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Motif ID: PITX1..3.p2

Z-value: 3.226

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_92144146	6.998	NM_001195684	TGFBR3	transforming growth factor, beta receptor III
chr15_+_26876480	5.478
chr12_-_116021473	4.607	NM_001168325 NM_017899	TESC	tescalcin
chr19_-_9592883	4.383	NM_152289	ZNF561	zinc finger protein 561
chr11_+_61861458	4.143		ASRGL1	asparaginase like 1
chr3_+_188222337	4.088	NM_003032	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr15_-_20666684	4.048		LOC283683	hypothetical LOC283683
chr16_+_29378694	3.661	NM_001017390 NM_177552	SULT1A4 SULT1A3	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chrX_-_129099695	3.608	NM_001130846	AIFM1	apoptosis-inducing factor, mitochondrion-associated, 1
chr6_-_31871530	3.367	NM_006295	VARS	valyl-tRNA synthetase
chr11_+_61861349	3.318	NM_001083926 NM_025080	ASRGL1	asparaginase like 1
chr16_+_30118036	3.260	NM_001017390 NM_177552	SULT1A4 SULT1A3	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr1_+_114298021	3.185	NM_181358	HIPK1	homeodomain interacting protein kinase 1
chr16_+_170334	3.112	NM_005331	HBQ1	hemoglobin, theta 1
chr11_-_117718532	3.046	NM_000732 NM_001040651	CD3D	CD3d molecule, delta (CD3-TCR complex)
chr4_+_74499651	3.029		ALB	albumin
chr6_-_44341296	2.963	NM_004556	NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr16_+_29597829	2.830	NM_014298	QPRT	quinolinate phosphoribosyltransferase
chr17_-_59437782	2.817	NM_000873	ICAM2	intercellular adhesion molecule 2
chrX_-_16640590	2.771	NM_175859 NM_019857	CTPS2	CTP synthase II
chr1_-_16006779	2.724	NM_001089591	UQCRHL	ubiquinol-cytochrome c reductase hinge protein-like
chr10_-_69901735	2.632	NM_001080449	DNA2	DNA replication helicase 2 homolog (yeast)
chrX_+_9391314	2.546	NM_001139466 NM_001139467 NM_001139468	TBL1X	transducin (beta)-like 1X-linked
chr17_-_59451662	2.445	NM_001099786 NM_001099787 NM_001099788 NM_001099789	ICAM2	intercellular adhesion molecule 2
chr2_+_218992053	2.417	NM_007127	VIL1	villin 1
chrX_+_138060	2.300	NM_018390	PLCXD1	phosphatidylinositol-specific phospholipase C, X domain containing 1
chrY_+_138060	2.300	NM_018390	PLCXD1	phosphatidylinositol-specific phospholipase C, X domain containing 1
chr22_+_27498679	2.246		CCDC117	coiled-coil domain containing 117
chr19_-_44518516	2.234	NM_004877	GMFG	glia maturation factor, gamma
chr19_-_13074513	2.216		LYL1	lymphoblastic leukemia derived sequence 1
chr17_-_61655915	2.196	NM_000042	APOH	apolipoprotein H (beta-2-glycoprotein I)
chr11_+_22652894	2.195	NM_005256	GAS2	growth arrest-specific 2
chrX_+_52255534	2.154	NM_001097597 NM_001097598 NM_001097604 NM_001097605 NM_001097592 NM_001097593 NM_001097594 NM_001097596 NM_020411 NM_133430	XAGE1C XAGE1E XAGE1A XAGE1B XAGE1D	X antigen family, member 1C X antigen family, member 1E X antigen family, member 1A X antigen family, member 1B X antigen family, member 1D
chr19_+_40465249	2.135	NM_021175	HAMP	hepcidin antimicrobial peptide
chr2_+_38746555	2.129	NM_138801	GALM	galactose mutarotase (aldose 1-epimerase)
chrX_-_52549818	2.067	NM_001097598 NM_001097597 NM_001097605 NM_001097604 NM_001097593 NM_001097592 NM_001097596 NM_001097594 NM_133430 NM_020411	XAGE1C XAGE1E XAGE1A XAGE1B XAGE1D	X antigen family, member 1C X antigen family, member 1E X antigen family, member 1A X antigen family, member 1B X antigen family, member 1D
chr15_-_56093477	2.054	NM_170697	ALDH1A2	aldehyde dehydrogenase 1 family, member A2
chr16_-_32106907	2.052		LOC100289574	hect domain and RLD 2 pseudogene
chr6_-_31882704	2.034	NM_021177	LSM2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr19_-_44518465	2.006		GMFG	glia maturation factor, gamma
chrX_+_52797004	2.002	NM_003147 NM_175698 NM_001164417	SSX2 SSX2B	synovial sarcoma, X breakpoint 2 synovial sarcoma, X breakpoint 2B
chr1_-_149004852	1.999		CTSS	cathepsin S
chrX_-_2892288	1.994	NM_000047	ARSE	arylsulfatase E (chondrodysplasia punctata 1)
chr17_-_36074812	1.947	NM_152349	KRT222	keratin 222
chr16_+_32660135	1.941		LOC100289574	hect domain and RLD 2 pseudogene
chr12_-_7935010	1.926		SLC2A14	solute carrier family 2 (facilitated glucose transporter), member 14
chr19_-_53436088	1.904	NM_001184900	CARD8	caspase recruitment domain family, member 8
chr1_+_39694849	1.894		MACF1	microtubule-actin crosslinking factor 1
chr17_-_78599695	1.882		B3GNTL1	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
chrX_-_48101044	1.876	NM_021014 NM_175711	SSX3	synovial sarcoma, X breakpoint 3
chr1_+_28705041	1.876	NM_001048199	RCC1	regulator of chromosome condensation 1
chr13_+_49100435	1.869	NM_138450	ARL11	ADP-ribosylation factor-like 11
chrX_-_137777382	1.858	NM_001139502	FGF13	fibroblast growth factor 13
chr7_+_73262283	1.834		LAT2	linker for activation of T cells family, member 2
chr12_-_52975777	1.832	NM_006163	NFE2	nuclear factor (erythroid-derived 2), 45kDa
chrX_-_52700674	1.821	NM_173358	SSX7	synovial sarcoma, X breakpoint 7
chr12_-_52975823	1.814		NFE2	nuclear factor (erythroid-derived 2), 45kDa
chr8_-_38127489	1.812	NM_000349	STAR	steroidogenic acute regulatory protein
chr2_-_96314148	1.811		SNRNP200	small nuclear ribonucleoprotein 200kDa (U5)
chr2_+_96365190	1.797	NM_015341	NCAPH	non-SMC condensin I complex, subunit H
chrX_+_7770302	1.785	NM_013452	VCX	variable charge, X-linked
chr9_+_130257254	1.782	NM_153436	ODF2	outer dense fiber of sperm tails 2
chr6_-_150099352	1.779		NUP43	nucleoporin 43kDa
chr6_-_31960735	1.771		EHMT2	euchromatic histone-lysine N-methyltransferase 2
chr19_+_50100843	1.765	NM_000041	APOE	apolipoprotein E
chr17_-_36938111	1.746	NM_002276	KRT19	keratin 19
chr16_+_20682812	1.718	NM_005622 NM_202000	ACSM3	acyl-CoA synthetase medium-chain family member 3
chr19_+_10673105	1.705	NM_031209	QTRT1	queuine tRNA-ribosyltransferase 1
chr11_-_33870411	1.699	NM_005574	LMO2	LIM domain only 2 (rhombotin-like 1)
chr3_-_184363157	1.665	NM_014398	LAMP3	lysosomal-associated membrane protein 3
chr12_-_120781002	1.661	NM_002150	HPD	4-hydroxyphenylpyruvate dioxygenase
chr5_+_139869819	1.655
chr7_+_73262264	1.640		LAT2	linker for activation of T cells family, member 2
chr2_-_27210792	1.635		PREB	prolactin regulatory element binding
chr16_+_11966464	1.621	NM_001192	TNFRSF17	tumor necrosis factor receptor superfamily, member 17
chrX_+_52528485	1.619	NM_001097597 NM_001097598 NM_001097604 NM_001097605 NM_001097592 NM_001097593 NM_001097594 NM_001097596 NM_020411 NM_133430	XAGE1C XAGE1E XAGE1A XAGE1B XAGE1D	X antigen family, member 1C X antigen family, member 1E X antigen family, member 1A X antigen family, member 1B X antigen family, member 1D
chrX_-_52562712	1.613	NM_001097598 NM_001097597 NM_001097605 NM_001097604 NM_001097593 NM_001097592 NM_001097596 NM_001097594 NM_133430 NM_020411	XAGE1C XAGE1E XAGE1A XAGE1B XAGE1D	X antigen family, member 1C X antigen family, member 1E X antigen family, member 1A X antigen family, member 1B X antigen family, member 1D
chr19_-_12858956	1.583	NM_006563	KLF1	Kruppel-like factor 1 (erythroid)
chrX_-_118610880	1.581	NM_001173488	NKRF	NFKB repressing factor
chr17_+_4621924	1.579	NM_003963	TM4SF5	transmembrane 4 L six family member 5
chr22_+_19248733	1.577		MED15	mediator complex subunit 15
chr8_-_94822387	1.574	NM_203390	RBM12B	RNA binding motif protein 12B
chr4_+_74496660	1.567		ALB	albumin
chr11_-_73371531	1.559	NM_003355	UCP2	uncoupling protein 2 (mitochondrial, proton carrier)
chr17_+_73721924	1.553		BIRC5	baculoviral IAP repeat containing 5
chr1_-_149611768	1.552	NM_003944	SELENBP1	selenium binding protein 1
chr19_+_60168463	1.549	NM_001174081	NLRP2	NLR family, pyrin domain containing 2
chr11_-_107235123	1.546	NM_017515	SLC35F2	solute carrier family 35, member F2
chr8_-_124497770	1.536		ATAD2	ATPase family, AAA domain containing 2
chr1_-_45868775	1.535		GPBP1L1	GC-rich promoter binding protein 1-like 1
chr7_-_99537362	1.533	NM_005916	MCM7	minichromosome maintenance complex component 7
chr1_+_15862887	1.525
chr6_-_32206029	1.524	NM_022110	FKBPL	FK506 binding protein like
chr19_+_811615	1.503		CFD	complement factor D (adipsin)
chr7_+_56099463	1.486		SUMF2	sulfatase modifying factor 2
chr8_+_43067817	1.482
chr19_-_12929033	1.480	NM_052850	GADD45GIP1	growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr6_+_31706345	1.477		PRRC2A	proline-rich coiled-coil 2A
chr10_-_7701619	1.476	NM_032817	ITIH5	inter-alpha (globulin) inhibitor H5
chr6_+_16237300	1.469		MYLIP	myosin regulatory light chain interacting protein
chr14_-_54720101	1.447		DLGAP5	discs, large (Drosophila) homolog-associated protein 5
chr2_-_27211023	1.440	NM_013388	PREB	prolactin regulatory element binding
chr3_-_180452338	1.434	NM_171830	KCNMB3	potassium large conductance calcium-activated channel, subfamily M beta member 3
chr2_-_70382633	1.434	NM_032822	FAM136A	family with sequence similarity 136, member A
chr17_+_73721871	1.424	NM_001012270 NM_001012271 NM_001168	BIRC5	baculoviral IAP repeat containing 5
chr6_+_16237264	1.421	NM_013262	MYLIP	myosin regulatory light chain interacting protein
chr11_+_118460779	1.419	NM_000190	HMBS	hydroxymethylbilane synthase
chr8_-_145613034	1.414		SLC39A4	solute carrier family 39 (zinc transporter), member 4
chr11_-_73371452	1.408		UCP2	uncoupling protein 2 (mitochondrial, proton carrier)
chr12_-_122400937	1.404	NM_001167856 NM_018183	SBNO1	strawberry notch homolog 1 (Drosophila)
chr2_-_74546042	1.401	NM_001146158 NM_006302	MOGS	mannosyl-oligosaccharide glucosidase
chrX_-_52276878	1.395	NM_001097598 NM_001097597 NM_001097605 NM_001097604 NM_001097593 NM_001097592 NM_001097596 NM_001097594 NM_133430 NM_020411	XAGE1C XAGE1E XAGE1A XAGE1B XAGE1D	X antigen family, member 1C X antigen family, member 1E X antigen family, member 1A X antigen family, member 1B X antigen family, member 1D
chr15_-_73036827	1.389	NM_017793	RPP25	ribonuclease P/MRP 25kDa subunit
chr6_-_2848460	1.380	NM_004155	SERPINB9	serpin peptidase inhibitor, clade B (ovalbumin), member 9
chr22_-_40666168	1.362	NM_001110215	CENPM	centromere protein M
chr19_-_52427698	1.362	NM_001127240 NM_001127241 NM_001127242	BBC3	BCL2 binding component 3
chr7_-_99518294	1.356		ZNF3	zinc finger protein 3
chr7_-_99518106	1.348
chr2_-_98646367	1.347	NM_001160154	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr16_-_68349445	1.343
chr1_-_149004916	1.342	NM_004079	CTSS	cathepsin S
chr6_-_150001376	1.341	NM_007044	KATNA1	katanin p60 (ATPase containing) subunit A 1
chr2_-_74546009	1.333		MOGS	mannosyl-oligosaccharide glucosidase
chr6_-_44341222	1.320		NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr12_+_120132233	1.314		P2RX4	purinergic receptor P2X, ligand-gated ion channel, 4
chr3_-_180452096	1.306	NM_014407	KCNMB3	potassium large conductance calcium-activated channel, subfamily M beta member 3
chr16_-_28528780	1.296	NM_001055 NM_177529	SULT1A1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr2_-_27211019	1.294		PREB	prolactin regulatory element binding
chr16_-_73576508	1.291	NM_030581	WDR59	WD repeat domain 59
chr2_-_27210990	1.282		PREB	prolactin regulatory element binding
chr7_-_1562272	1.272	NM_001097620	TMEM184A	transmembrane protein 184A
chr4_-_103464491	1.266	NM_001135148	SLC39A8	solute carrier family 39 (zinc transporter), member 8
chr1_-_149004879	1.264		CTSS	cathepsin S
chr9_-_19117462	1.263		PLIN2	perilipin 2
chr16_+_29597965	1.263		QPRT	quinolinate phosphoribosyltransferase
chr19_+_14460757	1.259	NM_001146693	LOC100130932	small nuclear ribonucleoprotein G-like protein
chr12_-_55432348	1.258	NM_000946	PRIM1	primase, DNA, polypeptide 1 (49kDa)
chr2_+_96672200	1.249	NM_001113382	FER1L5	fer-1-like 5 (C. elegans)
chr3_+_42607345	1.247		SS18L2	synovial sarcoma translocation gene on chromosome 18-like 2
chr2_-_128332161	1.239		POLR2D	polymerase (RNA) II (DNA directed) polypeptide D
chr4_-_23500706	1.237	NM_013261	PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr1_-_32157845	1.208	NM_001195100 NM_001195101	PTP4A2	protein tyrosine phosphatase type IVA, member 2
chr16_+_65558878	1.201	NM_001185176	CES3	carboxylesterase 3
chr10_-_43383912	1.199	NM_005674	ZNF239	zinc finger protein 239
chr9_-_19117494	1.193	NM_001122	PLIN2	perilipin 2
chr6_-_31727460	1.191
chr15_+_43102593	1.188	NM_003104	SORD	sorbitol dehydrogenase
chr9_-_115178161	1.187	NM_031219	HDHD3	haloacid dehalogenase-like hydrolase domain containing 3
chr19_+_55123770	1.185	NM_012068	ATF5	activating transcription factor 5
chr3_+_4510160	1.184		ITPR1	inositol 1,4,5-triphosphate receptor, type 1
chr12_+_6893751	1.182	NM_001975	ENO2	enolase 2 (gamma, neuronal)
chr4_-_40212670	1.177	NM_019027	RBM47	RNA binding motif protein 47
chr2_+_38746742	1.174		GALM	galactose mutarotase (aldose 1-epimerase)
chr7_+_98908364	1.173		ZNF789	zinc finger protein 789
chr12_-_122272346	1.164	NM_022782	MPHOSPH9	M-phase phosphoprotein 9
chr15_-_63199228	1.157		PDCD7	programmed cell death 7
chr6_-_31871452	1.156		VARS	valyl-tRNA synthetase
chr3_-_143201878	1.151	NM_001178140	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)
chr14_-_22496196	1.149		HAUS4	HAUS augmin-like complex, subunit 4
chr6_+_34832848	1.149	NM_003093	SNRPC	small nuclear ribonucleoprotein polypeptide C
chr7_+_63763916	1.142	NM_001013746 NM_016220	ZNF107	zinc finger protein 107
chr3_+_42607301	1.128	NM_016305	SS18L2	synovial sarcoma translocation gene on chromosome 18-like 2
chr15_-_20585847	1.127	NM_001008860 NM_001008892 NM_001008894 NM_001184888 NM_001184889 NM_030922	NIPA2	non imprinted in Prader-Willi/Angelman syndrome 2
chr14_-_22496098	1.126	NM_001166269 NM_001166270 NM_017815	HAUS4	HAUS augmin-like complex, subunit 4
chr3_+_128799902	1.124	NM_004526	MCM2	minichromosome maintenance complex component 2
chr16_-_2276875	1.119
chrX_-_48156287	1.117	NM_001034832 NM_001040612 NM_005636 NM_175729	SSX4B SSX4	synovial sarcoma, X breakpoint 4B synovial sarcoma, X breakpoint 4
chr19_+_1022208	1.114		HMHA1	histocompatibility (minor) HA-1
chr11_-_62364203	1.103	NM_018093	WDR74	WD repeat domain 74
chr2_+_151974630	1.103	NM_001177663 NM_018151 NM_001177664	RIF1	RAP1 interacting factor homolog (yeast)
chr3_+_128799964	1.100		MCM2	minichromosome maintenance complex component 2
chr2_+_219283751	1.097	NM_014640	TTLL4	tubulin tyrosine ligase-like family, member 4
chr16_+_87397686	1.097	NM_030928	CDT1	chromatin licensing and DNA replication factor 1
chr22_+_19458378	1.096	NM_000185	SERPIND1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr10_-_69901648	1.095		DNA2	DNA replication helicase 2 homolog (yeast)
chr8_-_145613058	1.090	NM_130849	SLC39A4	solute carrier family 39 (zinc transporter), member 4
chrX_+_48127911	1.088	NM_001034832 NM_001040612 NM_005636 NM_175729	SSX4B SSX4	synovial sarcoma, X breakpoint 4B synovial sarcoma, X breakpoint 4
chr5_-_149772469	1.084	NM_001025159 NM_004355 NM_001025158	CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr5_+_37415139	1.083		WDR70	WD repeat domain 70
chr17_+_8093319	1.075	NM_012393	PFAS	phosphoribosylformylglycinamidine synthase
chr19_-_11500912	1.070	NM_001142464 NM_001142465 NM_016581	ECSIT	ECSIT homolog (Drosophila)
chr2_+_85696818	1.067		USP39	ubiquitin specific peptidase 39
chrX_+_48427103	1.067	NM_000377	WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr4_-_46605980	1.056	NM_130902	COX7B2	cytochrome c oxidase subunit VIIb2
chr22_+_20252015	1.054		UBE2L3	ubiquitin-conjugating enzyme E2L 3
chr19_+_17198012	1.049	NM_024578	OCEL1	occludin/ELL domain containing 1
chr3_-_9895633	1.049	NM_022094	CIDEC	cell death-inducing DFFA-like effector c
chr16_+_43009	1.041		SNRNP25	small nuclear ribonucleoprotein 25kDa (U11/U12)
chr7_-_144164051	1.039	NM_001042482 NM_022445	TPK1	thiamin pyrophosphokinase 1
chr7_+_73506333	1.032	NM_005685	GTF2IRD1	GTF2I repeat domain containing 1
chr7_+_98908449	1.030	NM_001013258 NM_213603	ZNF789	zinc finger protein 789
chr16_-_28515868	1.028	NM_001054	SULT1A2	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr12_+_53178834	1.027	NM_001184976	NCKAP1L	NCK-associated protein 1-like
chr6_+_34313347	1.025		HMGA1	high mobility group AT-hook 1
chr2_+_86280066	1.021	NM_016622 NM_145644	MRPL35	mitochondrial ribosomal protein L35
chr12_+_53177806	1.017		NCKAP1L	NCK-associated protein 1-like
chr2_+_85696791	1.017	NM_006590	USP39	ubiquitin specific peptidase 39
chr1_-_40121692	1.013		TRIT1	tRNA isopentenyltransferase 1
chr1_+_244954153	1.011		SCCPDH	saccharopine dehydrogenase (putative)
chr16_+_70654625	1.010	NM_020995	HPR	haptoglobin-related protein

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.74	6.08e-04	GO:0006396	RNA processing
1.72	7.54e-03	GO:0016071	mRNA metabolic process
1.85	1.15e-02	GO:0006397	mRNA processing
1.30	3.25e-02	GO:0090304	nucleic acid metabolic process
1.90	3.92e-02	GO:0008380	RNA splicing

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.17	1.98e-03	GO:0005634	nucleus
5.17	2.08e-03	GO:0005689	U12-type spliceosomal complex
1.31	3.10e-03	GO:0044428	nuclear part
1.27	1.26e-02	GO:0031974	membrane-enclosed lumen
2.32	1.42e-02	GO:0005681	spliceosomal complex
1.27	1.43e-02	GO:0043233	organelle lumen
1.07	2.05e-02	GO:0005622	intracellular
1.62	2.25e-02	GO:0030529	ribonucleoprotein complex
1.07	3.56e-02	GO:0044424	intracellular part
1.25	4.51e-02	GO:0070013	intracellular organelle lumen

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.31	3.59e-05	GO:0003676	nucleic acid binding
1.54	5.21e-03	GO:0003723	RNA binding