Motif ID: HBP1_HMGB_SSRP1_UBTF.p2

Z-value: 2.152


Transcription factors associated with HBP1_HMGB_SSRP1_UBTF.p2:

Gene SymbolEntrez IDGene Name
HBP1 26959 HMG-box transcription factor 1
HMGB2 3148 high-mobility group box 2
HMGB3 3149 high-mobility group box 3
SSRP1 6749 structure specific recognition protein 1
UBTF 7343 upstream binding transcription factor, RNA polymerase I

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HBP1chr7_+_1065966410.758.6e-04Click!
SSRP1chr11_-_56859900-0.665.8e-03Click!
UBTFchr17_-_39653754,
chr17_-_39651189
-0.611.3e-02Click!
HMGB3chrX_+_149902415-0.332.1e-01Click!
HMGB2chr4_-_1744912700.107.1e-01Click!


Activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2.

activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2


Sorted Z-values histogram for motif HBP1_HMGB_SSRP1_UBTF.p2

Sorted Z-values for motif HBP1_HMGB_SSRP1_UBTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HBP1_HMGB_SSRP1_UBTF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_111119846 8.684 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr7_+_134114957 6.714 CALD1
caldesmon 1
chr7_+_102340579 6.577 NM_001031692
NM_005824
LRRC17

leucine rich repeat containing 17

chr10_+_63331018 5.871 NM_032199
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr6_+_12398514 5.424 NM_001168319
NM_001955
EDN1

endothelin 1

chr3_-_116272911 5.370 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr11_+_112337199 5.278 NM_000615
NM_001076682
NM_181351
NCAM1


neural cell adhesion molecule 1


chr6_+_114285209 4.901 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr1_-_191422346 4.701 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr4_-_187114407 4.588 SORBS2
sorbin and SH3 domain containing 2
chr10_+_70517863 4.380 SRGN
serglycin
chr10_+_70517823 4.219 NM_002727
SRGN
serglycin
chr8_+_70567581 4.214 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr1_+_85819004 4.118 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr7_-_27186400 3.938 NM_153715
HOXA10
homeobox A10
chr8_+_70567634 3.899 SULF1
sulfatase 1
chr13_-_109757442 3.836 NM_001845
COL4A1
collagen, type IV, alpha 1
chr5_-_121441910 3.812 NM_002317
LOX
lysyl oxidase
chr7_-_47588160 3.628 TNS3
tensin 3
chr7_-_47588266 3.559 TNS3
tensin 3
chr3_-_115825742 3.528 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr3_-_115960807 3.521 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chrX_-_99778340 3.502 NM_003270
TSPAN6
tetraspanin 6
chr4_-_186814852 3.443 SORBS2
sorbin and SH3 domain containing 2
chr4_-_111777651 3.384 PITX2
paired-like homeodomain 2
chr1_-_85816520 3.360 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr1_-_85703198 3.320 DDAH1
dimethylarginine dimethylaminohydrolase 1
chr2_-_175578156 3.319 NM_001025201
NM_001822
CHN1

chimerin (chimaerin) 1

chr4_-_186969041 3.275 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr2_-_215967442 3.159 FN1
fibronectin 1
chr6_+_148705421 3.106 NM_015278
SASH1
SAM and SH3 domain containing 1
chr7_-_27171673 3.028 NM_152739
HOXA9
homeobox A9
chrX_+_135079461 2.949 NM_001167819
FHL1
four and a half LIM domains 1
chr14_-_88953059 2.807 NM_005197
FOXN3
forkhead box N3
chr4_+_146623405 2.800 NM_001003688
SMAD1
SMAD family member 1
chr4_+_78297356 2.785 NM_004354
CCNG2
cyclin G2
chr6_-_128883125 2.755 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr6_+_89847019 2.689 NM_006813
PNRC1
proline-rich nuclear receptor coactivator 1
chr2_-_152299229 2.647 NM_001164507
NM_001164508
NM_004543
NEB


nebulin


chrX_+_135079120 2.642 NM_001159704
FHL1
four and a half LIM domains 1
chr6_+_89847183 2.627 PNRC1
proline-rich nuclear receptor coactivator 1
chr21_-_27261276 2.620 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr11_+_19328846 2.618 NM_001111018
NAV2
neuron navigator 2
chrX_-_13745108 2.611 GPM6B
glycoprotein M6B
chr7_-_47588652 2.515 TNS3
tensin 3
chr6_-_11340887 2.514 NM_006403
NM_182966
NEDD9

neural precursor cell expressed, developmentally down-regulated 9

chr5_-_39461054 2.510 NM_001343
DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr4_-_186969202 2.505 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chrX_-_13744933 2.498 GPM6B
glycoprotein M6B
chr1_+_81544432 2.490 LPHN2
latrophilin 2
chr5_-_39460687 2.437 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr7_+_134226690 2.432 NM_033139
NM_033140
CALD1

caldesmon 1

chr2_+_189547377 2.428 COL3A1
collagen, type III, alpha 1
chr7_+_93388951 2.416 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr18_+_71051713 2.403 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr5_+_15553288 2.361 NM_012304
FBXL7
F-box and leucine-rich repeat protein 7
chr2_-_190635566 2.360 NM_005259
MSTN
myostatin
chr4_-_111777584 2.347 PITX2
paired-like homeodomain 2
chr2_-_162808123 2.326 NM_004460
FAP
fibroblast activation protein, alpha
chr12_+_13240987 2.316 EMP1
epithelial membrane protein 1
chr7_+_134114912 2.306 CALD1
caldesmon 1
chr4_-_101658094 2.223 NM_001159694
NM_016242
EMCN

endomucin

chr9_-_14303899 2.187 NFIB
nuclear factor I/B
chr9_-_14304036 2.170 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr8_-_18710575 2.168 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr4_-_186815116 2.167 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr5_-_16989371 2.144 NM_012334
MYO10
myosin X
chr12_-_90029672 2.142 NM_002345
LUM
lumican
chr2_+_69093641 2.134 NM_018153
NM_032208
NM_053034
ANTXR1


anthrax toxin receptor 1


chr7_-_47545717 2.133 NM_022748
TNS3
tensin 3
chr1_-_199742871 2.122 NM_001193570
NM_004078
CSRP1

cysteine and glycine-rich protein 1

chr1_-_95165089 2.121 NM_001839
CNN3
calponin 3, acidic
chr6_-_11340869 2.105 NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr7_+_134114701 2.082 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr5_-_111340421 2.058 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr3_-_101077605 2.048 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr5_-_121441805 2.041 LOX
lysyl oxidase
chr9_+_115382760 2.037 NM_021106
RGS3
regulator of G-protein signaling 3
chr4_+_78297418 2.036 CCNG2
cyclin G2
chr12_-_90029328 2.022 LUM
lumican
chr5_-_121441866 2.008 LOX
lysyl oxidase
chr5_-_168204430 2.006


chr6_+_148705646 2.004 SASH1
SAM and SH3 domain containing 1
chr9_+_115382990 2.004 RGS3
regulator of G-protein signaling 3
chr1_-_199742841 1.998 CSRP1
cysteine and glycine-rich protein 1
chr7_-_27171648 1.978 HOXA9
homeobox A9
chr7_+_94135384 1.962 PEG10
paternally expressed 10
chr1_+_242283129 1.902 NM_006352
ZNF238
zinc finger protein 238
chr17_-_59817654 1.893 PECAM1
platelet/endothelial cell adhesion molecule
chr13_-_32678142 1.883 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr6_+_148705817 1.878 SASH1
SAM and SH3 domain containing 1
chr9_+_36026900 1.828 NM_021111
RECK
reversion-inducing-cysteine-rich protein with kazal motifs
chr1_-_199742864 1.826 CSRP1
cysteine and glycine-rich protein 1
chr3_-_55496607 1.813 WNT5A
wingless-type MMTV integration site family, member 5A
chr17_-_59817456 1.788 PECAM1
platelet/endothelial cell adhesion molecule
chr7_-_27190882 1.783 HOXA11
homeobox A11
chr9_+_115303527 1.782 NM_130795
RGS3
regulator of G-protein signaling 3
chr3_+_156280338 1.777 NM_007287
MME
membrane metallo-endopeptidase
chr7_+_134226727 1.765 CALD1
caldesmon 1
chr3_+_156280129 1.764 NM_000902
MME
membrane metallo-endopeptidase
chr2_+_36436873 1.751 NM_016441
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr5_+_86599350 1.748 RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr3_-_150903749 1.713 NM_001168278
WWTR1
WW domain containing transcription regulator 1
chr17_-_59817722 1.683 NM_000442
PECAM1
platelet/endothelial cell adhesion molecule
chr5_-_39460787 1.664 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr1_-_199742589 1.657 NM_001193571
CSRP1
cysteine and glycine-rich protein 1
chr5_-_83052606 1.652 NM_001884
HAPLN1
hyaluronan and proteoglycan link protein 1
chr2_-_188021117 1.644 NM_005795
CALCRL
calcitonin receptor-like
chr7_+_115952279 1.640 NM_001172895
CAV1
caveolin 1, caveolae protein, 22kDa
chr3_-_55496370 1.632 NM_003392
WNT5A
wingless-type MMTV integration site family, member 5A
chr2_-_151052391 1.626 NM_005168
RND3
Rho family GTPase 3
chr12_-_16649211 1.622 LMO3
LIM domain only 3 (rhombotin-like 2)
chr9_-_14303509 1.621 NFIB
nuclear factor I/B
chr11_+_20001130 1.616 NM_001111019
NAV2
neuron navigator 2
chr7_-_111633620 1.613 NM_014705
DOCK4
dedicator of cytokinesis 4
chr14_-_51605487 1.606 NID2
nidogen 2 (osteonidogen)
chr4_+_91035025 1.600 NM_007351
MMRN1
multimerin 1
chr1_-_56817823 1.599 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr1_+_99884018 1.585 NM_017734
PALMD
palmdelphin
chr3_-_151171576 1.581 PFN2
profilin 2
chr3_-_101316038 1.568 NM_001042459
NM_182909
FILIP1L

filamin A interacting protein 1-like

chr12_-_6103945 1.562 NM_000552
VWF
von Willebrand factor
chr1_+_154120170 1.557 SYT11
synaptotagmin XI
chr2_-_210876560 1.554 NM_079422
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr9_-_23816062 1.531 NM_004432
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr2_-_86418143 1.519 NM_001164731
NM_001164732
NM_022912
REEP1


receptor accessory protein 1


chr7_+_115952325 1.512 CAV1
caveolin 1, caveolae protein, 22kDa
chr10_-_91092410 1.511 LIPA
lipase A, lysosomal acid, cholesterol esterase
chrX_-_100801472 1.497 NM_014782
NM_177949
ARMCX2

armadillo repeat containing, X-linked 2

chr7_-_107430566 1.497 NM_002291
LAMB1
laminin, beta 1
chr17_-_59817575 1.487 PECAM1
platelet/endothelial cell adhesion molecule
chr16_+_31391998 1.483 NM_015927
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr3_+_160269734 1.467 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr4_-_40631397 1.466 APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr17_-_10393664 1.452 NM_001100112
NM_017534
MYH2

myosin, heavy chain 2, skeletal muscle, adult

chr15_+_22751162 1.442 NM_003097
NM_022804
NM_005678
SNRPN
SNURF

small nuclear ribonucleoprotein polypeptide N
SNRPN upstream reading frame

chr3_-_147361912 1.429 NM_000935
NM_182943
PLOD2

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

chr16_+_64958025 1.406 NM_001795
CDH5
cadherin 5, type 2 (vascular endothelium)
chr14_-_51605461 1.406 NID2
nidogen 2 (osteonidogen)
chr9_-_74735669 1.405 ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr1_+_149299490 1.401 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr3_-_124822113 1.400 NM_053031
NM_053032
MYLK

myosin light chain kinase

chrX_-_13745234 1.399 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr1_-_95165037 1.384 CNN3
calponin 3, acidic
chr14_-_91483325 1.383 FBLN5
fibulin 5
chrX_+_114701432 1.378 NM_005032
PLS3
plastin 3
chr12_+_13240868 1.374 NM_001423
EMP1
epithelial membrane protein 1
chrX_-_10605726 1.363 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr16_+_54072969 1.362 NM_001127891
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr2_-_39517633 1.362 NM_003618
MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr1_-_56817568 1.361 PPAP2B
phosphatidic acid phosphatase type 2B
chr2_+_101874765 1.361 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr2_+_101874809 1.360 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr9_-_16717887 1.358 BNC2
basonuclin 2
chr14_-_91483757 1.356 NM_006329
FBLN5
fibulin 5
chr21_+_34112456 1.354 ITSN1
intersectin 1 (SH3 domain protein)
chr14_-_51605515 1.353 NID2
nidogen 2 (osteonidogen)
chr4_+_40953652 1.349 NM_004181
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr7_+_94130752 1.344 PEG10
paternally expressed 10
chr1_+_161305188 1.339 NM_005613
RGS4
regulator of G-protein signaling 4
chr3_+_62280435 1.335 NM_020685
C3orf14
chromosome 3 open reading frame 14
chr7_-_130891861 1.334 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr4_+_40953666 1.331 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr5_-_39430180 1.329 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr18_-_51406359 1.324 TCF4
transcription factor 4
chr11_+_112337299 1.322 NCAM1
neural cell adhesion molecule 1
chr11_+_112337411 1.319 NCAM1
neural cell adhesion molecule 1
chr6_-_134540666 1.319 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr5_+_140719773 1.318 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr1_+_84402962 1.315 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr9_-_36390817 1.314 NM_194328
NM_194332
RNF38

ring finger protein 38

chr12_+_69046241 1.311 NM_014505
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr3_-_124821868 1.309 MYLK
myosin light chain kinase
chr22_+_36422940 1.305 NM_001039141
TRIOBP
TRIO and F-actin binding protein
chr5_+_135392482 1.301 NM_000358
TGFBI
transforming growth factor, beta-induced, 68kDa
chr3_-_188936941 1.300 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr13_-_32658215 1.300 NM_178007
STARD13
StAR-related lipid transfer (START) domain containing 13
chr2_-_218551786 1.294 TNS1
tensin 1
chr5_-_111120817 1.294 NM_004772
C5orf13
chromosome 5 open reading frame 13
chr10_+_31650069 1.290 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr4_+_41395493 1.288 LIMCH1
LIM and calponin homology domains 1
chr15_-_21483457 1.287 NDN
necdin homolog (mouse)
chr20_+_19818209 1.285 NM_018993
RIN2
Ras and Rab interactor 2
chr12_-_109842736 1.281 NM_000432
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr4_-_111777956 1.280 NM_153426
NM_153427
PITX2

paired-like homeodomain 2

chr9_-_36390212 1.279 NM_022781
NM_194329
RNF38

ring finger protein 38

chr1_-_56817802 1.278 PPAP2B
phosphatidic acid phosphatase type 2B
chrX_+_51944658 1.277 NM_001098800
NM_030801
NM_177535
NM_177537
MAGED4
MAGED4B


melanoma antigen family D, 4
melanoma antigen family D, 4B


chr3_+_189425886 1.277 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr17_-_45617899 1.268 COL1A1
collagen, type I, alpha 1
chr1_-_56817717 1.267 PPAP2B
phosphatidic acid phosphatase type 2B
chr17_+_16886491 1.258 NM_015134
NM_201274
MPRIP

myosin phosphatase Rho interacting protein

chrX_+_55951280 1.255


chrX_+_100220491 1.236 NM_021637
TMEM35
transmembrane protein 35
chr8_-_82557956 1.236 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr3_+_35697432 1.227 NM_198399
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr13_+_97593469 1.219 FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr22_+_36928972 1.214 NM_001161573
MAFF
v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr15_-_53996597 1.211 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr17_-_10265991 1.209 NM_002472
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.33 7.60e-07 GO:0007275 multicellular organismal development
1.30 8.65e-07 GO:0032502 developmental process
1.38 9.76e-06 GO:0048519 negative regulation of biological process
1.23 1.67e-05 GO:0032501 multicellular organismal process
1.49 2.01e-05 GO:0009653 anatomical structure morphogenesis
1.30 3.91e-05 GO:0048856 anatomical structure development
1.38 5.34e-05 GO:0048523 negative regulation of cellular process
2.11 9.37e-05 GO:0051270 regulation of cellular component movement
1.71 1.23e-04 GO:0007167 enzyme linked receptor protein signaling pathway
2.16 1.27e-04 GO:0030334 regulation of cell migration
1.31 1.59e-04 GO:0048731 system development
1.63 1.67e-04 GO:0051128 regulation of cellular component organization
2.14 1.72e-04 GO:2000145 regulation of cell motility
2.13 2.01e-04 GO:0001568 blood vessel development
2.06 3.79e-04 GO:0001944 vasculature development
1.65 4.77e-04 GO:0007155 cell adhesion
1.65 4.77e-04 GO:0022610 biological adhesion
2.06 5.31e-04 GO:0030029 actin filament-based process
3.03 6.45e-04 GO:0051271 negative regulation of cellular component movement
2.03 8.05e-04 GO:0040012 regulation of locomotion
1.37 8.57e-04 GO:0030154 cell differentiation
1.36 9.64e-04 GO:0048869 cellular developmental process
1.78 1.07e-03 GO:0072358 cardiovascular system development
1.78 1.07e-03 GO:0072359 circulatory system development
1.43 1.85e-03 GO:0009966 regulation of signal transduction
1.42 2.03e-03 GO:0007399 nervous system development
2.98 2.70e-03 GO:0030336 negative regulation of cell migration
2.98 2.70e-03 GO:2000146 negative regulation of cell motility
2.64 3.05e-03 GO:0006469 negative regulation of protein kinase activity
1.76 5.95e-03 GO:0048646 anatomical structure formation involved in morphogenesis
1.87 6.99e-03 GO:0032535 regulation of cellular component size
1.97 7.17e-03 GO:0061061 muscle structure development
1.57 7.50e-03 GO:2000026 regulation of multicellular organismal development
2.73 9.11e-03 GO:0040013 negative regulation of locomotion
1.51 1.02e-02 GO:0022008 neurogenesis
1.37 1.08e-02 GO:0023051 regulation of signaling
2.49 1.09e-02 GO:0033673 negative regulation of kinase activity
2.05 1.27e-02 GO:0048514 blood vessel morphogenesis
1.93 2.01e-02 GO:0008361 regulation of cell size
1.27 2.31e-02 GO:0048522 positive regulation of cellular process
3.32 2.59e-02 GO:0010594 regulation of endothelial cell migration
1.64 2.64e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.25 2.94e-02 GO:0048518 positive regulation of biological process
1.76 2.94e-02 GO:0090066 regulation of anatomical structure size
1.21 3.09e-02 GO:0023052 signaling
2.34 4.14e-02 GO:0051348 negative regulation of transferase activity
1.58 4.23e-02 GO:0032989 cellular component morphogenesis
1.13 4.80e-02 GO:0050794 regulation of cellular process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.69 1.12e-04 GO:0030016 myofibril
2.67 3.45e-04 GO:0044420 extracellular matrix part
2.41 3.54e-04 GO:0005912 adherens junction
1.95 4.84e-04 GO:0015629 actin cytoskeleton
2.52 5.19e-04 GO:0043292 contractile fiber
2.59 6.71e-04 GO:0044449 contractile fiber part
2.57 1.17e-03 GO:0030055 cell-substrate junction
1.65 2.05e-03 GO:0030054 cell junction
2.59 2.29e-03 GO:0005925 focal adhesion
2.16 4.63e-03 GO:0070161 anchoring junction
2.48 5.29e-03 GO:0005924 cell-substrate adherens junction
2.69 7.04e-03 GO:0030027 lamellipodium
1.35 1.19e-02 GO:0005856 cytoskeleton
1.19 1.80e-02 GO:0005886 plasma membrane
1.79 2.23e-02 GO:0005578 proteinaceous extracellular matrix
2.00 2.60e-02 GO:0031252 cell leading edge
2.79 2.65e-02 GO:0031091 platelet alpha granule
1.86 2.78e-02 GO:0016323 basolateral plasma membrane
1.70 2.96e-02 GO:0031012 extracellular matrix
1.18 3.09e-02 GO:0071944 cell periphery
2.39 3.25e-02 GO:0030017 sarcomere

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.98 3.65e-08 GO:0008092 cytoskeletal protein binding
2.23 2.15e-07 GO:0003779 actin binding
1.65 4.04e-04 GO:0005509 calcium ion binding
2.50 3.57e-03 GO:0019838 growth factor binding
1.11 2.99e-02 GO:0005515 protein binding
3.19 3.66e-02 GO:0008307 structural constituent of muscle
2.71 3.97e-02 GO:0005178 integrin binding