Motif ID: GATA1..3.p2

Z-value: 2.275


Transcription factors associated with GATA1..3.p2:

Gene SymbolEntrez IDGene Name
GATA1 2623 GATA binding protein 1 (globin transcription factor 1)
GATA2 2624 GATA binding protein 2
GATA3 2625 GATA binding protein 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GATA2chr3_-_129694717-0.562.4e-02Click!
GATA1chrX_+_48529905-0.439.4e-02Click!
GATA3chr10_+_8136639-0.048.8e-01Click!


Activity profile for motif GATA1..3.p2.

activity profile for motif GATA1..3.p2


Sorted Z-values histogram for motif GATA1..3.p2

Sorted Z-values for motif GATA1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_189752575 5.803 NM_000393
COL5A2
collagen, type V, alpha 2
chr12_+_1608672 4.949 NM_032642
WNT5B
wingless-type MMTV integration site family, member 5B
chr5_+_140870881 4.821


chr5_+_140871107 4.655


chr17_+_39990124 4.624 NM_001466
FZD2
frizzled homolog 2 (Drosophila)
chr11_-_35503720 4.501 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr2_+_189547323 4.280 NM_000090
COL3A1
collagen, type III, alpha 1
chr2_+_189547358 4.202 COL3A1
collagen, type III, alpha 1
chr2_+_189547377 3.926 COL3A1
collagen, type III, alpha 1
chr17_-_45617899 3.816 COL1A1
collagen, type I, alpha 1
chr3_-_129023850 3.503 NM_007283
MGLL
monoglyceride lipase
chr10_+_75343352 3.278 PLAU
plasminogen activator, urokinase
chr1_+_114323552 3.155 NM_020190
OLFML3
olfactomedin-like 3
chr3_+_161040343 2.790 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr17_-_45633873 2.753 COL1A1
collagen, type I, alpha 1
chr9_-_16717887 2.741 BNC2
basonuclin 2
chr17_-_45619038 2.696 COL1A1
collagen, type I, alpha 1
chr12_-_48902692 2.571 NM_001113547
LIMA1
LIM domain and actin binding 1
chr4_+_89147821 2.484 NM_000297
PKD2
polycystic kidney disease 2 (autosomal dominant)
chr12_+_79634820 2.356 NM_005593
MYF5
myogenic factor 5
chr1_-_27871287 2.300 IFI6
interferon, alpha-inducible protein 6
chr14_+_64077171 2.260 HSPA2
heat shock 70kDa protein 2
chr2_-_175578156 2.209 NM_001025201
NM_001822
CHN1

chimerin (chimaerin) 1

chr11_-_111287657 2.140 NM_001885
CRYAB
crystallin, alpha B
chr11_+_130745580 2.059 NM_001048209
NTM
neurotrimin
chr1_-_27871245 2.058 IFI6
interferon, alpha-inducible protein 6
chr11_-_27698800 2.013 NM_001143805
NM_001143806
NM_170732
BDNF


brain-derived neurotrophic factor


chr12_+_79625538 1.999 NM_002469
MYF6
myogenic factor 6 (herculin)
chr1_+_162795328 1.973 NM_002585
PBX1
pre-B-cell leukemia homeobox 1
chr2_-_210876560 1.935 NM_079422
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr3_+_161040439 1.898 SCHIP1
schwannomin interacting protein 1
chr2_-_215949566 1.863 FN1
fibronectin 1
chr8_+_70541412 1.811 NM_001128204
NM_015170
SULF1

sulfatase 1

chr8_+_70567581 1.800 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr1_-_103346482 1.794 COL11A1
collagen, type XI, alpha 1
chrX_-_10495476 1.791 NM_001193278
NM_001193279
NM_001193280
NM_001193281
MID1



midline 1 (Opitz/BBB syndrome)



chrX_+_135058402 1.768 NM_001159700
FHL1
four and a half LIM domains 1
chr8_+_22493928 1.766 NM_176871
NM_198042
PDLIM2

PDZ and LIM domain 2 (mystique)

chr8_-_18915443 1.754 NM_015310
PSD3
pleckstrin and Sec7 domain containing 3
chr20_+_19863716 1.749 RIN2
Ras and Rab interactor 2
chr2_+_202607554 1.735 NM_003507
FZD7
frizzled homolog 7 (Drosophila)
chr3_-_55496607 1.725 WNT5A
wingless-type MMTV integration site family, member 5A
chr7_-_5534737 1.680 ACTB
actin, beta
chr1_-_85816520 1.671 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr15_-_32875040 1.655 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr8_+_70567634 1.645 SULF1
sulfatase 1
chr5_+_82803248 1.644 NM_001126336
NM_001164097
NM_001164098
NM_004385
VCAN



versican



chr2_+_170074457 1.607 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr13_+_100902942 1.601 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr10_+_17311242 1.594 VIM
vimentin
chr19_+_16296632 1.580 NM_016270
KLF2
Kruppel-like factor 2 (lung)
chr9_+_123126652 1.580 GSN
gelsolin
chr3_-_51968995 1.563 PCBP4
poly(rC) binding protein 4
chr10_+_17311347 1.558 VIM
vimentin
chr3_-_115826481 1.551 NM_001164346
ZBTB20
zinc finger and BTB domain containing 20
chr7_-_151142858 1.546 NM_001040633
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr10_+_17311307 1.544 VIM
vimentin
chr10_+_11247059 1.537 CELF2
CUGBP, Elav-like family member 2
chr1_-_103346639 1.536 NM_001190709
NM_001854
NM_080629
NM_080630
COL11A1



collagen, type XI, alpha 1



chrX_+_48253007 1.534 NM_203474
NM_203475
PORCN

porcupine homolog (Drosophila)

chr9_+_111582317 1.525 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr11_-_85146691 1.507 NM_001162951
NM_001162953
SYTL2

synaptotagmin-like 2

chr13_-_105985313 1.490 NM_004093
EFNB2
ephrin-B2
chr1_-_56750235 1.477 PPAP2B
phosphatidic acid phosphatase type 2B
chr10_-_79067552 1.477 NM_001014797
NM_001161352
NM_001161353
NM_002247
KCNMA1



potassium large conductance calcium-activated channel, subfamily M, alpha member 1



chr15_+_41597097 1.450 NM_002373
MAP1A
microtubule-associated protein 1A
chr8_-_18585721 1.447 PSD3
pleckstrin and Sec7 domain containing 3
chr2_-_217248967 1.440 IGFBP5
insulin-like growth factor binding protein 5
chr10_+_17311282 1.431 VIM
vimentin
chr10_+_17311283 1.428 VIM
vimentin
chr11_-_47427263 1.422 NM_005055
NM_032645
RAPSN

receptor-associated protein of the synapse

chr19_-_54835162 1.421 NM_006270
RRAS
related RAS viral (r-ras) oncogene homolog
chr9_+_33614214 1.406 ANXA2P2
annexin A2 pseudogene 2
chr1_+_63861474 1.399 NM_001172818
PGM1
phosphoglucomutase 1
chr7_+_115952279 1.391 NM_001172895
CAV1
caveolin 1, caveolae protein, 22kDa
chr5_+_125828685 1.382 NM_001146322
GRAMD3
GRAM domain containing 3
chr7_+_115952325 1.381 CAV1
caveolin 1, caveolae protein, 22kDa
chr7_-_5534252 1.376 ACTB
actin, beta
chr14_+_95792299 1.362 NM_000710
BDKRB1
bradykinin receptor B1
chr21_+_46370220 1.360 COL6A2
collagen, type VI, alpha 2
chr5_+_131621287 1.356 PDLIM4
PDZ and LIM domain 4
chr7_+_115952074 1.330 NM_001753
CAV1
caveolin 1, caveolae protein, 22kDa
chr10_+_63331018 1.298 NM_032199
ARID5B
AT rich interactive domain 5B (MRF1-like)
chrX_+_114701432 1.290 NM_005032
PLS3
plastin 3
chr1_+_234372454 1.281 NM_003272
GPR137B
G protein-coupled receptor 137B
chr5_+_17270781 1.277 BASP1
brain abundant, membrane attached signal protein 1
chr16_+_31390567 1.259 NM_001042454
NM_001164719
TGFB1I1

transforming growth factor beta 1 induced transcript 1

chr1_-_27871306 1.254 NM_002038
NM_022872
NM_022873
IFI6


interferon, alpha-inducible protein 6


chr13_-_32678142 1.249 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr5_+_86600483 1.247 NM_022650
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr2_-_38156811 1.238 NM_000104
CYP1B1
cytochrome P450, family 1, subfamily B, polypeptide 1
chr11_+_131285747 1.235 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr1_-_153209625 1.213 NM_001130040
NM_183001
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chr2_-_38156769 1.212 CYP1B1
cytochrome P450, family 1, subfamily B, polypeptide 1
chr8_-_108579270 1.208 NM_001146
ANGPT1
angiopoietin 1
chr5_-_141973875 1.205 NM_033137
FGF1
fibroblast growth factor 1 (acidic)
chr7_+_115953582 1.192 NM_001172896
NM_001172897
CAV1

caveolin 1, caveolae protein, 22kDa

chr12_+_52708460 1.187 NM_004503
HOXC6
homeobox C6
chr10_-_127501683 1.149 UROS
uroporphyrinogen III synthase
chr2_-_1727324 1.143 PXDN
peroxidasin homolog (Drosophila)
chr10_-_104463947 1.140 NM_004311
ARL3
ADP-ribosylation factor-like 3
chr6_-_80713589 1.139 NM_022726
ELOVL4
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
chr3_-_115825742 1.131 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr17_-_44037332 1.120 NM_018952
HOXB6
homeobox B6
chr4_-_57671307 1.115 IGFBP7
insulin-like growth factor binding protein 7
chrX_-_13745108 1.112 GPM6B
glycoprotein M6B
chr3_-_55496370 1.110 NM_003392
WNT5A
wingless-type MMTV integration site family, member 5A
chr7_-_81237162 1.105 NM_000601
NM_001010931
NM_001010932
NM_001010933
NM_001010934
HGF




hepatocyte growth factor (hepapoietin A; scatter factor)




chr1_-_153477511 1.104 GBA
glucosidase, beta, acid
chrX_-_10605726 1.099 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr11_+_113672407 1.098 NNMT
nicotinamide N-methyltransferase
chr18_-_51219880 1.097 TCF4
transcription factor 4
chr10_+_70745615 1.091 NM_033496
HK1
hexokinase 1
chr4_-_57671273 1.084 NM_001553
IGFBP7
insulin-like growth factor binding protein 7
chr11_+_113672378 1.078 NNMT
nicotinamide N-methyltransferase
chr2_-_1727292 1.076 NM_012293
PXDN
peroxidasin homolog (Drosophila)
chr2_-_1727247 1.066 PXDN
peroxidasin homolog (Drosophila)
chr5_+_119827797 1.066 PRR16
proline rich 16
chr2_-_215967442 1.065 FN1
fibronectin 1
chr20_-_47532585 1.064 NM_004975
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr4_-_57671112 1.064 IGFBP7
insulin-like growth factor binding protein 7
chr10_+_104493714 1.053 NM_001083913
C10orf26
chromosome 10 open reading frame 26
chr10_+_70517823 1.051 NM_002727
SRGN
serglycin
chr13_-_37070862 1.046 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr10_-_127501822 1.043 NM_000375
UROS
uroporphyrinogen III synthase
chrX_-_111953009 1.041 NM_001113490
AMOT
angiomotin
chrX_-_21686079 1.036 NM_014332
SMPX
small muscle protein, X-linked
chr9_+_35819208 1.025 NM_016446
NM_001042589
TMEM8B

transmembrane protein 8B

chr11_+_116575249 1.022 NM_001001522
NM_003186
TAGLN

transgelin

chr11_-_11986704 1.020 NM_001018057
DKK3
dickkopf homolog 3 (Xenopus laevis)
chr10_+_70517863 1.017 SRGN
serglycin
chr3_-_124822113 1.004 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr4_+_169654742 0.997 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chr13_-_32757835 0.995 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr19_+_16296734 0.994 KLF2
Kruppel-like factor 2 (lung)
chr12_+_77782719 0.994 SYT1
synaptotagmin I
chr12_-_90097384 0.988 NM_133503
DCN
decorin
chrX_-_13744933 0.983 GPM6B
glycoprotein M6B
chr10_-_79067210 0.962 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr3_-_109423858 0.961 NM_018010
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr4_+_169989680 0.960 NM_001166110
PALLD
palladin, cytoskeletal associated protein
chr4_+_54790020 0.955 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr2_-_237987509 0.951 COL6A3
collagen, type VI, alpha 3
chr3_-_55490401 0.950 WNT5A
wingless-type MMTV integration site family, member 5A
chr10_+_102782156 0.947 SFXN3
sideroflexin 3
chr1_-_68071635 0.944 NM_018841
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr1_+_154095883 0.942 NM_152280
SYT11
synaptotagmin XI
chrX_-_37916138 0.938 SRPX
sushi-repeat containing protein, X-linked
chr2_-_175337386 0.936 NM_000079
NM_001039523
CHRNA1

cholinergic receptor, nicotinic, alpha 1 (muscle)

chr12_-_90096275 0.935 NM_133504
NM_133505
NM_133506
NM_133507
DCN



decorin



chr16_+_83411086 0.932 NM_031476
CRISPLD2
cysteine-rich secretory protein LCCL domain containing 2
chr10_+_3141596 0.928 PFKP
phosphofructokinase, platelet
chr20_+_9236446 0.927 NM_000933
PLCB4
phospholipase C, beta 4
chr9_+_35819375 0.926 NM_001042590
TMEM8B
transmembrane protein 8B
chr2_-_56004366 0.922 NM_001039348
NM_001039349
EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

chr4_+_72423633 0.917 NM_003759
SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr6_+_33151703 0.912 NM_002121
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr1_-_153477673 0.911 NM_001171812
NM_000157
GBA

glucosidase, beta, acid

chr21_+_29439768 0.907 C21orf7
chromosome 21 open reading frame 7
chr3_-_124821868 0.905 MYLK
myosin light chain kinase
chr6_+_30018287 0.904 NM_002116
HLA-A
major histocompatibility complex, class I, A
chr2_-_237987579 0.898 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
COL6A3




collagen, type VI, alpha 3




chr12_+_13240868 0.894 NM_001423
EMP1
epithelial membrane protein 1
chr15_+_68971835 0.893 NM_001199017
NM_017691
NM_001199018
LRRC49


leucine rich repeat containing 49


chr7_+_90176647 0.888 NM_012395
CDK14
cyclin-dependent kinase 14
chr6_-_112147946 0.884 NM_153047
FYN
FYN oncogene related to SRC, FGR, YES
chr11_+_112337199 0.882 NM_000615
NM_001076682
NM_181351
NCAM1


neural cell adhesion molecule 1


chr5_+_119827903 0.880 NM_016644
PRR16
proline rich 16
chr11_-_8849485 0.876 ST5
suppression of tumorigenicity 5
chr5_+_125723686 0.873 NM_001146319
GRAMD3
GRAM domain containing 3
chr1_-_42738535 0.870 TMSB4XP1
thymosin beta 4, X-linked pseudogene 1
chr9_+_113698844 0.863 NM_003358
UGCG
UDP-glucose ceramide glucosyltransferase
chr10_-_92671005 0.862 NM_014391
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chrX_+_51503219 0.850 NM_018094
GSPT2
G1 to S phase transition 2
chr12_+_46799279 0.848 NM_000289
PFKM
phosphofructokinase, muscle
chr8_-_119192985 0.843 NM_000127
EXT1
exostosin 1
chr10_+_102782151 0.840 SFXN3
sideroflexin 3
chr15_-_81667169 0.838 NM_016073
HDGFRP3
hepatoma-derived growth factor, related protein 3
chr10_-_105202139 0.838 NM_015916
CALHM2
calcium homeostasis modulator 2
chr5_+_140733664 0.837 NM_018919
NM_032086
PCDHGA6

protocadherin gamma subfamily A, 6

chr8_+_37773915 0.834 GPR124
G protein-coupled receptor 124
chr3_-_115960807 0.829 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr11_-_14337167 0.819 NM_012250
RRAS2
related RAS viral (r-ras) oncogene homolog 2
chr11_-_64403712 0.818 EHD1
EH-domain containing 1
chr8_-_93099040 0.809 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr7_+_98084531 0.799 NM_002523
NPTX2
neuronal pentraxin II
chr5_+_131621230 0.799 NM_001131027
NM_003687
PDLIM4

PDZ and LIM domain 4

chr10_-_79067400 0.798 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr5_-_172688024 0.795 STC2
stanniocalcin 2
chr5_+_36644187 0.794 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr4_+_84175262 0.781 NM_016129
COPS4
COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)
chr2_-_237987554 0.775 COL6A3
collagen, type VI, alpha 3
chrX_-_106130098 0.773 NM_001085354
NM_024657
MORC4

MORC family CW-type zinc finger 4

chr5_+_53787187 0.772 NM_006308
HSPB3
heat shock 27kDa protein 3
chrX_+_135106578 0.770 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr7_-_139948780 0.770 NM_015689
DENND2A
DENN/MADD domain containing 2A
chr5_+_131621276 0.770 PDLIM4
PDZ and LIM domain 4
chr5_-_81082699 0.769 NM_012446
SSBP2
single-stranded DNA binding protein 2
chr3_-_45242072 0.769 TMEM158
transmembrane protein 158 (gene/pseudogene)
chr13_+_109932934 0.763 COL4A2
collagen, type IV, alpha 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.18 6.87e-08 GO:0032501 multicellular organismal process
1.25 3.27e-07 GO:0048731 system development
1.22 3.13e-06 GO:0048856 anatomical structure development
1.20 1.05e-05 GO:0007275 multicellular organismal development
1.18 3.98e-05 GO:0032502 developmental process
1.13 2.04e-04 GO:0050896 response to stimulus
1.16 1.55e-03 GO:0023052 signaling
1.37 3.49e-03 GO:0009888 tissue development
1.60 9.30e-03 GO:0022603 regulation of anatomical structure morphogenesis
1.16 1.01e-02 GO:0007165 signal transduction
1.26 1.25e-02 GO:0007399 nervous system development
1.21 1.45e-02 GO:0048869 cellular developmental process
1.22 1.50e-02 GO:0030154 cell differentiation
1.72 1.55e-02 GO:0003012 muscle system process
1.34 1.59e-02 GO:0048699 generation of neurons
1.27 2.33e-02 GO:0051239 regulation of multicellular organismal process
1.32 2.60e-02 GO:0022008 neurogenesis
1.21 3.31e-02 GO:0048583 regulation of response to stimulus
1.21 3.69e-02 GO:0048513 organ development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.25 3.31e-03 GO:0005856 cytoskeleton
1.16 7.51e-03 GO:0043234 protein complex
1.07 1.54e-02 GO:0005737 cytoplasm
1.93 1.73e-02 GO:0030017 sarcomere
1.45 1.89e-02 GO:0043005 neuron projection
1.80 2.36e-02 GO:0043292 contractile fiber
1.13 3.24e-02 GO:0005886 plasma membrane
1.13 3.73e-02 GO:0071944 cell periphery
1.13 4.04e-02 GO:0032991 macromolecular complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.09 2.76e-03 GO:0005515 protein binding
1.28 2.08e-02 GO:0005102 receptor binding