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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
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Results for UUGGUCC
Z-value: 0.34
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miRNA associated with seed UUGGUCC
Network of associatons between targets according to the STRING database.
First level regulatory network of UUGGUCC
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 7.3 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
| 2.3 | 6.8 | GO:0098746 | fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746) |
| 0.3 | 6.7 | GO:0032011 | ARF protein signal transduction(GO:0032011) |
| 0.1 | 6.6 | GO:0042073 | intraciliary transport(GO:0042073) |
| 2.1 | 6.3 | GO:0070318 | positive regulation of G0 to G1 transition(GO:0070318) |
| 0.6 | 6.2 | GO:0090232 | peripheral nervous system myelin maintenance(GO:0032287) positive regulation of spindle checkpoint(GO:0090232) |
| 0.5 | 6.1 | GO:0060137 | maternal process involved in parturition(GO:0060137) |
| 0.4 | 5.7 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 0.1 | 5.5 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.1 | 5.5 | GO:0055072 | iron ion homeostasis(GO:0055072) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 8.7 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.4 | 8.5 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.1 | 8.4 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 1.4 | 6.8 | GO:0060201 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
| 0.0 | 6.2 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.1 | 5.9 | GO:0097542 | ciliary tip(GO:0097542) |
| 1.1 | 5.6 | GO:0098843 | postsynaptic endocytic zone(GO:0098843) |
| 0.0 | 5.5 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 5.3 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.1 | 4.8 | GO:0005801 | cis-Golgi network(GO:0005801) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 6.8 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 0.1 | 6.6 | GO:0005262 | calcium channel activity(GO:0005262) |
| 1.3 | 6.4 | GO:0035252 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 0.2 | 6.3 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.2 | 6.2 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.2 | 6.2 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.2 | 6.2 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.2 | 5.7 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.5 | 5.6 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 0.0 | 5.6 | GO:0017137 | Rab GTPase binding(GO:0017137) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 8.9 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.2 | 8.5 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.1 | 7.5 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.1 | 6.3 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.0 | 4.8 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 4.7 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 4.6 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 4.2 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 3.4 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.1 | 3.1 | PID REELIN PATHWAY | Reelin signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 9.7 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.2 | 5.6 | REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.1 | 5.1 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.1 | 4.6 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.2 | 4.3 | REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.0 | 3.9 | REACTOME G ALPHA S SIGNALLING EVENTS | Genes involved in G alpha (s) signalling events |
| 0.1 | 3.7 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.2 | 3.3 | REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 | Genes involved in Signaling by activated point mutants of FGFR1 |
| 0.0 | 3.2 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.2 | 3.1 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |