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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for ZNF784

Z-value: 1.76

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Transcription factors associated with ZNF784

Gene Symbol Gene ID Gene Info
ZNF784
ENSG00000179922.5 zinc finger protein 784

Activity profile of ZNF784 motif

Sorted Z-values of ZNF784 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_195310802 59.82 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr3_-_42306248 43.51 ENST00000334681.5
CCK
cholecystokinin
chr11_-_5248294 42.88 ENST00000335295.4
HBB
hemoglobin, beta
chr19_-_42498369 41.85 ENST00000302102.5
ENST00000545399.1
ATP1A3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr19_-_42498231 41.06 ENST00000602133.1
ATP1A3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr4_+_158141806 40.43 ENST00000393815.2
GRIA2
glutamate receptor, ionotropic, AMPA 2
chr4_+_158142750 40.29 ENST00000505888.1
ENST00000449365.1
GRIA2
glutamate receptor, ionotropic, AMPA 2
chr11_+_73358594 40.16 ENST00000227214.6
ENST00000398494.4
ENST00000543085.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr8_+_80523321 39.85 ENST00000518111.1
STMN2
stathmin-like 2
chr4_+_158141843 39.31 ENST00000509417.1
ENST00000296526.7
GRIA2
glutamate receptor, ionotropic, AMPA 2
chr4_+_158141899 36.84 ENST00000264426.9
ENST00000506284.1
GRIA2
glutamate receptor, ionotropic, AMPA 2
chr12_-_91572278 27.37 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
DCN
decorin
chr20_+_44036620 26.97 ENST00000372710.3
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr4_-_90758118 26.95 ENST00000420646.2
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr9_-_139094988 25.58 ENST00000371746.3
LHX3
LIM homeobox 3
chr3_+_50712672 23.93 ENST00000266037.9
DOCK3
dedicator of cytokinesis 3
chr11_-_6440283 23.70 ENST00000299402.6
ENST00000609360.1
ENST00000389906.2
ENST00000532020.2
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr11_-_6440624 23.03 ENST00000311051.3
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr10_-_93392811 22.99 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr4_-_90758227 22.20 ENST00000506691.1
ENST00000394986.1
ENST00000506244.1
ENST00000394989.2
ENST00000394991.3
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr15_+_25200108 20.93 ENST00000577949.1
ENST00000338094.6
ENST00000338327.4
ENST00000579070.1
ENST00000577565.1
SNURF
SNRPN
SNRPN upstream reading frame protein
small nuclear ribonucleoprotein polypeptide N
chr6_+_151042224 20.83 ENST00000358517.2
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr11_-_134281812 20.40 ENST00000392580.1
ENST00000312527.4
B3GAT1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr3_-_47619623 20.28 ENST00000456150.1
CSPG5
chondroitin sulfate proteoglycan 5 (neuroglycan C)
chr5_-_74062930 20.24 ENST00000509430.1
ENST00000345239.2
ENST00000427854.2
ENST00000506778.1
GFM2
G elongation factor, mitochondrial 2
chr8_-_9008206 20.03 ENST00000310455.3
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr5_-_149535421 19.93 ENST00000261799.4
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr2_-_85839146 19.56 ENST00000306336.5
ENST00000409734.3
C2orf68
chromosome 2 open reading frame 68
chr2_-_68384603 19.53 ENST00000406245.2
ENST00000409164.1
ENST00000295121.6
WDR92
WD repeat domain 92
chr12_-_66524482 19.26 ENST00000446587.2
ENST00000266604.2
LLPH
LLP homolog, long-term synaptic facilitation (Aplysia)
chrX_-_54384425 18.80 ENST00000375169.3
ENST00000354646.2
WNK3
WNK lysine deficient protein kinase 3
chr10_+_92980517 18.58 ENST00000336126.5
PCGF5
polycomb group ring finger 5
chr12_-_91573249 18.08 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN
decorin
chr20_+_44036900 17.70 ENST00000443296.1
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr6_-_150039249 17.45 ENST00000543571.1
LATS1
large tumor suppressor kinase 1
chr19_-_57988871 17.16 ENST00000596831.1
ENST00000601768.1
ENST00000356584.3
ENST00000600175.1
ENST00000425074.3
ENST00000343280.4
ENST00000427512.2
AC004076.9
ZNF772
Uncharacterized protein
zinc finger protein 772
chr1_+_50575292 16.99 ENST00000371821.1
ENST00000371819.1
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr18_-_21852143 16.89 ENST00000399443.3
OSBPL1A
oxysterol binding protein-like 1A
chr5_+_161274940 16.87 ENST00000393943.4
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr3_-_51994694 16.28 ENST00000395014.2
PCBP4
poly(rC) binding protein 4
chr18_-_5419797 16.14 ENST00000542146.1
ENST00000427684.2
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr10_+_82168240 15.91 ENST00000372187.5
ENST00000372185.1
FAM213A
family with sequence similarity 213, member A
chr10_-_127511790 15.59 ENST00000368797.4
ENST00000420761.1
UROS
uroporphyrinogen III synthase
chr4_+_48833234 15.44 ENST00000510824.1
ENST00000425583.2
OCIAD1
OCIA domain containing 1
chr1_+_50574585 15.41 ENST00000371824.1
ENST00000371823.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr11_-_62389449 14.76 ENST00000534026.1
B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr2_-_11272234 14.06 ENST00000590207.1
ENST00000417697.2
ENST00000396164.1
ENST00000536743.1
ENST00000544306.1
AC062028.1
AC062028.1
chr3_+_45067659 13.85 ENST00000296130.4
CLEC3B
C-type lectin domain family 3, member B
chr17_-_74707037 13.78 ENST00000355797.3
ENST00000375036.2
ENST00000449428.2
MXRA7
matrix-remodelling associated 7
chr22_+_42196666 13.54 ENST00000402061.3
ENST00000255784.5
CCDC134
coiled-coil domain containing 134
chr17_-_36956155 13.15 ENST00000269554.3
PIP4K2B
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr9_-_79307096 13.15 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
PRUNE2
prune homolog 2 (Drosophila)
chr4_+_41362796 12.85 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIMCH1
LIM and calponin homology domains 1
chr8_-_9009079 12.81 ENST00000519699.1
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr4_-_130692631 12.76 ENST00000500092.2
ENST00000509105.1
RP11-519M16.1
RP11-519M16.1
chrX_-_6146876 12.67 ENST00000381095.3
NLGN4X
neuroligin 4, X-linked
chr4_-_90756769 12.46 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr4_+_37455536 12.31 ENST00000381980.4
ENST00000508175.1
C4orf19
chromosome 4 open reading frame 19
chr1_-_203320617 12.29 ENST00000354955.4
FMOD
fibromodulin
chr5_+_161275320 12.27 ENST00000437025.2
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr5_+_137225158 12.06 ENST00000290431.5
PKD2L2
polycystic kidney disease 2-like 2
chr4_+_48833119 12.01 ENST00000444354.2
ENST00000509963.1
ENST00000509246.1
OCIAD1
OCIA domain containing 1
chr9_-_115480303 11.80 ENST00000374234.1
ENST00000374238.1
ENST00000374236.1
ENST00000374242.4
INIP
INTS3 and NABP interacting protein
chr5_+_140729649 11.59 ENST00000523390.1
PCDHGB1
protocadherin gamma subfamily B, 1
chr7_-_103629963 11.26 ENST00000428762.1
ENST00000343529.5
ENST00000424685.2
RELN
reelin
chr2_-_127864839 11.15 ENST00000409400.1
ENST00000357970.3
ENST00000393040.3
ENST00000348750.4
ENST00000259238.4
ENST00000346226.3
ENST00000393041.3
ENST00000351659.3
ENST00000352848.3
ENST00000316724.5
BIN1
bridging integrator 1
chr3_-_9834375 11.15 ENST00000343450.2
ENST00000301964.2
TADA3
transcriptional adaptor 3
chr3_-_122512619 11.11 ENST00000383659.1
ENST00000306103.2
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr11_+_65154070 11.01 ENST00000317568.5
ENST00000531296.1
ENST00000533782.1
ENST00000355991.5
ENST00000416776.2
ENST00000526201.1
FRMD8
FERM domain containing 8
chr4_+_6202448 10.90 ENST00000508601.1
RP11-586D19.1
RP11-586D19.1
chr14_+_29241910 10.87 ENST00000399387.4
ENST00000552957.1
ENST00000548213.1
C14orf23
chromosome 14 open reading frame 23
chr4_-_90757364 10.81 ENST00000508895.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr17_+_77020325 10.73 ENST00000311661.4
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr3_+_183993797 10.55 ENST00000359140.4
ENST00000404464.3
ENST00000357474.5
ECE2
endothelin converting enzyme 2
chr8_+_85095497 10.55 ENST00000522455.1
ENST00000521695.1
RALYL
RALY RNA binding protein-like
chr17_+_42264556 10.24 ENST00000319511.6
ENST00000589785.1
ENST00000592825.1
ENST00000589184.1
TMUB2
transmembrane and ubiquitin-like domain containing 2
chr11_-_115375107 10.21 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1
cell adhesion molecule 1
chr5_-_174871136 10.09 ENST00000393752.2
DRD1
dopamine receptor D1
chr2_-_25873079 10.05 ENST00000496972.2
DTNB
dystrobrevin, beta
chr4_+_71263599 9.98 ENST00000399575.2
PROL1
proline rich, lacrimal 1
chrX_-_154842589 9.95 ENST00000334398.3
TMLHE
trimethyllysine hydroxylase, epsilon
chr4_+_62066941 9.81 ENST00000512091.2
LPHN3
latrophilin 3
chr17_+_77020224 9.47 ENST00000339142.2
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr22_+_20067738 9.47 ENST00000351989.3
ENST00000383024.2
DGCR8
DGCR8 microprocessor complex subunit
chr8_+_11561660 9.44 ENST00000526716.1
ENST00000335135.4
ENST00000528027.1
GATA4
GATA binding protein 4
chr3_+_197476621 9.40 ENST00000241502.4
FYTTD1
forty-two-three domain containing 1
chr15_+_89346657 9.28 ENST00000439576.2
ACAN
aggrecan
chr17_+_10600894 9.27 ENST00000379774.4
ADPRM
ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
chr19_+_3880581 9.24 ENST00000450849.2
ENST00000301260.6
ENST00000398448.3
ATCAY
ataxia, cerebellar, Cayman type
chr5_-_178772424 9.23 ENST00000251582.7
ENST00000274609.5
ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr22_-_44708731 9.15 ENST00000381176.4
KIAA1644
KIAA1644
chr8_-_57358432 9.10 ENST00000517415.1
ENST00000314922.3
PENK
proenkephalin
chr17_+_19281034 9.09 ENST00000308406.5
ENST00000299612.7
MAPK7
mitogen-activated protein kinase 7
chr4_-_10686475 9.08 ENST00000226951.6
CLNK
cytokine-dependent hematopoietic cell linker
chr19_+_49622646 8.99 ENST00000334186.4
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr11_-_74109422 8.91 ENST00000298198.4
PGM2L1
phosphoglucomutase 2-like 1
chr1_-_154155675 8.85 ENST00000330188.9
ENST00000341485.5
TPM3
tropomyosin 3
chr19_+_13858593 8.68 ENST00000221554.8
CCDC130
coiled-coil domain containing 130
chr7_-_97881429 8.62 ENST00000420697.1
ENST00000379795.3
ENST00000415086.1
ENST00000542604.1
ENST00000447648.2
TECPR1
tectonin beta-propeller repeat containing 1
chr6_+_123100620 8.60 ENST00000368444.3
FABP7
fatty acid binding protein 7, brain
chr16_+_19179549 8.51 ENST00000355377.2
ENST00000568115.1
SYT17
synaptotagmin XVII
chr21_-_36421535 8.45 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
RUNX1
runt-related transcription factor 1
chr1_-_153029980 8.35 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr1_+_205012293 8.34 ENST00000331830.4
CNTN2
contactin 2 (axonal)
chr1_+_171283331 8.29 ENST00000367749.3
FMO4
flavin containing monooxygenase 4
chr5_+_137225125 8.24 ENST00000350250.4
ENST00000508638.1
ENST00000502810.1
ENST00000508883.1
PKD2L2
polycystic kidney disease 2-like 2
chr4_-_153274078 8.09 ENST00000263981.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr3_+_195447738 7.98 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
MUC20
mucin 20, cell surface associated
chr12_-_14996355 7.94 ENST00000228936.4
ART4
ADP-ribosyltransferase 4 (Dombrock blood group)
chr20_+_20348740 7.94 ENST00000310227.1
INSM1
insulinoma-associated 1
chr1_-_85156090 7.94 ENST00000605755.1
ENST00000437941.2
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr9_-_99381660 7.91 ENST00000375240.3
ENST00000463569.1
CDC14B
cell division cycle 14B
chr1_+_205473720 7.48 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
CDK18
cyclin-dependent kinase 18
chr11_-_19262486 7.47 ENST00000250024.4
E2F8
E2F transcription factor 8
chr22_+_25202232 7.46 ENST00000400358.4
ENST00000400359.4
SGSM1
small G protein signaling modulator 1
chr11_+_5009424 7.38 ENST00000300762.1
MMP26
matrix metallopeptidase 26
chr13_-_96705624 7.38 ENST00000376747.3
ENST00000376712.4
ENST00000397618.3
ENST00000376714.3
UGGT2
UDP-glucose glycoprotein glucosyltransferase 2
chr21_-_36421626 7.38 ENST00000300305.3
RUNX1
runt-related transcription factor 1
chrX_+_49593853 7.35 ENST00000376141.1
PAGE4
P antigen family, member 4 (prostate associated)
chr3_+_124303472 7.16 ENST00000291478.5
KALRN
kalirin, RhoGEF kinase
chr6_-_46922659 7.11 ENST00000265417.7
GPR116
G protein-coupled receptor 116
chrX_+_49593888 7.09 ENST00000218068.6
PAGE4
P antigen family, member 4 (prostate associated)
chr9_-_99382065 7.09 ENST00000265659.2
ENST00000375241.1
ENST00000375236.1
CDC14B
cell division cycle 14B
chr12_+_100661156 6.90 ENST00000360820.2
SCYL2
SCY1-like 2 (S. cerevisiae)
chr20_-_56286479 6.89 ENST00000265626.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chrX_-_55024967 6.53 ENST00000545676.1
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr1_+_203651937 6.41 ENST00000341360.2
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr19_-_15236173 6.34 ENST00000527093.1
ILVBL
ilvB (bacterial acetolactate synthase)-like
chr12_+_52445191 6.32 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr3_-_39321512 6.27 ENST00000399220.2
CX3CR1
chemokine (C-X3-C motif) receptor 1
chr7_+_119913688 6.14 ENST00000331113.4
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr5_+_112073544 5.97 ENST00000257430.4
ENST00000508376.2
APC
adenomatous polyposis coli
chr5_-_159827073 5.85 ENST00000408953.3
C5orf54
chromosome 5 open reading frame 54
chr11_-_62389621 5.83 ENST00000531383.1
ENST00000265471.5
B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr2_-_73869508 5.82 ENST00000272425.3
NAT8
N-acetyltransferase 8 (GCN5-related, putative)
chr15_-_55657428 5.72 ENST00000568543.1
CCPG1
cell cycle progression 1
chr4_+_71226468 5.59 ENST00000226460.4
SMR3A
submaxillary gland androgen regulated protein 3A
chr16_+_2564254 5.49 ENST00000565223.1
ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr19_+_50879705 5.42 ENST00000598168.1
ENST00000411902.2
ENST00000253727.5
ENST00000597790.1
ENST00000597130.1
ENST00000599105.1
NR1H2
nuclear receptor subfamily 1, group H, member 2
chr11_+_1861399 5.37 ENST00000381905.3
TNNI2
troponin I type 2 (skeletal, fast)
chr18_-_31802056 5.32 ENST00000538587.1
NOL4
nucleolar protein 4
chr6_-_100912785 5.29 ENST00000369208.3
SIM1
single-minded family bHLH transcription factor 1
chr14_+_105452094 5.29 ENST00000551606.1
ENST00000547315.1
C14orf79
chromosome 14 open reading frame 79
chr18_-_31802282 5.20 ENST00000535475.1
NOL4
nucleolar protein 4
chr5_-_159827033 5.17 ENST00000523213.1
C5orf54
chromosome 5 open reading frame 54
chr1_+_20465805 5.09 ENST00000375102.3
PLA2G2F
phospholipase A2, group IIF
chr18_+_905104 5.05 ENST00000579794.1
ADCYAP1
adenylate cyclase activating polypeptide 1 (pituitary)
chr1_-_85156216 5.03 ENST00000342203.3
ENST00000370612.4
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr20_+_57414795 4.96 ENST00000371098.2
ENST00000371075.3
GNAS
GNAS complex locus
chr1_+_165600436 4.91 ENST00000367888.4
ENST00000367885.1
ENST00000367884.2
MGST3
microsomal glutathione S-transferase 3
chr2_-_70780770 4.90 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
TGFA
transforming growth factor, alpha
chr7_+_26332645 4.90 ENST00000396376.1
SNX10
sorting nexin 10
chr1_+_3607228 4.84 ENST00000378285.1
ENST00000378280.1
ENST00000378288.4
TP73
tumor protein p73
chrY_+_16636354 4.82 ENST00000339174.5
NLGN4Y
neuroligin 4, Y-linked
chr11_-_10590118 4.71 ENST00000529598.1
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr3_+_124303539 4.71 ENST00000428018.2
KALRN
kalirin, RhoGEF kinase
chr17_-_50237343 4.68 ENST00000575181.1
ENST00000570565.1
CA10
carbonic anhydrase X
chr17_+_73717407 4.68 ENST00000579662.1
ITGB4
integrin, beta 4
chr20_-_56285595 4.66 ENST00000395816.3
ENST00000347215.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr3_-_48130314 4.64 ENST00000439356.1
ENST00000395734.3
ENST00000426837.2
MAP4
microtubule-associated protein 4
chr4_+_6784401 4.57 ENST00000425103.1
ENST00000307659.5
KIAA0232
KIAA0232
chr1_-_115238207 4.55 ENST00000520113.2
ENST00000369538.3
ENST00000353928.6
AMPD1
adenosine monophosphate deaminase 1
chr1_+_32042131 4.54 ENST00000271064.7
ENST00000537531.1
TINAGL1
tubulointerstitial nephritis antigen-like 1
chr9_-_127533519 4.52 ENST00000487099.2
ENST00000344523.4
ENST00000373584.3
NR6A1
nuclear receptor subfamily 6, group A, member 1
chr1_-_175161890 4.47 ENST00000545251.2
ENST00000423313.1
KIAA0040
KIAA0040
chr18_-_45457192 4.41 ENST00000586514.1
ENST00000591214.1
ENST00000589877.1
SMAD2
SMAD family member 2
chr12_-_96390063 4.40 ENST00000541929.1
HAL
histidine ammonia-lyase
chr19_-_376011 4.34 ENST00000342640.4
THEG
theg spermatid protein
chr13_-_33760216 4.31 ENST00000255486.4
STARD13
StAR-related lipid transfer (START) domain containing 13
chr1_+_165600083 4.27 ENST00000367889.3
MGST3
microsomal glutathione S-transferase 3
chr9_+_136325089 4.22 ENST00000291722.7
ENST00000316948.4
ENST00000540581.1
CACFD1
calcium channel flower domain containing 1
chr19_+_39936186 4.15 ENST00000432763.2
ENST00000402194.2
ENST00000601515.1
SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr7_+_131012605 4.14 ENST00000446815.1
ENST00000352689.6
MKLN1
muskelin 1, intracellular mediator containing kelch motifs
chr12_+_50497784 4.09 ENST00000548814.1
GPD1
glycerol-3-phosphate dehydrogenase 1 (soluble)
chr21_-_35831880 4.07 ENST00000399289.3
ENST00000432085.1
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr17_+_73717551 4.07 ENST00000450894.3
ITGB4
integrin, beta 4
chr12_+_54402790 4.06 ENST00000040584.4
HOXC8
homeobox C8
chr3_-_48130707 3.99 ENST00000360240.6
ENST00000383737.4
MAP4
microtubule-associated protein 4
chr12_-_48119301 3.99 ENST00000545824.2
ENST00000422538.3
ENDOU
endonuclease, polyU-specific
chr2_-_56150910 3.97 ENST00000424836.2
ENST00000438672.1
ENST00000440439.1
ENST00000429909.1
ENST00000424207.1
ENST00000452337.1
ENST00000355426.3
ENST00000439193.1
ENST00000421664.1
EFEMP1
EGF containing fibulin-like extracellular matrix protein 1
chr11_+_89867681 3.93 ENST00000534061.1
NAALAD2
N-acetylated alpha-linked acidic dipeptidase 2
chr1_+_32042105 3.85 ENST00000457433.2
ENST00000441210.2
TINAGL1
tubulointerstitial nephritis antigen-like 1
chrY_+_16634483 3.85 ENST00000382872.1
NLGN4Y
neuroligin 4, Y-linked
chr4_-_187476721 3.79 ENST00000307161.5
MTNR1A
melatonin receptor 1A
chr12_-_96390108 3.60 ENST00000538703.1
ENST00000261208.3
HAL
histidine ammonia-lyase
chr21_-_36421401 3.59 ENST00000486278.2
RUNX1
runt-related transcription factor 1
chr6_+_136172820 3.56 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr21_+_41029235 3.55 ENST00000380618.1
B3GALT5
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
chr3_+_139654018 3.54 ENST00000458420.3
CLSTN2
calsyntenin 2
chr1_-_92951607 3.51 ENST00000427103.1
GFI1
growth factor independent 1 transcription repressor
chr4_+_71248795 3.49 ENST00000304915.3
SMR3B
submaxillary gland androgen regulated protein 3B
chr6_-_161695042 3.45 ENST00000366908.5
ENST00000366911.5
ENST00000366905.3
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr17_-_1394940 3.41 ENST00000570984.2
ENST00000361007.2
MYO1C
myosin IC
chrX_+_153686614 3.40 ENST00000369682.3
PLXNA3
plexin A3
chr2_+_45878790 3.40 ENST00000306156.3
PRKCE
protein kinase C, epsilon
chr2_+_198669365 3.39 ENST00000428675.1
PLCL1
phospholipase C-like 1
chrX_-_57163430 3.35 ENST00000374908.1
SPIN2A
spindlin family, member 2A
chr17_-_19281203 3.24 ENST00000487415.2
B9D1
B9 protein domain 1
chr6_-_161695074 3.19 ENST00000457520.2
ENST00000366906.5
ENST00000320285.4
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr7_+_128577972 3.13 ENST00000357234.5
ENST00000477535.1
ENST00000479582.1
ENST00000464557.1
ENST00000402030.2
IRF5
interferon regulatory factor 5

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF784

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
19.9 59.8 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
15.6 46.7 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
14.5 72.4 GO:0051945 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
10.7 42.9 GO:0030185 nitric oxide transport(GO:0030185)
10.4 82.9 GO:0060075 regulation of resting membrane potential(GO:0060075)
10.0 39.9 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
6.6 19.9 GO:0060437 lung growth(GO:0060437) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
5.4 43.5 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
5.1 20.2 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
4.7 18.8 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
4.3 25.6 GO:0021523 somatic motor neuron differentiation(GO:0021523)
4.1 12.3 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
3.9 15.6 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
3.9 15.6 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
3.8 45.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
3.6 21.3 GO:0097105 presynaptic membrane assembly(GO:0097105)
3.5 17.5 GO:0001826 inner cell mass cell differentiation(GO:0001826)
3.5 159.7 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
3.1 9.4 GO:0003285 septum secundum development(GO:0003285)
2.8 11.3 GO:0097477 NMDA glutamate receptor clustering(GO:0097114) spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
2.8 8.3 GO:0031133 regulation of axon diameter(GO:0031133) positive regulation of adenosine receptor signaling pathway(GO:0060168)
2.7 22.0 GO:0046959 habituation(GO:0046959)
2.7 8.0 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
2.6 7.9 GO:0003358 noradrenergic neuron development(GO:0003358)
2.6 10.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
2.5 20.2 GO:0032790 ribosome disassembly(GO:0032790)
2.5 7.4 GO:0097359 UDP-glucosylation(GO:0097359)
2.3 32.8 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
2.3 16.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
2.3 9.1 GO:0051866 general adaptation syndrome(GO:0051866)
2.1 6.3 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
2.0 61.3 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
2.0 13.8 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
1.8 9.1 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
1.8 5.4 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
1.7 5.1 GO:0070253 somatostatin secretion(GO:0070253)
1.6 8.1 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
1.5 7.5 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
1.5 29.1 GO:0071420 cellular response to histamine(GO:0071420)
1.4 8.6 GO:0051012 microtubule sliding(GO:0051012)
1.4 11.1 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
1.2 13.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
1.2 3.5 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
1.1 5.7 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
1.1 5.5 GO:0007042 lysosomal lumen acidification(GO:0007042)
1.1 6.5 GO:0033133 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
1.0 4.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
1.0 15.0 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
1.0 9.9 GO:0045329 carnitine biosynthetic process(GO:0045329)
1.0 6.9 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
1.0 11.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.9 6.3 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.9 9.0 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.9 4.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.9 11.2 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.8 11.7 GO:0035878 nail development(GO:0035878)
0.8 2.5 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.8 2.4 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.7 8.9 GO:0019388 galactose catabolic process(GO:0019388)
0.7 12.0 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.7 4.6 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.6 30.1 GO:0097484 dendrite extension(GO:0097484)
0.6 22.8 GO:2000810 regulation of bicellular tight junction assembly(GO:2000810)
0.6 41.7 GO:0007602 phototransduction(GO:0007602)
0.6 10.6 GO:0010002 cardioblast differentiation(GO:0010002)
0.6 9.3 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.6 2.9 GO:1900238 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.6 8.0 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.6 3.4 GO:1902306 negative regulation of sodium ion transport(GO:0010766) negative regulation of sodium ion transmembrane transport(GO:1902306) negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.6 1.7 GO:0006566 threonine metabolic process(GO:0006566)
0.6 5.0 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.5 20.3 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.5 2.2 GO:1900154 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.5 8.3 GO:0042737 drug catabolic process(GO:0042737)
0.5 8.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.5 3.4 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.5 6.6 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.5 8.4 GO:0060134 prepulse inhibition(GO:0060134)
0.5 4.5 GO:0032264 IMP salvage(GO:0032264)
0.4 6.1 GO:0045475 locomotor rhythm(GO:0045475)
0.4 4.2 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.4 0.8 GO:0046066 dGDP metabolic process(GO:0046066)
0.4 3.4 GO:0021637 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.4 16.9 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.4 1.5 GO:0002331 pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.4 23.0 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.3 8.0 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.3 3.8 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.3 4.1 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.3 7.9 GO:0006525 arginine metabolic process(GO:0006525)
0.3 4.8 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.3 9.2 GO:0030199 collagen fibril organization(GO:0030199)
0.3 5.0 GO:0031053 primary miRNA processing(GO:0031053)
0.3 8.6 GO:0097352 autophagosome maturation(GO:0097352)
0.3 2.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.3 9.2 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.3 5.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.3 5.7 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.3 1.3 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.2 5.7 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.2 0.9 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.2 7.3 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.2 15.9 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.2 2.3 GO:0032494 response to peptidoglycan(GO:0032494)
0.2 4.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.2 13.8 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.2 4.9 GO:0030316 osteoclast differentiation(GO:0030316)
0.2 8.4 GO:0018149 peptide cross-linking(GO:0018149)
0.2 2.8 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.2 5.8 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.1 1.8 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of membrane repolarization during action potential(GO:0098903)
0.1 0.8 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 2.3 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 9.5 GO:0030574 collagen catabolic process(GO:0030574)
0.1 4.1 GO:0007160 cell-matrix adhesion(GO:0007160)
0.1 2.9 GO:0002507 tolerance induction(GO:0002507)
0.1 1.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 7.0 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 5.3 GO:0001657 ureteric bud development(GO:0001657) mesonephros development(GO:0001823) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164)
0.1 1.7 GO:0010952 positive regulation of peptidase activity(GO:0010952)
0.1 1.0 GO:0015889 cobalamin transport(GO:0015889)
0.1 7.1 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1 0.6 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 3.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 1.4 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.1 12.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 11.9 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 12.8 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 9.4 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.1 2.0 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 3.2 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 2.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 2.3 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 8.4 GO:0016197 endosomal transport(GO:0016197)
0.0 2.3 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 7.8 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 1.7 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 0.5 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 1.9 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 2.7 GO:0008652 cellular amino acid biosynthetic process(GO:0008652)
0.0 0.9 GO:0006936 muscle contraction(GO:0006936)
0.0 2.6 GO:0048705 skeletal system morphogenesis(GO:0048705)
0.0 3.3 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
31.4 156.9 GO:0098843 postsynaptic endocytic zone(GO:0098843)
11.8 82.9 GO:0044326 dendritic spine neck(GO:0044326)
10.7 42.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
7.1 49.5 GO:1990761 growth cone lamellipodium(GO:1990761)
3.6 43.5 GO:0043203 axon hillock(GO:0043203)
3.3 32.8 GO:0042587 glycogen granule(GO:0042587)
3.2 45.5 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
3.0 11.8 GO:0070876 SOSS complex(GO:0070876)
2.8 13.8 GO:0001652 granular component(GO:0001652)
2.3 72.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
2.0 8.0 GO:0032044 DSIF complex(GO:0032044)
1.5 9.1 GO:0032280 symmetric synapse(GO:0032280)
1.2 20.9 GO:0005687 U4 snRNP(GO:0005687)
1.2 8.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.9 16.1 GO:0033270 paranode region of axon(GO:0033270)
0.9 3.4 GO:0045160 myosin I complex(GO:0045160)
0.8 29.1 GO:1902711 GABA-A receptor complex(GO:1902711)
0.8 4.9 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.8 19.5 GO:0033268 node of Ranvier(GO:0033268)
0.7 11.1 GO:0000124 SAGA complex(GO:0000124)
0.7 4.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.6 12.4 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.6 5.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.5 44.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.5 8.8 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.4 51.6 GO:0005796 Golgi lumen(GO:0005796)
0.4 12.0 GO:0034451 centriolar satellite(GO:0034451)
0.4 20.6 GO:0005801 cis-Golgi network(GO:0005801)
0.3 3.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.3 23.1 GO:0005581 collagen trimer(GO:0005581)
0.3 18.6 GO:0031519 PcG protein complex(GO:0031519)
0.3 3.2 GO:0036038 MKS complex(GO:0036038)
0.3 11.7 GO:0008305 integrin complex(GO:0008305)
0.2 2.2 GO:0016013 syntrophin complex(GO:0016013)
0.2 8.6 GO:0000421 autophagosome membrane(GO:0000421)
0.2 5.4 GO:0005861 troponin complex(GO:0005861)
0.2 7.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.2 9.0 GO:0048786 presynaptic active zone(GO:0048786)
0.2 39.9 GO:0030426 growth cone(GO:0030426)
0.2 1.9 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.2 8.4 GO:0001533 cornified envelope(GO:0001533)
0.1 71.8 GO:0043025 neuronal cell body(GO:0043025)
0.1 5.1 GO:0043195 terminal bouton(GO:0043195)
0.1 1.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 10.1 GO:0060170 ciliary membrane(GO:0060170)
0.1 26.4 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 15.4 GO:0005923 bicellular tight junction(GO:0005923)
0.1 4.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 2.5 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 21.6 GO:0016324 apical plasma membrane(GO:0016324)
0.1 4.3 GO:0005811 lipid particle(GO:0005811)
0.1 14.9 GO:0045202 synapse(GO:0045202)
0.1 11.5 GO:0031901 early endosome membrane(GO:0031901)
0.1 17.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 8.5 GO:0098793 presynapse(GO:0098793)
0.1 16.8 GO:0005770 late endosome(GO:0005770)
0.1 22.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 7.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 4.6 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.5 GO:0031105 septin complex(GO:0031105)
0.0 6.3 GO:0031965 nuclear membrane(GO:0031965)
0.0 5.3 GO:0001726 ruffle(GO:0001726)
0.0 1.5 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 3.5 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 5.0 GO:0061695 transferase complex, transferring phosphorus-containing groups(GO:0061695)
0.0 6.5 GO:0005768 endosome(GO:0005768)
0.0 49.7 GO:0016021 integral component of membrane(GO:0016021)
0.0 0.4 GO:1902555 endoribonuclease complex(GO:1902555)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
14.5 72.4 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
13.7 41.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
13.1 156.9 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
7.1 42.9 GO:0030492 hemoglobin binding(GO:0030492)
6.6 19.9 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
5.9 82.9 GO:1990239 steroid hormone binding(GO:1990239)
5.8 29.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
5.6 11.3 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
4.4 13.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
4.1 57.9 GO:0048156 tau protein binding(GO:0048156)
3.1 9.3 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
2.5 10.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
2.5 7.4 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
2.1 6.4 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
2.1 6.3 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
2.0 8.0 GO:0016841 ammonia-lyase activity(GO:0016841)
1.9 9.5 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
1.7 18.8 GO:0019869 chloride channel inhibitor activity(GO:0019869)
1.6 7.9 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
1.6 57.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
1.5 21.3 GO:0042043 neurexin family protein binding(GO:0042043)
1.5 8.9 GO:0004614 phosphoglucomutase activity(GO:0004614)
1.3 6.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
1.3 16.9 GO:0015248 sterol transporter activity(GO:0015248)
1.3 3.8 GO:0008502 melatonin receptor activity(GO:0008502)
1.2 5.8 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
1.1 59.8 GO:0015485 cholesterol binding(GO:0015485)
1.1 5.4 GO:0034191 apolipoprotein receptor binding(GO:0034190) apolipoprotein A-I receptor binding(GO:0034191)
1.0 8.1 GO:0050816 phosphothreonine binding(GO:0050816)
1.0 5.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
1.0 15.4 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.9 8.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.9 11.7 GO:0038132 neuregulin binding(GO:0038132)
0.9 32.4 GO:0017091 AU-rich element binding(GO:0017091)
0.9 9.4 GO:0051525 NFAT protein binding(GO:0051525)
0.8 3.4 GO:0035276 ethanol binding(GO:0035276)
0.8 2.5 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.8 4.1 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.8 6.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.8 4.6 GO:0004882 androgen receptor activity(GO:0004882)
0.7 20.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.7 69.2 GO:0005518 collagen binding(GO:0005518)
0.7 6.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.6 13.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.5 3.2 GO:0008158 hedgehog receptor activity(GO:0008158)
0.5 5.4 GO:0031014 troponin T binding(GO:0031014)
0.5 55.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.5 4.6 GO:0051430 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.5 4.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.5 9.1 GO:0004707 MAP kinase activity(GO:0004707)
0.5 5.7 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.5 38.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.4 4.1 GO:0031433 telethonin binding(GO:0031433)
0.4 4.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.4 11.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.3 8.9 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.3 21.1 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.3 1.7 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.3 6.6 GO:0042171 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.3 15.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.3 2.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.3 8.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.3 17.5 GO:0030331 estrogen receptor binding(GO:0030331)
0.3 9.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.3 3.5 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.3 11.6 GO:0050699 WW domain binding(GO:0050699)
0.3 2.8 GO:0051425 PTB domain binding(GO:0051425)
0.3 5.8 GO:0050811 GABA receptor binding(GO:0050811)
0.3 28.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 4.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 15.6 GO:0016836 hydro-lyase activity(GO:0016836)
0.2 8.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 1.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 16.3 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.2 5.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 3.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 3.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 3.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 2.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2 19.5 GO:0043130 ubiquitin binding(GO:0043130)
0.2 1.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 8.3 GO:0043621 protein self-association(GO:0043621)
0.2 22.1 GO:0005262 calcium channel activity(GO:0005262)
0.2 2.9 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.2 10.8 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.2 2.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 5.1 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 9.7 GO:0016209 antioxidant activity(GO:0016209)
0.1 1.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 12.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 10.2 GO:0030165 PDZ domain binding(GO:0030165)
0.1 3.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 5.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 2.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 8.8 GO:0051015 actin filament binding(GO:0051015)
0.1 1.0 GO:0031419 cobalamin binding(GO:0031419)
0.1 2.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 13.4 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.1 7.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 1.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 1.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.2 GO:0005522 profilin binding(GO:0005522)
0.1 4.2 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 0.9 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 13.8 GO:0030246 carbohydrate binding(GO:0030246)
0.0 4.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 2.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 13.6 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 1.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 5.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 12.2 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 2.2 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 2.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 6.0 GO:0046982 protein heterodimerization activity(GO:0046982)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 156.9 PID NCADHERIN PATHWAY N-cadherin signaling events
1.2 68.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
1.0 72.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.8 18.9 PID S1P S1P1 PATHWAY S1P1 pathway
0.6 11.9 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.4 46.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.4 75.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3 11.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.3 11.7 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.3 9.1 ST GA12 PATHWAY G alpha 12 Pathway
0.3 11.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.3 11.2 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.3 7.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 9.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.2 14.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 31.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 3.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 2.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 8.2 PID AP1 PATHWAY AP-1 transcription factor network
0.1 21.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 2.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 2.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.8 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.7 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 156.9 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
2.3 86.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
1.5 82.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
1.1 20.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.9 29.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.8 75.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.6 17.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.6 15.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.6 9.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.5 9.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.4 7.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.3 10.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 5.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.3 4.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.3 13.2 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.3 56.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.3 7.9 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.2 10.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 8.0 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.2 16.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 10.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 20.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 9.7 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.2 11.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.2 13.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 5.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.2 3.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 4.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 2.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 7.1 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.2 6.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 15.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 21.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 15.4 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 2.0 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 2.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 3.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 0.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 6.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 0.4 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 3.6 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 14.5 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 2.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription