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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for NHLH1

Z-value: 0.71

Motif logo

Transcription factors associated with NHLH1

Gene Symbol Gene ID Gene Info
ENSG00000171786.5 nescient helix-loop-helix 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NHLH1hg19_v2_chr1_+_160336851_1603368680.243.6e-04Click!

Activity profile of NHLH1 motif

Sorted Z-values of NHLH1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_23847267 64.41 ENST00000321728.7
protein kinase C, beta
chr16_+_23847339 47.08 ENST00000303531.7
protein kinase C, beta
chr14_+_90863327 29.62 ENST00000356978.4
calmodulin 1 (phosphorylase kinase, delta)
chr10_+_105036909 27.30 ENST00000369849.4
internexin neuronal intermediate filament protein, alpha
chr8_+_24771265 24.93 ENST00000518131.1
ENST00000437366.2
neurofilament, medium polypeptide
chr8_+_24772455 22.87 ENST00000433454.2
neurofilament, medium polypeptide
chr14_+_100150622 22.61 ENST00000261835.3
cytochrome P450, family 46, subfamily A, polypeptide 1
chr19_+_35521572 19.10 ENST00000262631.5
sodium channel, voltage-gated, type I, beta subunit
chr20_+_44036900 18.76 ENST00000443296.1
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr20_+_44036620 17.98 ENST00000372710.3
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr1_-_21948906 17.56 ENST00000374761.2
ENST00000599760.1
RAP1 GTPase activating protein
chr14_+_90863364 17.48 ENST00000447653.3
ENST00000553542.1
calmodulin 1 (phosphorylase kinase, delta)
chr9_-_111929560 17.28 ENST00000561981.2
ferric-chelate reductase 1-like
chr13_-_36705425 17.02 ENST00000255448.4
ENST00000360631.3
ENST00000379892.4
doublecortin-like kinase 1
chr1_-_182360918 16.63 ENST00000339526.4
glutamate-ammonia ligase
chr6_-_84418841 16.57 ENST00000369694.2
ENST00000195649.6
synaptosomal-associated protein, 91kDa
chr6_-_84418860 16.54 ENST00000521743.1
synaptosomal-associated protein, 91kDa
chr1_+_51701924 16.50 ENST00000242719.3
ring finger protein 11
chr6_-_84419101 16.23 ENST00000520302.1
ENST00000520213.1
ENST00000439399.2
ENST00000428679.2
ENST00000437520.1
synaptosomal-associated protein, 91kDa
chr20_+_37434329 15.87 ENST00000299824.1
ENST00000373331.2
protein phosphatase 1, regulatory subunit 16B
chr3_-_133614421 15.59 ENST00000543906.1
RAB6B, member RAS oncogene family
chr22_+_32340481 15.53 ENST00000397492.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr22_+_32340447 15.50 ENST00000248975.5
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr7_-_766879 15.20 ENST00000537384.1
ENST00000417852.1
protein kinase, cAMP-dependent, regulatory, type I, beta
chr16_+_6533380 15.19 ENST00000552089.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr19_+_35521616 15.03 ENST00000595652.1
sodium channel, voltage-gated, type I, beta subunit
chr17_-_56606664 15.00 ENST00000580844.1
septin 4
chr17_-_56606705 14.95 ENST00000317268.3
septin 4
chr17_-_56606639 14.86 ENST00000579371.1
septin 4
chr4_-_102268484 14.78 ENST00000394853.4
protein phosphatase 3, catalytic subunit, alpha isozyme
chr1_-_3713042 14.49 ENST00000378251.1
leucine rich repeat containing 47
chr1_-_85930823 14.39 ENST00000284031.8
ENST00000539042.1
dimethylarginine dimethylaminohydrolase 1
chr4_-_102268628 14.13 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
protein phosphatase 3, catalytic subunit, alpha isozyme
chr16_+_330581 13.95 ENST00000219409.3
Rho GDP dissociation inhibitor (GDI) gamma
chr1_-_182360498 13.56 ENST00000417584.2
glutamate-ammonia ligase
chr8_-_98290087 13.41 ENST00000322128.3
TSPY-like 5
chr11_+_17756279 13.13 ENST00000265969.6
potassium voltage-gated channel, Shaw-related subfamily, member 1
chr1_+_33352036 13.02 ENST00000373467.3
hippocalcin
chr3_+_167453493 12.96 ENST00000295777.5
ENST00000472747.2
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr3_-_133614597 12.93 ENST00000285208.4
ENST00000460865.3
RAB6B, member RAS oncogene family
chr5_+_156693091 12.70 ENST00000318218.6
ENST00000442283.2
ENST00000522463.1
ENST00000521420.1
cytoplasmic FMR1 interacting protein 2
chr5_+_156693159 12.48 ENST00000347377.6
cytoplasmic FMR1 interacting protein 2
chr18_-_5544241 12.39 ENST00000341928.2
ENST00000540638.2
erythrocyte membrane protein band 4.1-like 3
chr19_+_47104493 12.14 ENST00000291295.9
ENST00000597743.1
calmodulin 3 (phosphorylase kinase, delta)
chr11_-_66336060 12.03 ENST00000310325.5
cathepsin F
chr12_-_6580094 11.85 ENST00000361716.3
vesicle-associated membrane protein 1 (synaptobrevin 1)
chrX_+_110187513 11.72 ENST00000446737.1
ENST00000425146.1
p21 protein (Cdc42/Rac)-activated kinase 3
chr15_+_25200074 11.71 ENST00000390687.4
ENST00000584968.1
ENST00000346403.6
ENST00000554227.2
small nuclear ribonucleoprotein polypeptide N
chr13_-_45150392 11.66 ENST00000501704.2
TSC22 domain family, member 1
chr4_+_154074217 11.50 ENST00000437508.2
tripartite motif containing 2
chr17_-_79139817 11.41 ENST00000326724.4
apoptosis-associated tyrosine kinase
chr1_+_50575292 11.37 ENST00000371821.1
ENST00000371819.1
ELAV like neuron-specific RNA binding protein 4
chr19_-_49944806 11.12 ENST00000221485.3
solute carrier family 17 (vesicular glutamate transporter), member 7
chr1_-_182361327 11.11 ENST00000331872.6
ENST00000311223.5
glutamate-ammonia ligase
chr1_-_177134024 11.02 ENST00000367654.3
astrotactin 1
chr15_+_25200108 11.02 ENST00000577949.1
ENST00000338094.6
ENST00000338327.4
ENST00000579070.1
ENST00000577565.1
SNRPN upstream reading frame protein
small nuclear ribonucleoprotein polypeptide N
chr2_-_86564776 10.89 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
receptor accessory protein 1
chr3_-_33700933 10.61 ENST00000480013.1
cytoplasmic linker associated protein 2
chr17_-_27278304 10.58 ENST00000577226.1
PHD finger protein 12
chr16_+_6533729 10.35 ENST00000551752.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr16_+_1756162 10.27 ENST00000250894.4
ENST00000356010.5
mitogen-activated protein kinase 8 interacting protein 3
chr11_-_66725837 10.11 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
pyruvate carboxylase
chr12_-_90102594 10.08 ENST00000428670.3
ATPase, Ca++ transporting, plasma membrane 1
chr13_+_35516390 10.05 ENST00000540320.1
ENST00000400445.3
ENST00000310336.4
neurobeachin
chr6_+_30848557 9.90 ENST00000460944.2
ENST00000324771.8
discoidin domain receptor tyrosine kinase 1
chr5_+_71403061 9.81 ENST00000512974.1
ENST00000296755.7
microtubule-associated protein 1B
chr3_-_47619623 9.77 ENST00000456150.1
chondroitin sulfate proteoglycan 5 (neuroglycan C)
chr11_-_695162 9.64 ENST00000338675.6
DEAF1 transcription factor
chr6_-_167040731 9.42 ENST00000265678.4
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr15_+_43803143 9.34 ENST00000382031.1
microtubule-associated protein 1A
chr1_-_177133818 9.24 ENST00000424564.2
ENST00000361833.2
astrotactin 1
chr4_-_186697044 9.22 ENST00000437304.2
sorbin and SH3 domain containing 2
chr16_-_29910365 9.20 ENST00000346932.5
ENST00000350527.3
ENST00000537485.1
ENST00000568380.1
seizure related 6 homolog (mouse)-like 2
chr1_+_87797351 9.19 ENST00000370542.1
LIM domain only 4
chr14_-_27066960 9.16 ENST00000539517.2
neuro-oncological ventral antigen 1
chr20_+_57430162 9.15 ENST00000450130.1
ENST00000349036.3
ENST00000423897.1
GNAS complex locus
chr6_-_3157760 9.00 ENST00000333628.3
tubulin, beta 2A class IIa
chr8_+_86376081 8.64 ENST00000285379.5
carbonic anhydrase II
chr12_-_6579808 8.63 ENST00000535180.1
ENST00000400911.3
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr22_+_19705928 8.55 ENST00000383045.3
ENST00000438754.2
septin 5
chr6_+_29624862 8.46 ENST00000376894.4
myelin oligodendrocyte glycoprotein
chr2_-_11810284 8.44 ENST00000306928.5
neurotensin receptor 2
chr19_+_47104553 8.20 ENST00000598871.1
ENST00000594523.1
calmodulin 3 (phosphorylase kinase, delta)
chr6_+_29624758 8.14 ENST00000376917.3
ENST00000376902.3
ENST00000533330.2
ENST00000376888.2
myelin oligodendrocyte glycoprotein
chr3_+_35681081 8.00 ENST00000428373.1
cAMP-regulated phosphoprotein, 21kDa
chr6_+_29624898 7.99 ENST00000396704.3
ENST00000483013.1
ENST00000490427.1
ENST00000416766.2
ENST00000376891.4
ENST00000376898.3
ENST00000396701.2
ENST00000494692.1
ENST00000431798.2
myelin oligodendrocyte glycoprotein
chr8_+_41348173 7.69 ENST00000357743.4
golgin A7
chr20_+_20348740 7.50 ENST00000310227.1
insulinoma-associated 1
chr10_-_127511790 7.49 ENST00000368797.4
ENST00000420761.1
uroporphyrinogen III synthase
chr14_-_23772032 7.43 ENST00000452015.4
protein phosphatase 1, regulatory subunit 3E
chr3_+_50712672 7.37 ENST00000266037.9
dedicator of cytokinesis 3
chr13_+_88324870 7.34 ENST00000325089.6
SLIT and NTRK-like family, member 5
chr7_-_767249 7.34 ENST00000403562.1
protein kinase, cAMP-dependent, regulatory, type I, beta
chr2_-_73511559 7.22 ENST00000521871.1
F-box protein 41
chr14_-_65438865 7.14 ENST00000267512.5
RAB15, member RAS oncogene family
chr20_+_34043085 7.07 ENST00000397527.1
ENST00000342580.4
centrosomal protein 250kDa
chr8_+_41348072 7.05 ENST00000405786.2
golgin A7
chr12_+_121088291 7.05 ENST00000351200.2
calcium binding protein 1
chr1_+_174846570 6.97 ENST00000392064.2
RAB GTPase activating protein 1-like
chr11_+_71238313 6.92 ENST00000398536.4
keratin associated protein 5-7
chr14_+_102027688 6.85 ENST00000510508.4
ENST00000359323.3
deiodinase, iodothyronine, type III
chr11_-_35441524 6.77 ENST00000395750.1
ENST00000449068.1
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr19_+_4304632 6.72 ENST00000597590.1
fibronectin type III and SPRY domain containing 1
chr19_+_4304585 6.67 ENST00000221856.6
fibronectin type III and SPRY domain containing 1
chr22_+_40390930 6.58 ENST00000333407.6
family with sequence similarity 83, member F
chr16_+_330448 6.51 ENST00000447871.1
Rho GDP dissociation inhibitor (GDI) gamma
chr9_-_79307096 6.50 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
prune homolog 2 (Drosophila)
chr3_-_194991876 6.33 ENST00000310380.6
xyloside xylosyltransferase 1
chr7_+_45613958 6.19 ENST00000297323.7
adenylate cyclase 1 (brain)
chr7_+_110731062 6.15 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
leucine rich repeat neuronal 3
chr17_-_56595196 6.14 ENST00000579921.1
ENST00000579925.1
ENST00000323456.5
myotubularin related protein 4
chr16_-_74808710 6.14 ENST00000219368.3
ENST00000544337.1
fatty acid 2-hydroxylase
chrX_-_68385354 6.07 ENST00000361478.1
praja ring finger 1, E3 ubiquitin protein ligase
chr19_+_10217364 5.99 ENST00000430370.1
peter pan homolog (Drosophila)
chr2_+_17935383 5.87 ENST00000524465.1
ENST00000381254.2
ENST00000532257.1
GEN1 Holliday junction 5' flap endonuclease
chr10_-_81205373 5.86 ENST00000372336.3
zinc finger, CCHC domain containing 24
chrX_-_68385274 5.85 ENST00000374584.3
ENST00000590146.1
praja ring finger 1, E3 ubiquitin protein ligase
chr5_+_139493665 5.74 ENST00000331327.3
purine-rich element binding protein A
chr16_+_22825475 5.72 ENST00000261374.3
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr1_+_233749739 5.68 ENST00000366621.3
potassium channel, subfamily K, member 1
chr6_-_146056341 5.63 ENST00000435470.1
epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
chr10_-_103347883 5.56 ENST00000339310.3
ENST00000370158.3
ENST00000299206.4
ENST00000456836.2
ENST00000413344.1
ENST00000429502.1
ENST00000430045.1
ENST00000370172.1
ENST00000436284.2
ENST00000370162.3
polymerase (DNA directed), lambda
chr11_+_125774258 5.50 ENST00000263576.6
DEAD (Asp-Glu-Ala-Asp) box helicase 25
chr14_-_65439132 5.49 ENST00000533601.2
RAB15, member RAS oncogene family
chr4_-_186696425 5.42 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
sorbin and SH3 domain containing 2
chr11_-_35441597 5.36 ENST00000395753.1
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr19_-_14316980 5.31 ENST00000361434.3
ENST00000340736.6
latrophilin 1
chr1_+_226411319 5.30 ENST00000542034.1
ENST00000366810.5
Mix paired-like homeobox
chr1_+_89990431 5.11 ENST00000330947.2
ENST00000358200.4
leucine rich repeat containing 8 family, member B
chr1_-_233431458 5.06 ENST00000258229.9
ENST00000430153.1
pecanex-like 2 (Drosophila)
chr10_+_1102721 5.03 ENST00000263150.4
WD repeat domain 37
chr15_+_74833518 4.93 ENST00000346246.5
AT rich interactive domain 3B (BRIGHT-like)
chr1_-_84464780 4.86 ENST00000260505.8
tubulin tyrosine ligase-like family, member 7
chr10_+_18429671 4.84 ENST00000282343.8
calcium channel, voltage-dependent, beta 2 subunit
chr6_+_126112001 4.81 ENST00000392477.2
nuclear receptor coactivator 7
chr21_+_34697258 4.77 ENST00000442071.1
ENST00000442357.2
interferon (alpha, beta and omega) receptor 1
chr2_+_17935119 4.76 ENST00000317402.7
GEN1 Holliday junction 5' flap endonuclease
chr7_+_99613212 4.72 ENST00000426572.1
ENST00000535170.1
zinc finger with KRAB and SCAN domains 1
chr7_+_72848092 4.71 ENST00000344575.3
frizzled family receptor 9
chr19_-_47164386 4.65 ENST00000391916.2
ENST00000410105.2
dishevelled-binding antagonist of beta-catenin 3
chr20_+_49575342 4.58 ENST00000244051.1
molybdenum cofactor synthesis 3
chr2_+_11052054 4.56 ENST00000295082.1
potassium voltage-gated channel, subfamily F, member 1
chr6_+_30851840 4.56 ENST00000511510.1
ENST00000376569.3
ENST00000376575.3
ENST00000376570.4
ENST00000446312.1
ENST00000504927.1
discoidin domain receptor tyrosine kinase 1
chr17_-_73401728 4.43 ENST00000316804.5
ENST00000316615.5
growth factor receptor-bound protein 2
chr5_+_118788182 4.43 ENST00000515320.1
ENST00000510025.1
hydroxysteroid (17-beta) dehydrogenase 4
chr21_+_40752170 4.41 ENST00000333781.5
ENST00000541890.1
tryptophan rich basic protein
chr17_-_31620006 4.39 ENST00000225823.2
acid-sensing (proton-gated) ion channel 2
chrX_-_107018969 4.35 ENST00000372383.4
TSC22 domain family, member 3
chr19_+_5904866 4.33 ENST00000339485.3
vimentin-type intermediate filament associated coiled-coil protein
chr12_+_107168342 4.33 ENST00000392837.4
RIC8 guanine nucleotide exchange factor B
chr5_-_19988339 4.29 ENST00000382275.1
cadherin 18, type 2
chr19_+_12949251 4.28 ENST00000251472.4
microtubule associated serine/threonine kinase 1
chr2_+_65283506 4.27 ENST00000377990.2
centrosomal protein 68kDa
chr12_+_57984965 4.27 ENST00000540759.2
ENST00000551772.1
ENST00000550465.1
ENST00000354947.5
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr17_+_47653178 4.26 ENST00000328741.5
neurexophilin 3
chr1_+_44115814 4.23 ENST00000372396.3
lysine (K)-specific demethylase 4A
chr2_-_230135937 4.21 ENST00000392054.3
ENST00000409462.1
ENST00000392055.3
phosphotyrosine interaction domain containing 1
chr22_-_20850070 4.18 ENST00000440659.2
ENST00000458248.1
ENST00000443285.1
ENST00000444967.1
ENST00000451553.1
ENST00000431430.1
kelch-like family member 22
chr6_+_37012607 4.11 ENST00000423336.1
cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2
chr5_+_118788261 4.05 ENST00000504811.1
hydroxysteroid (17-beta) dehydrogenase 4
chr14_-_45603657 4.05 ENST00000396062.3
FK506 binding protein 3, 25kDa
chr1_+_24969755 4.05 ENST00000447431.2
ENST00000374389.4
serine/arginine repetitive matrix 1
chr2_+_231902193 4.03 ENST00000373640.4
chromosome 2 open reading frame 72
chr4_+_62066941 4.00 ENST00000512091.2
latrophilin 3
chr1_+_156124162 3.99 ENST00000368282.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr16_+_19222479 3.97 ENST00000568433.1
synaptotagmin XVII
chr7_+_99613195 3.95 ENST00000324306.6
zinc finger with KRAB and SCAN domains 1
chr6_-_154831779 3.92 ENST00000607772.1
CNKSR family member 3
chr4_+_176986978 3.92 ENST00000508596.1
ENST00000393643.2
WD repeat domain 17
chr5_-_133747589 3.88 ENST00000458198.2
CDKN2A interacting protein N-terminal like
chr12_-_120554622 3.86 ENST00000229340.5
RAB35, member RAS oncogene family
chr19_-_45996465 3.84 ENST00000430715.2
reticulon 2
chr2_+_8822113 3.84 ENST00000396290.1
ENST00000331129.3
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr1_-_153919128 3.82 ENST00000361217.4
DENN/MADD domain containing 4B
chr1_+_202317815 3.81 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
protein phosphatase 1, regulatory subunit 12B
chr10_-_98945677 3.80 ENST00000266058.4
ENST00000371041.3
slit homolog 1 (Drosophila)
chr10_+_92980517 3.79 ENST00000336126.5
polycomb group ring finger 5
chr8_-_125740514 3.78 ENST00000325064.5
ENST00000518547.1
metastasis suppressor 1
chr1_-_237167718 3.78 ENST00000464121.2
metallothionein 1H-like 1
chr6_+_26156551 3.76 ENST00000304218.3
histone cluster 1, H1e
chr19_-_54327542 3.76 ENST00000391775.3
ENST00000324134.6
ENST00000535162.1
ENST00000351894.4
ENST00000354278.3
ENST00000391773.1
ENST00000345770.5
ENST00000391772.1
NLR family, pyrin domain containing 12
chr5_-_16936340 3.76 ENST00000507288.1
ENST00000513610.1
myosin X
chr2_-_202316260 3.74 ENST00000332624.3
trafficking protein, kinesin binding 2
chr17_-_73401567 3.69 ENST00000392562.1
growth factor receptor-bound protein 2
chr2_-_9563319 3.68 ENST00000497105.1
ENST00000360635.3
ENST00000359712.3
integrin beta 1 binding protein 1
chr9_+_125703282 3.65 ENST00000373647.4
ENST00000402311.1
RAB GTPase activating protein 1
chr14_-_104313824 3.55 ENST00000553739.1
ENST00000202556.9
protein phosphatase 1, regulatory subunit 13B
chr10_+_18689637 3.54 ENST00000377315.4
calcium channel, voltage-dependent, beta 2 subunit
chr2_+_236578248 3.51 ENST00000409538.1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr1_-_85156090 3.51 ENST00000605755.1
ENST00000437941.2
synovial sarcoma, X breakpoint 2 interacting protein
chr2_+_65283529 3.51 ENST00000546106.1
ENST00000537589.1
ENST00000260569.4
centrosomal protein 68kDa
chr5_+_118788433 3.50 ENST00000414835.2
hydroxysteroid (17-beta) dehydrogenase 4
chr19_-_460996 3.47 ENST00000264554.6
SHC (Src homology 2 domain containing) transforming protein 2
chr5_+_118788138 3.47 ENST00000256216.6
hydroxysteroid (17-beta) dehydrogenase 4
chr12_+_122064398 3.45 ENST00000330079.7
ORAI calcium release-activated calcium modulator 1
chr10_+_12391481 3.43 ENST00000378847.3
calcium/calmodulin-dependent protein kinase ID
chr20_+_8112824 3.40 ENST00000378641.3
phospholipase C, beta 1 (phosphoinositide-specific)
chr19_-_3061397 3.39 ENST00000586839.1
amino-terminal enhancer of split
chr19_+_7598890 3.39 ENST00000221249.6
ENST00000601668.1
ENST00000601001.1
patatin-like phospholipase domain containing 6
chr14_+_24583836 3.35 ENST00000559115.1
ENST00000558215.1
ENST00000557810.1
ENST00000561375.1
ENST00000446197.3
ENST00000559796.1
ENST00000560713.1
ENST00000560901.1
ENST00000559382.1
DDB1 and CUL4 associated factor 11

Network of associatons between targets according to the STRING database.

First level regulatory network of NHLH1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
37.2 111.5 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
15.9 47.8 GO:0033693 neurofilament bundle assembly(GO:0033693)
11.4 34.1 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
10.3 41.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
9.6 28.9 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
9.0 44.8 GO:0030382 sperm mitochondrion organization(GO:0030382)
5.9 17.6 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
5.3 15.9 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
3.9 27.3 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
3.7 11.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
3.6 14.5 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
3.5 10.6 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
3.4 10.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
3.1 25.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
2.9 14.7 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
2.9 8.6 GO:0042938 dipeptide transport(GO:0042938)
2.6 13.1 GO:0021759 globus pallidus development(GO:0021759)
2.6 13.0 GO:1902075 cellular response to salt(GO:1902075)
2.6 15.4 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
2.5 7.5 GO:0003358 noradrenergic neuron development(GO:0003358)
2.3 22.6 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
2.0 10.1 GO:1990034 calcium ion export from cell(GO:1990034)
1.9 9.4 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
1.9 7.5 GO:0046502 uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
1.8 12.4 GO:0002175 protein localization to paranode region of axon(GO:0002175)
1.7 49.2 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
1.6 14.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
1.6 4.7 GO:1990523 negative regulation of neuromuscular junction development(GO:1904397) bone regeneration(GO:1990523)
1.6 31.0 GO:0006706 steroid catabolic process(GO:0006706)
1.5 4.6 GO:0018307 enzyme active site formation(GO:0018307) tRNA thio-modification(GO:0034227)
1.5 12.1 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.4 22.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
1.4 4.2 GO:0090298 negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
1.4 8.4 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
1.3 10.6 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
1.3 9.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
1.2 3.7 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
1.2 5.0 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
1.2 3.7 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
1.2 4.7 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
1.1 3.4 GO:0090427 activation of meiosis(GO:0090427)
1.1 4.5 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
1.1 14.4 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
1.1 21.3 GO:0035493 SNARE complex assembly(GO:0035493)
1.0 6.3 GO:0018095 protein polyglutamylation(GO:0018095)
1.0 5.1 GO:2000382 positive regulation of mesoderm development(GO:2000382)
1.0 2.9 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
1.0 6.9 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
1.0 2.9 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.9 3.8 GO:0032661 Toll signaling pathway(GO:0008063) regulation of interleukin-18 production(GO:0032661)
0.9 2.8 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.9 5.6 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.9 8.0 GO:0009408 response to heat(GO:0009408) cellular response to heat(GO:0034605)
0.8 3.3 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072) negative regulation of protein kinase C signaling(GO:0090038)
0.8 9.2 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.8 3.3 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.8 2.5 GO:0051054 positive regulation of DNA metabolic process(GO:0051054)
0.8 2.3 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.8 3.8 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
0.8 9.8 GO:0061162 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.8 20.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.7 4.4 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.7 5.1 GO:0071494 cellular response to UV-C(GO:0071494)
0.7 2.2 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.7 11.4 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.7 5.7 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.7 6.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.7 17.0 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.7 5.3 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.6 1.9 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.6 3.8 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.6 3.8 GO:0030035 microspike assembly(GO:0030035)
0.6 4.4 GO:0050915 sensory perception of sour taste(GO:0050915)
0.6 2.5 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.6 8.1 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.6 6.1 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.6 4.2 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.6 7.8 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.6 1.7 GO:0090611 mitotic cytokinesis checkpoint(GO:0044878) ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.6 5.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.6 2.8 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.6 3.4 GO:0071233 cellular response to leucine(GO:0071233) cellular response to leucine starvation(GO:1990253)
0.6 2.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.5 2.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.5 2.7 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115) malonyl-CoA metabolic process(GO:2001293)
0.5 3.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.5 9.6 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.5 4.6 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.5 6.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.5 1.0 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.5 1.4 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.5 3.8 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.5 3.7 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.5 5.5 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.4 12.5 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.4 4.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.4 2.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.4 1.7 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
0.4 1.2 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.4 6.0 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.4 9.9 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.4 0.8 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.4 1.2 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.4 1.1 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.3 7.3 GO:0007625 grooming behavior(GO:0007625)
0.3 1.4 GO:0060023 soft palate development(GO:0060023)
0.3 1.4 GO:0032811 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.3 24.3 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.3 11.1 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.3 3.3 GO:0046548 retinal rod cell development(GO:0046548)
0.3 4.6 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.3 2.0 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.3 1.0 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.3 1.3 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.3 3.4 GO:2000210 positive regulation of anoikis(GO:2000210)
0.3 14.5 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.3 4.8 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.3 13.4 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.3 3.0 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.3 1.2 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.3 13.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.3 1.4 GO:0086045 membrane depolarization during AV node cell action potential(GO:0086045)
0.3 1.4 GO:0035865 cellular response to potassium ion(GO:0035865)
0.3 4.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.3 16.8 GO:0051865 protein autoubiquitination(GO:0051865)
0.3 16.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.3 1.8 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.2 1.7 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.2 2.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.2 8.4 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.2 3.3 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.2 3.7 GO:0048820 hair follicle maturation(GO:0048820)
0.2 2.3 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.2 1.4 GO:0042426 choline catabolic process(GO:0042426)
0.2 2.3 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2 1.9 GO:0002115 store-operated calcium entry(GO:0002115)
0.2 2.9 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.2 1.0 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.2 1.9 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.2 3.9 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.2 2.0 GO:0045176 apical protein localization(GO:0045176)
0.2 2.5 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.2 1.7 GO:0034501 protein localization to kinetochore(GO:0034501)
0.2 0.5 GO:0071109 superior temporal gyrus development(GO:0071109)
0.2 6.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 1.5 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1 0.6 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 11.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 0.8 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1 0.7 GO:0035936 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.1 0.3 GO:0071288 cellular response to mercury ion(GO:0071288)
0.1 2.9 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.1 3.4 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 2.0 GO:0002021 response to dietary excess(GO:0002021)
0.1 1.6 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.5 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 4.2 GO:0071173 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.1 0.5 GO:0007498 mesoderm development(GO:0007498)
0.1 2.3 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.1 3.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 4.0 GO:0009725 response to hormone(GO:0009725)
0.1 2.1 GO:0006828 manganese ion transport(GO:0006828)
0.1 1.2 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.1 0.4 GO:0032900 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) negative regulation of neurotrophin production(GO:0032900) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 4.0 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 1.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 2.2 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.1 0.5 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 6.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 2.1 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 0.9 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 1.1 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.1 2.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.9 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 2.0 GO:0014047 glutamate secretion(GO:0014047)
0.1 0.7 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 1.9 GO:0045730 respiratory burst(GO:0045730)
0.1 4.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 3.0 GO:0048536 spleen development(GO:0048536)
0.1 0.1 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 14.9 GO:0046718 viral entry into host cell(GO:0046718)
0.1 4.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 25.1 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.1 1.5 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 3.2 GO:0008333 endosome to lysosome transport(GO:0008333)
0.1 4.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.4 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 6.1 GO:1901216 positive regulation of neuron death(GO:1901216)
0.1 0.8 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 0.5 GO:0015853 adenine transport(GO:0015853)
0.1 0.5 GO:0007623 circadian rhythm(GO:0007623)
0.1 5.0 GO:1904590 negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein import(GO:1904590)
0.1 1.3 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.1 0.7 GO:0048266 behavioral response to pain(GO:0048266)
0.1 3.8 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 4.0 GO:0006906 vesicle fusion(GO:0006906)
0.1 2.1 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.1 8.6 GO:0007626 locomotory behavior(GO:0007626)
0.1 1.4 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.1 1.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 3.5 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 1.2 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 1.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.9 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 2.6 GO:0006470 protein dephosphorylation(GO:0006470)
0.1 3.8 GO:0065002 intracellular protein transmembrane transport(GO:0065002)
0.1 4.5 GO:0051301 cell division(GO:0051301)
0.1 0.5 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.1 0.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.7 GO:0042753 cell differentiation in hindbrain(GO:0021533) cerebellar Purkinje cell layer formation(GO:0021694) cerebellar cortex formation(GO:0021697) cerebellar Purkinje cell differentiation(GO:0021702) positive regulation of circadian rhythm(GO:0042753)
0.1 6.7 GO:0044070 regulation of anion transport(GO:0044070)
0.1 2.7 GO:0006040 amino sugar metabolic process(GO:0006040)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0 0.2 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0 0.1 GO:0044065 regulation of respiratory system process(GO:0044065)
0.0 2.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 1.3 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.0 1.6 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 7.2 GO:0010976 positive regulation of neuron projection development(GO:0010976)
0.0 0.2 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 22.8 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.3 GO:0031175 neuron projection development(GO:0031175)
0.0 2.4 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.9 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 1.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.3 GO:0097192 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 1.0 GO:0009311 oligosaccharide metabolic process(GO:0009311)
0.0 0.6 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 2.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:1901160 primary amino compound metabolic process(GO:1901160)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0006388 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 1.2 GO:0006641 triglyceride metabolic process(GO:0006641)
0.0 0.1 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 1.0 GO:0045666 positive regulation of neuron differentiation(GO:0045666)
0.0 0.4 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.5 GO:0006937 regulation of muscle contraction(GO:0006937)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 75.1 GO:0005883 neurofilament(GO:0005883)
3.2 28.9 GO:0005955 calcineurin complex(GO:0005955)
3.2 44.8 GO:0097227 sperm annulus(GO:0097227)
2.8 2.8 GO:0005683 U7 snRNP(GO:0005683)
2.2 41.3 GO:0097386 glial cell projection(GO:0097386)
2.1 14.7 GO:0002178 palmitoyltransferase complex(GO:0002178)
2.0 34.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
1.5 6.0 GO:0032044 DSIF complex(GO:0032044)
1.4 2.9 GO:0097539 ciliary transition fiber(GO:0097539)
1.4 11.1 GO:0060203 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
1.4 8.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
1.3 22.7 GO:0005687 U4 snRNP(GO:0005687)
1.2 36.2 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
1.1 5.7 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
1.1 22.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
1.1 12.4 GO:0033270 paranode region of axon(GO:0033270)
1.1 10.6 GO:0045180 basal cortex(GO:0045180)
0.8 10.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.6 5.5 GO:0005827 polar microtubule(GO:0005827)
0.6 49.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.6 57.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.6 1.7 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.6 3.4 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.6 3.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.5 10.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.5 3.8 GO:0014802 terminal cisterna(GO:0014802)
0.5 13.0 GO:0030673 axolemma(GO:0030673)
0.5 3.3 GO:0072487 MSL complex(GO:0072487)
0.4 6.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.4 10.6 GO:0016580 Sin3 complex(GO:0016580)
0.3 18.2 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3 44.4 GO:0043204 perikaryon(GO:0043204)
0.3 3.7 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.3 1.2 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.3 3.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.3 45.0 GO:0000922 spindle pole(GO:0000922)
0.3 5.2 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.2 1.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.2 8.2 GO:0031527 filopodium membrane(GO:0031527)
0.2 18.4 GO:0014704 intercalated disc(GO:0014704)
0.2 6.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 1.4 GO:0070545 PeBoW complex(GO:0070545)
0.2 1.9 GO:0032010 phagolysosome(GO:0032010)
0.2 3.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 1.6 GO:0016272 prefoldin complex(GO:0016272)
0.2 4.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2 1.1 GO:1990037 Lewy body core(GO:1990037)
0.2 4.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.2 1.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 9.7 GO:0005902 microvillus(GO:0005902)
0.1 6.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 3.8 GO:0030139 endocytic vesicle(GO:0030139)
0.1 8.5 GO:0043195 terminal bouton(GO:0043195)
0.1 10.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 3.0 GO:0030057 desmosome(GO:0030057)
0.1 27.3 GO:0005802 trans-Golgi network(GO:0005802)
0.1 0.7 GO:0097165 nuclear stress granule(GO:0097165)
0.1 2.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 16.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 2.9 GO:0034451 centriolar satellite(GO:0034451)
0.1 4.1 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.1 2.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 1.0 GO:0033391 chromatoid body(GO:0033391)
0.1 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 27.1 GO:0005769 early endosome(GO:0005769)
0.1 7.5 GO:0043202 lysosomal lumen(GO:0043202)
0.1 0.5 GO:1990909 Wnt signalosome(GO:1990909)
0.1 4.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 6.1 GO:0005814 centriole(GO:0005814)
0.1 0.9 GO:0005686 U2 snRNP(GO:0005686)
0.1 2.2 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.7 GO:0000812 Swr1 complex(GO:0000812)
0.1 47.2 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 0.2 GO:0070695 FHF complex(GO:0070695)
0.1 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 1.0 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 7.9 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 0.6 GO:0043296 apical junction complex(GO:0043296)
0.1 7.7 GO:0001650 fibrillar center(GO:0001650)
0.0 1.4 GO:0043679 axon terminus(GO:0043679)
0.0 3.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 3.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.7 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 14.4 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 2.1 GO:0005776 autophagosome(GO:0005776)
0.0 0.8 GO:0032040 small-subunit processome(GO:0032040)
0.0 3.3 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 27.5 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.9 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.5 GO:0046930 pore complex(GO:0046930)
0.0 3.4 GO:0043209 myelin sheath(GO:0043209)
0.0 7.7 GO:0005813 centrosome(GO:0005813)
0.0 3.0 GO:0070062 extracellular exosome(GO:0070062)
0.0 4.7 GO:0005874 microtubule(GO:0005874)
0.0 2.3 GO:0005815 microtubule organizing center(GO:0005815)
0.0 0.3 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 1.8 GO:0030133 transport vesicle(GO:0030133)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0042611 MHC protein complex(GO:0042611) MHC class II protein complex(GO:0042613)
0.0 0.5 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
37.2 111.5 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
11.4 34.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
10.3 41.3 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
3.6 14.5 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
2.9 28.9 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
2.9 14.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
2.9 14.4 GO:0016403 dimethylargininase activity(GO:0016403)
2.8 11.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
2.6 15.4 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
2.2 50.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
2.0 20.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
1.9 5.7 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
1.7 12.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.5 4.6 GO:0019961 interferon binding(GO:0019961)
1.5 8.9 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
1.4 4.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
1.3 10.6 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
1.3 6.3 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
1.2 9.8 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
1.2 4.7 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
1.1 6.9 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
1.1 22.5 GO:0008603 cAMP-dependent protein kinase inhibitor activity(GO:0004862) cAMP-dependent protein kinase regulator activity(GO:0008603)
1.1 27.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
1.1 8.6 GO:0004064 arylesterase activity(GO:0004064)
1.0 10.1 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
1.0 14.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
1.0 5.7 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.9 2.8 GO:0071209 U7 snRNA binding(GO:0071209)
0.9 24.3 GO:0031489 myosin V binding(GO:0031489)
0.9 4.6 GO:0070097 delta-catenin binding(GO:0070097)
0.9 2.8 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.9 4.4 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.9 10.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.8 9.1 GO:0051430 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.8 11.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.8 3.2 GO:0017040 ceramidase activity(GO:0017040)
0.8 7.9 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.8 4.6 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.6 22.1 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.6 3.8 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.6 10.6 GO:0002162 dystroglycan binding(GO:0002162)
0.6 107.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.6 8.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.6 5.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.6 5.6 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.5 3.3 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.5 2.0 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.5 21.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.5 3.7 GO:0019863 immunoglobulin receptor activity(GO:0019763) IgE binding(GO:0019863)
0.5 6.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.5 1.4 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.4 3.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.4 11.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.4 3.8 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.4 2.9 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.4 1.2 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.4 3.3 GO:0048495 Roundabout binding(GO:0048495)
0.4 1.4 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.3 10.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.3 4.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.3 12.1 GO:0017091 AU-rich element binding(GO:0017091)
0.3 1.3 GO:0001855 complement component C4b binding(GO:0001855)
0.3 1.0 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.3 2.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.3 2.8 GO:0043426 MRF binding(GO:0043426)
0.3 0.9 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.3 3.3 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.3 4.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.3 0.8 GO:0033149 FFAT motif binding(GO:0033149)
0.3 76.9 GO:0003924 GTPase activity(GO:0003924)
0.3 3.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.2 6.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 8.6 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.2 3.7 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 4.0 GO:0038191 neuropilin binding(GO:0038191)
0.2 3.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.2 39.6 GO:0044325 ion channel binding(GO:0044325)
0.2 2.0 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.2 5.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 2.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 3.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.2 6.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 1.3 GO:0070064 proline-rich region binding(GO:0070064)
0.2 1.7 GO:1990405 protein antigen binding(GO:1990405)
0.2 3.3 GO:0015929 hexosaminidase activity(GO:0015929)
0.2 2.8 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.2 2.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.2 19.2 GO:0001618 virus receptor activity(GO:0001618)
0.2 4.0 GO:0050811 GABA receptor binding(GO:0050811)
0.2 5.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 3.8 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.2 1.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 2.2 GO:0036122 BMP binding(GO:0036122)
0.2 0.9 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.2 2.0 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2 4.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 3.8 GO:0003785 actin monomer binding(GO:0003785)
0.2 18.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 1.0 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 3.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 1.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 7.7 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 5.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 3.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 1.3 GO:0043422 protein kinase B binding(GO:0043422)
0.1 1.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 1.1 GO:0003696 satellite DNA binding(GO:0003696)
0.1 0.8 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 7.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 1.8 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.3 GO:0005112 Notch binding(GO:0005112)
0.1 1.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 9.6 GO:0020037 heme binding(GO:0020037)
0.1 0.2 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.1 2.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 3.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 4.0 GO:0030276 clathrin binding(GO:0030276)
0.1 17.3 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 4.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 0.5 GO:0015288 porin activity(GO:0015288)
0.1 1.0 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 0.7 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.6 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 0.7 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 3.5 GO:0019843 rRNA binding(GO:0019843)
0.1 4.3 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 7.0 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 0.3 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.1 1.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 3.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 3.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 7.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 12.3 GO:0008017 microtubule binding(GO:0008017)
0.0 0.9 GO:0015278 intracellular ligand-gated ion channel activity(GO:0005217) calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.2 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 1.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 2.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 2.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 10.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 1.2 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.6 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 3.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 4.6 GO:0019901 protein kinase binding(GO:0019901)
0.0 1.7 GO:0051117 ATPase binding(GO:0051117)
0.0 1.1 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 3.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.5 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.1 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.0 1.0 GO:0051082 unfolded protein binding(GO:0051082)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 111.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.8 52.0 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.6 10.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.6 28.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.6 3.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.4 12.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.3 18.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.3 16.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.3 19.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.3 4.6 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.3 3.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.3 15.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.3 20.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.3 6.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.2 1.7 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.2 5.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 4.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 3.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.2 3.4 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 3.5 PID RAS PATHWAY Regulation of Ras family activation
0.1 2.3 PID CONE PATHWAY Visual signal transduction: Cones
0.1 1.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 21.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 3.7 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 10.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 2.9 PID LKB1 PATHWAY LKB1 signaling events
0.1 3.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 5.0 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.8 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 2.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 2.2 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 1.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 0.6 PID SHP2 PATHWAY SHP2 signaling
0.0 0.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 111.5 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
3.2 67.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
2.4 23.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
1.3 35.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
1.2 15.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
1.0 35.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
1.0 50.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.8 3.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.8 5.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.8 21.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.7 10.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.6 8.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.6 10.6 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.6 19.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.6 15.6 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.6 11.6 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.4 4.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.4 11.5 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.4 4.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.3 15.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.3 8.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.3 6.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.3 7.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 3.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.3 3.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 4.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 4.0 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 4.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 3.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 8.1 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.2 2.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 10.4 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.2 3.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.2 7.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 7.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.2 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.1 2.9 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 2.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 1.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 3.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 4.5 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 7.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 16.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 3.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 2.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 8.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 2.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.6 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 4.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.4 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.7 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 2.7 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0 1.9 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 4.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 1.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.6 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 1.1 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events