Motif ID: HBP1_HMGB_SSRP1_UBTF.p2

Z-value: 2.152


Transcription factors associated with HBP1_HMGB_SSRP1_UBTF.p2:

Gene SymbolEntrez IDGene Name
HBP1 26959 HMG-box transcription factor 1
HMGB2 3148 high-mobility group box 2
HMGB3 3149 high-mobility group box 3
SSRP1 6749 structure specific recognition protein 1
UBTF 7343 upstream binding transcription factor, RNA polymerase I

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HBP1chr7_+_1065966410.758.6e-04Click!
SSRP1chr11_-_56859900-0.665.8e-03Click!
UBTFchr17_-_39653754,
chr17_-_39651189		-0.611.3e-02Click!
HMGB3chrX_+_149902415-0.332.1e-01Click!
HMGB2chr4_-_1744912700.107.1e-01Click!


Activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2.

activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2


Sorted Z-values histogram for motif HBP1_HMGB_SSRP1_UBTF.p2

Sorted Z-values for motif HBP1_HMGB_SSRP1_UBTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HBP1_HMGB_SSRP1_UBTF.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_111119846 8.684 NM_001142483
 C5orf13
chromosome 5 open reading frame 13
chr7_+_134114957 6.714 CALD1
caldesmon 1
chr7_+_102340579 6.577 NM_001031692
NM_005824
 LRRC17

leucine rich repeat containing 17

chr10_+_63331018 5.871 NM_032199
 ARID5B
AT rich interactive domain 5B (MRF1-like)
chr6_+_12398514 5.424 NM_001168319
NM_001955
 EDN1

endothelin 1

chr3_-_116272911 5.370 NM_001164343
 ZBTB20
zinc finger and BTB domain containing 20
chr11_+_112337199 5.278 NM_000615
NM_001076682
NM_181351
 NCAM1


neural cell adhesion molecule 1


chr6_+_114285209 4.901 NM_002356
 MARCKS
myristoylated alanine-rich protein kinase C substrate
chr1_-_191422346 4.701 NM_003783
 B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr4_-_187114407 4.588 SORBS2
sorbin and SH3 domain containing 2
chr10_+_70517863 4.380 SRGN
serglycin
chr10_+_70517823 4.219 NM_002727
 SRGN
serglycin
chr8_+_70567581 4.214 NM_001128205
NM_001128206
 SULF1

sulfatase 1

chr1_+_85819004 4.118 NM_001554
 CYR61
cysteine-rich, angiogenic inducer, 61
chr7_-_27186400 3.938 NM_153715
 HOXA10
homeobox A10
chr8_+_70567634 3.899 SULF1
sulfatase 1
chr13_-_109757442 3.836 NM_001845
 COL4A1
collagen, type IV, alpha 1
chr5_-_121441910 3.812 NM_002317
 LOX
lysyl oxidase
chr7_-_47588160 3.628 TNS3
tensin 3
chr7_-_47588266 3.559 TNS3
tensin 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 48 entries
enrichment   p-value GO term description
3.32 2.59e-02 GO:0010594 regulation of endothelial cell migration
3.03 6.45e-04 GO:0051271 negative regulation of cellular component movement
2.98 2.70e-03 GO:0030336 negative regulation of cell migration
2.98 2.70e-03 GO:2000146 negative regulation of cell motility
2.73 9.11e-03 GO:0040013 negative regulation of locomotion
2.64 3.05e-03 GO:0006469 negative regulation of protein kinase activity
2.49 1.09e-02 GO:0033673 negative regulation of kinase activity
2.34 4.14e-02 GO:0051348 negative regulation of transferase activity
2.16 1.27e-04 GO:0030334 regulation of cell migration
2.14 1.72e-04 GO:2000145 regulation of cell motility
2.13 2.01e-04 GO:0001568 blood vessel development
2.11 9.37e-05 GO:0051270 regulation of cellular component movement
2.06 3.79e-04 GO:0001944 vasculature development
2.06 5.31e-04 GO:0030029 actin filament-based process
2.05 1.27e-02 GO:0048514 blood vessel morphogenesis
2.03 8.05e-04 GO:0040012 regulation of locomotion
1.97 7.17e-03 GO:0061061 muscle structure development
1.93 2.01e-02 GO:0008361 regulation of cell size
1.87 6.99e-03 GO:0032535 regulation of cellular component size
1.78 1.07e-03 GO:0072358 cardiovascular system development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
2.79 2.65e-02 GO:0031091 platelet alpha granule
2.69 1.12e-04 GO:0030016 myofibril
2.69 7.04e-03 GO:0030027 lamellipodium
2.67 3.45e-04 GO:0044420 extracellular matrix part
2.59 6.71e-04 GO:0044449 contractile fiber part
2.59 2.29e-03 GO:0005925 focal adhesion
2.57 1.17e-03 GO:0030055 cell-substrate junction
2.52 5.19e-04 GO:0043292 contractile fiber
2.48 5.29e-03 GO:0005924 cell-substrate adherens junction
2.41 3.54e-04 GO:0005912 adherens junction
2.39 3.25e-02 GO:0030017 sarcomere
2.16 4.63e-03 GO:0070161 anchoring junction
2.00 2.60e-02 GO:0031252 cell leading edge
1.95 4.84e-04 GO:0015629 actin cytoskeleton
1.86 2.78e-02 GO:0016323 basolateral plasma membrane
1.79 2.23e-02 GO:0005578 proteinaceous extracellular matrix
1.70 2.96e-02 GO:0031012 extracellular matrix
1.65 2.05e-03 GO:0030054 cell junction
1.35 1.19e-02 GO:0005856 cytoskeleton
1.19 1.80e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
3.19 3.66e-02 GO:0008307 structural constituent of muscle
2.71 3.97e-02 GO:0005178 integrin binding
2.50 3.57e-03 GO:0019838 growth factor binding
2.23 2.15e-07 GO:0003779 actin binding
1.98 3.65e-08 GO:0008092 cytoskeletal protein binding
1.65 4.04e-04 GO:0005509 calcium ion binding
1.11 2.99e-02 GO:0005515 protein binding