Motif ID: ATF5_CREB3.p2

Z-value: 1.289


Transcription factors associated with ATF5_CREB3.p2:

Gene SymbolEntrez IDGene Name
ATF5 22809 activating transcription factor 5
CREB3 10488 cAMP responsive element binding protein 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CREB3chr9_+_35722207-0.449.0e-02Click!
ATF5chr19_+_551242110.039.1e-01Click!


Activity profile for motif ATF5_CREB3.p2.

activity profile for motif ATF5_CREB3.p2


Sorted Z-values histogram for motif ATF5_CREB3.p2

Sorted Z-values for motif ATF5_CREB3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF5_CREB3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_75699652 2.489 NM_001657
AREG
amphiregulin
chr4_+_75529716 2.403 NM_001657
AREG
amphiregulin
chr14_+_67156386 1.960 ARG2
arginase, type II
chr21_-_43671355 1.571 NM_173354
SIK1
salt-inducible kinase 1
chr4_+_85723080 1.484 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr1_+_154297588 1.406 NM_020387
RAB25
RAB25, member RAS oncogene family
chr16_+_22733307 1.378 NM_006043
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr2_+_74914742 1.303 HK2
hexokinase 2
chr5_-_1935764 1.252 NM_016358
IRX4
iroquois homeobox 4
chr20_-_55718351 1.230 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr14_+_67156405 1.101 ARG2
arginase, type II
chr18_+_18767275 1.036 NM_002894
RBBP8
retinoblastoma binding protein 8
chr1_+_26368969 0.989 NM_015871
ZNF593
zinc finger protein 593
chr8_-_22606653 0.952 NM_004430
EGR3
early growth response 3
chr12_+_4253143 0.942 NM_001759
CCND2
cyclin D2
chr8_+_61753793 0.931 NM_017780
CHD7
chromodomain helicase DNA binding protein 7
chr5_+_137829065 0.924 EGR1
early growth response 1
chr12_-_121946581 0.920 VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr14_+_67156323 0.856 NM_001172
ARG2
arginase, type II
chr1_-_183552833 0.839 IVNS1ABP
influenza virus NS1A binding protein
chr6_+_30402203 0.819


chr21_-_42060266 0.793 NM_020639
RIPK4
receptor-interacting serine-threonine kinase 4
chr21_-_42060334 0.785 RIPK4
receptor-interacting serine-threonine kinase 4
chr2_-_220116508 0.785 NM_024536
CHPF
chondroitin polymerizing factor
chr1_-_183553083 0.761 NM_006469
IVNS1ABP
influenza virus NS1A binding protein
chr12_+_131194967 0.760 NOC4L
nucleolar complex associated 4 homolog (S. cerevisiae)
chr2_-_60634271 0.746 BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr12_-_121946561 0.719


chr5_-_138238953 0.714 NM_015564
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr7_+_116447499 0.684 ST7
suppression of tumorigenicity 7
chr10_+_103901922 0.681 NM_004741
NOLC1
nucleolar and coiled-body phosphoprotein 1
chr1_+_231816372 0.672 NM_002245
KCNK1
potassium channel, subfamily K, member 1
chr2_-_60633908 0.671 NM_018014
NM_022893
NM_138559
BCL11A


B-cell CLL/lymphoma 11A (zinc finger protein)


chr12_-_121946635 0.651 NM_024667
VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr1_+_116717552 0.642 ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr5_-_138238891 0.634 CTNNA1
LRRTM2
catenin (cadherin-associated protein), alpha 1, 102kDa
leucine rich repeat transmembrane neuronal 2
chr4_-_56197115 0.633 NM_006681
NMU
neuromedin U
chr2_+_60962206 0.632 REL
v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr8_-_131097828 0.627 FAM49B
family with sequence similarity 49, member B
chr1_+_1994943 0.610 NM_001033581
PRKCZ
protein kinase C, zeta
chr1_-_1274618 0.605 DVL1
dishevelled, dsh homolog 1 (Drosophila)
chr3_+_195336631 0.605 HES1
hairy and enhancer of split 1, (Drosophila)
chr7_-_140270749 0.604 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chrX_-_13745134 0.600 GPM6B
glycoprotein M6B
chr21_-_33836994 0.600 NM_001136005
NM_001136006
GART

phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase

chrX_-_13745108 0.597 GPM6B
glycoprotein M6B
chr1_-_201194033 0.596 ADIPOR1
adiponectin receptor 1
chr8_-_29263714 0.594 NM_001394
DUSP4
dual specificity phosphatase 4
chr8_-_110730183 0.589 NM_001099747
NM_001099748
NM_001099749
NM_001099750
NM_017786
SYBU




syntabulin (syntaxin-interacting)




chr17_+_54124952 0.587 NM_002876
NM_058216
RAD51C

RAD51 homolog C (S. cerevisiae)

chr8_-_131097856 0.585 FAM49B
family with sequence similarity 49, member B
chr1_+_116717461 0.580 ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr14_-_35348086 0.580 NM_014990
NM_194301
RALGAPA1

Ral GTPase activating protein, alpha subunit 1 (catalytic)

chr17_+_54124928 0.571 RAD51C
RAD51 homolog C (S. cerevisiae)
chr1_-_201194044 0.570 ADIPOR1
adiponectin receptor 1
chr1_-_201194083 0.570 NM_015999
ADIPOR1
adiponectin receptor 1
chr3_+_195336625 0.569 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr19_+_4353658 0.566 NM_005483
CHAF1A
chromatin assembly factor 1, subunit A (p150)
chr3_-_151963577 0.565 SIAH2
seven in absentia homolog 2 (Drosophila)
chr3_-_151963607 0.564 SIAH2
seven in absentia homolog 2 (Drosophila)
chr16_-_4528739 0.557 NM_001199055
NM_001199056
NM_013399
C16orf5


chromosome 16 open reading frame 5


chr5_+_137829077 0.557 NM_001964
EGR1
early growth response 1
chr12_+_131194931 0.555 NM_024078
NOC4L
nucleolar complex associated 4 homolog (S. cerevisiae)
chr1_+_116717404 0.539 ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr1_-_16355013 0.536 NM_004431
EPHA2
EPH receptor A2
chr20_-_44034346 0.535 ZNF335
zinc finger protein 335
chr13_+_72531098 0.534 NM_001730
KLF5
Kruppel-like factor 5 (intestinal)
chr16_-_66252103 0.530 NM_001082486
NM_001082487
NM_022914
ACD


adrenocortical dysplasia homolog (mouse)


chr5_-_175896829 0.523 NM_014901
RNF44
ring finger protein 44
chr12_-_31370305 0.519 FAM60A
family with sequence similarity 60, member A
chr5_-_95323353 0.517 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chr1_+_231816540 0.512 KCNK1
potassium channel, subfamily K, member 1
chr12_-_31370387 0.509 NM_001135811
NM_021238
NM_001135812
FAM60A


family with sequence similarity 60, member A


chr12_-_31370351 0.508 FAM60A
family with sequence similarity 60, member A
chr1_-_201194062 0.503 ADIPOR1
adiponectin receptor 1
chr1_+_39229474 0.498 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr11_+_3775529 0.495 NM_001145438
PGAP2
post-GPI attachment to proteins 2
chr21_+_17807167 0.491 NM_001338
CXADR
coxsackie virus and adenovirus receptor
chr6_-_34772565 0.488 NM_022758
NM_024294
C6orf106

chromosome 6 open reading frame 106

chr2_+_60962279 0.488 REL
v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr9_-_139473606 0.486 NM_001130969
NM_001130970
NM_001130971
NM_001178064
NM_015537
NELF




nasal embryonic LHRH factor




chr3_-_33734544 0.484 CLASP2
cytoplasmic linker associated protein 2
chrX_+_24077649 0.484 NM_001178086
NM_001178095
NM_001178084
NM_001178085
NM_003410
ZFX




zinc finger protein, X-linked




chr1_+_116717317 0.483 NM_000701
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr1_+_51855343 0.482 OSBPL9
oxysterol binding protein-like 9
chr6_+_107066422 0.476 NM_001624
AIM1
absent in melanoma 1
chr1_+_161027115 0.474 NM_016371
HSD17B7
hydroxysteroid (17-beta) dehydrogenase 7
chr8_-_102872354 0.474 NCALD
neurocalcin delta
chr19_-_48661563 0.470 NM_014400
LYPD3
LY6/PLAUR domain containing 3
chr8_-_102872372 0.465 NCALD
neurocalcin delta
chr3_+_186786655 0.463 NM_021627
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr14_-_66948612 0.461 PLEK2
pleckstrin 2
chr3_-_12775718 0.460 NM_018306
TMEM40
transmembrane protein 40
chr5_-_43349249 0.460 HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chrX_-_13745234 0.460 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr10_+_35524835 0.458 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
CREM




cAMP responsive element modulator




chr19_-_18253259 0.455


chr17_-_632135 0.453 NM_016080
GLOD4
glyoxalase domain containing 4
chr16_-_3707450 0.449 NM_016292
TRAP1
TNF receptor-associated protein 1
chr11_+_18372687 0.449 LDHA
lactate dehydrogenase A
chr11_+_18372682 0.447 LDHA
lactate dehydrogenase A
chr16_-_66251611 0.447 ACD
adrenocortical dysplasia homolog (mouse)
chr3_+_44992733 0.446 NM_015004
EXOSC7
exosome component 7
chr14_+_93562500 0.438 OTUB2
OTU domain, ubiquitin aldehyde binding 2
chr20_+_18436167 0.435 NM_006363
NM_032985
NM_032986
NM_001172746
SEC23B



Sec23 homolog B (S. cerevisiae)



chr9_-_139473569 0.433 NELF
nasal embryonic LHRH factor
chr6_+_44322764 0.430 NM_007355
HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr11_-_3775312 0.429 NUP98
nucleoporin 98kDa
chr2_+_118288753 0.428 DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr2_+_74610751 0.428 HTRA2
HtrA serine peptidase 2
chr17_-_37034288 0.427 NM_000422
KRT17
keratin 17
chr17_+_24095135 0.426 NM_004295
TRAF4
TNF receptor-associated factor 4
chr12_+_70434920 0.426 NM_014999
RAB21
RAB21, member RAS oncogene family
chr15_+_64466161 0.424 NM_002755
MAP2K1
mitogen-activated protein kinase kinase 1
chrX_+_24077782 0.424 ZFX
zinc finger protein, X-linked
chr2_+_118288754 0.419 DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr4_-_122964232 0.419 CCNA2
cyclin A2
chr1_-_201193892 0.417 ADIPOR1
adiponectin receptor 1
chr22_+_25209812 0.417 NM_001013694
SRRD
SRR1 domain containing
chr16_+_66614645 0.416 NM_017803
DUS2L
dihydrouridine synthase 2-like, SMM1 homolog (S. cerevisiae)
chr16_+_53522611 0.416 NM_005853
IRX5
iroquois homeobox 5
chr6_+_138230045 0.416 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr5_-_16670085 0.415 NM_001034850
FAM134B
family with sequence similarity 134, member B
chr5_-_43349338 0.414 NM_001098272
NM_002130
HMGCS1

3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)

chr4_+_39137038 0.414 NM_006859
NM_194451
LIAS

lipoic acid synthetase

chr2_+_172530120 0.413 HAT1
histone acetyltransferase 1
chr2_+_118288724 0.408 NM_006773
DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr11_+_18372689 0.408 LDHA
lactate dehydrogenase A
chr1_+_40399618 0.407 NM_012421
RLF
rearranged L-myc fusion
chr14_-_54438913 0.405 NM_000161
NM_001024024
NM_001024070
NM_001024071
GCH1



GTP cyclohydrolase 1



chr12_-_14847582 0.398 WBP11
WW domain binding protein 11
chr2_+_105320247 0.395 C2orf49
chromosome 2 open reading frame 49
chr2_-_27384617 0.392 NM_003353
UCN
urocortin
chr2_-_10506033 0.391 ODC1
ornithine decarboxylase 1
chr1_+_29435534 0.390 NM_001195001
NM_005704
NM_133177
NM_133178
PTPRU



protein tyrosine phosphatase, receptor type, U



chr2_-_73373956 0.390 NM_001965
EGR4
early growth response 4
chr9_-_130683997 0.389 NM_001122671
NM_001122672
NM_004059
CCBL1


cysteine conjugate-beta lyase, cytoplasmic


chr11_+_18372708 0.387 LDHA
lactate dehydrogenase A
chrX_-_100549561 0.386 NM_000169
GLA
galactosidase, alpha
chr17_-_71960867 0.378 NM_022066
UBE2O
ubiquitin-conjugating enzyme E2O
chr5_+_148186348 0.377 NM_000024
ADRB2
adrenergic, beta-2-, receptor, surface
chr10_-_64246129 0.376 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr11_-_118433025 0.373 HYOU1
hypoxia up-regulated 1
chr1_-_113300138 0.372 NM_001166496
SLC16A1
solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
chr11_+_66367458 0.372 NM_001032279
NM_005133
RCE1

RCE1 homolog, prenyl protein peptidase (S. cerevisiae)

chr1_+_40399642 0.371 RLF
rearranged L-myc fusion
chr6_+_111302679 0.371 NM_001634
NM_001033059
AMD1

adenosylmethionine decarboxylase 1

chr6_-_29703725 0.371 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr17_-_8092098 0.370 NM_025099
CTC1
CTS telomere maintenance complex component 1
chr17_-_44058612 0.367 NM_024017
HOXB9
homeobox B9
chr3_+_44992753 0.366 EXOSC7
exosome component 7
chr2_-_10505724 0.364 ODC1
ornithine decarboxylase 1
chr1_-_113300351 0.363 NM_003051
SLC16A1
solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
chr9_-_139100923 0.361 LOC100289341
similar to hCG2022304
chrX_-_33267646 0.361 NM_000109
DMD
dystrophin
chr6_+_44322831 0.360 HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr2_-_10505902 0.359 NM_002539
ODC1
ornithine decarboxylase 1
chr20_-_10602429 0.359 NM_000214
JAG1
jagged 1
chr2_-_112358013 0.359 ANAPC1
anaphase promoting complex subunit 1
chr1_+_240078167 0.358 EXO1
exonuclease 1
chr3_+_159771646 0.357 NM_001130156
NM_001130157
NM_001195432
NM_001195433
NM_001195434
NM_022443
MLF1





myeloid leukemia factor 1





chr1_-_38046433 0.357 YRDC
yrdC domain containing (E. coli)
chr1_-_53566171 0.356 NM_001018054
NM_004631
NM_017522
LRP8


low density lipoprotein receptor-related protein 8, apolipoprotein e receptor


chr1_+_240078094 0.356 NM_130398
EXO1
exonuclease 1
chrX_-_100549444 0.355 GLA
galactosidase, alpha
chr7_+_143683365 0.354 NM_005435
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr1_-_38046410 0.353 YRDC
yrdC domain containing (E. coli)
chr6_+_28156460 0.351 NM_003447
ZNF165
zinc finger protein 165
chr5_+_44844724 0.347 NM_016640
MRPS30
mitochondrial ribosomal protein S30
chr17_+_632356 0.346 RNMTL1
RNA methyltransferase like 1
chr6_+_30693464 0.345 NM_014046
MRPS18B
mitochondrial ribosomal protein S18B
chr7_-_36372971 0.344 NM_015314
KIAA0895
KIAA0895
chr10_+_13243553 0.344 NM_018518
NM_182751
MCM10

minichromosome maintenance complex component 10

chr7_-_45117797 0.341 TBRG4
transforming growth factor beta regulator 4
chr12_-_14847675 0.340 WBP11
WW domain binding protein 11
chr16_-_86460529 0.338 NM_003486
SLC7A5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
chr22_-_25209724 0.336 HPS4
Hermansky-Pudlak syndrome 4
chr2_+_105320440 0.335 NM_024093
C2orf49
chromosome 2 open reading frame 49
chr2_+_73909603 0.334 NM_006463
NM_213622
STAMBP

STAM binding protein

chr16_-_20819061 0.332 NM_173475
DCUN1D3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr17_-_2187427 0.331 NM_018128
TSR1
TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
chr12_-_14847634 0.331 NM_016312
WBP11
WW domain binding protein 11
chr1_-_155053124 0.330 NM_001161441
NM_001161442
NM_001161444
NM_003975
SH2D2A



SH2 domain containing 2A



chr4_+_4439618 0.330 D4S234E
DNA segment on chromosome 4 (unique) 234 expressed sequence
chr6_+_64340408 0.329 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr22_-_25209761 0.329 NM_022081
HPS4
Hermansky-Pudlak syndrome 4
chr3_+_190831909 0.328 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr6_-_31882558 0.328 LSM2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr1_-_38046270 0.325 YRDC
yrdC domain containing (E. coli)
chr20_+_34635362 0.325 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr3_-_197293331 0.325 TFRC
transferrin receptor (p90, CD71)
chr5_+_50714996 0.325 ISL1
ISL LIM homeobox 1
chr22_+_20101661 0.324 NM_015094
HIC2
hypermethylated in cancer 2
chr2_+_73909579 0.322 NM_201647
STAMBP
STAM binding protein
chrX_-_13744933 0.321 GPM6B
glycoprotein M6B
chr17_+_50697319 0.319 NM_002126
HLF
hepatic leukemia factor
chr6_-_106880229 0.319 ATG5
ATG5 autophagy related 5 homolog (S. cerevisiae)
chr1_-_46957377 0.316 KIAA0494
KIAA0494
chr19_+_1892184 0.315 CSNK1G2
casein kinase 1, gamma 2
chr2_-_112358204 0.315 NM_022662
ANAPC1
anaphase promoting complex subunit 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.37 7.18e-17 GO:0044260 cellular macromolecule metabolic process
1.52 2.28e-13 GO:0090304 nucleic acid metabolic process
1.56 1.45e-12 GO:0010467 gene expression
1.24 1.23e-11 GO:0044237 cellular metabolic process
1.29 1.74e-11 GO:0043170 macromolecule metabolic process
1.41 4.32e-11 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.55 7.08e-11 GO:0016070 RNA metabolic process
1.36 2.99e-10 GO:0034641 cellular nitrogen compound metabolic process
1.52 2.01e-09 GO:0009059 macromolecule biosynthetic process
1.52 2.65e-09 GO:0034645 cellular macromolecule biosynthetic process
1.21 4.34e-09 GO:0044238 primary metabolic process
1.33 8.31e-09 GO:0006807 nitrogen compound metabolic process
1.38 1.07e-07 GO:0044249 cellular biosynthetic process
1.36 3.34e-07 GO:0009058 biosynthetic process
1.17 3.99e-07 GO:0008152 metabolic process
1.61 6.70e-06 GO:0006351 transcription, DNA-dependent
2.11 6.91e-06 GO:0008380 RNA splicing
1.74 1.02e-05 GO:0006396 RNA processing
2.34 1.22e-05 GO:0000375 RNA splicing, via transesterification reactions
2.32 3.78e-05 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.32 3.78e-05 GO:0000398 nuclear mRNA splicing, via spliceosome
1.54 6.50e-05 GO:0032774 RNA biosynthetic process
1.70 7.62e-04 GO:0016071 mRNA metabolic process
1.08 1.14e-03 GO:0009987 cellular process
1.82 1.14e-03 GO:0006397 mRNA processing
1.24 2.15e-03 GO:0060255 regulation of macromolecule metabolic process
1.28 3.66e-03 GO:0044267 cellular protein metabolic process
2.33 8.59e-03 GO:0050657 nucleic acid transport
2.33 8.59e-03 GO:0050658 RNA transport
2.33 8.59e-03 GO:0051236 establishment of RNA localization
1.50 1.09e-02 GO:0046907 intracellular transport
2.27 1.59e-02 GO:0006403 RNA localization
1.21 2.09e-02 GO:0031323 regulation of cellular metabolic process
1.25 2.11e-02 GO:0031326 regulation of cellular biosynthetic process
2.32 2.76e-02 GO:0051028 mRNA transport
1.24 2.98e-02 GO:0009889 regulation of biosynthetic process
2.14 4.66e-02 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
2.01 4.87e-02 GO:0006913 nucleocytoplasmic transport

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.54 1.03e-15 GO:0044428 nuclear part
1.28 6.94e-14 GO:0005634 nucleus
1.56 1.77e-13 GO:0031981 nuclear lumen
1.18 5.59e-13 GO:0043227 membrane-bounded organelle
1.18 8.40e-13 GO:0043231 intracellular membrane-bounded organelle
1.46 5.27e-12 GO:0070013 intracellular organelle lumen
1.12 2.64e-11 GO:0044424 intracellular part
1.44 7.66e-11 GO:0043233 organelle lumen
1.43 1.19e-10 GO:0031974 membrane-enclosed lumen
1.14 1.32e-10 GO:0043226 organelle
1.14 1.39e-10 GO:0043229 intracellular organelle
1.10 9.42e-10 GO:0005622 intracellular
1.57 1.16e-09 GO:0005654 nucleoplasm
1.22 3.01e-08 GO:0044446 intracellular organelle part
1.21 5.57e-08 GO:0044422 organelle part
4.98 6.04e-04 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
1.61 8.32e-04 GO:0005694 chromosome
1.67 1.32e-03 GO:0044427 chromosomal part
1.60 3.37e-03 GO:0030529 ribonucleoprotein complex
2.18 8.29e-03 GO:0005681 spliceosomal complex
1.56 1.49e-02 GO:0005730 nucleolus
1.46 1.62e-02 GO:0044451 nucleoplasm part
2.48 2.36e-02 GO:0071013 catalytic step 2 spliceosome
1.21 4.34e-02 GO:0043228 non-membrane-bounded organelle
1.21 4.34e-02 GO:0043232 intracellular non-membrane-bounded organelle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.34 1.13e-08 GO:0003676 nucleic acid binding
1.69 1.35e-07 GO:0003723 RNA binding
1.16 1.94e-07 GO:0005515 protein binding
1.34 9.36e-06 GO:0000166 nucleotide binding
1.51 1.10e-04 GO:0001071 nucleic acid binding transcription factor activity
1.51 1.10e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.39 1.71e-04 GO:0030554 adenyl nucleotide binding
1.49 2.14e-04 GO:0030528 transcription regulator activity
1.34 2.62e-04 GO:0017076 purine nucleotide binding
1.38 2.82e-04 GO:0032559 adenyl ribonucleotide binding
1.33 3.73e-04 GO:0032553 ribonucleotide binding
1.33 3.73e-04 GO:0032555 purine ribonucleotide binding
1.37 5.26e-04 GO:0005524 ATP binding
1.33 6.79e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.30 1.05e-03 GO:0003677 DNA binding
1.54 3.44e-03 GO:0043565 sequence-specific DNA binding