 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.6 32.1 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.6 8.9 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.6 2.3 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.6 2.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.6 2.3 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.6 4.0 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.6 2.9 GO:0048256 flap endonuclease activity(GO:0048256)
0.6 2.2 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.5 6.5 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.5 10.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.5 1.6 GO:0004962 endothelin receptor activity(GO:0004962)
0.5 5.6 GO:0033592 RNA strand annealing activity(GO:0033592)
0.5 11.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.5 1.9 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.5 7.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.4 1.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.4 3.6 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.4 7.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.4 20.0 GO:0019894 kinesin binding(GO:0019894)
0.4 37.6 GO:0017048 Rho GTPase binding(GO:0017048)
0.4 3.8 GO:0032190 acrosin binding(GO:0032190)
0.4 5.0 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.4 1.2 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.4 2.8 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.4 2.4 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.4 5.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.4 3.8 GO:0001055 RNA polymerase II activity(GO:0001055)
0.4 7.4 GO:0001968 fibronectin binding(GO:0001968)
0.4 5.1 GO:0003680 AT DNA binding(GO:0003680)
0.4 5.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.4 5.5 GO:0017091 AU-rich element binding(GO:0017091)
0.4 7.3 GO:0070628 proteasome binding(GO:0070628)
0.4 5.4 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.4 7.5 GO:0031404 chloride ion binding(GO:0031404)
0.3 8.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 2.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.3 12.2 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.3 6.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.3 2.5 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.3 8.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3 3.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.3 3.0 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.3 3.3 GO:0051434 BH3 domain binding(GO:0051434)
0.3 6.4 GO:0008242 omega peptidase activity(GO:0008242)
0.3 0.8 GO:0070984 SET domain binding(GO:0070984)
0.3 7.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.3 1.9 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.3 4.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.3 1.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.3 13.1 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.3 1.6 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.3 6.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.3 1.3 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.3 4.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) dynein intermediate chain binding(GO:0045505)
0.3 2.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.3 6.1 GO:0008301 DNA binding, bending(GO:0008301)
0.2 2.7 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273) NFAT protein binding(GO:0051525)
0.2 7.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 1.2 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.2 3.3 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 4.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 10.0 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.2 3.2 GO:0033691 sialic acid binding(GO:0033691)
0.2 5.0 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 0.9 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.2 0.4 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.2 2.0 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 11.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.2 5.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.2 17.5 GO:0030295 protein kinase activator activity(GO:0030295)
0.2 8.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 17.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 12.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 3.1 GO:0005243 gap junction channel activity(GO:0005243)
0.2 2.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 0.8 GO:0017040 ceramidase activity(GO:0017040)
0.2 4.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 6.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.2 0.6 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.2 1.1 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.2 2.9 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 5.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 2.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 11.3 GO:0032947 protein complex scaffold(GO:0032947)
0.2 2.4 GO:0016918 retinal binding(GO:0016918)
0.2 0.5 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.2 5.6 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.2 3.5 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.2 3.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.9 GO:0015250 water channel activity(GO:0015250)
0.1 4.9 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 5.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 2.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.9 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 4.9 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 2.0 GO:0070840 dynein complex binding(GO:0070840)
0.1 5.0 GO:0097110 scaffold protein binding(GO:0097110)
0.1 8.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.5 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.1 2.1 GO:0005523 tropomyosin binding(GO:0005523)
0.1 2.0 GO:0005112 Notch binding(GO:0005112)
0.1 3.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 1.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 1.2 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.1 1.6 GO:0017166 vinculin binding(GO:0017166)
0.1 6.4 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.1 3.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 3.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 2.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 3.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 3.6 GO:0042605 peptide antigen binding(GO:0042605)
0.1 31.2 GO:0003924 GTPase activity(GO:0003924)
0.1 2.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 4.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 1.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 4.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 10.7 GO:0005178 integrin binding(GO:0005178)
0.1 10.1 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 10.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 13.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.9 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 8.1 GO:0044325 ion channel binding(GO:0044325)
0.1 8.3 GO:0008201 heparin binding(GO:0008201)
0.1 0.6 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1 0.7 GO:0035240 dopamine binding(GO:0035240)
0.1 1.6 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.7 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 4.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.6 GO:0000150 recombinase activity(GO:0000150)
0.0 2.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.5 GO:0031386 protein tag(GO:0031386)
0.0 2.2 GO:0070888 E-box binding(GO:0070888)
0.0 1.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 2.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 2.7 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 3.5 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.9 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.2 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 2.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.9 GO:0005518 collagen binding(GO:0005518)
0.0 1.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.7 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 1.3 GO:0005525 GTP binding(GO:0005525)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 50.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
1.2 43.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
1.0 23.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
1.0 41.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.9 51.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.8 0.8 ST GAQ PATHWAY G alpha q Pathway
0.7 24.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.7 8.9 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.6 24.0 PID NECTIN PATHWAY Nectin adhesion pathway
0.6 4.0 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.6 15.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.5 19.9 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.5 31.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.5 28.3 PID PLK1 PATHWAY PLK1 signaling events
0.5 10.4 PID REELIN PATHWAY Reelin signaling pathway
0.4 8.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.4 6.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.4 24.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.4 11.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.3 4.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.3 5.5 PID ALK2 PATHWAY ALK2 signaling events
0.3 19.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.3 42.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.3 5.3 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.3 3.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.3 23.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.3 7.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.3 10.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.3 6.2 PID ARF 3PATHWAY Arf1 pathway
0.2 8.0 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.2 6.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 8.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.2 8.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.2 5.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 4.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.2 2.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 6.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.2 10.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 3.6 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.1 1.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 5.7 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 8.3 PID NOTCH PATHWAY Notch signaling pathway
0.1 4.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 6.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 1.9 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 3.2 PID ATR PATHWAY ATR signaling pathway
0.1 4.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 4.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 2.5 PID ATM PATHWAY ATM pathway
0.1 3.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 1.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 3.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.1 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 0.8 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.4 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.7 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 9.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 3.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 66.5 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
1.7 31.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
1.3 35.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
1.2 18.9 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
1.0 19.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
1.0 8.9 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
1.0 41.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
1.0 26.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
1.0 27.0 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.9 37.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.9 17.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.8 28.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.8 16.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.7 12.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.7 26.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.7 36.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.7 26.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.7 19.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.7 10.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.7 9.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.7 51.7 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.7 11.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.7 20.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.7 10.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.6 17.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.6 12.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.6 12.8 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.5 11.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.5 10.6 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.5 11.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.5 5.7 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.5 12.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.4 8.9 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.4 6.4 REACTOME ORC1 REMOVAL FROM CHROMATIN Genes involved in Orc1 removal from chromatin
0.4 32.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.4 16.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.3 24.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.3 14.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.3 2.5 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.3 8.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3 3.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.3 13.0 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2 1.7 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.2 6.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 4.5 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 6.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.2 5.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.2 8.0 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.2 6.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 5.7 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.2 1.6 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.2 5.9 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.2 2.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 21.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.2 4.0 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.2 4.5 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.2 3.7 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.2 2.3 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.2 5.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 2.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.2 17.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 4.4 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 10.8 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 2.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 3.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 9.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 16.6 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1 2.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 2.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 4.9 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 2.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 4.1 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 6.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 2.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 3.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 4.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 8.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 2.1 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.1 7.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 4.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 8.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.9 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.3 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 1.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 8.6 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 2.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.1 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 1.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling