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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for NKX6-2

Z-value: 0.87

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Transcription factors associated with NKX6-2

Gene Symbol Gene ID Gene Info
NKX6-2
ENSG00000148826.6 NK6 homeobox 2

Activity profile of NKX6-2 motif

Sorted Z-values of NKX6-2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_60097524 35.81 ENST00000342503.4
RTN1
reticulon 1
chr17_-_42992856 33.65 ENST00000588316.1
ENST00000435360.2
ENST00000586793.1
ENST00000588735.1
ENST00000588037.1
ENST00000592320.1
ENST00000253408.5
GFAP
glial fibrillary acidic protein
chr3_+_39509163 31.12 ENST00000436143.2
ENST00000441980.2
ENST00000311042.6
MOBP
myelin-associated oligodendrocyte basic protein
chr4_+_41258786 29.25 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr3_+_39509070 29.22 ENST00000354668.4
ENST00000428261.1
ENST00000420739.1
ENST00000415443.1
ENST00000447324.1
ENST00000383754.3
MOBP
myelin-associated oligodendrocyte basic protein
chr14_-_60097297 28.58 ENST00000395090.1
RTN1
reticulon 1
chr3_-_98241358 21.58 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
CLDND1
claudin domain containing 1
chr2_-_175712270 20.58 ENST00000295497.7
ENST00000444394.1
CHN1
chimerin 1
chr10_-_73848086 17.05 ENST00000536168.1
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr4_+_88896819 16.05 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
SPP1
secreted phosphoprotein 1
chr22_+_29138013 13.98 ENST00000216027.3
ENST00000398941.2
HSCB
HscB mitochondrial iron-sulfur cluster co-chaperone
chr9_-_93405352 13.55 ENST00000375765.3
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr7_-_37024665 12.83 ENST00000396040.2
ELMO1
engulfment and cell motility 1
chr10_-_73848531 12.47 ENST00000373109.2
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr7_-_137028534 11.78 ENST00000348225.2
PTN
pleiotrophin
chr2_+_233527443 11.66 ENST00000410095.1
EFHD1
EF-hand domain family, member D1
chr14_-_27066960 11.25 ENST00000539517.2
NOVA1
neuro-oncological ventral antigen 1
chr7_-_137028498 10.76 ENST00000393083.2
PTN
pleiotrophin
chr4_-_87374283 10.74 ENST00000361569.2
MAPK10
mitogen-activated protein kinase 10
chr5_+_161275320 10.61 ENST00000437025.2
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr9_+_82186872 10.46 ENST00000376544.3
ENST00000376520.4
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr19_+_52772821 9.93 ENST00000439461.1
ZNF766
zinc finger protein 766
chr17_+_57232690 9.77 ENST00000262293.4
PRR11
proline rich 11
chr7_+_77325738 9.74 ENST00000334955.8
RSBN1L
round spermatid basic protein 1-like
chr12_-_6233828 9.56 ENST00000572068.1
ENST00000261405.5
VWF
von Willebrand factor
chr2_-_73520667 9.15 ENST00000545030.1
ENST00000436467.2
EGR4
early growth response 4
chrX_+_135230712 8.87 ENST00000535737.1
FHL1
four and a half LIM domains 1
chr14_-_98444386 8.74 ENST00000556462.1
ENST00000556138.1
C14orf64
chromosome 14 open reading frame 64
chr18_-_52989217 8.60 ENST00000570287.2
TCF4
transcription factor 4
chr19_+_52772832 8.53 ENST00000593703.1
ENST00000601711.1
ENST00000599581.1
ZNF766
zinc finger protein 766
chr17_-_73663168 8.53 ENST00000578201.1
ENST00000423245.2
RECQL5
RecQ protein-like 5
chr16_-_4852915 8.26 ENST00000322048.7
ROGDI
rogdi homolog (Drosophila)
chr10_-_71169031 8.15 ENST00000373307.1
TACR2
tachykinin receptor 2
chr7_+_16828866 7.99 ENST00000597084.1
AC073333.1
Uncharacterized protein
chr1_-_226926864 7.62 ENST00000429204.1
ENST00000366784.1
ITPKB
inositol-trisphosphate 3-kinase B
chr17_+_72581057 7.61 ENST00000392620.1
C17orf77
chromosome 17 open reading frame 77
chr5_+_161274940 7.49 ENST00000393943.4
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr2_+_68962014 7.38 ENST00000467265.1
ARHGAP25
Rho GTPase activating protein 25
chr12_+_32655048 7.35 ENST00000427716.2
ENST00000266482.3
FGD4
FYVE, RhoGEF and PH domain containing 4
chr1_-_149858227 7.25 ENST00000369155.2
HIST2H2BE
histone cluster 2, H2be
chr5_+_161274685 7.01 ENST00000428797.2
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr8_+_79428539 6.84 ENST00000352966.5
PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr1_+_229440129 6.37 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr1_+_115397424 6.19 ENST00000369522.3
ENST00000455987.1
SYCP1
synaptonemal complex protein 1
chr17_-_73663245 6.16 ENST00000584999.1
ENST00000317905.5
ENST00000420326.2
ENST00000340830.5
RECQL5
RecQ protein-like 5
chr16_+_14802801 5.86 ENST00000526520.1
ENST00000531598.2
NPIPA3
nuclear pore complex interacting protein family, member A3
chr19_+_12175504 5.84 ENST00000439326.3
ZNF844
zinc finger protein 844
chr5_-_20575959 5.73 ENST00000507958.1
CDH18
cadherin 18, type 2
chr5_+_67586465 5.71 ENST00000336483.5
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr5_-_58295712 5.69 ENST00000317118.8
PDE4D
phosphodiesterase 4D, cAMP-specific
chr6_+_31582961 5.64 ENST00000376059.3
ENST00000337917.7
AIF1
allograft inflammatory factor 1
chr3_+_159557637 5.63 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr16_+_31128978 5.35 ENST00000448516.2
ENST00000219797.4
KAT8
K(lysine) acetyltransferase 8
chr14_-_27066636 5.30 ENST00000267422.7
ENST00000344429.5
ENST00000574031.1
ENST00000465357.2
ENST00000547619.1
NOVA1
neuro-oncological ventral antigen 1
chr16_+_14841923 5.25 ENST00000530328.1
ENST00000529166.1
NPIPA2
nuclear pore complex interacting protein family, member A2
chr5_+_161495038 5.06 ENST00000393933.4
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr18_+_76829385 4.98 ENST00000426216.2
ENST00000307671.7
ENST00000586672.1
ENST00000586722.1
ATP9B
ATPase, class II, type 9B
chr11_-_62521614 4.97 ENST00000527994.1
ENST00000394807.3
ZBTB3
zinc finger and BTB domain containing 3
chr1_+_50459990 4.95 ENST00000448346.1
AL645730.2
AL645730.2
chr2_-_217559517 4.66 ENST00000449583.1
IGFBP5
insulin-like growth factor binding protein 5
chr18_+_76829441 4.65 ENST00000458297.2
ATP9B
ATPase, class II, type 9B
chr1_+_180601139 4.64 ENST00000367590.4
ENST00000367589.3
XPR1
xenotropic and polytropic retrovirus receptor 1
chrX_+_10124977 4.63 ENST00000380833.4
CLCN4
chloride channel, voltage-sensitive 4
chr5_-_55412774 4.59 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr3_-_114790179 4.58 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr18_-_52989525 4.50 ENST00000457482.3
TCF4
transcription factor 4
chr6_+_26402517 4.49 ENST00000414912.2
BTN3A1
butyrophilin, subfamily 3, member A1
chr10_+_26505179 4.38 ENST00000376261.3
GAD2
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
chr9_-_23826298 4.38 ENST00000380117.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr19_+_54641444 4.35 ENST00000221232.5
ENST00000358389.3
CNOT3
CCR4-NOT transcription complex, subunit 3
chrX_-_48901012 4.35 ENST00000315869.7
TFE3
transcription factor binding to IGHM enhancer 3
chr7_-_22233442 4.28 ENST00000401957.2
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr4_+_55095264 4.25 ENST00000257290.5
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr15_-_49103235 3.96 ENST00000380950.2
CEP152
centrosomal protein 152kDa
chr18_+_32290218 3.82 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
DTNA
dystrobrevin, alpha
chr7_+_138943265 3.71 ENST00000483726.1
UBN2
ubinuclein 2
chr8_+_104831472 3.67 ENST00000262231.10
ENST00000507740.1
RIMS2
regulating synaptic membrane exocytosis 2
chrX_+_55744166 3.61 ENST00000374941.4
ENST00000414239.1
RRAGB
Ras-related GTP binding B
chr6_+_158733692 3.61 ENST00000367094.2
ENST00000367097.3
TULP4
tubby like protein 4
chr18_+_13218769 3.56 ENST00000399848.3
ENST00000361205.4
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr9_-_23825956 3.55 ENST00000397312.2
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr1_+_209878182 3.43 ENST00000367027.3
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr15_-_49103184 3.43 ENST00000399334.3
ENST00000325747.5
CEP152
centrosomal protein 152kDa
chr7_-_140482926 3.29 ENST00000496384.2
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr2_+_218990727 3.22 ENST00000318507.2
ENST00000454148.1
CXCR2
chemokine (C-X-C motif) receptor 2
chr2_+_210444142 3.17 ENST00000360351.4
ENST00000361559.4
MAP2
microtubule-associated protein 2
chr2_-_74570520 3.13 ENST00000394019.2
ENST00000346834.4
ENST00000359484.4
ENST00000423644.1
ENST00000377634.4
ENST00000436454.1
SLC4A5
solute carrier family 4 (sodium bicarbonate cotransporter), member 5
chr1_-_49242553 3.07 ENST00000371833.3
BEND5
BEN domain containing 5
chr2_-_228244013 3.05 ENST00000304568.3
TM4SF20
transmembrane 4 L six family member 20
chr3_-_45838011 3.05 ENST00000358525.4
ENST00000413781.1
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chrX_+_102840408 3.05 ENST00000468024.1
ENST00000472484.1
ENST00000415568.2
ENST00000490644.1
ENST00000459722.1
ENST00000472745.1
ENST00000494801.1
ENST00000434216.2
ENST00000425011.1
TCEAL4
transcription elongation factor A (SII)-like 4
chr2_-_217560248 3.05 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr5_+_7373230 2.99 ENST00000500616.2
CTD-2296D1.5
CTD-2296D1.5
chr19_+_15852203 2.78 ENST00000305892.1
OR10H3
olfactory receptor, family 10, subfamily H, member 3
chrX_+_68835911 2.76 ENST00000525810.1
ENST00000527388.1
ENST00000374553.2
ENST00000374552.4
ENST00000338901.3
ENST00000524573.1
EDA
ectodysplasin A
chrX_+_55744228 2.67 ENST00000262850.7
RRAGB
Ras-related GTP binding B
chr2_+_202047843 2.61 ENST00000272879.5
ENST00000374650.3
ENST00000346817.5
ENST00000313728.7
ENST00000448480.1
CASP10
caspase 10, apoptosis-related cysteine peptidase
chr10_-_100995540 2.52 ENST00000370546.1
ENST00000404542.1
HPSE2
heparanase 2
chr9_-_110540419 2.48 ENST00000398726.3
AL162389.1
Uncharacterized protein
chr21_-_36421535 2.38 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
RUNX1
runt-related transcription factor 1
chr16_+_31271274 2.34 ENST00000287497.8
ENST00000544665.3
ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
chr14_-_101295407 2.28 ENST00000596284.1
AL117190.2
AL117190.2
chr3_-_45837959 2.25 ENST00000353278.4
ENST00000456124.2
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chrX_+_82763265 2.24 ENST00000373200.2
POU3F4
POU class 3 homeobox 4
chr3_+_178276488 2.22 ENST00000432997.1
ENST00000455865.1
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr6_-_26199471 2.22 ENST00000341023.1
HIST1H2AD
histone cluster 1, H2ad
chr10_-_100995603 2.20 ENST00000370552.3
ENST00000370549.1
HPSE2
heparanase 2
chr6_-_46703430 2.19 ENST00000537365.1
PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr6_+_26402465 2.19 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1
butyrophilin, subfamily 3, member A1
chr8_-_82395461 2.15 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chr21_-_36421626 2.12 ENST00000300305.3
RUNX1
runt-related transcription factor 1
chr18_-_10701979 2.04 ENST00000538948.1
ENST00000285141.4
PIEZO2
piezo-type mechanosensitive ion channel component 2
chr20_-_18477862 2.03 ENST00000337227.4
RBBP9
retinoblastoma binding protein 9
chr17_-_40828969 1.96 ENST00000591022.1
ENST00000587627.1
ENST00000293349.6
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr10_-_115904361 1.95 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chr5_-_146258205 1.94 ENST00000394413.3
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr1_+_70820451 1.92 ENST00000361764.4
ENST00000359875.5
ENST00000370940.5
ENST00000531950.1
ENST00000432224.1
HHLA3
HERV-H LTR-associating 3
chr12_+_9980069 1.89 ENST00000354855.3
ENST00000324214.4
ENST00000279544.3
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr10_+_32873190 1.80 ENST00000375025.4
C10orf68
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr17_-_40829026 1.69 ENST00000412503.1
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr18_+_61575200 1.66 ENST00000238508.3
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr2_-_136873735 1.63 ENST00000409817.1
CXCR4
chemokine (C-X-C motif) receptor 4
chr8_-_91095099 1.62 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr9_+_82187630 1.54 ENST00000265284.6
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr2_+_68961934 1.52 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr21_-_27462351 1.50 ENST00000448850.1
APP
amyloid beta (A4) precursor protein
chr2_+_68961905 1.48 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr22_-_40929812 1.35 ENST00000422851.1
MKL1
megakaryoblastic leukemia (translocation) 1
chr1_-_200379129 1.30 ENST00000367353.1
ZNF281
zinc finger protein 281
chr1_+_196621002 1.29 ENST00000367429.4
ENST00000439155.2
CFH
complement factor H
chr15_+_93443419 1.28 ENST00000557381.1
ENST00000420239.2
CHD2
chromodomain helicase DNA binding protein 2
chr14_-_99737565 1.28 ENST00000357195.3
BCL11B
B-cell CLL/lymphoma 11B (zinc finger protein)
chr8_+_24298531 1.17 ENST00000175238.6
ADAM7
ADAM metallopeptidase domain 7
chr7_-_107880508 1.16 ENST00000425651.2
NRCAM
neuronal cell adhesion molecule
chr7_+_143657027 1.16 ENST00000392899.1
OR2F1
olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
chr6_-_26199499 1.15 ENST00000377831.5
HIST1H3D
histone cluster 1, H3d
chr8_+_24298597 1.15 ENST00000380789.1
ADAM7
ADAM metallopeptidase domain 7
chr3_+_130650738 1.13 ENST00000504612.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr4_+_100495864 1.10 ENST00000265517.5
ENST00000422897.2
MTTP
microsomal triglyceride transfer protein
chr20_+_42136308 0.95 ENST00000434666.1
ENST00000427442.2
ENST00000439769.1
ENST00000418998.1
L3MBTL1
l(3)mbt-like 1 (Drosophila)
chr10_+_48189612 0.94 ENST00000453919.1
AGAP9
ArfGAP with GTPase domain, ankyrin repeat and PH domain 9
chr12_+_25205568 0.90 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr1_-_190446759 0.87 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr22_-_39268192 0.83 ENST00000216083.6
CBX6
chromobox homolog 6
chr5_+_31193847 0.82 ENST00000514738.1
ENST00000265071.2
CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr13_-_33760216 0.71 ENST00000255486.4
STARD13
StAR-related lipid transfer (START) domain containing 13
chr19_+_4402659 0.70 ENST00000301280.5
ENST00000585854.1
CHAF1A
chromatin assembly factor 1, subunit A (p150)
chr5_-_111091948 0.65 ENST00000447165.2
NREP
neuronal regeneration related protein
chr1_+_32379174 0.63 ENST00000391369.1
AL136115.1
HCG2032337; PRO1848; Uncharacterized protein
chr15_-_89764929 0.59 ENST00000268125.5
RLBP1
retinaldehyde binding protein 1
chr14_+_72399833 0.47 ENST00000553530.1
ENST00000556437.1
RGS6
regulator of G-protein signaling 6
chr4_-_110723194 0.46 ENST00000394635.3
CFI
complement factor I
chr6_-_26043885 0.44 ENST00000357905.2
HIST1H2BB
histone cluster 1, H2bb
chr4_+_169418255 0.41 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr1_-_150849174 0.39 ENST00000515192.1
ARNT
aryl hydrocarbon receptor nuclear translocator
chr2_-_208030647 0.32 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr13_+_97928395 0.32 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr6_+_25963020 0.30 ENST00000357085.3
TRIM38
tripartite motif containing 38
chr21_-_36421401 0.26 ENST00000486278.2
RUNX1
runt-related transcription factor 1
chr22_+_24198890 0.24 ENST00000345044.6
SLC2A11
solute carrier family 2 (facilitated glucose transporter), member 11
chr6_+_41021027 0.21 ENST00000244669.2
APOBEC2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr19_+_852291 0.17 ENST00000263621.1
ELANE
elastase, neutrophil expressed
chr22_-_39268308 0.17 ENST00000407418.3
CBX6
chromobox homolog 6
chr1_+_174933899 0.16 ENST00000367688.3
RABGAP1L
RAB GTPase activating protein 1-like
chr16_+_28565230 0.16 ENST00000317058.3
CCDC101
coiled-coil domain containing 101
chr2_+_169757750 0.02 ENST00000375363.3
ENST00000429379.2
ENST00000421979.1
G6PC2
glucose-6-phosphatase, catalytic, 2

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX6-2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
9.8 29.3 GO:0007412 axon target recognition(GO:0007412)
7.5 22.5 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
5.3 16.0 GO:0035937 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
4.9 14.7 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
4.0 60.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
2.7 8.2 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
2.6 7.7 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
2.3 14.0 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
1.6 30.6 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
1.5 30.2 GO:0071420 cellular response to histamine(GO:0071420)
1.4 4.2 GO:0072277 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
1.4 29.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
1.3 10.7 GO:0007258 JUN phosphorylation(GO:0007258)
1.2 7.4 GO:0098535 de novo centriole assembly(GO:0098535)
1.1 5.6 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
1.1 7.6 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029) common myeloid progenitor cell proliferation(GO:0035726)
1.1 3.2 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
1.0 6.3 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.8 5.3 GO:0015824 proline transport(GO:0015824)
0.7 4.4 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.7 6.2 GO:0051026 chiasma assembly(GO:0051026)
0.7 4.6 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.7 3.3 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.6 5.7 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.6 3.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.6 20.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.5 2.8 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.4 2.2 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.4 6.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.4 9.6 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.4 4.8 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.4 7.3 GO:0002227 innate immune response in mucosa(GO:0002227)
0.4 9.8 GO:0007050 cell cycle arrest(GO:0007050)
0.4 5.7 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.4 5.4 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.3 12.8 GO:0016601 Rac protein signal transduction(GO:0016601)
0.3 9.6 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.3 1.3 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.3 1.5 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.3 3.6 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.3 6.7 GO:0072643 interferon-gamma secretion(GO:0072643)
0.2 1.6 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.2 11.9 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.2 1.9 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.2 1.6 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.2 4.3 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.2 1.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 1.4 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.2 1.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.2 2.2 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.2 2.3 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.2 8.9 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.2 3.4 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 0.7 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 2.1 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 2.2 GO:0005513 detection of calcium ion(GO:0005513)
0.1 1.1 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 8.3 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.1 4.6 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.1 3.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 2.0 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.1 4.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 3.6 GO:0061512 protein localization to cilium(GO:0061512)
0.1 3.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 4.3 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.1 4.6 GO:0046847 filopodium assembly(GO:0046847)
0.1 24.8 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.1 0.2 GO:1903238 positive regulation of leukocyte tethering or rolling(GO:1903238)
0.1 1.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 3.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 1.0 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.6 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 6.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 3.1 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.3 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 10.4 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 4.7 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 0.9 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.0 2.6 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 12.0 GO:0031175 neuron projection development(GO:0031175)
0.0 3.9 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 1.3 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 7.5 GO:0045666 positive regulation of neuron differentiation(GO:0045666)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.4 GO:0098536 deuterosome(GO:0098536)
1.4 5.7 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
1.2 6.2 GO:0000801 central element(GO:0000801)
1.1 12.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
1.0 6.3 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.9 30.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.9 7.7 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.8 5.4 GO:0072487 MSL complex(GO:0072487)
0.6 29.3 GO:1904115 axon cytoplasm(GO:1904115)
0.5 3.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.5 54.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.5 2.3 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.5 5.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.4 4.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.4 64.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.4 4.4 GO:0060077 inhibitory synapse(GO:0060077)
0.3 5.6 GO:0001891 phagocytic cup(GO:0001891)
0.2 19.6 GO:0031594 neuromuscular junction(GO:0031594)
0.2 0.7 GO:0033186 CAF-1 complex(GO:0033186)
0.1 2.6 GO:0097342 ripoptosome(GO:0097342)
0.1 16.4 GO:0005882 intermediate filament(GO:0005882)
0.1 5.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 2.8 GO:0005581 collagen trimer(GO:0005581)
0.1 1.2 GO:0043194 axon initial segment(GO:0043194)
0.1 3.2 GO:0042629 mast cell granule(GO:0042629)
0.1 2.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 33.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 3.7 GO:0000786 nucleosome(GO:0000786)
0.1 7.5 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.1 8.2 GO:0031901 early endosome membrane(GO:0031901)
0.1 13.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 3.0 GO:0005902 microvillus(GO:0005902)
0.0 4.6 GO:0030175 filopodium(GO:0030175)
0.0 2.9 GO:0005811 lipid particle(GO:0005811)
0.0 4.3 GO:0032993 protein-DNA complex(GO:0032993)
0.0 5.8 GO:0005635 nuclear envelope(GO:0005635)
0.0 1.6 GO:0043195 terminal bouton(GO:0043195)
0.0 9.4 GO:0005743 mitochondrial inner membrane(GO:0005743) organelle inner membrane(GO:0019866)
0.0 3.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 8.4 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.7 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 2.2 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 7.3 GO:0005925 focal adhesion(GO:0005925)
0.0 0.9 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 1.0 GO:0031519 PcG protein complex(GO:0031519)
0.0 10.3 GO:0009986 cell surface(GO:0009986)
0.0 0.6 GO:0044297 cell body(GO:0044297)
0.0 1.3 GO:0072562 blood microparticle(GO:0072562)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.3 29.3 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
5.6 22.5 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
5.0 60.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
3.1 25.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
2.4 14.7 GO:0009378 four-way junction helicase activity(GO:0009378)
1.8 10.7 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.6 8.2 GO:0004995 tachykinin receptor activity(GO:0004995)
1.4 4.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
1.3 7.6 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
1.2 29.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
1.2 4.7 GO:0030305 heparanase activity(GO:0030305)
1.2 4.6 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
1.1 3.4 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
1.1 3.2 GO:0019959 interleukin-8 binding(GO:0019959)
1.0 13.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.7 7.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.6 4.4 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.6 5.7 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.5 2.6 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.4 5.4 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.4 20.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.4 14.0 GO:0001671 ATPase activator activity(GO:0001671)
0.4 5.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.4 9.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.3 6.8 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.3 2.0 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.3 4.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.3 0.9 GO:0032093 SAM domain binding(GO:0032093)
0.3 5.7 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.3 9.6 GO:0019865 immunoglobulin binding(GO:0019865)
0.3 2.2 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.3 1.6 GO:0005499 vitamin D binding(GO:0005499)
0.3 5.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.2 15.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 2.3 GO:0001851 complement component C3b binding(GO:0001851)
0.2 3.2 GO:0002162 dystroglycan binding(GO:0002162)
0.2 4.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 1.6 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.2 3.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 30.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 1.5 GO:0051425 PTB domain binding(GO:0051425)
0.2 2.8 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 0.6 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 2.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 11.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 3.3 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 1.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.7 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 24.5 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 2.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 12.8 GO:0017124 SH3 domain binding(GO:0017124)
0.1 3.6 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.2 GO:0003680 AT DNA binding(GO:0003680)
0.1 7.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 1.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 3.1 GO:0050699 WW domain binding(GO:0050699)
0.1 4.8 GO:0001047 core promoter binding(GO:0001047)
0.1 1.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 2.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.9 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 1.1 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 1.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 1.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 11.4 GO:0003924 GTPase activity(GO:0003924)
0.0 11.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 5.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 2.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 16.5 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.0 GO:0003727 single-stranded RNA binding(GO:0003727)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 7.6 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.6 19.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.5 29.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.5 29.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.5 33.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.5 28.9 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.4 16.0 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.4 3.2 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.2 4.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 20.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 2.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 17.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 4.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 1.6 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 3.2 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.9 PID ATR PATHWAY ATR signaling pathway
0.0 8.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 3.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.4 PID RHOA PATHWAY RhoA signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 30.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.6 9.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.5 10.7 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.5 33.6 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.3 1.6 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.3 5.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.3 7.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 12.8 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.2 12.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 5.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 39.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.2 13.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.2 10.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.2 11.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2 3.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.2 6.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.2 2.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.2 18.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 2.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 4.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 3.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 4.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 2.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 5.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 3.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 1.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 3.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 1.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 2.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 3.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 4.2 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 2.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 4.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 3.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters