Motif ID: PRRX1,2.p2

Z-value: 1.306


Transcription factors associated with PRRX1,2.p2:

Gene SymbolEntrez IDGene Name
PRRX1 5396 paired related homeobox 1
PRRX2 51450 paired related homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PRRX1chr1_+_1688999360.391.4e-01Click!
PRRX2chr9_+_1314678370.253.6e-01Click!


Activity profile for motif PRRX1,2.p2.

activity profile for motif PRRX1,2.p2


Sorted Z-values histogram for motif PRRX1,2.p2

Sorted Z-values for motif PRRX1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PRRX1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_37070862 6.385 NM_001135934
NM_001135935
NM_001135936
NM_006475
 POSTN



periostin, osteoblast specific factor



chr10_-_95231933 5.336 NM_013451
NM_133337
 MYOF

myoferlin

chr12_-_90029328 4.759 LUM
lumican
chrX_+_135058402 4.717 NM_001159700
 FHL1
four and a half LIM domains 1
chr11_+_5667494 4.643 NM_006074
 TRIM22
tripartite motif containing 22
chr3_+_160269734 4.389 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
 IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr3_+_161040343 3.947 NM_001197109
 SCHIP1
schwannomin interacting protein 1
chr3_+_161040439 3.842 SCHIP1
schwannomin interacting protein 1
chr1_+_149299490 3.672 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_+_149299307 3.669 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_+_149299504 3.662 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_+_149299530 3.659 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr2_+_189547377 3.581 COL3A1
collagen, type III, alpha 1
chr12_-_90029672 3.568 NM_002345
 LUM
lumican
chr20_+_9236446 3.291 NM_000933
 PLCB4
phospholipase C, beta 4
chr2_-_190635566 3.254 NM_005259
 MSTN
myostatin
chr12_-_90100710 3.254 DCN
decorin
chr3_-_55490401 3.239 WNT5A
wingless-type MMTV integration site family, member 5A
chr1_-_103269356 3.153 COL11A1
collagen, type XI, alpha 1
chr7_-_27171648 3.121 HOXA9
homeobox A9

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
1.98 2.40e-02 GO:0007156 homophilic cell adhesion
1.69 7.87e-03 GO:0016337 cell-cell adhesion
1.50 1.70e-04 GO:0007155 cell adhesion
1.50 1.70e-04 GO:0022610 biological adhesion
1.24 4.87e-02 GO:0007166 cell surface receptor linked signaling pathway
1.19 2.52e-03 GO:0007165 signal transduction
1.16 1.08e-02 GO:0023052 signaling
1.15 1.98e-03 GO:0032501 multicellular organismal process
1.15 2.53e-02 GO:0051716 cellular response to stimulus
1.13 2.33e-03 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
1.76 1.24e-04 GO:0005578 proteinaceous extracellular matrix
1.59 3.56e-03 GO:0031012 extracellular matrix
1.36 5.31e-04 GO:0044421 extracellular region part
1.30 1.87e-05 GO:0005576 extracellular region
1.18 2.75e-04 GO:0071944 cell periphery
1.18 3.51e-04 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
2.79 1.94e-02 GO:0005518 collagen binding
1.47 7.22e-04 GO:0005509 calcium ion binding
1.28 1.28e-02 GO:0004872 receptor activity
1.27 2.32e-03 GO:0004871 signal transducer activity
1.27 2.32e-03 GO:0060089 molecular transducer activity