Motif ID: ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Z-value: 2.762


Transcription factors associated with ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2:

Gene SymbolEntrez IDGene Name
ARNT 405 aryl hydrocarbon receptor nuclear translocator
ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2
BHLHB2 8553 basic helix-loop-helix domain containing, class B, 2
MAX 4149 MYC associated factor X
MYC 4609 v-myc myelocytomatosis viral oncogene homolog (avian)
USF1 7391 upstream transcription factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAXchr14_-_646389740.783.9e-04Click!
ARNTchr1_-_1491158350.601.5e-02Click!
MYCchr8_+_1288176580.572.0e-02Click!
BHLHE40chr3_+_4996096-0.401.3e-01Click!
ARNT2chr15_+_78483624-0.341.9e-01Click!


Activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2.

activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2


Sorted Z-values histogram for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Sorted Z-values for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_56432375 9.525 CDK4
cyclin-dependent kinase 4
chr11_+_66915997 8.785 NM_004584
RAD9A
RAD9 homolog A (S. pombe)
chr12_-_56432292 8.773 CDK4
cyclin-dependent kinase 4
chr16_+_2510323 8.585 NM_001145815
NM_015944
AMDHD2

amidohydrolase domain containing 2

chr12_-_56432377 8.485 CDK4
cyclin-dependent kinase 4
chr12_-_56432385 7.895 NM_000075
CDK4
cyclin-dependent kinase 4
chrX_+_102356659 7.146 NM_001080425
NM_001127688
BEX4

brain expressed, X-linked 4

chr18_+_9698299 7.117 RAB31
RAB31, member RAS oncogene family
chr4_-_103485600 6.709 NM_001135146
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chrX_-_100490612 6.256 NM_004085
TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr11_-_85457736 6.147 PICALM
phosphatidylinositol binding clathrin assembly protein
chr1_-_26105477 5.957 NM_001145454
NM_005563
STMN1

stathmin 1

chr11_-_85457753 5.725 NM_001008660
NM_007166
PICALM

phosphatidylinositol binding clathrin assembly protein

chr18_+_9698269 5.479 RAB31
RAB31, member RAS oncogene family
chr1_+_44213229 5.415 ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr1_+_44213260 5.326 ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr6_-_31871394 5.325 VARS
valyl-tRNA synthetase
chr1_+_44213200 5.212 ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chrX_+_49075036 5.031 NM_012196
NM_001127200
NM_001098412
GAGE8
GAGE2C
GAGE2E
GAGE13
GAGE2A
G antigen 8
G antigen 2C
G antigen 2E
G antigen 13
G antigen 2A
chr7_+_106472243 5.013 NM_002736
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 28 entries
enrichment   p-value GO term description
5.27 3.69e-04 GO:0015682 ferric iron transport
5.27 3.69e-04 GO:0033572 transferrin transport
4.64 1.66e-02 GO:0015988 energy coupled proton transport, against electrochemical gradient
4.64 1.66e-02 GO:0015991 ATP hydrolysis coupled proton transport
4.46 2.64e-02 GO:0009161 ribonucleoside monophosphate metabolic process
2.47 2.67e-02 GO:0042254 ribosome biogenesis
2.13 3.92e-02 GO:0034404 nucleobase, nucleoside and nucleotide biosynthetic process
2.13 3.92e-02 GO:0034654 nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process
2.01 3.91e-02 GO:0018130 heterocycle biosynthetic process
1.86 1.06e-02 GO:0044271 cellular nitrogen compound biosynthetic process
1.73 2.98e-03 GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
1.73 9.79e-03 GO:0006753 nucleoside phosphate metabolic process
1.73 9.79e-03 GO:0009117 nucleotide metabolic process
1.71 1.93e-03 GO:0006396 RNA processing
1.63 8.18e-03 GO:0046483 heterocycle metabolic process
1.53 1.04e-13 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.50 8.50e-09 GO:0090304 nucleic acid metabolic process
1.48 6.21e-14 GO:0034641 cellular nitrogen compound metabolic process
1.47 1.42e-05 GO:0016070 RNA metabolic process
1.46 3.50e-13 GO:0006807 nitrogen compound metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 29 entries
enrichment   p-value GO term description
8.78 1.75e-02 GO:0042719 mitochondrial intermembrane space protein transporter complex
5.93 1.55e-03 GO:0033176 proton-transporting V-type ATPase complex
5.27 5.51e-03 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
3.60 1.10e-02 GO:0016469 proton-transporting two-sector ATPase complex
2.11 7.59e-09 GO:0005730 nucleolus
2.03 6.88e-03 GO:0016604 nuclear body
1.85 5.56e-03 GO:0019866 organelle inner membrane
1.82 1.06e-04 GO:0030529 ribonucleoprotein complex
1.81 2.52e-02 GO:0005743 mitochondrial inner membrane
1.60 1.82e-03 GO:0031967 organelle envelope
1.58 8.70e-11 GO:0031981 nuclear lumen
1.58 3.38e-03 GO:0031975 envelope
1.55 1.15e-06 GO:0005654 nucleoplasm
1.55 8.23e-03 GO:0044451 nucleoplasm part
1.54 2.14e-11 GO:0044428 nuclear part
1.51 8.12e-11 GO:0070013 intracellular organelle lumen
1.50 6.28e-11 GO:0031974 membrane-enclosed lumen
1.49 3.78e-10 GO:0043233 organelle lumen
1.31 1.56e-12 GO:0005634 nucleus
1.26 9.37e-09 GO:0044446 intracellular organelle part

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.80 1.28e-07 GO:0003723 RNA binding
1.30 7.37e-05 GO:0003676 nucleic acid binding
1.12 1.00e-02 GO:0005515 protein binding