Motif ID: NR3C1.p2

Z-value: 0.779


Transcription factors associated with NR3C1.p2:

Gene SymbolEntrez IDGene Name
NR3C1 2908 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NR3C1chr5_-_142764168,
chr5_-_142762947
0.693.0e-03Click!


Activity profile for motif NR3C1.p2.

activity profile for motif NR3C1.p2


Sorted Z-values histogram for motif NR3C1.p2

Sorted Z-values for motif NR3C1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR3C1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_23252915 1.796 GPNMB
glycoprotein (transmembrane) nmb
chr7_+_23252911 1.678 GPNMB
glycoprotein (transmembrane) nmb
chr7_+_23252909 1.651 GPNMB
glycoprotein (transmembrane) nmb
chr10_+_91142301 1.385 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr17_-_43470134 1.356 NM_016429
COPZ2
coatomer protein complex, subunit zeta 2
chr7_-_124192265 1.332 GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr11_-_58099884 1.236 NM_004811
LPXN
leupaxin
chr10_+_70517823 1.162 NM_002727
SRGN
serglycin
chr22_+_21053972 0.964


chr14_-_105804211 0.948 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr11_+_5667494 0.898 NM_006074
TRIM22
tripartite motif containing 22
chr6_+_134251957 0.893 TCF21
transcription factor 21
chr8_+_54956069 0.890 RGS20
regulator of G-protein signaling 20
chr6_+_134251940 0.870 NM_198392
NM_003206
TCF21

transcription factor 21

chr7_+_23252802 0.846 NM_001005340
NM_002510
GPNMB

glycoprotein (transmembrane) nmb

chr20_+_42776888 0.757 WISP2
WNT1 inducible signaling pathway protein 2
chr6_-_6265874 0.748 F13A1
coagulation factor XIII, A1 polypeptide
chr14_-_105845570 0.718 IGHA1
immunoglobulin heavy constant alpha 1
chr6_+_36752244 0.670 NM_078467
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr6_-_6265896 0.664 NM_000129
F13A1
coagulation factor XIII, A1 polypeptide
chr14_-_106270497 0.660 IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr7_-_150576660 0.654 NM_001003801
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr2_-_37727472 0.634 CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr4_+_72423633 0.616 NM_003759
SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chrX_-_135577102 0.614 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr22_+_21042091 0.574 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr3_-_69212192 0.567 NM_003968
NM_198195
UBA3

ubiquitin-like modifier activating enzyme 3

chr18_-_51219880 0.561 TCF4
transcription factor 4
chr7_-_150576957 0.557 SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr6_-_76027286 0.547 TMEM30A
transmembrane protein 30A
chr1_+_160868932 0.542 DDR2
discoidin domain receptor tyrosine kinase 2
chr16_+_30293598 0.538 NM_013292
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr5_+_125786975 0.522 GRAMD3
GRAM domain containing 3
chr6_-_152681171 0.522 NM_015293
SYNE1
spectrin repeat containing, nuclear envelope 1
chr5_+_86600483 0.494 NM_022650
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr8_+_54955962 0.487 NM_003702
RGS20
regulator of G-protein signaling 20
chr11_-_104421240 0.456 NM_001017534
NM_052889
CARD16

CASP1
caspase recruitment domain family, member 16

caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
chr12_+_6925997 0.456 NM_080548
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr1_-_111544784 0.449 NM_024901
DENND2D
DENN/MADD domain containing 2D
chr17_-_31441390 0.445 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr10_-_101680645 0.439 DNMBP
dynamin binding protein
chr1_+_67168470 0.428 NM_001077701
NM_001077704
MIER1

mesoderm induction early response 1 homolog (Xenopus laevis)

chr1_-_205161821 0.417 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr17_-_45619038 0.404 COL1A1
collagen, type I, alpha 1
chr2_+_143603368 0.402 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr1_+_32512298 0.399 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr5_+_35892747 0.383 NM_002185
IL7R
interleukin 7 receptor
chr15_-_43458247 0.382 NM_001482
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr8_-_120720200 0.377 NM_001040092
NM_001130863
NM_006209
ENPP2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr14_-_106184988 0.376 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr7_+_93388951 0.375 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr12_+_6926014 0.368 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr17_-_9870292 0.366 NM_001130831
GAS7
growth arrest-specific 7
chr10_+_70517863 0.358 SRGN
serglycin
chrX_+_118598325 0.357 NM_181777
UBE2A
ubiquitin-conjugating enzyme E2A (RAD6 homolog)
chr7_-_87694218 0.354 NM_198901
SRI
sorcin
chr4_-_169476391 0.341 NM_017631
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr14_+_87541220 0.338 NM_003608
GPR65
G protein-coupled receptor 65
chr1_-_219977424 0.331 NM_144728
DUSP10
dual specificity phosphatase 10
chr13_+_75092570 0.330 NM_005358
LMO7
LIM domain 7
chr2_+_31310383 0.325 NM_014600
EHD3
EH-domain containing 3
chr5_-_169749215 0.321 NM_004137
KCNMB1
potassium large conductance calcium-activated channel, subfamily M, beta member 1
chr1_+_32417909 0.316 NM_175852
TXLNA
taxilin alpha
chr1_+_173111306 0.314 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr1_-_111544820 0.314 DENND2D
DENN/MADD domain containing 2D
chr3_-_45242072 0.312 TMEM158
transmembrane protein 158 (gene/pseudogene)
chr1_-_202726068 0.310 NM_002646
PIK3C2B
phosphoinositide-3-kinase, class 2, beta polypeptide
chr1_+_161305019 0.307 NM_001102445
RGS4
regulator of G-protein signaling 4
chr3_-_55490401 0.306 WNT5A
wingless-type MMTV integration site family, member 5A
chrX_+_128741578 0.298 SASH3
SAM and SH3 domain containing 3
chr22_+_42726423 0.298 NM_001003828
PARVB
parvin, beta
chr3_-_124822113 0.297 NM_053031
NM_053032
MYLK

myosin light chain kinase

chrX_+_128741562 0.295 NM_018990
SASH3
SAM and SH3 domain containing 3
chr1_+_160868822 0.287 NM_001014796
NM_006182
DDR2

discoidin domain receptor tyrosine kinase 2

chr3_+_45042754 0.284 NM_003278
CLEC3B
C-type lectin domain family 3, member B
chr11_-_8695974 0.283 ST5
suppression of tumorigenicity 5
chr1_+_111571803 0.282 NM_001025197
NM_004000
CHI3L2

chitinase 3-like 2

chr1_+_103961476 0.265 NM_000699
AMY2A
amylase, alpha 2A (pancreatic)
chr19_+_63262418 0.264 NM_001164527
NM_001164529
NM_001164530
NM_003436
NM_007134
ZNF135




zinc finger protein 135




chr19_+_44591589 0.246


chr4_-_170915602 0.241 NM_017867
C4orf27
chromosome 4 open reading frame 27
chr2_-_89073496 0.240 IGKC
immunoglobulin kappa constant
chr2_+_66516196 0.236 MEIS1
Meis homeobox 1
chr6_-_152542293 0.235 NM_133650
SYNE1
spectrin repeat containing, nuclear envelope 1
chr17_-_26665220 0.233 NM_006495
EVI2B
ecotropic viral integration site 2B
chr7_-_124192916 0.230 NM_005302
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr12_+_13240868 0.223 NM_001423
EMP1
epithelial membrane protein 1
chr1_+_158975662 0.220 NM_021181
SLAMF7
SLAM family member 7
chr6_+_35544155 0.216 NM_007104
RPL10A
ribosomal protein L10a
chr2_+_213857347 0.214 NM_001025436
NM_024532
SPAG16

sperm associated antigen 16

chr17_-_10265991 0.208 NM_002472
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
chr19_+_62844143 0.208 ZNF211
zinc finger protein 211
chr3_+_133798770 0.205 NM_016557
CCRL1
chemokine (C-C motif) receptor-like 1
chr3_+_49002774 0.204 P4HTM
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr13_+_100902942 0.203 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr3_+_16949585 0.203 NM_015184
PLCL2
phospholipase C-like 2
chr1_+_32417846 0.201 TXLNA
taxilin alpha
chr6_+_35544174 0.199 RPL10A
ribosomal protein L10a
chr5_+_140790310 0.199 NM_003735
NM_032094
PCDHGA12

protocadherin gamma subfamily A, 12

chr12_+_58276114 0.199 SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr3_+_99733432 0.197 NM_005290
GPR15
G protein-coupled receptor 15
chr9_+_101628829 0.196 NM_173200
NR4A3
nuclear receptor subfamily 4, group A, member 3
chrX_+_105932536 0.196 NM_017752
NM_198881
TBC1D8B

TBC1 domain family, member 8B (with GRAM domain)

chr5_+_140690387 0.193 NM_018912
NM_031993
PCDHGA1

protocadherin gamma subfamily A, 1

chr5_+_149867866 0.192 NM_001543
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr1_+_181380837 0.192 LAMC1
laminin, gamma 1 (formerly LAMB2)
chr11_+_10439253 0.188 NM_001172430
AMPD3
adenosine monophosphate deaminase 3
chr17_+_4784524 0.186 RNF167
ring finger protein 167
chr1_+_161305188 0.184 NM_005613
RGS4
regulator of G-protein signaling 4
chr2_-_158008763 0.183 NM_004288
CYTIP
cytohesin 1 interacting protein
chr2_-_175170674 0.181 WIPF1
WAS/WASL interacting protein family, member 1
chr6_-_24985432 0.180 NM_015864
FAM65B
family with sequence similarity 65, member B
chr4_+_169250281 0.180 NM_007193
ANXA10
annexin A10
chr5_+_125828685 0.179 NM_001146322
GRAMD3
GRAM domain containing 3
chr5_+_140742585 0.177 NM_018920
NM_032087
PCDHGA7

protocadherin gamma subfamily A, 7

chrX_+_100764757 0.175 NM_016607
NM_177947
ARMCX3

armadillo repeat containing, X-linked 3

chr8_-_78075834 0.174 NM_001172086
NM_001172087
PEX2

peroxisomal biogenesis factor 2

chr3_-_167037946 0.174 NM_000055
BCHE
butyrylcholinesterase
chr5_-_111121691 0.174 NM_001142477
NM_001142476
C5orf13

chromosome 5 open reading frame 13

chr7_+_20008870 0.172 RPL21
ribosomal protein L21
chr1_+_143807748 0.170 NM_004892
SEC22B
SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
chr20_+_29598848 0.170 HM13
histocompatibility (minor) 13
chrX_+_78087484 0.167 NM_014499
NM_198333
P2RY10

purinergic receptor P2Y, G-protein coupled, 10

chr1_+_169326641 0.166 NM_001002294
NM_006894
FMO3

flavin containing monooxygenase 3

chr6_+_32713160 0.165 NM_002122
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr11_+_57123927 0.162 SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr1_+_166461872 0.162 NM_199344
SFT2D2
SFT2 domain containing 2
chr2_-_45648608 0.161 SRBD1
S1 RNA binding domain 1
chr11_+_18390421 0.161 NM_002301
NM_017448
LDHC

lactate dehydrogenase C

chr11_-_26700121 0.157 NM_178498
SLC5A12
solute carrier family 5 (sodium/glucose cotransporter), member 12
chr9_+_115382760 0.153 NM_021106
RGS3
regulator of G-protein signaling 3
chr12_+_13240987 0.153 EMP1
epithelial membrane protein 1
chr7_+_142790047 0.152 ZYX
zyxin
chr4_+_15313670 0.152 NM_004334
BST1
bone marrow stromal cell antigen 1
chr17_-_30783631 0.147 NM_018042
SLFN12
schlafen family member 12
chr1_-_157950898 0.147 NM_000567
CRP
C-reactive protein, pentraxin-related
chr3_-_49374973 0.146 RHOA
ras homolog gene family, member A
chrX_+_2619224 0.145 NM_001122898
NM_002414
CD99

CD99 molecule

chrY_+_2619224 0.145 NM_001122898
NM_002414
CD99

CD99 molecule

chr1_+_144374513 0.145 RNF115
ring finger protein 115
chr14_+_65205750 0.142 NM_178157
FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr4_+_54790190 0.142 PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr17_-_59363352 0.142 NM_000626
NM_001039933
NM_021602
CD79B


CD79b molecule, immunoglobulin-associated beta


chr19_-_48401532 0.139 NM_002780
NM_213633
PSG4

pregnancy specific beta-1-glycoprotein 4

chrX_+_149364377 0.139 NM_001177466
NM_005491
MAMLD1

mastermind-like domain containing 1

chrX_+_65299157 0.138 NM_138737
HEPH
hephaestin
chr20_+_62164900 0.136 TCEA2
transcription elongation factor A (SII), 2
chr7_-_86812629 0.135 TP53TG1
TP53 target 1 (non-protein coding)
chr3_+_185375362 0.134 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr13_-_32757835 0.134 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr1_-_199657468 0.132 NM_003281
TNNI1
troponin I type 1 (skeletal, slow)
chr10_+_91077581 0.131 NM_001549
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr12_-_55990512 0.131 NM_014925
R3HDM2
R3H domain containing 2
chr1_+_166461881 0.130 SFT2D2
SFT2 domain containing 2
chr3_-_167037861 0.130 BCHE
butyrylcholinesterase
chr11_+_67532592 0.130 NM_001161473
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr1_+_13588674 0.126 NM_001099851
PRAMEF17
PRAME family member 17
chr19_-_48382398 0.125 NM_001130014
NM_002781
PSG5

pregnancy specific beta-1-glycoprotein 5

chr1_+_161305558 0.120 NM_001113381
RGS4
regulator of G-protein signaling 4
chr11_-_116692128 0.120 NM_012104
NM_138971
NM_138972
NM_138973
BACE1



beta-site APP-cleaving enzyme 1



chr2_+_43854681 0.117 NM_001193464
NM_015522
NM_016008
DYNC2LI1


dynein, cytoplasmic 2, light intermediate chain 1


chrX_-_10605726 0.117 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr14_-_106137250 0.116


chr8_-_108579270 0.115 NM_001146
ANGPT1
angiopoietin 1
chr3_-_120761092 0.114 NM_005191
CD80
CD80 molecule
chr4_+_114190233 0.114 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr3_+_185375356 0.113 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr6_-_33016561 0.112 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr20_-_4743768 0.112 NM_170774
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr9_+_130427988 0.110 SPTAN1
spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
chr21_+_42792810 0.109 NM_018964
SLC37A1
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr3_-_124821868 0.108 MYLK
myosin light chain kinase
chr22_+_39404940 0.108 NM_005297
MCHR1
melanin-concentrating hormone receptor 1
chr5_-_149649380 0.107 CAMK2A
calcium/calmodulin-dependent protein kinase II alpha
chr9_+_115382990 0.105 RGS3
regulator of G-protein signaling 3
chr12_-_9804682 0.103 NM_001781
CD69
CD69 molecule
chr7_-_122627235 0.103 NM_022444
SLC13A1
solute carrier family 13 (sodium/sulfate symporters), member 1
chr5_-_42847716 0.102 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr5_+_140541163 0.102 NM_020957
PCDHB16
protocadherin beta 16
chr3_+_70068440 0.099 NM_000248
NM_001184968
NM_198158
NM_198178
MITF



microphthalmia-associated transcription factor



chr11_-_8788765 0.099 NM_213618
ST5
suppression of tumorigenicity 5
chr10_+_97505398 0.097 NM_001164178
NM_001164181
NM_001164179
NM_001164182
NM_001164183
NM_001776
ENTPD1





ectonucleoside triphosphate diphosphohydrolase 1





chr7_+_129720209 0.097 NM_001163446
NM_016352
CPA4

carboxypeptidase A4

chrX_+_65299352 0.095 HEPH
hephaestin
chr15_+_22652790 0.092 NM_022805
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr3_-_147696411 0.091 NM_020359
PLSCR2
phospholipid scramblase 2
chr20_-_18425811 0.091 NM_006606
RBBP9
retinoblastoma binding protein 9
chr3_+_185375370 0.091 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr1_+_74473672 0.090 NM_015978
TNNI3K
TNNI3 interacting kinase
chr3_-_184316553 0.088 MCCC1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr3_+_35697432 0.087 NM_198399
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr7_+_55054416 0.087 EGFR
epidermal growth factor receptor
chr3_+_185375341 0.087 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr16_-_20246309 0.085 NM_001007240
NM_001007241
NM_001007242
NM_001502
GP2



glycoprotein 2 (zymogen granule membrane)



chr18_+_28023984 0.084 NM_005925
MEP1B
meprin A, beta
chr5_+_67622242 0.083 NM_181504
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr1_-_35957314 0.083 NM_152374
C1orf216
chromosome 1 open reading frame 216
chr10_+_170423 0.082 NM_001161482
NM_006624
NM_212479
ZMYND11


zinc finger, MYND-type containing 11


chr6_-_22410993 0.081 NM_001163558
PRL
prolactin
chr12_+_54396118 0.080 BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.