Motif ID: EGR1..3.p2

Z-value: 0.738


Transcription factors associated with EGR1..3.p2:

Gene SymbolEntrez IDGene Name
EGR1 1958 early growth response 1
EGR2 1959 early growth response 2 (Krox-20 homolog, Drosophila)
EGR3 1960 early growth response 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EGR2chr10_-_642460800.601.3e-02Click!
EGR1chr5_+_137829065-0.078.0e-01Click!
EGR3chr8_-_226066530.019.6e-01Click!


Activity profile for motif EGR1..3.p2.

activity profile for motif EGR1..3.p2


Sorted Z-values histogram for motif EGR1..3.p2

Sorted Z-values for motif EGR1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EGR1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_32574185 1.054 NM_023009
MARCKSL1
MARCKS-like 1
chr19_+_16296632 0.668 NM_016270
KLF2
Kruppel-like factor 2 (lung)
chr19_+_16296734 0.648 KLF2
Kruppel-like factor 2 (lung)
chr2_+_233927892 0.580 DGKD
diacylglycerol kinase, delta 130kDa
chr17_-_76622967 0.555 FLJ90757
hypothetical LOC440465
chr9_+_127549437 0.526 NM_006195
PBX3
pre-B-cell leukemia homeobox 3
chr3_-_172660545 0.509 NM_001161560
NM_001161561
NM_001161562
NM_001161563
NM_001161564
NM_001161565
NM_001161566
NM_015028
TNIK







TRAF2 and NCK interacting kinase







chr10_+_11099860 0.492 NM_006561
CELF2
CUGBP, Elav-like family member 2
chr5_-_88215034 0.468 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr19_+_4920126 0.463 KDM4B
lysine (K)-specific demethylase 4B
chr10_+_11100075 0.456 CELF2
CUGBP, Elav-like family member 2
chr1_+_148388870 0.448 PLEKHO1
pleckstrin homology domain containing, family O member 1
chr1_-_25128951 0.446 RUNX3
runt-related transcription factor 3
chr10_-_74925724 0.440 PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr16_+_84204424 0.423 NM_014615
KIAA0182
KIAA0182
chr1_+_148389039 0.411 PLEKHO1
pleckstrin homology domain containing, family O member 1
chr15_-_58671929 0.401 NM_134262
RORA
RAR-related orphan receptor A
chr19_-_2653738 0.398 NM_052847
GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr12_+_69046241 0.392 NM_014505
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr16_+_29725597 0.382


chrY_-_1531733 0.369 NM_001173474
NM_004192
ASMTL

acetylserotonin O-methyltransferase-like

chrX_-_1531733 0.369 NM_001173474
NM_004192
ASMTL

acetylserotonin O-methyltransferase-like

chr9_-_15500899 0.366 NM_001128217
NM_033222
PSIP1

PC4 and SFRS1 interacting protein 1

chrX_+_9392980 0.363 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr10_+_89613399 0.362 PTEN
phosphatase and tensin homolog
chr2_+_233927880 0.361 NM_152879
DGKD
diacylglycerol kinase, delta 130kDa
chr16_+_29725665 0.354


chr8_-_57286381 0.353 PLAG1
pleiomorphic adenoma gene 1
chr15_-_59308708 0.346 RORA
RAR-related orphan receptor A
chr10_-_64248932 0.344 NM_001136178
EGR2
early growth response 2
chr10_+_89613071 0.335 NM_000314
PTEN
phosphatase and tensin homolog
chr17_-_63798851 0.334 NM_001174166
NM_004694
SLC16A6

solute carrier family 16, member 6 (monocarboxylic acid transporter 7)

chr20_+_34357604 0.333 DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr11_+_46359878 0.331 NM_001012333
MDK
midkine (neurite growth-promoting factor 2)
chr15_-_59308770 0.330 NM_134261
RORA
RAR-related orphan receptor A
chr17_+_63252668 0.327 BPTF
bromodomain PHD finger transcription factor
chr19_+_1022208 0.325 HMHA1
histocompatibility (minor) HA-1
chr19_-_18578467 0.325 CRLF1
cytokine receptor-like factor 1
chr6_+_37245860 0.318 NM_002648
PIM1
pim-1 oncogene
chr9_+_136358145 0.317 RXRA
retinoid X receptor, alpha
chrX_-_132947290 0.313 NM_001164617
NM_001164618
NM_001164619
NM_004484
GPC3



glypican 3



chr4_+_154606900 0.312 NM_001131007
NM_015196
KIAA0922

KIAA0922

chr4_-_105631915 0.312 NM_025212
CXXC4
CXXC finger protein 4
chr6_-_46566969 0.308 RCAN2
regulator of calcineurin 2
chr7_+_64975596 0.308 NM_173517
VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chr22_-_37878394 0.307 NM_175709
CBX7
chromobox homolog 7
chr1_-_15723363 0.302 NM_001229
NM_032996
CASP9

caspase 9, apoptosis-related cysteine peptidase

chr20_+_61039803 0.302 NM_017896
C20orf11
chromosome 20 open reading frame 11
chr9_+_35819208 0.299 NM_016446
NM_001042589
TMEM8B

transmembrane protein 8B

chr13_+_19430788 0.298 NM_003453
NM_197968
NM_001190964
ZMYM2


zinc finger, MYM-type 2


chr10_+_11100111 0.296 CELF2
CUGBP, Elav-like family member 2
chr6_+_132170888 0.296 ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr11_+_46359821 0.296 MDK
midkine (neurite growth-promoting factor 2)
chr7_+_102502852 0.294 ARMC10
armadillo repeat containing 10
chr20_-_61039672 0.293 DIDO1
death inducer-obliterator 1
chr16_+_68157611 0.292 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chrX_-_132947141 0.290 GPC3
glypican 3
chr11_+_46359781 0.290 NM_002391
MDK
midkine (neurite growth-promoting factor 2)
chr9_+_35819375 0.289 NM_001042590
TMEM8B
transmembrane protein 8B
chr19_-_2653662 0.289 GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr17_-_3546047 0.288 P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr6_+_138230045 0.281 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr11_+_46359855 0.276 MDK
midkine (neurite growth-promoting factor 2)
chr19_+_2427122 0.275 NM_015675
GADD45B
growth arrest and DNA-damage-inducible, beta
chr6_-_109883864 0.275 NM_001159291
NM_022765
MICAL1

microtubule associated monoxygenase, calponin and LIM domain containing 1

chr6_-_109883635 0.274 MICAL1
microtubule associated monoxygenase, calponin and LIM domain containing 1
chr16_+_65018316 0.270 NM_001136106
NM_001178020
NM_001197224
NM_001197225
BEAN1



brain expressed, associated with NEDD4, 1



chr13_+_19430906 0.269 NM_001190965
ZMYM2
zinc finger, MYM-type 2
chr11_+_46359836 0.269 MDK
midkine (neurite growth-promoting factor 2)
chr5_-_172688024 0.268 STC2
stanniocalcin 2
chr6_+_135544170 0.268 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr6_-_111243023 0.264 CDK19
cyclin-dependent kinase 19
chr22_+_42751487 0.264 NM_013327
PARVB
parvin, beta
chr5_-_81082699 0.263 NM_012446
SSBP2
single-stranded DNA binding protein 2
chr6_+_89848229 0.263 PNRC1
proline-rich nuclear receptor coactivator 1
chr9_+_89302239 0.261 DAPK1
death-associated protein kinase 1
chr19_-_18578631 0.261 NM_004750
CRLF1
cytokine receptor-like factor 1
chr2_+_96845704 0.261 NM_017623
NM_199078
CNNM3

cyclin M3

chr6_-_109883778 0.261 MICAL1
microtubule associated monoxygenase, calponin and LIM domain containing 1
chr18_-_51406359 0.261 TCF4
transcription factor 4
chr17_-_3546236 0.260 NM_002561
NM_175080
NM_175081
P2RX5-TAX1BP3
P2RX5


P2RX5-TAX1BP3 read-through transcript
purinergic receptor P2X, ligand-gated ion channel, 5


chr13_-_26643952 0.258 NM_182488
USP12
ubiquitin specific peptidase 12
chr6_-_16869579 0.258 NM_000332
NM_001128164
ATXN1

ataxin 1

chr19_+_60851207 0.257 CCDC106
coiled-coil domain containing 106
chr6_+_135544138 0.257 NM_001130172
NM_001130173
NM_001161656
NM_001161657
NM_001161658
NM_001161659
NM_001161660
NM_005375
MYB







v-myb myeloblastosis viral oncogene homolog (avian)







chr7_+_128257698 0.256 NM_001127487
NM_001458
FLNC

filamin C, gamma

chr7_-_102044419 0.255 NM_001079877
NM_006989
RASA4

RAS p21 protein activator 4

chr7_-_102044374 0.255 RASA4
RAS p21 protein activator 4
chr1_+_148388719 0.255 NM_016274
PLEKHO1
pleckstrin homology domain containing, family O member 1
chr15_-_43267441 0.254 SHF
Src homology 2 domain containing F
chr19_+_14405216 0.253 PKN1
protein kinase N1
chr3_-_15875932 0.252 NM_015199
ANKRD28
ankyrin repeat domain 28
chr13_+_19430881 0.251 ZMYM2
zinc finger, MYM-type 2
chr6_+_89847183 0.250 PNRC1
proline-rich nuclear receptor coactivator 1
chr2_-_96899396 0.250 NM_017789
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr14_+_101297887 0.248 NM_001161725
NM_001161726
PPP2R5C

protein phosphatase 2, regulatory subunit B', gamma

chr1_+_65385799 0.247 NM_203464
NM_001005353
AK4

adenylate kinase 4

chr10_+_89613347 0.247 PTEN
phosphatase and tensin homolog
chr14_+_100262916 0.246 DLK1
delta-like 1 homolog (Drosophila)
chr6_-_109883639 0.246 MICAL1
microtubule associated monoxygenase, calponin and LIM domain containing 1
chr1_+_234372454 0.245 NM_003272
GPR137B
G protein-coupled receptor 137B
chr7_+_73341640 0.245 NM_003388
NM_032421
CLIP2

CAP-GLY domain containing linker protein 2

chr8_-_57286412 0.244 NM_001114634
NM_001114635
NM_002655
PLAG1


pleiomorphic adenoma gene 1


chr20_-_61039710 0.242 NM_022105
NM_033081
NM_080797
DIDO1


death inducer-obliterator 1


chr18_+_53253775 0.242 NM_004852
ONECUT2
one cut homeobox 2
chr7_+_116380790 0.241 ST7
suppression of tumorigenicity 7
chr19_-_45888259 0.240 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr21_+_16024241 0.236 NM_013396
USP25
ubiquitin specific peptidase 25
chr11_-_65396775 0.235 NM_016938
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr1_+_210525885 0.234 PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr14_+_100263066 0.232 DLK1
delta-like 1 homolog (Drosophila)
chr3_+_12304332 0.232 NM_005037
NM_138712
PPARG

peroxisome proliferator-activated receptor gamma

chr9_-_15500209 0.231 NM_021144
PSIP1
PC4 and SFRS1 interacting protein 1
chr1_+_210525792 0.231 PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr7_+_102502816 0.230 ARMC10
armadillo repeat containing 10
chr3_-_126257425 0.230 NM_020733
HEG1
HEG homolog 1 (zebrafish)
chr2_-_98713862 0.229 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr17_+_63252704 0.229 BPTF
bromodomain PHD finger transcription factor
chr1_-_109742020 0.228 NM_002959
SORT1
sortilin 1
chr20_+_44771532 0.228 NM_030777
SLC2A10
solute carrier family 2 (facilitated glucose transporter), member 10
chr12_+_110328126 0.228 NM_005475
SH2B3
SH2B adaptor protein 3
chr2_+_120820140 0.227 NM_002193
INHBB
inhibin, beta B
chr6_+_14225836 0.227 NM_001040280
NM_004233
CD83

CD83 molecule

chr13_-_26643775 0.226 USP12
ubiquitin specific peptidase 12
chr1_+_21708502 0.223 ALPL
alkaline phosphatase, liver/bone/kidney
chr4_-_74343169 0.222


chr3_+_53170254 0.221 NM_006254
NM_212539
PRKCD

protein kinase C, delta

chr8_-_80842452 0.220 NM_001040708
NM_012258
HEY1

hairy/enhancer-of-split related with YRPW motif 1

chr2_-_225615556 0.220 NM_014689
DOCK10
dedicator of cytokinesis 10
chr10_+_69314347 0.218 NM_012238
SIRT1
sirtuin 1
chrX_+_46977306 0.217 USP11
ubiquitin specific peptidase 11
chr2_+_203901160 0.217 NM_005759
ABI2
abl-interactor 2
chr16_+_1143241 0.217 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr11_-_92916161 0.216 NM_020179
C11orf75
chromosome 11 open reading frame 75
chr4_+_25931725 0.215 RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr7_+_119700924 0.214 NM_012281
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr10_+_69314714 0.214 SIRT1
sirtuin 1
chr19_+_18069596 0.213 NM_015016
MAST3
microtubule associated serine/threonine kinase 3
chr10_+_45189673 0.212 ALOX5
arachidonate 5-lipoxygenase
chr8_-_72918938 0.212 MSC
musculin
chr4_+_25931534 0.211 NM_015874
NM_203284
RBPJ

recombination signal binding protein for immunoglobulin kappa J region

chr6_+_132170847 0.208 NM_006208
ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr6_-_111243100 0.207 NM_015076
CDK19
cyclin-dependent kinase 19
chr19_-_18253436 0.207 JUND
jun D proto-oncogene
chr10_+_45189617 0.207 NM_000698
ALOX5
arachidonate 5-lipoxygenase
chr14_+_99220349 0.204 NM_006668
CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
chr6_-_111911106 0.203 NM_002912
REV3L
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
chr17_-_8006979 0.203 NM_014232
VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr19_+_659766 0.201 NM_001040134
NM_002579
PALM

paralemmin

chr9_-_36390817 0.200 NM_194328
NM_194332
RNF38

ring finger protein 38

chr6_-_112301123 0.196 NM_002037
FYN
FYN oncogene related to SRC, FGR, YES
chr8_-_74821610 0.196 STAU2
LOC729696
staufen, RNA binding protein, homolog 2 (Drosophila)
hypothetical protein LOC729696
chr5_-_81082614 0.196 SSBP2
single-stranded DNA binding protein 2
chr19_+_4920123 0.195 NM_015015
KDM4B
lysine (K)-specific demethylase 4B
chr1_-_149698272 0.195 POGZ
pogo transposable element with ZNF domain
chr6_+_71434305 0.194 SMAP1
small ArfGAP 1
chr19_+_10843244 0.194 NM_199141
CARM1
coactivator-associated arginine methyltransferase 1
chr16_-_3870686 0.194 CREBBP
CREB binding protein
chr8_-_72919161 0.193 MSC
musculin
chr6_-_143307976 0.193 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr17_-_74432671 0.192 TIMP2
TIMP metallopeptidase inhibitor 2
chr18_-_24011349 0.192 NM_001792
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr13_-_40138607 0.191 NM_002015
FOXO1
forkhead box O1
chr2_+_86521781 0.191 NM_018433
KDM3A
lysine (K)-specific demethylase 3A
chr22_+_38183262 0.189 NM_002409
MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr1_+_209566789 0.188 TRAF5
TNF receptor-associated factor 5
chr17_-_40750109 0.188 NM_003954
MAP3K14
mitogen-activated protein kinase kinase kinase 14
chr1_+_209566770 0.188 NM_001033910
TRAF5
TNF receptor-associated factor 5
chr1_-_149698516 0.187 NM_001194937
NM_001194938
NM_015100
NM_145796
POGZ



pogo transposable element with ZNF domain



chr19_-_44032388 0.186 HNRNPL
heterogeneous nuclear ribonucleoprotein L
chr4_+_37569093 0.186 NM_015173
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr6_+_42857540 0.185 KIAA0240
KIAA0240
chr17_+_63252087 0.184 NM_004459
NM_182641
BPTF

bromodomain PHD finger transcription factor

chr11_+_66790517 0.184 ADRBK1
adrenergic, beta, receptor kinase 1
chr2_+_162908869 0.182 GCA
grancalcin, EF-hand calcium binding protein
chr17_-_15407497 0.181 NM_001135036
NM_145301
FAM18B2-CDRT4
FAM18B2

FAM18B2-CDRT4 read-through transcript
family with sequence similarity 18, member B2

chr7_+_102502529 0.180 NM_001161009
NM_001161010
NM_001161011
NM_001161012
NM_001161013
NM_031905
ARMC10





armadillo repeat containing 10





chr17_-_78602931 0.179 NM_001009905
B3GNTL1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
chr20_-_61600834 0.178 NM_001958
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr1_-_198905619 0.177 DDX59
DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
chr12_+_102982365 0.177 NM_013320
HCFC2
host cell factor C2
chr3_-_38666122 0.175 NM_000335
NM_001099404
NM_001099405
NM_198056
NM_001160160
NM_001160161
SCN5A





sodium channel, voltage-gated, type V, alpha subunit





chr8_+_38877909 0.175 NM_021623
PLEKHA2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr2_+_54536780 0.175 NM_003128
SPTBN1
spectrin, beta, non-erythrocytic 1
chr5_-_39110235 0.173 RICTOR
RPTOR independent companion of MTOR, complex 2
chr1_+_110012166 0.173 NM_000848
NM_001142368
GSTM2

glutathione S-transferase mu 2 (muscle)

chr14_+_105024301 0.173 NM_001311
CRIP1
cysteine-rich protein 1 (intestinal)
chr14_+_105024576 0.172 CRIP1
cysteine-rich protein 1 (intestinal)
chr5_-_172687798 0.172 STC2
stanniocalcin 2
chr9_+_2005218 0.172 NM_003070
NM_139045
SMARCA2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

chr8_-_74821636 0.172 NM_001164380
NM_001164381
NM_001164382
NM_001164383
NM_001164385
NM_014393
STAU2





staufen, RNA binding protein, homolog 2 (Drosophila)





chr17_-_74432800 0.172 TIMP2
TIMP metallopeptidase inhibitor 2
chr7_+_127883117 0.172 NM_001098786
NM_013332
C7orf68

chromosome 7 open reading frame 68

chr7_+_149696901 0.170 REPIN1
replication initiator 1
chr12_-_99060590 0.170 UHRF1BP1L
UHRF1 binding protein 1-like
chr20_+_60130866 0.168 NM_144703
LSM14B
LSM14B, SCD6 homolog B (S. cerevisiae)
chr7_-_130891861 0.168 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr16_-_960982 0.168 NM_022773
LMF1
lipase maturation factor 1
chr6_-_79844606 0.168 PHIP
pleckstrin homology domain interacting protein
chr11_-_9243408 0.167 NM_015213
DENND5A
DENN/MADD domain containing 5A

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.36 9.82e-13 GO:0051252 regulation of RNA metabolic process
1.31 1.42e-11 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.32 1.83e-11 GO:0010468 regulation of gene expression
1.35 3.05e-11 GO:0006355 regulation of transcription, DNA-dependent
1.32 3.30e-11 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.36 9.20e-11 GO:0006464 protein modification process
1.30 6.84e-10 GO:0010556 regulation of macromolecule biosynthetic process
1.28 1.50e-09 GO:0031326 regulation of cellular biosynthetic process
1.28 1.85e-09 GO:0051171 regulation of nitrogen compound metabolic process
1.33 2.79e-09 GO:0043412 macromolecule modification
1.28 3.16e-09 GO:0009889 regulation of biosynthetic process
1.23 3.86e-09 GO:0031323 regulation of cellular metabolic process
1.24 5.59e-09 GO:0060255 regulation of macromolecule metabolic process
1.23 6.22e-09 GO:0080090 regulation of primary metabolic process
1.35 2.80e-08 GO:0023051 regulation of signaling
1.20 5.35e-08 GO:0019222 regulation of metabolic process
1.18 1.16e-07 GO:0044260 cellular macromolecule metabolic process
1.13 6.98e-07 GO:0050794 regulation of cellular process
1.70 1.89e-06 GO:0016568 chromatin modification
1.24 6.54e-06 GO:0044267 cellular protein metabolic process
1.40 9.64e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.11 1.20e-05 GO:0050789 regulation of biological process
1.51 1.53e-05 GO:0010629 negative regulation of gene expression
1.12 2.66e-05 GO:0044237 cellular metabolic process
1.90 3.43e-05 GO:0016569 covalent chromatin modification
1.90 4.84e-05 GO:0016570 histone modification
1.10 8.08e-05 GO:0065007 biological regulation
1.14 9.63e-05 GO:0043170 macromolecule metabolic process
1.30 1.02e-04 GO:0009966 regulation of signal transduction
1.37 2.37e-04 GO:0006351 transcription, DNA-dependent
1.51 6.28e-04 GO:0006325 chromatin organization
1.47 6.34e-04 GO:0051253 negative regulation of RNA metabolic process
1.40 7.14e-04 GO:0006468 protein phosphorylation
1.43 1.13e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.36 1.82e-03 GO:0048699 generation of neurons
1.34 1.96e-03 GO:0022008 neurogenesis
1.40 1.99e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.39 2.25e-03 GO:0009890 negative regulation of biosynthetic process
1.41 2.52e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.26 2.64e-03 GO:0007399 nervous system development
1.40 2.73e-03 GO:0051254 positive regulation of RNA metabolic process
1.41 2.90e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.41 3.49e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.54 3.55e-03 GO:0018193 peptidyl-amino acid modification
1.31 3.59e-03 GO:0006793 phosphorus metabolic process
1.31 3.59e-03 GO:0006796 phosphate metabolic process
1.31 3.59e-03 GO:0032774 RNA biosynthetic process
1.45 3.79e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.32 4.03e-03 GO:0009892 negative regulation of metabolic process
1.10 4.28e-03 GO:0044238 primary metabolic process
1.17 4.69e-03 GO:0019538 protein metabolic process
1.20 5.29e-03 GO:0048523 negative regulation of cellular process
1.33 5.92e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.18 8.93e-03 GO:0071842 cellular component organization at cellular level
1.39 9.00e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
2.04 1.07e-02 GO:0040029 regulation of gene expression, epigenetic
1.18 1.45e-02 GO:0048519 negative regulation of biological process
1.36 1.73e-02 GO:0010628 positive regulation of gene expression
1.34 2.03e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.09 2.54e-02 GO:0008152 metabolic process
1.32 2.56e-02 GO:0016310 phosphorylation
1.14 2.77e-02 GO:0032502 developmental process
1.22 2.77e-02 GO:0006996 organelle organization
1.30 2.89e-02 GO:0050793 regulation of developmental process
1.32 3.48e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
2.01 4.52e-02 GO:0008629 induction of apoptosis by intracellular signals

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.08 3.11e-11 GO:0005622 intracellular
1.18 4.70e-11 GO:0005634 nucleus
1.08 1.77e-10 GO:0044424 intracellular part
1.10 4.37e-10 GO:0043226 organelle
1.10 9.27e-10 GO:0043229 intracellular organelle
1.10 1.52e-08 GO:0043227 membrane-bounded organelle
1.10 2.65e-08 GO:0043231 intracellular membrane-bounded organelle
1.33 7.44e-07 GO:0005654 nucleoplasm
1.24 8.99e-05 GO:0031981 nuclear lumen
2.79 1.06e-04 GO:0035770 RNA granule
1.21 2.23e-04 GO:0044428 nuclear part
2.02 1.53e-03 GO:0016585 chromatin remodeling complex
1.34 3.34e-03 GO:0044451 nucleoplasm part
2.98 4.72e-03 GO:0000932 cytoplasmic mRNA processing body
1.17 1.39e-02 GO:0070013 intracellular organelle lumen
1.16 1.61e-02 GO:0031974 membrane-enclosed lumen
1.16 1.91e-02 GO:0043233 organelle lumen

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.49 1.01e-10 GO:0030528 transcription regulator activity
1.44 2.98e-08 GO:0001071 nucleic acid binding transcription factor activity
1.44 2.98e-08 GO:0003700 sequence-specific DNA binding transcription factor activity
1.12 5.85e-08 GO:0005515 protein binding
1.25 2.43e-06 GO:0003677 DNA binding
1.06 4.28e-06 GO:0005488 binding
1.59 4.79e-06 GO:0004674 protein serine/threonine kinase activity
1.20 5.63e-06 GO:0003676 nucleic acid binding
1.25 1.39e-04 GO:0008270 zinc ion binding
1.41 2.47e-04 GO:0043565 sequence-specific DNA binding
1.57 7.41e-04 GO:0016563 transcription activator activity
1.69 1.48e-03 GO:0000975 regulatory region DNA binding
1.69 1.48e-03 GO:0001067 regulatory region nucleic acid binding
1.69 1.48e-03 GO:0044212 transcription regulatory region DNA binding
1.15 1.54e-03 GO:0046872 metal ion binding
1.70 1.71e-03 GO:0010843 promoter binding
1.36 1.83e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.14 2.54e-03 GO:0043167 ion binding
1.34 2.79e-03 GO:0016301 kinase activity
1.45 2.90e-03 GO:0019904 protein domain specific binding
1.39 3.15e-03 GO:0004672 protein kinase activity
1.14 3.45e-03 GO:0043169 cation binding
1.68 6.31e-03 GO:0003682 chromatin binding
1.19 1.01e-02 GO:0046914 transition metal ion binding
1.50 1.72e-02 GO:0008134 transcription factor binding
1.31 2.33e-02 GO:0019899 enzyme binding
2.28 2.37e-02 GO:0004702 receptor signaling protein serine/threonine kinase activity
1.27 4.95e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups