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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for MLX_USF2_USF1_PAX2

Z-value: 0.60

Motif logo

Transcription factors associated with MLX_USF2_USF1_PAX2

Gene Symbol Gene ID Gene Info
ENSG00000108788.7 MAX dimerization protein MLX
ENSG00000105698.11 upstream transcription factor 2, c-fos interacting
ENSG00000158773.10 upstream transcription factor 1
ENSG00000075891.17 paired box 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
USF2hg19_v2_chr19_+_35759824_357598910.338.5e-07Click!
MLXhg19_v2_chr17_+_40719073_407190920.111.0e-01Click!
PAX2hg19_v2_chr10_+_102505468_1025055460.063.6e-01Click!

Activity profile of MLX_USF2_USF1_PAX2 motif

Sorted Z-values of MLX_USF2_USF1_PAX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_10764509 47.11 ENST00000591501.1
ILF3 antisense RNA 1 (head to head)
chr1_+_11866270 38.71 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
chloride channel, voltage-sensitive 6
chr13_+_113951607 35.57 ENST00000397181.3
lysosomal-associated membrane protein 1
chr19_+_1067144 29.60 ENST00000313093.2
histocompatibility (minor) HA-1
chr19_+_1067492 29.43 ENST00000586866.1
histocompatibility (minor) HA-1
chr1_+_11866207 29.28 ENST00000312413.6
ENST00000346436.6
chloride channel, voltage-sensitive 6
chr19_+_1067271 29.18 ENST00000536472.1
ENST00000590214.1
histocompatibility (minor) HA-1
chr11_+_121322832 28.03 ENST00000260197.7
sortilin-related receptor, L(DLR class) A repeats containing
chr19_+_10765003 27.40 ENST00000407004.3
ENST00000589998.1
ENST00000589600.1
interleukin enhancer binding factor 3, 90kDa
chr6_-_33385902 27.28 ENST00000374500.5
cutA divalent cation tolerance homolog (E. coli)
chr1_-_241520525 26.20 ENST00000366565.1
regulator of G-protein signaling 7
chr17_-_35969409 24.54 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
synergin, gamma
chr16_-_15736953 23.98 ENST00000548025.1
ENST00000551742.1
ENST00000602337.1
ENST00000344181.3
ENST00000396368.3
KIAA0430
chr6_-_33385870 23.78 ENST00000488034.1
cutA divalent cation tolerance homolog (E. coli)
chr13_+_113951532 23.60 ENST00000332556.4
lysosomal-associated membrane protein 1
chrX_+_128913906 23.16 ENST00000356892.3
SAM and SH3 domain containing 3
chr6_-_33385655 22.82 ENST00000440279.3
ENST00000607266.1
cutA divalent cation tolerance homolog (E. coli)
chr5_-_172198190 22.45 ENST00000239223.3
dual specificity phosphatase 1
chr16_+_85061367 21.82 ENST00000538274.1
ENST00000258180.3
KIAA0513
chr17_-_76124711 21.68 ENST00000306591.7
ENST00000590602.1
transmembrane channel-like 6
chr6_-_33385823 21.64 ENST00000494751.1
ENST00000374496.3
cutA divalent cation tolerance homolog (E. coli)
chr10_+_46222648 21.17 ENST00000336378.4
ENST00000540872.1
ENST00000537517.1
ENST00000374362.2
ENST00000359860.4
ENST00000420848.1
family with sequence similarity 21, member C
chrX_+_102469997 21.17 ENST00000372695.5
ENST00000372691.3
brain expressed, X-linked 4
chr1_-_241520385 20.88 ENST00000366564.1
regulator of G-protein signaling 7
chr9_+_6757634 20.73 ENST00000543771.1
ENST00000401787.3
ENST00000381306.3
ENST00000381309.3
lysine (K)-specific demethylase 4C
chr6_-_33385854 20.22 ENST00000488478.1
cutA divalent cation tolerance homolog (E. coli)
chr18_+_32556892 19.82 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
microtubule-associated protein, RP/EB family, member 2
chr10_+_51827648 19.04 ENST00000351071.6
ENST00000314664.7
ENST00000282633.5
family with sequence similarity 21, member A
chr17_-_76124812 18.95 ENST00000592063.1
ENST00000589271.1
ENST00000322933.4
ENST00000589553.1
transmembrane channel-like 6
chr1_-_11865982 18.52 ENST00000418034.1
methylenetetrahydrofolate reductase (NAD(P)H)
chr20_+_44519948 18.51 ENST00000354880.5
ENST00000191018.5
cathepsin A
chr3_+_158519654 18.05 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
major facilitator superfamily domain containing 1
chr12_-_76953573 18.02 ENST00000549646.1
ENST00000550628.1
ENST00000553139.1
ENST00000261183.3
ENST00000393250.4
oxysterol binding protein-like 8
chr1_-_11866034 18.00 ENST00000376590.3
methylenetetrahydrofolate reductase (NAD(P)H)
chr20_+_2821340 17.96 ENST00000380445.3
ENST00000380469.3
vacuolar protein sorting 16 homolog (S. cerevisiae)
chr1_-_154193009 17.89 ENST00000368518.1
ENST00000368519.1
ENST00000368521.5
chromosome 1 open reading frame 43
chr20_+_44520009 17.78 ENST00000607482.1
ENST00000372459.2
cathepsin A
chr16_-_88923285 17.72 ENST00000542788.1
ENST00000569433.1
ENST00000268695.5
ENST00000568311.1
galactosamine (N-acetyl)-6-sulfate sulfatase
chr14_-_20923195 17.21 ENST00000206542.4
O-sialoglycoprotein endopeptidase
chr11_-_116968987 16.92 ENST00000434315.2
ENST00000292055.4
ENST00000375288.1
ENST00000542607.1
ENST00000445177.1
ENST00000375300.1
ENST00000446921.2
SIK family kinase 3
chr16_-_1525016 16.70 ENST00000262318.8
ENST00000448525.1
chloride channel, voltage-sensitive 7
chrX_+_100663243 16.64 ENST00000316594.5
heterogeneous nuclear ribonucleoprotein H2 (H')
chr8_-_54755789 16.16 ENST00000359530.2
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr21_+_38445539 16.10 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
tetratricopeptide repeat domain 3
chr19_-_48018203 16.02 ENST00000595227.1
ENST00000593761.1
ENST00000263354.3
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr9_-_123476612 15.69 ENST00000426959.1
multiple EGF-like-domains 9
chr2_-_136875712 15.67 ENST00000241393.3
chemokine (C-X-C motif) receptor 4
chr6_-_99873145 15.41 ENST00000369239.5
ENST00000438806.1
PNN-interacting serine/arginine-rich protein
chr11_-_6640585 15.37 ENST00000533371.1
ENST00000528657.1
ENST00000436873.2
ENST00000299427.6
tripeptidyl peptidase I
chr12_+_28343365 15.30 ENST00000545336.1
coiled-coil domain containing 91
chr13_+_42846272 15.27 ENST00000025301.2
A kinase (PRKA) anchor protein 11
chrX_-_13835147 15.23 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chr11_+_118938485 15.01 ENST00000300793.6
vacuolar protein sorting 11 homolog (S. cerevisiae)
chr12_-_109027643 14.92 ENST00000388962.3
ENST00000550948.1
selectin P ligand
chr6_+_138188551 14.82 ENST00000237289.4
ENST00000433680.1
tumor necrosis factor, alpha-induced protein 3
chr5_-_131132658 14.70 ENST00000514667.1
ENST00000511848.1
ENST00000510461.1
Folliculin-interacting protein 1
folliculin interacting protein 1
chr9_-_123476719 14.62 ENST00000373930.3
multiple EGF-like-domains 9
chr3_+_112280857 14.49 ENST00000492406.1
ENST00000468642.1
solute carrier family 35, member A5
chr3_-_122512619 13.96 ENST00000383659.1
ENST00000306103.2
HSPB (heat shock 27kDa) associated protein 1
chr16_-_5083917 13.91 ENST00000312251.3
ENST00000381955.3
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr1_+_110162448 13.91 ENST00000342115.4
ENST00000469039.2
ENST00000474459.1
ENST00000528667.1
adenosine monophosphate deaminase 2
chr3_+_113465866 13.86 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr16_-_5083589 13.57 ENST00000563578.1
ENST00000562346.2
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr12_+_51633061 13.12 ENST00000551313.1
DAZ associated protein 2
chr18_+_9136758 13.10 ENST00000383440.2
ENST00000262126.4
ENST00000577992.1
ankyrin repeat domain 12
chr15_+_44084040 13.09 ENST00000249786.4
small EDRK-rich factor 2
chr12_+_51632508 13.07 ENST00000449723.3
DAZ associated protein 2
chr19_-_49137790 13.05 ENST00000599385.1
D site of albumin promoter (albumin D-box) binding protein
chr12_-_110434096 12.87 ENST00000320063.9
ENST00000457474.2
ENST00000547815.1
ENST00000361006.5
G protein-coupled receptor kinase interacting ArfGAP 2
chr22_+_35695793 12.72 ENST00000456128.1
ENST00000449058.2
ENST00000411850.1
ENST00000425375.1
ENST00000436462.2
ENST00000382034.5
target of myb1 (chicken)
chr8_-_54755459 12.72 ENST00000524234.1
ENST00000521275.1
ENST00000396774.2
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr14_-_74551096 12.54 ENST00000350259.4
aldehyde dehydrogenase 6 family, member A1
chr8_+_71581565 12.47 ENST00000408926.3
ENST00000520030.1
XK, Kell blood group complex subunit-related family, member 9
chr19_-_49137762 12.38 ENST00000593500.1
D site of albumin promoter (albumin D-box) binding protein
chr12_-_65153175 12.37 ENST00000543646.1
ENST00000542058.1
ENST00000258145.3
glucosamine (N-acetyl)-6-sulfatase
chr19_+_40854559 12.25 ENST00000598962.1
ENST00000409419.1
ENST00000409587.1
ENST00000602131.1
ENST00000409735.4
ENST00000600948.1
ENST00000356508.5
ENST00000596682.1
ENST00000594908.1
phospholipase D family, member 3
chr6_-_36953833 12.17 ENST00000538808.1
ENST00000460219.1
ENST00000373616.5
ENST00000373627.5
mitochondrial carrier 1
chr9_-_100684845 12.13 ENST00000375119.3
chromosome 9 open reading frame 156
chr12_+_51632638 12.10 ENST00000549732.2
DAZ associated protein 2
chr16_+_2570340 12.02 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
amidohydrolase domain containing 2
chr2_-_220042825 12.01 ENST00000409789.1
cyclin Pas1/PHO80 domain containing 1
chr14_+_24630465 11.98 ENST00000557894.1
ENST00000559284.1
ENST00000560275.1
interferon regulatory factor 9
chr18_+_32621324 11.90 ENST00000300249.5
ENST00000538170.2
ENST00000588910.1
microtubule-associated protein, RP/EB family, member 2
chr18_-_29522989 11.83 ENST00000582539.1
ENST00000283351.4
ENST00000582513.1
trafficking protein particle complex 8
chr2_-_198299726 11.68 ENST00000409915.4
ENST00000487698.1
ENST00000414963.2
ENST00000335508.6
splicing factor 3b, subunit 1, 155kDa
chr2_-_197036289 11.60 ENST00000263955.4
serine/threonine kinase 17b
chr14_+_64970662 11.58 ENST00000556965.1
ENST00000554015.1
zinc finger and BTB domain containing 1
chr16_+_31044812 11.56 ENST00000313843.3
syntaxin 4
chr17_-_7137582 11.35 ENST00000575756.1
ENST00000575458.1
dishevelled segment polarity protein 2
chr12_+_56110247 11.22 ENST00000551926.1
biogenesis of lysosomal organelles complex-1, subunit 1
chr16_-_4466622 11.21 ENST00000570645.1
ENST00000574025.1
ENST00000572898.1
ENST00000537233.2
ENST00000571059.1
ENST00000251166.4
coronin 7
chr2_+_220042933 11.16 ENST00000430297.2
family with sequence similarity 134, member A
chr17_+_65821636 11.15 ENST00000544778.2
bromodomain PHD finger transcription factor
chr16_+_15737124 11.06 ENST00000396355.1
ENST00000396353.2
nudE neurodevelopment protein 1
chr12_-_76953284 11.00 ENST00000547544.1
ENST00000393249.2
oxysterol binding protein-like 8
chr11_-_72463421 10.90 ENST00000393609.3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr12_-_110434183 10.81 ENST00000360185.4
ENST00000354574.4
ENST00000338373.5
ENST00000343646.5
ENST00000356259.4
ENST00000553118.1
G protein-coupled receptor kinase interacting ArfGAP 2
chrX_-_106960285 10.81 ENST00000503515.1
ENST00000372397.2
TSC22 domain family, member 3
chr12_+_51632600 10.73 ENST00000549555.1
ENST00000439799.2
ENST00000425012.2
DAZ associated protein 2
chr1_-_154531095 10.69 ENST00000292211.4
ubiquitin-conjugating enzyme E2Q family member 1
chr22_-_39268192 10.48 ENST00000216083.6
chromobox homolog 6
chr10_-_3827371 10.44 ENST00000469435.1
Kruppel-like factor 6
chr10_-_3827417 9.91 ENST00000497571.1
ENST00000542957.1
Kruppel-like factor 6
chr5_+_139493665 9.88 ENST00000331327.3
purine-rich element binding protein A
chr19_-_51875894 9.85 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
natural killer cell group 7 sequence
chr16_+_31044413 9.81 ENST00000394998.1
syntaxin 4
chr16_-_4897266 9.79 ENST00000591451.1
ENST00000436648.5
ENST00000381983.3
ENST00000588297.1
ENST00000321919.9
glyoxylate reductase 1 homolog (Arabidopsis)
chr7_+_106685079 9.60 ENST00000265717.4
protein kinase, cAMP-dependent, regulatory, type II, beta
chr1_+_9599540 9.55 ENST00000302692.6
solute carrier family 25 (pyrimidine nucleotide carrier), member 33
chr12_+_7023735 9.39 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
enolase 2 (gamma, neuronal)
chr16_-_57219966 9.32 ENST00000565760.1
ENST00000309137.8
ENST00000570184.1
ENST00000562324.1
family with sequence similarity 192, member A
chr12_+_7023491 9.25 ENST00000541477.1
ENST00000229277.1
enolase 2 (gamma, neuronal)
chr15_-_72668185 9.12 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
hexosaminidase A (alpha polypeptide)
chrX_+_101380642 9.12 ENST00000372780.1
ENST00000329035.2
transcription elongation factor A (SII)-like 2
chr15_+_44084503 9.10 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
small EDRK-rich factor 2
chr5_-_175964366 9.10 ENST00000274811.4
ring finger protein 44
chr16_-_28503327 8.98 ENST00000535392.1
ENST00000395653.4
ceroid-lipofuscinosis, neuronal 3
chr12_+_105501487 8.83 ENST00000332180.5
KIAA1033
chr19_+_7587491 8.75 ENST00000264079.6
mucolipin 1
chr12_-_110434021 8.75 ENST00000355312.3
ENST00000551209.1
ENST00000550186.1
G protein-coupled receptor kinase interacting ArfGAP 2
chr6_+_127587755 8.62 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
ring finger protein 146
chr3_-_48057890 8.61 ENST00000434267.1
microtubule-associated protein 4
chr14_-_64970494 8.54 ENST00000608382.1
zinc finger and BTB domain containing 25
chr19_-_5340730 8.48 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
protein tyrosine phosphatase, receptor type, S
chr6_+_32811885 8.46 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAP1 and PSMB8 antisense RNA 1
proteasome (prosome, macropain) subunit, beta type, 9
chr14_-_74551172 8.42 ENST00000553458.1
aldehyde dehydrogenase 6 family, member A1
chr19_+_5681011 8.38 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
hydroxysteroid (11-beta) dehydrogenase 1-like
chr18_+_21083437 8.37 ENST00000269221.3
ENST00000590868.1
ENST00000592119.1
chromosome 18 open reading frame 8
chr9_-_79307096 8.34 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
prune homolog 2 (Drosophila)
chr18_+_9708162 8.30 ENST00000578921.1
RAB31, member RAS oncogene family
chr6_+_139456226 8.19 ENST00000367658.2
headcase homolog (Drosophila)
chrX_-_15872914 8.18 ENST00000380291.1
ENST00000545766.1
ENST00000421527.2
ENST00000329235.2
adaptor-related protein complex 1, sigma 2 subunit
chr14_-_93651186 8.18 ENST00000556883.1
ENST00000298894.4
modulator of apoptosis 1
chr5_+_150827143 8.17 ENST00000243389.3
ENST00000517945.1
ENST00000521925.1
solute carrier family 36 (proton/amino acid symporter), member 1
chrX_-_13835461 8.14 ENST00000316715.4
ENST00000356942.5
glycoprotein M6B
chr11_-_85779786 8.07 ENST00000356360.5
phosphatidylinositol binding clathrin assembly protein
chr1_+_42922173 7.98 ENST00000455780.1
ENST00000372560.3
ENST00000372561.3
ENST00000372556.3
phosphopantothenoylcysteine synthetase
chr12_-_90102594 7.97 ENST00000428670.3
ATPase, Ca++ transporting, plasma membrane 1
chr7_+_97361218 7.88 ENST00000319273.5
tachykinin, precursor 1
chr16_-_28503357 7.86 ENST00000333496.9
ENST00000561505.1
ENST00000567963.1
ENST00000354630.5
ENST00000355477.5
ENST00000357076.5
ENST00000565688.1
ENST00000359984.7
ceroid-lipofuscinosis, neuronal 3
chr1_-_154928562 7.81 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
pre-B-cell leukemia homeobox interacting protein 1
chr12_-_114404111 7.70 ENST00000545145.2
ENST00000392561.3
ENST00000261741.5
RNA binding motif protein 19
chr8_-_126104055 7.68 ENST00000318410.7
KIAA0196
chr10_-_73611046 7.66 ENST00000394934.1
ENST00000394936.3
prosaposin
chr21_-_38639813 7.65 ENST00000309117.6
ENST00000398998.1
Down syndrome critical region gene 3
chr19_-_51875523 7.60 ENST00000593572.1
ENST00000595157.1
natural killer cell group 7 sequence
chrX_+_100878079 7.60 ENST00000471229.2
armadillo repeat containing, X-linked 3
chr1_+_92414952 7.57 ENST00000449584.1
ENST00000427104.1
ENST00000355011.3
ENST00000448194.1
ENST00000426141.1
ENST00000450792.1
ENST00000548992.1
ENST00000552654.1
ENST00000457265.1
bromodomain, testis-specific
chr6_-_84937314 7.55 ENST00000257766.4
ENST00000403245.3
KIAA1009
chr1_-_111746966 7.49 ENST00000369752.5
DENN/MADD domain containing 2D
chr2_-_136873735 7.46 ENST00000409817.1
chemokine (C-X-C motif) receptor 4
chr16_-_67514982 7.43 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr2_-_47572105 7.41 ENST00000419035.1
ENST00000448713.1
ENST00000450550.1
ENST00000413185.2
AC073283.4
chrX_+_146993534 7.31 ENST00000334557.6
ENST00000439526.2
ENST00000370475.4
fragile X mental retardation 1
chr8_+_94929110 7.30 ENST00000520728.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr17_-_62502399 7.28 ENST00000450599.2
ENST00000585060.1
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr2_-_105946491 7.25 ENST00000393359.2
transforming growth factor, beta receptor associated protein 1
chrX_-_100872911 7.24 ENST00000361910.4
ENST00000539247.1
ENST00000538627.1
armadillo repeat containing, X-linked 6
chr6_+_127588020 7.23 ENST00000309649.3
ENST00000610162.1
ENST00000610153.1
ENST00000608991.1
ENST00000480444.1
ring finger protein 146
chr11_+_65479702 7.14 ENST00000530446.1
ENST00000534104.1
ENST00000530605.1
ENST00000528198.1
ENST00000531880.1
ENST00000534650.1
K(lysine) acetyltransferase 5
chr7_+_99070464 7.12 ENST00000331410.5
ENST00000483089.1
ENST00000448667.1
ENST00000493485.1
zinc finger protein 789
chr22_-_39268308 7.10 ENST00000407418.3
chromobox homolog 6
chr22_-_20850128 7.09 ENST00000328879.4
kelch-like family member 22
chr8_+_94929077 7.09 ENST00000297598.4
ENST00000520614.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr15_-_72668805 7.01 ENST00000268097.5
hexosaminidase A (alpha polypeptide)
chr8_-_126103969 6.99 ENST00000517845.1
KIAA0196
chr6_+_87865262 6.93 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
zinc finger protein 292
chr16_-_28503080 6.93 ENST00000565316.1
ENST00000565778.1
ENST00000357857.9
ENST00000568558.1
ENST00000357806.7
ceroid-lipofuscinosis, neuronal 3
chr3_+_19988566 6.92 ENST00000273047.4
RAB5A, member RAS oncogene family
chr8_+_98656693 6.91 ENST00000519934.1
metadherin
chr5_+_43603229 6.91 ENST00000344920.4
ENST00000512996.2
nicotinamide nucleotide transhydrogenase
chr6_-_109703600 6.87 ENST00000512821.1
CD164 molecule, sialomucin
chr3_-_170626418 6.85 ENST00000474096.1
ENST00000295822.2
eukaryotic translation initiation factor 5A2
chr12_+_56109926 6.83 ENST00000547076.1
biogenesis of lysosomal organelles complex-1, subunit 1
chr17_-_47841485 6.81 ENST00000506156.1
ENST00000240364.2
family with sequence similarity 117, member A
chr20_-_45985172 6.69 ENST00000536340.1
zinc finger, MYND-type containing 8
chr14_+_24583836 6.69 ENST00000559115.1
ENST00000558215.1
ENST00000557810.1
ENST00000561375.1
ENST00000446197.3
ENST00000559796.1
ENST00000560713.1
ENST00000560901.1
ENST00000559382.1
DDB1 and CUL4 associated factor 11
chr9_+_115913222 6.66 ENST00000259392.3
solute carrier family 31 (copper transporter), member 2
chr20_+_34359905 6.66 ENST00000374012.3
ENST00000439301.1
ENST00000339089.6
ENST00000374000.4
PHD finger protein 20
chr8_+_94929168 6.65 ENST00000518107.1
ENST00000396200.3
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr12_+_28343353 6.52 ENST00000539107.1
coiled-coil domain containing 91
chr12_+_12870055 6.49 ENST00000228872.4
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr2_+_30369859 6.47 ENST00000402003.3
yippee-like 5 (Drosophila)
chr6_-_32811771 6.45 ENST00000395339.3
ENST00000374882.3
proteasome (prosome, macropain) subunit, beta type, 8
chr19_-_45681482 6.43 ENST00000592647.1
ENST00000006275.4
ENST00000588062.1
ENST00000585934.1
trafficking protein particle complex 6A
chr7_+_97361388 6.42 ENST00000350485.4
ENST00000346867.4
tachykinin, precursor 1
chr2_+_30369807 6.41 ENST00000379520.3
ENST00000379519.3
ENST00000261353.4
yippee-like 5 (Drosophila)
chr14_-_92572894 6.38 ENST00000532032.1
ENST00000506466.1
ENST00000555381.1
ENST00000557311.1
ENST00000554592.1
ENST00000554672.1
ENST00000553491.1
ENST00000556220.1
ENST00000502250.1
ENST00000503767.1
ENST00000393287.5
ENST00000340660.6
ENST00000545170.1
ENST00000429774.2
ataxin 3
chr22_-_21213029 6.38 ENST00000572273.1
ENST00000255882.6
phosphatidylinositol 4-kinase, catalytic, alpha
chr11_-_85780086 6.36 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
phosphatidylinositol binding clathrin assembly protein
chr11_+_75526212 6.34 ENST00000356136.3
UV radiation resistance associated
chr3_-_98241358 6.31 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
claudin domain containing 1
chr1_-_31712401 6.23 ENST00000373736.2
Na+/K+ transporting ATPase interacting 1
chr11_+_65479462 6.23 ENST00000377046.3
ENST00000352980.4
ENST00000341318.4
K(lysine) acetyltransferase 5
chr1_-_28559502 6.18 ENST00000263697.4
DnaJ (Hsp40) homolog, subfamily C, member 8
chr19_+_10764937 6.15 ENST00000449870.1
ENST00000318511.3
ENST00000420083.1
interleukin enhancer binding factor 3, 90kDa
chr5_+_43602750 6.09 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
nicotinamide nucleotide transhydrogenase
chr1_+_22778337 6.09 ENST00000404138.1
ENST00000400239.2
ENST00000375647.4
ENST00000374651.4
zinc finger and BTB domain containing 40
chr20_-_45985464 6.04 ENST00000458360.2
ENST00000262975.4
zinc finger, MYND-type containing 8
chr20_+_37590942 6.04 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
DEAH (Asp-Glu-Ala-His) box polypeptide 35

Network of associatons between targets according to the STRING database.

First level regulatory network of MLX_USF2_USF1_PAX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
14.8 59.2 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
9.3 28.0 GO:1902997 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
7.3 36.5 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
7.1 21.4 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
6.7 20.1 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
6.4 32.0 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
5.9 23.8 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
5.7 17.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
5.7 17.1 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
5.2 21.0 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
5.1 15.2 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
5.0 14.9 GO:0050902 leukocyte adhesive activation(GO:0050902)
4.8 14.3 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
4.3 38.8 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
4.3 17.1 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
4.2 8.5 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
4.1 29.0 GO:0090204 protein localization to nuclear pore(GO:0090204)
4.1 36.5 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
4.0 11.9 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
3.8 15.4 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
3.6 3.6 GO:0045347 MHC class II biosynthetic process(GO:0045342) regulation of MHC class II biosynthetic process(GO:0045346) negative regulation of MHC class II biosynthetic process(GO:0045347)
3.4 10.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
3.3 26.7 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
3.3 23.1 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
3.2 16.0 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
3.1 31.1 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
3.1 24.7 GO:0060155 platelet dense granule organization(GO:0060155)
3.0 18.1 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
3.0 12.0 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
3.0 8.9 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
3.0 11.8 GO:0030242 pexophagy(GO:0030242)
2.9 11.6 GO:0002572 pro-T cell differentiation(GO:0002572)
2.9 11.5 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
2.7 5.5 GO:1902593 nuclear import(GO:0051170) single-organism nuclear import(GO:1902593)
2.7 21.8 GO:0090160 Golgi to lysosome transport(GO:0090160)
2.6 13.0 GO:0006740 NADPH regeneration(GO:0006740)
2.6 10.3 GO:0015808 L-alanine transport(GO:0015808)
2.6 40.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
2.4 69.7 GO:0006884 cell volume homeostasis(GO:0006884)
2.4 2.4 GO:0015917 aminophospholipid transport(GO:0015917)
2.4 44.9 GO:0042340 keratan sulfate catabolic process(GO:0042340)
2.3 7.0 GO:1900075 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
2.3 13.8 GO:0098535 de novo centriole assembly(GO:0098535)
2.2 13.4 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
2.1 8.6 GO:1902544 oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544)
2.1 6.3 GO:0051684 maintenance of Golgi location(GO:0051684)
2.0 8.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
2.0 6.0 GO:1903028 positive regulation of opsonization(GO:1903028)
2.0 8.0 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
2.0 9.8 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
1.9 9.6 GO:0097338 response to clozapine(GO:0097338)
1.9 62.0 GO:0090383 phagosome acidification(GO:0090383)
1.9 9.3 GO:1903564 regulation of protein localization to cilium(GO:1903564)
1.9 5.6 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
1.9 5.6 GO:0006258 UDP-glucose catabolic process(GO:0006258) galactose catabolic process via UDP-galactose(GO:0033499)
1.8 5.3 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
1.8 5.3 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
1.7 12.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
1.7 13.6 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
1.7 10.2 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
1.7 5.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
1.7 11.6 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
1.7 5.0 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
1.6 3.2 GO:0002384 hepatic immune response(GO:0002384)
1.6 6.4 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
1.6 8.0 GO:1990034 calcium ion export from cell(GO:1990034)
1.6 8.0 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
1.5 4.6 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
1.5 6.1 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
1.5 4.6 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
1.5 4.4 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
1.4 5.8 GO:0000255 allantoin metabolic process(GO:0000255)
1.4 8.6 GO:0051012 microtubule sliding(GO:0051012)
1.4 2.8 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
1.4 4.2 GO:0090149 mitochondrial membrane fission(GO:0090149)
1.4 4.2 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
1.4 5.4 GO:0022027 interkinetic nuclear migration(GO:0022027)
1.4 10.8 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
1.4 4.1 GO:0001207 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
1.3 4.0 GO:0033364 mast cell secretory granule organization(GO:0033364)
1.3 2.7 GO:0030220 platelet formation(GO:0030220)
1.3 4.0 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
1.3 3.9 GO:0071284 cellular response to lead ion(GO:0071284)
1.3 5.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
1.3 3.8 GO:1900368 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
1.3 12.5 GO:0032264 IMP salvage(GO:0032264)
1.2 9.8 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
1.2 7.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
1.2 14.5 GO:0070459 prolactin secretion(GO:0070459)
1.2 23.0 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
1.2 8.1 GO:0090382 phagosome maturation(GO:0090382)
1.1 6.9 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
1.1 8.0 GO:1903715 regulation of aerobic respiration(GO:1903715)
1.1 6.8 GO:0090170 regulation of Golgi inheritance(GO:0090170)
1.1 5.6 GO:0090650 rRNA transport(GO:0051029) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
1.1 4.5 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
1.1 4.5 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
1.1 3.3 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
1.1 3.3 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.1 3.3 GO:0072434 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
1.1 5.5 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
1.1 5.5 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
1.1 3.2 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
1.1 6.4 GO:1903232 melanosome assembly(GO:1903232)
1.1 3.2 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
1.1 3.2 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
1.1 8.4 GO:1901525 negative regulation of macromitophagy(GO:1901525)
1.0 3.1 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
1.0 7.2 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
1.0 4.0 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
1.0 3.0 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
1.0 3.9 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
1.0 2.9 GO:0006014 D-ribose metabolic process(GO:0006014)
1.0 4.8 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
1.0 2.9 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.9 5.6 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.9 6.6 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.9 6.5 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.9 3.7 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.9 12.0 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.9 2.8 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.9 19.9 GO:0006895 Golgi to endosome transport(GO:0006895)
0.9 11.6 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.9 5.3 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.9 3.4 GO:0043335 protein unfolding(GO:0043335)
0.9 5.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.8 5.9 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.8 4.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.8 2.4 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.8 3.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.8 2.4 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.8 2.4 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.8 3.1 GO:0007538 primary sex determination(GO:0007538)
0.8 1.6 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.8 5.4 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.8 2.3 GO:0060915 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.8 4.5 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.7 2.2 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.7 3.0 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.7 1.5 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.7 2.2 GO:0043320 natural killer cell degranulation(GO:0043320)
0.7 5.9 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.7 5.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.7 5.8 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.7 2.2 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.7 13.7 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.7 6.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.7 11.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.7 6.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.7 2.1 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.7 6.3 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.7 1.4 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.7 4.9 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.7 11.1 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.7 19.3 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.7 7.6 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.7 14.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.7 5.5 GO:0051601 exocyst localization(GO:0051601)
0.7 2.7 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.7 2.7 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.7 4.7 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.7 2.7 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.7 0.7 GO:1903056 regulation of melanosome organization(GO:1903056)
0.7 2.0 GO:0039650 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.6 1.3 GO:0010040 response to iron(II) ion(GO:0010040)
0.6 11.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.6 0.6 GO:0061055 myotome development(GO:0061055)
0.6 4.2 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.6 4.2 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884)
0.6 1.8 GO:0010212 response to ionizing radiation(GO:0010212)
0.6 2.9 GO:0036369 transcription factor catabolic process(GO:0036369)
0.6 11.1 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.6 3.5 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.6 2.3 GO:0005985 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986)
0.6 4.6 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.6 5.1 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.6 5.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.6 8.9 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.6 2.2 GO:0044375 regulation of peroxisome size(GO:0044375)
0.5 3.8 GO:0045007 depurination(GO:0045007)
0.5 5.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.5 2.2 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.5 5.9 GO:0046185 aldehyde catabolic process(GO:0046185)
0.5 9.1 GO:0033572 transferrin transport(GO:0033572)
0.5 0.5 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.5 3.2 GO:0019532 oxalate transport(GO:0019532)
0.5 2.1 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.5 2.1 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.5 0.5 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.5 1.0 GO:0046533 negative regulation of photoreceptor cell differentiation(GO:0046533)
0.5 2.5 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.5 1.5 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.5 5.0 GO:1903753 negative regulation of p38MAPK cascade(GO:1903753)
0.5 6.9 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.5 2.4 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.5 1.5 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.5 7.8 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.5 2.9 GO:1901538 DNA methylation involved in embryo development(GO:0043045) C-5 methylation of cytosine(GO:0090116) changes to DNA methylation involved in embryo development(GO:1901538)
0.5 7.1 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.5 4.3 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.5 4.7 GO:0040016 embryonic cleavage(GO:0040016)
0.5 5.6 GO:0007097 nuclear migration(GO:0007097)
0.5 2.8 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.5 6.0 GO:0006265 DNA topological change(GO:0006265)
0.5 5.5 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.5 5.0 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.5 2.3 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.5 2.3 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.4 0.9 GO:0060525 prostate glandular acinus development(GO:0060525) prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.4 2.2 GO:0070417 cellular response to cold(GO:0070417)
0.4 6.6 GO:0002021 response to dietary excess(GO:0002021)
0.4 1.3 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.4 2.2 GO:0045471 response to ethanol(GO:0045471)
0.4 4.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.4 2.1 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.4 1.7 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.4 2.1 GO:1904764 clathrin coat disassembly(GO:0072318) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.4 1.3 GO:1904247 regulation of polynucleotide adenylyltransferase activity(GO:1904245) positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.4 3.4 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.4 1.3 GO:0006788 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806)
0.4 1.7 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.4 1.2 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.4 3.7 GO:0008343 adult feeding behavior(GO:0008343)
0.4 0.4 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.4 1.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.4 2.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.4 2.0 GO:2000769 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
0.4 1.6 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.4 30.8 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.4 3.1 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.4 2.3 GO:0044351 macropinocytosis(GO:0044351)
0.4 5.4 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.4 4.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.4 1.9 GO:0051941 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.4 1.9 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.4 1.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.4 25.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.4 3.0 GO:1904417 regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.4 2.6 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.4 10.6 GO:0070987 error-free translesion synthesis(GO:0070987)
0.4 4.6 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.4 1.1 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.3 2.1 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.3 2.4 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.3 2.4 GO:0050893 sensory processing(GO:0050893)
0.3 15.1 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.3 1.0 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.3 12.0 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.3 1.0 GO:0046066 dGDP metabolic process(GO:0046066)
0.3 1.0 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.3 1.6 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.3 4.0 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.3 3.4 GO:0009414 response to water deprivation(GO:0009414)
0.3 1.8 GO:1902570 protein localization to nucleolus(GO:1902570)
0.3 17.7 GO:1990090 cellular response to nerve growth factor stimulus(GO:1990090)
0.3 0.9 GO:0019474 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.3 3.6 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.3 3.9 GO:2000394 phosphatidylcholine catabolic process(GO:0034638) positive regulation of lamellipodium morphogenesis(GO:2000394)
0.3 2.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.3 1.5 GO:0072553 terminal button organization(GO:0072553)
0.3 1.7 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.3 1.4 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.3 0.9 GO:0001555 oocyte growth(GO:0001555) regulation of progesterone secretion(GO:2000870)
0.3 9.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.3 4.8 GO:0043302 positive regulation of leukocyte degranulation(GO:0043302)
0.3 1.1 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.3 3.9 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.3 8.7 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.3 3.5 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.3 1.1 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.3 8.0 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.3 2.6 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.3 2.6 GO:0015701 bicarbonate transport(GO:0015701)
0.3 0.3 GO:0019046 release from viral latency(GO:0019046)
0.2 3.0 GO:0021924 cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.2 0.7 GO:0021571 rhombomere 5 development(GO:0021571)
0.2 0.2 GO:0044861 protein localization to plasma membrane raft(GO:0044860) protein transport into plasma membrane raft(GO:0044861)
0.2 2.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 4.2 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858)
0.2 2.4 GO:0042908 xenobiotic transport(GO:0042908)
0.2 18.1 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.2 14.7 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.2 0.5 GO:0034127 regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034127) negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.2 5.0 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.2 13.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.2 1.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.2 5.3 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.2 1.6 GO:0061635 regulation of protein complex stability(GO:0061635)
0.2 1.8 GO:0006907 pinocytosis(GO:0006907)
0.2 2.5 GO:0048484 enteric nervous system development(GO:0048484)
0.2 0.5 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.2 0.4 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.2 0.7 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.2 1.5 GO:0044266 angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.2 3.5 GO:0035855 megakaryocyte development(GO:0035855)
0.2 1.1 GO:0000075 cell cycle checkpoint(GO:0000075)
0.2 1.7 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.2 1.9 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.2 2.1 GO:0002634 regulation of germinal center formation(GO:0002634)
0.2 1.2 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.2 6.4 GO:0071173 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.2 19.4 GO:0030183 B cell differentiation(GO:0030183)
0.2 0.4 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.2 1.4 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.2 1.6 GO:0015074 DNA integration(GO:0015074)
0.2 1.2 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.2 7.4 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.2 7.0 GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
0.2 4.0 GO:0016180 snRNA processing(GO:0016180)
0.2 4.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.2 0.6 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.2 1.9 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.2 1.9 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.2 4.9 GO:0090659 adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.2 2.6 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.2 2.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 1.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.2 1.5 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069) positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.2 13.0 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.2 1.8 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.2 2.9 GO:0000338 protein deneddylation(GO:0000338)
0.2 2.3 GO:1903432 regulation of TORC1 signaling(GO:1903432)
0.2 2.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.2 2.5 GO:2001234 negative regulation of apoptotic signaling pathway(GO:2001234)
0.2 10.9 GO:0055072 iron ion homeostasis(GO:0055072)
0.2 0.2 GO:0016078 tRNA catabolic process(GO:0016078)
0.2 0.2 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.2 0.9 GO:0001771 immunological synapse formation(GO:0001771)
0.2 0.7 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.2 1.6 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.2 1.4 GO:0010737 protein kinase A signaling(GO:0010737) regulation of protein kinase A signaling(GO:0010738)
0.2 1.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 3.7 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.2 2.0 GO:0035372 protein localization to microtubule(GO:0035372)
0.2 9.2 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.2 2.1 GO:0046007 negative regulation of meiotic nuclear division(GO:0045835) negative regulation of activated T cell proliferation(GO:0046007)
0.2 3.1 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.2 1.5 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.2 1.1 GO:0099612 protein localization to axon(GO:0099612)
0.2 3.5 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.2 1.9 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 0.9 GO:0070255 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.2 11.1 GO:0048678 response to axon injury(GO:0048678)
0.2 2.6 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.2 5.4 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.2 5.7 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.9 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 1.3 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 1.5 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 3.2 GO:0006397 mRNA processing(GO:0006397)
0.1 2.5 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.1 5.8 GO:0043303 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.1 10.3 GO:0035308 negative regulation of protein dephosphorylation(GO:0035308)
0.1 5.1 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 2.3 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1 1.0 GO:0005984 disaccharide metabolic process(GO:0005984)
0.1 0.9 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.1 0.9 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384) tRNA transcription(GO:0009304) 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 1.7 GO:0014029 neural crest formation(GO:0014029)
0.1 0.4 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 1.4 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 1.8 GO:0003094 glomerular filtration(GO:0003094)
0.1 2.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.3 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.1 0.3 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 1.5 GO:0016446 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 5.6 GO:0014047 glutamate secretion(GO:0014047)
0.1 4.6 GO:0045776 negative regulation of blood pressure(GO:0045776)
0.1 1.5 GO:0035878 nail development(GO:0035878)
0.1 2.7 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 1.1 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 2.4 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 1.6 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 1.0 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.1 1.6 GO:0097178 ruffle assembly(GO:0097178)
0.1 0.6 GO:0098810 neurotransmitter reuptake(GO:0098810)
0.1 0.8 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 1.6 GO:1900116 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 2.6 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.5 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 0.4 GO:0035376 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.1 0.8 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 1.9 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 3.5 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1 3.0 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 1.4 GO:0030282 bone mineralization(GO:0030282)
0.1 2.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 1.0 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 3.3 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 2.9 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 7.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 2.4 GO:0008089 anterograde axonal transport(GO:0008089)
0.1 0.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 3.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 1.9 GO:0001525 angiogenesis(GO:0001525)
0.1 3.2 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.1 0.7 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.1 1.0 GO:0031167 rRNA methylation(GO:0031167)
0.1 11.2 GO:0008643 carbohydrate transport(GO:0008643)
0.1 0.7 GO:0015846 polyamine transport(GO:0015846)
0.1 0.5 GO:0050915 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) sensory perception of sour taste(GO:0050915)
0.1 0.4 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.1 1.7 GO:0006465 signal peptide processing(GO:0006465)
0.1 1.2 GO:0042755 eating behavior(GO:0042755)
0.1 1.3 GO:0009650 UV protection(GO:0009650)
0.1 1.0 GO:0006681 galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374)
0.1 2.0 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 1.4 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.1 2.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 5.8 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.1 2.8 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 0.4 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.1 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 3.0 GO:0030818 negative regulation of cAMP biosynthetic process(GO:0030818)
0.1 0.9 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 4.0 GO:0006811 ion transport(GO:0006811)
0.1 1.0 GO:0009303 rRNA transcription(GO:0009303)
0.1 2.6 GO:0006929 substrate-dependent cell migration(GO:0006929)
0.1 1.0 GO:0006109 regulation of carbohydrate metabolic process(GO:0006109)
0.1 0.5 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1 4.1 GO:0007602 phototransduction(GO:0007602)
0.1 2.5 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 1.0 GO:0072348 sulfur compound transport(GO:0072348)
0.1 0.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.2 GO:0021637 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 1.0 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.2 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.1 0.1 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 0.2 GO:0032438 melanosome organization(GO:0032438) pigment granule organization(GO:0048753)
0.1 1.4 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.1 0.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 1.3 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.1 0.4 GO:0010818 T cell chemotaxis(GO:0010818)
0.1 0.4 GO:0035865 cellular response to potassium ion(GO:0035865)
0.1 0.5 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 0.3 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.1 0.4 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.7 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 1.5 GO:0007098 centrosome cycle(GO:0007098) centrosome organization(GO:0051297)
0.1 0.2 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 1.4 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 4.3 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 1.0 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.8 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.3 GO:0051923 sulfation(GO:0051923)
0.0 1.9 GO:0044070 regulation of anion transport(GO:0044070)
0.0 0.7 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.9 GO:0018126 protein hydroxylation(GO:0018126)
0.0 2.1 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.3 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 1.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.6 GO:0006875 cellular metal ion homeostasis(GO:0006875)
0.0 0.2 GO:0019086 late viral transcription(GO:0019086)
0.0 0.3 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 0.6 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 2.6 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.5 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.1 GO:0070105 regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 10.4 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.5 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.1 GO:0002763 positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.0 1.1 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.2 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.5 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.7 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 0.5 GO:0048265 response to pain(GO:0048265)
0.0 0.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 1.8 GO:0003279 cardiac septum development(GO:0003279)
0.0 1.8 GO:0006968 cellular defense response(GO:0006968)
0.0 0.7 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 2.3 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 1.6 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.2 GO:0007379 segment specification(GO:0007379)
0.0 0.4 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.8 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.3 GO:0001755 neural crest cell migration(GO:0001755)
0.0 0.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 11.8 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.2 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0097056 seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0 1.2 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.2 GO:0048546 digestive tract morphogenesis(GO:0048546)
0.0 0.3 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.3 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.9 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.1 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 0.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.2 GO:0051784 negative regulation of nuclear division(GO:0051784)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
7.5 59.7 GO:0097208 alveolar lamellar body(GO:0097208)
5.5 38.4 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
5.4 16.1 GO:0019034 viral replication complex(GO:0019034)
5.3 26.7 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
4.6 18.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
3.5 14.0 GO:0033596 TSC1-TSC2 complex(GO:0033596)
3.5 24.5 GO:0030121 AP-1 adaptor complex(GO:0030121)
3.4 17.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
3.3 13.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
3.1 18.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
3.0 42.5 GO:0030897 HOPS complex(GO:0030897)
3.0 12.1 GO:0033263 CORVET complex(GO:0033263)
2.9 17.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
2.7 21.4 GO:0000322 storage vacuole(GO:0000322)
1.9 14.9 GO:1990111 spermatoproteasome complex(GO:1990111)
1.8 16.5 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
1.8 7.3 GO:1990246 uniplex complex(GO:1990246)
1.7 10.5 GO:0000138 Golgi trans cisterna(GO:0000138)
1.5 26.5 GO:0031083 BLOC-1 complex(GO:0031083)
1.4 13.9 GO:0097413 Lewy body(GO:0097413)
1.3 7.7 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
1.3 34.7 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
1.2 15.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
1.2 8.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
1.1 4.3 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
1.0 28.0 GO:0034362 low-density lipoprotein particle(GO:0034362)
1.0 52.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
1.0 30.6 GO:0035371 microtubule plus-end(GO:0035371)
0.9 3.8 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.9 2.7 GO:0005879 axonemal microtubule(GO:0005879)
0.9 8.2 GO:0005827 polar microtubule(GO:0005827)
0.9 19.6 GO:0071004 U2-type prespliceosome(GO:0071004)
0.8 3.3 GO:0055087 Ski complex(GO:0055087)
0.8 1.6 GO:1903349 omegasome membrane(GO:1903349)
0.8 3.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.8 5.6 GO:1990635 proximal dendrite(GO:1990635)
0.8 4.8 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.8 11.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.8 3.8 GO:0044530 supraspliceosomal complex(GO:0044530)
0.8 20.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.8 10.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.7 8.8 GO:0030008 TRAPP complex(GO:0030008)
0.7 3.6 GO:0033553 rDNA heterochromatin(GO:0033553)
0.7 7.9 GO:0005869 dynactin complex(GO:0005869)
0.7 14.9 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.7 5.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.6 20.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.6 2.4 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.6 7.2 GO:1990909 catenin complex(GO:0016342) Wnt signalosome(GO:1990909)
0.6 5.3 GO:0005955 calcineurin complex(GO:0005955)
0.6 2.9 GO:0030870 Mre11 complex(GO:0030870)
0.6 11.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.6 7.0 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.6 6.9 GO:0033093 Weibel-Palade body(GO:0033093)
0.6 3.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.6 2.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.6 1.7 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.6 3.9 GO:0036021 endolysosome lumen(GO:0036021)
0.6 10.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.5 4.4 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.5 1.6 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.5 1.6 GO:0000346 transcription export complex(GO:0000346)
0.5 8.0 GO:0042405 nuclear inclusion body(GO:0042405)
0.5 4.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.5 4.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.5 8.6 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.5 5.9 GO:0060077 inhibitory synapse(GO:0060077)
0.5 21.7 GO:0043198 dendritic shaft(GO:0043198)
0.5 11.2 GO:0071141 SMAD protein complex(GO:0071141)
0.5 1.9 GO:0005638 lamin filament(GO:0005638)
0.5 44.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.5 168.4 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.5 4.7 GO:0035253 ciliary rootlet(GO:0035253)
0.5 4.6 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.5 17.0 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.4 38.7 GO:0070821 tertiary granule membrane(GO:0070821)
0.4 3.9 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.4 4.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.4 4.3 GO:0042587 glycogen granule(GO:0042587)
0.4 2.9 GO:0001741 XY body(GO:0001741)
0.4 10.2 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.4 5.6 GO:0005875 microtubule associated complex(GO:0005875)
0.4 10.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.4 1.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.4 2.3 GO:0071817 MMXD complex(GO:0071817)
0.4 1.8 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.4 5.1 GO:0005883 neurofilament(GO:0005883)
0.4 1.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.4 1.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.4 1.1 GO:0044609 DBIRD complex(GO:0044609)
0.4 1.1 GO:0034657 GID complex(GO:0034657)
0.3 44.4 GO:0016605 PML body(GO:0016605)
0.3 4.1 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.3 0.7 GO:0030120 vesicle coat(GO:0030120)
0.3 1.0 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.3 5.0 GO:0048786 presynaptic active zone(GO:0048786)
0.3 2.5 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.3 1.9 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
0.3 5.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.3 52.8 GO:0005802 trans-Golgi network(GO:0005802)
0.3 3.9 GO:0097470 ribbon synapse(GO:0097470)
0.3 34.3 GO:0005604 basement membrane(GO:0005604)
0.3 4.1 GO:0035861 site of double-strand break(GO:0035861)
0.3 4.0 GO:0098797 plasma membrane protein complex(GO:0098797)
0.3 5.4 GO:0000242 pericentriolar material(GO:0000242)
0.3 2.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 110.7 GO:0016607 nuclear speck(GO:0016607)
0.3 10.0 GO:0008180 COP9 signalosome(GO:0008180)
0.3 0.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.2 27.2 GO:0043202 lysosomal lumen(GO:0043202)
0.2 17.8 GO:0042734 presynaptic membrane(GO:0042734)
0.2 1.7 GO:0005787 signal peptidase complex(GO:0005787)
0.2 4.1 GO:0032059 bleb(GO:0032059)
0.2 1.9 GO:0032039 integrator complex(GO:0032039)
0.2 4.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 6.5 GO:0044306 neuron projection terminus(GO:0044306)
0.2 10.1 GO:0030133 transport vesicle(GO:0030133)
0.2 1.5 GO:0032389 MutLalpha complex(GO:0032389)
0.2 1.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.2 2.3 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.2 3.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 26.3 GO:0005770 late endosome(GO:0005770)
0.2 1.4 GO:0030914 STAGA complex(GO:0030914)
0.2 2.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 1.0 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 1.1 GO:1990769 proximal neuron projection(GO:1990769)
0.2 2.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 1.1 GO:0005927 muscle tendon junction(GO:0005927)
0.2 0.9 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.2 0.5 GO:0097447 dendritic tree(GO:0097447)
0.2 0.5 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.2 8.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 2.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.2 3.9 GO:0042101 T cell receptor complex(GO:0042101)
0.2 4.4 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.2 2.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.2 16.2 GO:0030175 filopodium(GO:0030175)
0.2 8.8 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 3.0 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.1 0.7 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 3.0 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 14.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 1.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.9 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 4.2 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 0.7 GO:0070847 core mediator complex(GO:0070847)
0.1 6.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.6 GO:0097452 GAIT complex(GO:0097452)
0.1 11.4 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 2.7 GO:1904115 axon cytoplasm(GO:1904115)
0.1 1.8 GO:0043235 receptor complex(GO:0043235)
0.1 88.2 GO:0045202 synapse(GO:0045202)
0.1 13.6 GO:0000922 spindle pole(GO:0000922)
0.1 2.0 GO:0097342 ripoptosome(GO:0097342)
0.1 0.6 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 16.1 GO:0030424 axon(GO:0030424)
0.1 6.8 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 0.6 GO:0005915 zonula adherens(GO:0005915)
0.1 3.5 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)
0.1 0.6 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 1.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 1.5 GO:0031430 M band(GO:0031430)
0.1 3.3 GO:1990391 DNA repair complex(GO:1990391)
0.1 1.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 1.0 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 4.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 0.4 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 3.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 8.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 0.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 1.6 GO:0000792 heterochromatin(GO:0000792)
0.1 0.6 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1 3.1 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 0.7 GO:0016528 sarcoplasm(GO:0016528)
0.0 3.2 GO:0030027 lamellipodium(GO:0030027)
0.0 1.8 GO:0035579 specific granule membrane(GO:0035579)
0.0 9.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.3 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 11.7 GO:0005768 endosome(GO:0005768)
0.0 4.7 GO:0043025 neuronal cell body(GO:0043025)
0.0 2.4 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 3.7 GO:0005874 microtubule(GO:0005874)
0.0 0.8 GO:0031526 brush border membrane(GO:0031526)
0.0 0.5 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0030426 growth cone(GO:0030426)
0.0 0.8 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.0 2.4 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.6 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 2.5 GO:0072562 blood microparticle(GO:0072562)
0.0 1.5 GO:0045111 intermediate filament cytoskeleton(GO:0045111)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.3 36.5 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
6.7 20.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
6.6 19.8 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
6.2 24.9 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
4.4 35.0 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
4.3 47.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
4.2 25.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
4.0 11.9 GO:0008859 exoribonuclease II activity(GO:0008859)
3.9 85.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
3.4 10.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
3.3 13.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
3.3 9.9 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
3.3 9.8 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
3.2 22.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
3.1 18.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
3.1 12.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
3.1 12.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
2.9 8.6 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
2.6 26.0 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
2.6 10.3 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
2.6 15.4 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
2.1 23.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
2.1 44.9 GO:0015929 hexosaminidase activity(GO:0015929)
2.1 60.2 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442)
2.0 9.8 GO:0034046 poly(G) binding(GO:0034046)
1.9 5.8 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
1.8 28.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
1.7 10.4 GO:0035500 MH2 domain binding(GO:0035500)
1.7 8.3 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
1.7 5.0 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
1.7 5.0 GO:0033149 FFAT motif binding(GO:0033149)
1.5 13.9 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
1.5 13.8 GO:0043426 MRF binding(GO:0043426)
1.5 6.0 GO:0043398 HLH domain binding(GO:0043398)
1.5 29.9 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
1.5 8.8 GO:0003998 acylphosphatase activity(GO:0003998)
1.4 17.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
1.4 8.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
1.4 109.8 GO:0005507 copper ion binding(GO:0005507)
1.4 5.5 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
1.3 5.2 GO:0034057 RNA strand-exchange activity(GO:0034057)
1.3 3.8 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
1.2 21.1 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
1.2 2.4 GO:0008384 IkappaB kinase activity(GO:0008384)
1.2 53.2 GO:0050699 WW domain binding(GO:0050699)
1.2 4.6 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
1.1 3.3 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
1.1 3.2 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
1.1 8.5 GO:0035374 chondroitin sulfate binding(GO:0035374)
1.1 2.1 GO:0070087 chromo shadow domain binding(GO:0070087)
1.0 4.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
1.0 6.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
1.0 5.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
1.0 3.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
1.0 6.0 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
1.0 3.8 GO:0032406 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
1.0 3.8 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
1.0 4.8 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.9 2.8 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.9 2.8 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.9 3.8 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.9 5.6 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.9 4.7 GO:0070097 delta-catenin binding(GO:0070097)
0.9 0.9 GO:0001031 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) 5S rDNA binding(GO:0080084)
0.9 13.9 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.9 17.4 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.9 3.7 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.9 3.6 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.9 6.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.9 5.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.9 5.1 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.8 21.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.8 1.6 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.8 3.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.7 4.3 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.7 11.5 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.7 4.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.7 4.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.7 2.8 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.7 8.9 GO:0008199 ferric iron binding(GO:0008199)
0.7 68.4 GO:0001618 virus receptor activity(GO:0001618)
0.7 24.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.7 3.3 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.7 0.7 GO:0070538 oleic acid binding(GO:0070538)
0.7 2.0 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.6 19.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.6 4.5 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.6 6.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.6 1.3 GO:0004630 phospholipase D activity(GO:0004630)
0.6 17.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.6 11.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.6 6.7 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.6 3.0 GO:0070404 NADH binding(GO:0070404)
0.6 2.3 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.6 2.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.6 1.7 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.6 5.0 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.6 2.8 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.6 11.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.5 3.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.5 4.9 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.5 2.7 GO:0033592 RNA strand annealing activity(GO:0033592)
0.5 5.9 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.5 5.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.5 14.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.5 3.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.5 2.6 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.5 27.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.5 4.5 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.5 5.6 GO:0070569 uridylyltransferase activity(GO:0070569)
0.5 11.6 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.5 5.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.5 3.0 GO:0008142 oxysterol binding(GO:0008142)
0.5 2.9 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.5 1.8 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.5 4.5 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.5 11.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.4 4.5 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.4 2.6 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.4 4.3 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.4 8.8 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.4 7.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.4 2.0 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.4 2.4 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.4 3.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.4 2.0 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.4 3.9 GO:0030957 Tat protein binding(GO:0030957)
0.4 30.6 GO:0019905 syntaxin binding(GO:0019905)
0.4 2.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.4 11.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.4 3.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.4 5.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.4 6.9 GO:0005522 profilin binding(GO:0005522)
0.4 13.6 GO:0005109 frizzled binding(GO:0005109)
0.4 1.9 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.4 3.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.4 9.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.4 5.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.4 4.7 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.4 2.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.3 1.0 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.3 18.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.3 20.6 GO:0030276 clathrin binding(GO:0030276)
0.3 3.7 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.3 4.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 5.7 GO:0045295 gamma-catenin binding(GO:0045295)
0.3 8.3 GO:0005521 lamin binding(GO:0005521)
0.3 1.0 GO:0051185 coenzyme transporter activity(GO:0051185)
0.3 3.6 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.3 1.6 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.3 1.0 GO:1904288 BAT3 complex binding(GO:1904288)
0.3 1.9 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.3 1.2 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.3 2.4 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.3 6.9 GO:0031489 myosin V binding(GO:0031489)
0.3 10.6 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.3 8.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.3 1.5 GO:0000182 rDNA binding(GO:0000182)
0.3 3.2 GO:0030274 LIM domain binding(GO:0030274)
0.3 1.4 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.3 1.4 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.3 1.6 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.3 3.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 1.6 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.3 1.8 GO:0034452 dynactin binding(GO:0034452)
0.3 5.2 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.3 1.3 GO:0070878 primary miRNA binding(GO:0070878)
0.3 4.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.3 2.8 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.2 22.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.2 15.9 GO:0019003 GDP binding(GO:0019003)
0.2 4.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 1.9 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 5.6 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.2 63.6 GO:0008017 microtubule binding(GO:0008017)
0.2 0.7 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.2 3.0 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 2.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 6.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 0.9 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 1.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2 2.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 0.4 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.2 1.5 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.2 3.0 GO:0008097 5S rRNA binding(GO:0008097)
0.2 4.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 3.7 GO:0017081 chloride channel regulator activity(GO:0017081)
0.2 3.4 GO:0004697 protein kinase C activity(GO:0004697)
0.2 6.3 GO:0000149 SNARE binding(GO:0000149)
0.2 4.3 GO:0001968 fibronectin binding(GO:0001968)
0.2 8.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.2 2.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 1.0 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 4.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 2.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.2 2.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 17.0 GO:0051117 ATPase binding(GO:0051117)
0.2 12.5 GO:0050661 NADP binding(GO:0050661)
0.2 2.0 GO:0051434 BH3 domain binding(GO:0051434)
0.2 1.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.2 0.5 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.2 5.6 GO:0015026 coreceptor activity(GO:0015026)
0.2 6.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 2.2 GO:0031005 filamin binding(GO:0031005)
0.2 1.0 GO:0008430 thyroxine 5'-deiodinase activity(GO:0004800) selenium binding(GO:0008430)
0.2 11.6 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.2 10.1 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.2 0.7 GO:0017018 myosin phosphatase activity(GO:0017018)
0.2 14.1 GO:0008565 protein transporter activity(GO:0008565)
0.2 0.7 GO:0036033 mediator complex binding(GO:0036033)
0.2 1.8 GO:0097016 L27 domain binding(GO:0097016)
0.2 1.1 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.2 7.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.2 66.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.2 2.0 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.2 3.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.2 2.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 1.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 2.0 GO:0098847 sequence-specific single stranded DNA binding(GO:0098847)
0.1 4.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 9.0 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.1 2.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 15.1 GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups(GO:0016747)
0.1 0.4 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.4 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.1 2.2 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1 5.7 GO:0043022 ribosome binding(GO:0043022)
0.1 3.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 3.5 GO:0019894 kinesin binding(GO:0019894)
0.1 1.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 3.0 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 2.8 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.1 22.8 GO:0051015 actin filament binding(GO:0051015)
0.1 1.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 2.8 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 4.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 2.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 10.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 9.9 GO:0047485 protein N-terminus binding(GO:0047485)
0.1 32.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 2.2 GO:0015149 hexose transmembrane transporter activity(GO:0015149)
0.1 0.8 GO:0019534 toxin transporter activity(GO:0019534)
0.1 1.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.0 GO:0031386 protein tag(GO:0031386)
0.1 1.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 5.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 3.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.5 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 2.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 1.7 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 0.6 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.5 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 1.5 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 1.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.3 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 1.2 GO:0042923 neuropeptide binding(GO:0042923)
0.1 9.8 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.1 1.4 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.4 GO:0008312 7S RNA binding(GO:0008312)
0.1 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.7 GO:0070888 E-box binding(GO:0070888)
0.1 2.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 1.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.6 GO:0036122 BMP binding(GO:0036122)
0.1 6.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 0.7 GO:0035240 dopamine binding(GO:0035240)
0.1 6.2 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.6 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.1 1.6 GO:0004016 adenylate cyclase activity(GO:0004016) guanylate cyclase activity(GO:0004383)
0.1 5.8 GO:0044325 ion channel binding(GO:0044325)
0.1 0.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.6 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 0.9 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 0.4 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 12.4 GO:0005096 GTPase activator activity(GO:0005096)
0.1 1.6 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.1 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 1.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.9 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 7.2 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.3 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.4 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.0 0.9 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.4 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 1.3 GO:0051213 dioxygenase activity(GO:0051213)
0.0 0.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 2.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 4.7 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.2 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 2.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.8 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 0.4 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.4 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 2.6 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 12.0 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.8 24.6 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.6 8.6 PID IL5 PATHWAY IL5-mediated signaling events
0.6 7.7 ST STAT3 PATHWAY STAT3 Pathway
0.6 29.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.6 20.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.6 22.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.6 30.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.5 41.0 PID LKB1 PATHWAY LKB1 signaling events
0.5 10.7 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.5 25.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.5 38.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.4 10.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.4 10.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.4 14.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.4 11.2 ST GAQ PATHWAY G alpha q Pathway
0.3 8.1 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.3 6.5 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.3 13.8 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.3 7.3 PID EPO PATHWAY EPO signaling pathway
0.3 18.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.3 4.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.2 5.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 9.5 PID ATM PATHWAY ATM pathway
0.2 9.5 PID ARF6 PATHWAY Arf6 signaling events
0.2 0.4 ST JAK STAT PATHWAY Jak-STAT Pathway
0.2 19.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.2 6.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.2 2.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.2 4.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.2 7.3 PID RHOA PATHWAY RhoA signaling pathway
0.2 6.8 PID MYC PATHWAY C-MYC pathway
0.2 8.6 PID CDC42 PATHWAY CDC42 signaling events
0.2 6.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 6.7 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.2 2.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 5.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.2 5.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 0.4 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 32.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 2.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 2.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 1.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 6.5 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.1 1.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 7.1 PID CMYB PATHWAY C-MYB transcription factor network
0.1 2.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 3.3 PID TNF PATHWAY TNF receptor signaling pathway
0.1 1.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 5.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 2.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 2.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 3.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 1.4 PID IL1 PATHWAY IL1-mediated signaling events
0.1 1.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 2.1 PID AURORA A PATHWAY Aurora A signaling
0.1 0.8 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 2.3 PID FGF PATHWAY FGF signaling pathway
0.1 1.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 1.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 5.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.2 PID FAS PATHWAY FAS (CD95) signaling pathway
0.1 1.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 2.6 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 2.6 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.6 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.6 PID INSULIN PATHWAY Insulin Pathway
0.0 0.9 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 3.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 3.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 23.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
2.0 64.2 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
1.6 28.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
1.5 27.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
1.0 14.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
1.0 40.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
1.0 3.9 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.8 9.7 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.8 20.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.8 20.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.8 14.6 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.7 7.8 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.7 14.2 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.7 15.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.7 4.0 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.7 7.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.6 5.8 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.6 24.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.6 16.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.6 1.7 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.6 12.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.5 28.3 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.5 95.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.5 8.7 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.5 9.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.5 9.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.5 3.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.4 16.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.4 36.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.4 4.6 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.4 4.6 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.4 20.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.4 18.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.4 12.8 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.4 6.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.4 6.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.3 7.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.3 7.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.3 5.0 REACTOME MEIOSIS Genes involved in Meiosis
0.3 5.9 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.3 17.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.3 3.7 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.3 1.5 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.2 13.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.2 4.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 6.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 5.8 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 3.7 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.2 5.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 49.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.2 2.0 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.2 9.5 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.2 1.7 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.2 4.5 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.2 5.0 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.2 3.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 1.7 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.2 0.9 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2 3.8 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.2 6.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.2 5.3 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.2 15.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.2 2.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 6.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 8.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.2 3.0 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.2 3.8 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.2 6.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 10.6 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.2 2.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 6.9 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 2.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 2.3 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 8.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 3.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 10.2 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.1 6.7 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 3.0 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 12.6 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 6.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.3 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 2.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 1.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 2.0 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 2.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 2.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 0.7 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 2.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.1 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.1 1.6 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 3.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 2.8 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 0.9 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 0.3 REACTOME G PROTEIN BETA GAMMA SIGNALLING Genes involved in G-protein beta:gamma signalling
0.1 2.9 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.1 1.1 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 0.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 1.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 3.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 2.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 3.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.0 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.5 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.4 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.5 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 1.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.2 REACTOME TRANSLATION Genes involved in Translation
0.0 1.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production