Motif ID: BPTF.p2

Z-value: 0.973


Transcription factors associated with BPTF.p2:

Gene SymbolEntrez IDGene Name
BPTF 2186 bromodomain PHD finger transcription factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
BPTFchr17_+_63252668,
chr17_+_63252704
0.136.4e-01Click!


Activity profile for motif BPTF.p2.

activity profile for motif BPTF.p2


Sorted Z-values histogram for motif BPTF.p2

Sorted Z-values for motif BPTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of BPTF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_45654327 3.422 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr13_-_45654296 2.962 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr4_+_39874921 2.309 NM_004310
RHOH
ras homolog gene family, member H
chr13_-_45654292 2.297 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr12_-_7935010 1.830 SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14
chr1_-_25164061 1.487 NM_001031680
RUNX3
runt-related transcription factor 3
chr16_+_28850760 1.430 NM_001178098
NM_001770
CD19

CD19 molecule

chr1_-_158948176 1.218 NM_001778
CD48
CD48 molecule
chr4_-_40212670 1.014 NM_019027
RBM47
RNA binding motif protein 47
chr22_+_21079355 1.001


chrX_+_47999740 0.998 NM_005635
SSX1
synovial sarcoma, X breakpoint 1
chr8_-_38127489 0.976 NM_000349
STAR
steroidogenic acute regulatory protein
chr14_-_105476678 0.938 IGHM
immunoglobulin heavy constant mu
chr5_+_75734759 0.926 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr4_-_88531353 0.866 NM_016245
HSD17B11
hydroxysteroid (17-beta) dehydrogenase 11
chr5_-_150583808 0.860 CCDC69
coiled-coil domain containing 69
chr14_+_20319049 0.860 NM_005615
RNASE6
ribonuclease, RNase A family, k6
chr13_-_98757634 0.857 NM_004951
GPR183
G protein-coupled receptor 183
chr5_+_168996816 0.853 NM_004946
DOCK2
dedicator of cytokinesis 2
chr1_+_111571803 0.824 NM_001025197
NM_004000
CHI3L2

chitinase 3-like 2

chr2_+_215884923 0.800 NM_004044
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr4_+_106851415 0.798 NM_001031720
GSTCD
glutathione S-transferase, C-terminal domain containing
chr5_-_176769094 0.774 F12
coagulation factor XII (Hageman factor)
chr5_-_150583842 0.771 NM_015621
CCDC69
coiled-coil domain containing 69
chr19_+_12995782 0.754 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr19_+_10223598 0.746 NM_015956
NM_146387
NM_146388
MRPL4


mitochondrial ribosomal protein L4


chr12_+_116938888 0.744 NM_001130112
NM_001130113
NM_007370
NM_181578
RFC5



replication factor C (activator 1) 5, 36.5kDa



chr3_-_126325132 0.721 SLC12A8
solute carrier family 12 (potassium/chloride transporters), member 8
chr8_-_71743973 0.712 NM_016027
LACTB2
lactamase, beta 2
chr10_-_69267774 0.711 NM_021800
NM_201262
DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr3_+_188222337 0.711 NM_003032
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr12_-_55432348 0.659 NM_000946
PRIM1
primase, DNA, polypeptide 1 (49kDa)
chr9_+_99303282 0.657 NM_001166116
TMOD1
tropomodulin 1
chr7_+_28692122 0.652 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr6_+_12825818 0.639 NM_030948
PHACTR1
phosphatase and actin regulator 1
chr15_-_53349775 0.634 NM_183234
NM_004580
RAB27A

RAB27A, member RAS oncogene family

chrX_+_7770302 0.631 NM_013452
VCX
variable charge, X-linked
chr1_+_196874867 0.609 PTPRC
protein tyrosine phosphatase, receptor type, C
chr1_-_45224784 0.607 EIF2B3
eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
chr4_-_88531245 0.604 HSD17B11
hydroxysteroid (17-beta) dehydrogenase 11
chr3_-_184363157 0.601 NM_014398
LAMP3
lysosomal-associated membrane protein 3
chr6_-_154692906 0.599 NM_001130699
IPCEF1
interaction protein for cytohesin exchange factors 1
chr20_-_47963682 0.598 NM_001135773
SPATA2
spermatogenesis associated 2
chr2_+_215885053 0.595 ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr16_-_73258276 0.591 NM_018124
RFWD3
ring finger and WD repeat domain 3
chr14_+_101345878 0.590 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr6_+_32713160 0.588 NM_002122
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr19_+_62972808 0.580 NM_017652
ZNF586
zinc finger protein 586
chr2_-_151854619 0.566 NM_004688
NMI
N-myc (and STAT) interactor
chr15_+_87588188 0.565 NM_001113378
NM_018193
FANCI

Fanconi anemia, complementation group I

chr1_-_45224853 0.563 NM_001166588
NM_020365
EIF2B3

eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa

chr4_+_170817787 0.559 CLCN3
chloride channel 3
chr1_+_12002098 0.551 NM_021933
MIIP
migration and invasion inhibitory protein
chr3_+_70068440 0.546 NM_000248
NM_001184968
NM_198158
NM_198178
MITF



microphthalmia-associated transcription factor



chr22_+_38652555 0.543 GRAP2
GRB2-related adaptor protein 2
chr4_-_46605980 0.540 NM_130902
COX7B2
cytochrome c oxidase subunit VIIb2
chr17_-_26665220 0.538 NM_006495
EVI2B
ecotropic viral integration site 2B
chr10_+_11246934 0.527 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr17_-_26665194 0.517 EVI2B
ecotropic viral integration site 2B
chr19_-_6542012 0.517 CD70
CD70 molecule
chr17_-_26665144 0.513 EVI2B
ecotropic viral integration site 2B
chr19_+_52504914 0.510 NM_001736
C5AR1
complement component 5a receptor 1
chr14_+_102672745 0.509 TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr22_+_21053972 0.508


chrX_+_23982992 0.506 EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr15_+_87588230 0.504 FANCI
Fanconi anemia, complementation group I
chr17_-_26665213 0.495 EVI2B
ecotropic viral integration site 2B
chr12_+_25096472 0.491 NM_006152
LRMP
lymphoid-restricted membrane protein
chrX_-_47941142 0.489 NM_021015
NM_175723
SSX5

synovial sarcoma, X breakpoint 5

chr4_-_176970895 0.487 GPM6A
glycoprotein M6A
chr1_+_78858675 0.486 NM_006820
IFI44L
interferon-induced protein 44-like
chrX_-_11194015 0.485 NM_013423
ARHGAP6
Rho GTPase activating protein 6
chr18_+_27925923 0.475 RNF138
ring finger protein 138
chr12_-_122272346 0.469 NM_022782
MPHOSPH9
M-phase phosphoprotein 9
chrX_-_118610880 0.467 NM_001173488
NKRF
NFKB repressing factor
chr17_+_65009986 0.466 MAP2K6
mitogen-activated protein kinase kinase 6
chrX_+_23982981 0.465 NM_001415
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chrX_-_52562712 0.465 NM_001097598
NM_001097597
NM_001097605
NM_001097604
NM_001097593
NM_001097592
NM_001097596
NM_001097594
NM_133430
NM_020411
XAGE1C

XAGE1E

XAGE1A

XAGE1B

XAGE1D

X antigen family, member 1C

X antigen family, member 1E

X antigen family, member 1A

X antigen family, member 1B

X antigen family, member 1D

chr6_-_26164478 0.463 NM_005319
HIST1H1C
histone cluster 1, H1c
chr12_-_7979896 0.463 NM_006931
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr6_+_42857540 0.462 KIAA0240
KIAA0240
chr6_+_64414389 0.452 NM_015153
PHF3
PHD finger protein 3
chr11_-_71822991 0.452 NM_030813
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr11_-_77026406 0.447 NM_001293
CLNS1A
chloride channel, nucleotide-sensitive, 1A
chr15_+_47249700 0.443 NM_002044
GALK2
galactokinase 2
chr13_+_49100435 0.442 NM_138450
ARL11
ADP-ribosylation factor-like 11
chr19_-_6542136 0.442 NM_001252
CD70
CD70 molecule
chrX_-_52549818 0.441 NM_001097598
NM_001097597
NM_001097605
NM_001097604
NM_001097593
NM_001097592
NM_001097596
NM_001097594
NM_133430
NM_020411
XAGE1C

XAGE1E

XAGE1A

XAGE1B

XAGE1D

X antigen family, member 1C

X antigen family, member 1E

X antigen family, member 1A

X antigen family, member 1B

X antigen family, member 1D

chr15_-_32398220 0.441 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr7_-_134506070 0.436 NM_024033
C7orf49
chromosome 7 open reading frame 49
chr5_+_43645018 0.435 NNT
nicotinamide nucleotide transhydrogenase
chr10_+_11247059 0.435 CELF2
CUGBP, Elav-like family member 2
chr1_-_27825178 0.433 NM_001042747
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr2_-_171631728 0.432 NM_001136555
TLK1
tousled-like kinase 1
chr15_-_41904059 0.432 NM_005926
MFAP1
microfibrillar-associated protein 1
chrX_-_48655978 0.431 PIM2
pim-2 oncogene
chr1_-_9052207 0.427 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr19_+_10258642 0.426 NM_001039132
NM_001544
NM_022377
ICAM4


intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)


chr19_-_6542082 0.425 CD70
CD70 molecule
chr19_-_44014228 0.422 NM_001398
ECH1
enoyl CoA hydratase 1, peroxisomal
chr4_+_53986759 0.406 FIP1L1
FIP1 like 1 (S. cerevisiae)
chr1_-_148126089 0.406 NM_175065
HIST2H2AB
HIST2H2BE
histone cluster 2, H2ab
histone cluster 2, H2be
chr17_+_17147351 0.404 NM_020201
NT5M
5',3'-nucleotidase, mitochondrial
chr12_-_120276394 0.401 NM_001137559
ANAPC5
anaphase promoting complex subunit 5
chr5_+_37415149 0.395 NM_018034
WDR70
WD repeat domain 70
chr11_-_71823217 0.391 CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr9_-_122728173 0.390 TRAF1
TNF receptor-associated factor 1
chr18_+_27925815 0.390 NM_016271
RNF138
ring finger protein 138
chr7_-_99537362 0.386 NM_005916
MCM7
minichromosome maintenance complex component 7
chr2_-_158008763 0.386 NM_004288
CYTIP
cytohesin 1 interacting protein
chr5_+_132456293 0.383 HSPA4
heat shock 70kDa protein 4
chr17_-_1195096 0.380 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr12_-_51887266 0.378 NM_000889
ITGB7
integrin, beta 7
chr19_+_62972861 0.374 ZNF586
zinc finger protein 586
chr5_+_102493155 0.370 NM_015216
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr7_-_25234582 0.370 NM_022150
NPVF
neuropeptide VF precursor
chr4_-_38482805 0.366 NM_003263
TLR1
toll-like receptor 1
chr17_-_39094427 0.365 NM_004527
NM_013999
MEOX1

mesenchyme homeobox 1

chr4_-_71751070 0.360 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr1_+_196874759 0.358 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr11_-_73371531 0.357 NM_003355
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr6_+_170705345 0.352 NM_001172085
NM_003194
TBP

TATA box binding protein

chr15_-_35180656 0.351 NM_002399
MEIS2
Meis homeobox 2
chr12_+_25096755 0.350 LRMP
lymphoid-restricted membrane protein
chr9_+_127002671 0.348 NM_005833
RABEPK
Rab9 effector protein with kelch motifs
chr6_-_31668476 0.348 NM_001145466
NM_001145467
NM_147130
NCR3


natural cytotoxicity triggering receptor 3


chr6_-_32206029 0.345 NM_022110
FKBPL
FK506 binding protein like
chr17_-_64462976 0.345 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr12_-_101398429 0.344 IGF1
insulin-like growth factor 1 (somatomedin C)
chr4_-_17415918 0.344 DCAF16
DDB1 and CUL4 associated factor 16
chr19_+_10223852 0.344 MRPL4
mitochondrial ribosomal protein L4
chr5_+_37415139 0.340 WDR70
WD repeat domain 70
chr19_-_10311262 0.335 NM_002162
ICAM3
intercellular adhesion molecule 3
chrX_+_48640718 0.335 NM_001167992
PQBP1
polyglutamine binding protein 1
chr12_-_51887318 0.334 ITGB7
integrin, beta 7
chrX_-_138114846 0.332 NM_001139498
NM_001139500
NM_001139501
FGF13


fibroblast growth factor 13


chr5_+_68703036 0.332 NM_133339
RAD17
RAD17 homolog (S. pombe)
chr14_+_66043877 0.330 NM_001024218
NM_020806
GPHN

gephyrin

chr14_+_75058591 0.330 BATF
basic leucine zipper transcription factor, ATF-like
chr2_+_215885063 0.329 ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr19_+_18069596 0.328 NM_015016
MAST3
microtubule associated serine/threonine kinase 3
chr3_+_39484073 0.325 NM_182935
MOBP
myelin-associated oligodendrocyte basic protein
chr4_-_151990061 0.324 LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr4_-_71751205 0.321 NM_144646
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chrX_+_52255534 0.320 NM_001097597
NM_001097598
NM_001097604
NM_001097605
NM_001097592
NM_001097593
NM_001097594
NM_001097596
NM_020411
NM_133430
XAGE1C

XAGE1E

XAGE1A

XAGE1B

XAGE1D

X antigen family, member 1C

X antigen family, member 1E

X antigen family, member 1A

X antigen family, member 1B

X antigen family, member 1D

chr19_-_19704766 0.319 NM_021030
ZNF14
zinc finger protein 14
chrX_+_52797004 0.319 NM_003147
NM_175698
NM_001164417
SSX2

SSX2B
synovial sarcoma, X breakpoint 2

synovial sarcoma, X breakpoint 2B
chrX_+_52528485 0.319 NM_001097597
NM_001097598
NM_001097604
NM_001097605
NM_001097592
NM_001097593
NM_001097594
NM_001097596
NM_020411
NM_133430
XAGE1C

XAGE1E

XAGE1A

XAGE1B

XAGE1D

X antigen family, member 1C

X antigen family, member 1E

X antigen family, member 1A

X antigen family, member 1B

X antigen family, member 1D

chr3_-_106903734 0.318 CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chrX_-_52276878 0.317 NM_001097598
NM_001097597
NM_001097605
NM_001097604
NM_001097593
NM_001097592
NM_001097596
NM_001097594
NM_133430
NM_020411
XAGE1C

XAGE1E

XAGE1A

XAGE1B

XAGE1D

X antigen family, member 1C

X antigen family, member 1E

X antigen family, member 1A

X antigen family, member 1B

X antigen family, member 1D

chr19_-_50925966 0.317 NM_001080469
FBXO46
F-box protein 46
chr4_+_54790020 0.317 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr1_+_196874839 0.316 PTPRC
protein tyrosine phosphatase, receptor type, C
chr11_-_67207112 0.315 RPL37
ribosomal protein L37
chr1_+_45577928 0.313 NM_025077
TOE1
target of EGR1, member 1 (nuclear)
chr11_-_33847834 0.310 LMO2
LIM domain only 2 (rhombotin-like 1)
chr11_-_127962662 0.308 NM_001143820
ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr2_-_175170674 0.306 WIPF1
WAS/WASL interacting protein family, member 1
chr15_+_76228733 0.306 NM_005530
IDH3A
isocitrate dehydrogenase 3 (NAD+) alpha
chr6_-_32892705 0.306 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr1_+_179269183 0.304 NM_001194999
NM_001195000
NM_001195035
NM_001531
MR1



major histocompatibility complex, class I-related



chr16_+_29734785 0.303 C16orf53
chromosome 16 open reading frame 53
chrX_+_123062143 0.303 STAG2
stromal antigen 2
chr11_-_16953135 0.302 RPL36A
ribosomal protein L36a
chr1_+_246087230 0.301 TRIM58
tripartite motif containing 58
chr16_+_31446703 0.300 NM_016633
AHSP
alpha hemoglobin stabilizing protein
chr10_+_35524060 0.296 NM_182717
NM_182718
NM_182719
NM_182720
CREM



cAMP responsive element modulator



chr12_+_52696908 0.294 NM_014620
NM_153693
HOXC4
HOXC6
homeobox C4
homeobox C6
chr15_-_35179650 0.293 NM_170674
NM_170675
NM_170676
NM_170677
MEIS2



Meis homeobox 2



chr21_+_29322100 0.293 USP16
ubiquitin specific peptidase 16
chr10_+_16518947 0.292 NM_001001484
NM_030664
PTER

phosphotriesterase related

chr7_+_116447527 0.292 ST7
suppression of tumorigenicity 7
chr16_-_85908448 0.291 NM_001195124
NM_001195125
LOC100506581

hypothetical LOC100506581

chr11_-_117718532 0.290 NM_000732
NM_001040651
CD3D

CD3d molecule, delta (CD3-TCR complex)

chr1_+_246087104 0.289 NM_015431
TRIM58
tripartite motif containing 58
chrX_+_101388810 0.288 NM_022053
NXF2
nuclear RNA export factor 2
chr3_+_152970904 0.286 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr16_-_68349445 0.286


chr1_+_111217314 0.285 CD53
CD53 molecule
chr15_+_53398424 0.285 NM_004855
PIGB
phosphatidylinositol glycan anchor biosynthesis, class B
chr5_+_69381105 0.285 NM_000344
NM_022874
NM_017411
NM_022875
NM_022876
NM_022877
SMN1

SMN2



survival of motor neuron 1, telomeric

survival of motor neuron 2, centromeric



chr1_+_240078655 0.285 NM_003686
NM_006027
EXO1

exonuclease 1

chr1_-_158883666 0.283 NM_003037
SLAMF1
signaling lymphocytic activation molecule family member 1
chr3_-_137395966 0.283 NM_001145417
MSL2
male-specific lethal 2 homolog (Drosophila)
chr9_+_130620540 0.282 NM_004435
ENDOG
endonuclease G
chr4_-_105635499 0.282 CXXC4
CXXC finger protein 4
chr2_+_86280066 0.281 NM_016622
NM_145644
MRPL35

mitochondrial ribosomal protein L35

chr9_+_127002630 0.280 NM_001174152
NM_001174153
RABEPK

Rab9 effector protein with kelch motifs

chr12_-_99060771 0.279 NM_001006947
NM_015054
UHRF1BP1L

UHRF1 binding protein 1-like

chr15_+_49760841 0.278 NM_001165257
NM_013243
SCG3

secretogranin III

chr6_-_133126278 0.278 NM_078488
VNN2
vanin 2
chr10_+_11087280 0.278 CELF2
CUGBP, Elav-like family member 2
chr16_+_2807228 0.278 PRSS21
protease, serine, 21 (testisin)
chr6_-_150099352 0.278 NUP43
nucleoporin 43kDa
chr2_+_96365233 0.275 NCAPH
non-SMC condensin I complex, subunit H
chr12_-_101398470 0.274 IGF1
insulin-like growth factor 1 (somatomedin C)
chr7_+_64476167 0.274 NM_007139
NM_152626
ZNF92

zinc finger protein 92

chr12_-_23995220 0.273 SOX5
SRY (sex determining region Y)-box 5
chr13_-_40735619 0.273 NM_004294
MTRF1
mitochondrial translational release factor 1
chr1_+_207944807 0.273 NM_005525
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.24 3.87e-02 GO:0010467 gene expression

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.15 1.11e-04 GO:0005634 nucleus
1.25 1.48e-04 GO:0031974 membrane-enclosed lumen
1.25 1.48e-04 GO:0043233 organelle lumen
1.26 1.86e-04 GO:0044428 nuclear part
1.28 3.09e-04 GO:0031981 nuclear lumen
1.24 3.50e-04 GO:0070013 intracellular organelle lumen
1.29 7.51e-03 GO:0005739 mitochondrion
1.44 1.40e-02 GO:0005694 chromosome
1.08 1.80e-02 GO:0043231 intracellular membrane-bounded organelle
1.07 1.97e-02 GO:0043227 membrane-bounded organelle
1.27 2.00e-02 GO:0005654 nucleoplasm

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.18 6.34e-03 GO:0003676 nucleic acid binding