Motif ID: ZEB1.p2

Z-value: 2.596


Transcription factors associated with ZEB1.p2:

Gene SymbolEntrez IDGene Name
ZEB1 6935 zinc finger E-box binding homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZEB1chr10_+_31647425-0.844.9e-05Click!


Activity profile for motif ZEB1.p2.

activity profile for motif ZEB1.p2


Sorted Z-values histogram for motif ZEB1.p2

Sorted Z-values for motif ZEB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZEB1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_43446937 8.570 NM_001166103
NM_021102
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr19_+_43447078 8.522 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_43447262 7.658 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr7_+_26298018 7.242 NM_013322
SNX10
sorting nexin 10
chr4_+_75529716 6.213 NM_001657
AREG
amphiregulin
chr2_+_47449790 5.938 NM_002354
EPCAM
epithelial cell adhesion molecule
chr7_+_26298136 5.505 SNX10
sorting nexin 10
chr2_+_47449951 5.136 EPCAM
epithelial cell adhesion molecule
chr6_+_7486836 5.096 DSP
desmoplakin
chr6_+_7486862 5.007 NM_001008844
NM_004415
DSP

desmoplakin

chr6_+_7486891 4.896 DSP
desmoplakin
chr4_+_75699652 4.788 NM_001657
AREG
amphiregulin
chr20_-_6051562 4.672 FERMT1
fermitin family member 1
chr19_+_40431359 4.405 NM_015925
NM_205834
NM_205835
LSR


lipolysis stimulated lipoprotein receptor


chr18_+_27332024 4.387 NM_001943
DSG2
desmoglein 2
chr16_+_67328693 4.309 NM_004360
CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr2_-_166359016 4.161 NM_004482
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr19_+_40431618 3.859 LSR
lipolysis stimulated lipoprotein receptor
chr8_+_95722448 3.597 ESRP1
epithelial splicing regulatory protein 1
chrX_+_152562013 3.562 DUSP9
dual specificity phosphatase 9
chr21_-_42060266 3.444 NM_020639
RIPK4
receptor-interacting serine-threonine kinase 4
chr17_-_37196463 3.400 NM_002230
NM_021991
JUP

junction plakoglobin

chr16_+_67236730 3.365 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr19_+_40431122 3.335 LSR
lipolysis stimulated lipoprotein receptor
chr21_-_42060334 3.298 RIPK4
receptor-interacting serine-threonine kinase 4
chr14_-_66948523 3.283 NM_016445
PLEK2
pleckstrin 2
chr14_-_66948612 3.246 PLEK2
pleckstrin 2
chr2_+_17585287 3.110 NM_003385
VSNL1
visinin-like 1
chr1_+_1971762 3.104 NM_002744
PRKCZ
protein kinase C, zeta
chr2_+_17585462 3.000 VSNL1
visinin-like 1
chrX_+_130985316 2.963 NM_001042452
MST4
serine/threonine protein kinase MST4
chr19_+_40431678 2.946 LSR
lipolysis stimulated lipoprotein receptor
chr16_+_67328715 2.935 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr11_+_32808045 2.733 NM_024081
PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr8_+_86563382 2.711 NM_000067
CA2
carbonic anhydrase II
chr5_+_76150588 2.478 NM_005242
F2RL1
coagulation factor II (thrombin) receptor-like 1
chr20_+_60918836 2.455 NM_001853
COL9A3
collagen, type IX, alpha 3
chr6_-_10527772 2.366 NM_001042425
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr16_-_66827449 2.338 NM_024939
ESRP2
epithelial splicing regulatory protein 2
chr5_+_167651063 2.296 NM_001161661
NM_001161662
NM_015238
WWC1


WW and C2 domain containing 1


chr17_+_71033339 2.279 NM_001015002
NM_001031803
NM_004524
LLGL2


lethal giant larvae homolog 2 (Drosophila)


chr20_-_10602139 2.230 JAG1
jagged 1
chr14_-_60817709 2.230 TMEM30B
transmembrane protein 30B
chr11_+_696103 2.221 NM_022772
EPS8L2
EPS8-like 2
chr11_-_70837019 2.215 DHCR7
7-dehydrocholesterol reductase
chr3_-_45162865 2.192 CDCP1
CUB domain containing protein 1
chr7_-_22363036 2.184 NM_012294
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr17_+_71229110 2.184 NM_000213
NM_001005731
ITGB4

integrin, beta 4

chr4_-_35922288 2.151 NM_015230
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr10_+_124124196 2.150 PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr12_-_51200347 2.139 NM_000424
KRT5
keratin 5
chr11_+_712282 2.122 EPS8L2
EPS8-like 2
chr1_-_58815415 2.087 TACSTD2
tumor-associated calcium signal transducer 2
chr1_+_60053050 2.059 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr3_-_45162847 2.021 CDCP1
CUB domain containing protein 1
chr2_-_20288647 2.019 NM_001006946
SDC1
syndecan 1
chr17_+_71229151 2.006 ITGB4
integrin, beta 4
chr3_-_45162901 2.001 NM_022842
NM_178181
CDCP1

CUB domain containing protein 1

chr2_-_20288108 1.992 NM_002997
SDC1
syndecan 1
chr16_-_11588257 1.950 NM_001136472
NM_001136473
LITAF

lipopolysaccharide-induced TNF factor

chr2_-_216586488 1.949 NM_018000
MREG
melanoregulin
chr16_-_11588525 1.940 LITAF
lipopolysaccharide-induced TNF factor
chr5_+_76150637 1.919 F2RL1
coagulation factor II (thrombin) receptor-like 1
chr18_+_59295123 1.887 NM_002639
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr20_-_10602429 1.827 NM_000214
JAG1
jagged 1
chr14_-_60818263 1.788 NM_001017970
TMEM30B
transmembrane protein 30B
chr14_+_100270222 1.764 DLK1
delta-like 1 homolog (Drosophila)
chr17_+_71229191 1.758 ITGB4
integrin, beta 4
chr3_+_187813538 1.725 NM_001622
AHSG
alpha-2-HS-glycoprotein
chr6_+_36206239 1.712 NM_002754
MAPK13
mitogen-activated protein kinase 13
chr1_+_181422016 1.697 LAMC2
laminin, gamma 2
chr19_-_56178882 1.685 NM_139277
NM_005046
KLK7

kallikrein-related peptidase 7

chr14_+_30413393 1.680 NM_001135058
NM_004086
COCH

coagulation factor C homolog, cochlin (Limulus polyphemus)

chr20_+_43468046 1.646 NM_001197139
NM_001048221
NM_001048222
NM_001197140
NM_018478
DBNDD2




dysbindin (dystrobrevin binding protein 1) domain containing 2




chr2_+_162908828 1.637 NM_012198
GCA
grancalcin, EF-hand calcium binding protein
chr17_-_77634455 1.626 FASN
fatty acid synthase
chr3_+_187813553 1.589 AHSG
alpha-2-HS-glycoprotein
chr17_-_77635703 1.581 FASN
fatty acid synthase
chr20_+_25176698 1.572 NM_002862
PYGB
phosphorylase, glycogen; brain
chr3_+_187813405 1.532 AHSG
alpha-2-HS-glycoprotein
chr6_-_47385313 1.488 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr10_+_124124083 1.484 NM_001001974
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr19_-_56214765 1.482 NM_145888
KLK10
kallikrein-related peptidase 10
chr6_-_47385205 1.463 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr7_+_115637795 1.449 NM_015641
TES
testis derived transcript (3 LIM domains)
chr12_+_54760211 1.440 ERBB3
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
chr6_-_47385605 1.422 NM_014452
TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr12_+_54760153 1.415 NM_001005915
NM_001982
ERBB3

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

chr6_-_47385470 1.385 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chrX_+_152608159 1.383 NM_001142806
SLC6A8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr3_-_191321367 1.365 LEPREL1
leprecan-like 1
chr2_-_165186232 1.359 GRB14
growth factor receptor-bound protein 14
chr20_+_43468617 1.350 NM_001048223
NM_001048224
DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chr4_+_4439705 1.348 D4S234E
DNA segment on chromosome 4 (unique) 234 expressed sequence
chr1_+_152644292 1.339 NM_000565
NM_181359
IL6R

interleukin 6 receptor

chr12_+_56271181 1.326 NM_001146258
NM_001146259
NM_001146260
NM_024779
PIP4K2C



phosphatidylinositol-5-phosphate 4-kinase, type II, gamma



chr2_-_165186064 1.318 GRB14
growth factor receptor-bound protein 14
chr17_-_36938025 1.292 KRT19
keratin 19
chr12_+_56271259 1.279 PIP4K2C
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr19_+_7608010 1.273 STXBP2
syntaxin binding protein 2
chr1_-_159257567 1.269 F11R
F11 receptor
chr11_+_120828058 1.266 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr11_-_114880275 1.265 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr8_+_95722516 1.261 NM_001034915
NM_001122825
NM_001122826
NM_001122827
NM_017697
ESRP1




epithelial splicing regulatory protein 1




chr8_+_95722575 1.259 ESRP1
epithelial splicing regulatory protein 1
chr18_-_19420438 1.253 NM_000271
NPC1
Niemann-Pick disease, type C1
chr4_+_79691765 1.241 NM_005139
ANXA3
annexin A3
chr11_-_70837090 1.240 NM_001163817
NM_001360
DHCR7

7-dehydrocholesterol reductase

chr16_+_67236699 1.238 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr20_+_60744231 1.218 NM_016354
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr18_-_19420376 1.217 NPC1
Niemann-Pick disease, type C1
chr4_+_128922852 1.215 NM_014278
HSPA4L
heat shock 70kDa protein 4-like
chr19_+_7608015 1.211 STXBP2
syntaxin binding protein 2
chr19_+_40299058 1.210 FXYD3
FXYD domain containing ion transport regulator 3
chr4_+_85723080 1.209 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr17_+_2627099 1.208 RAP1GAP2
RAP1 GTPase activating protein 2
chr4_-_152155827 1.204 LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr20_+_43425153 1.200 NM_001099791
NM_033542
SYS1-DBNDD2
SYS1

SYS1-DBNDD2 read-through transcript
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)

chr3_+_143797895 1.195 NM_001145319
PLS1
plastin 1
chr2_+_162908869 1.192 GCA
grancalcin, EF-hand calcium binding protein
chr2_+_215885063 1.189 ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr8_-_145609737 1.186 SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr1_-_159257486 1.182 F11R
F11 receptor
chr1_+_181421796 1.176 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr4_-_56996400 1.175 NM_002703
PPAT
phosphoribosyl pyrophosphate amidotransferase
chr12_-_109424260 1.169 NM_016226
NM_057180
VPS29

vacuolar protein sorting 29 homolog (S. cerevisiae)

chr17_+_38064787 1.168 NM_016437
TUBG2
tubulin, gamma 2
chr12_-_28014151 1.166 NM_198964
NM_198966
PTHLH

parathyroid hormone-like hormone

chr19_+_7607976 1.153 NM_001127396
NM_006949
STXBP2

syntaxin binding protein 2

chr11_+_67836575 1.150 NM_002335
LRP5
low density lipoprotein receptor-related protein 5
chr5_-_1577022 1.143 NM_024830
LPCAT1
lysophosphatidylcholine acyltransferase 1
chr3_-_8668723 1.140 NM_015931
C3orf32
chromosome 3 open reading frame 32
chr2_-_121759237 1.139 NM_014553
TFCP2L1
transcription factor CP2-like 1
chr1_+_109594163 1.136 NM_001408
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr17_+_52517529 1.132 NM_003488
AKAP1
A kinase (PRKA) anchor protein 1
chr8_-_110726201 1.127 NM_001099753
NM_001099754
NM_001099755
SYBU


syntabulin (syntaxin-interacting)


chr1_+_181421984 1.115 LAMC2
laminin, gamma 2
chr16_-_4927057 1.105 NM_002705
PPL
periplakin
chr16_+_1668284 1.087 HN1L
hematological and neurological expressed 1-like
chr1_-_27113018 1.084 NM_021969
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr17_+_77529070 1.077 ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr16_+_1668257 1.066 NM_144570
HN1L
hematological and neurological expressed 1-like
chr17_+_77528782 1.066 ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr7_+_16759845 1.052 NM_014399
TSPAN13
tetraspanin 13
chr1_+_161027115 1.048 NM_016371
HSD17B7
hydroxysteroid (17-beta) dehydrogenase 7
chr4_+_4439618 1.040 D4S234E
DNA segment on chromosome 4 (unique) 234 expressed sequence
chr6_+_30402203 1.034


chr17_-_77649322 1.024 FASN
fatty acid synthase
chr7_-_51351952 1.004 NM_015198
COBL
cordon-bleu homolog (mouse)
chrX_-_152804731 1.001 L1CAM
L1 cell adhesion molecule
chr20_-_6052056 0.995 NM_017671
FERMT1
fermitin family member 1
chr9_-_99994704 0.995 NM_052820
CORO2A
coronin, actin binding protein, 2A
chr17_+_77528699 0.990 NM_024083
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr1_+_46418786 0.982 TSPAN1
tetraspanin 1
chr14_+_64240902 0.978 NM_015549
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr18_+_53967544 0.978 NM_001144965
NM_001144968
NM_001144969
NM_001144971
NEDD4L



neural precursor cell expressed, developmentally down-regulated 4-like



chr4_+_89519134 0.977 HERC6
hect domain and RLD 6
chr13_+_27092846 0.972 POLR1D
polymerase (RNA) I polypeptide D, 16kDa
chr1_-_218168137 0.968 SLC30A10
solute carrier family 30, member 10
chr12_-_61614930 0.964 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr19_+_43971689 0.963 NM_001042507
LGALS7B
lectin, galactoside-binding, soluble, 7B
chr2_+_64534774 0.960 NM_014181
HSPC159
galectin-related protein
chr11_+_69602055 0.957 NM_018043
ANO1
anoctamin 1, calcium activated chloride channel
chr15_+_48261649 0.954 NM_001159629
NM_003645
SLC27A2

solute carrier family 27 (fatty acid transporter), member 2

chr19_-_51909416 0.951 NM_001079882
PRKD2
protein kinase D2
chr4_+_128922930 0.948 HSPA4L
heat shock 70kDa protein 4-like
chr1_+_26744893 0.945 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr4_+_89519004 0.939 HERC6
hect domain and RLD 6
chr16_-_51139214 0.927 NM_001146188
TOX3
TOX high mobility group box family member 3
chr8_-_81246215 0.924 NM_001025253
NM_005079
TPD52

tumor protein D52

chr18_+_11679135 0.924 NM_182978
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr17_-_2561676 0.922 NM_015229
KIAA0664
KIAA0664
chr3_-_31998241 0.913 NM_001174060
NM_017784
OSBPL10

oxysterol binding protein-like 10

chr2_+_118562499 0.912 NM_016133
INSIG2
insulin induced gene 2
chr1_+_26744929 0.912 NM_001006665
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr4_+_4439750 0.907 D4S234E
DNA segment on chromosome 4 (unique) 234 expressed sequence
chr1_-_159275357 0.907 NM_001113205
NM_001113206
NM_001113207
TSTD1


F11R
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1


F11 receptor
chr20_+_309272 0.906 NM_021158
TRIB3
tribbles homolog 3 (Drosophila)
chr5_-_74198370 0.904 NM_015566
FAM169A
family with sequence similarity 169, member A
chr12_-_51173238 0.897 NM_005554
KRT6A
keratin 6A
chr4_+_89518898 0.893 NM_001165136
NM_017912
HERC6

hect domain and RLD 6

chr1_-_58815753 0.886 NM_002353
TACSTD2
tumor-associated calcium signal transducer 2
chr19_+_7608020 0.885 STXBP2
syntaxin binding protein 2
chr10_+_38685299 0.873 HSD17B7P2
hydroxysteroid (17-beta) dehydrogenase 7 pseudogene 2
chr1_+_39229474 0.870 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr7_+_94374862 0.867 NM_001166160
NM_017650
PPP1R9A

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr17_+_62804385 0.866 NM_012417
NM_181671
PITPNC1

phosphatidylinositol transfer protein, cytoplasmic 1

chr16_-_51138306 0.866 NM_001080430
TOX3
TOX high mobility group box family member 3
chr1_-_159275334 0.857 TSTD1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr5_+_271355 0.846 NM_004168
SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr14_-_20636337 0.841 ZNF219
zinc finger protein 219
chr10_-_118754717 0.840 KIAA1598
KIAA1598
chr3_+_168936125 0.840 NM_001122752
NM_005025
SERPINI1

serpin peptidase inhibitor, clade I (neuroserpin), member 1

chr12_-_116021473 0.839 NM_001168325
NM_017899
TESC

tescalcin

chr19_+_8415875 0.831 HNRNPM
heterogeneous nuclear ribonucleoprotein M
chr4_-_15694764 0.822 PROM1
prominin 1
chr3_-_191321601 0.818 NM_018192
LEPREL1
leprecan-like 1
chr3_-_56810869 0.814 NM_019555
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr9_-_5822840 0.812 ERMP1
endoplasmic reticulum metallopeptidase 1
chr16_-_66252103 0.806 NM_001082486
NM_001082487
NM_022914
ACD


adrenocortical dysplasia homolog (mouse)



Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.34 4.37e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.34 2.10e-02 GO:0016301 kinase activity
1.35 3.22e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.23 3.54e-02 GO:0032559 adenyl ribonucleotide binding
1.23 3.84e-02 GO:0030554 adenyl nucleotide binding