Motif ID: PITX1..3.p2

Z-value: 3.226


Transcription factors associated with PITX1..3.p2:

Gene SymbolEntrez IDGene Name
PITX1 5307 paired-like homeodomain 1
PITX2 5308 paired-like homeodomain 2
PITX3 5309 paired-like homeodomain 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PITX1chr5_-_1343977400.693.1e-03Click!
PITX3chr10_-_1039912190.322.3e-01Click!
PITX2chr4_-_111777651-0.282.9e-01Click!


Activity profile for motif PITX1..3.p2.

activity profile for motif PITX1..3.p2


Sorted Z-values histogram for motif PITX1..3.p2

Sorted Z-values for motif PITX1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PITX1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_92144146 6.998 NM_001195684
 TGFBR3
transforming growth factor, beta receptor III
chr15_+_26876480 5.478


chr12_-_116021473 4.607 NM_001168325
NM_017899
 TESC

tescalcin

chr19_-_9592883 4.383 NM_152289
 ZNF561
zinc finger protein 561
chr11_+_61861458 4.143 ASRGL1
asparaginase like 1
chr3_+_188222337 4.088 NM_003032
 ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr15_-_20666684 4.048 LOC283683
hypothetical LOC283683
chr16_+_29378694 3.661 NM_001017390
NM_177552
 SULT1A4
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chrX_-_129099695 3.608 NM_001130846
 AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
chr6_-_31871530 3.367 NM_006295
 VARS
valyl-tRNA synthetase
chr11_+_61861349 3.318 NM_001083926
NM_025080
 ASRGL1

asparaginase like 1

chr16_+_30118036 3.260 NM_001017390
NM_177552
 SULT1A4
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr1_+_114298021 3.185 NM_181358
 HIPK1
homeodomain interacting protein kinase 1
chr16_+_170334 3.112 NM_005331
 HBQ1
hemoglobin, theta 1
chr11_-_117718532 3.046 NM_000732
NM_001040651
 CD3D

CD3d molecule, delta (CD3-TCR complex)

chr4_+_74499651 3.029 ALB
albumin
chr6_-_44341296 2.963 NM_004556
 NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr16_+_29597829 2.830 NM_014298
 QPRT
quinolinate phosphoribosyltransferase
chr17_-_59437782 2.817 NM_000873
 ICAM2
intercellular adhesion molecule 2
chrX_-_16640590 2.771 NM_175859
NM_019857
 CTPS2

CTP synthase II


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
1.90 3.92e-02 GO:0008380 RNA splicing
1.85 1.15e-02 GO:0006397 mRNA processing
1.74 6.08e-04 GO:0006396 RNA processing
1.72 7.54e-03 GO:0016071 mRNA metabolic process
1.30 3.25e-02 GO:0090304 nucleic acid metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
5.17 2.08e-03 GO:0005689 U12-type spliceosomal complex
2.32 1.42e-02 GO:0005681 spliceosomal complex
1.62 2.25e-02 GO:0030529 ribonucleoprotein complex
1.31 3.10e-03 GO:0044428 nuclear part
1.27 1.26e-02 GO:0031974 membrane-enclosed lumen
1.27 1.43e-02 GO:0043233 organelle lumen
1.25 4.51e-02 GO:0070013 intracellular organelle lumen
1.17 1.98e-03 GO:0005634 nucleus
1.07 2.05e-02 GO:0005622 intracellular
1.07 3.56e-02 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.54 5.21e-03 GO:0003723 RNA binding
1.31 3.59e-05 GO:0003676 nucleic acid binding