Motif ID: POU5F1.p2

Z-value: 2.037


Transcription factors associated with POU5F1.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU5F1chr6_-_312425930.224.2e-01Click!


Activity profile for motif POU5F1.p2.

activity profile for motif POU5F1.p2


Sorted Z-values histogram for motif POU5F1.p2

Sorted Z-values for motif POU5F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_64922420 10.862 NM_002758
 MAP2K6
mitogen-activated protein kinase kinase 6
chr10_+_11246934 6.958 NM_001025076
NM_001083591
 CELF2

CUGBP, Elav-like family member 2

chr10_-_98021144 6.916 NM_001114094
NM_013314
 BLNK

B-cell linker

chr4_-_91979113 5.411 NM_183049
 TMSL3
thymosin-like 3
chr22_+_21027538 4.942


chr22_+_21543671 4.814 IGLV4-3
immunoglobulin lambda variable 4-3
chr22_+_21116283 4.540


chr15_-_78050515 4.410 NM_001114735
NM_004049
 BCL2A1

BCL2-related protein A1

chr1_-_42738535 4.408 TMSB4XP1
thymosin beta 4, X-linked pseudogene 1
chr22_+_21340757 4.163


chr22_+_21370394 4.073 IGL@
immunoglobulin lambda locus
chr14_-_106249999 4.070 IGHA1
immunoglobulin heavy constant alpha 1
chr14_-_105476678 3.881 IGHM
immunoglobulin heavy constant mu
chr6_+_12825022 3.841 PHACTR1
phosphatase and actin regulator 1
chr2_+_88966170 3.824


chr22_+_21065134 3.818 LOC100290481
immunoglobulin lambda light chain-like
chr22_+_21464980 3.785


chr14_-_105997732 3.692 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr10_+_11247059 3.618 CELF2
CUGBP, Elav-like family member 2
chr4_-_71751070 3.571 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 38 entries
enrichment   p-value GO term description
7.38 2.14e-02 GO:0021602 cranial nerve morphogenesis
1.87 8.15e-03 GO:0007409 axonogenesis
1.84 8.94e-03 GO:0048812 neuron projection morphogenesis
1.80 8.71e-03 GO:0031175 neuron projection development
1.80 2.53e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.73 9.39e-03 GO:0048666 neuron development
1.67 8.60e-03 GO:0030182 neuron differentiation
1.58 2.40e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.58 5.76e-03 GO:0022008 neurogenesis
1.57 7.84e-03 GO:0006351 transcription, DNA-dependent
1.55 4.13e-02 GO:0048699 generation of neurons
1.50 3.03e-04 GO:0007399 nervous system development
1.50 3.71e-02 GO:0032774 RNA biosynthetic process
1.48 2.43e-06 GO:0006355 regulation of transcription, DNA-dependent
1.46 3.96e-06 GO:0051252 regulation of RNA metabolic process
1.45 3.61e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.42 6.30e-06 GO:0010468 regulation of gene expression
1.42 1.20e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.41 1.31e-03 GO:0048513 organ development
1.39 2.24e-03 GO:0030154 cell differentiation

Gene overrepresentation in compartment category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.21 6.71e-05 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
3.48 4.94e-02 GO:0003823 antigen binding
1.81 2.88e-08 GO:0001071 nucleic acid binding transcription factor activity
1.81 2.88e-08 GO:0003700 sequence-specific DNA binding transcription factor activity
1.74 2.55e-04 GO:0043565 sequence-specific DNA binding
1.59 2.61e-04 GO:0030528 transcription regulator activity
1.50 4.21e-08 GO:0003677 DNA binding
1.31 7.60e-05 GO:0003676 nucleic acid binding
1.06 2.76e-02 GO:0005488 binding