Mean activities

Top 10 and bottom 10 mean activities.

 Mean activities

Mean activities sorted by motif Z-value.

 Mean activities

Sorted mean activities for every motif.
Motif nameMean activityZ-ValueAssociated genesLogo
GZF1.p2 2.219 1.607 GZF1 (dJ322G13.2, ZBTB23)
XBP1.p3 0.986 2.701 XBP1
RXRG_dimer.p3 0.659 1.376 NR1H2 (NER, NER-I, RIP15, LXR-b)
RXRA (NR2B1)
PPARG (PPARG1, PPARG2, NR1C3, PPARgamma)
PPARA (hPPAR, NR1C1)
RXRB (NR2B2, H-2RIIBP, RCoR-1)
RXRG (NR2B3)
NKX2-2,8.p2 0.548 1.841 NKX2-2 (NKX2.2)
NKX2-8 (NKX2.8, Nkx2-9)
BACH2.p2 0.524 1.401 BACH2
TP53.p2 0.401 1.294 TP53 (p53, LFS1)
CEBPA,B_DDIT3.p2 0.387 0.702 DDIT3 (CHOP10, GADD153, CHOP)
CEBPA (C/EBP-alpha)
CEBPB (LAP, CRP2, NFIL6, IL6DBP)
ESRRA.p2 0.357 1.444 ESRRA (ERR1, ERRalpha, NR3B1, ERRa)
YY1.p2 0.314 5.925 YY1 (NF-E1, DELTA, UCRBP, YIN-YANG-1, INO80S)
EHF.p2 0.301 2.676 EHF
NRF1.p2 0.299 4.577 NRF1 (EWG, ALPHA-PAL)
ATF4.p2 0.293 1.521 ATF4 (TAXREB67, CREB-2)
ELK1,4_GABP{A,B1}.p3 0.290 3.358 GABPA (E4TF1A, NFT2, NRF2, E4TF1-60, NRF2A)
GABPB1 (E4TF1-47, GABPB)
ELK4 (SAP1)
ELK1
NFE2L2.p2 0.287 0.785 NFE2L2 (NRF2)
HIF1A.p2 0.287 2.107 HIF1A (MOP1, HIF-1alpha, PASD8, HIF1)
PBX1.p2 0.277 0.809 PBX1
MYB.p2 0.269 2.007 MYB (c-myb)
CREB1.p2 0.243 1.386 CREB1
TAL1_TCF{3,4,12}.p2 0.221 0.324 TCF3 (E2A, ITF1, MGC129647, MGC129648, bHLHb21)
TCF4 (SEF2-1B, ITF2, bHLHb19)
TAL1 (SCL, bHLHa17)
TCF12 (HEB, HTF4, HsT17266, bHLHb20)
ZNF143.p2 0.219 2.312 ZNF143 (SBF, pHZ-1, STAF)
NFY{A,B,C}.p2 0.198 2.051 NFYC (CBF-C)
NFYB (CBF-A, HAP3)
NFYA (HAP2, CBF-B)
TBP.p2 0.197 0.707 TBP (TFIID)
FOXQ1.p2 0.192 0.761 FOXQ1 (HFH1)
CTCF.p2 0.185 0.832 CTCF
EOMES.p2 0.176 0.523 EOMES (TBR2)
PAX4.p2 0.157 0.531 PAX4
HES1.p2 0.154 1.602 HES1 (FLJ20408, HES-1, Hes1, bHLHb39)
CUX2.p2 0.153 0.170 CUX2 (KIAA0293, CDP2)
E2F1..5.p2 0.149 0.879 E2F4 (E2F-4)
E2F5
E2F2 (E2F-2)
E2F1 (RBP3)
E2F3
SOX17.p2 0.146 0.948 SOX17
NKX3-1.p2 0.134 0.376 NKX3-1 (NKX3.1, BAPX2)
ATF5_CREB3.p2 0.125 0.896 ATF5
CREB3 (LZIP, Luman)
ZNF384.p2 0.119 0.880 ZNF384 (CAGH1A, CIZ, NMP4, NP)
TFEB.p2 0.116 0.686 TFEB
ELF1,2,4.p2 0.110 1.536 ELF2 (EU32, NERF, NERF-2, NERF-1A, NERF-1B)
ELF1
ELF4 (MEF, ELFR)
ARID5B.p2 0.108 0.188 ARID5B (FLJ21150, MRF2)
HOX{A4,D4}.p2 0.108 0.520 HOXA4
HOXD4
FOX{D1,D2}.p2 0.103 0.408 FOXD2 (FREAC9)
FOXD1 (FREAC4)
NFIX.p2 0.094 0.341 NFIX (NF1A)
PITX1..3.p2 0.080 0.747 PITX2 (IGDS, RS, Brx1, Otlx2, ARP1)
PITX3
PITX1 (PTX1, POTX)
bHLH_family.p2 0.078 0.713 ARNTL (MOP3, JAP3, BMAL1, PASD3, bHLHe5)
MITF (WS2A, MI, bHLHe32)
MXI1 (MXD2, MAD2, MXI, bHLHc11)
TFE3 (TFEA, bHLHe33)
CLOCK (KIAA0334, KAT13D, bHLHe8)
OLIG2 (RACK17, OLIGO2, bHLHe19)
MXD4 (MAD4, MSTP149, MST149, bHLHc12)
HEY2 (bHLHb32)
HEY1 (HESR-1, CHF2, HESR1, HRT-1, CHF-2, HERP2, BHLHb31)
HEYL (bHLHb33)
MLXIPL (WS-bHLH, MIO, CHREBP, MONDOB)
HES6 (bHLHc23)
MXD3 (MAD3, bHLHc13)
ARNTL2 (BMAL2, MOP9, CLIF, PASD9, bHLHe6)
ID1 (dJ857M17.1.2, bHLHb24)
MNT (ROX, MXD6, MAD6, bHLHd3)
OLIG1 (BHLHB6, bHLHe21)
NPAS2 (MOP4, PASD4, bHLHe9)
ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2 0.075 0.407 ARNT (HIF-1beta, bHLHe2)
MAX (bHLHd4)
MYC (c-Myc, bHLHe39)
USF1 (UEF, MLTFI, bHLHb11)
BHLHB2 (DEC1, bHLHe40)
ARNT2 (KIAA0307, bHLHe1)
NKX6-1,2.p2 0.070 0.236 NKX6-1 (Nkx6.1)
NKX6-2 (NKX6B, GTX, NKX6.1)
SPIB.p2 0.067 0.945 SPIB (SPI-B)
MAFB.p2 0.063 0.939 MAFB
PRDM1.p3 0.058 0.125 PRDM1 (PRDI-BF1)
ZNF148.p2 0.057 0.771 ZNF148 (BERF-1, ZBP-89, BFCOL1, HT-BETA, ZFP148, pHZ-52)
FOXN1.p2 0.053 0.239 FOXN1 (FKHL20)
BPTF.p2 0.053 0.774 BPTF (FAC1, NURF301)
SOX2.p2 0.052 0.317 SOX2
FOXD3.p2 0.051 0.441 FOXD3 (Genesis, HFH2)
TFAP4.p2 0.048 0.383 TFAP4 (AP-4)
KLF4.p3 0.045 1.260 KLF4 (EZF, GKLF)
PAX5.p2 0.045 1.068 PAX5 (BSAP)
HBP1_HMGB_SSRP1_UBTF.p2 0.043 0.258 HMGB2
HMGB3 (HMG2A, MGC90319)
SSRP1 (FACT80)
UBTF (UBF, NOR-90)
HBP1
RXR{A,B,G}.p2 0.042 0.343 RXRA (NR2B1)
RXRB (NR2B2, H-2RIIBP, RCoR-1)
RXRG (NR2B3)
TEAD1.p2 0.040 0.140 TEAD1 (TEF-1)
TEAD2 (ETF, TEF4, TEF-4, TEAD-2)
TEAD3 (TEF5, TEAD5, TEF-5, DTEF-1, ETFR-1, TEAD-3)
TEAD4 (TEF3, RTEF1, TEF-3, EFTR-2, TEFR-1, TCF13L1, hRTEF-1B)
PRRX1,2.p2 0.039 0.496 PRRX2 (PRX2, PMX2)
PRRX1 (PHOX1)
TFDP1.p2 0.036 1.267 TFDP1 (Dp-1, DRTF1, DP1)
ATF6.p2 0.028 0.158 ATF6 (ATF6A)
IKZF1.p2 0.025 0.125 IKZF1 (hIk-1, LyF-1, Hs.54452, IKAROS)
SP1.p2 0.024 0.782 SP1
NKX3-2.p2 0.024 0.179 NKX3-2 (NKX3B, NKX3.2)
GFI1.p2 0.022 0.172 GFI1
NHLH1,2.p2 0.022 0.309 NHLH1 (NSCL, NSCL1, bHLHa35)
NHLH2 (NSCL2, bHLHa34)
FOX{I1,J2}.p2 0.020 0.137 FOXI1 (FREAC6)
FOXJ2 (FHX)
SREBF1,2.p2 0.020 0.083 SREBF1 (SREBP1, bHLHd1)
SREBF2 (SREBP2, bHLHd2)
PAX2.p2 0.015 0.120 PAX2
POU3F1..4.p2 0.009 0.021 POU3F1 (OCT6, SCIP)
POU3F3 (BRN1, OTF8)
POU3F2 (POUF3, BRN2, OCT7)
POU3F4 (BRN4, OTF9)
MYBL2.p2 0.008 0.022 MYBL2 (BMYB, B-MYB)
TFAP2B.p2 0.007 0.204 TFAP2B (AP2-B)
ZBTB6.p2 0.003 0.025 ZBTB6 (ZID)
HOX{A6,A7,B6,B7}.p2 0.001 0.009 HOXB6
HOXA7
HOXB7
HOXA6
NFE2L1.p2 -0.001 -0.016 NFE2L1 (NRF1, LCR-F1, FLJ00380, TCF11)
NFKB1_REL_RELA.p2 -0.002 -0.011 RELA (p65)
REL (I-Rel)
NFKB1 (KBF1, p105)
MZF1.p2 -0.004 -0.112 MZF1 (MZF1B, ZSCAN6, MZF-1, Zfp98)
IKZF2.p2 -0.005 -0.033 IKZF2 (Helios)
NFATC1..3.p2 -0.007 -0.047 NFATC3 (NFAT4, NFATX)
NFATC2 (NF-ATP, NFATp, NFAT1)
NFATC1 (NF-ATC, NFATc, NFAT2)
EGR1..3.p2 -0.008 -0.141 EGR3 (PILOT)
EGR1 (TIS8, G0S30, NGFI-A, KROX-24, ZIF-268, AT225, ZNF225)
EGR2
IRF1,2,7.p3 -0.009 -0.037 IRF1 (MAR, IRF-1)
IRF2 (IRF-2, DKFZp686F0244)
IRF7 (IRF7A, IRF-7H)
LHX3,4.p2 -0.013 -0.043 LHX3
LHX4 (Gsh4)
HMGA1,2.p2 -0.017 -0.129 HMGA1
HMGA2 (BABL, LIPO)
ADNP_IRX_SIX_ZHX.p2 -0.021 -0.115 SIX5
ZHX1
IRX4
ADNP (KIAA0784, ADNP1)
ZHX3 (KIAA0395)
ZHX2 (KIAA0854)
IRX5 (IRX-2a)
SIX2
NR6A1.p2 -0.022 -0.029 NR6A1 (GCNF1, RTR)
SPI1.p2 -0.022 -0.386 SPI1 (PU.1, SPI-A, OF, SFPI1, SPI-1)
RBPJ.p2 -0.024 -0.098 RBPJ (SUH, IGKJRB, RBPJK, KBF2, RBP-J, CBF1)
ETS1,2.p2 -0.025 -0.228 ETS2
ETS1 (FLJ10768, ETS-1)
NFIL3.p2 -0.027 -0.054 NFIL3 (E4BP4, NFIL3A, NF-IL3A)
NFE2.p2 -0.028 -0.085 NFE2 (NF-E2)
PATZ1.p2 -0.030 -0.831 PATZ1 (MAZR, dJ400N23, ZBTB19, ZSG, RIAZ, PATZ)
AHR_ARNT_ARNT2.p2 -0.031 -0.380 ARNT (HIF-1beta, bHLHe2)
AHR
ARNT2 (KIAA0307, bHLHe1)
TLX2.p2 -0.031 -0.184 TLX2 (Enx, Tlx2, NCX)
TFAP2{A,C}.p2 -0.032 -1.311 TFAP2C (AP2-GAMMA, ERF1, TFAP2G, hAP-2g)
TFAP2A (AP-2)
ZFP161.p2 -0.040 -0.674 ZFP161 (ZNF478, ZBTB14)
ALX1.p2 -0.040 -0.117 ALX1
SRF.p3 -0.040 -0.092 SRF (MCM1)
ONECUT1,2.p2 -0.040 -0.130 ONECUT2 (OC-2)
ONECUT1 (HNF-6)
MAZ.p2 -0.041 -1.219 MAZ (ZF87, Pur-1, Zif87, ZNF801)
CDX1,2,4.p2 -0.042 -0.271 CDX1
CDX2
CDX4
GTF2I.p2 -0.043 -1.000 GTF2I (TFII-I, BAP-135, SPIN, BTKAP1, DIWS, IB291)
ZBTB16.p2 -0.044 -0.257 ZBTB16 (PLZF)
LMO2.p2 -0.045 -0.380 LMO2 (TTG2, RHOM2, RBTN2)
SOX5.p2 -0.047 -0.218 SOX5 (L-SOX5, MGC35153)
CRX.p2 -0.047 -0.194 CRX (CRD, LCA7, OTX3)
SPZ1.p2 -0.053 -0.603 SPZ1 (NYD-TSP1, FLJ25709)
ATF2.p2 -0.054 -0.240 ATF2 (TREB7, CRE-BP1, HB16)
NR5A1,2.p2 -0.055 -0.398 NR5A1 (FTZ1, SF-1, ELP, AD4BP)
NR5A2 (FTZ-F1beta, hB1F, LRH-1, FTZ-F1, hB1F-2, B1F2)
HIC1.p2 -0.059 -1.267 HIC1 (ZBTB29)
HSF1,2.p2 -0.063 -0.349 HSF1 (HSTF1)
HSF2
MTF1.p2 -0.064 -0.990 MTF1
FOS_FOS{B,L1}_JUN{B,D}.p2 -0.064 -0.271 FOS (c-fos, AP-1)
JUNB
FOSL1 (fra-1)
JUND (AP-1)
FOSB (G0S3, GOSB, GOS3, AP-1, MGC42291, DKFZp686C0818)
SOX{8,9,10}.p2 -0.068 -0.361 SOX9 (SRA1)
SOX8
SOX10 (DOM, WS4, WS2E)
SNAI1..3.p2 -0.068 -0.863 SNAI2 (SLUGH1)
SNAI1 (SNA, SLUGH2, SNAH)
SNAI3 (SMUC, Zfp293)
ZEB1.p2 -0.070 -0.694 ZEB1 (BZP, ZEB, AREB6, NIL-2-A, Zfhep, Zfhx1a)
FOXO1,3,4.p2 -0.077 -0.353 FOXO1 (FKH1)
FOXO4 (AFX1)
FOXO3 (AF6q21, FOXO2)
EP300.p2 -0.079 -0.749 EP300 (p300, KAT3B)
GATA1..3.p2 -0.092 -1.180 GATA1 (ERYF1, NFE1)
GATA2 (NFE1B)
GATA3 (HDR)
VSX1,2.p2 -0.093 -0.087 VSX2 (RET1)
VSX1 (PPD)
KLF12.p2 -0.094 -1.163 KLF12 (AP-2rep, HSPC122, AP2REP)
HOXA9_MEIS1.p2 -0.095 -0.124 MEIS1
HOXA9
ZIC1..3.p2 -0.097 -0.604 ZIC1 (ZIC, ZNF201)
ZIC2 (HPE5)
ZIC3 (HTX, ZNF203)
TFCP2.p2 -0.099 -1.162 TFCP2 (CP2, LSF, LBP-1C, TFCP2C)
SRY.p2 -0.103 -0.609 SRY (TDF)
RREB1.p2 -0.110 -2.016 RREB1 (HNT)
DBP.p2 -0.117 -0.696 DBP (DABP)
STAT2,4,6.p2 -0.118 -0.963 STAT2 (STAT113)
STAT4
STAT6 (D12S1644, IL-4-STAT)
CDC5L.p2 -0.125 -0.338 CDC5L (PCDC5RP, hCDC5, CEF1)
MEF2{A,B,C,D}.p2 -0.135 -0.663 MEF2A (RSRFC4, RSRFC9)
MEF2C
MEF2D
MEF2BNB-MEF2B (MEF2B, LOC729991-MEF2B)
MEF2B (RSRFR2, FLJ32648)
FEV.p2 -0.137 -1.570 FEV (PET-1, HSRNAFEV)
TCF4_dimer.p2 -0.141 -1.819 TCF4 (E2-2, ITF2, PTHS, SEF2, SEF2-1, SEF2-1A, SEF2-1B, bHLHb19, MGC149723, MGC149724)
HMX1.p2 -0.143 -0.811 HMX1 (H6, NKX5-3)
MYFfamily.p2 -0.153 -2.450 MYOD1 (PUM, MYOD, bHLHc1)
MYF6 (MRF4, bHLHc4)
MYF5 (bHLHc2)
MYOG (bHLHc3)
AIRE.p2 -0.159 -0.332 AIRE (PGA1, APS1)
T.p2 -0.162 -0.230 T
DMAP1_NCOR{1,2}_SMARC.p2 -0.163 -0.573 SMARCA1 (SNF2LB, NURF140, ISWI, SWI)
SMARCC2 (BAF170, Rsc8, CRACC2)
SMARCA5 (hSNF2H, hISWI, ISWI)
NCOR1 (N-CoR, hCIT529I10, TRAC1, hN-CoR, KIAA1047, MGC104216)
NCOR2 (SMRT, SMRTE, TRAC-1, CTG26, TNRC14)
DMAP1 (DNMAP1, FLJ11543, KIAA1425, DNMTAP1, EAF2, SWC4)
FOXL1.p2 -0.166 -0.785 FOXL1 (FREAC7, FKH6)
STAT5{A,B}.p2 -0.171 -0.409 STAT5B
STAT5A (MGF)
PPARG.p2 -0.174 -0.290 PPARG (PPARG1, PPARG2, NR1C3, PPARgamma)
GLI1..3.p2 -0.178 -1.014 GLI1
GLI2 (THP2, HPE9, THP1)
GLI3 (PAP-A, PAPA, PAPA1, PAPB, ACLS, PPDIV)
NKX2-3_NKX2-5.p2 -0.183 -0.645 NKX2-5 (CSX1, NKX2.5, NKX4-1)
NKX2-3 (NKX2.3, CSX3, NKX4-3)
EWSR1-FLI1.p2 -0.189 -0.575 FLI1 (EWSR2, SIC-1)
EWSR1 (EWS, K984G1.4)
MYOD1.p2 -0.193 -1.572 MYOD1 (PUM, MYOD, bHLHc1)
ZNF423.p2 -0.194 -0.925 ZNF423 (KIAA0760, OAZ, Roaz, Ebfaz, Zfp104)
ESR1.p2 -0.194 -1.136 ESR1 (NR3A1, Era)
POU5F1.p2 -0.197 -1.221 POU5F1 (OCT3, Oct4, MGC22487)
STAT1,3.p3 -0.203 -0.333 STAT1 (STAT91, ISGF-3)
STAT3 (APRF)
RORA.p2 -0.209 -0.291 RORA (RZRA, ROR1, ROR2, ROR3, NR1F1)
RUNX1..3.p2 -0.210 -1.094 RUNX1 (PEBP2A2, AMLCR1)
RUNX3 (AML2, PEBP2A3)
RUNX2 (AML3, PEBP2A1, PEBP2aA1)
GFI1B.p2 -0.213 -0.486 GFI1B
LEF1_TCF7_TCF7L1,2.p2 -0.217 -0.893 TCF7 (TCF-1)
TCF7L2 (TCF-4)
LEF1 (TCF1ALPHA)
TCF7L1
EBF1.p2 -0.222 -1.603 EBF1 (OLF1)
RFX1..5_RFXANK_RFXAP.p2 -0.225 -1.296 RFX1 (EF-C)
RFXAP
RFX5
RFXANK (BLS, RFX-B, ANKRA1, F14150_1, MGC138628)
RFX4
RFX3
RFX2 (FLJ14226)
POU5F1_SOX2{dimer}.p2 -0.230 -0.605 POU5F1 (OCT3, Oct4, MGC22487)
SOX2
FOSL2.p2 -0.239 -0.781 FOSL2 (FRA2, FLJ23306)
POU1F1.p2 -0.245 -0.734 POU1F1 (GHF-1)
TBX4,5.p2 -0.246 -1.371 TBX5
TBX4
JUN.p2 -0.252 -1.616 JUN (c-Jun, AP-1)
JUND (AP-1)
JUNB
TLX1..3_NFIC{dimer}.p2 -0.256 -0.945 TLX1
TLX3 (RNX)
HLF.p2 -0.265 -0.656 HLF (MGC33822)
POU6F1.p2 -0.265 -0.535 POU6F1 (BRN5, MPOU, TCFB1)
HNF4A_NR2F1,2.p2 -0.268 -2.060 NR2F1 (EAR-3, COUP-TFI, TCFCOUP1, SVP44)
NR2F2 (COUP-TFII, COUPTFB, SVP40)
HNF4A (NR2A1, HNF4)
ZNF238.p2 -0.280 -0.776 ZNF238 (C2H2-171, TAZ-1, RP58, ZBTB18)
FOXA2.p3 -0.285 -1.022 FOXA2
FOX{F1,F2,J1}.p2 -0.295 -0.878 FOXF2 (FREAC2)
FOXJ1 (HFH-4, HFH4)
FOXF1 (FREAC1)
NR3C1.p2 -0.301 -0.640 NR3C1 (GR)
NANOG{mouse}.p2 -0.310 -0.751 NANOG (FLJ12581, FLJ40451)
SMAD1..7,9.p2 -0.314 -1.881 SMAD5 (Dwfc, JV5-1)
SMAD1 (MADR1, JV4-1)
SMAD3 (JV15-2, HsT17436)
SMAD4 (DPC4)
SMAD2 (MADR2, JV18-1)
SMAD6 (HsT17432)
SMAD7
SMAD9
PAX6.p2 -0.331 -0.296 PAX6 (D11S812E, AN, WAGR)
GTF2A1,2.p2 -0.338 -1.579 GTF2A1 (TFIIA)
GTF2A2 (TFIIA, HsT18745)
POU2F1..3.p2 -0.396 -1.345 POU2F2 (OCT2)
POU2F1 (OCT1)
POU2F3 (OCT11, PLA-1, Skn-1a, Epoc-1)
TGIF1.p2 -0.397 -1.786 TGIF1
NANOG.p2 -0.430 -1.030 NANOG (FLJ12581, FLJ40451)
HOX{A5,B5}.p2 -0.452 -1.362 HOXB5
HOXA5
EVI1.p2 -0.465 -1.938 EVI1 (MDS1-EVI1, PRDM3)
NR1H4.p2 -0.474 -1.736 NR1H4 (FXR, RIP14, HRR1, HRR-1)
RXRA_VDR{dimer}.p2 -0.477 -0.860 VDR (NR1I1)
FOX{C1,C2}.p2 -0.502 -0.939 FOXC1 (FREAC3, ARA, IGDA, IHG1)
FOXC2 (MFH-1)
EN1,2.p2 -0.531 -1.485 EN1
EN2
HAND1,2.p2 -0.724 -1.927 HAND1 (eHand, Thing1, Hxt, bHLHa27)
HAND2 (dHand, Thing2, Hed, bHLHa26)
NKX2-1,4.p2 -0.780 -1.128 NKX2-1 (TTF-1)
NKX2-4 (NKX2.4)
HNF1A.p2 -0.783 -1.812 HNF1A (HNF1, LFB1)
GATA6.p2 -0.812 -2.458 GATA6
FOXP3.p2 -0.835 -1.282 FOXP3 (JM2, XPID, AIID, PIDX, DIETER, SCURFIN)
PDX1.p2 -0.859 -0.809 PDX1 (IDX-1, STF-1, PDX-1, MODY4)
MSX1,2.p2 -0.926 -1.155 MSX1 (HYD1, OFC5)
MSX2 (CRS2, FPP, HOX8, MSH, PFM)
AR.p2 -1.519 -1.558 AR (AIS, NR3C4, SMAX1, HUMARA)
REST.p3 -1.613 -2.782 REST (NRSF, XBR)
PAX3,7.p2 -2.090 -0.747 PAX7 (Hup1)
PAX3 (HUP2)
PAX8.p2 -3.011 -0.891 PAX8