Motif ID: TP53.p2

Z-value: 1.293


Transcription factors associated with TP53.p2:

Gene SymbolEntrez IDGene Name
TP53 7157 tumor protein p53

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TP53chr17_-_75314560.572.0e-02Click!


Activity profile for motif TP53.p2.

activity profile for motif TP53.p2


Sorted Z-values histogram for motif TP53.p2

Sorted Z-values for motif TP53.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TP53.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_46593923 3.269 NM_001040084
NM_001098845
ANXA8L2
LOC653110
ANXA8
ANXA8L1
annexin A8-like 2
hypothetical LOC653110
annexin A8
annexin A8-like 1
chr10_+_47216925 2.986 NM_001630
ANXA8L2
ANXA8
annexin A8-like 2
annexin A8
chr6_+_116798791 2.351 NM_013352
DSE
dermatan sulfate epimerase
chr1_-_207892420 2.245 NM_000228
LAMB3
laminin, beta 3
chr6_+_36752244 2.167 NM_078467
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr18_+_19523526 2.117 NM_001127717
NM_198129
LAMA3

laminin, alpha 3

chr18_-_26876622 2.059 NM_001941
NM_024423
DSC3

desmocollin 3

chr18_+_55718171 1.833 NM_021127
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr15_-_50608296 1.636 NM_000259
NM_001142495
MYO5A

myosin VA (heavy chain 12, myoxin)

chr5_+_17270474 1.571 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr19_-_6542012 1.570 CD70
CD70 molecule
chr10_+_5556923 1.473 NM_005185
CALML3
calmodulin-like 3
chr4_-_9727384 1.412


chr19_-_6542082 1.190 CD70
CD70 molecule
chr10_+_90741024 1.184 FAS
Fas (TNF receptor superfamily, member 6)
chr6_-_138470160 1.180 NM_022121
PERP
PERP, TP53 apoptosis effector
chrX_+_151837064 1.128 NM_001178113
ZNF185
zinc finger protein 185 (LIM domain)
chr7_+_115953582 1.112 NM_001172896
NM_001172897
CAV1

caveolin 1, caveolae protein, 22kDa

chr13_+_35904408 0.934 NM_001111045
NM_003914
CCNA1

cyclin A1

chr2_-_24160683 0.932 TP53I3
tumor protein p53 inducible protein 3
chrX_-_154341451 0.895 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated (intronic transcript) 2
coagulation factor VIII-associated (intronic transcript) 3
coagulation factor VIII-associated (intronic transcript) 1
chrX_+_153767803 0.891 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated (intronic transcript) 2
coagulation factor VIII-associated (intronic transcript) 3
coagulation factor VIII-associated (intronic transcript) 1
chrX_+_154264931 0.856 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated (intronic transcript) 2
coagulation factor VIII-associated (intronic transcript) 3
coagulation factor VIII-associated (intronic transcript) 1
chr4_+_103641511 0.842 NM_001165412
NM_003998
NFKB1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

chr2_-_110231431 0.810 NM_005434
MALL
mal, T-cell differentiation protein-like
chr8_-_22982351 0.799 TNFRSF10B
tumor necrosis factor receptor superfamily, member 10b
chr1_+_221966835 0.791 CAPN2
calpain 2, (m/II) large subunit
chr22_-_16637194 0.748 BID
BH3 interacting domain death agonist
chr1_-_151775119 0.732 S100A6
S100 calcium binding protein A6
chr4_+_103641585 0.727 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr6_-_84197370 0.723 ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr1_-_151775087 0.719 S100A6
S100 calcium binding protein A6
chrX_+_129133234 0.718 NM_004794
RAB33A
RAB33A, member RAS oncogene family
chrX_-_153767625 0.711 NM_019863
F8
coagulation factor VIII, procoagulant component
chr4_-_9727476 0.710 WDR1
WD repeat domain 1
chr4_-_9727456 0.695 WDR1
WD repeat domain 1
chr2_-_38156811 0.690 NM_000104
CYP1B1
cytochrome P450, family 1, subfamily B, polypeptide 1
chr3_-_184363157 0.689 NM_014398
LAMP3
lysosomal-associated membrane protein 3
chr20_-_1321571 0.676 FKBP1A
FK506 binding protein 1A, 12kDa
chr7_+_65307816 0.664 TPST1
tyrosylprotein sulfotransferase 1
chr11_-_66993211 0.656 NM_001078650
NM_001078651
NM_025124
TMEM134


transmembrane protein 134


chr17_+_75849221 0.654 NM_020914
NM_020954
RNF213

ring finger protein 213

chr4_-_9727542 0.650 WDR1
WD repeat domain 1
chr7_+_43589163 0.650 NM_004760
STK17A
serine/threonine kinase 17a
chr22_-_16637221 0.647 BID
BH3 interacting domain death agonist
chr9_+_114953087 0.644 SLC31A2
solute carrier family 31 (copper transporters), member 2
chr4_-_9727394 0.642 WDR1
WD repeat domain 1
chr1_+_13782838 0.641 NM_006474
NM_198389
PDPN

podoplanin

chr8_-_22982435 0.623 NM_003842
NM_147187
TNFRSF10B

tumor necrosis factor receptor superfamily, member 10b

chr1_-_6375949 0.619 ACOT7
acyl-CoA thioesterase 7
chr22_+_36632242 0.613 NM_033386
MICALL1
MICAL-like 1
chr12_-_74710741 0.595 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr11_+_9642200 0.592 NM_015055
SWAP70
SWAP switching B-cell complex 70kDa subunit
chr16_+_56211410 0.583 NM_001145770
NM_005682
GPR56

G protein-coupled receptor 56

chr2_-_24161033 0.579 NM_147184
NM_004881
TP53I3

tumor protein p53 inducible protein 3

chr6_-_101435918 0.571 NM_006828
NM_022091
ASCC3

activating signal cointegrator 1 complex subunit 3

chr19_+_54149843 0.560 NM_004324
NM_138761
NM_138763
NM_138764
BAX



BCL2-associated X protein



chr20_-_1321702 0.558 FKBP1A-SDCBP2
FKBP1A
FKBP1A-SDCBP2 read-through transcript
FK506 binding protein 1A, 12kDa
chr19_+_54149941 0.555 BAX
BCL2-associated X protein
chr19_+_54149963 0.544 BAX
BCL2-associated X protein
chr14_-_64040072 0.539 NM_006977
ZBTB25
zinc finger and BTB domain containing 25
chr9_+_118489394 0.531 NM_001099679
NM_012210
TRIM32

tripartite motif containing 32

chr22_-_16637160 0.530 BID
BH3 interacting domain death agonist
chr7_+_48095263 0.523 NM_003364
UPP1
uridine phosphorylase 1
chr10_+_124124083 0.522 NM_001001974
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr20_-_1321744 0.517 NM_000801
NM_054014
FKBP1A

FK506 binding protein 1A, 12kDa

chr5_+_52320660 0.512 NM_002203
ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr10_+_124124196 0.512 PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr10_-_105202139 0.507 NM_015916
CALHM2
calcium homeostasis modulator 2
chr1_-_10455100 0.504 DFFA
DNA fragmentation factor, 45kDa, alpha polypeptide
chr11_-_64327197 0.503 NM_004579
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr1_+_221966849 0.501 CAPN2
calpain 2, (m/II) large subunit
chr10_-_105202012 0.500 CALHM2
calcium homeostasis modulator 2
chr2_+_95055155 0.496 NM_002371
NM_022438
NM_022439
NM_022440
MAL



mal, T-cell differentiation protein



chr4_-_9727598 0.494 NM_005112
NM_017491
WDR1

WD repeat domain 1

chrX_-_106846684 0.490 TSC22D3
TSC22 domain family, member 3
chr19_-_4768502 0.482 TICAM1
toll-like receptor adaptor molecule 1
chr4_+_148872902 0.470 NM_024605
ARHGAP10
Rho GTPase activating protein 10
chr1_-_10455190 0.465 NM_004401
NM_213566
DFFA

DNA fragmentation factor, 45kDa, alpha polypeptide

chr2_-_26058831 0.464 KIF3C
kinesin family member 3C
chr5_+_121675284 0.457 SNCAIP
synuclein, alpha interacting protein
chr1_-_207892296 0.457 NM_001127641
LAMB3
laminin, beta 3
chr7_+_48094750 0.455 NM_181597
UPP1
uridine phosphorylase 1
chr18_-_32662690 0.455 C18orf10
chromosome 18 open reading frame 10
chr14_+_64040979 0.454 NM_001123329
NM_014950
ZBTB1

zinc finger and BTB domain containing 1

chr10_-_95231933 0.448 NM_013451
NM_133337
MYOF

myoferlin

chr2_-_26058941 0.446 NM_002254
KIF3C
kinesin family member 3C
chr16_-_15057328 0.440 NM_173474
NTAN1
N-terminal asparagine amidase
chr11_+_118544625 0.436 NM_024618
NM_170722
NLRX1

NLR family member X1

chr5_+_121675672 0.434 NM_005460
SNCAIP
synuclein, alpha interacting protein
chr5_-_176763991 0.429 F12
coagulation factor XII (Hageman factor)
chr1_-_149004852 0.428 CTSS
cathepsin S
chr16_+_56211150 0.424 GPR56
G protein-coupled receptor 56
chr1_-_151775221 0.424 NM_014624
S100A6
S100 calcium binding protein A6
chr19_-_47438518 0.419 GSK3A
glycogen synthase kinase 3 alpha
chr16_+_30102426 0.418 CORO1A
coronin, actin binding protein, 1A
chr6_-_30820264 0.413 NM_003897
IER3
immediate early response 3
chr8_+_94999167 0.412 NM_001161778
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr18_-_32663082 0.411 NM_015476
C18orf10
chromosome 18 open reading frame 10
chr6_-_32271277 0.402 NM_022107
GPSM3
G-protein signaling modulator 3
chr6_+_36206239 0.399 NM_002754
MAPK13
mitogen-activated protein kinase 13
chr18_-_32662942 0.392 C18orf10
chromosome 18 open reading frame 10
chr1_+_154318954 0.389 LMNA
lamin A/C
chr3_-_12775718 0.389 NM_018306
TMEM40
transmembrane protein 40
chr22_-_16637238 0.388 NM_001196
NM_197967
BID

BH3 interacting domain death agonist

chr21_+_41714311 0.386 NM_001144925
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr7_+_48095464 0.385 UPP1
uridine phosphorylase 1
chr1_-_154977526 0.383 NM_024540
NM_145729
MRPL24

mitochondrial ribosomal protein L24

chr19_-_47438548 0.382 GSK3A
glycogen synthase kinase 3 alpha
chr11_-_107969554 0.380 NM_015065
EXPH5
exophilin 5
chr18_-_32662843 0.379 C18orf10
chromosome 18 open reading frame 10
chr12_+_27377034 0.370 NM_020183
ARNTL2
aryl hydrocarbon receptor nuclear translocator-like 2
chr4_+_48683021 0.368 NM_025087
CWH43
cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
chr10_+_133850325 0.368 NM_006426
DPYSL4
dihydropyrimidinase-like 4
chr8_+_55533047 0.368 NM_022454
SOX17
SRY (sex determining region Y)-box 17
chr20_-_62151216 0.366 NM_018419
SOX18
SRY (sex determining region Y)-box 18
chr4_-_57671112 0.357 IGFBP7
insulin-like growth factor binding protein 7
chr4_-_57671307 0.351 IGFBP7
insulin-like growth factor binding protein 7
chr9_-_125732005 0.351 NM_020946
NM_024820
DENND1A

DENN/MADD domain containing 1A

chr7_+_140042932 0.348 NM_004546
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr6_+_76515608 0.346 NM_004999
MYO6
myosin VI
chr4_-_186584031 0.344 NM_018359
UFSP2
UFM1-specific peptidase 2
chr15_+_38319326 0.337 NM_020168
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr18_-_32662946 0.336 C18orf10
chromosome 18 open reading frame 10
chr1_+_41217555 0.335 NM_001905
CTPS
CTP synthase
chr19_-_47438563 0.334 NM_019884
GSK3A
glycogen synthase kinase 3 alpha
chr5_-_141041982 0.334 NM_022481
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr19_+_48772791 0.334 NM_001193621
LOC390940
hypothetical protein LOC390940
chr14_+_96333434 0.333 NM_003384
VRK1
vaccinia related kinase 1
chr12_+_22669352 0.327 ETNK1
ethanolamine kinase 1
chrX_-_106846253 0.314 NM_001015881
TSC22D3
TSC22 domain family, member 3
chr7_+_98810287 0.311 ARPC1B
actin related protein 2/3 complex, subunit 1B, 41kDa
chr4_-_57671273 0.310 NM_001553
IGFBP7
insulin-like growth factor binding protein 7
chr3_+_52504410 0.305 STAB1
stabilin 1
chr5_-_137099361 0.304 KLHL3
kelch-like 3 (Drosophila)
chr2_+_169021039 0.300 NM_203463
LASS6
LAG1 homolog, ceramide synthase 6
chr16_+_55199978 0.299 NM_005953
MT2A
metallothionein 2A
chr5_+_141328876 0.298 RNF14
ring finger protein 14
chr1_-_201202956 0.296 NM_016243
CYB5R1
cytochrome b5 reductase 1
chr3_+_52504391 0.295 NM_015136
STAB1
stabilin 1
chr3_+_16901455 0.293 NM_001144382
PLCL2
phospholipase C-like 2
chr8_-_102286695 0.292 ZNF706
zinc finger protein 706
chr19_-_47438583 0.290 GSK3A
glycogen synthase kinase 3 alpha
chr11_-_59140192 0.287 NM_002556
OSBP
oxysterol binding protein
chr8_+_95801277 0.286 NM_181787
DPY19L4
dpy-19-like 4 (C. elegans)
chr5_-_141041933 0.282 ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr11_+_63883192 0.282 NM_001006944
NM_003942
RPS6KA4

ribosomal protein S6 kinase, 90kDa, polypeptide 4

chr14_+_76856982 0.281 NM_145870
NM_145871
GSTZ1

glutathione transferase zeta 1

chr12_+_54784614 0.281 PA2G4
proliferation-associated 2G4, 38kDa
chr19_+_40298571 0.279 NM_001136007
NM_001136008
NM_001136009
NM_001136010
NM_001136011
NM_001136012
NM_005971
NM_021910
FXYD3







FXYD domain containing ion transport regulator 3







chr7_+_98810262 0.279 NM_005720
ARPC1B
actin related protein 2/3 complex, subunit 1B, 41kDa
chr1_-_149004879 0.277 CTSS
cathepsin S
chr12_+_54784591 0.273 PA2G4
proliferation-associated 2G4, 38kDa
chr10_-_30388439 0.272 NM_020848
KIAA1462
KIAA1462
chr8_+_104379836 0.271 NM_001164615
FZD6
frizzled homolog 6 (Drosophila)
chr3_+_197951203 0.270 PAK2
p21 protein (Cdc42/Rac)-activated kinase 2
chr4_+_85723080 0.270 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr4_-_55686503 0.269 NM_002253
KDR
kinase insert domain receptor (a type III receptor tyrosine kinase)
chr2_-_219826854 0.266 NM_006000
TUBA4A
tubulin, alpha 4a
chr3_+_33293915 0.266 NM_012157
NM_001171713
FBXL2

F-box and leucine-rich repeat protein 2

chr12_+_67489063 0.263 MDM2
Mdm2 p53 binding protein homolog (mouse)
chr19_+_40299058 0.258 FXYD3
FXYD domain containing ion transport regulator 3
chr10_-_104252394 0.258 NM_005736
ACTR1A
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr1_+_221966684 0.255 NM_001748
CAPN2
calpain 2, (m/II) large subunit
chr11_+_19095215 0.255 NM_001001483
NM_019028
ZDHHC13

zinc finger, DHHC-type containing 13

chr9_+_116413443 0.251 NM_153045
C9orf91
chromosome 9 open reading frame 91
chr18_-_42751305 0.247 NM_004671
NM_173206
PIAS2

protein inhibitor of activated STAT, 2

chr6_-_109882116 0.247 MICAL1
microtubule associated monoxygenase, calponin and LIM domain containing 1
chr6_-_47030492 0.240 NM_015234
GPR116
G protein-coupled receptor 116
chr3_-_44494160 0.239 NM_181489
ZNF445
zinc finger protein 445
chr10_-_101759630 0.238 NM_015221
DNMBP
dynamin binding protein
chr12_+_103375116 0.234 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr1_+_86662356 0.234 NM_006536
CLCA2
chloride channel accessory 2
chrX_+_12719443 0.233 PRPS2
phosphoribosyl pyrophosphate synthetase 2
chr6_+_76515690 0.232 MYO6
myosin VI
chr1_-_54291474 0.229 TMEM59
transmembrane protein 59
chr1_-_54291378 0.222 TMEM59
transmembrane protein 59
chr18_+_32131628 0.220 NM_025135
FHOD3
formin homology 2 domain containing 3
chr11_+_124944580 0.220 EI24
etoposide induced 2.4 mRNA
chr22_+_39096573 0.215 SGSM3
small G protein signaling modulator 3
chr21_+_42807052 0.214 SLC37A1
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr2_+_113119985 0.212 NM_005415
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr12_+_103374892 0.212 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr2_-_171998681 0.212 METTL8
methyltransferase like 8
chr19_-_1556464 0.211 NM_006830
UQCR11
ubiquinol-cytochrome c reductase, complex III subunit XI
chr8_+_94998258 0.211 NM_018444
NM_001161780
NM_001161779
NM_001161781
PDP1



pyruvate dehyrogenase phosphatase catalytic subunit 1



chr20_+_33223434 0.210 NM_006404
PROCR
protein C receptor, endothelial
chr4_-_68249442 0.209 NM_018227
UBA6
ubiquitin-like modifier activating enzyme 6
chr19_-_6432765 0.208 NM_024898
DENND1C
DENN/MADD domain containing 1C
chr11_+_64705725 0.205 NM_001198869
CAPN1
calpain 1, (mu/I) large subunit
chr7_+_65307691 0.204 NM_003596
TPST1
tyrosylprotein sulfotransferase 1
chr14_-_74148422 0.201 NM_000428
LTBP2
latent transforming growth factor beta binding protein 2
chr1_-_85286716 0.200 NM_018298
MCOLN3
mucolipin 3
chr11_-_67032125 0.200 CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr4_+_52403922 0.198 NM_001040402
NM_015115
DCUN1D4

DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)

chr9_-_94566823 0.198 NM_001003800
NM_015250
BICD2

bicaudal D homolog 2 (Drosophila)

chr19_-_2002222 0.195 NM_017572
NM_199054
MKNK2

MAP kinase interacting serine/threonine kinase 2

chr11_+_124944573 0.195 EI24
etoposide induced 2.4 mRNA
chr5_+_76150637 0.194 F2RL1
coagulation factor II (thrombin) receptor-like 1
chr19_+_3523903 0.193 NM_006339
HMG20B
high-mobility group 20B

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.