Motif ID: AHR_ARNT_ARNT2.p2

Z-value: 1.577


Transcription factors associated with AHR_ARNT_ARNT2.p2:

Gene SymbolEntrez IDGene Name
AHR 196 aryl hydrocarbon receptor
ARNT 405 aryl hydrocarbon receptor nuclear translocator
ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ARNT2chr15_+_78483624-0.533.5e-02Click!
AHRchr7_+_17304707-0.401.3e-01Click!
ARNTchr1_-_1491158350.107.1e-01Click!


Activity profile for motif AHR_ARNT_ARNT2.p2.

activity profile for motif AHR_ARNT_ARNT2.p2


Sorted Z-values histogram for motif AHR_ARNT_ARNT2.p2

Sorted Z-values for motif AHR_ARNT_ARNT2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AHR_ARNT_ARNT2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_19523526 2.959 NM_001127717
NM_198129
LAMA3

laminin, alpha 3

chr2_+_203208064 1.990 NM_173511
FAM117B
family with sequence similarity 117, member B
chr12_+_4253143 1.477 NM_001759
CCND2
cyclin D2
chr6_-_10520592 1.452 NM_001032280
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr16_+_22733307 1.251 NM_006043
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr8_+_126079929 1.019 SQLE
squalene epoxidase
chr15_+_38923914 1.017 NM_001032367
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr15_+_38923470 0.997 NM_003710
NM_181642
SPINT1

serine peptidase inhibitor, Kunitz type 1

chr1_-_6585268 0.988 KLHL21
kelch-like 21 (Drosophila)
chr10_-_103869923 0.976 NM_001113407
LDB1
LIM domain binding 1
chr1_-_43196911 0.965 SLC2A1
solute carrier family 2 (facilitated glucose transporter), member 1
chr1_-_58815415 0.942 TACSTD2
tumor-associated calcium signal transducer 2
chr15_-_35178888 0.939 NM_172316
MEIS2
Meis homeobox 2
chr15_+_81906983 0.896 NM_003027
SH3GL3
SH3-domain GRB2-like 3
chr7_-_91601613 0.852 CYP51A1
cytochrome P450, family 51, subfamily A, polypeptide 1
chrX_+_37429927 0.844 NM_021083
XK
X-linked Kx blood group (McLeod syndrome)
chr15_-_73719546 0.833 NM_018285
IMP3
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr8_+_126079900 0.832 NM_003129
SQLE
squalene epoxidase
chr15_-_66900266 0.822 ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr15_+_50098730 0.816 MAPK6
mitogen-activated protein kinase 6
chr3_+_195336625 0.814 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chrX_+_109132994 0.803 NM_032227
TMEM164
transmembrane protein 164
chr3_+_195336631 0.802 HES1
hairy and enhancer of split 1, (Drosophila)
chr15_+_50098724 0.780 MAPK6
mitogen-activated protein kinase 6
chr20_-_33335919 0.772 NM_181468
EIF6
eukaryotic translation initiation factor 6
chr15_-_61461127 0.772 NM_001218
NM_206925
CA12

carbonic anhydrase XII

chr7_-_91601711 0.769 CYP51A1
cytochrome P450, family 51, subfamily A, polypeptide 1
chr1_+_1396975 0.762 ATAD3B
ATPase family, AAA domain containing 3B
chr19_-_50601406 0.754 NM_001142502
PPP1R13L
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr1_+_1397021 0.728 NM_031921
ATAD3B
ATPase family, AAA domain containing 3B
chr8_+_126511739 0.723 NM_025195
TRIB1
tribbles homolog 1 (Drosophila)
chr20_+_20296744 0.722 NM_002196
INSM1
insulinoma-associated 1
chr19_-_614158 0.702 RNF126
ring finger protein 126
chr7_-_91601764 0.696 NM_000786
CYP51A1
cytochrome P450, family 51, subfamily A, polypeptide 1
chr15_-_61460967 0.682 CA12
carbonic anhydrase XII
chr20_-_33335703 0.678 EIF6
eukaryotic translation initiation factor 6
chr6_+_15353681 0.658 JARID2
jumonji, AT rich interactive domain 2
chr19_-_614155 0.655 RNF126
ring finger protein 126
chr12_-_44948800 0.648 SLC38A1
solute carrier family 38, member 1
chrX_+_152608159 0.635 NM_001142806
SLC6A8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr19_-_614219 0.621 NM_194460
RNF126
ring finger protein 126
chr8_+_31616809 0.610 NM_013962
NRG1
neuregulin 1
chr1_-_6585485 0.606 NM_014851
KLHL21
kelch-like 21 (Drosophila)
chrX_+_109132507 0.603 NM_017698
TMEM164
transmembrane protein 164
chr6_+_43592812 0.601 POLR1C
polymerase (RNA) I polypeptide C, 30kDa
chr6_+_125517033 0.591 NM_001003395
TPD52L1
tumor protein D52-like 1
chr16_+_22732982 0.589 HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr6_+_34312667 0.587 HMGA1
high mobility group AT-hook 1
chr15_+_50098700 0.576 NM_002748
MAPK6
mitogen-activated protein kinase 6
chr3_-_191321367 0.574 LEPREL1
leprecan-like 1
chr7_+_138695537 0.572 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr1_+_199519202 0.571 NM_000299
NM_001005337
PKP1

plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)

chr19_-_614195 0.571 RNF126
ring finger protein 126
chr22_+_20101661 0.565 NM_015094
HIC2
hypermethylated in cancer 2
chr19_-_51983024 0.556 SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr6_+_43592758 0.553 NM_004875
NM_203290
POLR1C

polymerase (RNA) I polypeptide C, 30kDa

chr15_+_99237527 0.548 NM_000693
ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr7_-_105712646 0.546 NM_005746
NAMPT
nicotinamide phosphoribosyltransferase
chr20_+_43468617 0.531 NM_001048223
NM_001048224
DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chrX_+_48265107 0.518 NM_006579
EBP
emopamil binding protein (sterol isomerase)
chr15_+_99237555 0.504 ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr15_-_35179185 0.498 MEIS2
Meis homeobox 2
chr6_+_43846735 0.495 VEGFA
vascular endothelial growth factor A
chr9_-_98841186 0.491 NM_001333
CTSL2
cathepsin L2
chr6_+_34312625 0.491 NM_145901
NM_145902
HMGA1

high mobility group AT-hook 1

chr10_-_104168890 0.489 NM_002779
PSD
pleckstrin and Sec7 domain containing
chr22_+_18485068 0.485 RANBP1
RAN binding protein 1
chr6_+_125516499 0.482 NM_001003396
NM_001003397
NM_003287
TPD52L1


tumor protein D52-like 1


chr17_+_77289804 0.481 SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr11_-_87548199 0.481 NM_022337
RAB38
RAB38, member RAS oncogene family
chr1_-_232681471 0.480 NM_005646
TARBP1
TAR (HIV-1) RNA binding protein 1
chrX_-_48661226 0.474 NM_006875
PIM2
pim-2 oncogene
chr9_-_102154915 0.468 NM_017746
TEX10
testis expressed 10
chr10_-_104168559 0.463 PSD
pleckstrin and Sec7 domain containing
chr7_+_99865340 0.456 MEPCE
methylphosphate capping enzyme
chrX_-_18282698 0.452 NM_006089
SCML2
sex comb on midleg-like 2 (Drosophila)
chr7_-_91601972 0.448 NM_001146152
CYP51A1
cytochrome P450, family 51, subfamily A, polypeptide 1
chr6_+_30402203 0.445


chr21_+_34367678 0.445 NM_032476
NM_006933
MRPS6
SLC5A3
mitochondrial ribosomal protein S6
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr4_-_83569476 0.445 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chrX_-_137621060 0.444 FGF13
fibroblast growth factor 13
chrX_-_138114846 0.439 NM_001139498
NM_001139500
NM_001139501
FGF13


fibroblast growth factor 13


chr1_+_1437400 0.437 ATAD3A
ATAD3B
ATPase family, AAA domain containing 3A
ATPase family, AAA domain containing 3B
chr11_-_114880275 0.437 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr1_-_54076521 0.435 TMEM48
transmembrane protein 48
chr5_-_134397470 0.433 PITX1
paired-like homeodomain 1
chr17_+_52517529 0.431 NM_003488
AKAP1
A kinase (PRKA) anchor protein 1
chr6_-_86409415 0.430 SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr10_+_21863099 0.429 NM_001195627
NM_001195628
NM_001195630
NM_004641
MLLT10



myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10



chr16_+_31098962 0.429 FUS
fused in sarcoma
chr17_+_15789147 0.429 ADORA2B
adenosine A2b receptor
chr6_-_10523424 0.426 NM_003220
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr9_+_4975082 0.420 JAK2
Janus kinase 2
chrX_-_109447970 0.418 NM_001025580
NM_015365
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr7_+_138695241 0.416 LUC7L2
LUC7-like 2 (S. cerevisiae)
chrX_-_137621492 0.414 NM_004114
FGF13
fibroblast growth factor 13
chr6_+_135544170 0.413 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr3_+_25806552 0.413 NM_001145391
NM_017897
OXSM

3-oxoacyl-ACP synthase, mitochondrial

chr17_+_34114924 0.412 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr1_-_54076695 0.411 NM_001168551
NM_018087
TMEM48

transmembrane protein 48

chr1_-_38046433 0.410 YRDC
yrdC domain containing (E. coli)
chr22_+_19601721 0.409 CRKL
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr6_+_34312641 0.409 HMGA1
high mobility group AT-hook 1
chr17_+_77582774 0.407 NM_005052
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chrX_+_153644300 0.407 DKC1
dyskeratosis congenita 1, dyskerin
chr1_+_1437734 0.403 NM_001170536
ATAD3A
ATPase family, AAA domain containing 3A
chr6_+_135544214 0.403 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr6_+_135544138 0.401 NM_001130172
NM_001130173
NM_001161656
NM_001161657
NM_001161658
NM_001161659
NM_001161660
NM_005375
MYB







v-myb myeloblastosis viral oncogene homolog (avian)







chr17_-_37328755 0.400 ACLY
ATP citrate lyase
chr12_-_31370305 0.400 FAM60A
family with sequence similarity 60, member A
chr20_-_33335985 0.400 NM_002212
NM_181466
EIF6

eukaryotic translation initiation factor 6

chr5_+_154115046 0.397 LARP1
La ribonucleoprotein domain family, member 1
chr17_+_69939806 0.395 GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr12_-_74710741 0.394 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr1_-_38046439 0.394 NM_024640
YRDC
yrdC domain containing (E. coli)
chrX_-_109447954 0.393 AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr15_-_66900143 0.393 ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr22_+_18485057 0.390 RANBP1
RAN binding protein 1
chr20_+_43468046 0.390 NM_001197139
NM_001048221
NM_001048222
NM_001197140
NM_018478
DBNDD2




dysbindin (dystrobrevin binding protein 1) domain containing 2




chr7_+_138695236 0.390 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr17_-_37328679 0.388 ACLY
ATP citrate lyase
chr2_+_219283751 0.387 NM_014640
TTLL4
tubulin tyrosine ligase-like family, member 4
chr16_+_31098963 0.386 FUS
fused in sarcoma
chr17_+_69939130 0.386 NM_022036
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr6_+_34312633 0.385 HMGA1
high mobility group AT-hook 1
chr19_+_1358750 0.383 DAZAP1
DAZ associated protein 1
chr7_-_95789204 0.383 NM_001160210
NM_014251
SLC25A13

solute carrier family 25, member 13 (citrin)

chr19_+_43447262 0.382 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr14_+_100262916 0.378 DLK1
delta-like 1 homolog (Drosophila)
chr2_+_28971007 0.378 NM_015131
WDR43
WD repeat domain 43
chr1_-_165789640 0.377 NM_003851
CREG1
cellular repressor of E1A-stimulated genes 1
chr5_-_176763991 0.377 F12
coagulation factor XII (Hageman factor)
chr7_+_138695209 0.377 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr4_+_4439705 0.375 D4S234E
DNA segment on chromosome 4 (unique) 234 expressed sequence
chr6_-_86409283 0.375 NM_001159674
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr4_-_185984045 0.374 ACSL1
acyl-CoA synthetase long-chain family member 1
chr1_+_35019376 0.373 NM_024009
GJB3
gap junction protein, beta 3, 31kDa
chrX_+_130984912 0.372 NM_001042453
NM_016542
MST4

serine/threonine protein kinase MST4

chr17_-_77649393 0.371 NM_004104
FASN
fatty acid synthase
chr5_+_6686499 0.369 NM_001047
SRD5A1
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
chr19_+_50663089 0.369 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr12_-_31370351 0.369 FAM60A
family with sequence similarity 60, member A
chr1_-_165789586 0.369 CREG1
cellular repressor of E1A-stimulated genes 1
chr1_-_53566171 0.367 NM_001018054
NM_004631
NM_017522
LRP8


low density lipoprotein receptor-related protein 8, apolipoprotein e receptor


chr12_-_31370387 0.367 NM_001135811
NM_021238
NM_001135812
FAM60A


family with sequence similarity 60, member A


chr19_+_50601306 0.367 NM_012099
CD3EAP
CD3e molecule, epsilon associated protein
chr5_-_134942867 0.366 NM_004887
CXCL14
chemokine (C-X-C motif) ligand 14
chr17_+_15788955 0.366 NM_000676
ADORA2B
adenosine A2b receptor
chr22_+_19601723 0.362 CRKL
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr1_-_38046270 0.360 YRDC
yrdC domain containing (E. coli)
chr5_+_6686531 0.360 SRD5A1
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
chr1_-_165789630 0.359 CREG1
cellular repressor of E1A-stimulated genes 1
chr10_-_105442868 0.357 SH3PXD2A
SH3 and PX domains 2A
chr4_-_56996400 0.356 NM_002703
PPAT
phosphoribosyl pyrophosphate amidotransferase
chr17_-_37328716 0.355 ACLY
ATP citrate lyase
chr1_+_54184595 0.352 NM_052940
LRRC42
leucine rich repeat containing 42
chr1_-_38046410 0.352 YRDC
yrdC domain containing (E. coli)
chr17_-_37328764 0.351 NM_001096
NM_198830
ACLY

ATP citrate lyase

chr10_+_21863272 0.350 MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr16_+_15397120 0.350 MPV17L
MPV17 mitochondrial membrane protein-like
chr4_-_39655554 0.347 PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr7_+_16759845 0.347 NM_014399
TSPAN13
tetraspanin 13
chr2_+_169021039 0.347 NM_203463
LASS6
LAG1 homolog, ceramide synthase 6
chr20_-_10602139 0.346 JAG1
jagged 1
chr8_+_102574012 0.344 GRHL2
grainyhead-like 2 (Drosophila)
chr7_+_99865189 0.343 NM_019606
MEPCE
methylphosphate capping enzyme
chr7_-_105712565 0.343 NAMPT
nicotinamide phosphoribosyltransferase
chr7_+_154720547 0.343 INSIG1
insulin induced gene 1
chr17_-_44058612 0.342 NM_024017
HOXB9
homeobox B9
chr6_-_119712596 0.341 NM_005907
MAN1A1
mannosidase, alpha, class 1A, member 1
chr7_+_138695144 0.341 NM_016019
LUC7L2
LUC7-like 2 (S. cerevisiae)
chr12_-_119116848 0.339 NM_006836
GCN1L1
GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
chrX_+_19271931 0.337 NM_000284
NM_001173454
NM_001173455
NM_001173456
PDHA1



pyruvate dehydrogenase (lipoamide) alpha 1



chr7_+_2360954 0.336 NM_001037283
NM_003751
EIF3B

eukaryotic translation initiation factor 3, subunit B

chr5_+_49998528 0.336 NM_001178056
NM_024615
PARP8

poly (ADP-ribose) polymerase family, member 8

chr1_+_1437358 0.334 NM_001170535
NM_018188
ATAD3A

ATPase family, AAA domain containing 3A

chr17_+_77289704 0.331 SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chrX_+_153644210 0.331 NM_001142463
NM_001363
DKC1

dyskeratosis congenita 1, dyskerin

chr4_-_76817582 0.330 G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr8_+_110621092 0.330 NM_198120
EBAG9
estrogen receptor binding site associated, antigen, 9
chr7_+_115637795 0.329 NM_015641
TES
testis derived transcript (3 LIM domains)
chr7_+_2361051 0.327 EIF3B
eukaryotic translation initiation factor 3, subunit B
chr11_-_78829342 0.327 NM_001098816
ODZ4
odz, odd Oz/ten-m homolog 4 (Drosophila)
chr4_-_76817587 0.325 G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr7_+_2361024 0.324 EIF3B
eukaryotic translation initiation factor 3, subunit B
chr20_-_10602429 0.324 NM_000214
JAG1
jagged 1
chr9_-_99994704 0.324 NM_052820
CORO2A
coronin, actin binding protein, 2A
chr16_+_23754822 0.324 PRKCB
protein kinase C, beta
chr16_+_15397087 0.323 NM_001128423
NM_173803
MPV17L

MPV17 mitochondrial membrane protein-like

chr4_+_38341982 0.323 NM_016531
KLF3
Kruppel-like factor 3 (basic)
chr2_+_181553783 0.322 UBE2E3
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr8_+_110621485 0.321 NM_004215
EBAG9
estrogen receptor binding site associated, antigen, 9
chr6_-_86409354 0.321 NM_001159673
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr17_-_38081604 0.321 PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr1_+_219119623 0.319 HLX
H2.0-like homeobox
chr22_-_19685998 0.318 THAP7
THAP domain containing 7
chr16_+_31098971 0.318 FUS
fused in sarcoma
chr1_+_65386559 0.318 AK4
adenylate kinase 4
chr3_-_52065130 0.317 NM_001947
DUSP7
dual specificity phosphatase 7
chr22_+_18485076 0.317 RANBP1
RAN binding protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.31 1.74e-15 GO:0044260 cellular macromolecule metabolic process
1.52 2.70e-14 GO:0010467 gene expression
1.23 3.59e-14 GO:0044237 cellular metabolic process
1.43 5.94e-12 GO:0090304 nucleic acid metabolic process
1.37 4.39e-11 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.48 5.75e-11 GO:0016070 RNA metabolic process
1.24 1.75e-10 GO:0043170 macromolecule metabolic process
1.18 2.13e-10 GO:0008152 metabolic process
1.32 3.03e-10 GO:0034641 cellular nitrogen compound metabolic process
1.19 8.56e-10 GO:0044238 primary metabolic process
1.31 1.53e-09 GO:0060255 regulation of macromolecule metabolic process
1.31 1.64e-09 GO:0006807 nitrogen compound metabolic process
1.36 1.48e-08 GO:0010468 regulation of gene expression
1.58 1.15e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.36 2.24e-07 GO:0051252 regulation of RNA metabolic process
1.27 2.70e-07 GO:0031323 regulation of cellular metabolic process
1.25 5.96e-07 GO:0019222 regulation of metabolic process
1.34 6.59e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.33 7.75e-07 GO:0010556 regulation of macromolecule biosynthetic process
1.26 2.92e-06 GO:0080090 regulation of primary metabolic process
1.68 3.53e-06 GO:0051276 chromosome organization
1.30 3.69e-06 GO:0009889 regulation of biosynthetic process
1.30 3.78e-06 GO:0031326 regulation of cellular biosynthetic process
1.64 4.36e-06 GO:0010628 positive regulation of gene expression
1.29 1.06e-05 GO:0009058 biosynthetic process
1.34 1.14e-05 GO:0006355 regulation of transcription, DNA-dependent
1.08 1.60e-05 GO:0009987 cellular process
1.30 1.67e-05 GO:0044249 cellular biosynthetic process
1.45 2.08e-05 GO:0010604 positive regulation of macromolecule metabolic process
1.61 2.39e-05 GO:0051254 positive regulation of RNA metabolic process
1.64 2.65e-05 GO:0045893 positive regulation of transcription, DNA-dependent
1.43 2.66e-05 GO:0009893 positive regulation of metabolic process
1.62 3.35e-05 GO:0006396 RNA processing
1.36 3.54e-05 GO:0034645 cellular macromolecule biosynthetic process
1.51 4.64e-05 GO:0006351 transcription, DNA-dependent
1.35 8.24e-05 GO:0009059 macromolecule biosynthetic process
1.81 1.09e-04 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.27 1.40e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.53 2.54e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
2.31 3.09e-04 GO:0045165 cell fate commitment
1.40 3.77e-04 GO:0031325 positive regulation of cellular metabolic process
1.55 4.80e-04 GO:0045595 regulation of cell differentiation
1.67 5.78e-04 GO:0006325 chromatin organization
1.25 9.84e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.50 1.10e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.67 1.15e-03 GO:0032583 regulation of gene-specific transcription
1.61 1.53e-03 GO:0019226 transmission of nerve impulse
1.61 1.53e-03 GO:0035637 multicellular organismal signaling
1.48 1.62e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.45 2.16e-03 GO:0009891 positive regulation of biosynthetic process
1.43 3.18e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.45 3.20e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.57 4.28e-03 GO:0051253 negative regulation of RNA metabolic process
1.57 4.47e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.41 4.68e-03 GO:0009892 negative regulation of metabolic process
1.54 5.02e-03 GO:0010629 negative regulation of gene expression
1.31 5.14e-03 GO:0006996 organelle organization
1.52 5.72e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.61 6.12e-03 GO:0007268 synaptic transmission
1.39 8.23e-03 GO:0032774 RNA biosynthetic process
1.68 8.88e-03 GO:0016568 chromatin modification
1.23 9.40e-03 GO:0044267 cellular protein metabolic process
1.40 1.14e-02 GO:0050793 regulation of developmental process
1.50 1.18e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.41 1.30e-02 GO:0031324 negative regulation of cellular metabolic process
1.50 1.35e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.47 1.51e-02 GO:0009890 negative regulation of biosynthetic process
1.22 1.65e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.48 1.76e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
2.51 1.78e-02 GO:0048638 regulation of developmental growth
1.46 2.24e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.62 2.50e-02 GO:0006397 mRNA processing
1.77 2.66e-02 GO:0045596 negative regulation of cell differentiation
1.21 3.45e-02 GO:0071842 cellular component organization at cellular level
2.20 3.49e-02 GO:0006399 tRNA metabolic process
1.75 3.63e-02 GO:0034660 ncRNA metabolic process
1.55 4.12e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.88 4.49e-02 GO:0016569 covalent chromatin modification

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.33 5.70e-25 GO:0005634 nucleus
1.19 2.73e-20 GO:0043231 intracellular membrane-bounded organelle
1.19 5.33e-20 GO:0043227 membrane-bounded organelle
1.13 2.75e-18 GO:0005622 intracellular
1.13 1.63e-17 GO:0044424 intracellular part
1.49 5.53e-17 GO:0044428 nuclear part
1.53 3.03e-16 GO:0031981 nuclear lumen
1.47 3.71e-16 GO:0070013 intracellular organelle lumen
1.45 9.74e-16 GO:0031974 membrane-enclosed lumen
1.45 4.84e-15 GO:0043233 organelle lumen
1.15 5.38e-15 GO:0043229 intracellular organelle
1.61 8.22e-15 GO:0005654 nucleoplasm
1.15 9.80e-15 GO:0043226 organelle
1.19 3.40e-08 GO:0044446 intracellular organelle part
1.64 6.92e-08 GO:0044451 nucleoplasm part
1.19 1.11e-07 GO:0044422 organelle part
1.24 1.56e-06 GO:0032991 macromolecular complex
1.04 3.86e-04 GO:0044464 cell part
1.04 4.08e-04 GO:0005623 cell
1.82 1.33e-03 GO:0000785 chromatin
4.22 2.95e-03 GO:0031519 PcG protein complex
1.20 4.72e-03 GO:0043234 protein complex
1.52 5.97e-03 GO:0030529 ribonucleoprotein complex
1.74 7.34e-03 GO:0005667 transcription factor complex
1.47 1.05e-02 GO:0005694 chromosome
2.64 1.57e-02 GO:0034708 methyltransferase complex
2.64 1.57e-02 GO:0035097 histone methyltransferase complex
1.28 4.80e-02 GO:0005739 mitochondrion

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.37 9.71e-14 GO:0003676 nucleic acid binding
1.65 5.24e-11 GO:0030528 transcription regulator activity
1.55 2.20e-07 GO:0001071 nucleic acid binding transcription factor activity
1.55 2.20e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.59 2.29e-07 GO:0003723 RNA binding
1.33 2.63e-07 GO:0000166 nucleotide binding
1.32 3.18e-06 GO:0003677 DNA binding
1.13 6.45e-06 GO:0005515 protein binding
1.58 2.58e-05 GO:0043565 sequence-specific DNA binding
1.80 1.13e-04 GO:0016563 transcription activator activity
1.07 1.56e-04 GO:0005488 binding
1.67 5.63e-04 GO:0000988 protein binding transcription factor activity
1.67 5.63e-04 GO:0000989 transcription factor binding transcription factor activity
1.33 7.70e-04 GO:0005524 ATP binding
1.66 9.65e-04 GO:0003712 transcription cofactor activity
1.32 1.20e-03 GO:0032559 adenyl ribonucleotide binding
1.32 1.22e-03 GO:0030554 adenyl nucleotide binding
1.28 1.28e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.27 2.83e-03 GO:0032553 ribonucleotide binding
1.27 2.83e-03 GO:0032555 purine ribonucleotide binding
1.27 3.20e-03 GO:0017076 purine nucleotide binding
1.38 7.43e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.68 8.57e-03 GO:0016564 transcription repressor activity
1.89 2.93e-02 GO:0003714 transcription corepressor activity
1.25 3.35e-02 GO:0016740 transferase activity